Evaluation of CAZyme Classifiers dbCAN and CUPP
Emma E. M. Hobbs
2023-07-26
An independent and comprehensive evaluation of the CAZyme classifiers: - dbCAN4 - CUPP - HMMER (dbCAN4) - dbCAN-sub (dbCAN4) - DIAMOND (dbCAN4)
Evaluating performance of: - Binary CAZyme/non-CAZyme classification - Test set dependent performance of CAZyme/non-CAZyme classification - Binary classification per CAZy class - Multilabel CAZy class classification - Binary classification per CAZy family - Multilabel CAZy family classification
1 CAZyme classifier references and names
The CAZyme classifier dbCAN is available as a webserver and a standalone tool. In this evaluation the standalone tool was used, and is referred to as dbCAN, references to the webserver are defined as the dbCAN webserver. The version numbers of the standalone tool and the webserver are independent of one another: * The dbCAN2 webserver initally ran dbCAN version 2 (referred to as dbCAN2) * The dbCAN2 webserver than implememented the standalone dbCAN version 3 (referred to as dbCAN3) * The dbCAN3 webserver implements the standalone dbCAN version 4 (referred to as dbCAN4)
All references to implementing HMMER and DIAMOND refer to the implementation of these tools by dbCAN. For this evaluation, specifically the implementation of HMMER and DIAMOND by dbCAN4.
Han Zhang and others, dbCAN2: a meta server for automated carbohydrate-active enzyme annotation, Nucleic Acids Research, Volume 46, Issue W1, 2 July 2018, Pages W95–W101
Zheng J, Ge Q, Yan Y, Zhang X, Huang L, Yin Y. dbCAN3: automated carbohydrate-active enzyme and substrate annotation. Nucleic Acids Res. 2023 Jul 5;51(W1):W115-W121
Xu J, Zhang H, Zheng J, Dovoedo P, Yin Y. eCAMI: simultaneous classification and motif identification for enzyme annotation. Bioinformatics. 2020 Apr 1;36(7):2068-2075
Barrett, K., Lange, L. Peptide-based functional annotation of carbohydrate-active enzymes by conserved unique peptide patterns (CUPP). Biotechnol Biofuels 12, 102 (2019). https://doi.org/10.1186/s13068-019-1436-5
Eddy SR. Profile hidden Markov models. Bioinformatics. 1998;14(9):755-63.
Buchfink, B., Xie, C. & Huson, D. Fast and sensitive protein alignment using DIAMOND. Nat Methods 12, 59–60 (2015). https://doi.org/10.1038/nmeth.3176
2 Introduction
CAZyme classifiers analyse query protein sequence and predict CAZyme domains and associated CAZy family annotations. This enables exploratory analysis of CAZyme complements not presently catalogued in the CAZy database (www.cazy.org). Each CAZyme classifier implements a different method to predict CAZy family annotations.
We previously published an evaluation of dbCAN2, eCAMI and CUPP (Hobbs et al., 2021). Since then, two standalone versions of dbCAN have been released (dbCAN3 and dbCAN4). Additionally, the previous analysis was limited to 70 genomes, over weighted towards bacterial genomes. To address these points, we present here an independent and comprehensive evaluation of the CAZyme classifiers: * dbCAN2 (v2.0.11) * dbCAN3 (v3.0.7) * dbCAN4 (v4.0.0) * eCAMI (implemented by dbCAN_3 (3.0.7)) * CUPP (v???) * HMMER (from dbCAN4) * dbCAN-sub (from dbCAN4) * DIAMOND (from dbCAN4)
Evaluating performance of: * Binary CAZyme/non-CAZyme classification * Test set dependent performance of CAZyme/non-CAZyme classification * Binary classification per CAZy class * Multilabel CAZy class classification * Binary classification per CAZy family * Multilabel CAZy family classification
Hobbs, Emma E. M.; Gloster, Tracey M.; Chapman, Sean; Pritchard, Leighton (2021). Microbiology Society Annual Conference 2021. figshare. Poster. https://doi.org/10.6084/m9.figshare.14370836.v3
3 Test sets
A single test set of 100 CAZymes and 100 non-CAZymes with the highest sequence similarity (rated by bit-score ratio) was created per genomic assembly selected to be included in the benchmark test set.
Choosing the 100 non-CAZymes with the highest sequence similarity was devised to increase the probability of causing confusion, to gather a better idea of the expected performance when using the classifiers. An equal number of CAZymes to non-CAZymes was selected to prevent over representation of one population over the other.
For inclusion of a genomic assembly for the creation of a test set, the assembly had to meet of all the following criteria:
- Contains at least 100 CAZymes
- Contains at least 100 non-CAZymes
- Has an ‘Assembly level’ of ‘Complete Genome’ in the NCBI Assembly database
- Protein records are still present in NCBI
- Not listed as an ‘Anomalous assembly’ in the NCBI Assembly database
The genomic assemblies were also chosen from a range of taxonomies to provide as informative image of the performance of the classifiers over a range of datasets that users may wish to analyse.
We took the 70 test sets used in the previous evaluation (Hobbs et al., 2021), and added an additional 10 genomes.
## [1] "Mean percentage of genome incorporated in the CAZome across all test sets:"## [1] 3.22## [1] "Standard deviation of the percentage of genome incorporated in the CAZome across all test sets:"## [1] 1.17## [1] "Mean percentage of CAZomes incorporated in the test set across all genomes:"## [1] 58.6## [1] "Standard deviation of the percentage of CAZome incorporated in the test set across all genomes:"## [1] 27.55
Figure 3.1: Histogram of CAZome coverage of the test sets for each respective source genomic assembly, overlayed by a box and whisker plot of the percentage of the CAZome incorproated in the test set.
4 CAZyme/non-CAZyme classification
The assignment of CAZy family annotations by a CAZyme classifier identifies the protein as a CAZyme. If no CAZy family annotations are assigned to a protein by a CAZyme classifier, the tool identified the protein as a non-CAZyme. Here we evaluate the performance of each CAZyme classifier to differentiate between CAZymes and non-CAZymes (defined as proteins catalogued and not catalogued in CAZy respectively).
4.1 Summary statistics
For every classifier-test set pair, the specificity, sensitivity, prevision, F1-score and accuracy was calculated. The mean of each statistical parameter was calculated for each classifier across all tests, to represent the overall performance of each classifier. The 95% confidence interval (CI) was also calculated owing the tendancy of the mean to skew towards 1. These results are presented in table 4.1.
| Classifier | Spec Mean | Spec Standard Deviation | Spec Lower CI | Spec Upper CI | Sens Mean | Sens Standard Deviation | Sens Lower CI | Sens Upper CI | Prec Mean | Prec Standard Deviation | Prec Lower CI | Prec Upper CI | F1-score Mean | F1-score Standard Deviation | F1-score Lower CI | F1-score Upper CI | Acc Mean | Acc Standard Deviation | Acc Lower CI | Acc Upper CI |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CUPP | 0.9818 | 0.0487 | 0.9709 | 0.9926 | 0.8539 | 0.0744 | 0.8373 | 0.8704 | 0.9812 | 0.0454 | 0.9711 | 0.9913 | 0.9109 | 0.0520 | 0.8994 | 0.9225 | 0.9178 | 0.0460 | 0.9076 | 0.9280 |
| dbCAN_4 | 0.9622 | 0.0763 | 0.9453 | 0.9792 | 0.9841 | 0.0640 | 0.9699 | 0.9984 | 0.9672 | 0.0555 | 0.9549 | 0.9796 | 0.9733 | 0.0531 | 0.9614 | 0.9851 | 0.9732 | 0.0491 | 0.9623 | 0.9841 |
| dbCAN_4:dbCAN-sub | 0.9775 | 0.0529 | 0.9657 | 0.9893 | 0.9498 | 0.0729 | 0.9335 | 0.9660 | 0.9792 | 0.0432 | 0.9696 | 0.9888 | 0.9618 | 0.0563 | 0.9493 | 0.9744 | 0.9636 | 0.0449 | 0.9536 | 0.9736 |
| dbCAN_4:DIAMOND | 0.9668 | 0.0744 | 0.9502 | 0.9833 | 0.9694 | 0.0835 | 0.9508 | 0.9880 | 0.9710 | 0.0545 | 0.9589 | 0.9832 | 0.9666 | 0.0694 | 0.9511 | 0.9820 | 0.9681 | 0.0547 | 0.9559 | 0.9802 |
| dbCAN_4:HMMER | 0.9788 | 0.0520 | 0.9672 | 0.9903 | 0.8900 | 0.0819 | 0.8718 | 0.9082 | 0.9792 | 0.0447 | 0.9692 | 0.9891 | 0.9293 | 0.0648 | 0.9149 | 0.9438 | 0.9344 | 0.0483 | 0.9236 | 0.9451 |
The 95% CI was plotted as error bars around the mean CI (figure 4.1).
Figure 4.1: Summary statistics of CAZyme classifiers performances of binary CAZyme/non-CAZyme prediction. The mean plus and minus the 95% confidence interval.
4.2 Specificity
Specificity is the proportion of known negatives (known non-CAZymes) which are correctly classified as negatives (non-CAZymes). Figure 4.2 is a graphical representation of the results calculated in table 4.1.
Figure 4.2: One-dimensional scatter plot of specificity scores of CAZyme and non-CAZyme predictions per test set, overlaying box plot of standard deviation.
## Df Sum Sq Mean Sq F value Pr(>F)
## Prediction_tool 4 0.0227 0.005674 1.475 0.209
## Residuals 395 1.5199 0.003848Test for statistically significant differences between the main classifiers.
## Df Sum Sq Mean Sq F value Pr(>F)
## Prediction_tool 1 0.0152 0.01521 3.71 0.0559 .
## Residuals 158 0.6477 0.00410
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 14.3 Sensitivity
Sensitivity (also known as recall) is the proportion of known positives (CAZymes) that are correctly identified as positives (CAZymes). Figure 4.3 graphically represents of the results calculated in table 4.1.
Figure 4.3: One-dimensional scatter plot of recall (sensitivity) scores of CAZyme and non-CAZyme predictions per test set, overlaying box plot of standard deviation.
## Df Sum Sq Mean Sq F value Pr(>F)
## Prediction_tool 4 0.9811 0.24527 42.84 <2e-16 ***
## Residuals 395 2.2613 0.00572
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1Having found a statistically significant difference, use a Tukey HSD test to determine between which tools the means are significantly different.
## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistic_value ~ Prediction_tool, data = subset_sens.df)
##
## $Prediction_tool
## diff lwr upr p adj
## dbCAN_4:HMMER-dbCAN_4 -0.094125 -0.12690945 -0.06134055 0.0000000
## dbCAN_4:DIAMOND-dbCAN_4 -0.014750 -0.04753445 0.01803445 0.7321054
## dbCAN_4:dbCAN-sub-dbCAN_4 -0.034375 -0.06715945 -0.00159055 0.0345545
## CUPP-dbCAN_4 -0.130250 -0.16303445 -0.09746555 0.0000000
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.079375 0.04659055 0.11215945 0.0000000
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.059750 0.02696555 0.09253445 0.0000088
## CUPP-dbCAN_4:HMMER -0.036125 -0.06890945 -0.00334055 0.0224987
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND -0.019625 -0.05240945 0.01315945 0.4724309
## CUPP-dbCAN_4:DIAMOND -0.115500 -0.14828445 -0.08271555 0.0000000
## CUPP-dbCAN_4:dbCAN-sub -0.095875 -0.12865945 -0.06309055 0.0000000Test to see if the mean sensitivity is significantly different between the main classifiers.
## Df Sum Sq Mean Sq F value Pr(>F)
## Prediction_tool 1 0.6786 0.6786 140.9 <2e-16 ***
## Residuals 158 0.7610 0.0048
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1The means are statistically significantly different, therefore, use a post hoc Turkey HSD test to determine between which tools the means are significantly difference.
## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistic_value ~ Prediction_tool, data = subset_sens.df.main)
##
## $Prediction_tool
## diff lwr upr p adj
## CUPP-dbCAN_4 -0.13025 -0.1519236 -0.1085764 04.4 Precision
Precision is the proportion of positive predictions by the classifiers that are correct. In this case, precision represents the fraction of CAZyme predictions by the classifiers that are correct, specifically the proportion of predicted CAZymes that are known CAZymes. Figure 4.4 is a visual representation of the results calculated in table 4.1.
Figure 4.4: One-dimensional scatter plot of precision scores of CAZyme and non-CAZyme predictions per test set, overlaying box plot of standard deviation.
## Df Sum Sq Mean Sq F value Pr(>F)
## Prediction_tool 4 0.0119 0.002965 1.238 0.294
## Residuals 395 0.9463 0.002396## Df Sum Sq Mean Sq F value Pr(>F)
## Prediction_tool 1 0.0079 0.007851 3.057 0.0823 .
## Residuals 158 0.4058 0.002569
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 14.5 F1-score
The F1-score is a harmonic (or weighted) average of recall and precision and provides an idea of the overall performance of the tool, 0 being the lowest and 1 being the best performance. Figure 4.5 shows the F1-score from each test set, for each classifier.
Figure 4.5: Bar chart of specificity of CAZyme classifiers differentiation between CAZymes and non-CAZymes.
A one-way ANOVA was performed to determine if the mean F1-scores were statistically significantly different between the tools.
## Df Sum Sq Mean Sq F value Pr(>F)
## Prediction_tool 4 0.2316 0.05789 16.36 2.08e-12 ***
## Residuals 395 1.3980 0.00354
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1The means are statistically significantly different, therefore, use a post hoc Turkey HSD test to determine between which tools the means are significantly difference.
## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistic_value ~ Prediction_tool, data = subset_f1.df)
##
## $Prediction_tool
## diff lwr upr
## dbCAN_4:HMMER-dbCAN_4 -0.043910254 -0.069688290 -0.018132217
## dbCAN_4:DIAMOND-dbCAN_4 -0.006683100 -0.032461137 0.019094936
## dbCAN_4:dbCAN-sub-dbCAN_4 -0.011432464 -0.037210501 0.014345572
## CUPP-dbCAN_4 -0.062315777 -0.088093814 -0.036537741
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.037227154 0.011449117 0.063005190
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.032477790 0.006699753 0.058255826
## CUPP-dbCAN_4:HMMER -0.018405523 -0.044183560 0.007372513
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND -0.004749364 -0.030527400 0.021028673
## CUPP-dbCAN_4:DIAMOND -0.055632677 -0.081410713 -0.029854640
## CUPP-dbCAN_4:dbCAN-sub -0.050883313 -0.076661350 -0.025105277
## p adj
## dbCAN_4:HMMER-dbCAN_4 0.0000409
## dbCAN_4:DIAMOND-dbCAN_4 0.9540567
## dbCAN_4:dbCAN-sub-dbCAN_4 0.7424664
## CUPP-dbCAN_4 0.0000000
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.0008501
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.0055310
## CUPP-dbCAN_4:HMMER 0.2893896
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND 0.9868625
## CUPP-dbCAN_4:DIAMOND 0.0000001
## CUPP-dbCAN_4:dbCAN-sub 0.0000011A one-way ANOVA test was used to see if the mean F1-scores are significantly different between the main classifiers.
## Df Sum Sq Mean Sq F value Pr(>F)
## Prediction_tool 1 0.1553 0.15533 56.26 4.32e-12 ***
## Residuals 158 0.4363 0.00276
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1The means are statistically significantly different, therefore, use a post hoc Turkey HSD test to determine between which tools the means are significantly difference.
## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistic_value ~ Prediction_tool, data = subset_f1.df.main)
##
## $Prediction_tool
## diff lwr upr p adj
## CUPP-dbCAN_4 -0.06231578 -0.07872543 -0.04590612 04.6 Accuracy
Accuracy (calculated using (TP + TN) / (TP + TN + FP + FN) ) provides an idea of the overall performance of the classifiers as a measure of the degree to which their CAZyme/non-CAZyme predictions conforms to the correct result. Figure 4.6 is a plot of respective data from table 4.1.
Figure 4.6: Bar chart of specificity of CAZyme classifiers differentiation between CAZymes and non-CAZymes.
Test if the means are significantly different between the tools.
## Df Sum Sq Mean Sq F value Pr(>F)
## Prediction_tool 4 0.1856 0.04640 19.56 1.07e-14 ***
## Residuals 395 0.9370 0.00237
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1The means are statistically significantly different, therefore, use a post hoc Turkey HSD test to determine between which tools the means are significantly difference.
## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistic_value ~ Prediction_tool, data = subset_acc.df)
##
## $Prediction_tool
## diff lwr upr
## dbCAN_4:HMMER-dbCAN_4 -0.0388125 -0.059916719 -0.017708281
## dbCAN_4:DIAMOND-dbCAN_4 -0.0051250 -0.026229219 0.015979219
## dbCAN_4:dbCAN-sub-dbCAN_4 -0.0095625 -0.030666719 0.011541719
## CUPP-dbCAN_4 -0.0553750 -0.076479219 -0.034270781
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.0336875 0.012583281 0.054791719
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.0292500 0.008145781 0.050354219
## CUPP-dbCAN_4:HMMER -0.0165625 -0.037666719 0.004541719
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND -0.0044375 -0.025541719 0.016666719
## CUPP-dbCAN_4:DIAMOND -0.0502500 -0.071354219 -0.029145781
## CUPP-dbCAN_4:dbCAN-sub -0.0458125 -0.066916719 -0.024708281
## p adj
## dbCAN_4:HMMER-dbCAN_4 0.0000070
## dbCAN_4:DIAMOND-dbCAN_4 0.9636237
## dbCAN_4:dbCAN-sub-dbCAN_4 0.7268827
## CUPP-dbCAN_4 0.0000000
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.0001514
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.0015765
## CUPP-dbCAN_4:HMMER 0.2009823
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND 0.9784912
## CUPP-dbCAN_4:DIAMOND 0.0000000
## CUPP-dbCAN_4:dbCAN-sub 0.0000001Test if the means are significantly different between the main classifiers.
## Df Sum Sq Mean Sq F value Pr(>F)
## Prediction_tool 1 0.1227 0.12266 54.25 9.18e-12 ***
## Residuals 158 0.3572 0.00226
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1The means are statistically significantly different, therefore, use a post hoc Turkey HSD test to determine between which tools the means are significantly difference.
## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistic_value ~ Prediction_tool, data = subset_acc.df.main)
##
## $Prediction_tool
## diff lwr upr p adj
## CUPP-dbCAN_4 -0.055375 -0.07022366 -0.04052634 04.7 Combined statistics plot
Here we generate a plot that combines the plots from above into a single figure.
Figure 4.7: Box and whisker plots of the performance of CAZyme/non-CAZyme classification.
4.8 ROC curve - Receiver Operator Characteristic curve
The Receiver Operator Characteristic (ROC) curve, which enables us to compare sensitivity to specificity but plotting sensitivity versus 1-specificity.
## [1] 16000## [1] "CUPP ROC Curve (AUC = 0.9178)"## [1] "dbCAN_4 ROC Curve (AUC = 0.9732)"## [1] "dbCAN_4:HMMER ROC Curve (AUC = 0.9344)"## [1] "dbCAN_4:DIAMOND ROC Curve (AUC = 0.9681)"## [1] "dbCAN_4:dbCAN-sub ROC Curve (AUC = 0.9636)"
4.9 Expected Range of Accuracy
The statistics evaluated above provide an idea of the general performance of the tools, but they do not provide an idea of the expect range of performance. Specifically, the data does not provide a clear image of the best and worse performance a user can expect when using these tools.
To compare the expected typical range in accuracies for each classifier, 6 test sets (identified by the source genomic assemblies) were selected at random. The CAZyme/non-CAZyme predictions for each classifier, for each test set, were bootstrap resampled 100 times each, and for each bootstrap sample the accuracy calculated. The accuracies of the bootstrap samples for each classifier were plotted on stacked histograms, shown in figure 4.8.
Figure 4.8: Stacked histograms of bootstrap sample accuracies of CAZyme classifiers’ differentiation between CAZymes and non-CAZymes. 6 test sets (identified by their source genomic assembly) were selected at random. The CAZyme/non-CAZyme predictions for each classifier, for each test set, were bootstrap resampled 100 times. The accuracy of each of the 600 bootstrap samples per test set were plotted as a stacked histogram.
Plot as box and whisker plots.
4.10 Conclusions on the Binary CAZyme/non-CAZyme Prediction Performance
Overall, all tools showed a low probability of producing false positives (missclassifying a non-CAZyme as a CAZyme), and few of the positive predictions are false positives. Therefore, we can be confident in that the CAZyme predictions made by each of these tools are most likely correct. However, all the classifiers demonstrated a consistent behaviour to not identify all CAZymes within a CAZome. Therefore, we can be confident in the CAZyme predictions, but should not presume all non-CAZyme predictions are correct; these classifiers are unlikely to identify the complete CAZome although a near-complete CAZome will be accurately identified.
5 CAZyme/non-CAZyme classification: Taxonomic evaluation
The performance for a classifier per taxonomy group may vary. For this evaluation the test sets were separated into the taxonomy groups: - Bacteria - Eukaryote
The evaluation per classifier per taxonomy group, versus all test sets pooled together was evaluated.
5.1 Specificity
| Prediction_tool | Bact Mean | Bact Standard Deviation | Bact Lower CI | Bact Upper CI | Euk Mean | Euk Standard Deviation | Euk Lower CI | Euk Upper CI | All Mean | All Standard Deviation | All Lower CI | All Upper CI |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CUPP | 0.9888 | 0.0276 | 0.9799 | 0.9976 | 0.9748 | 0.0628 | 0.9547 | 0.9948 | 0.9818 | 0.0486 | 0.9742 | 0.9893 |
| dbCAN_4 | 0.9740 | 0.0383 | 0.9618 | 0.9862 | 0.9505 | 0.1003 | 0.9184 | 0.9826 | 0.9622 | 0.0761 | 0.9504 | 0.9741 |
| dbCAN_4:DIAMOND | 0.9798 | 0.0355 | 0.9684 | 0.9911 | 0.9538 | 0.0980 | 0.9224 | 0.9851 | 0.9668 | 0.0742 | 0.9552 | 0.9783 |
| dbCAN_4:HMMER | 0.9868 | 0.0284 | 0.9777 | 0.9958 | 0.9708 | 0.0673 | 0.9492 | 0.9923 | 0.9788 | 0.0518 | 0.9707 | 0.9868 |
| dbCAN_4:dbCAN-sub | 0.9868 | 0.0270 | 0.9781 | 0.9954 | 0.9682 | 0.0690 | 0.9462 | 0.9903 | 0.9775 | 0.0527 | 0.9693 | 0.9857 |
Test if there is a statistically significant difference between the means of the tools and kingdoms using a two-way ANOVA.
## Df Sum Sq Mean Sq F value Pr(>F)
## Tax_group 2 0.0384 0.019208 5.027 0.00677 **
## Prediction_tool 4 0.0454 0.011348 2.970 0.01885 *
## Tax_group:Prediction_tool 8 0.0020 0.000254 0.067 0.99983
## Residuals 785 2.9993 0.003821
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1Statistically significant difference was detected so follow up with a Tukey test to determine if there are differences between specific groups.
bin.tax.spec.tukey <- TukeyHSD(bin.tax.spec.2.aov, "Tax_group:Prediction_tool")
write.csv(
as.data.frame(bin.tax.spec.tukey$`Tax_group:Prediction_tool`),
"../report/cazyme_noncazyme_classification/tax_performance/binary.spec.classifiers.tukeyHSD.csv"
)
bin.tax.spec.tukey## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistic_value ~ Tax_group * Prediction_tool, data = binary_tax_df[binary_tax_df$Statistic_parameter == "Specificity", ])
##
## $`Tax_group:Prediction_tool`
## diff
## Bacteria:CUPP-All:CUPP 7.000000e-03
## Eukaryote:CUPP-All:CUPP -7.000000e-03
## All:dbCAN_4-All:CUPP -1.950000e-02
## Bacteria:dbCAN_4-All:CUPP -7.750000e-03
## Eukaryote:dbCAN_4-All:CUPP -3.125000e-02
## All:dbCAN_4:dbCAN-sub-All:CUPP -4.250000e-03
## Bacteria:dbCAN_4:dbCAN-sub-All:CUPP 5.000000e-03
## Eukaryote:dbCAN_4:dbCAN-sub-All:CUPP -1.350000e-02
## All:dbCAN_4:DIAMOND-All:CUPP -1.500000e-02
## Bacteria:dbCAN_4:DIAMOND-All:CUPP -2.000000e-03
## Eukaryote:dbCAN_4:DIAMOND-All:CUPP -2.800000e-02
## All:dbCAN_4:HMMER-All:CUPP -3.000000e-03
## Bacteria:dbCAN_4:HMMER-All:CUPP 5.000000e-03
## Eukaryote:dbCAN_4:HMMER-All:CUPP -1.100000e-02
## Eukaryote:CUPP-Bacteria:CUPP -1.400000e-02
## All:dbCAN_4-Bacteria:CUPP -2.650000e-02
## Bacteria:dbCAN_4-Bacteria:CUPP -1.475000e-02
## Eukaryote:dbCAN_4-Bacteria:CUPP -3.825000e-02
## All:dbCAN_4:dbCAN-sub-Bacteria:CUPP -1.125000e-02
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:CUPP -2.000000e-03
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:CUPP -2.050000e-02
## All:dbCAN_4:DIAMOND-Bacteria:CUPP -2.200000e-02
## Bacteria:dbCAN_4:DIAMOND-Bacteria:CUPP -9.000000e-03
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:CUPP -3.500000e-02
## All:dbCAN_4:HMMER-Bacteria:CUPP -1.000000e-02
## Bacteria:dbCAN_4:HMMER-Bacteria:CUPP -2.000000e-03
## Eukaryote:dbCAN_4:HMMER-Bacteria:CUPP -1.800000e-02
## All:dbCAN_4-Eukaryote:CUPP -1.250000e-02
## Bacteria:dbCAN_4-Eukaryote:CUPP -7.500000e-04
## Eukaryote:dbCAN_4-Eukaryote:CUPP -2.425000e-02
## All:dbCAN_4:dbCAN-sub-Eukaryote:CUPP 2.750000e-03
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:CUPP 1.200000e-02
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:CUPP -6.500000e-03
## All:dbCAN_4:DIAMOND-Eukaryote:CUPP -8.000000e-03
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:CUPP 5.000000e-03
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:CUPP -2.100000e-02
## All:dbCAN_4:HMMER-Eukaryote:CUPP 4.000000e-03
## Bacteria:dbCAN_4:HMMER-Eukaryote:CUPP 1.200000e-02
## Eukaryote:dbCAN_4:HMMER-Eukaryote:CUPP -4.000000e-03
## Bacteria:dbCAN_4-All:dbCAN_4 1.175000e-02
## Eukaryote:dbCAN_4-All:dbCAN_4 -1.175000e-02
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4 1.525000e-02
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4 2.450000e-02
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4 6.000000e-03
## All:dbCAN_4:DIAMOND-All:dbCAN_4 4.500000e-03
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4 1.750000e-02
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4 -8.500000e-03
## All:dbCAN_4:HMMER-All:dbCAN_4 1.650000e-02
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4 2.450000e-02
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4 8.500000e-03
## Eukaryote:dbCAN_4-Bacteria:dbCAN_4 -2.350000e-02
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 3.500000e-03
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 1.275000e-02
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 -5.750000e-03
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 -7.250000e-03
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 5.750000e-03
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 -2.025000e-02
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4 4.750000e-03
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4 1.275000e-02
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4 -3.250000e-03
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 2.700000e-02
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 3.625000e-02
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 1.775000e-02
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 1.625000e-02
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 2.925000e-02
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 3.250000e-03
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4 2.825000e-02
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4 3.625000e-02
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4 2.025000e-02
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub 9.250000e-03
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub -9.250000e-03
## All:dbCAN_4:DIAMOND-All:dbCAN_4:dbCAN-sub -1.075000e-02
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:dbCAN-sub 2.250000e-03
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:dbCAN-sub -2.375000e-02
## All:dbCAN_4:HMMER-All:dbCAN_4:dbCAN-sub 1.250000e-03
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:dbCAN-sub 9.250000e-03
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:dbCAN-sub -6.750000e-03
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:dbCAN-sub -1.850000e-02
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:dbCAN-sub -2.000000e-02
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:dbCAN-sub -7.000000e-03
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:dbCAN-sub -3.300000e-02
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4:dbCAN-sub -8.000000e-03
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4:dbCAN-sub 4.773959e-15
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:dbCAN-sub -1.600000e-02
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:dbCAN-sub -1.500000e-03
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:dbCAN-sub 1.150000e-02
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:dbCAN-sub -1.450000e-02
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4:dbCAN-sub 1.050000e-02
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4:dbCAN-sub 1.850000e-02
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4:dbCAN-sub 2.500000e-03
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND 1.300000e-02
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND -1.300000e-02
## All:dbCAN_4:HMMER-All:dbCAN_4:DIAMOND 1.200000e-02
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:DIAMOND 2.000000e-02
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:DIAMOND 4.000000e-03
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:DIAMOND -2.600000e-02
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4:DIAMOND -1.000000e-03
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4:DIAMOND 7.000000e-03
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:DIAMOND -9.000000e-03
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4:DIAMOND 2.500000e-02
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4:DIAMOND 3.300000e-02
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4:DIAMOND 1.700000e-02
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:HMMER 8.000000e-03
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:HMMER -8.000000e-03
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:HMMER -1.600000e-02
## lwr upr
## Bacteria:CUPP-All:CUPP -0.03372403 0.047724030
## Eukaryote:CUPP-All:CUPP -0.04772403 0.033724030
## All:dbCAN_4-All:CUPP -0.05275103 0.013751031
## Bacteria:dbCAN_4-All:CUPP -0.04847403 0.032974030
## Eukaryote:dbCAN_4-All:CUPP -0.07197403 0.009474030
## All:dbCAN_4:dbCAN-sub-All:CUPP -0.03750103 0.029001031
## Bacteria:dbCAN_4:dbCAN-sub-All:CUPP -0.03572403 0.045724030
## Eukaryote:dbCAN_4:dbCAN-sub-All:CUPP -0.05422403 0.027224030
## All:dbCAN_4:DIAMOND-All:CUPP -0.04825103 0.018251031
## Bacteria:dbCAN_4:DIAMOND-All:CUPP -0.04272403 0.038724030
## Eukaryote:dbCAN_4:DIAMOND-All:CUPP -0.06872403 0.012724030
## All:dbCAN_4:HMMER-All:CUPP -0.03625103 0.030251031
## Bacteria:dbCAN_4:HMMER-All:CUPP -0.03572403 0.045724030
## Eukaryote:dbCAN_4:HMMER-All:CUPP -0.05172403 0.029724030
## Eukaryote:CUPP-Bacteria:CUPP -0.06102406 0.033024059
## All:dbCAN_4-Bacteria:CUPP -0.06722403 0.014224030
## Bacteria:dbCAN_4-Bacteria:CUPP -0.06177406 0.032274059
## Eukaryote:dbCAN_4-Bacteria:CUPP -0.08527406 0.008774059
## All:dbCAN_4:dbCAN-sub-Bacteria:CUPP -0.05197403 0.029474030
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:CUPP -0.04902406 0.045024059
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:CUPP -0.06752406 0.026524059
## All:dbCAN_4:DIAMOND-Bacteria:CUPP -0.06272403 0.018724030
## Bacteria:dbCAN_4:DIAMOND-Bacteria:CUPP -0.05602406 0.038024059
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:CUPP -0.08202406 0.012024059
## All:dbCAN_4:HMMER-Bacteria:CUPP -0.05072403 0.030724030
## Bacteria:dbCAN_4:HMMER-Bacteria:CUPP -0.04902406 0.045024059
## Eukaryote:dbCAN_4:HMMER-Bacteria:CUPP -0.06502406 0.029024059
## All:dbCAN_4-Eukaryote:CUPP -0.05322403 0.028224030
## Bacteria:dbCAN_4-Eukaryote:CUPP -0.04777406 0.046274059
## Eukaryote:dbCAN_4-Eukaryote:CUPP -0.07127406 0.022774059
## All:dbCAN_4:dbCAN-sub-Eukaryote:CUPP -0.03797403 0.043474030
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:CUPP -0.03502406 0.059024059
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:CUPP -0.05352406 0.040524059
## All:dbCAN_4:DIAMOND-Eukaryote:CUPP -0.04872403 0.032724030
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:CUPP -0.04202406 0.052024059
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:CUPP -0.06802406 0.026024059
## All:dbCAN_4:HMMER-Eukaryote:CUPP -0.03672403 0.044724030
## Bacteria:dbCAN_4:HMMER-Eukaryote:CUPP -0.03502406 0.059024059
## Eukaryote:dbCAN_4:HMMER-Eukaryote:CUPP -0.05102406 0.043024059
## Bacteria:dbCAN_4-All:dbCAN_4 -0.02897403 0.052474030
## Eukaryote:dbCAN_4-All:dbCAN_4 -0.05247403 0.028974030
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4 -0.01800103 0.048501031
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4 -0.01622403 0.065224030
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4 -0.03472403 0.046724030
## All:dbCAN_4:DIAMOND-All:dbCAN_4 -0.02875103 0.037751031
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4 -0.02322403 0.058224030
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4 -0.04922403 0.032224030
## All:dbCAN_4:HMMER-All:dbCAN_4 -0.01675103 0.049751031
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4 -0.01622403 0.065224030
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4 -0.03222403 0.049224030
## Eukaryote:dbCAN_4-Bacteria:dbCAN_4 -0.07052406 0.023524059
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 -0.03722403 0.044224030
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 -0.03427406 0.059774059
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 -0.05277406 0.041274059
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 -0.04797403 0.033474030
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 -0.04127406 0.052774059
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 -0.06727406 0.026774059
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4 -0.03597403 0.045474030
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4 -0.03427406 0.059774059
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4 -0.05027406 0.043774059
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 -0.01372403 0.067724030
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 -0.01077406 0.083274059
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 -0.02927406 0.064774059
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 -0.02447403 0.056974030
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 -0.01777406 0.076274059
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 -0.04377406 0.050274059
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -0.01247403 0.068974030
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -0.01077406 0.083274059
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -0.02677406 0.067274059
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub -0.03147403 0.049974030
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub -0.04997403 0.031474030
## All:dbCAN_4:DIAMOND-All:dbCAN_4:dbCAN-sub -0.04400103 0.022501031
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:dbCAN-sub -0.03847403 0.042974030
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:dbCAN-sub -0.06447403 0.016974030
## All:dbCAN_4:HMMER-All:dbCAN_4:dbCAN-sub -0.03200103 0.034501031
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:dbCAN-sub -0.03147403 0.049974030
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:dbCAN-sub -0.04747403 0.033974030
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:dbCAN-sub -0.06552406 0.028524059
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:dbCAN-sub -0.06072403 0.020724030
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:dbCAN-sub -0.05402406 0.040024059
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:dbCAN-sub -0.08002406 0.014024059
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4:dbCAN-sub -0.04872403 0.032724030
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4:dbCAN-sub -0.04702406 0.047024059
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:dbCAN-sub -0.06302406 0.031024059
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:dbCAN-sub -0.04222403 0.039224030
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:dbCAN-sub -0.03552406 0.058524059
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:dbCAN-sub -0.06152406 0.032524059
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4:dbCAN-sub -0.03022403 0.051224030
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4:dbCAN-sub -0.02852406 0.065524059
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4:dbCAN-sub -0.04452406 0.049524059
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND -0.02772403 0.053724030
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND -0.05372403 0.027724030
## All:dbCAN_4:HMMER-All:dbCAN_4:DIAMOND -0.02125103 0.045251031
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:DIAMOND -0.02072403 0.060724030
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:DIAMOND -0.03672403 0.044724030
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:DIAMOND -0.07302406 0.021024059
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4:DIAMOND -0.04172403 0.039724030
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4:DIAMOND -0.04002406 0.054024059
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:DIAMOND -0.05602406 0.038024059
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4:DIAMOND -0.01572403 0.065724030
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4:DIAMOND -0.01402406 0.080024059
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4:DIAMOND -0.03002406 0.064024059
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:HMMER -0.03272403 0.048724030
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:HMMER -0.04872403 0.032724030
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:HMMER -0.06302406 0.031024059
## p adj
## Bacteria:CUPP-All:CUPP 0.9999995
## Eukaryote:CUPP-All:CUPP 0.9999995
## All:dbCAN_4-All:CUPP 0.8009444
## Bacteria:dbCAN_4-All:CUPP 0.9999982
## Eukaryote:dbCAN_4-All:CUPP 0.3641338
## All:dbCAN_4:dbCAN-sub-All:CUPP 1.0000000
## Bacteria:dbCAN_4:dbCAN-sub-All:CUPP 1.0000000
## Eukaryote:dbCAN_4:dbCAN-sub-All:CUPP 0.9985854
## All:dbCAN_4:DIAMOND-All:CUPP 0.9708111
## Bacteria:dbCAN_4:DIAMOND-All:CUPP 1.0000000
## Eukaryote:dbCAN_4:DIAMOND-All:CUPP 0.5613201
## All:dbCAN_4:HMMER-All:CUPP 1.0000000
## Bacteria:dbCAN_4:HMMER-All:CUPP 1.0000000
## Eukaryote:dbCAN_4:HMMER-All:CUPP 0.9998627
## Eukaryote:CUPP-Bacteria:CUPP 0.9995734
## All:dbCAN_4-Bacteria:CUPP 0.6547605
## Bacteria:dbCAN_4-Bacteria:CUPP 0.9992307
## Eukaryote:dbCAN_4-Bacteria:CUPP 0.2669272
## All:dbCAN_4:dbCAN-sub-Bacteria:CUPP 0.9998209
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:CUPP 1.0000000
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:CUPP 0.9783739
## All:dbCAN_4:DIAMOND-Bacteria:CUPP 0.8819957
## Bacteria:dbCAN_4:DIAMOND-Bacteria:CUPP 0.9999981
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:CUPP 0.4184121
## All:dbCAN_4:HMMER-Bacteria:CUPP 0.9999564
## Bacteria:dbCAN_4:HMMER-Bacteria:CUPP 1.0000000
## Eukaryote:dbCAN_4:HMMER-Bacteria:CUPP 0.9936682
## All:dbCAN_4-Eukaryote:CUPP 0.9993968
## Bacteria:dbCAN_4-Eukaryote:CUPP 1.0000000
## Eukaryote:dbCAN_4-Eukaryote:CUPP 0.9150509
## All:dbCAN_4:dbCAN-sub-Eukaryote:CUPP 1.0000000
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:CUPP 0.9999304
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:CUPP 1.0000000
## All:dbCAN_4:DIAMOND-Eukaryote:CUPP 0.9999973
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:CUPP 1.0000000
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:CUPP 0.9732568
## All:dbCAN_4:HMMER-Eukaryote:CUPP 1.0000000
## Bacteria:dbCAN_4:HMMER-Eukaryote:CUPP 0.9999304
## Eukaryote:dbCAN_4:HMMER-Eukaryote:CUPP 1.0000000
## Bacteria:dbCAN_4-All:dbCAN_4 0.9997026
## Eukaryote:dbCAN_4-All:dbCAN_4 0.9997026
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4 0.9663842
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4 0.7694409
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4 0.9999999
## All:dbCAN_4:DIAMOND-All:dbCAN_4 1.0000000
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4 0.9809940
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4 0.9999942
## All:dbCAN_4:HMMER-All:dbCAN_4 0.9363891
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4 0.7694409
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4 0.9999942
## Eukaryote:dbCAN_4-Bacteria:dbCAN_4 0.9328430
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 1.0000000
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 0.9998564
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 1.0000000
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 0.9999993
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 1.0000000
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 0.9806279
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4 1.0000000
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4 0.9998564
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4 1.0000000
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 0.6239911
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 0.3561385
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 0.9944939
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 0.9904892
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 0.7238142
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 1.0000000
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4 0.5455652
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4 0.3561385
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4 0.9806279
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub 0.9999833
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub 0.9999833
## All:dbCAN_4:DIAMOND-All:dbCAN_4:dbCAN-sub 0.9989244
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:dbCAN-sub 1.0000000
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:dbCAN-sub 0.8074114
## All:dbCAN_4:HMMER-All:dbCAN_4:dbCAN-sub 1.0000000
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:dbCAN-sub 0.9999833
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:dbCAN-sub 0.9999997
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:dbCAN-sub 0.9917086
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:dbCAN-sub 0.9413055
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:dbCAN-sub 0.9999999
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:dbCAN-sub 0.5248690
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4:dbCAN-sub 0.9999973
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4:dbCAN-sub 1.0000000
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:dbCAN-sub 0.9981262
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:dbCAN-sub 1.0000000
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:dbCAN-sub 0.9999585
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:dbCAN-sub 0.9993649
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4:dbCAN-sub 0.9999212
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4:dbCAN-sub 0.9917086
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4:dbCAN-sub 1.0000000
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND 0.9990649
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND 0.9990649
## All:dbCAN_4:HMMER-All:dbCAN_4:DIAMOND 0.9965162
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:DIAMOND 0.9413055
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:DIAMOND 1.0000000
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:DIAMOND 0.8621478
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4:DIAMOND 1.0000000
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4:DIAMOND 0.9999999
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:DIAMOND 0.9999981
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4:DIAMOND 0.7424011
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4:DIAMOND 0.5248690
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4:DIAMOND 0.9964532
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:HMMER 0.9999973
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:HMMER 0.9999973
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:HMMER 0.99812625.2 Sensitivity
| Prediction_tool | Bact Mean | Bact Standard Deviation | Bact Lower CI | Bact Upper CI | Euk Mean | Euk Standard Deviation | Euk Lower CI | Euk Upper CI | All Mean | All Standard Deviation | All Lower CI | All Upper CI |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CUPP | 0.8618 | 0.0788 | 0.8366 | 0.8869 | 0.8460 | 0.0699 | 0.8236 | 0.8684 | 0.8539 | 0.0742 | 0.8423 | 0.8655 |
| dbCAN_4 | 0.9748 | 0.0897 | 0.9461 | 1.0034 | 0.9935 | 0.0083 | 0.9908 | 0.9962 | 0.9841 | 0.0638 | 0.9742 | 0.9941 |
| dbCAN_4:DIAMOND | 0.9498 | 0.1149 | 0.9130 | 0.9865 | 0.9890 | 0.0110 | 0.9855 | 0.9925 | 0.9694 | 0.0832 | 0.9564 | 0.9824 |
| dbCAN_4:HMMER | 0.8765 | 0.1097 | 0.8414 | 0.9116 | 0.9035 | 0.0342 | 0.8926 | 0.9144 | 0.8900 | 0.0816 | 0.8773 | 0.9027 |
| dbCAN_4:dbCAN-sub | 0.9520 | 0.1011 | 0.9197 | 0.9843 | 0.9475 | 0.0228 | 0.9402 | 0.9548 | 0.9498 | 0.0726 | 0.9384 | 0.9611 |
Test if there is a statistically significant difference between the means of the tools and kingdoms using a two-way ANOVA.
## Df Sum Sq Mean Sq F value Pr(>F)
## Tax_group 2 0.017 0.0084 1.474 0.230
## Prediction_tool 4 1.962 0.4905 86.245 <2e-16 ***
## Tax_group:Prediction_tool 8 0.041 0.0051 0.901 0.515
## Residuals 785 4.465 0.0057
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1Statistically significant difference was detected so follow up with a Tukey test to determine if there are differences between specific groups.
bin.tax.sens.tukey <- TukeyHSD(bin.tax.sens.2.aov, "Tax_group:Prediction_tool")
write.csv(
as.data.frame(bin.tax.sens.tukey$`Tax_group:Prediction_tool`),
"../report/cazyme_noncazyme_classification/tax_performance/binary.sens.classifiers.tukeyHSD.csv"
)
bin.tax.sens.tukey## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistic_value ~ Tax_group * Prediction_tool, data = binary_tax_df[binary_tax_df$Statistic_parameter == "Sensitivity", ])
##
## $`Tax_group:Prediction_tool`
## diff
## Bacteria:CUPP-All:CUPP 7.875000e-03
## Eukaryote:CUPP-All:CUPP -7.875000e-03
## All:dbCAN_4-All:CUPP 1.302500e-01
## Bacteria:dbCAN_4-All:CUPP 1.208750e-01
## Eukaryote:dbCAN_4-All:CUPP 1.396250e-01
## All:dbCAN_4:dbCAN-sub-All:CUPP 9.587500e-02
## Bacteria:dbCAN_4:dbCAN-sub-All:CUPP 9.812500e-02
## Eukaryote:dbCAN_4:dbCAN-sub-All:CUPP 9.362500e-02
## All:dbCAN_4:DIAMOND-All:CUPP 1.155000e-01
## Bacteria:dbCAN_4:DIAMOND-All:CUPP 9.587500e-02
## Eukaryote:dbCAN_4:DIAMOND-All:CUPP 1.351250e-01
## All:dbCAN_4:HMMER-All:CUPP 3.612500e-02
## Bacteria:dbCAN_4:HMMER-All:CUPP 2.262500e-02
## Eukaryote:dbCAN_4:HMMER-All:CUPP 4.962500e-02
## Eukaryote:CUPP-Bacteria:CUPP -1.575000e-02
## All:dbCAN_4-Bacteria:CUPP 1.223750e-01
## Bacteria:dbCAN_4-Bacteria:CUPP 1.130000e-01
## Eukaryote:dbCAN_4-Bacteria:CUPP 1.317500e-01
## All:dbCAN_4:dbCAN-sub-Bacteria:CUPP 8.800000e-02
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:CUPP 9.025000e-02
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:CUPP 8.575000e-02
## All:dbCAN_4:DIAMOND-Bacteria:CUPP 1.076250e-01
## Bacteria:dbCAN_4:DIAMOND-Bacteria:CUPP 8.800000e-02
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:CUPP 1.272500e-01
## All:dbCAN_4:HMMER-Bacteria:CUPP 2.825000e-02
## Bacteria:dbCAN_4:HMMER-Bacteria:CUPP 1.475000e-02
## Eukaryote:dbCAN_4:HMMER-Bacteria:CUPP 4.175000e-02
## All:dbCAN_4-Eukaryote:CUPP 1.381250e-01
## Bacteria:dbCAN_4-Eukaryote:CUPP 1.287500e-01
## Eukaryote:dbCAN_4-Eukaryote:CUPP 1.475000e-01
## All:dbCAN_4:dbCAN-sub-Eukaryote:CUPP 1.037500e-01
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:CUPP 1.060000e-01
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:CUPP 1.015000e-01
## All:dbCAN_4:DIAMOND-Eukaryote:CUPP 1.233750e-01
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:CUPP 1.037500e-01
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:CUPP 1.430000e-01
## All:dbCAN_4:HMMER-Eukaryote:CUPP 4.400000e-02
## Bacteria:dbCAN_4:HMMER-Eukaryote:CUPP 3.050000e-02
## Eukaryote:dbCAN_4:HMMER-Eukaryote:CUPP 5.750000e-02
## Bacteria:dbCAN_4-All:dbCAN_4 -9.375000e-03
## Eukaryote:dbCAN_4-All:dbCAN_4 9.375000e-03
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4 -3.437500e-02
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4 -3.212500e-02
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4 -3.662500e-02
## All:dbCAN_4:DIAMOND-All:dbCAN_4 -1.475000e-02
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4 -3.437500e-02
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4 4.875000e-03
## All:dbCAN_4:HMMER-All:dbCAN_4 -9.412500e-02
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4 -1.076250e-01
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4 -8.062500e-02
## Eukaryote:dbCAN_4-Bacteria:dbCAN_4 1.875000e-02
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 -2.500000e-02
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 -2.275000e-02
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 -2.725000e-02
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 -5.375000e-03
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 -2.500000e-02
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 1.425000e-02
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4 -8.475000e-02
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4 -9.825000e-02
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4 -7.125000e-02
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 -4.375000e-02
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 -4.150000e-02
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 -4.600000e-02
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 -2.412500e-02
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 -4.375000e-02
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 -4.500000e-03
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -1.035000e-01
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -1.170000e-01
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -9.000000e-02
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub 2.250000e-03
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub -2.250000e-03
## All:dbCAN_4:DIAMOND-All:dbCAN_4:dbCAN-sub 1.962500e-02
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:dbCAN-sub -4.440892e-16
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:dbCAN-sub 3.925000e-02
## All:dbCAN_4:HMMER-All:dbCAN_4:dbCAN-sub -5.975000e-02
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:dbCAN-sub -7.325000e-02
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:dbCAN-sub -4.625000e-02
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:dbCAN-sub -4.500000e-03
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:dbCAN-sub 1.737500e-02
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:dbCAN-sub -2.250000e-03
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:dbCAN-sub 3.700000e-02
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4:dbCAN-sub -6.200000e-02
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4:dbCAN-sub -7.550000e-02
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:dbCAN-sub -4.850000e-02
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:dbCAN-sub 2.187500e-02
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:dbCAN-sub 2.250000e-03
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:dbCAN-sub 4.150000e-02
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4:dbCAN-sub -5.750000e-02
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4:dbCAN-sub -7.100000e-02
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4:dbCAN-sub -4.400000e-02
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND -1.962500e-02
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND 1.962500e-02
## All:dbCAN_4:HMMER-All:dbCAN_4:DIAMOND -7.937500e-02
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:DIAMOND -9.287500e-02
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:DIAMOND -6.587500e-02
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:DIAMOND 3.925000e-02
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4:DIAMOND -5.975000e-02
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4:DIAMOND -7.325000e-02
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:DIAMOND -4.625000e-02
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4:DIAMOND -9.900000e-02
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4:DIAMOND -1.125000e-01
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4:DIAMOND -8.550000e-02
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:HMMER -1.350000e-02
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:HMMER 1.350000e-02
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:HMMER 2.700000e-02
## lwr
## Bacteria:CUPP-All:CUPP -4.181188e-02
## Eukaryote:CUPP-All:CUPP -5.756188e-02
## All:dbCAN_4-All:CUPP 8.968083e-02
## Bacteria:dbCAN_4-All:CUPP 7.118812e-02
## Eukaryote:dbCAN_4-All:CUPP 8.993812e-02
## All:dbCAN_4:dbCAN-sub-All:CUPP 5.530583e-02
## Bacteria:dbCAN_4:dbCAN-sub-All:CUPP 4.843812e-02
## Eukaryote:dbCAN_4:dbCAN-sub-All:CUPP 4.393812e-02
## All:dbCAN_4:DIAMOND-All:CUPP 7.493083e-02
## Bacteria:dbCAN_4:DIAMOND-All:CUPP 4.618812e-02
## Eukaryote:dbCAN_4:DIAMOND-All:CUPP 8.543812e-02
## All:dbCAN_4:HMMER-All:CUPP -4.444169e-03
## Bacteria:dbCAN_4:HMMER-All:CUPP -2.706188e-02
## Eukaryote:dbCAN_4:HMMER-All:CUPP -6.188143e-05
## Eukaryote:CUPP-Bacteria:CUPP -7.312347e-02
## All:dbCAN_4-Bacteria:CUPP 7.268812e-02
## Bacteria:dbCAN_4-Bacteria:CUPP 5.562653e-02
## Eukaryote:dbCAN_4-Bacteria:CUPP 7.437653e-02
## All:dbCAN_4:dbCAN-sub-Bacteria:CUPP 3.831312e-02
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:CUPP 3.287653e-02
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:CUPP 2.837653e-02
## All:dbCAN_4:DIAMOND-Bacteria:CUPP 5.793812e-02
## Bacteria:dbCAN_4:DIAMOND-Bacteria:CUPP 3.062653e-02
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:CUPP 6.987653e-02
## All:dbCAN_4:HMMER-Bacteria:CUPP -2.143688e-02
## Bacteria:dbCAN_4:HMMER-Bacteria:CUPP -4.262347e-02
## Eukaryote:dbCAN_4:HMMER-Bacteria:CUPP -1.562347e-02
## All:dbCAN_4-Eukaryote:CUPP 8.843812e-02
## Bacteria:dbCAN_4-Eukaryote:CUPP 7.137653e-02
## Eukaryote:dbCAN_4-Eukaryote:CUPP 9.012653e-02
## All:dbCAN_4:dbCAN-sub-Eukaryote:CUPP 5.406312e-02
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:CUPP 4.862653e-02
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:CUPP 4.412653e-02
## All:dbCAN_4:DIAMOND-Eukaryote:CUPP 7.368812e-02
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:CUPP 4.637653e-02
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:CUPP 8.562653e-02
## All:dbCAN_4:HMMER-Eukaryote:CUPP -5.686881e-03
## Bacteria:dbCAN_4:HMMER-Eukaryote:CUPP -2.687347e-02
## Eukaryote:dbCAN_4:HMMER-Eukaryote:CUPP 1.265313e-04
## Bacteria:dbCAN_4-All:dbCAN_4 -5.906188e-02
## Eukaryote:dbCAN_4-All:dbCAN_4 -4.031188e-02
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4 -7.494417e-02
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4 -8.181188e-02
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4 -8.631188e-02
## All:dbCAN_4:DIAMOND-All:dbCAN_4 -5.531917e-02
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4 -8.406188e-02
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4 -4.481188e-02
## All:dbCAN_4:HMMER-All:dbCAN_4 -1.346942e-01
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4 -1.573119e-01
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4 -1.303119e-01
## Eukaryote:dbCAN_4-Bacteria:dbCAN_4 -3.862347e-02
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 -7.468688e-02
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 -8.012347e-02
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 -8.462347e-02
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 -5.506188e-02
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 -8.237347e-02
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 -4.312347e-02
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4 -1.344369e-01
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4 -1.556235e-01
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4 -1.286235e-01
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 -9.343688e-02
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 -9.887347e-02
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 -1.033735e-01
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 -7.381188e-02
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 -1.011235e-01
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 -6.187347e-02
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -1.531869e-01
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -1.743735e-01
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -1.473735e-01
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub -4.743688e-02
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub -5.193688e-02
## All:dbCAN_4:DIAMOND-All:dbCAN_4:dbCAN-sub -2.094417e-02
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:dbCAN-sub -4.968688e-02
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:dbCAN-sub -1.043688e-02
## All:dbCAN_4:HMMER-All:dbCAN_4:dbCAN-sub -1.003192e-01
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:dbCAN-sub -1.229369e-01
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:dbCAN-sub -9.593688e-02
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:dbCAN-sub -6.187347e-02
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:dbCAN-sub -3.231188e-02
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:dbCAN-sub -5.962347e-02
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:dbCAN-sub -2.037347e-02
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4:dbCAN-sub -1.116869e-01
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4:dbCAN-sub -1.328735e-01
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:dbCAN-sub -1.058735e-01
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:dbCAN-sub -2.781188e-02
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:dbCAN-sub -5.512347e-02
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:dbCAN-sub -1.587347e-02
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4:dbCAN-sub -1.071869e-01
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4:dbCAN-sub -1.283735e-01
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4:dbCAN-sub -1.013735e-01
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND -6.931188e-02
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND -3.006188e-02
## All:dbCAN_4:HMMER-All:dbCAN_4:DIAMOND -1.199442e-01
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:DIAMOND -1.425619e-01
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:DIAMOND -1.155619e-01
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:DIAMOND -1.812347e-02
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4:DIAMOND -1.094369e-01
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4:DIAMOND -1.306235e-01
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:DIAMOND -1.036235e-01
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4:DIAMOND -1.486869e-01
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4:DIAMOND -1.698735e-01
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4:DIAMOND -1.428735e-01
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:HMMER -6.318688e-02
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:HMMER -3.618688e-02
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:HMMER -3.037347e-02
## upr p adj
## Bacteria:CUPP-All:CUPP 0.057561881 0.9999998
## Eukaryote:CUPP-All:CUPP 0.041811881 0.9999998
## All:dbCAN_4-All:CUPP 0.170819169 0.0000000
## Bacteria:dbCAN_4-All:CUPP 0.170561881 0.0000000
## Eukaryote:dbCAN_4-All:CUPP 0.189311881 0.0000000
## All:dbCAN_4:dbCAN-sub-All:CUPP 0.136444169 0.0000000
## Bacteria:dbCAN_4:dbCAN-sub-All:CUPP 0.147811881 0.0000000
## Eukaryote:dbCAN_4:dbCAN-sub-All:CUPP 0.143311881 0.0000000
## All:dbCAN_4:DIAMOND-All:CUPP 0.156069169 0.0000000
## Bacteria:dbCAN_4:DIAMOND-All:CUPP 0.145561881 0.0000000
## Eukaryote:dbCAN_4:DIAMOND-All:CUPP 0.184811881 0.0000000
## All:dbCAN_4:HMMER-All:CUPP 0.076694169 0.1444525
## Bacteria:dbCAN_4:HMMER-All:CUPP 0.072311881 0.9683743
## Eukaryote:dbCAN_4:HMMER-All:CUPP 0.099311881 0.0506652
## Eukaryote:CUPP-Bacteria:CUPP 0.041623469 0.9998337
## All:dbCAN_4-Bacteria:CUPP 0.172061881 0.0000000
## Bacteria:dbCAN_4-Bacteria:CUPP 0.170373469 0.0000000
## Eukaryote:dbCAN_4-Bacteria:CUPP 0.189123469 0.0000000
## All:dbCAN_4:dbCAN-sub-Bacteria:CUPP 0.137686881 0.0000003
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:CUPP 0.147623469 0.0000117
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:CUPP 0.143123469 0.0000467
## All:dbCAN_4:DIAMOND-Bacteria:CUPP 0.157311881 0.0000000
## Bacteria:dbCAN_4:DIAMOND-Bacteria:CUPP 0.145373469 0.0000236
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:CUPP 0.184623469 0.0000000
## All:dbCAN_4:HMMER-Bacteria:CUPP 0.077936881 0.8351191
## Bacteria:dbCAN_4:HMMER-Bacteria:CUPP 0.072123469 0.9999239
## Eukaryote:dbCAN_4:HMMER-Bacteria:CUPP 0.099123469 0.4592481
## All:dbCAN_4-Eukaryote:CUPP 0.187811881 0.0000000
## Bacteria:dbCAN_4-Eukaryote:CUPP 0.186123469 0.0000000
## Eukaryote:dbCAN_4-Eukaryote:CUPP 0.204873469 0.0000000
## All:dbCAN_4:dbCAN-sub-Eukaryote:CUPP 0.153436881 0.0000000
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:CUPP 0.163373469 0.0000000
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:CUPP 0.158873469 0.0000003
## All:dbCAN_4:DIAMOND-Eukaryote:CUPP 0.173061881 0.0000000
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:CUPP 0.161123469 0.0000001
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:CUPP 0.200373469 0.0000000
## All:dbCAN_4:HMMER-Eukaryote:CUPP 0.093686881 0.1507267
## Bacteria:dbCAN_4:HMMER-Eukaryote:CUPP 0.087873469 0.8944066
## Eukaryote:dbCAN_4:HMMER-Eukaryote:CUPP 0.114873469 0.0488403
## Bacteria:dbCAN_4-All:dbCAN_4 0.040311881 0.9999984
## Eukaryote:dbCAN_4-All:dbCAN_4 0.059061881 0.9999984
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4 0.006194169 0.2066351
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4 0.017561881 0.6650797
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4 0.013061881 0.4359196
## All:dbCAN_4:DIAMOND-All:dbCAN_4 0.025819169 0.9962392
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4 0.015311881 0.5503411
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4 0.054561881 1.0000000
## All:dbCAN_4:HMMER-All:dbCAN_4 -0.053555831 0.0000000
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4 -0.057938119 0.0000000
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4 -0.030938119 0.0000047
## Eukaryote:dbCAN_4-Bacteria:dbCAN_4 0.076123469 0.9987891
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 0.024686881 0.9292812
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 0.034623469 0.9910499
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 0.030123469 0.9550521
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 0.044311881 1.0000000
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 0.032373469 0.9784647
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 0.071623469 0.9999499
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4 -0.035063119 0.0000010
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4 -0.040876531 0.0000009
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4 -0.013876531 0.0024616
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 0.005936881 0.1573668
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 0.015873469 0.4701474
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 0.011373469 0.2899279
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 0.025561881 0.9463458
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 0.013623469 0.3751934
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 0.052873469 1.0000000
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -0.053813119 0.0000000
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -0.059626531 0.0000000
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -0.032626531 0.0000127
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub 0.051936881 1.0000000
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub 0.047436881 1.0000000
## All:dbCAN_4:DIAMOND-All:dbCAN_4:dbCAN-sub 0.060194169 0.9479052
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:dbCAN-sub 0.049686881 1.0000000
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:dbCAN-sub 0.088936881 0.3143981
## All:dbCAN_4:HMMER-All:dbCAN_4:dbCAN-sub -0.019180831 0.0000677
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:dbCAN-sub -0.023563119 0.0000661
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:dbCAN-sub 0.003436881 0.1001306
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:dbCAN-sub 0.052873469 1.0000000
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:dbCAN-sub 0.067061881 0.9974937
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:dbCAN-sub 0.055123469 1.0000000
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:dbCAN-sub 0.094373469 0.6691417
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4:dbCAN-sub -0.012313119 0.0022624
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4:dbCAN-sub -0.018126531 0.0008339
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:dbCAN-sub 0.008873469 0.2098783
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:dbCAN-sub 0.071561881 0.9764007
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:dbCAN-sub 0.059623469 1.0000000
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:dbCAN-sub 0.098873469 0.4701474
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4:dbCAN-sub -0.007813119 0.0077651
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4:dbCAN-sub -0.013626531 0.0026177
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4:dbCAN-sub 0.013373469 0.3651734
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND 0.030061881 0.9913837
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND 0.069311881 0.9913837
## All:dbCAN_4:HMMER-All:dbCAN_4:DIAMOND -0.038805831 0.0000000
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:DIAMOND -0.043188119 0.0000000
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:DIAMOND -0.016188119 0.0007182
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:DIAMOND 0.096623469 0.5701476
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4:DIAMOND -0.010063119 0.0042495
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4:DIAMOND -0.015876531 0.0014919
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:DIAMOND 0.011123469 0.2811915
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4:DIAMOND -0.049313119 0.0000000
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4:DIAMOND -0.055126531 0.0000000
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4:DIAMOND -0.028126531 0.0000503
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:HMMER 0.036186881 0.9998528
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:HMMER 0.063186881 0.9998528
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:HMMER 0.084373469 0.95831805.3 Precision
| Prediction_tool | Bact Mean | Bact Standard Deviation | Bact Lower CI | Bact Upper CI | Euk Mean | Euk Standard Deviation | Euk Lower CI | Euk Upper CI | All Mean | All Standard Deviation | All Lower CI | All Upper CI |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CUPP | 0.9877 | 0.0280 | 0.9787 | 0.9966 | 0.9748 | 0.0574 | 0.9564 | 0.9932 | 0.9812 | 0.0452 | 0.9742 | 0.9883 |
| dbCAN_4 | 0.9755 | 0.0346 | 0.9645 | 0.9866 | 0.9589 | 0.0700 | 0.9365 | 0.9813 | 0.9672 | 0.0553 | 0.9586 | 0.9759 |
| dbCAN_4:DIAMOND | 0.9805 | 0.0327 | 0.9701 | 0.9910 | 0.9615 | 0.0690 | 0.9394 | 0.9836 | 0.9710 | 0.0544 | 0.9625 | 0.9795 |
| dbCAN_4:HMMER | 0.9858 | 0.0297 | 0.9763 | 0.9953 | 0.9725 | 0.0556 | 0.9548 | 0.9903 | 0.9792 | 0.0446 | 0.9722 | 0.9861 |
| dbCAN_4:dbCAN-sub | 0.9869 | 0.0258 | 0.9786 | 0.9951 | 0.9715 | 0.0547 | 0.9540 | 0.9889 | 0.9792 | 0.0431 | 0.9724 | 0.9859 |
Test if there is a statistically significant difference between the means of the tools and kingdoms using a two-way ANOVA.
## Df Sum Sq Mean Sq F value Pr(>F)
## Tax_group 2 0.0239 0.011932 5.013 0.00686 **
## Prediction_tool 4 0.0237 0.005931 2.492 0.04184 *
## Tax_group:Prediction_tool 8 0.0005 0.000064 0.027 0.99999
## Residuals 785 1.8683 0.002380
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1Statistically significant difference was detected so follow up with a Tukey test to determine if there are differences between groups.
bin.tax.prec.tukey <- TukeyHSD(bin.tax.prec.2.aov, "Tax_group:Prediction_tool")
write.csv(
as.data.frame(bin.tax.prec.tukey$`Tax_group:Prediction_tool`),
"../report/cazyme_noncazyme_classification/tax_performance/binary.prec.classifiers.tukeyHSD.csv"
)
bin.tax.prec.tukey## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistic_value ~ Tax_group * Prediction_tool, data = binary_tax_df[binary_tax_df$Statistic_parameter == "Precision", ])
##
## $`Tax_group:Prediction_tool`
## diff
## Bacteria:CUPP-All:CUPP 6.442536e-03
## Eukaryote:CUPP-All:CUPP -6.442536e-03
## All:dbCAN_4-All:CUPP -1.401012e-02
## Bacteria:dbCAN_4-All:CUPP -5.695376e-03
## Eukaryote:dbCAN_4-All:CUPP -2.232486e-02
## All:dbCAN_4:dbCAN-sub-All:CUPP -2.075279e-03
## Bacteria:dbCAN_4:dbCAN-sub-All:CUPP 5.640131e-03
## Eukaryote:dbCAN_4:dbCAN-sub-All:CUPP -9.790689e-03
## All:dbCAN_4:DIAMOND-All:CUPP -1.022395e-02
## Bacteria:dbCAN_4:DIAMOND-All:CUPP -7.147117e-04
## Eukaryote:dbCAN_4:DIAMOND-All:CUPP -1.973319e-02
## All:dbCAN_4:HMMER-All:CUPP -2.078097e-03
## Bacteria:dbCAN_4:HMMER-All:CUPP 4.559742e-03
## Eukaryote:dbCAN_4:HMMER-All:CUPP -8.715937e-03
## Eukaryote:CUPP-Bacteria:CUPP -1.288507e-02
## All:dbCAN_4-Bacteria:CUPP -2.045265e-02
## Bacteria:dbCAN_4-Bacteria:CUPP -1.213791e-02
## Eukaryote:dbCAN_4-Bacteria:CUPP -2.876739e-02
## All:dbCAN_4:dbCAN-sub-Bacteria:CUPP -8.517815e-03
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:CUPP -8.024053e-04
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:CUPP -1.623323e-02
## All:dbCAN_4:DIAMOND-Bacteria:CUPP -1.666649e-02
## Bacteria:dbCAN_4:DIAMOND-Bacteria:CUPP -7.157248e-03
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:CUPP -2.617572e-02
## All:dbCAN_4:HMMER-Bacteria:CUPP -8.520633e-03
## Bacteria:dbCAN_4:HMMER-Bacteria:CUPP -1.882794e-03
## Eukaryote:dbCAN_4:HMMER-Bacteria:CUPP -1.515847e-02
## All:dbCAN_4-Eukaryote:CUPP -7.567581e-03
## Bacteria:dbCAN_4-Eukaryote:CUPP 7.471596e-04
## Eukaryote:dbCAN_4-Eukaryote:CUPP -1.588232e-02
## All:dbCAN_4:dbCAN-sub-Eukaryote:CUPP 4.367257e-03
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:CUPP 1.208267e-02
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:CUPP -3.348153e-03
## All:dbCAN_4:DIAMOND-Eukaryote:CUPP -3.781414e-03
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:CUPP 5.727824e-03
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:CUPP -1.329065e-02
## All:dbCAN_4:HMMER-Eukaryote:CUPP 4.364439e-03
## Bacteria:dbCAN_4:HMMER-Eukaryote:CUPP 1.100228e-02
## Eukaryote:dbCAN_4:HMMER-Eukaryote:CUPP -2.273401e-03
## Bacteria:dbCAN_4-All:dbCAN_4 8.314741e-03
## Eukaryote:dbCAN_4-All:dbCAN_4 -8.314741e-03
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4 1.193484e-02
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4 1.965025e-02
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4 4.219428e-03
## All:dbCAN_4:DIAMOND-All:dbCAN_4 3.786167e-03
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4 1.329541e-02
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4 -5.723071e-03
## All:dbCAN_4:HMMER-All:dbCAN_4 1.193202e-02
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4 1.856986e-02
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4 5.294180e-03
## Eukaryote:dbCAN_4-Bacteria:dbCAN_4 -1.662948e-02
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 3.620097e-03
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 1.133551e-02
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 -4.095313e-03
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 -4.528573e-03
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 4.980665e-03
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 -1.403781e-02
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4 3.617279e-03
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4 1.025512e-02
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4 -3.020560e-03
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 2.024958e-02
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 2.796499e-02
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 1.253417e-02
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 1.210091e-02
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 2.161015e-02
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 2.591670e-03
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4 2.024676e-02
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4 2.688460e-02
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4 1.360892e-02
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub 7.715410e-03
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub -7.715410e-03
## All:dbCAN_4:DIAMOND-All:dbCAN_4:dbCAN-sub -8.148670e-03
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:dbCAN-sub 1.360568e-03
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:dbCAN-sub -1.765791e-02
## All:dbCAN_4:HMMER-All:dbCAN_4:dbCAN-sub -2.817948e-06
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:dbCAN-sub 6.635021e-03
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:dbCAN-sub -6.640657e-03
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:dbCAN-sub -1.543082e-02
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:dbCAN-sub -1.586408e-02
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:dbCAN-sub -6.354842e-03
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:dbCAN-sub -2.537332e-02
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4:dbCAN-sub -7.718228e-03
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4:dbCAN-sub -1.080389e-03
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:dbCAN-sub -1.435607e-02
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:dbCAN-sub -4.332605e-04
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:dbCAN-sub 9.075978e-03
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:dbCAN-sub -9.942498e-03
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4:dbCAN-sub 7.712592e-03
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4:dbCAN-sub 1.435043e-02
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4:dbCAN-sub 1.074753e-03
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND 9.509238e-03
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND -9.509238e-03
## All:dbCAN_4:HMMER-All:dbCAN_4:DIAMOND 8.145853e-03
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:DIAMOND 1.478369e-02
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:DIAMOND 1.508013e-03
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:DIAMOND -1.901848e-02
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4:DIAMOND -1.363385e-03
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4:DIAMOND 5.274454e-03
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:DIAMOND -8.001225e-03
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4:DIAMOND 1.765509e-02
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4:DIAMOND 2.429293e-02
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4:DIAMOND 1.101725e-02
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:HMMER 6.637839e-03
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:HMMER -6.637839e-03
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:HMMER -1.327568e-02
## lwr upr
## Bacteria:CUPP-All:CUPP -0.025698666 0.038583738
## Eukaryote:CUPP-All:CUPP -0.038583738 0.025698666
## All:dbCAN_4-All:CUPP -0.040253299 0.012233065
## Bacteria:dbCAN_4-All:CUPP -0.037836579 0.026445826
## Eukaryote:dbCAN_4-All:CUPP -0.054466060 0.009816345
## All:dbCAN_4:dbCAN-sub-All:CUPP -0.028318461 0.024167903
## Bacteria:dbCAN_4:dbCAN-sub-All:CUPP -0.026501072 0.037781333
## Eukaryote:dbCAN_4:dbCAN-sub-All:CUPP -0.041931892 0.022350513
## All:dbCAN_4:DIAMOND-All:CUPP -0.036467131 0.016019232
## Bacteria:dbCAN_4:DIAMOND-All:CUPP -0.032855914 0.031426491
## Eukaryote:dbCAN_4:DIAMOND-All:CUPP -0.051874390 0.012408015
## All:dbCAN_4:HMMER-All:CUPP -0.028321279 0.024165085
## Bacteria:dbCAN_4:HMMER-All:CUPP -0.027581460 0.036700944
## Eukaryote:dbCAN_4:HMMER-All:CUPP -0.040857139 0.023425266
## Eukaryote:CUPP-Bacteria:CUPP -0.049998536 0.024228392
## All:dbCAN_4-Bacteria:CUPP -0.052593855 0.011688549
## Bacteria:dbCAN_4-Bacteria:CUPP -0.049251376 0.024975551
## Eukaryote:dbCAN_4-Bacteria:CUPP -0.065880857 0.008346070
## All:dbCAN_4:dbCAN-sub-Bacteria:CUPP -0.040659018 0.023623387
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:CUPP -0.037915869 0.036311058
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:CUPP -0.053346689 0.020880238
## All:dbCAN_4:DIAMOND-Bacteria:CUPP -0.048807688 0.015474717
## Bacteria:dbCAN_4:DIAMOND-Bacteria:CUPP -0.044270711 0.029956216
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:CUPP -0.063289187 0.010937740
## All:dbCAN_4:HMMER-Bacteria:CUPP -0.040661835 0.023620569
## Bacteria:dbCAN_4:HMMER-Bacteria:CUPP -0.038996257 0.035230670
## Eukaryote:dbCAN_4:HMMER-Bacteria:CUPP -0.052271936 0.021954991
## All:dbCAN_4-Eukaryote:CUPP -0.039708783 0.024573621
## Bacteria:dbCAN_4-Eukaryote:CUPP -0.036366304 0.037860623
## Eukaryote:dbCAN_4-Eukaryote:CUPP -0.052995785 0.021231142
## All:dbCAN_4:dbCAN-sub-Eukaryote:CUPP -0.027773946 0.036508459
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:CUPP -0.025030797 0.049196130
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:CUPP -0.040461617 0.033765310
## All:dbCAN_4:DIAMOND-Eukaryote:CUPP -0.035922616 0.028359789
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:CUPP -0.031385639 0.042841288
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:CUPP -0.050404115 0.023822812
## All:dbCAN_4:HMMER-Eukaryote:CUPP -0.027776764 0.036505641
## Bacteria:dbCAN_4:HMMER-Eukaryote:CUPP -0.026111185 0.048115742
## Eukaryote:dbCAN_4:HMMER-Eukaryote:CUPP -0.039386864 0.034840063
## Bacteria:dbCAN_4-All:dbCAN_4 -0.023826462 0.040455943
## Eukaryote:dbCAN_4-All:dbCAN_4 -0.040455943 0.023826462
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4 -0.014308344 0.038178019
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4 -0.012490955 0.051791450
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4 -0.027921775 0.036360630
## All:dbCAN_4:DIAMOND-All:dbCAN_4 -0.022457015 0.030029349
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4 -0.018845797 0.045436608
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4 -0.037864273 0.026418132
## All:dbCAN_4:HMMER-All:dbCAN_4 -0.014311162 0.038175202
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4 -0.013571343 0.050711061
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4 -0.026847022 0.037435383
## Eukaryote:dbCAN_4-Bacteria:dbCAN_4 -0.053742945 0.020483982
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 -0.028521105 0.035761299
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 -0.025777956 0.048448971
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 -0.041208776 0.033018151
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 -0.036669776 0.027612629
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 -0.032132799 0.042094128
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 -0.051151275 0.023075652
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4 -0.028523923 0.035758481
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4 -0.026858345 0.047368582
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4 -0.040134024 0.034092903
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 -0.011891624 0.052390781
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 -0.009148475 0.065078452
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 -0.024579295 0.049647632
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 -0.020040294 0.044242110
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 -0.015503318 0.058723609
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 -0.034521794 0.039705133
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -0.011894442 0.052387963
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -0.010228864 0.063998063
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -0.023504543 0.050722385
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub -0.024425792 0.039856612
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub -0.039856612 0.024425792
## All:dbCAN_4:DIAMOND-All:dbCAN_4:dbCAN-sub -0.034391852 0.018094511
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:dbCAN-sub -0.030780635 0.033501770
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:dbCAN-sub -0.049799111 0.014483294
## All:dbCAN_4:HMMER-All:dbCAN_4:dbCAN-sub -0.026246000 0.026240364
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:dbCAN-sub -0.025506181 0.038776224
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:dbCAN-sub -0.038781860 0.025500545
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:dbCAN-sub -0.052544284 0.021682644
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:dbCAN-sub -0.048005283 0.016277122
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:dbCAN-sub -0.043468306 0.030758621
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:dbCAN-sub -0.062486782 0.011740145
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4:dbCAN-sub -0.039859430 0.024422974
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4:dbCAN-sub -0.038193852 0.036033075
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:dbCAN-sub -0.051469531 0.022757396
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:dbCAN-sub -0.032574463 0.031707942
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:dbCAN-sub -0.028037486 0.046189441
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:dbCAN-sub -0.047055962 0.027170965
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4:dbCAN-sub -0.024428610 0.039853794
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4:dbCAN-sub -0.022763032 0.051463895
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4:dbCAN-sub -0.036038711 0.038188216
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND -0.022631964 0.041650440
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND -0.041650440 0.022631964
## All:dbCAN_4:HMMER-All:dbCAN_4:DIAMOND -0.018097329 0.034389034
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:DIAMOND -0.017357510 0.046924894
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:DIAMOND -0.030633189 0.033649215
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:DIAMOND -0.056131940 0.018094988
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4:DIAMOND -0.033504588 0.030777817
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4:DIAMOND -0.031839010 0.042387917
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:DIAMOND -0.045114688 0.029112239
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4:DIAMOND -0.014486112 0.049796293
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4:DIAMOND -0.012820534 0.061406393
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4:DIAMOND -0.026096212 0.048130715
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:HMMER -0.025503363 0.038779042
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:HMMER -0.038779042 0.025503363
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:HMMER -0.050389142 0.023837785
## p adj
## Bacteria:CUPP-All:CUPP 0.9999966
## Eukaryote:CUPP-All:CUPP 0.9999966
## All:dbCAN_4-All:CUPP 0.8912457
## Bacteria:dbCAN_4-All:CUPP 0.9999993
## Eukaryote:dbCAN_4-All:CUPP 0.5432734
## All:dbCAN_4:dbCAN-sub-All:CUPP 1.0000000
## Bacteria:dbCAN_4:dbCAN-sub-All:CUPP 0.9999994
## Eukaryote:dbCAN_4:dbCAN-sub-All:CUPP 0.9994465
## All:dbCAN_4:DIAMOND-All:CUPP 0.9924650
## Bacteria:dbCAN_4:DIAMOND-All:CUPP 1.0000000
## Eukaryote:dbCAN_4:DIAMOND-All:CUPP 0.7422550
## All:dbCAN_4:HMMER-All:CUPP 1.0000000
## Bacteria:dbCAN_4:HMMER-All:CUPP 1.0000000
## Eukaryote:dbCAN_4:HMMER-All:CUPP 0.9998561
## Eukaryote:CUPP-Bacteria:CUPP 0.9976774
## All:dbCAN_4-Bacteria:CUPP 0.6899689
## Bacteria:dbCAN_4-Bacteria:CUPP 0.9987792
## Eukaryote:dbCAN_4-Bacteria:CUPP 0.3466304
## All:dbCAN_4:dbCAN-sub-Bacteria:CUPP 0.9998905
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:CUPP 1.0000000
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:CUPP 0.9777261
## All:dbCAN_4:DIAMOND-Bacteria:CUPP 0.9115731
## Bacteria:dbCAN_4:DIAMOND-Bacteria:CUPP 0.9999979
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:CUPP 0.5158675
## All:dbCAN_4:HMMER-Bacteria:CUPP 0.9998901
## Bacteria:dbCAN_4:HMMER-Bacteria:CUPP 1.0000000
## Eukaryote:dbCAN_4:HMMER-Bacteria:CUPP 0.9881200
## All:dbCAN_4-Eukaryote:CUPP 0.9999740
## Bacteria:dbCAN_4-Eukaryote:CUPP 1.0000000
## Eukaryote:dbCAN_4-Eukaryote:CUPP 0.9816961
## All:dbCAN_4:dbCAN-sub-Eukaryote:CUPP 1.0000000
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:CUPP 0.9988387
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:CUPP 1.0000000
## All:dbCAN_4:DIAMOND-Eukaryote:CUPP 1.0000000
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:CUPP 0.9999999
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:CUPP 0.9967849
## All:dbCAN_4:HMMER-Eukaryote:CUPP 1.0000000
## Bacteria:dbCAN_4:HMMER-Eukaryote:CUPP 0.9995937
## Eukaryote:dbCAN_4:HMMER-Eukaryote:CUPP 1.0000000
## Bacteria:dbCAN_4-All:dbCAN_4 0.9999180
## Eukaryote:dbCAN_4-All:dbCAN_4 0.9999180
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4 0.9687125
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4 0.7480448
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4 1.0000000
## All:dbCAN_4:DIAMOND-All:dbCAN_4 1.0000000
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4 0.9866130
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4 0.9999993
## All:dbCAN_4:HMMER-All:dbCAN_4 0.9687756
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4 0.8179686
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4 0.9999997
## Eukaryote:dbCAN_4-Bacteria:dbCAN_4 0.9724703
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 1.0000000
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 0.9994296
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 1.0000000
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 1.0000000
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 1.0000000
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 0.9943796
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4 1.0000000
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4 0.9998204
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4 1.0000000
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 0.7050715
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 0.3963812
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 0.9982702
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 0.9946350
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 0.8092227
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 1.0000000
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4 0.7052794
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4 0.4674935
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4 0.9958958
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub 0.9999670
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub 0.9999670
## All:dbCAN_4:DIAMOND-All:dbCAN_4:dbCAN-sub 0.9993132
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:dbCAN-sub 1.0000000
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:dbCAN-sub 0.8678466
## All:dbCAN_4:HMMER-All:dbCAN_4:dbCAN-sub 1.0000000
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:dbCAN-sub 0.9999950
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:dbCAN-sub 0.9999949
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:dbCAN-sub 0.9859595
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:dbCAN-sub 0.9389718
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:dbCAN-sub 0.9999996
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:dbCAN-sub 0.5712896
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4:dbCAN-sub 0.9999668
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4:dbCAN-sub 1.0000000
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:dbCAN-sub 0.9929757
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:dbCAN-sub 1.0000000
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:dbCAN-sub 0.9999585
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:dbCAN-sub 0.9998755
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4:dbCAN-sub 0.9999671
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4:dbCAN-sub 0.9930029
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4:dbCAN-sub 1.0000000
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND 0.9996029
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND 0.9996029
## All:dbCAN_4:HMMER-All:dbCAN_4:DIAMOND 0.9993159
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:DIAMOND 0.9655520
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:DIAMOND 1.0000000
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:DIAMOND 0.9189113
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4:DIAMOND 1.0000000
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4:DIAMOND 1.0000000
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:DIAMOND 0.9999913
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4:DIAMOND 0.8679866
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4:DIAMOND 0.6452048
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4:DIAMOND 0.9995874
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:HMMER 0.9999950
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:HMMER 0.9999950
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:HMMER 0.99682235.4 F1-score
| Prediction_tool | Bact Mean | Bact Standard Deviation | Bact Lower CI | Bact Upper CI | Euk Mean | Euk Standard Deviation | Euk Lower CI | Euk Upper CI | All Mean | All Standard Deviation | All Lower CI | All Upper CI |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CUPP | 0.9184 | 0.0518 | 0.9018 | 0.9349 | 0.9035 | 0.0519 | 0.8869 | 0.9201 | 0.9109 | 0.0519 | 0.9028 | 0.9190 |
| dbCAN_4 | 0.9720 | 0.0627 | 0.9519 | 0.9920 | 0.9745 | 0.0421 | 0.9611 | 0.9880 | 0.9733 | 0.0529 | 0.9650 | 0.9815 |
| dbCAN_4:DIAMOND | 0.9594 | 0.0890 | 0.9310 | 0.9879 | 0.9737 | 0.0415 | 0.9604 | 0.9870 | 0.9666 | 0.0691 | 0.9558 | 0.9774 |
| dbCAN_4:HMMER | 0.9231 | 0.0851 | 0.8959 | 0.9503 | 0.9356 | 0.0343 | 0.9246 | 0.9465 | 0.9293 | 0.0646 | 0.9193 | 0.9394 |
| dbCAN_4:dbCAN-sub | 0.9654 | 0.0738 | 0.9418 | 0.9889 | 0.9583 | 0.0308 | 0.9484 | 0.9682 | 0.9618 | 0.0561 | 0.9531 | 0.9706 |
Test if there is a statistically significant difference between the means of the tools and kingdoms using a two-way ANOVA.
## Df Sum Sq Mean Sq F value Pr(>F)
## Tax_group 2 0.0002 0.00011 0.031 0.969
## Prediction_tool 4 0.4631 0.11578 32.654 <2e-16 ***
## Tax_group:Prediction_tool 8 0.0125 0.00156 0.441 0.897
## Residuals 785 2.7834 0.00355
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1Statistically significant difference was detected so follow up with a Tukey test to determine if there are differences between groups.
bin.tax.f1.tukey <- TukeyHSD(bin.tax.f1.2.aov, "Tax_group:Prediction_tool")
write.csv(
as.data.frame(bin.tax.f1.tukey$`Tax_group:Prediction_tool`),
"../report/cazyme_noncazyme_classification/tax_performance/binary.f1.classifiers.tukeyHSD.csv"
)
bin.tax.f1.tukey## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistic_value ~ Tax_group * Prediction_tool, data = binary_tax_df[binary_tax_df$Statistic_parameter == "F1-score", ])
##
## $`Tax_group:Prediction_tool`
## diff
## Bacteria:CUPP-All:CUPP 0.0074145405
## Eukaryote:CUPP-All:CUPP -0.0074145405
## All:dbCAN_4-All:CUPP 0.0623157773
## Bacteria:dbCAN_4-All:CUPP 0.0610461947
## Eukaryote:dbCAN_4-All:CUPP 0.0635853598
## All:dbCAN_4:dbCAN-sub-All:CUPP 0.0508833132
## Bacteria:dbCAN_4:dbCAN-sub-All:CUPP 0.0544114807
## Eukaryote:dbCAN_4:dbCAN-sub-All:CUPP 0.0473551456
## All:dbCAN_4:DIAMOND-All:CUPP 0.0556326769
## Bacteria:dbCAN_4:DIAMOND-All:CUPP 0.0484835034
## Eukaryote:dbCAN_4:DIAMOND-All:CUPP 0.0627818503
## All:dbCAN_4:HMMER-All:CUPP 0.0184055233
## Bacteria:dbCAN_4:HMMER-All:CUPP 0.0121686933
## Eukaryote:dbCAN_4:HMMER-All:CUPP 0.0246423534
## Eukaryote:CUPP-Bacteria:CUPP -0.0148290811
## All:dbCAN_4-Bacteria:CUPP 0.0549012367
## Bacteria:dbCAN_4-Bacteria:CUPP 0.0536316542
## Eukaryote:dbCAN_4-Bacteria:CUPP 0.0561708193
## All:dbCAN_4:dbCAN-sub-Bacteria:CUPP 0.0434687726
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:CUPP 0.0469969402
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:CUPP 0.0399406051
## All:dbCAN_4:DIAMOND-Bacteria:CUPP 0.0482181363
## Bacteria:dbCAN_4:DIAMOND-Bacteria:CUPP 0.0410689629
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:CUPP 0.0553673098
## All:dbCAN_4:HMMER-Bacteria:CUPP 0.0109909828
## Bacteria:dbCAN_4:HMMER-Bacteria:CUPP 0.0047541527
## Eukaryote:dbCAN_4:HMMER-Bacteria:CUPP 0.0172278128
## All:dbCAN_4-Eukaryote:CUPP 0.0697303178
## Bacteria:dbCAN_4-Eukaryote:CUPP 0.0684607353
## Eukaryote:dbCAN_4-Eukaryote:CUPP 0.0709999003
## All:dbCAN_4:dbCAN-sub-Eukaryote:CUPP 0.0582978537
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:CUPP 0.0618260213
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:CUPP 0.0547696861
## All:dbCAN_4:DIAMOND-Eukaryote:CUPP 0.0630472174
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:CUPP 0.0558980439
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:CUPP 0.0701963909
## All:dbCAN_4:HMMER-Eukaryote:CUPP 0.0258200638
## Bacteria:dbCAN_4:HMMER-Eukaryote:CUPP 0.0195832338
## Eukaryote:dbCAN_4:HMMER-Eukaryote:CUPP 0.0320568939
## Bacteria:dbCAN_4-All:dbCAN_4 -0.0012695825
## Eukaryote:dbCAN_4-All:dbCAN_4 0.0012695825
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4 -0.0114324641
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4 -0.0079042965
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4 -0.0149606317
## All:dbCAN_4:DIAMOND-All:dbCAN_4 -0.0066831004
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4 -0.0138322739
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4 0.0004660731
## All:dbCAN_4:HMMER-All:dbCAN_4 -0.0439102540
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4 -0.0501470840
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4 -0.0376734239
## Eukaryote:dbCAN_4-Bacteria:dbCAN_4 0.0025391651
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 -0.0101628816
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 -0.0066347140
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 -0.0136910491
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 -0.0054135179
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 -0.0125626914
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 0.0017356556
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4 -0.0426406714
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4 -0.0488775015
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4 -0.0364038414
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 -0.0127020466
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 -0.0091738791
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 -0.0162302142
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 -0.0079526829
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 -0.0151018564
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 -0.0008035095
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -0.0451798365
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -0.0514166665
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -0.0389430064
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub 0.0035281676
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub -0.0035281676
## All:dbCAN_4:DIAMOND-All:dbCAN_4:dbCAN-sub 0.0047493637
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:dbCAN-sub -0.0023998098
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:dbCAN-sub 0.0118985372
## All:dbCAN_4:HMMER-All:dbCAN_4:dbCAN-sub -0.0324777899
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:dbCAN-sub -0.0387146199
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:dbCAN-sub -0.0262409598
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:dbCAN-sub -0.0070563351
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:dbCAN-sub 0.0012211961
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:dbCAN-sub -0.0059279773
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:dbCAN-sub 0.0083703696
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4:dbCAN-sub -0.0360059574
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4:dbCAN-sub -0.0422427875
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:dbCAN-sub -0.0297691274
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:dbCAN-sub 0.0082775313
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:dbCAN-sub 0.0011283578
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:dbCAN-sub 0.0154267047
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4:dbCAN-sub -0.0289496223
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4:dbCAN-sub -0.0351864523
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4:dbCAN-sub -0.0227127922
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND -0.0071491735
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND 0.0071491735
## All:dbCAN_4:HMMER-All:dbCAN_4:DIAMOND -0.0372271535
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:DIAMOND -0.0434639836
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:DIAMOND -0.0309903235
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:DIAMOND 0.0142983469
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4:DIAMOND -0.0300779801
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4:DIAMOND -0.0363148101
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:DIAMOND -0.0238411500
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4:DIAMOND -0.0443763270
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4:DIAMOND -0.0506131571
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4:DIAMOND -0.0381394970
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:HMMER -0.0062368300
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:HMMER 0.0062368300
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:HMMER 0.0124736601
## lwr
## Bacteria:CUPP-All:CUPP -0.031816139
## Eukaryote:CUPP-All:CUPP -0.046645220
## All:dbCAN_4-All:CUPP 0.030284061
## Bacteria:dbCAN_4-All:CUPP 0.021815515
## Eukaryote:dbCAN_4-All:CUPP 0.024354680
## All:dbCAN_4:dbCAN-sub-All:CUPP 0.018851597
## Bacteria:dbCAN_4:dbCAN-sub-All:CUPP 0.015180801
## Eukaryote:dbCAN_4:dbCAN-sub-All:CUPP 0.008124466
## All:dbCAN_4:DIAMOND-All:CUPP 0.023600961
## Bacteria:dbCAN_4:DIAMOND-All:CUPP 0.009252824
## Eukaryote:dbCAN_4:DIAMOND-All:CUPP 0.023551171
## All:dbCAN_4:HMMER-All:CUPP -0.013626193
## Bacteria:dbCAN_4:HMMER-All:CUPP -0.027061987
## Eukaryote:dbCAN_4:HMMER-All:CUPP -0.014588326
## Eukaryote:CUPP-Bacteria:CUPP -0.060128768
## All:dbCAN_4-Bacteria:CUPP 0.015670557
## Bacteria:dbCAN_4-Bacteria:CUPP 0.008331967
## Eukaryote:dbCAN_4-Bacteria:CUPP 0.010871132
## All:dbCAN_4:dbCAN-sub-Bacteria:CUPP 0.004238093
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:CUPP 0.001697253
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:CUPP -0.005359082
## All:dbCAN_4:DIAMOND-Bacteria:CUPP 0.008987457
## Bacteria:dbCAN_4:DIAMOND-Bacteria:CUPP -0.004230724
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:CUPP 0.010067623
## All:dbCAN_4:HMMER-Bacteria:CUPP -0.028239697
## Bacteria:dbCAN_4:HMMER-Bacteria:CUPP -0.040545534
## Eukaryote:dbCAN_4:HMMER-Bacteria:CUPP -0.028071874
## All:dbCAN_4-Eukaryote:CUPP 0.030499638
## Bacteria:dbCAN_4-Eukaryote:CUPP 0.023161048
## Eukaryote:dbCAN_4-Eukaryote:CUPP 0.025700213
## All:dbCAN_4:dbCAN-sub-Eukaryote:CUPP 0.019067174
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:CUPP 0.016526334
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:CUPP 0.009469999
## All:dbCAN_4:DIAMOND-Eukaryote:CUPP 0.023816538
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:CUPP 0.010598357
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:CUPP 0.024896704
## All:dbCAN_4:HMMER-Eukaryote:CUPP -0.013410616
## Bacteria:dbCAN_4:HMMER-Eukaryote:CUPP -0.025716453
## Eukaryote:dbCAN_4:HMMER-Eukaryote:CUPP -0.013242793
## Bacteria:dbCAN_4-All:dbCAN_4 -0.040500262
## Eukaryote:dbCAN_4-All:dbCAN_4 -0.037961097
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4 -0.043464180
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4 -0.047134976
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4 -0.054191311
## All:dbCAN_4:DIAMOND-All:dbCAN_4 -0.038714816
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4 -0.053062954
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4 -0.038764607
## All:dbCAN_4:HMMER-All:dbCAN_4 -0.075941970
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4 -0.089377764
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4 -0.076904104
## Eukaryote:dbCAN_4-Bacteria:dbCAN_4 -0.042760522
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 -0.049393561
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 -0.051934401
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 -0.058990736
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 -0.044644198
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 -0.057862378
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 -0.043564031
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4 -0.081871351
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4 -0.094177189
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4 -0.081703528
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 -0.051932726
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 -0.054473566
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 -0.061529901
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 -0.047183363
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 -0.060401543
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 -0.046103197
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -0.084410516
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -0.096716354
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -0.084242694
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub -0.035702512
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub -0.042758847
## All:dbCAN_4:DIAMOND-All:dbCAN_4:dbCAN-sub -0.027282352
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:dbCAN-sub -0.041630490
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:dbCAN-sub -0.027332143
## All:dbCAN_4:HMMER-All:dbCAN_4:dbCAN-sub -0.064509506
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:dbCAN-sub -0.077945300
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:dbCAN-sub -0.065471640
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:dbCAN-sub -0.052356022
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:dbCAN-sub -0.038009484
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:dbCAN-sub -0.051227664
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:dbCAN-sub -0.036929317
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4:dbCAN-sub -0.075236637
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4:dbCAN-sub -0.087542475
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:dbCAN-sub -0.075068814
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:dbCAN-sub -0.030953149
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:dbCAN-sub -0.044171329
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:dbCAN-sub -0.029872982
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4:dbCAN-sub -0.068180302
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4:dbCAN-sub -0.080486139
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4:dbCAN-sub -0.068012479
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND -0.046379853
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND -0.032081506
## All:dbCAN_4:HMMER-All:dbCAN_4:DIAMOND -0.069258869
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:DIAMOND -0.082694663
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:DIAMOND -0.070221003
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:DIAMOND -0.031001340
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4:DIAMOND -0.069308660
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4:DIAMOND -0.081614497
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:DIAMOND -0.069140837
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4:DIAMOND -0.083607007
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4:DIAMOND -0.095912844
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4:DIAMOND -0.083439184
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:HMMER -0.045467510
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:HMMER -0.032993850
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:HMMER -0.032826027
## upr p adj
## Bacteria:CUPP-All:CUPP 0.0466452203 0.9999984
## Eukaryote:CUPP-All:CUPP 0.0318161393 0.9999984
## All:dbCAN_4-All:CUPP 0.0943474932 0.0000000
## Bacteria:dbCAN_4-All:CUPP 0.1002768745 0.0000159
## Eukaryote:dbCAN_4-All:CUPP 0.1028160396 0.0000049
## All:dbCAN_4:dbCAN-sub-All:CUPP 0.0829150291 0.0000089
## Bacteria:dbCAN_4:dbCAN-sub-All:CUPP 0.0936421605 0.0002772
## Eukaryote:dbCAN_4:dbCAN-sub-All:CUPP 0.0865858254 0.0039928
## All:dbCAN_4:DIAMOND-All:CUPP 0.0876643928 0.0000005
## Bacteria:dbCAN_4:DIAMOND-All:CUPP 0.0877141832 0.0026791
## Eukaryote:dbCAN_4:DIAMOND-All:CUPP 0.1020125301 0.0000072
## All:dbCAN_4:HMMER-All:CUPP 0.0504372392 0.8239553
## Bacteria:dbCAN_4:HMMER-All:CUPP 0.0513993731 0.9993212
## Eukaryote:dbCAN_4:HMMER-All:CUPP 0.0638730332 0.7095154
## Eukaryote:CUPP-Bacteria:CUPP 0.0304706060 0.9987667
## All:dbCAN_4-Bacteria:CUPP 0.0941319165 0.0002270
## Bacteria:dbCAN_4-Bacteria:CUPP 0.0989313413 0.0054620
## Eukaryote:dbCAN_4-Bacteria:CUPP 0.1014705064 0.0025278
## All:dbCAN_4:dbCAN-sub-Bacteria:CUPP 0.0826994524 0.0144733
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:CUPP 0.0922966273 0.0332034
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:CUPP 0.0852402922 0.1557864
## All:dbCAN_4:DIAMOND-Bacteria:CUPP 0.0874488161 0.0029456
## Bacteria:dbCAN_4:DIAMOND-Bacteria:CUPP 0.0863686499 0.1251996
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:CUPP 0.1006669969 0.0032404
## All:dbCAN_4:HMMER-Bacteria:CUPP 0.0502216626 0.9997888
## Bacteria:dbCAN_4:HMMER-Bacteria:CUPP 0.0500538398 1.0000000
## Eukaryote:dbCAN_4:HMMER-Bacteria:CUPP 0.0625274999 0.9940645
## All:dbCAN_4-Eukaryote:CUPP 0.1089609976 0.0000002
## Bacteria:dbCAN_4-Eukaryote:CUPP 0.1137604224 0.0000350
## Eukaryote:dbCAN_4-Eukaryote:CUPP 0.1162995874 0.0000130
## All:dbCAN_4:dbCAN-sub-Eukaryote:CUPP 0.0975285335 0.0000541
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:CUPP 0.1071257084 0.0003933
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:CUPP 0.1000693732 0.0038872
## All:dbCAN_4:DIAMOND-Eukaryote:CUPP 0.1022778972 0.0000063
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:CUPP 0.1011977310 0.0027515
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:CUPP 0.1154960780 0.0000179
## All:dbCAN_4:HMMER-Eukaryote:CUPP 0.0650507436 0.6361833
## Bacteria:dbCAN_4:HMMER-Eukaryote:CUPP 0.0648829209 0.9799393
## Eukaryote:dbCAN_4:HMMER-Eukaryote:CUPP 0.0773565810 0.5098104
## Bacteria:dbCAN_4-All:dbCAN_4 0.0379610973 1.0000000
## Eukaryote:dbCAN_4-All:dbCAN_4 0.0405002623 1.0000000
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4 0.0205992518 0.9968950
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4 0.0313263833 0.9999963
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4 0.0242700481 0.9939001
## All:dbCAN_4:DIAMOND-All:dbCAN_4 0.0253486155 0.9999943
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4 0.0253984059 0.9972664
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4 0.0396967529 1.0000000
## All:dbCAN_4:HMMER-All:dbCAN_4 -0.0118785380 0.0003579
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4 -0.0109164042 0.0014588
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4 0.0015572559 0.0752306
## Eukaryote:dbCAN_4-Bacteria:dbCAN_4 0.0478388521 1.0000000
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 0.0290677982 0.9999166
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 0.0386649731 0.9999999
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 0.0316086380 0.9994936
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 0.0338171619 1.0000000
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 0.0327369957 0.9998126
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 0.0470353427 1.0000000
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4 -0.0034099916 0.0187011
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4 -0.0035778144 0.0205585
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4 0.0088958457 0.2861834
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 0.0265286332 0.9989067
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 0.0361258080 0.9999961
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 0.0290694729 0.9967683
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 0.0312779969 0.9999960
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 0.0301978307 0.9984961
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 0.0444961776 1.0000000
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -0.0059491567 0.0083499
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -0.0061169795 0.0103290
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4 0.0063566806 0.1871736
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub 0.0427588474 1.0000000
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub 0.0357025122 1.0000000
## All:dbCAN_4:DIAMOND-All:dbCAN_4:dbCAN-sub 0.0367810796 0.9999999
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:dbCAN-sub 0.0368308700 1.0000000
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:dbCAN-sub 0.0511292170 0.9994731
## All:dbCAN_4:HMMER-All:dbCAN_4:dbCAN-sub -0.0004460739 0.0430562
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:dbCAN-sub 0.0005160599 0.0574165
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:dbCAN-sub 0.0129897200 0.6090606
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:dbCAN-sub 0.0382433520 0.9999999
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:dbCAN-sub 0.0404518759 1.0000000
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:dbCAN-sub 0.0393717097 1.0000000
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:dbCAN-sub 0.0536700567 0.9999988
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4:dbCAN-sub 0.0032247224 0.1130648
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4:dbCAN-sub 0.0030568996 0.0985440
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:dbCAN-sub 0.0155305597 0.6386937
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:dbCAN-sub 0.0475082111 0.9999934
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:dbCAN-sub 0.0464280449 1.0000000
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:dbCAN-sub 0.0607263918 0.9981087
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4:dbCAN-sub 0.0102810575 0.4339158
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4:dbCAN-sub 0.0101132347 0.3430117
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4:dbCAN-sub 0.0225868948 0.9311386
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND 0.0320815063 0.9999990
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND 0.0463798533 0.9999990
## All:dbCAN_4:HMMER-All:dbCAN_4:DIAMOND -0.0051954376 0.0072799
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:DIAMOND -0.0042333038 0.0144950
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:DIAMOND 0.0082403563 0.3143890
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:DIAMOND 0.0595980340 0.9991751
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4:DIAMOND 0.0091526997 0.3656526
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4:DIAMOND 0.0089848770 0.2901451
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:DIAMOND 0.0214585371 0.9016178
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4:DIAMOND -0.0051456472 0.0108476
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4:DIAMOND -0.0053134700 0.0129066
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4:DIAMOND 0.0071601901 0.2155306
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:HMMER 0.0329938497 0.9999998
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:HMMER 0.0454675098 0.9999998
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:HMMER 0.0577733472 0.99982765.5 Accuracy
| Prediction_tool | Bact Mean | Bact Standard Deviation | Bact Lower CI | Bact Upper CI | Euk Mean | Euk Standard Deviation | Euk Lower CI | Euk Upper CI | All Mean | All Standard Deviation | All Lower CI | All Upper CI |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CUPP | 0.9252 | 0.0430 | 0.9115 | 0.9390 | 0.9104 | 0.0481 | 0.8950 | 0.9258 | 0.9178 | 0.0458 | 0.9107 | 0.9250 |
| dbCAN_4 | 0.9744 | 0.0474 | 0.9592 | 0.9895 | 0.9720 | 0.0513 | 0.9556 | 0.9884 | 0.9732 | 0.0489 | 0.9655 | 0.9808 |
| dbCAN_4:DIAMOND | 0.9648 | 0.0591 | 0.9459 | 0.9836 | 0.9714 | 0.0504 | 0.9552 | 0.9875 | 0.9681 | 0.0545 | 0.9596 | 0.9766 |
| dbCAN_4:HMMER | 0.9316 | 0.0574 | 0.9133 | 0.9500 | 0.9371 | 0.0375 | 0.9251 | 0.9491 | 0.9344 | 0.0481 | 0.9269 | 0.9419 |
| dbCAN_4:dbCAN-sub | 0.9694 | 0.0528 | 0.9525 | 0.9863 | 0.9579 | 0.0351 | 0.9466 | 0.9691 | 0.9636 | 0.0448 | 0.9566 | 0.9706 |
Test if there is a statistically significant difference between the means of the tools and kingdoms using a two-way ANOVA.
## Df Sum Sq Mean Sq F value Pr(>F)
## Tax_group 2 0.0011 0.00055 0.233 0.793
## Prediction_tool 4 0.3712 0.09279 39.048 <2e-16 ***
## Tax_group:Prediction_tool 8 0.0076 0.00095 0.398 0.922
## Residuals 785 1.8654 0.00238
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1Statistically significant difference was detected so follow up with a Tukey test to determine if there are differences between groups.
bin.tax.acc.tukey <- TukeyHSD(bin.tax.acc.2.aov, "Tax_group:Prediction_tool")
write.csv(
as.data.frame(bin.tax.acc.tukey$`Tax_group:Prediction_tool`),
"../report/cazyme_noncazyme_classification/tax_performance/binary.acc.classifiers.tukeyHSD.csv"
)
bin.tax.acc.tukey## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistic_value ~ Tax_group * Prediction_tool, data = binary_tax_df[binary_tax_df$Statistic_parameter == "Accuracy", ])
##
## $`Tax_group:Prediction_tool`
## diff lwr
## Bacteria:CUPP-All:CUPP 0.0074375 -0.024679074
## Eukaryote:CUPP-All:CUPP -0.0074375 -0.039554074
## All:dbCAN_4-All:CUPP 0.0553750 0.029151927
## Bacteria:dbCAN_4-All:CUPP 0.0565625 0.024445926
## Eukaryote:dbCAN_4-All:CUPP 0.0541875 0.022070926
## All:dbCAN_4:dbCAN-sub-All:CUPP 0.0458125 0.019589427
## Bacteria:dbCAN_4:dbCAN-sub-All:CUPP 0.0515625 0.019445926
## Eukaryote:dbCAN_4:dbCAN-sub-All:CUPP 0.0400625 0.007945926
## All:dbCAN_4:DIAMOND-All:CUPP 0.0502500 0.024026927
## Bacteria:dbCAN_4:DIAMOND-All:CUPP 0.0469375 0.014820926
## Eukaryote:dbCAN_4:DIAMOND-All:CUPP 0.0535625 0.021445926
## All:dbCAN_4:HMMER-All:CUPP 0.0165625 -0.009660573
## Bacteria:dbCAN_4:HMMER-All:CUPP 0.0138125 -0.018304074
## Eukaryote:dbCAN_4:HMMER-All:CUPP 0.0193125 -0.012804074
## Eukaryote:CUPP-Bacteria:CUPP -0.0148750 -0.051960026
## All:dbCAN_4-Bacteria:CUPP 0.0479375 0.015820926
## Bacteria:dbCAN_4-Bacteria:CUPP 0.0491250 0.012039974
## Eukaryote:dbCAN_4-Bacteria:CUPP 0.0467500 0.009664974
## All:dbCAN_4:dbCAN-sub-Bacteria:CUPP 0.0383750 0.006258426
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:CUPP 0.0441250 0.007039974
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:CUPP 0.0326250 -0.004460026
## All:dbCAN_4:DIAMOND-Bacteria:CUPP 0.0428125 0.010695926
## Bacteria:dbCAN_4:DIAMOND-Bacteria:CUPP 0.0395000 0.002414974
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:CUPP 0.0461250 0.009039974
## All:dbCAN_4:HMMER-Bacteria:CUPP 0.0091250 -0.022991574
## Bacteria:dbCAN_4:HMMER-Bacteria:CUPP 0.0063750 -0.030710026
## Eukaryote:dbCAN_4:HMMER-Bacteria:CUPP 0.0118750 -0.025210026
## All:dbCAN_4-Eukaryote:CUPP 0.0628125 0.030695926
## Bacteria:dbCAN_4-Eukaryote:CUPP 0.0640000 0.026914974
## Eukaryote:dbCAN_4-Eukaryote:CUPP 0.0616250 0.024539974
## All:dbCAN_4:dbCAN-sub-Eukaryote:CUPP 0.0532500 0.021133426
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:CUPP 0.0590000 0.021914974
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:CUPP 0.0475000 0.010414974
## All:dbCAN_4:DIAMOND-Eukaryote:CUPP 0.0576875 0.025570926
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:CUPP 0.0543750 0.017289974
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:CUPP 0.0610000 0.023914974
## All:dbCAN_4:HMMER-Eukaryote:CUPP 0.0240000 -0.008116574
## Bacteria:dbCAN_4:HMMER-Eukaryote:CUPP 0.0212500 -0.015835026
## Eukaryote:dbCAN_4:HMMER-Eukaryote:CUPP 0.0267500 -0.010335026
## Bacteria:dbCAN_4-All:dbCAN_4 0.0011875 -0.030929074
## Eukaryote:dbCAN_4-All:dbCAN_4 -0.0011875 -0.033304074
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4 -0.0095625 -0.035785573
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4 -0.0038125 -0.035929074
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4 -0.0153125 -0.047429074
## All:dbCAN_4:DIAMOND-All:dbCAN_4 -0.0051250 -0.031348073
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4 -0.0084375 -0.040554074
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4 -0.0018125 -0.033929074
## All:dbCAN_4:HMMER-All:dbCAN_4 -0.0388125 -0.065035573
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4 -0.0415625 -0.073679074
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4 -0.0360625 -0.068179074
## Eukaryote:dbCAN_4-Bacteria:dbCAN_4 -0.0023750 -0.039460026
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 -0.0107500 -0.042866574
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 -0.0050000 -0.042085026
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 -0.0165000 -0.053585026
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 -0.0063125 -0.038429074
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 -0.0096250 -0.046710026
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 -0.0030000 -0.040085026
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4 -0.0400000 -0.072116574
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4 -0.0427500 -0.079835026
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4 -0.0372500 -0.074335026
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 -0.0083750 -0.040491574
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 -0.0026250 -0.039710026
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 -0.0141250 -0.051210026
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 -0.0039375 -0.036054074
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 -0.0072500 -0.044335026
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 -0.0006250 -0.037710026
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -0.0376250 -0.069741574
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -0.0403750 -0.077460026
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -0.0348750 -0.071960026
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub 0.0057500 -0.026366574
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub -0.0057500 -0.037866574
## All:dbCAN_4:DIAMOND-All:dbCAN_4:dbCAN-sub 0.0044375 -0.021785573
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:dbCAN-sub 0.0011250 -0.030991574
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:dbCAN-sub 0.0077500 -0.024366574
## All:dbCAN_4:HMMER-All:dbCAN_4:dbCAN-sub -0.0292500 -0.055473073
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:dbCAN-sub -0.0320000 -0.064116574
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:dbCAN-sub -0.0265000 -0.058616574
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:dbCAN-sub -0.0115000 -0.048585026
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:dbCAN-sub -0.0013125 -0.033429074
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:dbCAN-sub -0.0046250 -0.041710026
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:dbCAN-sub 0.0020000 -0.035085026
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4:dbCAN-sub -0.0350000 -0.067116574
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4:dbCAN-sub -0.0377500 -0.074835026
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:dbCAN-sub -0.0322500 -0.069335026
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:dbCAN-sub 0.0101875 -0.021929074
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:dbCAN-sub 0.0068750 -0.030210026
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:dbCAN-sub 0.0135000 -0.023585026
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4:dbCAN-sub -0.0235000 -0.055616574
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4:dbCAN-sub -0.0262500 -0.063335026
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4:dbCAN-sub -0.0207500 -0.057835026
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND -0.0033125 -0.035429074
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND 0.0033125 -0.028804074
## All:dbCAN_4:HMMER-All:dbCAN_4:DIAMOND -0.0336875 -0.059910573
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:DIAMOND -0.0364375 -0.068554074
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:DIAMOND -0.0309375 -0.063054074
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:DIAMOND 0.0066250 -0.030460026
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4:DIAMOND -0.0303750 -0.062491574
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4:DIAMOND -0.0331250 -0.070210026
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:DIAMOND -0.0276250 -0.064710026
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4:DIAMOND -0.0370000 -0.069116574
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4:DIAMOND -0.0397500 -0.076835026
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4:DIAMOND -0.0342500 -0.071335026
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:HMMER -0.0027500 -0.034866574
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:HMMER 0.0027500 -0.029366574
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:HMMER 0.0055000 -0.031585026
## upr p adj
## Bacteria:CUPP-All:CUPP 0.0395540744 0.9999788
## Eukaryote:CUPP-All:CUPP 0.0246790744 0.9999788
## All:dbCAN_4-All:CUPP 0.0815980732 0.0000000
## Bacteria:dbCAN_4-All:CUPP 0.0886790744 0.0000003
## Eukaryote:dbCAN_4-All:CUPP 0.0863040744 0.0000014
## All:dbCAN_4:dbCAN-sub-All:CUPP 0.0720355732 0.0000004
## Bacteria:dbCAN_4:dbCAN-sub-All:CUPP 0.0836790744 0.0000065
## Eukaryote:dbCAN_4:dbCAN-sub-All:CUPP 0.0721790744 0.0022755
## All:dbCAN_4:DIAMOND-All:CUPP 0.0764730732 0.0000000
## Bacteria:dbCAN_4:DIAMOND-All:CUPP 0.0790540744 0.0000819
## Eukaryote:dbCAN_4:DIAMOND-All:CUPP 0.0856790744 0.0000020
## All:dbCAN_4:HMMER-All:CUPP 0.0427855732 0.7013158
## Bacteria:dbCAN_4:HMMER-All:CUPP 0.0459290744 0.9808528
## Eukaryote:dbCAN_4:HMMER-All:CUPP 0.0514290744 0.7700538
## Eukaryote:CUPP-Bacteria:CUPP 0.0222100258 0.9900022
## All:dbCAN_4-Bacteria:CUPP 0.0800540744 0.0000483
## Bacteria:dbCAN_4-Bacteria:CUPP 0.0862100258 0.0007308
## Eukaryote:dbCAN_4-Bacteria:CUPP 0.0838350258 0.0018839
## All:dbCAN_4:dbCAN-sub-Bacteria:CUPP 0.0704915744 0.0047153
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:CUPP 0.0812100258 0.0050463
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:CUPP 0.0697100258 0.1584140
## All:dbCAN_4:DIAMOND-Bacteria:CUPP 0.0749290744 0.0006433
## Bacteria:dbCAN_4:DIAMOND-Bacteria:CUPP 0.0765850258 0.0241982
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:CUPP 0.0832100258 0.0023962
## All:dbCAN_4:HMMER-Bacteria:CUPP 0.0412415744 0.9997512
## Bacteria:dbCAN_4:HMMER-Bacteria:CUPP 0.0434600258 0.9999995
## Eukaryote:dbCAN_4:HMMER-Bacteria:CUPP 0.0489600258 0.9990324
## All:dbCAN_4-Eukaryote:CUPP 0.0949290744 0.0000000
## Bacteria:dbCAN_4-Eukaryote:CUPP 0.1010850258 0.0000007
## Eukaryote:dbCAN_4-Eukaryote:CUPP 0.0987100258 0.0000023
## All:dbCAN_4:dbCAN-sub-Eukaryote:CUPP 0.0853665744 0.0000024
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:CUPP 0.0960850258 0.0000085
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:CUPP 0.0845850258 0.0014048
## All:dbCAN_4:DIAMOND-Eukaryote:CUPP 0.0898040744 0.0000002
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:CUPP 0.0914600258 0.0000756
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:CUPP 0.0980850258 0.0000031
## All:dbCAN_4:HMMER-Eukaryote:CUPP 0.0561165744 0.4112308
## Bacteria:dbCAN_4:HMMER-Eukaryote:CUPP 0.0583350258 0.8269416
## Eukaryote:dbCAN_4:HMMER-Eukaryote:CUPP 0.0638350258 0.4752108
## Bacteria:dbCAN_4-All:dbCAN_4 0.0333040744 1.0000000
## Eukaryote:dbCAN_4-All:dbCAN_4 0.0309290744 1.0000000
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4 0.0166605732 0.9961224
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4 0.0283040744 1.0000000
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4 0.0168040744 0.9536334
## All:dbCAN_4:DIAMOND-All:dbCAN_4 0.0210980732 0.9999975
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4 0.0236790744 0.9999013
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4 0.0303040744 1.0000000
## All:dbCAN_4:HMMER-All:dbCAN_4 -0.0125894268 0.0000598
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4 -0.0094459256 0.0011554
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4 -0.0039459256 0.0120409
## Eukaryote:dbCAN_4-Bacteria:dbCAN_4 0.0347100258 1.0000000
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 0.0213665744 0.9984293
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 0.0320850258 1.0000000
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 0.0205850258 0.9741098
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 0.0258040744 0.9999973
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 0.0274600258 0.9999147
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 0.0340850258 1.0000000
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4 -0.0078834256 0.0023392
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4 -0.0056649742 0.0082308
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4 -0.0001649742 0.0476844
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 0.0237415744 0.9999097
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 0.0344600258 1.0000000
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 0.0229600258 0.9939745
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 0.0281790744 1.0000000
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 0.0298350258 0.9999975
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 0.0364600258 1.0000000
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -0.0055084256 0.0064415
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -0.0032899742 0.0183032
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4 0.0022100258 0.0913998
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub 0.0378665744 0.9999992
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub 0.0263665744 0.9999992
## All:dbCAN_4:DIAMOND-All:dbCAN_4:dbCAN-sub 0.0306605732 0.9999996
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:dbCAN-sub 0.0332415744 1.0000000
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:dbCAN-sub 0.0398665744 0.9999648
## All:dbCAN_4:HMMER-All:dbCAN_4:dbCAN-sub -0.0030269268 0.0132092
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:dbCAN-sub 0.0001165744 0.0519599
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:dbCAN-sub 0.0056165744 0.2449770
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:dbCAN-sub 0.0255850258 0.9993233
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:dbCAN-sub 0.0308040744 1.0000000
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:dbCAN-sub 0.0324600258 1.0000000
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:dbCAN-sub 0.0390850258 1.0000000
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4:dbCAN-sub -0.0028834256 0.0180702
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4:dbCAN-sub -0.0006649742 0.0412200
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:dbCAN-sub 0.0048350258 0.1724766
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:dbCAN-sub 0.0423040744 0.9991285
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:dbCAN-sub 0.0439600258 0.9999987
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:dbCAN-sub 0.0505850258 0.9961908
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4:dbCAN-sub 0.0086165744 0.4492530
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4:dbCAN-sub 0.0108350258 0.5093762
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4:dbCAN-sub 0.0163350258 0.8510599
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND 0.0288040744 1.0000000
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND 0.0354290744 1.0000000
## All:dbCAN_4:HMMER-All:dbCAN_4:DIAMOND -0.0074644268 0.0013284
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:DIAMOND -0.0043209256 0.0103940
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:DIAMOND 0.0011790744 0.0730239
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:DIAMOND 0.0437100258 0.9999992
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4:DIAMOND 0.0017415744 0.0867832
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4:DIAMOND 0.0039600258 0.1410087
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:DIAMOND 0.0094600258 0.4169373
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4:DIAMOND -0.0048834256 0.0083060
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4:DIAMOND -0.0026649742 0.0223621
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4:DIAMOND 0.0028350258 0.1072000
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:HMMER 0.0293665744 1.0000000
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:HMMER 0.0348665744 1.0000000
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:HMMER 0.0425850258 0.99999996 CAZy class classification
CAZy groups CAZymes into CAZy families by sequence similarity, and CAZy families are grouped into one of 6 functional classes. The CAZyme classifiers predict the CAZy family annotations of predicted CAZymes, but it is of interest to see what the level of performance of the classiferis is at the CAZy class level. Specifically, a classifier may struggle to predict the correct CAZy class for a CAZyme but consistently predict the correct CAZy class. Therefore, the aim of this part of the evaluation is to evaluate the performance of the classifiers to predict the correct CAZy class of predict CAZymes.
6.1 General trends in CAZy class classification performance
Below is a table summary all statistical parameters calculated in order to evaluate the performance of the CAZy class classification for each prediction tool across all CAZy classes.
| Classifier | Spec Mean | Spec Standard Deviation | Spec Lower CI | Spec Upper CI | Sens Mean | Sens Standard Deviation | Sens Lower CI | Sens Upper CI | Prec Mean | Prec Standard Deviation | Prec Lower CI | Prec Upper CI | F1-score Mean | F1-score Standard Deviation | F1-score Lower CI | F1-score Upper CI | Acc Mean | Acc Standard Deviation | Acc Lower CI | Acc Upper CI |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CUPP | 0.9953 | 0.0246 | 0.9929 | 0.9977 | 0.7144 | 0.3745 | 0.6781 | 0.7507 | 0.7785 | 0.3984 | 0.7399 | 0.8172 | 0.7389 | 0.3799 | 0.7021 | 0.7757 | 0.9538 | 0.0617 | 0.9479 | 0.9598 |
| dbCAN_4 | 0.9936 | 0.0267 | 0.9910 | 0.9962 | 0.9353 | 0.1289 | 0.9228 | 0.9478 | 0.9684 | 0.0939 | 0.9593 | 0.9775 | 0.9431 | 0.1040 | 0.9330 | 0.9532 | 0.9838 | 0.0328 | 0.9807 | 0.9870 |
| dbCAN_4:dbCAN-sub | 0.9931 | 0.0269 | 0.9905 | 0.9957 | 0.9369 | 0.1257 | 0.9247 | 0.9491 | 0.9643 | 0.1001 | 0.9546 | 0.9740 | 0.9424 | 0.1048 | 0.9322 | 0.9526 | 0.9833 | 0.0315 | 0.9802 | 0.9863 |
| dbCAN_4:DIAMOND | 0.9915 | 0.0285 | 0.9888 | 0.9943 | 0.9580 | 0.1108 | 0.9472 | 0.9687 | 0.9633 | 0.1152 | 0.9521 | 0.9745 | 0.9532 | 0.1047 | 0.9431 | 0.9634 | 0.9871 | 0.0324 | 0.9839 | 0.9902 |
| dbCAN_4:HMMER | 0.9941 | 0.0262 | 0.9915 | 0.9966 | 0.8428 | 0.2281 | 0.8207 | 0.8650 | 0.9616 | 0.1240 | 0.9495 | 0.9736 | 0.8766 | 0.1860 | 0.8586 | 0.8947 | 0.9689 | 0.0404 | 0.9650 | 0.9729 |
Here we plot the 95% confidence intervals for CAZy class classification, when pooling all CAZy classes and test sets.
Figure 6.1: Summary statistics of CAZyme classifiers performances of CAZy class classification, plotting the mean plus and minus the 95% confidence interval.
Figure 6.2: Summary statistics of CAZyme classifiers performances of CAZy class classification, plotting statistical patermate value per test set for binary CAZy class classification across all CAZy classes.
Below is a proportional area plot representing the F1-score for each CAZyme classifier for each test set. Each square is sized proportional to the relative sample size. Every class was not included in every sample, resulting in different sample sizes between CAZy classes.
Figure 6.3: Proportional area plot of CAZy class classification performance. Performance is represented by the F1-score. Plots are proptional to the number of test sets, after excluding true negative classifications.
A dataframe of the number of test sets containing each CAZy class is generated (table 6.2).
| Prediction_tool | GH | GT | PL | CE | AA | CBM |
|---|---|---|---|---|---|---|
| dbCAN_2 | 0 | 0 | 0 | 0 | 0 | 0 |
| dbCAN_2:HMMER | 0 | 0 | 0 | 0 | 0 | 0 |
| dbCAN_2:DIAMOND | 0 | 0 | 0 | 0 | 0 | 0 |
| dbCAN_2:Hotpep | 0 | 0 | 0 | 0 | 0 | 0 |
| dbCAN_3 | 0 | 0 | 0 | 0 | 0 | 0 |
| dbCAN_3:HMMER | 0 | 0 | 0 | 0 | 0 | 0 |
| dbCAN_3:DIAMOND | 0 | 0 | 0 | 0 | 0 | 0 |
| dbCAN_3:eCAMI | 0 | 0 | 0 | 0 | 0 | 0 |
| dbCAN_4 | 80 | 80 | 47 | 76 | 48 | 80 |
| dbCAN_4:HMMER | 80 | 80 | 47 | 76 | 48 | 80 |
| dbCAN_4:DIAMOND | 80 | 80 | 47 | 76 | 48 | 80 |
| dbCAN_4:dbCAN-sub | 80 | 80 | 47 | 76 | 48 | 80 |
| CUPP | 80 | 80 | 47 | 76 | 48 | 80 |
6.2 Statistically testing across all CAzy classes
Test for statistically significant differences between the means of the tools when pooling all CAZymes and CAZy classes and evaluating the overall performance of CAZy class classification.
Perform a one-way ANOVA to test for significant differences between the tools, and if found, using a post hoc Tukey HSD test to determine between which tools the means are significant different.
6.2.1 Specificity
## Df Sum Sq Mean Sq F value Pr(>F)
## Prediction_tool 4 0.0032 0.0007941 1.122 0.344
## Residuals 2050 1.4513 0.0007079## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistic_value ~ Prediction_tool, data = class_subset_spec.df)
##
## $Prediction_tool
## diff lwr upr
## dbCAN_4:HMMER-dbCAN_4 0.0004496256 -0.004617780 0.005517031
## dbCAN_4:DIAMOND-dbCAN_4 -0.0021005397 -0.007167945 0.002966866
## dbCAN_4:dbCAN-sub-dbCAN_4 -0.0005727506 -0.005640156 0.004494655
## CUPP-dbCAN_4 0.0016863933 -0.003381012 0.006753799
## dbCAN_4:DIAMOND-dbCAN_4:HMMER -0.0025501654 -0.007617571 0.002517240
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER -0.0010223762 -0.006089782 0.004045029
## CUPP-dbCAN_4:HMMER 0.0012367677 -0.003830638 0.006304173
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND 0.0015277891 -0.003539616 0.006595195
## CUPP-dbCAN_4:DIAMOND 0.0037869330 -0.001280472 0.008854338
## CUPP-dbCAN_4:dbCAN-sub 0.0022591439 -0.002808262 0.007326549
## p adj
## dbCAN_4:HMMER-dbCAN_4 0.9992401
## dbCAN_4:DIAMOND-dbCAN_4 0.7897247
## dbCAN_4:dbCAN-sub-dbCAN_4 0.9980328
## CUPP-dbCAN_4 0.8936933
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.6444930
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.9818545
## CUPP-dbCAN_4:HMMER 0.9635484
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND 0.9235532
## CUPP-dbCAN_4:DIAMOND 0.2470983
## CUPP-dbCAN_4:dbCAN-sub 0.74139916.2.2 Sensitivity
## Df Sum Sq Mean Sq F value Pr(>F)
## Prediction_tool 4 16.91 4.228 89.21 <2e-16 ***
## Residuals 2050 97.16 0.047
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistic_value ~ Prediction_tool, data = class_subset_sens.df)
##
## $Prediction_tool
## diff lwr upr
## dbCAN_4:HMMER-dbCAN_4 -0.092445854 -0.13390740 -0.05098431
## dbCAN_4:DIAMOND-dbCAN_4 0.022676068 -0.01878548 0.06413761
## dbCAN_4:dbCAN-sub-dbCAN_4 0.001642683 -0.03981886 0.04310423
## CUPP-dbCAN_4 -0.220885083 -0.26234663 -0.17942354
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.115121923 0.07366038 0.15658347
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.094088537 0.05262699 0.13555008
## CUPP-dbCAN_4:HMMER -0.128439229 -0.16990077 -0.08697768
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND -0.021033386 -0.06249493 0.02042816
## CUPP-dbCAN_4:DIAMOND -0.243561152 -0.28502270 -0.20209961
## CUPP-dbCAN_4:dbCAN-sub -0.222527766 -0.26398931 -0.18106622
## p adj
## dbCAN_4:HMMER-dbCAN_4 0.0000000
## dbCAN_4:DIAMOND-dbCAN_4 0.5670195
## dbCAN_4:dbCAN-sub-dbCAN_4 0.9999691
## CUPP-dbCAN_4 0.0000000
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.0000000
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.0000000
## CUPP-dbCAN_4:HMMER 0.0000000
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND 0.6373872
## CUPP-dbCAN_4:DIAMOND 0.0000000
## CUPP-dbCAN_4:dbCAN-sub 0.00000006.2.3 Precision
## Df Sum Sq Mean Sq F value Pr(>F)
## Prediction_tool 4 11.37 2.8428 68.93 <2e-16 ***
## Residuals 2050 84.54 0.0412
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistic_value ~ Prediction_tool, data = class_subset_prec.df)
##
## $Prediction_tool
## diff lwr upr
## dbCAN_4:HMMER-dbCAN_4 -0.006872007 -0.04554922 0.03180521
## dbCAN_4:DIAMOND-dbCAN_4 -0.005129266 -0.04380648 0.03354795
## dbCAN_4:dbCAN-sub-dbCAN_4 -0.004117221 -0.04279443 0.03455999
## CUPP-dbCAN_4 -0.189911432 -0.22858865 -0.15123422
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.001742741 -0.03693447 0.04041995
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.002754786 -0.03592243 0.04143200
## CUPP-dbCAN_4:HMMER -0.183039425 -0.22171664 -0.14436221
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND 0.001012045 -0.03766517 0.03968926
## CUPP-dbCAN_4:DIAMOND -0.184782166 -0.22345938 -0.14610495
## CUPP-dbCAN_4:dbCAN-sub -0.185794211 -0.22447142 -0.14711700
## p adj
## dbCAN_4:HMMER-dbCAN_4 0.9887401
## dbCAN_4:DIAMOND-dbCAN_4 0.9963331
## dbCAN_4:dbCAN-sub-dbCAN_4 0.9984444
## CUPP-dbCAN_4 0.0000000
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.9999484
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.9996814
## CUPP-dbCAN_4:HMMER 0.0000000
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND 0.9999941
## CUPP-dbCAN_4:DIAMOND 0.0000000
## CUPP-dbCAN_4:dbCAN-sub 0.00000006.2.4 F1-score
## Df Sum Sq Mean Sq F value Pr(>F)
## Prediction_tool 4 13.39 3.347 79.05 <2e-16 ***
## Residuals 2050 86.80 0.042
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistic_value ~ Prediction_tool, data = class_subset_f1.df)
##
## $Prediction_tool
## diff lwr upr
## dbCAN_4:HMMER-dbCAN_4 -0.0664890664 -0.10567785 -0.02730029
## dbCAN_4:DIAMOND-dbCAN_4 0.0101314621 -0.02905732 0.04932024
## dbCAN_4:dbCAN-sub-dbCAN_4 -0.0007078227 -0.03989660 0.03848096
## CUPP-dbCAN_4 -0.2042100746 -0.24339885 -0.16502130
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.0766205285 0.03743175 0.11580931
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.0657812437 0.02659246 0.10497002
## CUPP-dbCAN_4:HMMER -0.1377210081 -0.17690979 -0.09853223
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND -0.0108392848 -0.05002806 0.02834949
## CUPP-dbCAN_4:DIAMOND -0.2143415366 -0.25353032 -0.17515276
## CUPP-dbCAN_4:dbCAN-sub -0.2035022518 -0.24269103 -0.16431347
## p adj
## dbCAN_4:HMMER-dbCAN_4 0.0000378
## dbCAN_4:DIAMOND-dbCAN_4 0.9552156
## dbCAN_4:dbCAN-sub-dbCAN_4 0.9999987
## CUPP-dbCAN_4 0.0000000
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.0000010
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.0000477
## CUPP-dbCAN_4:HMMER 0.0000000
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND 0.9431947
## CUPP-dbCAN_4:DIAMOND 0.0000000
## CUPP-dbCAN_4:dbCAN-sub 0.00000006.2.5 Accuracy
## Df Sum Sq Mean Sq F value Pr(>F)
## Prediction_tool 4 0.319 0.07971 46.6 <2e-16 ***
## Residuals 2050 3.507 0.00171
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistic_value ~ Prediction_tool, data = class_subset_acc.df)
##
## $Prediction_tool
## diff lwr upr
## dbCAN_4:HMMER-dbCAN_4 -0.0148930422 -0.022770106 -0.007015978
## dbCAN_4:DIAMOND-dbCAN_4 0.0032107289 -0.004666335 0.011087793
## dbCAN_4:dbCAN-sub-dbCAN_4 -0.0005626154 -0.008439679 0.007314449
## CUPP-dbCAN_4 -0.0300054360 -0.037882500 -0.022128372
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.0181037711 0.010226707 0.025980835
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.0143304268 0.006453363 0.022207491
## CUPP-dbCAN_4:HMMER -0.0151123938 -0.022989458 -0.007235330
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND -0.0037733443 -0.011650408 0.004103720
## CUPP-dbCAN_4:DIAMOND -0.0332161649 -0.041093229 -0.025339101
## CUPP-dbCAN_4:dbCAN-sub -0.0294428206 -0.037319885 -0.021565757
## p adj
## dbCAN_4:HMMER-dbCAN_4 0.0000027
## dbCAN_4:DIAMOND-dbCAN_4 0.7998433
## dbCAN_4:dbCAN-sub-dbCAN_4 0.9996778
## CUPP-dbCAN_4 0.0000000
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.0000000
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.0000073
## CUPP-dbCAN_4:HMMER 0.0000018
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND 0.6863720
## CUPP-dbCAN_4:DIAMOND 0.0000000
## CUPP-dbCAN_4:dbCAN-sub 0.00000006.3 Sensitivity versus specificity
The sensitivity of each CAZyme classifier can be plotted against the specificity for each CAZy class, however plotting all CAZy classes in a single plot produces a cramped plot, unless very few test sets were used.
Figure 6.4: Scatter plot of sensitivity against specificity for predicting CAZy class members per CAZyme classier
6.4 Performance per CAZy class
Below the prediction sensitivity is plotted against the specificity for each classifier, and a separate plot is generated for each CAZy class.
The scatter plots of sensitivity against specificity overlay a coloured contour to highlight the distribution of the points. When too many points have the same value a contour cannot be generated. In order to plot a contour noise is added to the data. The original data is used to plot the scatter plot and the data with added noise is used to plot the contour.
The percentage of the data points which need noise to be added to them in order to generate a contour varies from data set to data set. To change the percentage of the data points with noise added to them, change the third value of call to the function plot.class.sens.vs.spec(), which is used to generate the plots. The third value is the percentage of data points to add noise to, written in decimal form.
6.4.1 GH class classification
| Prediction_tool | Spec Mean | Spec Standard Deviation | Spec CI Lower | Spec CI Upper | Sens Mean | Sens Standard Deviation | Sens CI Lower | Sens CI Upper | Prec Mean | Prec Standard Deviation | Prec CI Lower | Prec CI Upper | F1-score Mean | F1-score Standard Deviation | F1-score CI Lower | F1-score CI Upper | Acc Mean | Acc Standard Deviation | Acc CI Lower | Acc CI Upper |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CUPP | 0.9933 | 0.0212 | 0.9886 | 0.9980 | 0.9080 | 0.0675 | 0.8930 | 0.9230 | 0.9906 | 0.0338 | 0.9831 | 0.9981 | 0.9461 | 0.0454 | 0.9360 | 0.9562 | 0.9540 | 0.0293 | 0.9475 | 0.9605 |
| dbCAN_4 | 0.9927 | 0.0240 | 0.9873 | 0.9980 | 0.9500 | 0.0802 | 0.9322 | 0.9679 | 0.9898 | 0.0337 | 0.9823 | 0.9973 | 0.9671 | 0.0590 | 0.9539 | 0.9802 | 0.9743 | 0.0307 | 0.9675 | 0.9812 |
| dbCAN_4:dbCAN-sub | 0.9924 | 0.0238 | 0.9871 | 0.9977 | 0.9473 | 0.0789 | 0.9297 | 0.9648 | 0.9896 | 0.0337 | 0.9821 | 0.9971 | 0.9655 | 0.0581 | 0.9526 | 0.9785 | 0.9731 | 0.0297 | 0.9665 | 0.9797 |
| dbCAN_4:DIAMOND | 0.9864 | 0.0279 | 0.9802 | 0.9927 | 0.9737 | 0.0763 | 0.9567 | 0.9906 | 0.9842 | 0.0393 | 0.9754 | 0.9929 | 0.9764 | 0.0583 | 0.9634 | 0.9894 | 0.9812 | 0.0304 | 0.9745 | 0.9880 |
| dbCAN_4:HMMER | 0.9939 | 0.0224 | 0.9889 | 0.9988 | 0.9202 | 0.0828 | 0.9017 | 0.9386 | 0.9909 | 0.0330 | 0.9836 | 0.9983 | 0.9516 | 0.0596 | 0.9384 | 0.9649 | 0.9601 | 0.0328 | 0.9528 | 0.9674 |
Figure 6.5: Scatter plot of sensitivity against specificity for predicting GH CAZy class members per CAZyme classier, overlaying a density map.
Figure 6.6: Summary statistics of CAZyme classifiers performances of GH class classification, plotting the mean plus and minus the 95% confidence interval.
Figure 6.7: One dimensional scatter plot of the statistical parameters per test set for the classification of GH class members, overlaying a box plot
6.4.1.1 Specificity test
A one-way ANOVA was performed to determine if the mean specificity was statistically significantly different between the tools.
## Df Sum Sq Mean Sq F value Pr(>F)
## Prediction_tool 4 0.0029 0.0007249 1.259 0.285
## Residuals 395 0.2274 0.0005757The means are statistically significantly different, therefore, use a post hoc Turkey HSD test to determine between which tools the means are significantly difference.
## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistic_value ~ Prediction_tool, data = gh_subset_spec.df)
##
## $Prediction_tool
## diff lwr upr
## dbCAN_4:HMMER-dbCAN_4 0.0011981447 -0.009198283 0.011594572
## dbCAN_4:DIAMOND-dbCAN_4 -0.0062213497 -0.016617777 0.004175078
## dbCAN_4:dbCAN-sub-dbCAN_4 -0.0002586476 -0.010655075 0.010137780
## CUPP-dbCAN_4 0.0006204571 -0.009775971 0.011016885
## dbCAN_4:DIAMOND-dbCAN_4:HMMER -0.0074194944 -0.017815922 0.002976933
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER -0.0014567923 -0.011853220 0.008939635
## CUPP-dbCAN_4:HMMER -0.0005776876 -0.010974115 0.009818740
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND 0.0059627021 -0.004433726 0.016359130
## CUPP-dbCAN_4:DIAMOND 0.0068418068 -0.003554621 0.017238235
## CUPP-dbCAN_4:dbCAN-sub 0.0008791047 -0.009517323 0.011275532
## p adj
## dbCAN_4:HMMER-dbCAN_4 0.9978382
## dbCAN_4:DIAMOND-dbCAN_4 0.4727694
## dbCAN_4:dbCAN-sub-dbCAN_4 0.9999951
## CUPP-dbCAN_4 0.9998391
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.2898661
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.9953795
## CUPP-dbCAN_4:HMMER 0.9998789
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND 0.5164752
## CUPP-dbCAN_4:DIAMOND 0.3729882
## CUPP-dbCAN_4:dbCAN-sub 0.99935986.4.1.2 Sensitivity test
A one-way ANOVA was performed to determine if the mean sensitivity was statistically significantly different between the tools.
## Df Sum Sq Mean Sq F value Pr(>F)
## Prediction_tool 4 0.2163 0.05407 9.048 5.32e-07 ***
## Residuals 395 2.3607 0.00598
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1The means are statistically significantly different, therefore, use a post hoc Turkey HSD test to determine between which tools the means are significantly difference.
## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistic_value ~ Prediction_tool, data = gh_subset_sens.df)
##
## $Prediction_tool
## diff lwr upr
## dbCAN_4:HMMER-dbCAN_4 -0.029857290 -0.063354446 0.003639867
## dbCAN_4:DIAMOND-dbCAN_4 0.023636992 -0.009860165 0.057134148
## dbCAN_4:dbCAN-sub-dbCAN_4 -0.002772773 -0.036269929 0.030724383
## CUPP-dbCAN_4 -0.042029464 -0.075526620 -0.008532307
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.053494281 0.019997125 0.086991438
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.027084517 -0.006412640 0.060581673
## CUPP-dbCAN_4:HMMER -0.012172174 -0.045669331 0.021324982
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND -0.026409765 -0.059906921 0.007087392
## CUPP-dbCAN_4:DIAMOND -0.065666456 -0.099163612 -0.032169299
## CUPP-dbCAN_4:dbCAN-sub -0.039256691 -0.072753847 -0.005759535
## p adj
## dbCAN_4:HMMER-dbCAN_4 0.1063026
## dbCAN_4:DIAMOND-dbCAN_4 0.3011611
## dbCAN_4:dbCAN-sub-dbCAN_4 0.9994115
## CUPP-dbCAN_4 0.0058093
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.0001500
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.1759517
## CUPP-dbCAN_4:HMMER 0.8571855
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND 0.1970161
## CUPP-dbCAN_4:DIAMOND 0.0000013
## CUPP-dbCAN_4:dbCAN-sub 0.01237296.4.1.3 Precision test
A one-way ANOVA was performed to determine if the mean precision was statistically significantly different between the tools.
## Df Sum Sq Mean Sq F value Pr(>F)
## Prediction_tool 4 0.0025 0.0006135 0.508 0.73
## Residuals 395 0.4774 0.0012086The means are not statistically significantly different.
6.4.1.4 F1 test
A one-way ANOVA was performed to determine if the mean F1-scores was statistically significantly different between the tools.
## Df Sum Sq Mean Sq F value Pr(>F)
## Prediction_tool 4 0.0484 0.012088 3.811 0.00471 **
## Residuals 395 1.2528 0.003172
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1The means are statistically significantly different, therefore, use a post hoc Turkey HSD test to determine between which tools the means are significantly difference.
## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistic_value ~ Prediction_tool, data = gh_subset_f1.df)
##
## $Prediction_tool
## diff lwr upr
## dbCAN_4:HMMER-dbCAN_4 -0.015420178 -0.0398224204 0.008982064
## dbCAN_4:DIAMOND-dbCAN_4 0.009334620 -0.0150676220 0.033736862
## dbCAN_4:dbCAN-sub-dbCAN_4 -0.001501562 -0.0259038042 0.022900680
## CUPP-dbCAN_4 -0.020988869 -0.0453911111 0.003413373
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.024754798 0.0003525563 0.049157041
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.013918616 -0.0104836259 0.038320858
## CUPP-dbCAN_4:HMMER -0.005568691 -0.0299709329 0.018833551
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND -0.010836182 -0.0352384244 0.013566060
## CUPP-dbCAN_4:DIAMOND -0.030323489 -0.0547257313 -0.005921247
## CUPP-dbCAN_4:dbCAN-sub -0.019487307 -0.0438895491 0.004914935
## p adj
## dbCAN_4:HMMER-dbCAN_4 0.4156521
## dbCAN_4:DIAMOND-dbCAN_4 0.8325885
## dbCAN_4:dbCAN-sub-dbCAN_4 0.9998183
## CUPP-dbCAN_4 0.1294986
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.0448831
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.5220632
## CUPP-dbCAN_4:HMMER 0.9709547
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND 0.7415532
## CUPP-dbCAN_4:DIAMOND 0.0065073
## CUPP-dbCAN_4:dbCAN-sub 0.18617336.4.1.5 Accuracy test
A one-way ANOVA was performed to determine if the mean accuracy was statistically significantly different between the tools.
## Df Sum Sq Mean Sq F value Pr(>F)
## Prediction_tool 4 0.0399 0.009970 10.64 3.36e-08 ***
## Residuals 395 0.3700 0.000937
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1The means are statistically significantly different, therefore, use a post hoc Turkey HSD test to determine between which tools the means are significantly difference.
## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistic_value ~ Prediction_tool, data = gh_subset_acc.df)
##
## $Prediction_tool
## diff lwr upr
## dbCAN_4:HMMER-dbCAN_4 -0.014219593 -0.0274814184 -0.0009577668
## dbCAN_4:DIAMOND-dbCAN_4 0.006895056 -0.0063667695 0.0201568820
## dbCAN_4:dbCAN-sub-dbCAN_4 -0.001209470 -0.0144712953 0.0120523563
## CUPP-dbCAN_4 -0.020351666 -0.0336134920 -0.0070898405
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.021114649 0.0078528230 0.0343764746
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.013010123 -0.0002517027 0.0262719488
## CUPP-dbCAN_4:HMMER -0.006132074 -0.0193938994 0.0071297521
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND -0.008104526 -0.0213663515 0.0051573000
## CUPP-dbCAN_4:DIAMOND -0.027246722 -0.0405085482 -0.0139848967
## CUPP-dbCAN_4:dbCAN-sub -0.019142197 -0.0324040225 -0.0058803710
## p adj
## dbCAN_4:HMMER-dbCAN_4 0.0286421
## dbCAN_4:DIAMOND-dbCAN_4 0.6120073
## dbCAN_4:dbCAN-sub-dbCAN_4 0.9991373
## CUPP-dbCAN_4 0.0003104
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.0001589
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.0574635
## CUPP-dbCAN_4:HMMER 0.7115593
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND 0.4508297
## CUPP-dbCAN_4:DIAMOND 0.0000003
## CUPP-dbCAN_4:dbCAN-sub 0.00085696.4.2 GT class classification
| Prediction_tool | Spec Mean | Spec Standard Deviation | Spec CI Lower | Spec CI Upper | Sens Mean | Sens Standard Deviation | Sens CI Lower | Sens CI Upper | Prec Mean | Prec Standard Deviation | Prec CI Lower | Prec CI Upper | F1-score Mean | F1-score Standard Deviation | F1-score CI Lower | F1-score CI Upper | Acc Mean | Acc Standard Deviation | Acc CI Lower | Acc CI Upper |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CUPP | 0.9921 | 0.0463 | 0.9818 | 1.0024 | 0.8536 | 0.1107 | 0.8289 | 0.8782 | 0.9883 | 0.0625 | 0.9744 | 1.0022 | 0.9107 | 0.0758 | 0.8938 | 0.9276 | 0.9462 | 0.0579 | 0.9333 | 0.9591 |
| dbCAN_4 | 0.9900 | 0.0492 | 0.9790 | 1.0009 | 0.9578 | 0.0921 | 0.9373 | 0.9783 | 0.9866 | 0.0566 | 0.9740 | 0.9992 | 0.9677 | 0.0753 | 0.9510 | 0.9845 | 0.9781 | 0.0572 | 0.9654 | 0.9909 |
| dbCAN_4:dbCAN-sub | 0.9900 | 0.0492 | 0.9790 | 1.0009 | 0.9538 | 0.0835 | 0.9352 | 0.9724 | 0.9866 | 0.0566 | 0.9740 | 0.9992 | 0.9664 | 0.0656 | 0.9518 | 0.9810 | 0.9773 | 0.0519 | 0.9657 | 0.9889 |
| dbCAN_4:DIAMOND | 0.9893 | 0.0488 | 0.9785 | 1.0002 | 0.9751 | 0.0914 | 0.9548 | 0.9954 | 0.9841 | 0.0638 | 0.9699 | 0.9983 | 0.9750 | 0.0781 | 0.9577 | 0.9924 | 0.9838 | 0.0577 | 0.9710 | 0.9966 |
| dbCAN_4:HMMER | 0.9904 | 0.0487 | 0.9796 | 1.0012 | 0.8657 | 0.1110 | 0.8410 | 0.8904 | 0.9884 | 0.0566 | 0.9758 | 1.0010 | 0.9170 | 0.0838 | 0.8984 | 0.9357 | 0.9503 | 0.0597 | 0.9370 | 0.9635 |
Figure 6.8: Scatter plot of sensitivity against specificity for predicting GT CAZy class members per CAZyme classier, overlaying a density map.
Figure 6.9: Summary statistics of CAZyme classifiers performances of GT class classification, plotting the mean plus and minus the 95% confidence interval.
Figure 6.10: One dimensional scatter plot of the statistical parameters per test set for the classification of GT class members, overlaying a box plot
6.4.2.1 Specificity test
A one-way ANOVA was performed to determine if the mean specificity was statistically significantly different between the tools.
## Df Sum Sq Mean Sq F value Pr(>F)
## Prediction_tool 4 0.0003 0.0000873 0.037 0.997
## Residuals 395 0.9267 0.0023461The means are not statistically significantly different.
6.4.2.2 Sensitivity test
A one-way ANOVA was performed to determine if the mean sensitivity was statistically significantly different between the tools.
## Df Sum Sq Mean Sq F value Pr(>F)
## Prediction_tool 4 1.037 0.25929 26.79 <2e-16 ***
## Residuals 395 3.823 0.00968
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1The means are statistically significantly different, therefore, use a post hoc Turkey HSD test to determine between which tools the means are significantly difference.
## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistic_value ~ Prediction_tool, data = gt_subset_sens.df)
##
## $Prediction_tool
## diff lwr upr
## dbCAN_4:HMMER-dbCAN_4 -0.092128609 -0.13475577 -0.04950144
## dbCAN_4:DIAMOND-dbCAN_4 0.017274546 -0.02535262 0.05990171
## dbCAN_4:dbCAN-sub-dbCAN_4 -0.004008896 -0.04663606 0.03861827
## CUPP-dbCAN_4 -0.104252866 -0.14688003 -0.06162570
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.109403155 0.06677599 0.15203032
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.088119713 0.04549255 0.13074688
## CUPP-dbCAN_4:HMMER -0.012124257 -0.05475142 0.03050291
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND -0.021283442 -0.06391061 0.02134372
## CUPP-dbCAN_4:DIAMOND -0.121527412 -0.16415458 -0.07890025
## CUPP-dbCAN_4:dbCAN-sub -0.100243970 -0.14287114 -0.05761680
## p adj
## dbCAN_4:HMMER-dbCAN_4 0.0000001
## dbCAN_4:DIAMOND-dbCAN_4 0.8009660
## dbCAN_4:dbCAN-sub-dbCAN_4 0.9990263
## CUPP-dbCAN_4 0.0000000
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.0000000
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.0000003
## CUPP-dbCAN_4:HMMER 0.9364610
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND 0.6483833
## CUPP-dbCAN_4:DIAMOND 0.0000000
## CUPP-dbCAN_4:dbCAN-sub 0.00000006.4.2.3 Precision test
A one-way ANOVA was performed to determine if the mean precision was statistically significantly different between the tools.
## Df Sum Sq Mean Sq F value Pr(>F)
## Prediction_tool 4 0.001 0.000247 0.07 0.991
## Residuals 395 1.389 0.003517The means are not statistically significantly different.
6.4.2.4 F1 test
A one-way ANOVA was performed to determine if the mean F1-scores was statistically significantly different between the tools.
## Df Sum Sq Mean Sq F value Pr(>F)
## Prediction_tool 4 0.3044 0.07611 13.19 4.27e-10 ***
## Residuals 395 2.2788 0.00577
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1The means are statistically significantly different, therefore, use a post hoc Turkey HSD test to determine between which tools the means are significantly difference.
## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistic_value ~ Prediction_tool, data = gt_subset_f1.df)
##
## $Prediction_tool
## diff lwr upr
## dbCAN_4:HMMER-dbCAN_4 -0.050699725 -0.08361113 -0.01778832
## dbCAN_4:DIAMOND-dbCAN_4 0.007295471 -0.02561594 0.04020688
## dbCAN_4:dbCAN-sub-dbCAN_4 -0.001369053 -0.03428046 0.03154236
## CUPP-dbCAN_4 -0.057031131 -0.08994254 -0.02411972
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.057995196 0.02508379 0.09090661
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.049330672 0.01641926 0.08224208
## CUPP-dbCAN_4:HMMER -0.006331406 -0.03924282 0.02658000
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND -0.008664523 -0.04157593 0.02424689
## CUPP-dbCAN_4:DIAMOND -0.064326602 -0.09723801 -0.03141519
## CUPP-dbCAN_4:dbCAN-sub -0.055662078 -0.08857349 -0.02275067
## p adj
## dbCAN_4:HMMER-dbCAN_4 0.0002901
## dbCAN_4:DIAMOND-dbCAN_4 0.9738785
## dbCAN_4:dbCAN-sub-dbCAN_4 0.9999618
## CUPP-dbCAN_4 0.0000282
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.0000194
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.0004651
## CUPP-dbCAN_4:HMMER 0.9845485
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND 0.9514929
## CUPP-dbCAN_4:DIAMOND 0.0000014
## CUPP-dbCAN_4:dbCAN-sub 0.00004766.4.2.5 Accuracy test
A one-way ANOVA was performed to determine if the mean accuracy was statistically significantly different between the tools.
## Df Sum Sq Mean Sq F value Pr(>F)
## Prediction_tool 4 0.098 0.024494 7.558 7.11e-06 ***
## Residuals 395 1.280 0.003241
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1The means are statistically significantly different, therefore, use a post hoc Turkey HSD test to determine between which tools the means are significantly difference.
## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistic_value ~ Prediction_tool, data = gt_subset_acc.df)
##
## $Prediction_tool
## diff lwr upr
## dbCAN_4:HMMER-dbCAN_4 -0.0278694046 -0.052536578 -0.003202231
## dbCAN_4:DIAMOND-dbCAN_4 0.0056632974 -0.019003876 0.030330471
## dbCAN_4:dbCAN-sub-dbCAN_4 -0.0008336128 -0.025500786 0.023833560
## CUPP-dbCAN_4 -0.0319307447 -0.056597918 -0.007263572
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.0335327019 0.008865529 0.058199875
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.0270357918 0.002368619 0.051702965
## CUPP-dbCAN_4:HMMER -0.0040613402 -0.028728513 0.020605833
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND -0.0064969102 -0.031164083 0.018170263
## CUPP-dbCAN_4:DIAMOND -0.0375940421 -0.062261215 -0.012926869
## CUPP-dbCAN_4:dbCAN-sub -0.0310971319 -0.055764305 -0.006429959
## p adj
## dbCAN_4:HMMER-dbCAN_4 0.0178104
## dbCAN_4:DIAMOND-dbCAN_4 0.9703082
## dbCAN_4:dbCAN-sub-dbCAN_4 0.9999833
## CUPP-dbCAN_4 0.0039667
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.0020739
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.0236129
## CUPP-dbCAN_4:HMMER 0.9914198
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND 0.9514183
## CUPP-dbCAN_4:DIAMOND 0.0003501
## CUPP-dbCAN_4:dbCAN-sub 0.00549086.4.3 PL class classification
| Prediction_tool | Spec Mean | Spec Standard Deviation | Spec CI Lower | Spec CI Upper | Sens Mean | Sens Standard Deviation | Sens CI Lower | Sens CI Upper | Prec Mean | Prec Standard Deviation | Prec CI Lower | Prec CI Upper | F1-score Mean | F1-score Standard Deviation | F1-score CI Lower | F1-score CI Upper | Acc Mean | Acc Standard Deviation | Acc CI Lower | Acc CI Upper |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CUPP | 0.9996 | 0.0019 | 0.9990 | 1.0002 | 0.8511 | 0.2593 | 0.7749 | 0.9272 | 0.9496 | 0.2058 | 0.8892 | 1.0101 | 0.8850 | 0.2288 | 0.8178 | 0.9522 | 0.9941 | 0.0096 | 0.9913 | 0.9970 |
| dbCAN_4 | 0.9994 | 0.0025 | 0.9986 | 1.0001 | 0.9739 | 0.0982 | 0.9451 | 1.0028 | 0.9846 | 0.0766 | 0.9621 | 1.0071 | 0.9741 | 0.0781 | 0.9511 | 0.9970 | 0.9986 | 0.0035 | 0.9975 | 0.9996 |
| dbCAN_4:dbCAN-sub | 0.9994 | 0.0025 | 0.9986 | 1.0001 | 0.9752 | 0.0982 | 0.9464 | 1.0040 | 0.9846 | 0.0766 | 0.9621 | 1.0071 | 0.9747 | 0.0782 | 0.9518 | 0.9977 | 0.9988 | 0.0032 | 0.9978 | 0.9997 |
| dbCAN_4:DIAMOND | 0.9989 | 0.0039 | 0.9978 | 1.0000 | 0.9987 | 0.0086 | 0.9962 | 1.0013 | 0.9730 | 0.1012 | 0.9433 | 1.0028 | 0.9825 | 0.0646 | 0.9635 | 1.0014 | 0.9988 | 0.0039 | 0.9976 | 0.9999 |
| dbCAN_4:HMMER | 0.9994 | 0.0025 | 0.9986 | 1.0001 | 0.9739 | 0.0982 | 0.9451 | 1.0028 | 0.9846 | 0.0766 | 0.9621 | 1.0071 | 0.9741 | 0.0781 | 0.9511 | 0.9970 | 0.9986 | 0.0035 | 0.9975 | 0.9996 |
Figure 6.11: Scatter plot of sensitivity against specificity for predicting PL CAZy class members per CAZyme classier, overlaying a density map.
Figure 6.12: Summary statistics of CAZyme classifiers performances of PL class classification, plotting the mean plus and minus the 95% confidence interval.
Figure 6.13: One dimensional scatter plot of the statistical parameters per test set for the classification of PL class members, overlaying a box plot
6.4.3.1 Specificity test
A one-way ANOVA was performed to determine if the mean specificity was statistically significantly different between the tools.
## Df Sum Sq Mean Sq F value Pr(>F)
## Prediction_tool 4 1.21e-05 3.033e-06 0.408 0.803
## Residuals 230 1.71e-03 7.433e-06The means are not statistically significantly different.
6.4.3.2 Sensitivity test
A one-way ANOVA was performed to determine if the mean sensitivity was statistically significantly different between the tools.
## Df Sum Sq Mean Sq F value Pr(>F)
## Prediction_tool 4 0.650 0.16258 8.448 2.24e-06 ***
## Residuals 230 4.426 0.01924
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1The means are statistically significantly different, therefore, use a post hoc Turkey HSD test to determine between which tools the means are significantly difference.
## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistic_value ~ Prediction_tool, data = pl_subset_sens.df)
##
## $Prediction_tool
## diff lwr upr
## dbCAN_4:HMMER-dbCAN_4 2.220446e-16 -0.07868366 0.07868366
## dbCAN_4:DIAMOND-dbCAN_4 2.482270e-02 -0.05386096 0.10350635
## dbCAN_4:dbCAN-sub-dbCAN_4 1.251564e-03 -0.07743209 0.07993522
## CUPP-dbCAN_4 -1.228512e-01 -0.20153489 -0.04416757
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 2.482270e-02 -0.05386096 0.10350635
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 1.251564e-03 -0.07743209 0.07993522
## CUPP-dbCAN_4:HMMER -1.228512e-01 -0.20153489 -0.04416757
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND -2.357113e-02 -0.10225479 0.05511253
## CUPP-dbCAN_4:DIAMOND -1.476739e-01 -0.22635759 -0.06899027
## CUPP-dbCAN_4:dbCAN-sub -1.241028e-01 -0.20278645 -0.04541914
## p adj
## dbCAN_4:HMMER-dbCAN_4 1.0000000
## dbCAN_4:DIAMOND-dbCAN_4 0.9085247
## dbCAN_4:dbCAN-sub-dbCAN_4 0.9999992
## CUPP-dbCAN_4 0.0002502
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.9085247
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.9999992
## CUPP-dbCAN_4:HMMER 0.0002502
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND 0.9231185
## CUPP-dbCAN_4:DIAMOND 0.0000053
## CUPP-dbCAN_4:dbCAN-sub 0.00020886.4.3.3 Precision test
A one-way ANOVA was performed to determine if the mean precision was statistically significantly different between the tools.
## Df Sum Sq Mean Sq F value Pr(>F)
## Prediction_tool 4 0.043 0.01082 0.77 0.545
## Residuals 230 3.230 0.01404The means are not statistically significantly different.
6.4.3.4 F1 test
A one-way ANOVA was performed to determine if the mean F1-scores was statistically significantly different between the tools.
## Df Sum Sq Mean Sq F value Pr(>F)
## Prediction_tool 4 0.316 0.07898 5.275 0.000441 ***
## Residuals 230 3.444 0.01497
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1The means are statistically significantly different, therefore, use a post hoc Turkey HSD test to determine between which tools the means are significantly difference.
## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistic_value ~ Prediction_tool, data = pl_subset_f1.df)
##
## $Prediction_tool
## diff lwr upr
## dbCAN_4:HMMER-dbCAN_4 2.220446e-16 -0.06940222 0.06940222
## dbCAN_4:DIAMOND-dbCAN_4 8.371770e-03 -0.06103045 0.07777400
## dbCAN_4:dbCAN-sub-dbCAN_4 6.447453e-04 -0.06875748 0.07004697
## CUPP-dbCAN_4 -8.906369e-02 -0.15846591 -0.01966146
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 8.371770e-03 -0.06103045 0.07777400
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 6.447453e-04 -0.06875748 0.07004697
## CUPP-dbCAN_4:HMMER -8.906369e-02 -0.15846591 -0.01966146
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND -7.727025e-03 -0.07712925 0.06167520
## CUPP-dbCAN_4:DIAMOND -9.743546e-02 -0.16683768 -0.02803323
## CUPP-dbCAN_4:dbCAN-sub -8.970843e-02 -0.15911066 -0.02030621
## p adj
## dbCAN_4:HMMER-dbCAN_4 1.0000000
## dbCAN_4:DIAMOND-dbCAN_4 0.9973747
## dbCAN_4:dbCAN-sub-dbCAN_4 0.9999999
## CUPP-dbCAN_4 0.0045531
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.9973747
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.9999999
## CUPP-dbCAN_4:HMMER 0.0045531
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND 0.9980800
## CUPP-dbCAN_4:DIAMOND 0.0013760
## CUPP-dbCAN_4:dbCAN-sub 0.00416706.4.3.5 Accuracy test
A one-way ANOVA was performed to determine if the mean accuracy was statistically significantly different between the tools.
## Df Sum Sq Mean Sq F value Pr(>F)
## Prediction_tool 4 0.000768 1.921e-04 6.777 3.58e-05 ***
## Residuals 230 0.006521 2.835e-05
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1The means are statistically significantly different, therefore, use a post hoc Turkey HSD test to determine between which tools the means are significantly difference.
## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistic_value ~ Prediction_tool, data = pl_subset_acc.df)
##
## $Prediction_tool
## diff lwr upr
## dbCAN_4:HMMER-dbCAN_4 -5.352518e-06 -0.003025327 0.003014622
## dbCAN_4:DIAMOND-dbCAN_4 1.873251e-04 -0.002832650 0.003207300
## dbCAN_4:dbCAN-sub-dbCAN_4 2.160726e-04 -0.002803902 0.003236047
## CUPP-dbCAN_4 -4.415464e-03 -0.007435439 -0.001395489
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 1.926777e-04 -0.002827297 0.003212652
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 2.214251e-04 -0.002798550 0.003241400
## CUPP-dbCAN_4:HMMER -4.410112e-03 -0.007430086 -0.001390137
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND 2.874747e-05 -0.002991227 0.003048722
## CUPP-dbCAN_4:DIAMOND -4.602789e-03 -0.007622764 -0.001582815
## CUPP-dbCAN_4:dbCAN-sub -4.631537e-03 -0.007651511 -0.001611562
## p adj
## dbCAN_4:HMMER-dbCAN_4 1.0000000
## dbCAN_4:DIAMOND-dbCAN_4 0.9998093
## dbCAN_4:dbCAN-sub-dbCAN_4 0.9996639
## CUPP-dbCAN_4 0.0007465
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.9997867
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.9996297
## CUPP-dbCAN_4:HMMER 0.0007607
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND 0.9999999
## CUPP-dbCAN_4:DIAMOND 0.0003796
## CUPP-dbCAN_4:dbCAN-sub 0.00034156.4.4 CE class classification
| Prediction_tool | Spec Mean | Spec Standard Deviation | Spec CI Lower | Spec CI Upper | Sens Mean | Sens Standard Deviation | Sens CI Lower | Sens CI Upper | Prec Mean | Prec Standard Deviation | Prec CI Lower | Prec CI Upper | F1-score Mean | F1-score Standard Deviation | F1-score CI Lower | F1-score CI Upper | Acc Mean | Acc Standard Deviation | Acc CI Lower | Acc CI Upper |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CUPP | 0.9955 | 0.0178 | 0.9914 | 0.9995 | 0.9114 | 0.1332 | 0.8810 | 0.9419 | 0.9598 | 0.1130 | 0.9339 | 0.9856 | 0.9250 | 0.1095 | 0.9000 | 0.9500 | 0.9900 | 0.0187 | 0.9857 | 0.9943 |
| dbCAN_4 | 0.9953 | 0.0179 | 0.9912 | 0.9994 | 0.9783 | 0.0669 | 0.9630 | 0.9935 | 0.9603 | 0.1103 | 0.9351 | 0.9855 | 0.9638 | 0.0854 | 0.9443 | 0.9833 | 0.9943 | 0.0172 | 0.9904 | 0.9982 |
| dbCAN_4:dbCAN-sub | 0.9952 | 0.0181 | 0.9911 | 0.9993 | 0.9755 | 0.0680 | 0.9599 | 0.9910 | 0.9592 | 0.1120 | 0.9336 | 0.9848 | 0.9617 | 0.0863 | 0.9420 | 0.9814 | 0.9938 | 0.0175 | 0.9898 | 0.9978 |
| dbCAN_4:DIAMOND | 0.9931 | 0.0227 | 0.9879 | 0.9983 | 0.9755 | 0.0851 | 0.9560 | 0.9949 | 0.9476 | 0.1506 | 0.9132 | 0.9820 | 0.9507 | 0.1192 | 0.9234 | 0.9779 | 0.9919 | 0.0218 | 0.9870 | 0.9969 |
| dbCAN_4:HMMER | 0.9953 | 0.0179 | 0.9912 | 0.9994 | 0.9529 | 0.1012 | 0.9298 | 0.9760 | 0.9603 | 0.1103 | 0.9351 | 0.9855 | 0.9487 | 0.0957 | 0.9268 | 0.9706 | 0.9929 | 0.0173 | 0.9889 | 0.9968 |
Figure 6.14: Scatter plot of sensitivity against specificity for predicting CE CAZy class members per CAZyme classier, overlaying a density map.
Figure 6.15: Summary statistics of CAZyme classifiers performances of CE class classification, plotting the mean plus and minus the 95% confidence interval.
Figure 6.16: One dimensional scatter plot of the statistical parameters per test set for the classification of CE class members, overlaying a box plot
6.4.4.1 Specificity test
A one-way ANOVA was performed to determine if the mean specificity was statistically significantly different between the tools.
## Df Sum Sq Mean Sq F value Pr(>F)
## Prediction_tool 4 0.00031 0.0000764 0.212 0.932
## Residuals 375 0.13515 0.0003604The means are not statistically significantly different.
6.4.4.2 Sensitivity test
A one-way ANOVA was performed to determine if the mean sensitivity was statistically significantly different between the tools.
## Df Sum Sq Mean Sq F value Pr(>F)
## Prediction_tool 4 0.244 0.06105 6.886 2.34e-05 ***
## Residuals 375 3.324 0.00887
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1The means are statistically significantly different, therefore, use a post hoc Turkey HSD test to determine between which tools the means are significantly difference.
## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistic_value ~ Prediction_tool, data = ce_subset_sens.df)
##
## $Prediction_tool
## diff lwr upr
## dbCAN_4:HMMER-dbCAN_4 -2.536028e-02 -0.06722802 0.0165074735
## dbCAN_4:DIAMOND-dbCAN_4 -2.767335e-03 -0.04463508 0.0391004142
## dbCAN_4:dbCAN-sub-dbCAN_4 -2.793442e-03 -0.04466119 0.0390743073
## CUPP-dbCAN_4 -6.682331e-02 -0.10869106 -0.0249555590
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 2.259294e-02 -0.01927481 0.0644606899
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 2.256683e-02 -0.01930092 0.0644345830
## CUPP-dbCAN_4:HMMER -4.146303e-02 -0.08333078 0.0004047166
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND -2.610693e-05 -0.04189386 0.0418416423
## CUPP-dbCAN_4:DIAMOND -6.405597e-02 -0.10592372 -0.0221882240
## CUPP-dbCAN_4:dbCAN-sub -6.402987e-02 -0.10589762 -0.0221621171
## p adj
## dbCAN_4:HMMER-dbCAN_4 0.4599070
## dbCAN_4:DIAMOND-dbCAN_4 0.9997583
## dbCAN_4:dbCAN-sub-dbCAN_4 0.9997492
## CUPP-dbCAN_4 0.0001529
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.5766881
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.5778015
## CUPP-dbCAN_4:HMMER 0.0536900
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND 1.0000000
## CUPP-dbCAN_4:DIAMOND 0.0003294
## CUPP-dbCAN_4:dbCAN-sub 0.00033176.4.4.3 Precision test
A one-way ANOVA was performed to determine if the mean precision was statistically significantly different between the tools.
## Df Sum Sq Mean Sq F value Pr(>F)
## Prediction_tool 4 0.009 0.002326 0.161 0.958
## Residuals 375 5.425 0.014466The means are not statistically significantly different.
6.4.4.4 F1 test
A one-way ANOVA was performed to determine if the mean F1-scores was statistically significantly different between the tools.
## Df Sum Sq Mean Sq F value Pr(>F)
## Prediction_tool 4 0.072 0.01812 1.809 0.126
## Residuals 375 3.757 0.01002The means are statistically significantly different, therefore, use a post hoc Turkey HSD test to determine between which tools the means are significantly difference.
## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistic_value ~ Prediction_tool, data = ce_subset_f1.df)
##
## $Prediction_tool
## diff lwr upr
## dbCAN_4:HMMER-dbCAN_4 -0.015078708 -0.05958645 0.029429035
## dbCAN_4:DIAMOND-dbCAN_4 -0.013114916 -0.05762266 0.031392827
## dbCAN_4:dbCAN-sub-dbCAN_4 -0.002078856 -0.04658660 0.042428887
## CUPP-dbCAN_4 -0.038773734 -0.08328148 0.005734009
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.001963792 -0.04254395 0.046471535
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.012999851 -0.03150789 0.057507594
## CUPP-dbCAN_4:HMMER -0.023695026 -0.06820277 0.020812716
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND 0.011036060 -0.03347168 0.055543803
## CUPP-dbCAN_4:DIAMOND -0.025658818 -0.07016656 0.018848925
## CUPP-dbCAN_4:dbCAN-sub -0.036694878 -0.08120262 0.007812865
## p adj
## dbCAN_4:HMMER-dbCAN_4 0.8856855
## dbCAN_4:DIAMOND-dbCAN_4 0.9281829
## dbCAN_4:dbCAN-sub-dbCAN_4 0.9999393
## CUPP-dbCAN_4 0.1208366
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.9999516
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.9303152
## CUPP-dbCAN_4:HMMER 0.5896207
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND 0.9607571
## CUPP-dbCAN_4:DIAMOND 0.5110137
## CUPP-dbCAN_4:dbCAN-sub 0.16042746.4.4.5 Accuracy test
A one-way ANOVA was performed to determine if the mean accuracy was statistically significantly different between the tools.
## Df Sum Sq Mean Sq F value Pr(>F)
## Prediction_tool 4 0.00088 0.0002209 0.642 0.633
## Residuals 375 0.12908 0.0003442The means are statistically significantly different, therefore, use a post hoc Turkey HSD test to determine between which tools the means are significantly difference.
## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistic_value ~ Prediction_tool, data = ce_subset_acc.df)
##
## $Prediction_tool
## diff lwr upr
## dbCAN_4:HMMER-dbCAN_4 -0.0014483522 -0.009698103 0.006801399
## dbCAN_4:DIAMOND-dbCAN_4 -0.0023678549 -0.010617606 0.005881896
## dbCAN_4:dbCAN-sub-dbCAN_4 -0.0004962847 -0.008746036 0.007753466
## CUPP-dbCAN_4 -0.0043042553 -0.012554006 0.003945496
## dbCAN_4:DIAMOND-dbCAN_4:HMMER -0.0009195026 -0.009169253 0.007330248
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.0009520675 -0.007297683 0.009201818
## CUPP-dbCAN_4:HMMER -0.0028559031 -0.011105654 0.005393848
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND 0.0018715701 -0.006378181 0.010121321
## CUPP-dbCAN_4:DIAMOND -0.0019364005 -0.010186151 0.006313350
## CUPP-dbCAN_4:dbCAN-sub -0.0038079706 -0.012057721 0.004441780
## p adj
## dbCAN_4:HMMER-dbCAN_4 0.9890374
## dbCAN_4:DIAMOND-dbCAN_4 0.9343741
## dbCAN_4:dbCAN-sub-dbCAN_4 0.9998337
## CUPP-dbCAN_4 0.6085588
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.9981007
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.9978239
## CUPP-dbCAN_4:HMMER 0.8774452
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND 0.9715409
## CUPP-dbCAN_4:DIAMOND 0.9677918
## CUPP-dbCAN_4:dbCAN-sub 0.71270476.4.5 AA class classification
| Prediction_tool | Spec Mean | Spec Standard Deviation | Spec CI Lower | Spec CI Upper | Sens Mean | Sens Standard Deviation | Sens CI Lower | Sens CI Upper | Prec Mean | Prec Standard Deviation | Prec CI Lower | Prec CI Upper | F1-score Mean | F1-score Standard Deviation | F1-score CI Lower | F1-score CI Upper | Acc Mean | Acc Standard Deviation | Acc CI Lower | Acc CI Upper |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CUPP | 0.9919 | 0.0175 | 0.9868 | 0.9970 | 0.9047 | 0.1300 | 0.8670 | 0.9425 | 0.9184 | 0.1697 | 0.8691 | 0.9677 | 0.9011 | 0.1376 | 0.8611 | 0.9410 | 0.9841 | 0.0215 | 0.9778 | 0.9903 |
| dbCAN_4 | 0.9907 | 0.0201 | 0.9848 | 0.9965 | 0.9937 | 0.0258 | 0.9862 | 1.0012 | 0.9198 | 0.1610 | 0.8731 | 0.9666 | 0.9464 | 0.1085 | 0.9149 | 0.9779 | 0.9907 | 0.0188 | 0.9853 | 0.9962 |
| dbCAN_4:dbCAN-sub | 0.9905 | 0.0202 | 0.9846 | 0.9963 | 0.9892 | 0.0331 | 0.9796 | 0.9988 | 0.9177 | 0.1620 | 0.8707 | 0.9648 | 0.9430 | 0.1090 | 0.9113 | 0.9746 | 0.9902 | 0.0189 | 0.9847 | 0.9956 |
| dbCAN_4:DIAMOND | 0.9903 | 0.0219 | 0.9839 | 0.9966 | 0.9700 | 0.0952 | 0.9423 | 0.9976 | 0.9196 | 0.1697 | 0.8703 | 0.9689 | 0.9306 | 0.1226 | 0.8950 | 0.9662 | 0.9897 | 0.0198 | 0.9840 | 0.9954 |
| dbCAN_4:HMMER | 0.9907 | 0.0202 | 0.9848 | 0.9965 | 0.9880 | 0.0393 | 0.9766 | 0.9994 | 0.9192 | 0.1624 | 0.8720 | 0.9664 | 0.9434 | 0.1112 | 0.9111 | 0.9757 | 0.9901 | 0.0196 | 0.9844 | 0.9958 |
Figure 6.17: Scatter plot of sensitivity against specificity for predicting AA CAZy class members per CAZyme classier, overlaying a density map.
Figure 6.18: Summary statistics of CAZyme classifiers performances of AA class classification, plotting the mean plus and minus the 95% confidence interval.
Figure 6.19: One dimensional scatter plot of the statistical parameters per test set for the classification of AA class members, overlaying a box plot
6.4.5.1 Specificity test
A one-way ANOVA was performed to determine if the mean specificity was statistically significantly different between the tools.
## Df Sum Sq Mean Sq F value Pr(>F)
## Prediction_tool 4 0.00008 0.0000205 0.051 0.995
## Residuals 235 0.09429 0.0004012The means are statistically significantly different.
6.4.5.2 Sensitivity test
A one-way ANOVA was performed to determine if the mean sensitivity was statistically significantly different between the tools.
## Df Sum Sq Mean Sq F value Pr(>F)
## Prediction_tool 4 0.2644 0.06611 11.29 2.13e-08 ***
## Residuals 235 1.3758 0.00585
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1The means are statistically significantly different, therefore, use a post hoc Turkey HSD test to determine between which tools the means are significantly difference.
## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistic_value ~ Prediction_tool, data = aa_subset_sens.df)
##
## $Prediction_tool
## diff lwr upr
## dbCAN_4:HMMER-dbCAN_4 -0.005696849 -0.04863256 0.03723886
## dbCAN_4:DIAMOND-dbCAN_4 -0.023695055 -0.06663076 0.01924065
## dbCAN_4:dbCAN-sub-dbCAN_4 -0.004498106 -0.04743381 0.03843760
## CUPP-dbCAN_4 -0.088955200 -0.13189091 -0.04601949
## dbCAN_4:DIAMOND-dbCAN_4:HMMER -0.017998205 -0.06093391 0.02493750
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.001198743 -0.04173697 0.04413445
## CUPP-dbCAN_4:HMMER -0.083258350 -0.12619406 -0.04032264
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND 0.019196949 -0.02373876 0.06213266
## CUPP-dbCAN_4:DIAMOND -0.065260145 -0.10819585 -0.02232444
## CUPP-dbCAN_4:dbCAN-sub -0.084457094 -0.12739280 -0.04152139
## p adj
## dbCAN_4:HMMER-dbCAN_4 0.9962016
## dbCAN_4:DIAMOND-dbCAN_4 0.5523767
## dbCAN_4:dbCAN-sub-dbCAN_4 0.9984885
## CUPP-dbCAN_4 0.0000004
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.7782979
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.9999921
## CUPP-dbCAN_4:HMMER 0.0000023
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND 0.7343774
## CUPP-dbCAN_4:DIAMOND 0.0003960
## CUPP-dbCAN_4:dbCAN-sub 0.00000166.4.5.3 Precision test
A one-way ANOVA was performed to determine if the mean precision was statistically significantly different between the tools.
## Df Sum Sq Mean Sq F value Pr(>F)
## Prediction_tool 4 0.0 0.000037 0.001 1
## Residuals 235 6.4 0.027234The means are not statistically significantly different.
6.4.5.4 F1 test
A one-way ANOVA was performed to determine if the mean F1-scores was statistically significantly different between the tools.
## Df Sum Sq Mean Sq F value Pr(>F)
## Prediction_tool 4 0.068 0.01698 1.213 0.306
## Residuals 235 3.289 0.01400The means are statistically significantly different, therefore, use a post hoc Turkey HSD test to determine between which tools the means are significantly difference.
## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistic_value ~ Prediction_tool, data = aa_subset_f1.df)
##
## $Prediction_tool
## diff lwr upr
## dbCAN_4:HMMER-dbCAN_4 -0.0030006105 -0.06938731 0.06338609
## dbCAN_4:DIAMOND-dbCAN_4 -0.0158054434 -0.08219215 0.05058126
## dbCAN_4:dbCAN-sub-dbCAN_4 -0.0034594937 -0.06984620 0.06292721
## CUPP-dbCAN_4 -0.0453826990 -0.11176940 0.02100400
## dbCAN_4:DIAMOND-dbCAN_4:HMMER -0.0128048329 -0.07919154 0.05358187
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER -0.0004588832 -0.06684559 0.06592782
## CUPP-dbCAN_4:HMMER -0.0423820885 -0.10876879 0.02400461
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND 0.0123459497 -0.05404075 0.07873265
## CUPP-dbCAN_4:DIAMOND -0.0295772556 -0.09596396 0.03680945
## CUPP-dbCAN_4:dbCAN-sub -0.0419232053 -0.10830991 0.02446350
## p adj
## dbCAN_4:HMMER-dbCAN_4 0.9999459
## dbCAN_4:DIAMOND-dbCAN_4 0.9656671
## dbCAN_4:dbCAN-sub-dbCAN_4 0.9999047
## CUPP-dbCAN_4 0.3313673
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.9841703
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 1.0000000
## CUPP-dbCAN_4:HMMER 0.4025012
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND 0.9861940
## CUPP-dbCAN_4:DIAMOND 0.7369387
## CUPP-dbCAN_4:dbCAN-sub 0.41392506.4.5.5 Accuracy test
A one-way ANOVA was performed to determine if the mean accuracy was statistically significantly different between the tools.
## Df Sum Sq Mean Sq F value Pr(>F)
## Prediction_tool 4 0.00145 0.0003627 0.931 0.446
## Residuals 235 0.09154 0.0003895The means are statistically significantly different.
6.4.6 CBM class classification
| Prediction_tool | Spec Mean | Spec Standard Deviation | Spec CI Lower | Spec CI Upper | Sens Mean | Sens Standard Deviation | Sens CI Lower | Sens CI Upper | Prec Mean | Prec Standard Deviation | Prec CI Lower | Prec CI Upper | F1-score Mean | F1-score Standard Deviation | F1-score CI Lower | F1-score CI Upper | Acc Mean | Acc Standard Deviation | Acc CI Lower | Acc CI Upper |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CUPP | 1.0000 | 0.0000 | 1.0000 | 1.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.8851 | 0.0851 | 0.8662 | 0.9040 |
| dbCAN_4 | 0.9951 | 0.0103 | 0.9928 | 0.9974 | 0.7995 | 0.1921 | 0.7567 | 0.8422 | 0.9562 | 0.0919 | 0.9358 | 0.9767 | 0.8547 | 0.1392 | 0.8237 | 0.8857 | 0.9763 | 0.0207 | 0.9717 | 0.9809 |
| dbCAN_4:dbCAN-sub | 0.9927 | 0.0129 | 0.9898 | 0.9955 | 0.8193 | 0.1995 | 0.7749 | 0.8637 | 0.9376 | 0.1151 | 0.9120 | 0.9632 | 0.8576 | 0.1492 | 0.8244 | 0.8908 | 0.9761 | 0.0244 | 0.9707 | 0.9816 |
| dbCAN_4:DIAMOND | 0.9938 | 0.0146 | 0.9906 | 0.9970 | 0.8773 | 0.1695 | 0.8396 | 0.9151 | 0.9571 | 0.1273 | 0.9288 | 0.9854 | 0.9072 | 0.1362 | 0.8768 | 0.9375 | 0.9830 | 0.0182 | 0.9790 | 0.9870 |
| dbCAN_4:HMMER | 0.9958 | 0.0097 | 0.9937 | 0.9980 | 0.4740 | 0.2360 | 0.4215 | 0.5266 | 0.9184 | 0.1999 | 0.8739 | 0.9629 | 0.5954 | 0.2202 | 0.5464 | 0.6444 | 0.9436 | 0.0300 | 0.9370 | 0.9503 |
Figure 6.20: Scatter plot of sensitivity against specificity for predicting CBM CAZy class members per CAZyme classier, overlaying a density map.
Figure 6.21: Summary statistics of CAZyme classifiers performances of CBM class classification, plotting the mean plus and minus the 95% confidence interval.
Figure 6.22: One dimensional scatter plot of the statistical parameters per test set for the classification of CBM class members, overlaying a box plot
6.4.6.1 Specificity test
A one-way ANOVA was performed to determine if the mean specificity was statistically significantly different between the tools.
## Df Sum Sq Mean Sq F value Pr(>F)
## Prediction_tool 4 0.00251 0.0006275 5.41 3e-04 ***
## Residuals 395 0.04582 0.0001160
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1The means are statistically significantly different, therefore, use a post hoc Turkey HSD test to determine between which tools the means are significantly difference.
## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistic_value ~ Prediction_tool, data = cbm_subset_spec.df)
##
## $Prediction_tool
## diff lwr upr
## dbCAN_4:HMMER-dbCAN_4 0.0006932115 -0.0039734260 0.005359849
## dbCAN_4:DIAMOND-dbCAN_4 -0.0013130114 -0.0059796489 0.003353626
## dbCAN_4:dbCAN-sub-dbCAN_4 -0.0024478171 -0.0071144546 0.002218820
## CUPP-dbCAN_4 0.0048825721 0.0002159346 0.009549210
## dbCAN_4:DIAMOND-dbCAN_4:HMMER -0.0020062230 -0.0066728605 0.002660415
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER -0.0031410287 -0.0078076661 0.001525609
## CUPP-dbCAN_4:HMMER 0.0041893606 -0.0004772769 0.008855998
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND -0.0011348057 -0.0058014432 0.003531832
## CUPP-dbCAN_4:DIAMOND 0.0061955836 0.0015289461 0.010862221
## CUPP-dbCAN_4:dbCAN-sub 0.0073303893 0.0026637518 0.011997027
## p adj
## dbCAN_4:HMMER-dbCAN_4 0.9942139
## dbCAN_4:DIAMOND-dbCAN_4 0.9387979
## dbCAN_4:dbCAN-sub-dbCAN_4 0.6038005
## CUPP-dbCAN_4 0.0351653
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.7639319
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.3494979
## CUPP-dbCAN_4:HMMER 0.1019846
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND 0.9634447
## CUPP-dbCAN_4:DIAMOND 0.0028592
## CUPP-dbCAN_4:dbCAN-sub 0.00020426.4.6.2 Sensitivity test
A one-way ANOVA was performed to determine if the mean sensitivity was statistically significantly different between the tools.
## Df Sum Sq Mean Sq F value Pr(>F)
## Prediction_tool 4 43.24 10.810 335.4 <2e-16 ***
## Residuals 395 12.73 0.032
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1The means are statistically significantly different, therefore, use a post hoc Turkey HSD test to determine between which tools the means are significantly difference.
## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistic_value ~ Prediction_tool, data = cbm_subset_sens.df)
##
## $Prediction_tool
## diff lwr upr
## dbCAN_4:HMMER-dbCAN_4 -0.32544431 -4.032310e-01 -0.24765759
## dbCAN_4:DIAMOND-dbCAN_4 0.07784943 6.271769e-05 0.15563614
## dbCAN_4:dbCAN-sub-dbCAN_4 0.01983829 -5.794842e-02 0.09762500
## CUPP-dbCAN_4 -0.79948442 -8.772711e-01 -0.72169771
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.40329374 3.255070e-01 0.48108045
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.34528260 2.674959e-01 0.42306931
## CUPP-dbCAN_4:HMMER -0.47404012 -5.518268e-01 -0.39625340
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND -0.05801114 -1.357979e-01 0.01977557
## CUPP-dbCAN_4:DIAMOND -0.87733385 -9.551206e-01 -0.79954714
## CUPP-dbCAN_4:dbCAN-sub -0.81932271 -8.971094e-01 -0.74153600
## p adj
## dbCAN_4:HMMER-dbCAN_4 0.0000000
## dbCAN_4:DIAMOND-dbCAN_4 0.0497020
## dbCAN_4:dbCAN-sub-dbCAN_4 0.9566574
## CUPP-dbCAN_4 0.0000000
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.0000000
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.0000000
## CUPP-dbCAN_4:HMMER 0.0000000
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND 0.2471706
## CUPP-dbCAN_4:DIAMOND 0.0000000
## CUPP-dbCAN_4:dbCAN-sub 0.00000006.4.6.3 Precision test
A one-way ANOVA was performed to determine if the mean precision was statistically significantly different between the tools.
## Df Sum Sq Mean Sq F value Pr(>F)
## Prediction_tool 4 56.91 14.228 913.6 <2e-16 ***
## Residuals 395 6.15 0.016
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1The means are statistically significantly different.
## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistic_value ~ Prediction_tool, data = cbm_subset_prec.df)
##
## $Prediction_tool
## diff lwr upr
## dbCAN_4:HMMER-dbCAN_4 -0.0378524537 -0.09192488 0.01621997
## dbCAN_4:DIAMOND-dbCAN_4 0.0008595429 -0.05321288 0.05493197
## dbCAN_4:dbCAN-sub-dbCAN_4 -0.0186543961 -0.07272682 0.03541803
## CUPP-dbCAN_4 -0.9562480280 -1.01032045 -0.90217561
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.0387119966 -0.01536043 0.09278442
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.0191980577 -0.03487436 0.07327048
## CUPP-dbCAN_4:HMMER -0.9183955743 -0.97246800 -0.86432315
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND -0.0195139389 -0.07358636 0.03455848
## CUPP-dbCAN_4:DIAMOND -0.9571075709 -1.01117999 -0.90303515
## CUPP-dbCAN_4:dbCAN-sub -0.9375936320 -0.99166605 -0.88352121
## p adj
## dbCAN_4:HMMER-dbCAN_4 0.3092108
## dbCAN_4:DIAMOND-dbCAN_4 0.9999992
## dbCAN_4:dbCAN-sub-dbCAN_4 0.8789009
## CUPP-dbCAN_4 0.0000000
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.2867122
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.8672654
## CUPP-dbCAN_4:HMMER 0.0000000
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND 0.8602420
## CUPP-dbCAN_4:DIAMOND 0.0000000
## CUPP-dbCAN_4:dbCAN-sub 0.00000006.4.6.4 F1 test
A one-way ANOVA was performed to determine if the mean F1-scores was statistically significantly different between the tools.
## Df Sum Sq Mean Sq F value Pr(>F)
## Prediction_tool 4 46.11 11.528 530.4 <2e-16 ***
## Residuals 395 8.58 0.022
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1The means are statistically significantly different, therefore, use a post hoc Turkey HSD test to determine between which tools the means are significantly difference.
## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistic_value ~ Prediction_tool, data = cbm_subset_f1.df)
##
## $Prediction_tool
## diff lwr upr
## dbCAN_4:HMMER-dbCAN_4 -0.259342537 -0.32322042 -0.19546465
## dbCAN_4:DIAMOND-dbCAN_4 0.052444317 -0.01143357 0.11632220
## dbCAN_4:dbCAN-sub-dbCAN_4 0.002905998 -0.06097188 0.06678388
## CUPP-dbCAN_4 -0.854719675 -0.91859756 -0.79084179
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.311786853 0.24790897 0.37566474
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.262248534 0.19837065 0.32612642
## CUPP-dbCAN_4:HMMER -0.595377139 -0.65925502 -0.53149926
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND -0.049538319 -0.11341620 0.01433956
## CUPP-dbCAN_4:DIAMOND -0.907163992 -0.97104187 -0.84328611
## CUPP-dbCAN_4:dbCAN-sub -0.857625673 -0.92150356 -0.79374779
## p adj
## dbCAN_4:HMMER-dbCAN_4 0.0000000
## dbCAN_4:DIAMOND-dbCAN_4 0.1637675
## dbCAN_4:dbCAN-sub-dbCAN_4 0.9999454
## CUPP-dbCAN_4 0.0000000
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.0000000
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.0000000
## CUPP-dbCAN_4:HMMER 0.0000000
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND 0.2113918
## CUPP-dbCAN_4:DIAMOND 0.0000000
## CUPP-dbCAN_4:dbCAN-sub 0.00000006.4.6.5 Accuracy test
A one-way ANOVA was performed to determine if the mean accuracy was statistically significantly different between the tools.
## Df Sum Sq Mean Sq F value Pr(>F)
## Prediction_tool 4 0.5340 0.1335 70.33 <2e-16 ***
## Residuals 395 0.7498 0.0019
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1The means are statistically significantly different, therefore, use a post hoc Turkey HSD test to determine between which tools the means are significantly difference.
## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistic_value ~ Prediction_tool, data = cbm_subset_acc.df)
##
## $Prediction_tool
## diff lwr upr
## dbCAN_4:HMMER-dbCAN_4 -0.0326706710 -0.05154899 -0.01379235
## dbCAN_4:DIAMOND-dbCAN_4 0.0066847597 -0.01219356 0.02556308
## dbCAN_4:dbCAN-sub-dbCAN_4 -0.0001608712 -0.01903919 0.01871745
## CUPP-dbCAN_4 -0.0912001172 -0.11007844 -0.07232179
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.0393554307 0.02047711 0.05823375
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.0325097998 0.01363148 0.05138812
## CUPP-dbCAN_4:HMMER -0.0585294462 -0.07740777 -0.03965112
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND -0.0068456309 -0.02572395 0.01203269
## CUPP-dbCAN_4:DIAMOND -0.0978848769 -0.11676320 -0.07900655
## CUPP-dbCAN_4:dbCAN-sub -0.0910392460 -0.10991757 -0.07216092
## p adj
## dbCAN_4:HMMER-dbCAN_4 0.0000290
## dbCAN_4:DIAMOND-dbCAN_4 0.8683851
## dbCAN_4:dbCAN-sub-dbCAN_4 0.9999999
## CUPP-dbCAN_4 0.0000000
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.0000002
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.0000323
## CUPP-dbCAN_4:HMMER 0.0000000
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND 0.8581215
## CUPP-dbCAN_4:DIAMOND 0.0000000
## CUPP-dbCAN_4:dbCAN-sub 0.00000006.5 Performance per statistic
Instead of facet wrapping the plots by statistic and producing a plot per CAZy class, we can produce a plot per statistic (sensitivity, precision, etc.) and facet wrap by CAZy class to facilitate comparing between CAZy classes, and evaluting the performance statistic by statistic.
For each statistical parameter, perform a two-way ANOVA to test for statistically significant differences between the CAZy classes, prediction tools and the interaction of the two. If a significant difference is found, follow up with a post hoc test to determine between which tools and classes there is a statistically significant difference.
6.5.1 CAZy class Specificity
Two-way ANOVA to test for differences between the CAZy classes and prediction tools.
## Df Sum Sq Mean Sq F value Pr(>F)
## CAZy_class 5 0.0172 0.003444 4.874 0.000195 ***
## Prediction_tool 4 0.0032 0.000794 1.124 0.343490
## CAZy_class:Prediction_tool 20 0.0030 0.000149 0.211 0.999926
## Residuals 2025 1.4311 0.000707
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1Statistically significant difference was detected, so follow up with a Tukey test to determine if there are differences between specific groups.
## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistic_value ~ CAZy_class * Prediction_tool, data = class_subset_spec.df)
##
## $`CAZy_class:Prediction_tool`
## diff lwr
## CBM:dbCAN_4-AA:dbCAN_4 4.448137e-03 -0.013772495
## CE:dbCAN_4-AA:dbCAN_4 4.643185e-03 -0.013756377
## GH:dbCAN_4-AA:dbCAN_4 1.993153e-03 -0.016227479
## GT:dbCAN_4-AA:dbCAN_4 -7.116511e-04 -0.018932283
## PL:dbCAN_4-AA:dbCAN_4 8.695503e-03 -0.011783854
## AA:dbCAN_4:HMMER-AA:dbCAN_4 -1.427382e-05 -0.020385560
## CBM:dbCAN_4:HMMER-AA:dbCAN_4 5.141348e-03 -0.013079284
## CE:dbCAN_4:HMMER-AA:dbCAN_4 4.637473e-03 -0.013762089
## GH:dbCAN_4:HMMER-AA:dbCAN_4 3.191298e-03 -0.015029334
## GT:dbCAN_4:HMMER-AA:dbCAN_4 -2.758033e-04 -0.018496435
## PL:dbCAN_4:HMMER-AA:dbCAN_4 8.689951e-03 -0.011789406
## AA:dbCAN_4:DIAMOND-AA:dbCAN_4 -4.113656e-04 -0.020782652
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4 3.135126e-03 -0.015085507
## CE:dbCAN_4:DIAMOND-AA:dbCAN_4 2.413458e-03 -0.015986104
## GH:dbCAN_4:DIAMOND-AA:dbCAN_4 -4.228197e-03 -0.022448829
## GT:dbCAN_4:DIAMOND-AA:dbCAN_4 -1.333525e-03 -0.019554157
## PL:dbCAN_4:DIAMOND-AA:dbCAN_4 8.235541e-03 -0.012243816
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4 -2.114373e-04 -0.020582723
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4 2.000320e-03 -0.016220312
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4 4.514486e-03 -0.013885076
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4 1.734505e-03 -0.016486127
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4 -7.006013e-04 -0.018921233
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4 8.698967e-03 -0.011780390
## AA:CUPP-AA:dbCAN_4 1.252955e-03 -0.019118331
## CBM:CUPP-AA:dbCAN_4 9.330709e-03 -0.008889923
## CE:CUPP-AA:dbCAN_4 4.785384e-03 -0.013614178
## GH:CUPP-AA:dbCAN_4 2.613610e-03 -0.015607022
## GT:CUPP-AA:dbCAN_4 1.422603e-03 -0.016798029
## PL:CUPP-AA:dbCAN_4 8.933291e-03 -0.011546066
## CE:dbCAN_4-CBM:dbCAN_4 1.950480e-04 -0.015790759
## GH:dbCAN_4-CBM:dbCAN_4 -2.454984e-03 -0.018234514
## GT:dbCAN_4-CBM:dbCAN_4 -5.159788e-03 -0.020939318
## PL:dbCAN_4-CBM:dbCAN_4 4.247366e-03 -0.014094013
## AA:dbCAN_4:HMMER-CBM:dbCAN_4 -4.462411e-03 -0.022683043
## CBM:dbCAN_4:HMMER-CBM:dbCAN_4 6.932115e-04 -0.015086319
## CE:dbCAN_4:HMMER-CBM:dbCAN_4 1.893364e-04 -0.015796471
## GH:dbCAN_4:HMMER-CBM:dbCAN_4 -1.256839e-03 -0.017036369
## GT:dbCAN_4:HMMER-CBM:dbCAN_4 -4.723940e-03 -0.020503471
## PL:dbCAN_4:HMMER-CBM:dbCAN_4 4.241814e-03 -0.014099566
## AA:dbCAN_4:DIAMOND-CBM:dbCAN_4 -4.859503e-03 -0.023080135
## CBM:dbCAN_4:DIAMOND-CBM:dbCAN_4 -1.313011e-03 -0.017092542
## CE:dbCAN_4:DIAMOND-CBM:dbCAN_4 -2.034679e-03 -0.018020486
## GH:dbCAN_4:DIAMOND-CBM:dbCAN_4 -8.676334e-03 -0.024455864
## GT:dbCAN_4:DIAMOND-CBM:dbCAN_4 -5.781662e-03 -0.021561192
## PL:dbCAN_4:DIAMOND-CBM:dbCAN_4 3.787404e-03 -0.014553976
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 -4.659574e-03 -0.022880206
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 -2.447817e-03 -0.018227347
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 6.634923e-05 -0.015919458
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 -2.713632e-03 -0.018493162
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 -5.148738e-03 -0.020928269
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 4.250830e-03 -0.014090550
## AA:CUPP-CBM:dbCAN_4 -3.195182e-03 -0.021415814
## CBM:CUPP-CBM:dbCAN_4 4.882572e-03 -0.010896958
## CE:CUPP-CBM:dbCAN_4 3.372471e-04 -0.015648560
## GH:CUPP-CBM:dbCAN_4 -1.834527e-03 -0.017614057
## GT:CUPP-CBM:dbCAN_4 -3.025534e-03 -0.018805064
## PL:CUPP-CBM:dbCAN_4 4.485154e-03 -0.013856226
## GH:dbCAN_4-CE:dbCAN_4 -2.650032e-03 -0.018635839
## GT:dbCAN_4-CE:dbCAN_4 -5.354836e-03 -0.021340643
## PL:dbCAN_4-CE:dbCAN_4 4.052318e-03 -0.014466825
## AA:dbCAN_4:HMMER-CE:dbCAN_4 -4.657459e-03 -0.023057021
## CBM:dbCAN_4:HMMER-CE:dbCAN_4 4.981636e-04 -0.015487644
## CE:dbCAN_4:HMMER-CE:dbCAN_4 -5.711512e-06 -0.016195168
## GH:dbCAN_4:HMMER-CE:dbCAN_4 -1.451887e-03 -0.017437695
## GT:dbCAN_4:HMMER-CE:dbCAN_4 -4.918988e-03 -0.020904796
## PL:dbCAN_4:HMMER-CE:dbCAN_4 4.046766e-03 -0.014472378
## AA:dbCAN_4:DIAMOND-CE:dbCAN_4 -5.054550e-03 -0.023454113
## CBM:dbCAN_4:DIAMOND-CE:dbCAN_4 -1.508059e-03 -0.017493867
## CE:dbCAN_4:DIAMOND-CE:dbCAN_4 -2.229727e-03 -0.018419183
## GH:dbCAN_4:DIAMOND-CE:dbCAN_4 -8.871382e-03 -0.024857189
## GT:dbCAN_4:DIAMOND-CE:dbCAN_4 -5.976710e-03 -0.021962517
## PL:dbCAN_4:DIAMOND-CE:dbCAN_4 3.592356e-03 -0.014926787
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4 -4.854622e-03 -0.023254185
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4 -2.642865e-03 -0.018628672
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4 -1.286987e-04 -0.016318155
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4 -2.908679e-03 -0.018894487
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4 -5.343786e-03 -0.021329594
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4 4.055782e-03 -0.014463361
## AA:CUPP-CE:dbCAN_4 -3.390230e-03 -0.021789792
## CBM:CUPP-CE:dbCAN_4 4.687524e-03 -0.011298283
## CE:CUPP-CE:dbCAN_4 1.421991e-04 -0.016047257
## GH:CUPP-CE:dbCAN_4 -2.029575e-03 -0.018015382
## GT:CUPP-CE:dbCAN_4 -3.220582e-03 -0.019206389
## PL:CUPP-CE:dbCAN_4 4.290106e-03 -0.014229038
## GT:dbCAN_4-GH:dbCAN_4 -2.704804e-03 -0.018484334
## PL:dbCAN_4-GH:dbCAN_4 6.702350e-03 -0.011639029
## AA:dbCAN_4:HMMER-GH:dbCAN_4 -2.007427e-03 -0.020228059
## CBM:dbCAN_4:HMMER-GH:dbCAN_4 3.148195e-03 -0.012631335
## CE:dbCAN_4:HMMER-GH:dbCAN_4 2.644320e-03 -0.013341487
## GH:dbCAN_4:HMMER-GH:dbCAN_4 1.198145e-03 -0.014581386
## GT:dbCAN_4:HMMER-GH:dbCAN_4 -2.268956e-03 -0.018048487
## PL:dbCAN_4:HMMER-GH:dbCAN_4 6.696798e-03 -0.011644582
## AA:dbCAN_4:DIAMOND-GH:dbCAN_4 -2.404519e-03 -0.020625151
## CBM:dbCAN_4:DIAMOND-GH:dbCAN_4 1.141972e-03 -0.014637558
## CE:dbCAN_4:DIAMOND-GH:dbCAN_4 4.203050e-04 -0.015565502
## GH:dbCAN_4:DIAMOND-GH:dbCAN_4 -6.221350e-03 -0.022000880
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4 -3.326678e-03 -0.019106208
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4 6.242388e-03 -0.012098992
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4 -2.204590e-03 -0.020425222
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4 7.166795e-06 -0.015772363
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4 2.521333e-03 -0.013464474
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4 -2.586476e-04 -0.016038178
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4 -2.693754e-03 -0.018473285
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4 6.705814e-03 -0.011635566
## AA:CUPP-GH:dbCAN_4 -7.401982e-04 -0.018960830
## CBM:CUPP-GH:dbCAN_4 7.337556e-03 -0.008441974
## CE:CUPP-GH:dbCAN_4 2.792231e-03 -0.013193576
## GH:CUPP-GH:dbCAN_4 6.204571e-04 -0.015159073
## GT:CUPP-GH:dbCAN_4 -5.705499e-04 -0.016350080
## PL:CUPP-GH:dbCAN_4 6.940138e-03 -0.011401242
## PL:dbCAN_4-GT:dbCAN_4 9.407154e-03 -0.008934225
## AA:dbCAN_4:HMMER-GT:dbCAN_4 6.973773e-04 -0.017523255
## CBM:dbCAN_4:HMMER-GT:dbCAN_4 5.853000e-03 -0.009926531
## CE:dbCAN_4:HMMER-GT:dbCAN_4 5.349124e-03 -0.010636683
## GH:dbCAN_4:HMMER-GT:dbCAN_4 3.902949e-03 -0.011876581
## GT:dbCAN_4:HMMER-GT:dbCAN_4 4.358478e-04 -0.015343682
## PL:dbCAN_4:HMMER-GT:dbCAN_4 9.401602e-03 -0.008939778
## AA:dbCAN_4:DIAMOND-GT:dbCAN_4 3.002855e-04 -0.017920347
## CBM:dbCAN_4:DIAMOND-GT:dbCAN_4 3.846777e-03 -0.011932754
## CE:dbCAN_4:DIAMOND-GT:dbCAN_4 3.125109e-03 -0.012860698
## GH:dbCAN_4:DIAMOND-GT:dbCAN_4 -3.516546e-03 -0.019296076
## GT:dbCAN_4:DIAMOND-GT:dbCAN_4 -6.218739e-04 -0.016401404
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4 8.947192e-03 -0.009394188
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4 5.002138e-04 -0.017720418
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4 2.711971e-03 -0.013067559
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4 5.226137e-03 -0.010759670
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4 2.446157e-03 -0.013333374
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4 1.104977e-05 -0.015768480
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4 9.410618e-03 -0.008930762
## AA:CUPP-GT:dbCAN_4 1.964606e-03 -0.016256026
## CBM:CUPP-GT:dbCAN_4 1.004236e-02 -0.005737170
## CE:CUPP-GT:dbCAN_4 5.497035e-03 -0.010488772
## GH:CUPP-GT:dbCAN_4 3.325261e-03 -0.012454269
## GT:CUPP-GT:dbCAN_4 2.134254e-03 -0.013645276
## PL:CUPP-GT:dbCAN_4 9.644942e-03 -0.008696438
## AA:dbCAN_4:HMMER-PL:dbCAN_4 -8.709777e-03 -0.029189134
## CBM:dbCAN_4:HMMER-PL:dbCAN_4 -3.554155e-03 -0.021895535
## CE:dbCAN_4:HMMER-PL:dbCAN_4 -4.058030e-03 -0.022577173
## GH:dbCAN_4:HMMER-PL:dbCAN_4 -5.504206e-03 -0.023845585
## GT:dbCAN_4:HMMER-PL:dbCAN_4 -8.971307e-03 -0.027312687
## PL:dbCAN_4:HMMER-PL:dbCAN_4 -5.552537e-06 -0.020592414
## AA:dbCAN_4:DIAMOND-PL:dbCAN_4 -9.106869e-03 -0.029586226
## CBM:dbCAN_4:DIAMOND-PL:dbCAN_4 -5.560378e-03 -0.023901758
## CE:dbCAN_4:DIAMOND-PL:dbCAN_4 -6.282045e-03 -0.024801189
## GH:dbCAN_4:DIAMOND-PL:dbCAN_4 -1.292370e-02 -0.031265080
## GT:dbCAN_4:DIAMOND-PL:dbCAN_4 -1.002903e-02 -0.028370408
## PL:dbCAN_4:DIAMOND-PL:dbCAN_4 -4.599624e-04 -0.021046824
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4 -8.906941e-03 -0.029386298
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4 -6.695184e-03 -0.025036563
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4 -4.181017e-03 -0.022700161
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4 -6.960998e-03 -0.025302378
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4 -9.396105e-03 -0.027737485
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4 3.463617e-06 -0.020583398
## AA:CUPP-PL:dbCAN_4 -7.442549e-03 -0.027921906
## CBM:CUPP-PL:dbCAN_4 6.352057e-04 -0.017706174
## CE:CUPP-PL:dbCAN_4 -3.910119e-03 -0.022429263
## GH:CUPP-PL:dbCAN_4 -6.081893e-03 -0.024423273
## GT:CUPP-PL:dbCAN_4 -7.272900e-03 -0.025614280
## PL:CUPP-PL:dbCAN_4 2.377874e-04 -0.020349074
## CBM:dbCAN_4:HMMER-AA:dbCAN_4:HMMER 5.155622e-03 -0.013065010
## CE:dbCAN_4:HMMER-AA:dbCAN_4:HMMER 4.651747e-03 -0.013747815
## GH:dbCAN_4:HMMER-AA:dbCAN_4:HMMER 3.205572e-03 -0.015015061
## GT:dbCAN_4:HMMER-AA:dbCAN_4:HMMER -2.615295e-04 -0.018482162
## PL:dbCAN_4:HMMER-AA:dbCAN_4:HMMER 8.704225e-03 -0.011775133
## AA:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER -3.970918e-04 -0.020768378
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 3.149399e-03 -0.015071233
## CE:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 2.427732e-03 -0.015971831
## GH:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER -4.213923e-03 -0.022434555
## GT:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER -1.319251e-03 -0.019539883
## PL:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 8.249815e-03 -0.012229542
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER -1.971635e-04 -0.020568449
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 2.014594e-03 -0.016206038
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 4.528760e-03 -0.013870802
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 1.748779e-03 -0.016471853
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER -6.863275e-04 -0.018906960
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 8.713241e-03 -0.011766116
## AA:CUPP-AA:dbCAN_4:HMMER 1.267229e-03 -0.019104057
## CBM:CUPP-AA:dbCAN_4:HMMER 9.344983e-03 -0.008875649
## CE:CUPP-AA:dbCAN_4:HMMER 4.799658e-03 -0.013599905
## GH:CUPP-AA:dbCAN_4:HMMER 2.627884e-03 -0.015592748
## GT:CUPP-AA:dbCAN_4:HMMER 1.436877e-03 -0.016783755
## PL:CUPP-AA:dbCAN_4:HMMER 8.947565e-03 -0.011531793
## CE:dbCAN_4:HMMER-CBM:dbCAN_4:HMMER -5.038751e-04 -0.016489682
## GH:dbCAN_4:HMMER-CBM:dbCAN_4:HMMER -1.950051e-03 -0.017729581
## GT:dbCAN_4:HMMER-CBM:dbCAN_4:HMMER -5.417152e-03 -0.021196682
## PL:dbCAN_4:HMMER-CBM:dbCAN_4:HMMER 3.548602e-03 -0.014792777
## AA:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER -5.552714e-03 -0.023773346
## CBM:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER -2.006223e-03 -0.017785753
## CE:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER -2.727890e-03 -0.018713698
## GH:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER -9.369545e-03 -0.025149075
## GT:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER -6.474873e-03 -0.022254404
## PL:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 3.094192e-03 -0.015247187
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER -5.352786e-03 -0.023573418
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER -3.141029e-03 -0.018920559
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER -6.268623e-04 -0.016612670
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER -3.406843e-03 -0.019186373
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER -5.841950e-03 -0.021621480
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 3.557619e-03 -0.014783761
## AA:CUPP-CBM:dbCAN_4:HMMER -3.888394e-03 -0.022109026
## CBM:CUPP-CBM:dbCAN_4:HMMER 4.189361e-03 -0.011590170
## CE:CUPP-CBM:dbCAN_4:HMMER -3.559645e-04 -0.016341772
## GH:CUPP-CBM:dbCAN_4:HMMER -2.527738e-03 -0.018307269
## GT:CUPP-CBM:dbCAN_4:HMMER -3.718745e-03 -0.019498276
## PL:CUPP-CBM:dbCAN_4:HMMER 3.791942e-03 -0.014549437
## GH:dbCAN_4:HMMER-CE:dbCAN_4:HMMER -1.446176e-03 -0.017431983
## GT:dbCAN_4:HMMER-CE:dbCAN_4:HMMER -4.913277e-03 -0.020899084
## PL:dbCAN_4:HMMER-CE:dbCAN_4:HMMER 4.052477e-03 -0.014466666
## AA:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER -5.048839e-03 -0.023448401
## CBM:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER -1.502348e-03 -0.017488155
## CE:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER -2.224015e-03 -0.018413472
## GH:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER -8.865670e-03 -0.024851477
## GT:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER -5.970998e-03 -0.021956806
## PL:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 3.598068e-03 -0.014921076
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER -4.848911e-03 -0.023248473
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER -2.637154e-03 -0.018622961
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER -1.229872e-04 -0.016312444
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER -2.902968e-03 -0.018888775
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER -5.338075e-03 -0.021323882
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 4.061494e-03 -0.014457650
## AA:CUPP-CE:dbCAN_4:HMMER -3.384519e-03 -0.021784081
## CBM:CUPP-CE:dbCAN_4:HMMER 4.693236e-03 -0.011292572
## CE:CUPP-CE:dbCAN_4:HMMER 1.479106e-04 -0.016041546
## GH:CUPP-CE:dbCAN_4:HMMER -2.023863e-03 -0.018009671
## GT:CUPP-CE:dbCAN_4:HMMER -3.214870e-03 -0.019200678
## PL:CUPP-CE:dbCAN_4:HMMER 4.295817e-03 -0.014223326
## GT:dbCAN_4:HMMER-GH:dbCAN_4:HMMER -3.467101e-03 -0.019246631
## PL:dbCAN_4:HMMER-GH:dbCAN_4:HMMER 5.498653e-03 -0.012842727
## AA:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER -3.602663e-03 -0.021823295
## CBM:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER -5.617222e-05 -0.015835702
## CE:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER -7.778397e-04 -0.016763647
## GH:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER -7.419494e-03 -0.023199025
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER -4.524823e-03 -0.020304353
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 5.044243e-03 -0.013297137
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER -3.402735e-03 -0.021623367
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER -1.190978e-03 -0.016970508
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 1.323188e-03 -0.014662619
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER -1.456792e-03 -0.017236323
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER -3.891899e-03 -0.019671429
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 5.507669e-03 -0.012833711
## AA:CUPP-GH:dbCAN_4:HMMER -1.938343e-03 -0.020158975
## CBM:CUPP-GH:dbCAN_4:HMMER 6.139411e-03 -0.009640119
## CE:CUPP-GH:dbCAN_4:HMMER 1.594086e-03 -0.014391721
## GH:CUPP-GH:dbCAN_4:HMMER -5.776876e-04 -0.016357218
## GT:CUPP-GH:dbCAN_4:HMMER -1.768695e-03 -0.017548225
## PL:CUPP-GH:dbCAN_4:HMMER 5.741993e-03 -0.012599387
## PL:dbCAN_4:HMMER-GT:dbCAN_4:HMMER 8.965754e-03 -0.009375626
## AA:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER -1.355623e-04 -0.018356194
## CBM:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 3.410929e-03 -0.012368601
## CE:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 2.689261e-03 -0.013296546
## GH:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER -3.952393e-03 -0.019731924
## GT:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER -1.057722e-03 -0.016837252
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 8.511344e-03 -0.009830036
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 6.436601e-05 -0.018156266
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 2.276123e-03 -0.013503407
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 4.790289e-03 -0.011195518
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 2.010309e-03 -0.013769222
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER -4.247980e-04 -0.016204328
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 8.974770e-03 -0.009366609
## AA:CUPP-GT:dbCAN_4:HMMER 1.528758e-03 -0.016691874
## CBM:CUPP-GT:dbCAN_4:HMMER 9.606512e-03 -0.006173018
## CE:CUPP-GT:dbCAN_4:HMMER 5.061187e-03 -0.010924620
## GH:CUPP-GT:dbCAN_4:HMMER 2.889413e-03 -0.012890117
## GT:CUPP-GT:dbCAN_4:HMMER 1.698406e-03 -0.014081124
## PL:CUPP-GT:dbCAN_4:HMMER 9.209094e-03 -0.009132286
## AA:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER -9.101316e-03 -0.029580674
## CBM:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER -5.554825e-03 -0.023896205
## CE:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER -6.276493e-03 -0.024795636
## GH:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER -1.291815e-02 -0.031259527
## GT:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER -1.002348e-02 -0.028364856
## PL:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER -4.544099e-04 -0.021041271
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER -8.901388e-03 -0.029380745
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER -6.689631e-03 -0.025031011
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER -4.175465e-03 -0.022694608
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER -6.955445e-03 -0.025296825
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER -9.390552e-03 -0.027731932
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 9.016154e-06 -0.020577845
## AA:CUPP-PL:dbCAN_4:HMMER -7.436996e-03 -0.027916353
## CBM:CUPP-PL:dbCAN_4:HMMER 6.407582e-04 -0.017700622
## CE:CUPP-PL:dbCAN_4:HMMER -3.904567e-03 -0.022423710
## GH:CUPP-PL:dbCAN_4:HMMER -6.076341e-03 -0.024417721
## GT:CUPP-PL:dbCAN_4:HMMER -7.267348e-03 -0.025608727
## PL:CUPP-PL:dbCAN_4:HMMER 2.433400e-04 -0.020343521
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND 3.546491e-03 -0.014674141
## CE:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND 2.824824e-03 -0.015574739
## GH:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND -3.816831e-03 -0.022037463
## GT:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND -9.221594e-04 -0.019142792
## PL:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND 8.646907e-03 -0.011832451
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 1.999283e-04 -0.020171358
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 2.411685e-03 -0.015808947
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 4.925852e-03 -0.013473711
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 2.145871e-03 -0.016074761
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND -2.892357e-04 -0.018509868
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 9.110333e-03 -0.011369025
## AA:CUPP-AA:dbCAN_4:DIAMOND 1.664320e-03 -0.018706966
## CBM:CUPP-AA:dbCAN_4:DIAMOND 9.742075e-03 -0.008478557
## CE:CUPP-AA:dbCAN_4:DIAMOND 5.196750e-03 -0.013202813
## GH:CUPP-AA:dbCAN_4:DIAMOND 3.024976e-03 -0.015195656
## GT:CUPP-AA:dbCAN_4:DIAMOND 1.833969e-03 -0.016386663
## PL:CUPP-AA:dbCAN_4:DIAMOND 9.344656e-03 -0.011134701
## CE:dbCAN_4:DIAMOND-CBM:dbCAN_4:DIAMOND -7.216675e-04 -0.016707475
## GH:dbCAN_4:DIAMOND-CBM:dbCAN_4:DIAMOND -7.363322e-03 -0.023142852
## GT:dbCAN_4:DIAMOND-CBM:dbCAN_4:DIAMOND -4.468651e-03 -0.020248181
## PL:dbCAN_4:DIAMOND-CBM:dbCAN_4:DIAMOND 5.100415e-03 -0.013240964
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND -3.346563e-03 -0.021567195
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND -1.134806e-03 -0.016914336
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 1.379361e-03 -0.014606447
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND -1.400620e-03 -0.017180150
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND -3.835727e-03 -0.019615257
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 5.563842e-03 -0.012777538
## AA:CUPP-CBM:dbCAN_4:DIAMOND -1.882171e-03 -0.020102803
## CBM:CUPP-CBM:dbCAN_4:DIAMOND 6.195584e-03 -0.009583947
## CE:CUPP-CBM:dbCAN_4:DIAMOND 1.650259e-03 -0.014335549
## GH:CUPP-CBM:dbCAN_4:DIAMOND -5.215154e-04 -0.016301046
## GT:CUPP-CBM:dbCAN_4:DIAMOND -1.712522e-03 -0.017492053
## PL:CUPP-CBM:dbCAN_4:DIAMOND 5.798165e-03 -0.012543214
## GH:dbCAN_4:DIAMOND-CE:dbCAN_4:DIAMOND -6.641655e-03 -0.022627462
## GT:dbCAN_4:DIAMOND-CE:dbCAN_4:DIAMOND -3.746983e-03 -0.019732790
## PL:dbCAN_4:DIAMOND-CE:dbCAN_4:DIAMOND 5.822083e-03 -0.012697061
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND -2.624895e-03 -0.021024458
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND -4.131382e-04 -0.016398946
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 2.101028e-03 -0.014088428
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND -6.789526e-04 -0.016664760
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND -3.114059e-03 -0.019099867
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 6.285509e-03 -0.012233635
## AA:CUPP-CE:dbCAN_4:DIAMOND -1.160503e-03 -0.019560066
## CBM:CUPP-CE:dbCAN_4:DIAMOND 6.917251e-03 -0.009068556
## CE:CUPP-CE:dbCAN_4:DIAMOND 2.371926e-03 -0.013817530
## GH:CUPP-CE:dbCAN_4:DIAMOND 2.001521e-04 -0.015785655
## GT:CUPP-CE:dbCAN_4:DIAMOND -9.908549e-04 -0.016976662
## PL:CUPP-CE:dbCAN_4:DIAMOND 6.519833e-03 -0.011999311
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND 2.894672e-03 -0.012884859
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND 1.246374e-02 -0.005877642
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 4.016759e-03 -0.014203873
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 6.228517e-03 -0.009551014
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 8.742683e-03 -0.007243124
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 5.962702e-03 -0.009816828
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 3.527595e-03 -0.012251935
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 1.292716e-02 -0.005414216
## AA:CUPP-GH:dbCAN_4:DIAMOND 5.481152e-03 -0.012739481
## CBM:CUPP-GH:dbCAN_4:DIAMOND 1.355891e-02 -0.002220624
## CE:CUPP-GH:dbCAN_4:DIAMOND 9.013581e-03 -0.006972227
## GH:CUPP-GH:dbCAN_4:DIAMOND 6.841807e-03 -0.008937723
## GT:CUPP-GH:dbCAN_4:DIAMOND 5.650800e-03 -0.010128730
## PL:CUPP-GH:dbCAN_4:DIAMOND 1.316149e-02 -0.005179892
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4:DIAMOND 9.569066e-03 -0.008772314
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 1.122088e-03 -0.017098544
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 3.333845e-03 -0.012445685
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 5.848011e-03 -0.010137796
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 3.068030e-03 -0.012711500
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 6.329237e-04 -0.015146607
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 1.003249e-02 -0.008308888
## AA:CUPP-GT:dbCAN_4:DIAMOND 2.586480e-03 -0.015634152
## CBM:CUPP-GT:dbCAN_4:DIAMOND 1.066423e-02 -0.005115296
## CE:CUPP-GT:dbCAN_4:DIAMOND 6.118909e-03 -0.009866898
## GH:CUPP-GT:dbCAN_4:DIAMOND 3.947135e-03 -0.011832395
## GT:CUPP-GT:dbCAN_4:DIAMOND 2.756128e-03 -0.013023402
## PL:CUPP-GT:dbCAN_4:DIAMOND 1.026682e-02 -0.008074564
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -8.446978e-03 -0.028926335
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -6.235221e-03 -0.024576601
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -3.721055e-03 -0.022240198
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -6.501036e-03 -0.024842415
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -8.936142e-03 -0.027277522
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 4.634260e-04 -0.020123435
## AA:CUPP-PL:dbCAN_4:DIAMOND -6.982586e-03 -0.027461943
## CBM:CUPP-PL:dbCAN_4:DIAMOND 1.095168e-03 -0.017246212
## CE:CUPP-PL:dbCAN_4:DIAMOND -3.450157e-03 -0.021969300
## GH:CUPP-PL:dbCAN_4:DIAMOND -5.621931e-03 -0.023963311
## GT:CUPP-PL:dbCAN_4:DIAMOND -6.812938e-03 -0.025154318
## PL:CUPP-PL:dbCAN_4:DIAMOND 6.977498e-04 -0.019889111
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub 2.211757e-03 -0.016008875
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub 4.725923e-03 -0.013673639
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub 1.945943e-03 -0.016274689
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub -4.891640e-04 -0.018709796
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub 8.910404e-03 -0.011568953
## AA:CUPP-AA:dbCAN_4:dbCAN-sub 1.464392e-03 -0.018906894
## CBM:CUPP-AA:dbCAN_4:dbCAN-sub 9.542146e-03 -0.008678486
## CE:CUPP-AA:dbCAN_4:dbCAN-sub 4.996821e-03 -0.013402741
## GH:CUPP-AA:dbCAN_4:dbCAN-sub 2.825047e-03 -0.015395585
## GT:CUPP-AA:dbCAN_4:dbCAN-sub 1.634040e-03 -0.016586592
## PL:CUPP-AA:dbCAN_4:dbCAN-sub 9.144728e-03 -0.011334629
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:dbCAN-sub 2.514166e-03 -0.013471641
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:dbCAN-sub -2.658144e-04 -0.016045345
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:dbCAN-sub -2.700921e-03 -0.018480451
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:dbCAN-sub 6.698647e-03 -0.011642733
## AA:CUPP-CBM:dbCAN_4:dbCAN-sub -7.473650e-04 -0.018967997
## CBM:CUPP-CBM:dbCAN_4:dbCAN-sub 7.330389e-03 -0.008449141
## CE:CUPP-CBM:dbCAN_4:dbCAN-sub 2.785064e-03 -0.013200743
## GH:CUPP-CBM:dbCAN_4:dbCAN-sub 6.132903e-04 -0.015166240
## GT:CUPP-CBM:dbCAN_4:dbCAN-sub -5.777167e-04 -0.016357247
## PL:CUPP-CBM:dbCAN_4:dbCAN-sub 6.932971e-03 -0.011408409
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4:dbCAN-sub -2.779981e-03 -0.018765788
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4:dbCAN-sub -5.215088e-03 -0.021200895
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4:dbCAN-sub 4.184481e-03 -0.014334663
## AA:CUPP-CE:dbCAN_4:dbCAN-sub -3.261531e-03 -0.021661094
## CBM:CUPP-CE:dbCAN_4:dbCAN-sub 4.816223e-03 -0.011169584
## CE:CUPP-CE:dbCAN_4:dbCAN-sub 2.708978e-04 -0.015918559
## GH:CUPP-CE:dbCAN_4:dbCAN-sub -1.900876e-03 -0.017886683
## GT:CUPP-CE:dbCAN_4:dbCAN-sub -3.091883e-03 -0.019077690
## PL:CUPP-CE:dbCAN_4:dbCAN-sub 4.418805e-03 -0.014100339
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub -2.435107e-03 -0.018214637
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub 6.964462e-03 -0.011376918
## AA:CUPP-GH:dbCAN_4:dbCAN-sub -4.815506e-04 -0.018702183
## CBM:CUPP-GH:dbCAN_4:dbCAN-sub 7.596204e-03 -0.008183327
## CE:CUPP-GH:dbCAN_4:dbCAN-sub 3.050879e-03 -0.012934929
## GH:CUPP-GH:dbCAN_4:dbCAN-sub 8.791047e-04 -0.014900426
## GT:CUPP-GH:dbCAN_4:dbCAN-sub -3.119023e-04 -0.016091433
## PL:CUPP-GH:dbCAN_4:dbCAN-sub 7.198785e-03 -0.011142594
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:dbCAN-sub 9.399568e-03 -0.008941811
## AA:CUPP-GT:dbCAN_4:dbCAN-sub 1.953556e-03 -0.016267076
## CBM:CUPP-GT:dbCAN_4:dbCAN-sub 1.003131e-02 -0.005748220
## CE:CUPP-GT:dbCAN_4:dbCAN-sub 5.485985e-03 -0.010499822
## GH:CUPP-GT:dbCAN_4:dbCAN-sub 3.314211e-03 -0.012465319
## GT:CUPP-GT:dbCAN_4:dbCAN-sub 2.123204e-03 -0.013656326
## PL:CUPP-GT:dbCAN_4:dbCAN-sub 9.633892e-03 -0.008707488
## AA:CUPP-PL:dbCAN_4:dbCAN-sub -7.446012e-03 -0.027925369
## CBM:CUPP-PL:dbCAN_4:dbCAN-sub 6.317421e-04 -0.017709638
## CE:CUPP-PL:dbCAN_4:dbCAN-sub -3.913583e-03 -0.022432726
## GH:CUPP-PL:dbCAN_4:dbCAN-sub -6.085357e-03 -0.024426737
## GT:CUPP-PL:dbCAN_4:dbCAN-sub -7.276364e-03 -0.025617744
## PL:CUPP-PL:dbCAN_4:dbCAN-sub 2.343238e-04 -0.020352537
## CBM:CUPP-AA:CUPP 8.077754e-03 -0.010142878
## CE:CUPP-AA:CUPP 3.532429e-03 -0.014867133
## GH:CUPP-AA:CUPP 1.360655e-03 -0.016859977
## GT:CUPP-AA:CUPP 1.696484e-04 -0.018050984
## PL:CUPP-AA:CUPP 7.680336e-03 -0.012799021
## CE:CUPP-CBM:CUPP -4.545325e-03 -0.020531132
## GH:CUPP-CBM:CUPP -6.717099e-03 -0.022496629
## GT:CUPP-CBM:CUPP -7.908106e-03 -0.023687636
## PL:CUPP-CBM:CUPP -3.974183e-04 -0.018738798
## GH:CUPP-CE:CUPP -2.171774e-03 -0.018157581
## GT:CUPP-CE:CUPP -3.362781e-03 -0.019348588
## PL:CUPP-CE:CUPP 4.147907e-03 -0.014371237
## GT:CUPP-GH:CUPP -1.191007e-03 -0.016970537
## PL:CUPP-GH:CUPP 6.319681e-03 -0.012021699
## PL:CUPP-GT:CUPP 7.510688e-03 -0.010830692
## upr p adj
## CBM:dbCAN_4-AA:dbCAN_4 0.022668769 1.0000000
## CE:dbCAN_4-AA:dbCAN_4 0.023042747 1.0000000
## GH:dbCAN_4-AA:dbCAN_4 0.020213785 1.0000000
## GT:dbCAN_4-AA:dbCAN_4 0.017508981 1.0000000
## PL:dbCAN_4-AA:dbCAN_4 0.029174861 0.9993762
## AA:dbCAN_4:HMMER-AA:dbCAN_4 0.020357012 1.0000000
## CBM:dbCAN_4:HMMER-AA:dbCAN_4 0.023361981 0.9999999
## CE:dbCAN_4:HMMER-AA:dbCAN_4 0.023037036 1.0000000
## GH:dbCAN_4:HMMER-AA:dbCAN_4 0.021411930 1.0000000
## GT:dbCAN_4:HMMER-AA:dbCAN_4 0.017944829 1.0000000
## PL:dbCAN_4:HMMER-AA:dbCAN_4 0.029169308 0.9993833
## AA:dbCAN_4:DIAMOND-AA:dbCAN_4 0.019959920 1.0000000
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4 0.021355758 1.0000000
## CE:dbCAN_4:DIAMOND-AA:dbCAN_4 0.020813020 1.0000000
## GH:dbCAN_4:DIAMOND-AA:dbCAN_4 0.013992435 1.0000000
## GT:dbCAN_4:DIAMOND-AA:dbCAN_4 0.016887107 1.0000000
## PL:dbCAN_4:DIAMOND-AA:dbCAN_4 0.028714898 0.9997696
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4 0.020159849 1.0000000
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4 0.020220952 1.0000000
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4 0.022914049 1.0000000
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4 0.019955138 1.0000000
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4 0.017520031 1.0000000
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4 0.029178324 0.9993718
## AA:CUPP-AA:dbCAN_4 0.021624241 1.0000000
## CBM:CUPP-AA:dbCAN_4 0.027551341 0.9875406
## CE:CUPP-AA:dbCAN_4 0.023184946 1.0000000
## GH:CUPP-AA:dbCAN_4 0.020834242 1.0000000
## GT:CUPP-AA:dbCAN_4 0.019643235 1.0000000
## PL:CUPP-AA:dbCAN_4 0.029412648 0.9989976
## CE:dbCAN_4-CBM:dbCAN_4 0.016180855 1.0000000
## GH:dbCAN_4-CBM:dbCAN_4 0.013324546 1.0000000
## GT:dbCAN_4-CBM:dbCAN_4 0.010619742 0.9999966
## PL:dbCAN_4-CBM:dbCAN_4 0.022588746 1.0000000
## AA:dbCAN_4:HMMER-CBM:dbCAN_4 0.013758221 1.0000000
## CBM:dbCAN_4:HMMER-CBM:dbCAN_4 0.016472742 1.0000000
## CE:dbCAN_4:HMMER-CBM:dbCAN_4 0.016175144 1.0000000
## GH:dbCAN_4:HMMER-CBM:dbCAN_4 0.014522691 1.0000000
## GT:dbCAN_4:HMMER-CBM:dbCAN_4 0.011055590 0.9999995
## PL:dbCAN_4:HMMER-CBM:dbCAN_4 0.022583194 1.0000000
## AA:dbCAN_4:DIAMOND-CBM:dbCAN_4 0.013361130 1.0000000
## CBM:dbCAN_4:DIAMOND-CBM:dbCAN_4 0.014466519 1.0000000
## CE:dbCAN_4:DIAMOND-CBM:dbCAN_4 0.013951128 1.0000000
## GH:dbCAN_4:DIAMOND-CBM:dbCAN_4 0.007103197 0.9681456
## GT:dbCAN_4:DIAMOND-CBM:dbCAN_4 0.009997868 0.9999627
## PL:dbCAN_4:DIAMOND-CBM:dbCAN_4 0.022128784 1.0000000
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 0.013561058 1.0000000
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 0.013331713 1.0000000
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 0.016052157 1.0000000
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 0.013065899 1.0000000
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 0.010630792 0.9999968
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 0.022592210 1.0000000
## AA:CUPP-CBM:dbCAN_4 0.015025450 1.0000000
## CBM:CUPP-CBM:dbCAN_4 0.020662102 0.9999990
## CE:CUPP-CBM:dbCAN_4 0.016323054 1.0000000
## GH:CUPP-CBM:dbCAN_4 0.013945003 1.0000000
## GT:CUPP-CBM:dbCAN_4 0.012753996 1.0000000
## PL:CUPP-CBM:dbCAN_4 0.022826534 1.0000000
## GH:dbCAN_4-CE:dbCAN_4 0.013335775 1.0000000
## GT:dbCAN_4-CE:dbCAN_4 0.010630971 0.9999943
## PL:dbCAN_4-CE:dbCAN_4 0.022571462 1.0000000
## AA:dbCAN_4:HMMER-CE:dbCAN_4 0.013742104 1.0000000
## CBM:dbCAN_4:HMMER-CE:dbCAN_4 0.016483971 1.0000000
## CE:dbCAN_4:HMMER-CE:dbCAN_4 0.016183745 1.0000000
## GH:dbCAN_4:HMMER-CE:dbCAN_4 0.014533920 1.0000000
## GT:dbCAN_4:HMMER-CE:dbCAN_4 0.011066819 0.9999991
## PL:dbCAN_4:HMMER-CE:dbCAN_4 0.022565909 1.0000000
## AA:dbCAN_4:DIAMOND-CE:dbCAN_4 0.013345012 0.9999999
## CBM:dbCAN_4:DIAMOND-CE:dbCAN_4 0.014477748 1.0000000
## CE:dbCAN_4:DIAMOND-CE:dbCAN_4 0.013959730 1.0000000
## GH:dbCAN_4:DIAMOND-CE:dbCAN_4 0.007114426 0.9643207
## GT:dbCAN_4:DIAMOND-CE:dbCAN_4 0.010009097 0.9999440
## PL:dbCAN_4:DIAMOND-CE:dbCAN_4 0.022111500 1.0000000
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4 0.013544940 1.0000000
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4 0.013342942 1.0000000
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4 0.016060758 1.0000000
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4 0.013077128 1.0000000
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4 0.010642021 0.9999946
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4 0.022574926 1.0000000
## AA:CUPP-CE:dbCAN_4 0.015009332 1.0000000
## CBM:CUPP-CE:dbCAN_4 0.020673332 0.9999997
## CE:CUPP-CE:dbCAN_4 0.016331656 1.0000000
## GH:CUPP-CE:dbCAN_4 0.013956233 1.0000000
## GT:CUPP-CE:dbCAN_4 0.012765226 1.0000000
## PL:CUPP-CE:dbCAN_4 0.022809249 1.0000000
## GT:dbCAN_4-GH:dbCAN_4 0.013074726 1.0000000
## PL:dbCAN_4-GH:dbCAN_4 0.025043730 0.9999647
## AA:dbCAN_4:HMMER-GH:dbCAN_4 0.016213205 1.0000000
## CBM:dbCAN_4:HMMER-GH:dbCAN_4 0.018927726 1.0000000
## CE:dbCAN_4:HMMER-GH:dbCAN_4 0.018630128 1.0000000
## GH:dbCAN_4:HMMER-GH:dbCAN_4 0.016977675 1.0000000
## GT:dbCAN_4:HMMER-GH:dbCAN_4 0.013510574 1.0000000
## PL:dbCAN_4:HMMER-GH:dbCAN_4 0.025038178 0.9999653
## AA:dbCAN_4:DIAMOND-GH:dbCAN_4 0.015816113 1.0000000
## CBM:dbCAN_4:DIAMOND-GH:dbCAN_4 0.016921503 1.0000000
## CE:dbCAN_4:DIAMOND-GH:dbCAN_4 0.016406112 1.0000000
## GH:dbCAN_4:DIAMOND-GH:dbCAN_4 0.009558181 0.9998416
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4 0.012452852 1.0000000
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4 0.024583768 0.9999920
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4 0.016016042 1.0000000
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4 0.015786697 1.0000000
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4 0.018507141 1.0000000
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4 0.015520883 1.0000000
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4 0.013085776 1.0000000
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4 0.025047194 0.9999643
## AA:CUPP-GH:dbCAN_4 0.017480434 1.0000000
## CBM:CUPP-GH:dbCAN_4 0.023117086 0.9970833
## CE:CUPP-GH:dbCAN_4 0.018778038 1.0000000
## GH:CUPP-GH:dbCAN_4 0.016399987 1.0000000
## GT:CUPP-GH:dbCAN_4 0.015208980 1.0000000
## PL:CUPP-GH:dbCAN_4 0.025281518 0.9999289
## PL:dbCAN_4-GT:dbCAN_4 0.027748534 0.9872667
## AA:dbCAN_4:HMMER-GT:dbCAN_4 0.018918009 1.0000000
## CBM:dbCAN_4:HMMER-GT:dbCAN_4 0.021632530 0.9999522
## CE:dbCAN_4:HMMER-GT:dbCAN_4 0.021334932 0.9999944
## GH:dbCAN_4:HMMER-GT:dbCAN_4 0.019682479 1.0000000
## GT:dbCAN_4:HMMER-GT:dbCAN_4 0.016215378 1.0000000
## PL:dbCAN_4:HMMER-GT:dbCAN_4 0.027742982 0.9873714
## AA:dbCAN_4:DIAMOND-GT:dbCAN_4 0.018520918 1.0000000
## CBM:dbCAN_4:DIAMOND-GT:dbCAN_4 0.019626307 1.0000000
## CE:dbCAN_4:DIAMOND-GT:dbCAN_4 0.019110917 1.0000000
## GH:dbCAN_4:DIAMOND-GT:dbCAN_4 0.012262985 1.0000000
## GT:dbCAN_4:DIAMOND-GT:dbCAN_4 0.015157656 1.0000000
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4 0.027288572 0.9938517
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4 0.018720846 1.0000000
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4 0.018491501 1.0000000
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4 0.021211945 0.9999966
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4 0.018225687 1.0000000
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4 0.015790580 1.0000000
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4 0.027751998 0.9872011
## AA:CUPP-GT:dbCAN_4 0.020185238 1.0000000
## CBM:CUPP-GT:dbCAN_4 0.025821890 0.8493728
## CE:CUPP-GT:dbCAN_4 0.021482842 0.9999900
## GH:CUPP-GT:dbCAN_4 0.019104791 1.0000000
## GT:CUPP-GT:dbCAN_4 0.017913785 1.0000000
## PL:CUPP-GT:dbCAN_4 0.027986322 0.9820793
## AA:dbCAN_4:HMMER-PL:dbCAN_4 0.011769580 0.9993577
## CBM:dbCAN_4:HMMER-PL:dbCAN_4 0.014787225 1.0000000
## CE:dbCAN_4:HMMER-PL:dbCAN_4 0.014461113 1.0000000
## GH:dbCAN_4:HMMER-PL:dbCAN_4 0.012837174 0.9999995
## GT:dbCAN_4:HMMER-PL:dbCAN_4 0.009370073 0.9935978
## PL:dbCAN_4:HMMER-PL:dbCAN_4 0.020581309 1.0000000
## AA:dbCAN_4:DIAMOND-PL:dbCAN_4 0.011372488 0.9986057
## CBM:dbCAN_4:DIAMOND-PL:dbCAN_4 0.012781002 0.9999994
## CE:dbCAN_4:DIAMOND-PL:dbCAN_4 0.012237098 0.9999925
## GH:dbCAN_4:DIAMOND-PL:dbCAN_4 0.005417680 0.6727076
## GT:dbCAN_4:DIAMOND-PL:dbCAN_4 0.008312351 0.9702751
## PL:dbCAN_4:DIAMOND-PL:dbCAN_4 0.020126899 1.0000000
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4 0.011572417 0.9990477
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4 0.011646196 0.9999655
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4 0.014338126 1.0000000
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4 0.011380382 0.9999245
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4 0.008945275 0.9874743
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4 0.020590325 1.0000000
## AA:CUPP-PL:dbCAN_4 0.013036809 0.9999684
## CBM:CUPP-PL:dbCAN_4 0.018976585 1.0000000
## CE:CUPP-PL:dbCAN_4 0.014609024 1.0000000
## GH:CUPP-PL:dbCAN_4 0.012259487 0.9999954
## GT:CUPP-PL:dbCAN_4 0.011068480 0.9998234
## PL:CUPP-PL:dbCAN_4 0.020824649 1.0000000
## CBM:dbCAN_4:HMMER-AA:dbCAN_4:HMMER 0.023376254 0.9999999
## CE:dbCAN_4:HMMER-AA:dbCAN_4:HMMER 0.023051310 1.0000000
## GH:dbCAN_4:HMMER-AA:dbCAN_4:HMMER 0.021426204 1.0000000
## GT:dbCAN_4:HMMER-AA:dbCAN_4:HMMER 0.017959103 1.0000000
## PL:dbCAN_4:HMMER-AA:dbCAN_4:HMMER 0.029183582 0.9993650
## AA:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 0.019974194 1.0000000
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 0.021370031 1.0000000
## CE:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 0.020827294 1.0000000
## GH:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 0.014006709 1.0000000
## GT:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 0.016901381 1.0000000
## PL:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 0.028729172 0.9997620
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 0.020174122 1.0000000
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 0.020235226 1.0000000
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 0.022928322 1.0000000
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 0.019969411 1.0000000
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 0.017534305 1.0000000
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 0.029192598 0.9993532
## AA:CUPP-AA:dbCAN_4:HMMER 0.021638515 1.0000000
## CBM:CUPP-AA:dbCAN_4:HMMER 0.027565615 0.9872713
## CE:CUPP-AA:dbCAN_4:HMMER 0.023199220 1.0000000
## GH:CUPP-AA:dbCAN_4:HMMER 0.020848516 1.0000000
## GT:CUPP-AA:dbCAN_4:HMMER 0.019657509 1.0000000
## PL:CUPP-AA:dbCAN_4:HMMER 0.029426922 0.9989695
## CE:dbCAN_4:HMMER-CBM:dbCAN_4:HMMER 0.015481932 1.0000000
## GH:dbCAN_4:HMMER-CBM:dbCAN_4:HMMER 0.013829480 1.0000000
## GT:dbCAN_4:HMMER-CBM:dbCAN_4:HMMER 0.010362378 0.9999904
## PL:dbCAN_4:HMMER-CBM:dbCAN_4:HMMER 0.021889982 1.0000000
## AA:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 0.012667918 0.9999993
## CBM:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 0.013773307 1.0000000
## CE:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 0.013257917 1.0000000
## GH:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 0.006409985 0.9231154
## GT:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 0.009304657 0.9996645
## PL:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 0.021435572 1.0000000
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 0.012867846 0.9999997
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 0.012638502 1.0000000
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 0.015358945 1.0000000
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 0.012372687 1.0000000
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 0.009937580 0.9999540
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 0.021898998 1.0000000
## AA:CUPP-CBM:dbCAN_4:HMMER 0.014332238 1.0000000
## CBM:CUPP-CBM:dbCAN_4:HMMER 0.019968891 1.0000000
## CE:CUPP-CBM:dbCAN_4:HMMER 0.015629843 1.0000000
## GH:CUPP-CBM:dbCAN_4:HMMER 0.013251792 1.0000000
## GT:CUPP-CBM:dbCAN_4:HMMER 0.012060785 1.0000000
## PL:CUPP-CBM:dbCAN_4:HMMER 0.022133322 1.0000000
## GH:dbCAN_4:HMMER-CE:dbCAN_4:HMMER 0.014539632 1.0000000
## GT:dbCAN_4:HMMER-CE:dbCAN_4:HMMER 0.011072531 0.9999992
## PL:dbCAN_4:HMMER-CE:dbCAN_4:HMMER 0.022571621 1.0000000
## AA:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 0.013350723 0.9999999
## CBM:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 0.014483459 1.0000000
## CE:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 0.013965441 1.0000000
## GH:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 0.007120137 0.9645991
## GT:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 0.010014809 0.9999451
## PL:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 0.022117211 1.0000000
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 0.013550652 1.0000000
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 0.013348654 1.0000000
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 0.016066469 1.0000000
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 0.013082839 1.0000000
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 0.010647733 0.9999947
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 0.022580637 1.0000000
## AA:CUPP-CE:dbCAN_4:HMMER 0.015015044 1.0000000
## CBM:CUPP-CE:dbCAN_4:HMMER 0.020679043 0.9999997
## CE:CUPP-CE:dbCAN_4:HMMER 0.016337367 1.0000000
## GH:CUPP-CE:dbCAN_4:HMMER 0.013961944 1.0000000
## GT:CUPP-CE:dbCAN_4:HMMER 0.012770937 1.0000000
## PL:CUPP-CE:dbCAN_4:HMMER 0.022814961 1.0000000
## GT:dbCAN_4:HMMER-GH:dbCAN_4:HMMER 0.012312429 1.0000000
## PL:dbCAN_4:HMMER-GH:dbCAN_4:HMMER 0.023840033 0.9999995
## AA:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 0.014617969 1.0000000
## CBM:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 0.015723358 1.0000000
## CE:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 0.015207968 1.0000000
## GH:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 0.008360036 0.9965179
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 0.011254708 0.9999998
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 0.023385623 0.9999999
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 0.014817897 1.0000000
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 0.014588552 1.0000000
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 0.017308996 1.0000000
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 0.014322738 1.0000000
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 0.011887631 1.0000000
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 0.023849049 0.9999995
## AA:CUPP-GH:dbCAN_4:HMMER 0.016282289 1.0000000
## CBM:CUPP-GH:dbCAN_4:HMMER 0.021918942 0.9998773
## CE:CUPP-GH:dbCAN_4:HMMER 0.017579894 1.0000000
## GH:CUPP-GH:dbCAN_4:HMMER 0.015201843 1.0000000
## GT:CUPP-GH:dbCAN_4:HMMER 0.014010836 1.0000000
## PL:CUPP-GH:dbCAN_4:HMMER 0.024083373 0.9999987
## PL:dbCAN_4:HMMER-GT:dbCAN_4:HMMER 0.027307134 0.9936570
## AA:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 0.018085070 1.0000000
## CBM:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 0.019190459 1.0000000
## CE:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 0.018675069 1.0000000
## GH:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 0.011827137 1.0000000
## GT:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 0.014721809 1.0000000
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 0.026852724 0.9971781
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 0.018284998 1.0000000
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 0.018055653 1.0000000
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 0.020776097 0.9999995
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 0.017789839 1.0000000
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 0.015354732 1.0000000
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 0.027316150 0.9935606
## AA:CUPP-GT:dbCAN_4:HMMER 0.019749390 1.0000000
## CBM:CUPP-GT:dbCAN_4:HMMER 0.025386043 0.9007136
## CE:CUPP-GT:dbCAN_4:HMMER 0.021046995 0.9999983
## GH:CUPP-GT:dbCAN_4:HMMER 0.018668944 1.0000000
## GT:CUPP-GT:dbCAN_4:HMMER 0.017477937 1.0000000
## PL:CUPP-GT:dbCAN_4:HMMER 0.027550474 0.9905887
## AA:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 0.011378041 0.9986201
## CBM:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 0.012786554 0.9999994
## CE:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 0.012242651 0.9999927
## GH:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 0.005423232 0.6736087
## GT:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 0.008317904 0.9704803
## PL:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 0.020132451 1.0000000
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 0.011577969 0.9990579
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 0.011651749 0.9999660
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 0.014343679 1.0000000
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 0.011385934 0.9999257
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 0.008950828 0.9875775
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 0.020595877 1.0000000
## AA:CUPP-PL:dbCAN_4:HMMER 0.013042361 0.9999689
## CBM:CUPP-PL:dbCAN_4:HMMER 0.018982138 1.0000000
## CE:CUPP-PL:dbCAN_4:HMMER 0.014614577 1.0000000
## GH:CUPP-PL:dbCAN_4:HMMER 0.012265039 0.9999955
## GT:CUPP-PL:dbCAN_4:HMMER 0.011074032 0.9998259
## PL:CUPP-PL:dbCAN_4:HMMER 0.020830201 1.0000000
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND 0.021767123 1.0000000
## CE:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND 0.021224386 1.0000000
## GH:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND 0.014403801 1.0000000
## GT:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND 0.017298473 1.0000000
## PL:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND 0.029126264 0.9994357
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 0.020571214 1.0000000
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 0.020632317 1.0000000
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 0.023325414 1.0000000
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 0.020366503 1.0000000
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 0.017931396 1.0000000
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 0.029589690 0.9985967
## AA:CUPP-AA:dbCAN_4:DIAMOND 0.022035606 1.0000000
## CBM:CUPP-AA:dbCAN_4:DIAMOND 0.027962707 0.9776752
## CE:CUPP-AA:dbCAN_4:DIAMOND 0.023596312 0.9999999
## GH:CUPP-AA:dbCAN_4:DIAMOND 0.021245608 1.0000000
## GT:CUPP-AA:dbCAN_4:DIAMOND 0.020054601 1.0000000
## PL:CUPP-AA:dbCAN_4:DIAMOND 0.029824014 0.9978553
## CE:dbCAN_4:DIAMOND-CBM:dbCAN_4:DIAMOND 0.015264140 1.0000000
## GH:dbCAN_4:DIAMOND-CBM:dbCAN_4:DIAMOND 0.008416208 0.9969147
## GT:dbCAN_4:DIAMOND-CBM:dbCAN_4:DIAMOND 0.011310880 0.9999999
## PL:dbCAN_4:DIAMOND-CBM:dbCAN_4:DIAMOND 0.023441795 0.9999999
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 0.014874069 1.0000000
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 0.014644725 1.0000000
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 0.017365168 1.0000000
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 0.014378910 1.0000000
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 0.011943803 1.0000000
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 0.023905221 0.9999994
## AA:CUPP-CBM:dbCAN_4:DIAMOND 0.016338461 1.0000000
## CBM:CUPP-CBM:dbCAN_4:DIAMOND 0.021975114 0.9998538
## CE:CUPP-CBM:dbCAN_4:DIAMOND 0.017636066 1.0000000
## GH:CUPP-CBM:dbCAN_4:DIAMOND 0.015258015 1.0000000
## GT:CUPP-CBM:dbCAN_4:DIAMOND 0.014067008 1.0000000
## PL:CUPP-CBM:dbCAN_4:DIAMOND 0.024139545 0.9999984
## GH:dbCAN_4:DIAMOND-CE:dbCAN_4:DIAMOND 0.009344153 0.9995785
## GT:dbCAN_4:DIAMOND-CE:dbCAN_4:DIAMOND 0.012238824 1.0000000
## PL:dbCAN_4:DIAMOND-CE:dbCAN_4:DIAMOND 0.024341226 0.9999986
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 0.015774667 1.0000000
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 0.015572669 1.0000000
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 0.018290485 1.0000000
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 0.015306855 1.0000000
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 0.012871748 1.0000000
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 0.024804652 0.9999924
## AA:CUPP-CE:dbCAN_4:DIAMOND 0.017239059 1.0000000
## CBM:CUPP-CE:dbCAN_4:DIAMOND 0.022903058 0.9991286
## CE:CUPP-CE:dbCAN_4:DIAMOND 0.018561382 1.0000000
## GH:CUPP-CE:dbCAN_4:DIAMOND 0.016185959 1.0000000
## GT:CUPP-CE:dbCAN_4:DIAMOND 0.014994953 1.0000000
## PL:CUPP-CE:dbCAN_4:DIAMOND 0.025038976 0.9999836
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND 0.018674202 1.0000000
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND 0.030805117 0.7445357
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 0.022237391 1.0000000
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 0.022008047 0.9998381
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 0.024728490 0.9702037
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 0.021742232 0.9999308
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 0.019307126 1.0000000
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 0.031268544 0.6721452
## AA:CUPP-GH:dbCAN_4:DIAMOND 0.023701784 0.9999995
## CBM:CUPP-GH:dbCAN_4:DIAMOND 0.029338436 0.2344506
## CE:CUPP-GH:dbCAN_4:DIAMOND 0.024999388 0.9568393
## GH:CUPP-GH:dbCAN_4:DIAMOND 0.022621337 0.9990973
## GT:CUPP-GH:dbCAN_4:DIAMOND 0.021430330 0.9999767
## PL:CUPP-GH:dbCAN_4:DIAMOND 0.031502867 0.6335452
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4:DIAMOND 0.027910446 0.9838913
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 0.019342720 1.0000000
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 0.019113375 1.0000000
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 0.021833819 0.9999639
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 0.018847561 1.0000000
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 0.016412454 1.0000000
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 0.028373872 0.9701465
## AA:CUPP-GT:dbCAN_4:DIAMOND 0.020807112 1.0000000
## CBM:CUPP-GT:dbCAN_4:DIAMOND 0.026443764 0.7546004
## CE:CUPP-GT:dbCAN_4:DIAMOND 0.022104716 0.9999108
## GH:CUPP-GT:dbCAN_4:DIAMOND 0.019726665 1.0000000
## GT:CUPP-GT:dbCAN_4:DIAMOND 0.018535658 1.0000000
## PL:CUPP-GT:dbCAN_4:DIAMOND 0.028608196 0.9604092
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 0.012032379 0.9996309
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 0.012106159 0.9999922
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 0.014798089 1.0000000
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 0.011840344 0.9999811
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 0.009405237 0.9939653
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 0.021050287 1.0000000
## AA:CUPP-PL:dbCAN_4:DIAMOND 0.013496771 0.9999917
## CBM:CUPP-PL:dbCAN_4:DIAMOND 0.019436548 1.0000000
## CE:CUPP-PL:dbCAN_4:DIAMOND 0.015068987 1.0000000
## GH:CUPP-PL:dbCAN_4:DIAMOND 0.012719449 0.9999992
## GT:CUPP-PL:dbCAN_4:DIAMOND 0.011528442 0.9999508
## PL:CUPP-PL:dbCAN_4:DIAMOND 0.021284611 1.0000000
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub 0.020432389 1.0000000
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub 0.023125486 1.0000000
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub 0.020166575 1.0000000
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub 0.017731468 1.0000000
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub 0.029389762 0.9990412
## AA:CUPP-AA:dbCAN_4:dbCAN-sub 0.021835678 1.0000000
## CBM:CUPP-AA:dbCAN_4:dbCAN-sub 0.027762778 0.9830433
## CE:CUPP-AA:dbCAN_4:dbCAN-sub 0.023396384 1.0000000
## GH:CUPP-AA:dbCAN_4:dbCAN-sub 0.021045680 1.0000000
## GT:CUPP-AA:dbCAN_4:dbCAN-sub 0.019854673 1.0000000
## PL:CUPP-AA:dbCAN_4:dbCAN-sub 0.029624085 0.9985043
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:dbCAN-sub 0.018499974 1.0000000
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:dbCAN-sub 0.015513716 1.0000000
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:dbCAN-sub 0.013078609 1.0000000
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:dbCAN-sub 0.025040027 0.9999651
## AA:CUPP-CBM:dbCAN_4:dbCAN-sub 0.017473267 1.0000000
## CBM:CUPP-CBM:dbCAN_4:dbCAN-sub 0.023109920 0.9971288
## CE:CUPP-CBM:dbCAN_4:dbCAN-sub 0.018770872 1.0000000
## GH:CUPP-CBM:dbCAN_4:dbCAN-sub 0.016392821 1.0000000
## GT:CUPP-CBM:dbCAN_4:dbCAN-sub 0.015201814 1.0000000
## PL:CUPP-CBM:dbCAN_4:dbCAN-sub 0.025274351 0.9999303
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4:dbCAN-sub 0.013205827 1.0000000
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4:dbCAN-sub 0.010770720 0.9999968
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4:dbCAN-sub 0.022703624 1.0000000
## AA:CUPP-CE:dbCAN_4:dbCAN-sub 0.015138031 1.0000000
## CBM:CUPP-CE:dbCAN_4:dbCAN-sub 0.020802030 0.9999995
## CE:CUPP-CE:dbCAN_4:dbCAN-sub 0.016460354 1.0000000
## GH:CUPP-CE:dbCAN_4:dbCAN-sub 0.014084931 1.0000000
## GT:CUPP-CE:dbCAN_4:dbCAN-sub 0.012893924 1.0000000
## PL:CUPP-CE:dbCAN_4:dbCAN-sub 0.022937948 1.0000000
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub 0.013344424 1.0000000
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub 0.025305841 0.9999238
## AA:CUPP-GH:dbCAN_4:dbCAN-sub 0.017739081 1.0000000
## CBM:CUPP-GH:dbCAN_4:dbCAN-sub 0.023375734 0.9949735
## CE:CUPP-GH:dbCAN_4:dbCAN-sub 0.019036686 1.0000000
## GH:CUPP-GH:dbCAN_4:dbCAN-sub 0.016658635 1.0000000
## GT:CUPP-GH:dbCAN_4:dbCAN-sub 0.015467628 1.0000000
## PL:CUPP-GH:dbCAN_4:dbCAN-sub 0.025540165 0.9998548
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:dbCAN-sub 0.027740948 0.9874095
## AA:CUPP-GT:dbCAN_4:dbCAN-sub 0.020174188 1.0000000
## CBM:CUPP-GT:dbCAN_4:dbCAN-sub 0.025810841 0.8508359
## CE:CUPP-GT:dbCAN_4:dbCAN-sub 0.021471793 0.9999904
## GH:CUPP-GT:dbCAN_4:dbCAN-sub 0.019093742 1.0000000
## GT:CUPP-GT:dbCAN_4:dbCAN-sub 0.017902735 1.0000000
## PL:CUPP-GT:dbCAN_4:dbCAN-sub 0.027975272 0.9823529
## AA:CUPP-PL:dbCAN_4:dbCAN-sub 0.013033345 0.9999681
## CBM:CUPP-PL:dbCAN_4:dbCAN-sub 0.018973122 1.0000000
## CE:CUPP-PL:dbCAN_4:dbCAN-sub 0.014605560 1.0000000
## GH:CUPP-PL:dbCAN_4:dbCAN-sub 0.012256023 0.9999954
## GT:CUPP-PL:dbCAN_4:dbCAN-sub 0.011065016 0.9998218
## PL:CUPP-PL:dbCAN_4:dbCAN-sub 0.020821185 1.0000000
## CBM:CUPP-AA:CUPP 0.026298386 0.9986762
## CE:CUPP-AA:CUPP 0.021931992 1.0000000
## GH:CUPP-AA:CUPP 0.019581287 1.0000000
## GT:CUPP-AA:CUPP 0.018390280 1.0000000
## PL:CUPP-AA:CUPP 0.028159693 0.9999404
## CE:CUPP-CBM:CUPP 0.011440482 0.9999999
## GH:CUPP-CBM:CUPP 0.009062431 0.9993472
## GT:CUPP-CBM:CUPP 0.007871424 0.9908381
## PL:CUPP-CBM:CUPP 0.017943962 1.0000000
## GH:CUPP-CE:CUPP 0.013814034 1.0000000
## GT:CUPP-CE:CUPP 0.012623027 1.0000000
## PL:CUPP-CE:CUPP 0.022667050 1.0000000
## GT:CUPP-GH:CUPP 0.014588523 1.0000000
## PL:CUPP-GH:CUPP 0.024661060 0.9999896
## PL:CUPP-GT:CUPP 0.025852067 0.99967696.5.2 CAZy class sensitivity
Two-way ANOVA to test for differences between the CAZy classes and prediction tools.
## Df Sum Sq Mean Sq F value Pr(>F)
## CAZy_class 5 40.37 8.075 583.1 <2e-16 ***
## Prediction_tool 4 16.91 4.228 305.3 <2e-16 ***
## CAZy_class:Prediction_tool 20 28.74 1.437 103.8 <2e-16 ***
## Residuals 2025 28.04 0.014
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1Statistically significant difference was detected, so follow up with a Tukey test to determine if there are differences between specific groups.
## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistic_value ~ CAZy_class * Prediction_tool, data = class_subset_sens.df)
##
## $`CAZy_class:Prediction_tool`
## diff lwr
## CBM:dbCAN_4-AA:dbCAN_4 -1.942007e-01 -2.748547e-01
## CE:dbCAN_4-AA:dbCAN_4 -1.543221e-02 -9.687828e-02
## GH:dbCAN_4-AA:dbCAN_4 -4.365456e-02 -1.243086e-01
## GT:dbCAN_4-AA:dbCAN_4 -3.586692e-02 -1.165209e-01
## PL:dbCAN_4-AA:dbCAN_4 -1.975939e-02 -1.104117e-01
## AA:dbCAN_4:HMMER-AA:dbCAN_4 -5.696849e-03 -9.587079e-02
## CBM:dbCAN_4:HMMER-AA:dbCAN_4 -5.196450e-01 -6.002990e-01
## CE:dbCAN_4:HMMER-AA:dbCAN_4 -4.079249e-02 -1.222386e-01
## GH:dbCAN_4:HMMER-AA:dbCAN_4 -7.351185e-02 -1.541659e-01
## GT:dbCAN_4:HMMER-AA:dbCAN_4 -1.279955e-01 -2.086496e-01
## PL:dbCAN_4:HMMER-AA:dbCAN_4 -1.975939e-02 -1.104117e-01
## AA:dbCAN_4:DIAMOND-AA:dbCAN_4 -2.369505e-02 -1.138690e-01
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4 -1.163513e-01 -1.970053e-01
## CE:dbCAN_4:DIAMOND-AA:dbCAN_4 -1.819955e-02 -9.964561e-02
## GH:dbCAN_4:DIAMOND-AA:dbCAN_4 -2.001757e-02 -1.006716e-01
## GT:dbCAN_4:DIAMOND-AA:dbCAN_4 -1.859237e-02 -9.924640e-02
## PL:dbCAN_4:DIAMOND-AA:dbCAN_4 5.063301e-03 -8.558902e-02
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4 -4.498106e-03 -9.467205e-02
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4 -1.743624e-01 -2.550164e-01
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4 -1.822565e-02 -9.967172e-02
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4 -4.642733e-02 -1.270814e-01
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4 -3.987581e-02 -1.205298e-01
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4 -1.850783e-02 -1.091602e-01
## AA:CUPP-AA:dbCAN_4 -8.895520e-02 -1.791291e-01
## CBM:CUPP-AA:dbCAN_4 -9.936851e-01 -1.074339e+00
## CE:CUPP-AA:dbCAN_4 -8.225552e-02 -1.637016e-01
## GH:CUPP-AA:dbCAN_4 -8.568402e-02 -1.663380e-01
## GT:CUPP-AA:dbCAN_4 -1.401198e-01 -2.207738e-01
## PL:CUPP-AA:dbCAN_4 -1.426106e-01 -2.332629e-01
## CE:dbCAN_4-CBM:dbCAN_4 1.787685e-01 1.080070e-01
## GH:dbCAN_4-CBM:dbCAN_4 1.505462e-01 8.069772e-02
## GT:dbCAN_4-CBM:dbCAN_4 1.583338e-01 8.848536e-02
## PL:dbCAN_4-CBM:dbCAN_4 1.744413e-01 9.325280e-02
## AA:dbCAN_4:HMMER-CBM:dbCAN_4 1.885039e-01 1.078498e-01
## CBM:dbCAN_4:HMMER-CBM:dbCAN_4 -3.254443e-01 -3.952927e-01
## CE:dbCAN_4:HMMER-CBM:dbCAN_4 1.534082e-01 8.264670e-02
## GH:dbCAN_4:HMMER-CBM:dbCAN_4 1.206889e-01 5.084043e-02
## GT:dbCAN_4:HMMER-CBM:dbCAN_4 6.620519e-02 -3.643251e-03
## PL:dbCAN_4:HMMER-CBM:dbCAN_4 1.744413e-01 9.325280e-02
## AA:dbCAN_4:DIAMOND-CBM:dbCAN_4 1.705057e-01 8.985163e-02
## CBM:dbCAN_4:DIAMOND-CBM:dbCAN_4 7.784943e-02 8.000995e-03
## CE:dbCAN_4:DIAMOND-CBM:dbCAN_4 1.760012e-01 1.052396e-01
## GH:dbCAN_4:DIAMOND-CBM:dbCAN_4 1.741831e-01 1.043347e-01
## GT:dbCAN_4:DIAMOND-CBM:dbCAN_4 1.756083e-01 1.057599e-01
## PL:dbCAN_4:DIAMOND-CBM:dbCAN_4 1.992640e-01 1.180755e-01
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 1.897026e-01 1.090486e-01
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 1.983829e-02 -5.001015e-02
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 1.759751e-01 1.052135e-01
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 1.477734e-01 7.792494e-02
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 1.543249e-01 8.447646e-02
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 1.756929e-01 9.450436e-02
## AA:CUPP-CBM:dbCAN_4 1.052455e-01 2.459148e-02
## CBM:CUPP-CBM:dbCAN_4 -7.994844e-01 -8.693329e-01
## CE:CUPP-CBM:dbCAN_4 1.119452e-01 4.118367e-02
## GH:CUPP-CBM:dbCAN_4 1.085167e-01 3.866825e-02
## GT:CUPP-CBM:dbCAN_4 5.408093e-02 -1.576751e-02
## PL:CUPP-CBM:dbCAN_4 5.159008e-02 -2.959843e-02
## GH:dbCAN_4-CE:dbCAN_4 -2.822235e-02 -9.898387e-02
## GT:dbCAN_4-CE:dbCAN_4 -2.043471e-02 -9.119623e-02
## PL:dbCAN_4-CE:dbCAN_4 -4.327183e-03 -8.630258e-02
## AA:dbCAN_4:HMMER-CE:dbCAN_4 9.735361e-03 -7.171071e-02
## CBM:dbCAN_4:HMMER-CE:dbCAN_4 -5.042128e-01 -5.749743e-01
## CE:dbCAN_4:HMMER-CE:dbCAN_4 -2.536028e-02 -9.702326e-02
## GH:dbCAN_4:HMMER-CE:dbCAN_4 -5.807964e-02 -1.288412e-01
## GT:dbCAN_4:HMMER-CE:dbCAN_4 -1.125633e-01 -1.833248e-01
## PL:dbCAN_4:HMMER-CE:dbCAN_4 -4.327183e-03 -8.630258e-02
## AA:dbCAN_4:DIAMOND-CE:dbCAN_4 -8.262845e-03 -8.970891e-02
## CBM:dbCAN_4:DIAMOND-CE:dbCAN_4 -1.009191e-01 -1.716806e-01
## CE:dbCAN_4:DIAMOND-CE:dbCAN_4 -2.767335e-03 -7.443032e-02
## GH:dbCAN_4:DIAMOND-CE:dbCAN_4 -4.585356e-03 -7.534688e-02
## GT:dbCAN_4:DIAMOND-CE:dbCAN_4 -3.160160e-03 -7.392169e-02
## PL:dbCAN_4:DIAMOND-CE:dbCAN_4 2.049551e-02 -6.147988e-02
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4 1.093410e-02 -7.051196e-02
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4 -1.589302e-01 -2.296917e-01
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4 -2.793442e-03 -7.445643e-02
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4 -3.099512e-02 -1.017566e-01
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4 -2.444360e-02 -9.520513e-02
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4 -3.075619e-03 -8.505101e-02
## AA:CUPP-CE:dbCAN_4 -7.352299e-02 -1.549691e-01
## CBM:CUPP-CE:dbCAN_4 -9.782529e-01 -1.049014e+00
## CE:CUPP-CE:dbCAN_4 -6.682331e-02 -1.384863e-01
## GH:CUPP-CE:dbCAN_4 -7.025181e-02 -1.410133e-01
## GT:CUPP-CE:dbCAN_4 -1.246876e-01 -1.954491e-01
## PL:CUPP-CE:dbCAN_4 -1.271784e-01 -2.091538e-01
## GT:dbCAN_4-GH:dbCAN_4 7.787642e-03 -6.206079e-02
## PL:dbCAN_4-GH:dbCAN_4 2.389516e-02 -5.729336e-02
## AA:dbCAN_4:HMMER-GH:dbCAN_4 3.795771e-02 -4.269632e-02
## CBM:dbCAN_4:HMMER-GH:dbCAN_4 -4.759905e-01 -5.458389e-01
## CE:dbCAN_4:HMMER-GH:dbCAN_4 2.862072e-03 -6.789945e-02
## GH:dbCAN_4:HMMER-GH:dbCAN_4 -2.985729e-02 -9.970573e-02
## GT:dbCAN_4:HMMER-GH:dbCAN_4 -8.434097e-02 -1.541894e-01
## PL:dbCAN_4:HMMER-GH:dbCAN_4 2.389516e-02 -5.729336e-02
## AA:dbCAN_4:DIAMOND-GH:dbCAN_4 1.995950e-02 -6.069452e-02
## CBM:dbCAN_4:DIAMOND-GH:dbCAN_4 -7.269672e-02 -1.425452e-01
## CE:dbCAN_4:DIAMOND-GH:dbCAN_4 2.545501e-02 -4.530651e-02
## GH:dbCAN_4:DIAMOND-GH:dbCAN_4 2.363699e-02 -4.621144e-02
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4 2.506219e-02 -4.478625e-02
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4 4.871786e-02 -3.247066e-02
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4 3.915645e-02 -4.149757e-02
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4 -1.307079e-01 -2.005563e-01
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4 2.542891e-02 -4.533262e-02
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4 -2.772773e-03 -7.262121e-02
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4 3.778746e-03 -6.606969e-02
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4 2.514673e-02 -5.604179e-02
## AA:CUPP-GH:dbCAN_4 -4.530064e-02 -1.259547e-01
## CBM:CUPP-GH:dbCAN_4 -9.500306e-01 -1.019879e+00
## CE:CUPP-GH:dbCAN_4 -3.860096e-02 -1.093625e-01
## GH:CUPP-GH:dbCAN_4 -4.202946e-02 -1.118779e-01
## GT:CUPP-GH:dbCAN_4 -9.646522e-02 -1.663137e-01
## PL:CUPP-GH:dbCAN_4 -9.895607e-02 -1.801446e-01
## PL:dbCAN_4-GT:dbCAN_4 1.610752e-02 -6.508100e-02
## AA:dbCAN_4:HMMER-GT:dbCAN_4 3.017007e-02 -5.048396e-02
## CBM:dbCAN_4:HMMER-GT:dbCAN_4 -4.837781e-01 -5.536265e-01
## CE:dbCAN_4:HMMER-GT:dbCAN_4 -4.925569e-03 -7.568710e-02
## GH:dbCAN_4:HMMER-GT:dbCAN_4 -3.764493e-02 -1.074934e-01
## GT:dbCAN_4:HMMER-GT:dbCAN_4 -9.212861e-02 -1.619770e-01
## PL:dbCAN_4:HMMER-GT:dbCAN_4 1.610752e-02 -6.508100e-02
## AA:dbCAN_4:DIAMOND-GT:dbCAN_4 1.217186e-02 -6.848217e-02
## CBM:dbCAN_4:DIAMOND-GT:dbCAN_4 -8.048436e-02 -1.503328e-01
## CE:dbCAN_4:DIAMOND-GT:dbCAN_4 1.766737e-02 -5.309416e-02
## GH:dbCAN_4:DIAMOND-GT:dbCAN_4 1.584935e-02 -5.399909e-02
## GT:dbCAN_4:DIAMOND-GT:dbCAN_4 1.727455e-02 -5.257389e-02
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4 4.093022e-02 -4.025830e-02
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4 3.136881e-02 -4.928522e-02
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4 -1.384955e-01 -2.083439e-01
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4 1.764126e-02 -5.312026e-02
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4 -1.056041e-02 -8.040885e-02
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4 -4.008896e-03 -7.385733e-02
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4 1.735909e-02 -6.382943e-02
## AA:CUPP-GT:dbCAN_4 -5.308828e-02 -1.337423e-01
## CBM:CUPP-GT:dbCAN_4 -9.578182e-01 -1.027667e+00
## CE:CUPP-GT:dbCAN_4 -4.638860e-02 -1.171501e-01
## GH:CUPP-GT:dbCAN_4 -4.981711e-02 -1.196655e-01
## GT:CUPP-GT:dbCAN_4 -1.042529e-01 -1.741013e-01
## PL:CUPP-GT:dbCAN_4 -1.067437e-01 -1.879322e-01
## AA:dbCAN_4:HMMER-PL:dbCAN_4 1.406254e-02 -7.658978e-02
## CBM:dbCAN_4:HMMER-PL:dbCAN_4 -4.998856e-01 -5.810741e-01
## CE:dbCAN_4:HMMER-PL:dbCAN_4 -2.103309e-02 -1.030085e-01
## GH:dbCAN_4:HMMER-PL:dbCAN_4 -5.375245e-02 -1.349410e-01
## GT:dbCAN_4:HMMER-PL:dbCAN_4 -1.082361e-01 -1.894247e-01
## PL:dbCAN_4:HMMER-PL:dbCAN_4 -2.997602e-15 -9.112819e-02
## AA:dbCAN_4:DIAMOND-PL:dbCAN_4 -3.935661e-03 -9.458798e-02
## CBM:dbCAN_4:DIAMOND-PL:dbCAN_4 -9.659189e-02 -1.777804e-01
## CE:dbCAN_4:DIAMOND-PL:dbCAN_4 1.559848e-03 -8.041555e-02
## GH:dbCAN_4:DIAMOND-PL:dbCAN_4 -2.581725e-04 -8.144669e-02
## GT:dbCAN_4:DIAMOND-PL:dbCAN_4 1.167023e-03 -8.002150e-02
## PL:dbCAN_4:DIAMOND-PL:dbCAN_4 2.482270e-02 -6.630550e-02
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4 1.526129e-02 -7.539104e-02
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4 -1.546030e-01 -2.357915e-01
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4 1.533742e-03 -8.044165e-02
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4 -2.666794e-02 -1.078565e-01
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4 -2.011642e-02 -1.013049e-01
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4 1.251564e-03 -8.987663e-02
## AA:CUPP-PL:dbCAN_4 -6.919581e-02 -1.598481e-01
## CBM:CUPP-PL:dbCAN_4 -9.739257e-01 -1.055114e+00
## CE:CUPP-PL:dbCAN_4 -6.249612e-02 -1.444715e-01
## GH:CUPP-PL:dbCAN_4 -6.592463e-02 -1.471131e-01
## GT:CUPP-PL:dbCAN_4 -1.203604e-01 -2.015489e-01
## PL:CUPP-PL:dbCAN_4 -1.228512e-01 -2.139794e-01
## CBM:dbCAN_4:HMMER-AA:dbCAN_4:HMMER -5.139482e-01 -5.946022e-01
## CE:dbCAN_4:HMMER-AA:dbCAN_4:HMMER -3.509564e-02 -1.165417e-01
## GH:dbCAN_4:HMMER-AA:dbCAN_4:HMMER -6.781500e-02 -1.484690e-01
## GT:dbCAN_4:HMMER-AA:dbCAN_4:HMMER -1.222987e-01 -2.029527e-01
## PL:dbCAN_4:HMMER-AA:dbCAN_4:HMMER -1.406254e-02 -1.047149e-01
## AA:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER -1.799821e-02 -1.081721e-01
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER -1.106544e-01 -1.913085e-01
## CE:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER -1.250270e-02 -9.394876e-02
## GH:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER -1.432072e-02 -9.497474e-02
## GT:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER -1.289552e-02 -9.354955e-02
## PL:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 1.076015e-02 -7.989217e-02
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 1.198743e-03 -8.897520e-02
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER -1.686656e-01 -2.493196e-01
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER -1.252880e-02 -9.397487e-02
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER -4.073048e-02 -1.213845e-01
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER -3.417896e-02 -1.148330e-01
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER -1.281098e-02 -1.034633e-01
## AA:CUPP-AA:dbCAN_4:HMMER -8.325835e-02 -1.734323e-01
## CBM:CUPP-AA:dbCAN_4:HMMER -9.879883e-01 -1.068642e+00
## CE:CUPP-AA:dbCAN_4:HMMER -7.655867e-02 -1.580047e-01
## GH:CUPP-AA:dbCAN_4:HMMER -7.998717e-02 -1.606412e-01
## GT:CUPP-AA:dbCAN_4:HMMER -1.344229e-01 -2.150770e-01
## PL:CUPP-AA:dbCAN_4:HMMER -1.369138e-01 -2.275661e-01
## CE:dbCAN_4:HMMER-CBM:dbCAN_4:HMMER 4.788525e-01 4.080910e-01
## GH:dbCAN_4:HMMER-CBM:dbCAN_4:HMMER 4.461332e-01 3.762847e-01
## GT:dbCAN_4:HMMER-CBM:dbCAN_4:HMMER 3.916495e-01 3.218011e-01
## PL:dbCAN_4:HMMER-CBM:dbCAN_4:HMMER 4.998856e-01 4.186971e-01
## AA:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 4.959500e-01 4.152959e-01
## CBM:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 4.032937e-01 3.334453e-01
## CE:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 5.014455e-01 4.306839e-01
## GH:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 4.996275e-01 4.297790e-01
## GT:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 5.010526e-01 4.312042e-01
## PL:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 5.247083e-01 4.435198e-01
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 5.151469e-01 4.344929e-01
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 3.452826e-01 2.754342e-01
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 5.014194e-01 4.306578e-01
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 4.732177e-01 4.033693e-01
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 4.797692e-01 4.099208e-01
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 5.011372e-01 4.199487e-01
## AA:CUPP-CBM:dbCAN_4:HMMER 4.306898e-01 3.500358e-01
## CBM:CUPP-CBM:dbCAN_4:HMMER -4.740401e-01 -5.438886e-01
## CE:CUPP-CBM:dbCAN_4:HMMER 4.373895e-01 3.666280e-01
## GH:CUPP-CBM:dbCAN_4:HMMER 4.339610e-01 3.641126e-01
## GT:CUPP-CBM:dbCAN_4:HMMER 3.795252e-01 3.096768e-01
## PL:CUPP-CBM:dbCAN_4:HMMER 3.770344e-01 2.958459e-01
## GH:dbCAN_4:HMMER-CE:dbCAN_4:HMMER -3.271936e-02 -1.034809e-01
## GT:dbCAN_4:HMMER-CE:dbCAN_4:HMMER -8.720304e-02 -1.579646e-01
## PL:dbCAN_4:HMMER-CE:dbCAN_4:HMMER 2.103309e-02 -6.094230e-02
## AA:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 1.709743e-02 -6.434863e-02
## CBM:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER -7.555879e-02 -1.463203e-01
## CE:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 2.259294e-02 -4.907004e-02
## GH:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 2.077492e-02 -4.998661e-02
## GT:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 2.220012e-02 -4.856141e-02
## PL:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 4.585579e-02 -3.611961e-02
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 3.629438e-02 -4.515169e-02
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER -1.335699e-01 -2.043315e-01
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 2.256683e-02 -4.909615e-02
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER -5.634845e-03 -7.639637e-02
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 9.166738e-04 -6.984485e-02
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 2.228466e-02 -5.969074e-02
## AA:CUPP-CE:dbCAN_4:HMMER -4.816271e-02 -1.296088e-01
## CBM:CUPP-CE:dbCAN_4:HMMER -9.528926e-01 -1.023654e+00
## CE:CUPP-CE:dbCAN_4:HMMER -4.146303e-02 -1.131260e-01
## GH:CUPP-CE:dbCAN_4:HMMER -4.489154e-02 -1.156531e-01
## GT:CUPP-CE:dbCAN_4:HMMER -9.932730e-02 -1.700888e-01
## PL:CUPP-CE:dbCAN_4:HMMER -1.018181e-01 -1.837935e-01
## GT:dbCAN_4:HMMER-GH:dbCAN_4:HMMER -5.448368e-02 -1.243321e-01
## PL:dbCAN_4:HMMER-GH:dbCAN_4:HMMER 5.375245e-02 -2.743607e-02
## AA:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 4.981679e-02 -3.083723e-02
## CBM:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER -4.283943e-02 -1.126879e-01
## CE:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 5.531230e-02 -1.544922e-02
## GH:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 5.349428e-02 -1.635415e-02
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 5.491948e-02 -1.492896e-02
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 7.857515e-02 -2.613370e-03
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 6.901374e-02 -1.164029e-02
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER -1.008506e-01 -1.706990e-01
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 5.528620e-02 -1.547533e-02
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 2.708452e-02 -4.276392e-02
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 3.363604e-02 -3.621240e-02
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 5.500402e-02 -2.618450e-02
## AA:CUPP-GH:dbCAN_4:HMMER -1.544335e-02 -9.609738e-02
## CBM:CUPP-GH:dbCAN_4:HMMER -9.201733e-01 -9.900217e-01
## CE:CUPP-GH:dbCAN_4:HMMER -8.743671e-03 -7.950520e-02
## GH:CUPP-GH:dbCAN_4:HMMER -1.217217e-02 -8.202061e-02
## GT:CUPP-GH:dbCAN_4:HMMER -6.660793e-02 -1.364564e-01
## PL:CUPP-GH:dbCAN_4:HMMER -6.909878e-02 -1.502873e-01
## PL:dbCAN_4:HMMER-GT:dbCAN_4:HMMER 1.082361e-01 2.704761e-02
## AA:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 1.043005e-01 2.364644e-02
## CBM:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 1.164425e-02 -5.820419e-02
## CE:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 1.097960e-01 3.903445e-02
## GH:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 1.079780e-01 3.812952e-02
## GT:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 1.094032e-01 3.955472e-02
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 1.330588e-01 5.187031e-02
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 1.234974e-01 4.284339e-02
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER -4.636690e-02 -1.162153e-01
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 1.097699e-01 3.900835e-02
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 8.156819e-02 1.171976e-02
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 8.811971e-02 1.827128e-02
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 1.094877e-01 2.829918e-02
## AA:CUPP-GT:dbCAN_4:HMMER 3.904033e-02 -4.161370e-02
## CBM:CUPP-GT:dbCAN_4:HMMER -8.656896e-01 -9.355380e-01
## CE:CUPP-GT:dbCAN_4:HMMER 4.574001e-02 -2.502152e-02
## GH:CUPP-GT:dbCAN_4:HMMER 4.231150e-02 -2.753693e-02
## GT:CUPP-GT:dbCAN_4:HMMER -1.212426e-02 -8.197269e-02
## PL:CUPP-GT:dbCAN_4:HMMER -1.461510e-02 -9.580362e-02
## AA:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER -3.935661e-03 -9.458798e-02
## CBM:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER -9.659189e-02 -1.777804e-01
## CE:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 1.559848e-03 -8.041555e-02
## GH:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER -2.581725e-04 -8.144669e-02
## GT:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 1.167023e-03 -8.002150e-02
## PL:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 2.482270e-02 -6.630550e-02
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 1.526129e-02 -7.539104e-02
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER -1.546030e-01 -2.357915e-01
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 1.533742e-03 -8.044165e-02
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER -2.666794e-02 -1.078565e-01
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER -2.011642e-02 -1.013049e-01
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 1.251564e-03 -8.987663e-02
## AA:CUPP-PL:dbCAN_4:HMMER -6.919581e-02 -1.598481e-01
## CBM:CUPP-PL:dbCAN_4:HMMER -9.739257e-01 -1.055114e+00
## CE:CUPP-PL:dbCAN_4:HMMER -6.249612e-02 -1.444715e-01
## GH:CUPP-PL:dbCAN_4:HMMER -6.592463e-02 -1.471131e-01
## GT:CUPP-PL:dbCAN_4:HMMER -1.203604e-01 -2.015489e-01
## PL:CUPP-PL:dbCAN_4:HMMER -1.228512e-01 -2.139794e-01
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND -9.265622e-02 -1.733103e-01
## CE:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND 5.495510e-03 -7.595056e-02
## GH:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND 3.677489e-03 -7.697654e-02
## GT:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND 5.102685e-03 -7.555134e-02
## PL:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND 2.875836e-02 -6.189397e-02
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 1.919695e-02 -7.097699e-02
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND -1.506674e-01 -2.313214e-01
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 5.469403e-03 -7.597666e-02
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND -2.273228e-02 -1.033863e-01
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND -1.618076e-02 -9.683478e-02
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 5.187226e-03 -8.546510e-02
## AA:CUPP-AA:dbCAN_4:DIAMOND -6.526014e-02 -1.554341e-01
## CBM:CUPP-AA:dbCAN_4:DIAMOND -9.699901e-01 -1.050644e+00
## CE:CUPP-AA:dbCAN_4:DIAMOND -5.856046e-02 -1.400065e-01
## GH:CUPP-AA:dbCAN_4:DIAMOND -6.198897e-02 -1.426430e-01
## GT:CUPP-AA:dbCAN_4:DIAMOND -1.164247e-01 -1.970788e-01
## PL:CUPP-AA:dbCAN_4:DIAMOND -1.189156e-01 -2.095679e-01
## CE:dbCAN_4:DIAMOND-CBM:dbCAN_4:DIAMOND 9.815173e-02 2.739021e-02
## GH:dbCAN_4:DIAMOND-CBM:dbCAN_4:DIAMOND 9.633371e-02 2.648528e-02
## GT:dbCAN_4:DIAMOND-CBM:dbCAN_4:DIAMOND 9.775891e-02 2.791047e-02
## PL:dbCAN_4:DIAMOND-CBM:dbCAN_4:DIAMOND 1.214146e-01 4.022606e-02
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 1.118532e-01 3.119915e-02
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND -5.801114e-02 -1.278596e-01
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 9.812563e-02 2.736410e-02
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 6.992395e-02 7.551239e-05
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 7.647547e-02 6.627031e-03
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 9.784345e-02 1.665493e-02
## AA:CUPP-CBM:dbCAN_4:DIAMOND 2.739608e-02 -5.325795e-02
## CBM:CUPP-CBM:dbCAN_4:DIAMOND -8.773339e-01 -9.471823e-01
## CE:CUPP-CBM:dbCAN_4:DIAMOND 3.409576e-02 -3.666577e-02
## GH:CUPP-CBM:dbCAN_4:DIAMOND 3.066726e-02 -3.918118e-02
## GT:CUPP-CBM:dbCAN_4:DIAMOND -2.376850e-02 -9.361694e-02
## PL:CUPP-CBM:dbCAN_4:DIAMOND -2.625935e-02 -1.074479e-01
## GH:dbCAN_4:DIAMOND-CE:dbCAN_4:DIAMOND -1.818021e-03 -7.257955e-02
## GT:dbCAN_4:DIAMOND-CE:dbCAN_4:DIAMOND -3.928251e-04 -7.115435e-02
## PL:dbCAN_4:DIAMOND-CE:dbCAN_4:DIAMOND 2.326285e-02 -5.871255e-02
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 1.370144e-02 -6.774463e-02
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND -1.561629e-01 -2.269244e-01
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND -2.610693e-05 -7.168909e-02
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND -2.822779e-02 -9.898931e-02
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND -2.167627e-02 -9.243779e-02
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND -3.082840e-04 -8.228368e-02
## AA:CUPP-CE:dbCAN_4:DIAMOND -7.075565e-02 -1.522017e-01
## CBM:CUPP-CE:dbCAN_4:DIAMOND -9.754856e-01 -1.046247e+00
## CE:CUPP-CE:dbCAN_4:DIAMOND -6.405597e-02 -1.357190e-01
## GH:CUPP-CE:dbCAN_4:DIAMOND -6.748448e-02 -1.382460e-01
## GT:CUPP-CE:dbCAN_4:DIAMOND -1.219202e-01 -1.926818e-01
## PL:CUPP-CE:dbCAN_4:DIAMOND -1.244111e-01 -2.063865e-01
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND 1.425196e-03 -6.842324e-02
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND 2.508087e-02 -5.610765e-02
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 1.551946e-02 -6.513457e-02
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND -1.543449e-01 -2.241933e-01
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 1.791914e-03 -6.896961e-02
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND -2.640976e-02 -9.625820e-02
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND -1.985825e-02 -8.970668e-02
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 1.509737e-03 -7.967878e-02
## AA:CUPP-GH:dbCAN_4:DIAMOND -6.893763e-02 -1.495917e-01
## CBM:CUPP-GH:dbCAN_4:DIAMOND -9.736676e-01 -1.043516e+00
## CE:CUPP-GH:dbCAN_4:DIAMOND -6.223795e-02 -1.329995e-01
## GH:CUPP-GH:dbCAN_4:DIAMOND -6.566646e-02 -1.355149e-01
## GT:CUPP-GH:dbCAN_4:DIAMOND -1.201022e-01 -1.899507e-01
## PL:CUPP-GH:dbCAN_4:DIAMOND -1.225931e-01 -2.037816e-01
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4:DIAMOND 2.365567e-02 -5.753285e-02
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 1.409426e-02 -6.655976e-02
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND -1.557701e-01 -2.256185e-01
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 3.667181e-04 -7.039481e-02
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND -2.783496e-02 -9.768340e-02
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND -2.128344e-02 -9.113188e-02
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 8.454105e-05 -8.110398e-02
## AA:CUPP-GT:dbCAN_4:DIAMOND -7.036283e-02 -1.510169e-01
## CBM:CUPP-GT:dbCAN_4:DIAMOND -9.750928e-01 -1.044941e+00
## CE:CUPP-GT:dbCAN_4:DIAMOND -6.366315e-02 -1.344247e-01
## GH:CUPP-GT:dbCAN_4:DIAMOND -6.709165e-02 -1.369401e-01
## GT:CUPP-GT:dbCAN_4:DIAMOND -1.215274e-01 -1.913758e-01
## PL:CUPP-GT:dbCAN_4:DIAMOND -1.240183e-01 -2.052068e-01
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -9.561407e-03 -1.002137e-01
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -1.794257e-01 -2.606142e-01
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -2.328895e-02 -1.052643e-01
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -5.149063e-02 -1.326792e-01
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -4.493911e-02 -1.261276e-01
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -2.357113e-02 -1.146993e-01
## AA:CUPP-PL:dbCAN_4:DIAMOND -9.401850e-02 -1.846708e-01
## CBM:CUPP-PL:dbCAN_4:DIAMOND -9.987484e-01 -1.079937e+00
## CE:CUPP-PL:dbCAN_4:DIAMOND -8.731882e-02 -1.692942e-01
## GH:CUPP-PL:dbCAN_4:DIAMOND -9.074732e-02 -1.719358e-01
## GT:CUPP-PL:dbCAN_4:DIAMOND -1.451831e-01 -2.263716e-01
## PL:CUPP-PL:dbCAN_4:DIAMOND -1.476739e-01 -2.388021e-01
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub -1.698643e-01 -2.505183e-01
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub -1.372755e-02 -9.517361e-02
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub -4.192923e-02 -1.225833e-01
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub -3.537771e-02 -1.160317e-01
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub -1.400972e-02 -1.046620e-01
## AA:CUPP-AA:dbCAN_4:dbCAN-sub -8.445709e-02 -1.746310e-01
## CBM:CUPP-AA:dbCAN_4:dbCAN-sub -9.891870e-01 -1.069841e+00
## CE:CUPP-AA:dbCAN_4:dbCAN-sub -7.775741e-02 -1.592035e-01
## GH:CUPP-AA:dbCAN_4:dbCAN-sub -8.118592e-02 -1.618399e-01
## GT:CUPP-AA:dbCAN_4:dbCAN-sub -1.356217e-01 -2.162757e-01
## PL:CUPP-AA:dbCAN_4:dbCAN-sub -1.381125e-01 -2.287648e-01
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:dbCAN-sub 1.561368e-01 8.537524e-02
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:dbCAN-sub 1.279351e-01 5.808665e-02
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:dbCAN-sub 1.344866e-01 6.463817e-02
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:dbCAN-sub 1.558546e-01 7.466607e-02
## AA:CUPP-CBM:dbCAN_4:dbCAN-sub 8.540722e-02 4.753195e-03
## CBM:CUPP-CBM:dbCAN_4:dbCAN-sub -8.193227e-01 -8.891711e-01
## CE:CUPP-CBM:dbCAN_4:dbCAN-sub 9.210690e-02 2.134538e-02
## GH:CUPP-CBM:dbCAN_4:dbCAN-sub 8.867840e-02 1.882996e-02
## GT:CUPP-CBM:dbCAN_4:dbCAN-sub 3.424264e-02 -3.560580e-02
## PL:CUPP-CBM:dbCAN_4:dbCAN-sub 3.175180e-02 -4.943672e-02
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4:dbCAN-sub -2.820168e-02 -9.896321e-02
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4:dbCAN-sub -2.165016e-02 -9.241169e-02
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4:dbCAN-sub -2.821771e-04 -8.225757e-02
## AA:CUPP-CE:dbCAN_4:dbCAN-sub -7.072955e-02 -1.521756e-01
## CBM:CUPP-CE:dbCAN_4:dbCAN-sub -9.754595e-01 -1.046221e+00
## CE:CUPP-CE:dbCAN_4:dbCAN-sub -6.402987e-02 -1.356928e-01
## GH:CUPP-CE:dbCAN_4:dbCAN-sub -6.745837e-02 -1.382199e-01
## GT:CUPP-CE:dbCAN_4:dbCAN-sub -1.218941e-01 -1.926557e-01
## PL:CUPP-CE:dbCAN_4:dbCAN-sub -1.243850e-01 -2.063604e-01
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub 6.551519e-03 -6.329692e-02
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub 2.791950e-02 -5.326902e-02
## AA:CUPP-GH:dbCAN_4:dbCAN-sub -4.252787e-02 -1.231819e-01
## CBM:CUPP-GH:dbCAN_4:dbCAN-sub -9.472578e-01 -1.017106e+00
## CE:CUPP-GH:dbCAN_4:dbCAN-sub -3.582819e-02 -1.065897e-01
## GH:CUPP-GH:dbCAN_4:dbCAN-sub -3.925669e-02 -1.091051e-01
## GT:CUPP-GH:dbCAN_4:dbCAN-sub -9.369245e-02 -1.635409e-01
## PL:CUPP-GH:dbCAN_4:dbCAN-sub -9.618330e-02 -1.773718e-01
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:dbCAN-sub 2.136798e-02 -5.982054e-02
## AA:CUPP-GT:dbCAN_4:dbCAN-sub -4.907939e-02 -1.297334e-01
## CBM:CUPP-GT:dbCAN_4:dbCAN-sub -9.538093e-01 -1.023658e+00
## CE:CUPP-GT:dbCAN_4:dbCAN-sub -4.237971e-02 -1.131412e-01
## GH:CUPP-GT:dbCAN_4:dbCAN-sub -4.580821e-02 -1.156566e-01
## GT:CUPP-GT:dbCAN_4:dbCAN-sub -1.002440e-01 -1.700924e-01
## PL:CUPP-GT:dbCAN_4:dbCAN-sub -1.027348e-01 -1.839233e-01
## AA:CUPP-PL:dbCAN_4:dbCAN-sub -7.044737e-02 -1.610997e-01
## CBM:CUPP-PL:dbCAN_4:dbCAN-sub -9.751773e-01 -1.056366e+00
## CE:CUPP-PL:dbCAN_4:dbCAN-sub -6.374769e-02 -1.457231e-01
## GH:CUPP-PL:dbCAN_4:dbCAN-sub -6.717619e-02 -1.483647e-01
## GT:CUPP-PL:dbCAN_4:dbCAN-sub -1.216120e-01 -2.028005e-01
## PL:CUPP-PL:dbCAN_4:dbCAN-sub -1.241028e-01 -2.152310e-01
## CBM:CUPP-AA:CUPP -9.047299e-01 -9.853840e-01
## CE:CUPP-AA:CUPP 6.699681e-03 -7.474638e-02
## GH:CUPP-AA:CUPP 3.271178e-03 -7.738285e-02
## GT:CUPP-AA:CUPP -5.116458e-02 -1.318186e-01
## PL:CUPP-AA:CUPP -5.365543e-02 -1.443077e-01
## CE:CUPP-CBM:CUPP 9.114296e-01 8.406681e-01
## GH:CUPP-CBM:CUPP 9.080011e-01 8.381527e-01
## GT:CUPP-CBM:CUPP 8.535654e-01 7.837169e-01
## PL:CUPP-CBM:CUPP 8.510745e-01 7.698860e-01
## GH:CUPP-CE:CUPP -3.428503e-03 -7.419003e-02
## GT:CUPP-CE:CUPP -5.786426e-02 -1.286258e-01
## PL:CUPP-CE:CUPP -6.035511e-02 -1.423305e-01
## GT:CUPP-GH:CUPP -5.443576e-02 -1.242842e-01
## PL:CUPP-GH:CUPP -5.692660e-02 -1.381151e-01
## PL:CUPP-GT:CUPP -2.490844e-03 -8.367936e-02
## upr p adj
## CBM:dbCAN_4-AA:dbCAN_4 -0.1135466841 0.0000000
## CE:dbCAN_4-AA:dbCAN_4 0.0660138556 1.0000000
## GH:dbCAN_4-AA:dbCAN_4 0.0369994688 0.9738617
## GT:dbCAN_4-AA:dbCAN_4 0.0447871104 0.9986049
## PL:dbCAN_4-AA:dbCAN_4 0.0708929295 1.0000000
## AA:dbCAN_4:HMMER-AA:dbCAN_4 0.0844770941 1.0000000
## CBM:dbCAN_4:HMMER-AA:dbCAN_4 -0.4389909905 0.0000000
## CE:dbCAN_4:HMMER-AA:dbCAN_4 0.0406535800 0.9909198
## GH:dbCAN_4:HMMER-AA:dbCAN_4 0.0071421792 0.1402437
## GT:dbCAN_4:HMMER-AA:dbCAN_4 -0.0473414985 0.0000013
## PL:dbCAN_4:HMMER-AA:dbCAN_4 0.0708929295 1.0000000
## AA:dbCAN_4:DIAMOND-AA:dbCAN_4 0.0664788886 1.0000000
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4 -0.0356972529 0.0000287
## CE:dbCAN_4:DIAMOND-AA:dbCAN_4 0.0632465206 1.0000000
## GH:dbCAN_4:DIAMOND-AA:dbCAN_4 0.0606364607 1.0000000
## GT:dbCAN_4:DIAMOND-AA:dbCAN_4 0.0620616567 1.0000000
## PL:dbCAN_4:DIAMOND-AA:dbCAN_4 0.0957156245 1.0000000
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4 0.0856758375 1.0000000
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4 -0.0937083946 0.0000000
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4 0.0632204137 1.0000000
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4 0.0342266959 0.9452054
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4 0.0407782148 0.9924883
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4 0.0721444940 1.0000000
## AA:CUPP-AA:dbCAN_4 0.0012187437 0.0592357
## CBM:CUPP-AA:dbCAN_4 -0.9130311072 0.0000000
## CE:CUPP-AA:dbCAN_4 -0.0008094526 0.0440244
## GH:CUPP-AA:dbCAN_4 -0.0050299950 0.0217098
## GT:CUPP-AA:dbCAN_4 -0.0594657555 0.0000000
## PL:CUPP-AA:dbCAN_4 -0.0519583032 0.0000018
## CE:dbCAN_4-CBM:dbCAN_4 0.2495300274 0.0000000
## GH:dbCAN_4-CBM:dbCAN_4 0.2203945893 0.0000000
## GT:dbCAN_4-CBM:dbCAN_4 0.2281822309 0.0000000
## PL:dbCAN_4-CBM:dbCAN_4 0.2556298369 0.0000000
## AA:dbCAN_4:HMMER-CBM:dbCAN_4 0.2691578888 0.0000000
## CBM:dbCAN_4:HMMER-CBM:dbCAN_4 -0.2555958700 0.0000000
## CE:dbCAN_4:HMMER-CBM:dbCAN_4 0.2241697517 0.0000000
## GH:dbCAN_4:HMMER-CBM:dbCAN_4 0.1905372997 0.0000000
## GT:dbCAN_4:HMMER-CBM:dbCAN_4 0.1360536220 0.0939362
## PL:dbCAN_4:HMMER-CBM:dbCAN_4 0.2556298369 0.0000000
## AA:dbCAN_4:DIAMOND-CBM:dbCAN_4 0.2511596833 0.0000000
## CBM:dbCAN_4:DIAMOND-CBM:dbCAN_4 0.1476978676 0.0101538
## CE:dbCAN_4:DIAMOND-CBM:dbCAN_4 0.2467626924 0.0000000
## GH:dbCAN_4:DIAMOND-CBM:dbCAN_4 0.2440315812 0.0000000
## GT:dbCAN_4:DIAMOND-CBM:dbCAN_4 0.2454567772 0.0000000
## PL:dbCAN_4:DIAMOND-CBM:dbCAN_4 0.2804525319 0.0000000
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 0.2703566322 0.0000000
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 0.0896867259 0.9999999
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 0.2467365855 0.0000000
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 0.2176218164 0.0000000
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 0.2241733353 0.0000000
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 0.2568814014 0.0000000
## AA:CUPP-CBM:dbCAN_4 0.1858995384 0.0004166
## CBM:CUPP-CBM:dbCAN_4 -0.7296359868 0.0000000
## CE:CUPP-CBM:dbCAN_4 0.1827067192 0.0000014
## GH:CUPP-CBM:dbCAN_4 0.1783651255 0.0000027
## GT:CUPP-CBM:dbCAN_4 0.1239293650 0.4583074
## PL:CUPP-CBM:dbCAN_4 0.1327786042 0.8514206
## GH:dbCAN_4-CE:dbCAN_4 0.0425391787 0.9998028
## GT:dbCAN_4-CE:dbCAN_4 0.0503268202 0.9999998
## PL:dbCAN_4-CE:dbCAN_4 0.0776482109 1.0000000
## AA:dbCAN_4:HMMER-CE:dbCAN_4 0.0911814269 1.0000000
## CBM:dbCAN_4:HMMER-CE:dbCAN_4 -0.4334512806 0.0000000
## CE:dbCAN_4:HMMER-CE:dbCAN_4 0.0463027079 0.9999818
## GH:dbCAN_4:HMMER-CE:dbCAN_4 0.0126818891 0.3261698
## GT:dbCAN_4:HMMER-CE:dbCAN_4 -0.0418017886 0.0000012
## PL:dbCAN_4:HMMER-CE:dbCAN_4 0.0776482109 1.0000000
## AA:dbCAN_4:DIAMOND-CE:dbCAN_4 0.0731832214 1.0000000
## CBM:dbCAN_4:DIAMOND-CE:dbCAN_4 -0.0301575430 0.0000401
## CE:dbCAN_4:DIAMOND-CE:dbCAN_4 0.0688956486 1.0000000
## GH:dbCAN_4:DIAMOND-CE:dbCAN_4 0.0661761706 1.0000000
## GT:dbCAN_4:DIAMOND-CE:dbCAN_4 0.0676013665 1.0000000
## PL:dbCAN_4:DIAMOND-CE:dbCAN_4 0.1024709059 1.0000000
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4 0.0923801702 1.0000000
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4 -0.0881686848 0.0000000
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4 0.0688695417 1.0000000
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4 0.0397664057 0.9989231
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4 0.0463179246 0.9999890
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4 0.0788997753 1.0000000
## AA:CUPP-CE:dbCAN_4 0.0079230764 0.1536120
## CBM:CUPP-CE:dbCAN_4 -0.9074913974 0.0000000
## CE:CUPP-CE:dbCAN_4 0.0048396754 0.1117200
## GH:CUPP-CE:dbCAN_4 0.0005097148 0.0547556
## GT:CUPP-CE:dbCAN_4 -0.0539260456 0.0000000
## PL:CUPP-CE:dbCAN_4 -0.0452030218 0.0000028
## GT:dbCAN_4-GH:dbCAN_4 0.0776360779 1.0000000
## PL:dbCAN_4-GH:dbCAN_4 0.1050836839 0.9999997
## AA:dbCAN_4:HMMER-GH:dbCAN_4 0.1186117358 0.9964676
## CBM:dbCAN_4:HMMER-GH:dbCAN_4 -0.4061420230 0.0000000
## CE:dbCAN_4:HMMER-GH:dbCAN_4 0.0736235988 1.0000000
## GH:dbCAN_4:HMMER-GH:dbCAN_4 0.0399911468 0.9992972
## GT:dbCAN_4:HMMER-GH:dbCAN_4 -0.0144925310 0.0023093
## PL:dbCAN_4:HMMER-GH:dbCAN_4 0.1050836839 0.9999997
## AA:dbCAN_4:DIAMOND-GH:dbCAN_4 0.1006135303 1.0000000
## CBM:dbCAN_4:DIAMOND-GH:dbCAN_4 -0.0028482853 0.0292525
## CE:dbCAN_4:DIAMOND-GH:dbCAN_4 0.0962165394 0.9999744
## GH:dbCAN_4:DIAMOND-GH:dbCAN_4 0.0934854283 0.9999929
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4 0.0949106242 0.9999757
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4 0.1299063790 0.9142136
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4 0.1198104792 0.9942807
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4 -0.0608594271 0.0000000
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4 0.0961904325 0.9999749
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4 0.0670756634 1.0000000
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4 0.0736271823 1.0000000
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4 0.1063352484 0.9999990
## AA:CUPP-GH:dbCAN_4 0.0353533854 0.9587747
## CBM:CUPP-GH:dbCAN_4 -0.8801821397 0.0000000
## CE:CUPP-GH:dbCAN_4 0.0321605662 0.9711423
## GH:CUPP-GH:dbCAN_4 0.0278189725 0.9117413
## GT:CUPP-GH:dbCAN_4 -0.0266167879 0.0000983
## PL:CUPP-GH:dbCAN_4 -0.0177675488 0.0019068
## PL:dbCAN_4-GT:dbCAN_4 0.0972960424 1.0000000
## AA:dbCAN_4:HMMER-GT:dbCAN_4 0.1108240943 0.9999434
## CBM:dbCAN_4:HMMER-GT:dbCAN_4 -0.4139296645 0.0000000
## CE:dbCAN_4:HMMER-GT:dbCAN_4 0.0658359572 1.0000000
## GH:dbCAN_4:HMMER-GT:dbCAN_4 0.0322035052 0.9752506
## GT:dbCAN_4:HMMER-GT:dbCAN_4 -0.0222801725 0.0003212
## PL:dbCAN_4:HMMER-GT:dbCAN_4 0.0972960424 1.0000000
## AA:dbCAN_4:DIAMOND-GT:dbCAN_4 0.0928258888 1.0000000
## CBM:dbCAN_4:DIAMOND-GT:dbCAN_4 -0.0106359269 0.0056731
## CE:dbCAN_4:DIAMOND-GT:dbCAN_4 0.0884288979 1.0000000
## GH:dbCAN_4:DIAMOND-GT:dbCAN_4 0.0856977867 1.0000000
## GT:dbCAN_4:DIAMOND-GT:dbCAN_4 0.0871229826 1.0000000
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4 0.1221187374 0.9900218
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4 0.1120228377 0.9998782
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4 -0.0686470687 0.0000000
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4 0.0884027910 1.0000000
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4 0.0592880218 1.0000000
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4 0.0658395408 1.0000000
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4 0.0985476068 1.0000000
## AA:CUPP-GT:dbCAN_4 0.0275657438 0.7998152
## CBM:CUPP-GT:dbCAN_4 -0.8879697813 0.0000000
## CE:CUPP-GT:dbCAN_4 0.0243729246 0.8062612
## GH:CUPP-GT:dbCAN_4 0.0200313309 0.6468514
## GT:CUPP-GT:dbCAN_4 -0.0344044295 0.0000101
## PL:CUPP-GT:dbCAN_4 -0.0255551903 0.0003473
## AA:dbCAN_4:HMMER-PL:dbCAN_4 0.1047148677 1.0000000
## CBM:dbCAN_4:HMMER-PL:dbCAN_4 -0.4186971042 0.0000000
## CE:dbCAN_4:HMMER-PL:dbCAN_4 0.0609423021 1.0000000
## GH:dbCAN_4:HMMER-PL:dbCAN_4 0.0274360655 0.7903055
## GT:dbCAN_4:HMMER-PL:dbCAN_4 -0.0270476122 0.0002464
## PL:dbCAN_4:HMMER-PL:dbCAN_4 0.0911281918 1.0000000
## AA:dbCAN_4:DIAMOND-PL:dbCAN_4 0.0867166622 1.0000000
## CBM:dbCAN_4:DIAMOND-PL:dbCAN_4 -0.0154033666 0.0031018
## CE:dbCAN_4:DIAMOND-PL:dbCAN_4 0.0835352428 1.0000000
## GH:dbCAN_4:DIAMOND-PL:dbCAN_4 0.0809303470 1.0000000
## GT:dbCAN_4:DIAMOND-PL:dbCAN_4 0.0823555429 1.0000000
## PL:dbCAN_4:DIAMOND-PL:dbCAN_4 0.1159508868 0.9999999
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4 0.1059136110 1.0000000
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4 -0.0734145084 0.0000000
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4 0.0835091359 1.0000000
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4 0.0545205821 0.9999963
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4 0.0610721011 1.0000000
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4 0.0923797562 1.0000000
## AA:CUPP-PL:dbCAN_4 0.0214565172 0.4917317
## CBM:CUPP-PL:dbCAN_4 -0.8927372210 0.0000000
## CE:CUPP-PL:dbCAN_4 0.0194792696 0.4946046
## GH:CUPP-PL:dbCAN_4 0.0152638912 0.3495614
## GT:CUPP-PL:dbCAN_4 -0.0391718692 0.0000126
## PL:CUPP-PL:dbCAN_4 -0.0317230409 0.0001856
## CBM:dbCAN_4:HMMER-AA:dbCAN_4:HMMER -0.4332941410 0.0000000
## CE:dbCAN_4:HMMER-AA:dbCAN_4:HMMER 0.0463504294 0.9991902
## GH:dbCAN_4:HMMER-AA:dbCAN_4:HMMER 0.0128390287 0.2761480
## GT:dbCAN_4:HMMER-AA:dbCAN_4:HMMER -0.0416446490 0.0000061
## PL:dbCAN_4:HMMER-AA:dbCAN_4:HMMER 0.0765897790 1.0000000
## AA:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 0.0721757381 1.0000000
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER -0.0300004034 0.0001173
## CE:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 0.0689433701 1.0000000
## GH:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 0.0663333102 1.0000000
## GT:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 0.0677585061 1.0000000
## PL:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 0.1014124740 1.0000000
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 0.0913726870 1.0000000
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER -0.0880115452 0.0000000
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 0.0689172631 1.0000000
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 0.0399235453 0.9897737
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 0.0464750643 0.9993975
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 0.0778413434 1.0000000
## AA:CUPP-AA:dbCAN_4:HMMER 0.0069155931 0.1235263
## CBM:CUPP-AA:dbCAN_4:HMMER -0.9073342578 0.0000000
## CE:CUPP-AA:dbCAN_4:HMMER 0.0048873968 0.1027046
## GH:CUPP-AA:dbCAN_4:HMMER 0.0006668544 0.0554905
## GT:CUPP-AA:dbCAN_4:HMMER -0.0537689060 0.0000002
## PL:CUPP-AA:dbCAN_4:HMMER -0.0462614537 0.0000070
## CE:dbCAN_4:HMMER-CBM:dbCAN_4:HMMER 0.5496140581 0.0000000
## GH:dbCAN_4:HMMER-CBM:dbCAN_4:HMMER 0.5159816061 0.0000000
## GT:dbCAN_4:HMMER-CBM:dbCAN_4:HMMER 0.4614979284 0.0000000
## PL:dbCAN_4:HMMER-CBM:dbCAN_4:HMMER 0.5810741433 0.0000000
## AA:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 0.5766039897 0.0000000
## CBM:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 0.4731421740 0.0000000
## CE:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 0.5722069988 0.0000000
## GH:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 0.5694758876 0.0000000
## GT:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 0.5709010835 0.0000000
## PL:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 0.6058968383 0.0000000
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 0.5958009385 0.0000000
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 0.4151310322 0.0000000
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 0.5721808918 0.0000000
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 0.5430661227 0.0000000
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 0.5496176416 0.0000000
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 0.5823257077 0.0000000
## AA:CUPP-CBM:dbCAN_4:HMMER 0.5113438447 0.0000000
## CBM:CUPP-CBM:dbCAN_4:HMMER -0.4041916804 0.0000000
## CE:CUPP-CBM:dbCAN_4:HMMER 0.5081510255 0.0000000
## GH:CUPP-CBM:dbCAN_4:HMMER 0.5038094318 0.0000000
## GT:CUPP-CBM:dbCAN_4:HMMER 0.4493736714 0.0000000
## PL:CUPP-CBM:dbCAN_4:HMMER 0.4582229106 0.0000000
## GH:dbCAN_4:HMMER-CE:dbCAN_4:HMMER 0.0380421648 0.9973370
## GT:dbCAN_4:HMMER-CE:dbCAN_4:HMMER -0.0164415130 0.0015141
## PL:dbCAN_4:HMMER-CE:dbCAN_4:HMMER 0.1030084866 1.0000000
## AA:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 0.0985434971 1.0000000
## CBM:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER -0.0047972673 0.0201104
## CE:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 0.0942559243 0.9999985
## GH:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 0.0915364463 0.9999997
## GT:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 0.0929616422 0.9999987
## PL:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 0.1278311816 0.9607275
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 0.1177404459 0.9985550
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER -0.0628084091 0.0000000
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 0.0942298174 0.9999985
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 0.0651266814 1.0000000
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 0.0716782003 1.0000000
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 0.1042600510 1.0000000
## AA:CUPP-CE:dbCAN_4:HMMER 0.0332833521 0.9263877
## CBM:CUPP-CE:dbCAN_4:HMMER -0.8821311217 0.0000000
## CE:CUPP-CE:dbCAN_4:HMMER 0.0301999510 0.9419710
## GH:CUPP-CE:dbCAN_4:HMMER 0.0258699905 0.8535522
## GT:CUPP-CE:dbCAN_4:HMMER -0.0285657699 0.0000629
## PL:CUPP-CE:dbCAN_4:HMMER -0.0198427461 0.0012804
## GT:dbCAN_4:HMMER-GH:dbCAN_4:HMMER 0.0153647586 0.4409712
## PL:dbCAN_4:HMMER-GH:dbCAN_4:HMMER 0.1349409735 0.7903055
## AA:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 0.1304708199 0.8856723
## CBM:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 0.0270090043 0.8932073
## CE:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 0.1260738290 0.4360650
## GH:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 0.1233427179 0.4838913
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 0.1247679138 0.4224609
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 0.1597636686 0.0743486
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 0.1496677688 0.2422313
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER -0.0310021375 0.0000280
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 0.1260477221 0.4371639
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 0.0969329530 0.9998851
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 0.1034844719 0.9949476
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 0.1361925380 0.7501291
## AA:CUPP-GH:dbCAN_4:HMMER 0.0652106750 1.0000000
## CBM:CUPP-GH:dbCAN_4:HMMER -0.8503248501 0.0000000
## CE:CUPP-GH:dbCAN_4:HMMER 0.0620178558 1.0000000
## GH:CUPP-GH:dbCAN_4:HMMER 0.0576762621 1.0000000
## GT:CUPP-GH:dbCAN_4:HMMER 0.0032405017 0.0878901
## PL:CUPP-GH:dbCAN_4:HMMER 0.0120897408 0.2523964
## PL:dbCAN_4:HMMER-GT:dbCAN_4:HMMER 0.1894246513 0.0002464
## AA:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 0.1849544977 0.0005161
## CBM:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 0.0814926820 1.0000000
## CE:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 0.1805575068 0.0000028
## GH:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 0.1778263956 0.0000032
## GT:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 0.1792515915 0.0000021
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 0.2142473463 0.0000004
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 0.2041514465 0.0000044
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 0.0234815402 0.7859038
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 0.1805313998 0.0000029
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 0.1514166307 0.0044311
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 0.1579681497 0.0009095
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 0.1906762157 0.0001840
## AA:CUPP-GT:dbCAN_4:HMMER 0.1196943527 0.9945332
## CBM:CUPP-GT:dbCAN_4:HMMER -0.7958411724 0.0000000
## CE:CUPP-GT:dbCAN_4:HMMER 0.1165015335 0.8276371
## GH:CUPP-GT:dbCAN_4:HMMER 0.1121599398 0.9055501
## GT:CUPP-GT:dbCAN_4:HMMER 0.0577241794 1.0000000
## PL:CUPP-GT:dbCAN_4:HMMER 0.0665734186 1.0000000
## AA:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 0.0867166622 1.0000000
## CBM:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER -0.0154033666 0.0031018
## CE:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 0.0835352428 1.0000000
## GH:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 0.0809303470 1.0000000
## GT:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 0.0823555429 1.0000000
## PL:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 0.1159508868 0.9999999
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 0.1059136110 1.0000000
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER -0.0734145084 0.0000000
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 0.0835091359 1.0000000
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 0.0545205821 0.9999963
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 0.0610721011 1.0000000
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 0.0923797562 1.0000000
## AA:CUPP-PL:dbCAN_4:HMMER 0.0214565172 0.4917317
## CBM:CUPP-PL:dbCAN_4:HMMER -0.8927372210 0.0000000
## CE:CUPP-PL:dbCAN_4:HMMER 0.0194792696 0.4946046
## GH:CUPP-PL:dbCAN_4:HMMER 0.0152638912 0.3495614
## GT:CUPP-PL:dbCAN_4:HMMER -0.0391718692 0.0000126
## PL:CUPP-PL:dbCAN_4:HMMER -0.0317230409 0.0001856
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND -0.0120021979 0.0059909
## CE:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND 0.0869415756 1.0000000
## GH:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND 0.0843315157 1.0000000
## GT:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND 0.0857567116 1.0000000
## PL:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND 0.1194106795 0.9999983
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 0.1093708925 1.0000000
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND -0.0700133397 0.0000000
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 0.0869154686 1.0000000
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 0.0579217508 0.9999999
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 0.0644732698 1.0000000
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 0.0958395489 1.0000000
## AA:CUPP-AA:dbCAN_4:DIAMOND 0.0249137986 0.6147145
## CBM:CUPP-AA:dbCAN_4:DIAMOND -0.8893360523 0.0000000
## CE:CUPP-AA:dbCAN_4:DIAMOND 0.0228856023 0.6291831
## GH:CUPP-AA:dbCAN_4:DIAMOND 0.0186650599 0.4755784
## GT:CUPP-AA:dbCAN_4:DIAMOND -0.0357707005 0.0000282
## PL:CUPP-AA:dbCAN_4:DIAMOND -0.0282632482 0.0003670
## CE:dbCAN_4:DIAMOND-CBM:dbCAN_4:DIAMOND 0.1689132612 0.0000874
## GH:dbCAN_4:DIAMOND-CBM:dbCAN_4:DIAMOND 0.1661821500 0.0001020
## GT:dbCAN_4:DIAMOND-CBM:dbCAN_4:DIAMOND 0.1676073459 0.0000683
## PL:dbCAN_4:DIAMOND-CBM:dbCAN_4:DIAMOND 0.2026031007 0.0000095
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 0.1925072009 0.0000878
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 0.0118372946 0.3012306
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 0.1688871542 0.0000880
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 0.1397723851 0.0493178
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 0.1463239040 0.0136077
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 0.1790319701 0.0024018
## AA:CUPP-CBM:dbCAN_4:DIAMOND 0.1080501071 0.9999923
## CBM:CUPP-CBM:dbCAN_4:DIAMOND -0.8074854180 0.0000000
## CE:CUPP-CBM:dbCAN_4:DIAMOND 0.1048572879 0.9949018
## GH:CUPP-CBM:dbCAN_4:DIAMOND 0.1005156942 0.9988785
## GT:CUPP-CBM:dbCAN_4:DIAMOND 0.0460799338 0.9999920
## PL:CUPP-CBM:dbCAN_4:DIAMOND 0.0549291729 0.9999973
## GH:dbCAN_4:DIAMOND-CE:dbCAN_4:DIAMOND 0.0689435056 1.0000000
## GT:dbCAN_4:DIAMOND-CE:dbCAN_4:DIAMOND 0.0703687015 1.0000000
## PL:dbCAN_4:DIAMOND-CE:dbCAN_4:DIAMOND 0.1052382409 0.9999999
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 0.0951475053 1.0000000
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND -0.0854013498 0.0000000
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 0.0716368767 1.0000000
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 0.0425337407 0.9998021
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 0.0490852597 0.9999992
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 0.0816671104 1.0000000
## AA:CUPP-CE:dbCAN_4:DIAMOND 0.0106904114 0.2147568
## CBM:CUPP-CE:dbCAN_4:DIAMOND -0.9047240624 0.0000000
## CE:CUPP-CE:dbCAN_4:DIAMOND 0.0076070104 0.1681587
## GH:CUPP-CE:dbCAN_4:DIAMOND 0.0032770498 0.0878063
## GT:CUPP-CE:dbCAN_4:DIAMOND -0.0511587106 0.0000001
## PL:CUPP-CE:dbCAN_4:DIAMOND -0.0424356868 0.0000059
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND 0.0712736323 1.0000000
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND 0.1062693871 0.9999990
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 0.0961734873 1.0000000
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND -0.0844964190 0.0000000
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 0.0725534406 1.0000000
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 0.0434386715 0.9999300
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 0.0499901904 0.9999999
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 0.0826982565 1.0000000
## AA:CUPP-GH:dbCAN_4:DIAMOND 0.0117163935 0.2443009
## CBM:CUPP-GH:dbCAN_4:DIAMOND -0.9038191316 0.0000000
## CE:CUPP-GH:dbCAN_4:DIAMOND 0.0085235743 0.1937135
## GH:CUPP-GH:dbCAN_4:DIAMOND 0.0041819806 0.1025478
## GT:CUPP-GH:dbCAN_4:DIAMOND -0.0502537798 0.0000001
## PL:CUPP-GH:dbCAN_4:DIAMOND -0.0414045407 0.0000070
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4:DIAMOND 0.1048441911 0.9999998
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 0.0947482914 1.0000000
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND -0.0859216149 0.0000000
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 0.0711282447 1.0000000
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 0.0420134756 0.9998059
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 0.0485649945 0.9999993
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 0.0812730606 1.0000000
## AA:CUPP-GT:dbCAN_4:DIAMOND 0.0102911976 0.2074563
## CBM:CUPP-GT:dbCAN_4:DIAMOND -0.9052443276 0.0000000
## CE:CUPP-GT:dbCAN_4:DIAMOND 0.0070983784 0.1584778
## GH:CUPP-GT:dbCAN_4:DIAMOND 0.0027567847 0.0810541
## GT:CUPP-GT:dbCAN_4:DIAMOND -0.0516789758 0.0000000
## PL:CUPP-GT:dbCAN_4:DIAMOND -0.0428297366 0.0000048
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 0.0810909160 1.0000000
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -0.0982372034 0.0000000
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 0.0586864409 0.9999999
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 0.0296978871 0.8539543
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 0.0362494060 0.9654314
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 0.0675570612 1.0000000
## AA:CUPP-PL:dbCAN_4:DIAMOND -0.0033661778 0.0307335
## CBM:CUPP-PL:dbCAN_4:DIAMOND -0.9175599160 0.0000000
## CE:CUPP-PL:dbCAN_4:DIAMOND -0.0053434255 0.0208660
## GH:CUPP-PL:dbCAN_4:DIAMOND -0.0095588038 0.0096764
## GT:CUPP-PL:dbCAN_4:DIAMOND -0.0639945642 0.0000000
## PL:CUPP-PL:dbCAN_4:DIAMOND -0.0565457359 0.0000006
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub -0.0892102886 0.0000000
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub 0.0677185198 1.0000000
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub 0.0387248019 0.9846544
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub 0.0452763209 0.9988968
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub 0.0766426000 1.0000000
## AA:CUPP-AA:dbCAN_4:dbCAN-sub 0.0057168498 0.1066907
## CBM:CUPP-AA:dbCAN_4:dbCAN-sub -0.9085330012 0.0000000
## CE:CUPP-AA:dbCAN_4:dbCAN-sub 0.0036886534 0.0867698
## GH:CUPP-AA:dbCAN_4:dbCAN-sub -0.0005318890 0.0459620
## GT:CUPP-AA:dbCAN_4:dbCAN-sub -0.0549676494 0.0000001
## PL:CUPP-AA:dbCAN_4:dbCAN-sub -0.0474601971 0.0000052
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:dbCAN-sub 0.2268982960 0.0000000
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:dbCAN-sub 0.1977835269 0.0000000
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:dbCAN-sub 0.2043350458 0.0000000
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:dbCAN-sub 0.2370431119 0.0000000
## AA:CUPP-CBM:dbCAN_4:dbCAN-sub 0.1660612489 0.0227786
## CBM:CUPP-CBM:dbCAN_4:dbCAN-sub -0.7494742763 0.0000000
## CE:CUPP-CBM:dbCAN_4:dbCAN-sub 0.1628684296 0.0004422
## GH:CUPP-CBM:dbCAN_4:dbCAN-sub 0.1585268360 0.0007892
## GT:CUPP-CBM:dbCAN_4:dbCAN-sub 0.1040910755 0.9933760
## PL:CUPP-CBM:dbCAN_4:dbCAN-sub 0.1129403147 0.9998645
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4:dbCAN-sub 0.0425598477 0.9998055
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4:dbCAN-sub 0.0491113666 0.9999992
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4:dbCAN-sub 0.0816932173 1.0000000
## AA:CUPP-CE:dbCAN_4:dbCAN-sub 0.0107165184 0.2154043
## CBM:CUPP-CE:dbCAN_4:dbCAN-sub -0.9046979555 0.0000000
## CE:CUPP-CE:dbCAN_4:dbCAN-sub 0.0076331173 0.1687772
## GH:CUPP-CE:dbCAN_4:dbCAN-sub 0.0033031568 0.0881831
## GT:CUPP-CE:dbCAN_4:dbCAN-sub -0.0511326037 0.0000001
## PL:CUPP-CE:dbCAN_4:dbCAN-sub -0.0424095799 0.0000060
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub 0.0763999553 1.0000000
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub 0.1091080213 0.9999900
## AA:CUPP-GH:dbCAN_4:dbCAN-sub 0.0381261584 0.9814160
## CBM:CUPP-GH:dbCAN_4:dbCAN-sub -0.8774093668 0.0000000
## CE:CUPP-GH:dbCAN_4:dbCAN-sub 0.0349333391 0.9893850
## GH:CUPP-GH:dbCAN_4:dbCAN-sub 0.0305917454 0.9584596
## GT:CUPP-GH:dbCAN_4:dbCAN-sub -0.0238440150 0.0002110
## PL:CUPP-GH:dbCAN_4:dbCAN-sub -0.0149947758 0.0033688
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:dbCAN-sub 0.1025565024 1.0000000
## AA:CUPP-GT:dbCAN_4:dbCAN-sub 0.0315746394 0.9011639
## CBM:CUPP-GT:dbCAN_4:dbCAN-sub -0.8839608857 0.0000000
## CE:CUPP-GT:dbCAN_4:dbCAN-sub 0.0283818202 0.9158928
## GH:CUPP-GT:dbCAN_4:dbCAN-sub 0.0240402265 0.8056346
## GT:CUPP-GT:dbCAN_4:dbCAN-sub -0.0303955339 0.0000334
## PL:CUPP-GT:dbCAN_4:dbCAN-sub -0.0215462947 0.0008503
## AA:CUPP-PL:dbCAN_4:dbCAN-sub 0.0202049528 0.4496982
## CBM:CUPP-PL:dbCAN_4:dbCAN-sub -0.8939887855 0.0000000
## CE:CUPP-PL:dbCAN_4:dbCAN-sub 0.0182277051 0.4481108
## GH:CUPP-PL:dbCAN_4:dbCAN-sub 0.0140123268 0.3090887
## GT:CUPP-PL:dbCAN_4:dbCAN-sub -0.0404234337 0.0000091
## PL:CUPP-PL:dbCAN_4:dbCAN-sub -0.0329746054 0.0001427
## CBM:CUPP-AA:CUPP -0.8240759074 0.0000000
## CE:CUPP-AA:CUPP 0.0881457473 1.0000000
## GH:CUPP-AA:CUPP 0.0839252049 1.0000000
## GT:CUPP-AA:CUPP 0.0294894444 0.8536241
## PL:CUPP-AA:CUPP 0.0369968967 0.9256746
## CE:CUPP-CBM:CUPP 0.9821911423 0.0000000
## GH:CUPP-CBM:CUPP 0.9778495486 0.0000000
## GT:CUPP-CBM:CUPP 0.9234137881 0.0000000
## PL:CUPP-CBM:CUPP 0.9322630273 0.0000000
## GH:CUPP-CE:CUPP 0.0673330231 1.0000000
## GT:CUPP-CE:CUPP 0.0128972626 0.3341782
## PL:CUPP-CE:CUPP 0.0216202865 0.5757933
## GT:CUPP-GH:CUPP 0.0154126759 0.4430228
## PL:CUPP-GH:CUPP 0.0242619151 0.6829470
## PL:CUPP-GT:CUPP 0.0786976755 1.00000006.5.3 CAZy class precision
Two-way ANOVA to test for differences between the CAZy classes and prediction tools.
## Df Sum Sq Mean Sq F value Pr(>F)
## CAZy_class 5 15.87 3.175 278.6 <2e-16 ***
## Prediction_tool 4 11.37 2.843 249.5 <2e-16 ***
## CAZy_class:Prediction_tool 20 45.60 2.280 200.1 <2e-16 ***
## Residuals 2025 23.07 0.011
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1Statistically significant difference was detected, so follow up with a Tukey test to determine if there are differences between specific groups.
## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistic_value ~ CAZy_class * Prediction_tool, data = class_subset_prec.df)
##
## $`CAZy_class:Prediction_tool`
## diff lwr
## CBM:dbCAN_4-AA:dbCAN_4 3.642437e-02 -0.0367372855
## CE:dbCAN_4-AA:dbCAN_4 4.050330e-02 -0.0333768221
## GH:dbCAN_4-AA:dbCAN_4 6.997829e-02 -0.0031833664
## GT:dbCAN_4-AA:dbCAN_4 6.680201e-02 -0.0063596423
## PL:dbCAN_4-AA:dbCAN_4 6.474038e-02 -0.0174907778
## AA:dbCAN_4:HMMER-AA:dbCAN_4 -6.076389e-04 -0.0824048570
## CBM:dbCAN_4:HMMER-AA:dbCAN_4 -1.428083e-03 -0.0745897392
## CE:dbCAN_4:HMMER-AA:dbCAN_4 4.050330e-02 -0.0333768221
## GH:dbCAN_4:HMMER-AA:dbCAN_4 7.109534e-02 -0.0020663128
## GT:dbCAN_4:HMMER-AA:dbCAN_4 6.859706e-02 -0.0045645938
## PL:dbCAN_4:HMMER-AA:dbCAN_4 6.474038e-02 -0.0174907778
## AA:dbCAN_4:DIAMOND-AA:dbCAN_4 -2.454534e-04 -0.0820426715
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4 3.728391e-02 -0.0358777426
## CE:dbCAN_4:DIAMOND-AA:dbCAN_4 2.776121e-02 -0.0461189046
## GH:dbCAN_4:DIAMOND-AA:dbCAN_4 6.433056e-02 -0.0088310931
## GT:dbCAN_4:DIAMOND-AA:dbCAN_4 6.426168e-02 -0.0088999786
## PL:dbCAN_4:DIAMOND-AA:dbCAN_4 5.321556e-02 -0.0290156005
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4 -2.118946e-03 -0.0839161640
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4 1.776997e-02 -0.0553916815
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4 3.941141e-02 -0.0344687127
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4 6.979278e-02 -0.0033688772
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4 6.679836e-02 -0.0063632951
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4 6.474038e-02 -0.0174907778
## AA:CUPP-AA:dbCAN_4 -1.388940e-03 -0.0831861579
## CBM:CUPP-AA:dbCAN_4 -9.198237e-01 -0.9929853135
## CE:CUPP-AA:dbCAN_4 3.994508e-02 -0.0339350358
## GH:CUPP-AA:dbCAN_4 7.075353e-02 -0.0024081248
## GT:CUPP-AA:dbCAN_4 6.848319e-02 -0.0046784641
## PL:CUPP-AA:dbCAN_4 2.982173e-02 -0.0524094261
## CE:dbCAN_4-CBM:dbCAN_4 4.078926e-03 -0.0601091955
## GH:dbCAN_4-CBM:dbCAN_4 3.355392e-02 -0.0298059336
## GT:dbCAN_4-CBM:dbCAN_4 3.037764e-02 -0.0329822095
## PL:dbCAN_4-CBM:dbCAN_4 2.831601e-02 -0.0453304864
## AA:dbCAN_4:HMMER-CBM:dbCAN_4 -3.703201e-02 -0.1101936655
## CBM:dbCAN_4:HMMER-CBM:dbCAN_4 -3.785245e-02 -0.1012123064
## CE:dbCAN_4:HMMER-CBM:dbCAN_4 4.078926e-03 -0.0601091955
## GH:dbCAN_4:HMMER-CBM:dbCAN_4 3.467097e-02 -0.0286888800
## GT:dbCAN_4:HMMER-CBM:dbCAN_4 3.217269e-02 -0.0311871610
## PL:dbCAN_4:HMMER-CBM:dbCAN_4 2.831601e-02 -0.0453304864
## AA:dbCAN_4:DIAMOND-CBM:dbCAN_4 -3.666982e-02 -0.1098314800
## CBM:dbCAN_4:DIAMOND-CBM:dbCAN_4 8.595429e-04 -0.0625003098
## CE:dbCAN_4:DIAMOND-CBM:dbCAN_4 -8.663157e-03 -0.0728512780
## GH:dbCAN_4:DIAMOND-CBM:dbCAN_4 2.790619e-02 -0.0354536604
## GT:dbCAN_4:DIAMOND-CBM:dbCAN_4 2.783731e-02 -0.0355225458
## PL:dbCAN_4:DIAMOND-CBM:dbCAN_4 1.679119e-02 -0.0568553090
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 -3.854332e-02 -0.1117049724
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 -1.865440e-02 -0.0820142488
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 2.987035e-03 -0.0612010861
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 3.336841e-02 -0.0299914444
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 3.037399e-02 -0.0329858623
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 2.831601e-02 -0.0453304864
## AA:CUPP-CBM:dbCAN_4 -3.781331e-02 -0.1109749664
## CBM:CUPP-CBM:dbCAN_4 -9.562480e-01 -1.0196078807
## CE:CUPP-CBM:dbCAN_4 3.520712e-03 -0.0606674092
## GH:CUPP-CBM:dbCAN_4 3.432916e-02 -0.0290306920
## GT:CUPP-CBM:dbCAN_4 3.205882e-02 -0.0313010313
## PL:CUPP-CBM:dbCAN_4 -6.602638e-03 -0.0802491347
## GH:dbCAN_4-CE:dbCAN_4 2.947499e-02 -0.0347131279
## GT:dbCAN_4-CE:dbCAN_4 2.629872e-02 -0.0378894037
## PL:dbCAN_4-CE:dbCAN_4 2.423708e-02 -0.0501231900
## AA:dbCAN_4:HMMER-CE:dbCAN_4 -4.111094e-02 -0.1149910535
## CBM:dbCAN_4:HMMER-CE:dbCAN_4 -4.193138e-02 -0.1061195006
## CE:dbCAN_4:HMMER-CE:dbCAN_4 -6.217249e-15 -0.0650058373
## GH:dbCAN_4:HMMER-CE:dbCAN_4 3.059205e-02 -0.0335960742
## GT:dbCAN_4:HMMER-CE:dbCAN_4 2.809377e-02 -0.0360943552
## PL:dbCAN_4:HMMER-CE:dbCAN_4 2.423708e-02 -0.0501231900
## AA:dbCAN_4:DIAMOND-CE:dbCAN_4 -4.074875e-02 -0.1146288680
## CBM:dbCAN_4:DIAMOND-CE:dbCAN_4 -3.219383e-03 -0.0674075041
## CE:dbCAN_4:DIAMOND-CE:dbCAN_4 -1.274208e-02 -0.0777479197
## GH:dbCAN_4:DIAMOND-CE:dbCAN_4 2.382727e-02 -0.0403608546
## GT:dbCAN_4:DIAMOND-CE:dbCAN_4 2.375838e-02 -0.0404297401
## PL:dbCAN_4:DIAMOND-CE:dbCAN_4 1.271226e-02 -0.0616480127
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4 -4.262224e-02 -0.1165023604
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4 -2.273332e-02 -0.0869214430
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4 -1.091891e-03 -0.0660977278
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4 2.928948e-02 -0.0348986386
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4 2.629506e-02 -0.0378930565
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4 2.423708e-02 -0.0501231900
## AA:CUPP-CE:dbCAN_4 -4.189224e-02 -0.1157723544
## CBM:CUPP-CE:dbCAN_4 -9.603270e-01 -1.0245150750
## CE:CUPP-CE:dbCAN_4 -5.582137e-04 -0.0655640510
## GH:CUPP-CE:dbCAN_4 3.025023e-02 -0.0339378862
## GT:CUPP-CE:dbCAN_4 2.797990e-02 -0.0362082256
## PL:CUPP-CE:dbCAN_4 -1.068156e-02 -0.0850418383
## GT:dbCAN_4-GH:dbCAN_4 -3.176276e-03 -0.0665361285
## PL:dbCAN_4-GH:dbCAN_4 -5.237909e-03 -0.0788844054
## AA:dbCAN_4:HMMER-GH:dbCAN_4 -7.058593e-02 -0.1437475845
## CBM:dbCAN_4:HMMER-GH:dbCAN_4 -7.140637e-02 -0.1347662255
## CE:dbCAN_4:HMMER-GH:dbCAN_4 -2.947499e-02 -0.0936631146
## GH:dbCAN_4:HMMER-GH:dbCAN_4 1.117054e-03 -0.0622427991
## GT:dbCAN_4:HMMER-GH:dbCAN_4 -1.381227e-03 -0.0647410801
## PL:dbCAN_4:HMMER-GH:dbCAN_4 -5.237909e-03 -0.0788844054
## AA:dbCAN_4:DIAMOND-GH:dbCAN_4 -7.022374e-02 -0.1433853991
## CBM:dbCAN_4:DIAMOND-GH:dbCAN_4 -3.269438e-02 -0.0960542289
## CE:dbCAN_4:DIAMOND-GH:dbCAN_4 -4.221708e-02 -0.1064051971
## GH:dbCAN_4:DIAMOND-GH:dbCAN_4 -5.647727e-03 -0.0690075794
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4 -5.716612e-03 -0.0690764649
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4 -1.676273e-02 -0.0904092281
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4 -7.209724e-02 -0.1452588915
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4 -5.220832e-02 -0.1155681678
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4 -3.056688e-02 -0.0947550052
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4 -1.855107e-04 -0.0635453634
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4 -3.179929e-03 -0.0665397814
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4 -5.237909e-03 -0.0788844054
## AA:CUPP-GH:dbCAN_4 -7.136723e-02 -0.1445288855
## CBM:CUPP-GH:dbCAN_4 -9.898019e-01 -1.0531617998
## CE:CUPP-GH:dbCAN_4 -3.003321e-02 -0.0942213283
## GH:CUPP-GH:dbCAN_4 7.752416e-04 -0.0625846111
## GT:CUPP-GH:dbCAN_4 -1.495098e-03 -0.0648549504
## PL:CUPP-GH:dbCAN_4 -4.015656e-02 -0.1138030537
## PL:dbCAN_4-GT:dbCAN_4 -2.061633e-03 -0.0757081296
## AA:dbCAN_4:HMMER-GT:dbCAN_4 -6.740965e-02 -0.1405713087
## CBM:dbCAN_4:HMMER-GT:dbCAN_4 -6.823010e-02 -0.1315899496
## CE:dbCAN_4:HMMER-GT:dbCAN_4 -2.629872e-02 -0.0904868388
## GH:dbCAN_4:HMMER-GT:dbCAN_4 4.293329e-03 -0.0590665233
## GT:dbCAN_4:HMMER-GT:dbCAN_4 1.795048e-03 -0.0615648042
## PL:dbCAN_4:HMMER-GT:dbCAN_4 -2.061633e-03 -0.0757081296
## AA:dbCAN_4:DIAMOND-GT:dbCAN_4 -6.704747e-02 -0.1402091232
## CBM:dbCAN_4:DIAMOND-GT:dbCAN_4 -2.951810e-02 -0.0928779531
## CE:dbCAN_4:DIAMOND-GT:dbCAN_4 -3.904080e-02 -0.1032289212
## GH:dbCAN_4:DIAMOND-GT:dbCAN_4 -2.471451e-03 -0.0658313036
## GT:dbCAN_4:DIAMOND-GT:dbCAN_4 -2.540336e-03 -0.0659001891
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4 -1.358646e-02 -0.0872329523
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4 -6.892096e-02 -0.1420826157
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4 -4.903204e-02 -0.1123918920
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4 -2.739061e-02 -0.0915787293
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4 2.990765e-03 -0.0603690876
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4 -3.652835e-06 -0.0633635055
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4 -2.061633e-03 -0.0757081296
## AA:CUPP-GT:dbCAN_4 -6.819095e-02 -0.1413526096
## CBM:CUPP-GT:dbCAN_4 -9.866257e-01 -1.0499855240
## CE:CUPP-GT:dbCAN_4 -2.685693e-02 -0.0910450525
## GH:CUPP-GT:dbCAN_4 3.951517e-03 -0.0594083352
## GT:CUPP-GT:dbCAN_4 1.681178e-03 -0.0616786746
## PL:CUPP-GT:dbCAN_4 -3.698028e-02 -0.1106267779
## AA:dbCAN_4:HMMER-PL:dbCAN_4 -6.534802e-02 -0.1475791784
## CBM:dbCAN_4:HMMER-PL:dbCAN_4 -6.616846e-02 -0.1398149607
## CE:dbCAN_4:HMMER-PL:dbCAN_4 -2.423708e-02 -0.0985973593
## GH:dbCAN_4:HMMER-PL:dbCAN_4 6.354962e-03 -0.0672915343
## GT:dbCAN_4:HMMER-PL:dbCAN_4 3.856681e-03 -0.0697898153
## PL:dbCAN_4:HMMER-PL:dbCAN_4 -5.995204e-15 -0.0826628212
## AA:dbCAN_4:DIAMOND-PL:dbCAN_4 -6.498583e-02 -0.1472169929
## CBM:dbCAN_4:DIAMOND-PL:dbCAN_4 -2.745647e-02 -0.1011029642
## CE:dbCAN_4:DIAMOND-PL:dbCAN_4 -3.697917e-02 -0.1113394418
## GH:dbCAN_4:DIAMOND-PL:dbCAN_4 -4.098180e-04 -0.0740563147
## GT:dbCAN_4:DIAMOND-PL:dbCAN_4 -4.787035e-04 -0.0741252002
## PL:dbCAN_4:DIAMOND-PL:dbCAN_4 -1.152482e-02 -0.0941876439
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4 -6.685933e-02 -0.1490904854
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4 -4.697041e-02 -0.1206169031
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4 -2.532898e-02 -0.0996892499
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4 5.052398e-03 -0.0685940987
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4 2.057980e-03 -0.0715885166
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4 -3.219647e-15 -0.0826628212
## AA:CUPP-PL:dbCAN_4 -6.612932e-02 -0.1483604793
## CBM:CUPP-PL:dbCAN_4 -9.845640e-01 -1.0582105351
## CE:CUPP-PL:dbCAN_4 -2.479530e-02 -0.0991555730
## GH:CUPP-PL:dbCAN_4 6.013150e-03 -0.0676333463
## GT:CUPP-PL:dbCAN_4 3.742811e-03 -0.0699036857
## PL:CUPP-PL:dbCAN_4 -3.491865e-02 -0.1175814696
## CBM:dbCAN_4:HMMER-AA:dbCAN_4:HMMER -8.204443e-04 -0.0739821003
## CE:dbCAN_4:HMMER-AA:dbCAN_4:HMMER 4.111094e-02 -0.0327691832
## GH:dbCAN_4:HMMER-AA:dbCAN_4:HMMER 7.170298e-02 -0.0014586739
## GT:dbCAN_4:HMMER-AA:dbCAN_4:HMMER 6.920470e-02 -0.0039569549
## PL:dbCAN_4:HMMER-AA:dbCAN_4:HMMER 6.534802e-02 -0.0168831389
## AA:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 3.621855e-04 -0.0814350326
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 3.789155e-02 -0.0352701037
## CE:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 2.836885e-02 -0.0455112657
## GH:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 6.493820e-02 -0.0082234543
## GT:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 6.486932e-02 -0.0082923397
## PL:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 5.382320e-02 -0.0284079616
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER -1.511307e-03 -0.0833085251
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 1.837761e-02 -0.0547840427
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 4.001904e-02 -0.0338610738
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 7.040042e-02 -0.0027612383
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 6.740600e-02 -0.0057556562
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 6.534802e-02 -0.0168831389
## AA:CUPP-AA:dbCAN_4:HMMER -7.813009e-04 -0.0825785190
## CBM:CUPP-AA:dbCAN_4:HMMER -9.192160e-01 -0.9923776746
## CE:CUPP-AA:dbCAN_4:HMMER 4.055272e-02 -0.0333273969
## GH:CUPP-AA:dbCAN_4:HMMER 7.136117e-02 -0.0018004859
## GT:CUPP-AA:dbCAN_4:HMMER 6.909083e-02 -0.0040708252
## PL:CUPP-AA:dbCAN_4:HMMER 3.042937e-02 -0.0518017872
## CE:dbCAN_4:HMMER-CBM:dbCAN_4:HMMER 4.193138e-02 -0.0222567418
## GH:dbCAN_4:HMMER-CBM:dbCAN_4:HMMER 7.252343e-02 0.0091635737
## GT:dbCAN_4:HMMER-CBM:dbCAN_4:HMMER 7.002515e-02 0.0066652927
## PL:dbCAN_4:HMMER-CBM:dbCAN_4:HMMER 6.616846e-02 -0.0074780326
## AA:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 1.182630e-03 -0.0719790263
## CBM:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 3.871200e-02 -0.0246478561
## CE:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 2.918930e-02 -0.0349988243
## GH:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 6.575865e-02 0.0023987933
## GT:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 6.568976e-02 0.0023299079
## PL:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 5.464364e-02 -0.0190028553
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER -6.908627e-04 -0.0738525187
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 1.919806e-02 -0.0441617950
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 4.083949e-02 -0.0233486324
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 7.122086e-02 0.0078610093
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 6.822644e-02 0.0048665914
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 6.616846e-02 -0.0074780326
## AA:CUPP-CBM:dbCAN_4:HMMER 3.914336e-05 -0.0731225127
## CBM:CUPP-CBM:dbCAN_4:HMMER -9.183956e-01 -0.9817554270
## CE:CUPP-CBM:dbCAN_4:HMMER 4.137317e-02 -0.0228149555
## GH:CUPP-CBM:dbCAN_4:HMMER 7.218161e-02 0.0088217617
## GT:CUPP-CBM:dbCAN_4:HMMER 6.991128e-02 0.0065514224
## PL:CUPP-CBM:dbCAN_4:HMMER 3.124982e-02 -0.0423966810
## GH:dbCAN_4:HMMER-CE:dbCAN_4:HMMER 3.059205e-02 -0.0335960742
## GT:dbCAN_4:HMMER-CE:dbCAN_4:HMMER 2.809377e-02 -0.0360943552
## PL:dbCAN_4:HMMER-CE:dbCAN_4:HMMER 2.423708e-02 -0.0501231900
## AA:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER -4.074875e-02 -0.1146288680
## CBM:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER -3.219383e-03 -0.0674075041
## CE:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER -1.274208e-02 -0.0777479197
## GH:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 2.382727e-02 -0.0403608546
## GT:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 2.375838e-02 -0.0404297401
## PL:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 1.271226e-02 -0.0616480127
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER -4.262224e-02 -0.1165023604
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER -2.273332e-02 -0.0869214430
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER -1.091891e-03 -0.0660977278
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 2.928948e-02 -0.0348986386
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 2.629506e-02 -0.0378930565
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 2.423708e-02 -0.0501231900
## AA:CUPP-CE:dbCAN_4:HMMER -4.189224e-02 -0.1157723544
## CBM:CUPP-CE:dbCAN_4:HMMER -9.603270e-01 -1.0245150750
## CE:CUPP-CE:dbCAN_4:HMMER -5.582137e-04 -0.0655640510
## GH:CUPP-CE:dbCAN_4:HMMER 3.025023e-02 -0.0339378862
## GT:CUPP-CE:dbCAN_4:HMMER 2.797990e-02 -0.0362082256
## PL:CUPP-CE:dbCAN_4:HMMER -1.068156e-02 -0.0850418383
## GT:dbCAN_4:HMMER-GH:dbCAN_4:HMMER -2.498281e-03 -0.0658581337
## PL:dbCAN_4:HMMER-GH:dbCAN_4:HMMER -6.354962e-03 -0.0800014590
## AA:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER -7.134080e-02 -0.1445024527
## CBM:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER -3.381143e-02 -0.0971712825
## CE:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER -4.333413e-02 -0.1075222507
## GH:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER -6.764780e-03 -0.0701246330
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER -6.833666e-03 -0.0701935185
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER -1.787979e-02 -0.0915262817
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER -7.321429e-02 -0.1463759451
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER -5.332537e-02 -0.1166852214
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER -3.168394e-02 -0.0958720588
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER -1.302564e-03 -0.0646624171
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER -4.296982e-03 -0.0676568350
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER -6.354962e-03 -0.0800014590
## AA:CUPP-GH:dbCAN_4:HMMER -7.248428e-02 -0.1456459391
## CBM:CUPP-GH:dbCAN_4:HMMER -9.909190e-01 -1.0542788534
## CE:CUPP-GH:dbCAN_4:HMMER -3.115026e-02 -0.0953383819
## GH:CUPP-GH:dbCAN_4:HMMER -3.418120e-04 -0.0637016647
## GT:CUPP-GH:dbCAN_4:HMMER -2.612151e-03 -0.0659720040
## PL:CUPP-GH:dbCAN_4:HMMER -4.127361e-02 -0.1149201074
## PL:dbCAN_4:HMMER-GT:dbCAN_4:HMMER -3.856681e-03 -0.0775031781
## AA:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER -6.884252e-02 -0.1420041717
## CBM:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER -3.131315e-02 -0.0946730016
## CE:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER -4.083585e-02 -0.1050239697
## GH:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER -4.266499e-03 -0.0676263521
## GT:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER -4.335385e-03 -0.0676952375
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER -1.538150e-02 -0.0890280008
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER -7.071601e-02 -0.1438776641
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER -5.082709e-02 -0.1141869405
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER -2.918566e-02 -0.0933737778
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 1.195717e-03 -0.0621641361
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER -1.798701e-03 -0.0651585540
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER -3.856681e-03 -0.0775031781
## AA:CUPP-GT:dbCAN_4:HMMER -6.998600e-02 -0.1431476581
## CBM:CUPP-GT:dbCAN_4:HMMER -9.884207e-01 -1.0517805725
## CE:CUPP-GT:dbCAN_4:HMMER -2.865198e-02 -0.0928401009
## GH:CUPP-GT:dbCAN_4:HMMER 2.156469e-03 -0.0612033837
## GT:CUPP-GT:dbCAN_4:HMMER -1.138704e-04 -0.0634737231
## PL:CUPP-GT:dbCAN_4:HMMER -3.877533e-02 -0.1124218264
## AA:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER -6.498583e-02 -0.1472169929
## CBM:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER -2.745647e-02 -0.1011029642
## CE:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER -3.697917e-02 -0.1113394418
## GH:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER -4.098180e-04 -0.0740563147
## GT:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER -4.787035e-04 -0.0741252002
## PL:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER -1.152482e-02 -0.0941876439
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER -6.685933e-02 -0.1490904854
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER -4.697041e-02 -0.1206169031
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER -2.532898e-02 -0.0996892499
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 5.052398e-03 -0.0685940987
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 2.057980e-03 -0.0715885166
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 2.775558e-15 -0.0826628212
## AA:CUPP-PL:dbCAN_4:HMMER -6.612932e-02 -0.1483604793
## CBM:CUPP-PL:dbCAN_4:HMMER -9.845640e-01 -1.0582105351
## CE:CUPP-PL:dbCAN_4:HMMER -2.479530e-02 -0.0991555730
## GH:CUPP-PL:dbCAN_4:HMMER 6.013150e-03 -0.0676333463
## GT:CUPP-PL:dbCAN_4:HMMER 3.742811e-03 -0.0699036857
## PL:CUPP-PL:dbCAN_4:HMMER -3.491865e-02 -0.1175814696
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND 3.752937e-02 -0.0356322892
## CE:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND 2.800667e-02 -0.0458734511
## GH:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND 6.457602e-02 -0.0085856397
## GT:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND 6.450713e-02 -0.0086545252
## PL:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND 5.346101e-02 -0.0287701471
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND -1.873492e-03 -0.0836707106
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 1.801543e-02 -0.0551462281
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 3.965686e-02 -0.0342232592
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 7.003823e-02 -0.0031234237
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 6.704381e-02 -0.0061178417
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 6.498583e-02 -0.0172453244
## AA:CUPP-AA:dbCAN_4:DIAMOND -1.143486e-03 -0.0829407045
## CBM:CUPP-AA:dbCAN_4:DIAMOND -9.195782e-01 -0.9927398601
## CE:CUPP-AA:dbCAN_4:DIAMOND 4.019054e-02 -0.0336895824
## GH:CUPP-AA:dbCAN_4:DIAMOND 7.099898e-02 -0.0021626714
## GT:CUPP-AA:dbCAN_4:DIAMOND 6.872865e-02 -0.0044330107
## PL:CUPP-AA:dbCAN_4:DIAMOND 3.006719e-02 -0.0521639727
## CE:dbCAN_4:DIAMOND-CBM:dbCAN_4:DIAMOND -9.522700e-03 -0.0737108209
## GH:dbCAN_4:DIAMOND-CBM:dbCAN_4:DIAMOND 2.704665e-02 -0.0363132032
## GT:dbCAN_4:DIAMOND-CBM:dbCAN_4:DIAMOND 2.697776e-02 -0.0363820887
## PL:dbCAN_4:DIAMOND-CBM:dbCAN_4:DIAMOND 1.593164e-02 -0.0577148519
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND -3.940286e-02 -0.1125645153
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND -1.951394e-02 -0.0828737916
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 2.127492e-03 -0.0620606289
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 3.250887e-02 -0.0308509872
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 2.951445e-02 -0.0338454052
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 2.745647e-02 -0.0461900292
## AA:CUPP-CBM:dbCAN_4:DIAMOND -3.867285e-02 -0.1118345092
## CBM:CUPP-CBM:dbCAN_4:DIAMOND -9.571076e-01 -1.0204674236
## CE:CUPP-CBM:dbCAN_4:DIAMOND 2.661169e-03 -0.0615269521
## GH:CUPP-CBM:dbCAN_4:DIAMOND 3.346962e-02 -0.0298902349
## GT:CUPP-CBM:dbCAN_4:DIAMOND 3.119928e-02 -0.0321605742
## PL:CUPP-CBM:dbCAN_4:DIAMOND -7.462181e-03 -0.0811086775
## GH:dbCAN_4:DIAMOND-CE:dbCAN_4:DIAMOND 3.656935e-02 -0.0276187721
## GT:dbCAN_4:DIAMOND-CE:dbCAN_4:DIAMOND 3.650046e-02 -0.0276876576
## PL:dbCAN_4:DIAMOND-CE:dbCAN_4:DIAMOND 2.545434e-02 -0.0489059302
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND -2.988016e-02 -0.1037602780
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND -9.991239e-03 -0.0741793605
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 1.165019e-02 -0.0533556453
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 4.203157e-02 -0.0221565561
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 3.903715e-02 -0.0251509740
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 3.697917e-02 -0.0373811075
## AA:CUPP-CE:dbCAN_4:DIAMOND -2.915015e-02 -0.1030302719
## CBM:CUPP-CE:dbCAN_4:DIAMOND -9.475849e-01 -1.0117729925
## CE:CUPP-CE:dbCAN_4:DIAMOND 1.218387e-02 -0.0528219685
## GH:CUPP-CE:dbCAN_4:DIAMOND 4.299232e-02 -0.0211958038
## GT:CUPP-CE:dbCAN_4:DIAMOND 4.072198e-02 -0.0234661431
## PL:CUPP-CE:dbCAN_4:DIAMOND 2.060519e-03 -0.0722997559
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND -6.888547e-05 -0.0634287382
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND -1.111500e-02 -0.0847615014
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND -6.644951e-02 -0.1396111648
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND -4.656059e-02 -0.1099204411
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND -2.491916e-02 -0.0891072784
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 5.462216e-03 -0.0578976367
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 2.467798e-03 -0.0608920546
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 4.098180e-04 -0.0732366787
## AA:CUPP-GH:dbCAN_4:DIAMOND -6.571950e-02 -0.1388811587
## CBM:CUPP-GH:dbCAN_4:DIAMOND -9.841542e-01 -1.0475140731
## CE:CUPP-GH:dbCAN_4:DIAMOND -2.438548e-02 -0.0885736016
## GH:CUPP-GH:dbCAN_4:DIAMOND 6.422968e-03 -0.0569368843
## GT:CUPP-GH:dbCAN_4:DIAMOND 4.152629e-03 -0.0592072237
## PL:CUPP-GH:dbCAN_4:DIAMOND -3.450883e-02 -0.1081553270
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4:DIAMOND -1.104612e-02 -0.0846926159
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND -6.638062e-02 -0.1395422793
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND -4.649170e-02 -0.1098515556
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND -2.485027e-02 -0.0890383930
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 5.531101e-03 -0.0578287512
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 2.536684e-03 -0.0608231692
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 4.787035e-04 -0.0731677932
## AA:CUPP-GT:dbCAN_4:DIAMOND -6.565062e-02 -0.1388122732
## CBM:CUPP-GT:dbCAN_4:DIAMOND -9.840853e-01 -1.0474451876
## CE:CUPP-GT:dbCAN_4:DIAMOND -2.431659e-02 -0.0885047161
## GH:CUPP-GT:dbCAN_4:DIAMOND 6.491854e-03 -0.0568679989
## GT:CUPP-GT:dbCAN_4:DIAMOND 4.221514e-03 -0.0591383382
## PL:CUPP-GT:dbCAN_4:DIAMOND -3.443994e-02 -0.1080864415
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -5.533450e-02 -0.1375656627
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -3.544558e-02 -0.1090920804
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -1.380415e-02 -0.0881644272
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 1.657722e-02 -0.0570692760
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 1.358280e-02 -0.0600636939
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 1.152482e-02 -0.0711379985
## AA:CUPP-PL:dbCAN_4:DIAMOND -5.460450e-02 -0.1368356566
## CBM:CUPP-PL:dbCAN_4:DIAMOND -9.730392e-01 -1.0466857124
## CE:CUPP-PL:dbCAN_4:DIAMOND -1.327048e-02 -0.0876307503
## GH:CUPP-PL:dbCAN_4:DIAMOND 1.753797e-02 -0.0561085236
## GT:CUPP-PL:dbCAN_4:DIAMOND 1.526763e-02 -0.0583788630
## PL:CUPP-PL:dbCAN_4:DIAMOND -2.339383e-02 -0.1060566469
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub 1.988892e-02 -0.0532727357
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub 4.153035e-02 -0.0323497668
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub 7.191172e-02 -0.0012499313
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub 6.891731e-02 -0.0042443492
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub 6.685933e-02 -0.0153718319
## AA:CUPP-AA:dbCAN_4:dbCAN-sub 7.300061e-04 -0.0810672121
## CBM:CUPP-AA:dbCAN_4:dbCAN-sub -9.177047e-01 -0.9908663677
## CE:CUPP-AA:dbCAN_4:dbCAN-sub 4.206403e-02 -0.0318160899
## GH:CUPP-AA:dbCAN_4:dbCAN-sub 7.287248e-02 -0.0002891789
## GT:CUPP-AA:dbCAN_4:dbCAN-sub 7.060214e-02 -0.0025595183
## PL:CUPP-AA:dbCAN_4:dbCAN-sub 3.194068e-02 -0.0502904802
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:dbCAN-sub 2.164143e-02 -0.0425466900
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:dbCAN-sub 5.202280e-02 -0.0113370483
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:dbCAN-sub 4.902839e-02 -0.0143314662
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:dbCAN-sub 4.697041e-02 -0.0266760903
## AA:CUPP-CBM:dbCAN_4:dbCAN-sub -1.915891e-02 -0.0923205703
## CBM:CUPP-CBM:dbCAN_4:dbCAN-sub -9.375936e-01 -1.0009534847
## CE:CUPP-CBM:dbCAN_4:dbCAN-sub 2.217511e-02 -0.0420130132
## GH:CUPP-CBM:dbCAN_4:dbCAN-sub 5.298356e-02 -0.0103762960
## GT:CUPP-CBM:dbCAN_4:dbCAN-sub 5.071322e-02 -0.0126466353
## PL:CUPP-CBM:dbCAN_4:dbCAN-sub 1.205176e-02 -0.0615947386
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4:dbCAN-sub 3.038137e-02 -0.0338067480
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4:dbCAN-sub 2.738696e-02 -0.0368011660
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4:dbCAN-sub 2.532898e-02 -0.0490312995
## AA:CUPP-CE:dbCAN_4:dbCAN-sub -4.080035e-02 -0.1146804638
## CBM:CUPP-CE:dbCAN_4:dbCAN-sub -9.592351e-01 -1.0234231844
## CE:CUPP-CE:dbCAN_4:dbCAN-sub 5.336768e-04 -0.0644721604
## GH:CUPP-CE:dbCAN_4:dbCAN-sub 3.134213e-02 -0.0328459957
## GT:CUPP-CE:dbCAN_4:dbCAN-sub 2.907179e-02 -0.0351163350
## PL:CUPP-CE:dbCAN_4:dbCAN-sub -9.589673e-03 -0.0839499478
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub -2.994418e-03 -0.0663542706
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub -5.052398e-03 -0.0786988947
## AA:CUPP-GH:dbCAN_4:dbCAN-sub -7.118172e-02 -0.1443433747
## CBM:CUPP-GH:dbCAN_4:dbCAN-sub -9.896164e-01 -1.0529762891
## CE:CUPP-GH:dbCAN_4:dbCAN-sub -2.984770e-02 -0.0940358176
## GH:CUPP-GH:dbCAN_4:dbCAN-sub 9.607524e-04 -0.0623991003
## GT:CUPP-GH:dbCAN_4:dbCAN-sub -1.309587e-03 -0.0646694397
## PL:CUPP-GH:dbCAN_4:dbCAN-sub -3.997105e-02 -0.1136175430
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:dbCAN-sub -2.057980e-03 -0.0757044768
## AA:CUPP-GT:dbCAN_4:dbCAN-sub -6.818730e-02 -0.1413489568
## CBM:CUPP-GT:dbCAN_4:dbCAN-sub -9.866220e-01 -1.0499818711
## CE:CUPP-GT:dbCAN_4:dbCAN-sub -2.685328e-02 -0.0910413996
## GH:CUPP-GT:dbCAN_4:dbCAN-sub 3.955170e-03 -0.0594046824
## GT:CUPP-GT:dbCAN_4:dbCAN-sub 1.684831e-03 -0.0616750217
## PL:CUPP-GT:dbCAN_4:dbCAN-sub -3.697663e-02 -0.1106231251
## AA:CUPP-PL:dbCAN_4:dbCAN-sub -6.612932e-02 -0.1483604793
## CBM:CUPP-PL:dbCAN_4:dbCAN-sub -9.845640e-01 -1.0582105351
## CE:CUPP-PL:dbCAN_4:dbCAN-sub -2.479530e-02 -0.0991555730
## GH:CUPP-PL:dbCAN_4:dbCAN-sub 6.013150e-03 -0.0676333463
## GT:CUPP-PL:dbCAN_4:dbCAN-sub 3.742811e-03 -0.0699036857
## PL:CUPP-PL:dbCAN_4:dbCAN-sub -3.491865e-02 -0.1175814696
## CBM:CUPP-AA:CUPP -9.184347e-01 -0.9915963737
## CE:CUPP-AA:CUPP 4.133402e-02 -0.0325460960
## GH:CUPP-AA:CUPP 7.214247e-02 -0.0010191850
## GT:CUPP-AA:CUPP 6.987213e-02 -0.0032895243
## PL:CUPP-AA:CUPP 3.121067e-02 -0.0510204863
## CE:CUPP-CBM:CUPP 9.597687e-01 0.8955806188
## GH:CUPP-CBM:CUPP 9.905772e-01 0.9272173360
## GT:CUPP-CBM:CUPP 9.883068e-01 0.9249469967
## PL:CUPP-CBM:CUPP 9.496454e-01 0.8759988934
## GH:CUPP-CE:CUPP 3.080845e-02 -0.0333796725
## GT:CUPP-CE:CUPP 2.853811e-02 -0.0356500119
## PL:CUPP-CE:CUPP -1.012335e-02 -0.0844836246
## GT:CUPP-GH:CUPP -2.270339e-03 -0.0656301920
## PL:CUPP-GH:CUPP -4.093180e-02 -0.1145782954
## PL:CUPP-GT:CUPP -3.866146e-02 -0.1123079560
## upr p adj
## CBM:dbCAN_4-AA:dbCAN_4 1.095860e-01 0.9916783
## CE:dbCAN_4-AA:dbCAN_4 1.143834e-01 0.9692891
## GH:dbCAN_4-AA:dbCAN_4 1.431399e-01 0.0849899
## GT:dbCAN_4-AA:dbCAN_4 1.399637e-01 0.1378523
## PL:dbCAN_4-AA:dbCAN_4 1.469715e-01 0.4194292
## AA:dbCAN_4:HMMER-AA:dbCAN_4 8.118958e-02 1.0000000
## CBM:dbCAN_4:HMMER-AA:dbCAN_4 7.173357e-02 1.0000000
## CE:dbCAN_4:HMMER-AA:dbCAN_4 1.143834e-01 0.9692891
## GH:dbCAN_4:HMMER-AA:dbCAN_4 1.442570e-01 0.0709113
## GT:dbCAN_4:HMMER-AA:dbCAN_4 1.417587e-01 0.1054934
## PL:dbCAN_4:HMMER-AA:dbCAN_4 1.469715e-01 0.4194292
## AA:dbCAN_4:DIAMOND-AA:dbCAN_4 8.155176e-02 1.0000000
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4 1.104456e-01 0.9883644
## CE:dbCAN_4:DIAMOND-AA:dbCAN_4 1.016413e-01 0.9999381
## GH:dbCAN_4:DIAMOND-AA:dbCAN_4 1.374922e-01 0.1941866
## GT:dbCAN_4:DIAMOND-AA:dbCAN_4 1.374233e-01 0.1959636
## PL:dbCAN_4:DIAMOND-AA:dbCAN_4 1.354467e-01 0.8259393
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4 7.967827e-02 1.0000000
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4 9.093163e-02 1.0000000
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4 1.132915e-01 0.9783320
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4 1.429544e-01 0.0875374
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4 1.399600e-01 0.1379252
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4 1.469715e-01 0.4194292
## AA:CUPP-AA:dbCAN_4 8.040828e-02 1.0000000
## CBM:CUPP-AA:dbCAN_4 -8.466620e-01 0.0000000
## CE:CUPP-AA:dbCAN_4 1.138252e-01 0.9742183
## GH:CUPP-AA:dbCAN_4 1.439152e-01 0.0749962
## GT:CUPP-AA:dbCAN_4 1.416448e-01 0.1073476
## PL:CUPP-AA:dbCAN_4 1.120529e-01 0.9999698
## CE:dbCAN_4-CBM:dbCAN_4 6.826705e-02 1.0000000
## GH:dbCAN_4-CBM:dbCAN_4 9.691377e-02 0.9803141
## GT:dbCAN_4-CBM:dbCAN_4 9.373750e-02 0.9952779
## PL:dbCAN_4-CBM:dbCAN_4 1.019625e-01 0.9999026
## AA:dbCAN_4:HMMER-CBM:dbCAN_4 3.612965e-02 0.9894315
## CBM:dbCAN_4:HMMER-CBM:dbCAN_4 2.550740e-02 0.9180342
## CE:dbCAN_4:HMMER-CBM:dbCAN_4 6.826705e-02 1.0000000
## GH:dbCAN_4:HMMER-CBM:dbCAN_4 9.803083e-02 0.9699957
## GT:dbCAN_4:HMMER-CBM:dbCAN_4 9.553254e-02 0.9889429
## PL:dbCAN_4:HMMER-CBM:dbCAN_4 1.019625e-01 0.9999026
## AA:dbCAN_4:DIAMOND-CBM:dbCAN_4 3.649183e-02 0.9908238
## CBM:dbCAN_4:DIAMOND-CBM:dbCAN_4 6.421940e-02 1.0000000
## CE:dbCAN_4:DIAMOND-CBM:dbCAN_4 5.552496e-02 1.0000000
## GH:dbCAN_4:DIAMOND-CBM:dbCAN_4 9.126605e-02 0.9988161
## GT:dbCAN_4:DIAMOND-CBM:dbCAN_4 9.119716e-02 0.9988653
## PL:dbCAN_4:DIAMOND-CBM:dbCAN_4 9.043768e-02 1.0000000
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 3.461834e-02 0.9816331
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 4.470546e-02 0.9999997
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 6.717516e-02 1.0000000
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 9.672826e-02 0.9817144
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 9.373384e-02 0.9952866
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 1.019625e-01 0.9999026
## AA:CUPP-CBM:dbCAN_4 3.534835e-02 0.9858341
## CBM:CUPP-CBM:dbCAN_4 -8.928882e-01 0.0000000
## CE:CUPP-CBM:dbCAN_4 6.770883e-02 1.0000000
## GH:CUPP-CBM:dbCAN_4 9.768901e-02 0.9735181
## GT:CUPP-CBM:dbCAN_4 9.541867e-02 0.9894871
## PL:CUPP-CBM:dbCAN_4 6.704386e-02 1.0000000
## GH:dbCAN_4-CE:dbCAN_4 9.366311e-02 0.9976206
## GT:dbCAN_4-CE:dbCAN_4 9.048684e-02 0.9996737
## PL:dbCAN_4-CE:dbCAN_4 9.859736e-02 0.9999969
## AA:dbCAN_4:HMMER-CE:dbCAN_4 3.276918e-02 0.9631326
## CBM:dbCAN_4:HMMER-CE:dbCAN_4 2.225674e-02 0.8117598
## CE:dbCAN_4:HMMER-CE:dbCAN_4 6.500584e-02 1.0000000
## GH:dbCAN_4:HMMER-CE:dbCAN_4 9.478017e-02 0.9956941
## GT:dbCAN_4:HMMER-CE:dbCAN_4 9.228189e-02 0.9989375
## PL:dbCAN_4:HMMER-CE:dbCAN_4 9.859736e-02 0.9999969
## AA:dbCAN_4:DIAMOND-CE:dbCAN_4 3.313137e-02 0.9669052
## CBM:dbCAN_4:DIAMOND-CE:dbCAN_4 6.096874e-02 1.0000000
## CE:dbCAN_4:DIAMOND-CE:dbCAN_4 5.226375e-02 1.0000000
## GH:dbCAN_4:DIAMOND-CE:dbCAN_4 8.801539e-02 0.9999515
## GT:dbCAN_4:DIAMOND-CE:dbCAN_4 8.794650e-02 0.9999542
## PL:dbCAN_4:DIAMOND-CE:dbCAN_4 8.707254e-02 1.0000000
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4 3.125788e-02 0.9438227
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4 4.145480e-02 0.9999815
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4 6.391395e-02 1.0000000
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4 9.347760e-02 0.9978544
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4 9.048319e-02 0.9996746
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4 9.859736e-02 0.9999969
## AA:CUPP-CE:dbCAN_4 3.198788e-02 0.9538989
## CBM:CUPP-CE:dbCAN_4 -8.961388e-01 0.0000000
## CE:CUPP-CE:dbCAN_4 6.444762e-02 1.0000000
## GH:CUPP-CE:dbCAN_4 9.443836e-02 0.9963896
## GT:CUPP-CE:dbCAN_4 9.216802e-02 0.9990096
## PL:CUPP-CE:dbCAN_4 6.367871e-02 1.0000000
## GT:dbCAN_4-GH:dbCAN_4 6.018358e-02 1.0000000
## PL:dbCAN_4-GH:dbCAN_4 6.840859e-02 1.0000000
## AA:dbCAN_4:HMMER-GH:dbCAN_4 2.575728e-03 0.0770697
## CBM:dbCAN_4:HMMER-GH:dbCAN_4 -8.046520e-03 0.0084039
## CE:dbCAN_4:HMMER-GH:dbCAN_4 3.471313e-02 0.9976206
## GH:dbCAN_4:HMMER-GH:dbCAN_4 6.447691e-02 1.0000000
## GT:dbCAN_4:HMMER-GH:dbCAN_4 6.197863e-02 1.0000000
## PL:dbCAN_4:HMMER-GH:dbCAN_4 6.840859e-02 1.0000000
## AA:dbCAN_4:DIAMOND-GH:dbCAN_4 2.937913e-03 0.0817133
## CBM:dbCAN_4:DIAMOND-GH:dbCAN_4 3.066548e-02 0.9861471
## CE:dbCAN_4:DIAMOND-GH:dbCAN_4 2.197105e-02 0.8010687
## GH:dbCAN_4:DIAMOND-GH:dbCAN_4 5.771213e-02 1.0000000
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4 5.764324e-02 1.0000000
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4 5.688377e-02 1.0000000
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4 1.064421e-03 0.0599981
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4 1.115154e-02 0.3178190
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4 3.362124e-02 0.9957490
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4 6.317434e-02 1.0000000
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4 6.017992e-02 1.0000000
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4 6.840859e-02 1.0000000
## AA:CUPP-GH:dbCAN_4 1.794427e-03 0.0677967
## CBM:CUPP-GH:dbCAN_4 -9.264421e-01 0.0000000
## CE:CUPP-GH:dbCAN_4 3.415491e-02 0.9967794
## GH:CUPP-GH:dbCAN_4 6.413509e-02 1.0000000
## GT:CUPP-GH:dbCAN_4 6.186475e-02 1.0000000
## PL:CUPP-GH:dbCAN_4 3.348994e-02 0.9713059
## PL:dbCAN_4-GT:dbCAN_4 7.158486e-02 1.0000000
## AA:dbCAN_4:HMMER-GT:dbCAN_4 5.752003e-03 0.1261334
## CBM:dbCAN_4:HMMER-GT:dbCAN_4 -4.870244e-03 0.0176730
## CE:dbCAN_4:HMMER-GT:dbCAN_4 3.788940e-02 0.9996737
## GH:dbCAN_4:HMMER-GT:dbCAN_4 6.765318e-02 1.0000000
## GT:dbCAN_4:HMMER-GT:dbCAN_4 6.515490e-02 1.0000000
## PL:dbCAN_4:HMMER-GT:dbCAN_4 7.158486e-02 1.0000000
## AA:dbCAN_4:DIAMOND-GT:dbCAN_4 6.114189e-03 0.1330213
## CBM:dbCAN_4:DIAMOND-GT:dbCAN_4 3.384175e-02 0.9969939
## CE:dbCAN_4:DIAMOND-GT:dbCAN_4 2.514732e-02 0.9016362
## GH:dbCAN_4:DIAMOND-GT:dbCAN_4 6.088840e-02 1.0000000
## GT:dbCAN_4:DIAMOND-GT:dbCAN_4 6.081952e-02 1.0000000
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4 6.006004e-02 1.0000000
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4 4.240696e-03 0.1003594
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4 1.432781e-02 0.4595025
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4 3.679751e-02 0.9993183
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4 6.635062e-02 1.0000000
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4 6.335620e-02 1.0000000
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4 7.158486e-02 1.0000000
## AA:CUPP-GT:dbCAN_4 4.970702e-03 0.1122256
## CBM:CUPP-GT:dbCAN_4 -9.232658e-01 0.0000000
## CE:CUPP-GT:dbCAN_4 3.733119e-02 0.9995209
## GH:CUPP-GT:dbCAN_4 6.731137e-02 1.0000000
## GT:CUPP-GT:dbCAN_4 6.504103e-02 1.0000000
## PL:CUPP-GT:dbCAN_4 3.666622e-02 0.9905783
## AA:dbCAN_4:HMMER-PL:dbCAN_4 1.688314e-02 0.3979489
## CBM:dbCAN_4:HMMER-PL:dbCAN_4 7.478033e-03 0.1604755
## CE:dbCAN_4:HMMER-PL:dbCAN_4 5.012319e-02 0.9999969
## GH:dbCAN_4:HMMER-PL:dbCAN_4 8.000146e-02 1.0000000
## GT:dbCAN_4:HMMER-PL:dbCAN_4 7.750318e-02 1.0000000
## PL:dbCAN_4:HMMER-PL:dbCAN_4 8.266282e-02 1.0000000
## AA:dbCAN_4:DIAMOND-PL:dbCAN_4 1.724532e-02 0.4106989
## CBM:dbCAN_4:DIAMOND-PL:dbCAN_4 4.619003e-02 0.9999471
## CE:dbCAN_4:DIAMOND-PL:dbCAN_4 3.738111e-02 0.9918152
## GH:dbCAN_4:DIAMOND-PL:dbCAN_4 7.323668e-02 1.0000000
## GT:dbCAN_4:DIAMOND-PL:dbCAN_4 7.316779e-02 1.0000000
## PL:dbCAN_4:DIAMOND-PL:dbCAN_4 7.113800e-02 1.0000000
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4 1.537183e-02 0.3466648
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4 2.667609e-02 0.8464971
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4 4.903130e-02 0.9999918
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4 7.869889e-02 1.0000000
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4 7.570448e-02 1.0000000
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4 8.266282e-02 1.0000000
## AA:CUPP-PL:dbCAN_4 1.610184e-02 0.3710278
## CBM:CUPP-PL:dbCAN_4 -9.109175e-01 0.0000000
## CE:CUPP-PL:dbCAN_4 4.956498e-02 0.9999948
## GH:CUPP-PL:dbCAN_4 7.965965e-02 1.0000000
## GT:CUPP-PL:dbCAN_4 7.738931e-02 1.0000000
## PL:CUPP-PL:dbCAN_4 4.774417e-02 0.9994310
## CBM:dbCAN_4:HMMER-AA:dbCAN_4:HMMER 7.234121e-02 1.0000000
## CE:dbCAN_4:HMMER-AA:dbCAN_4:HMMER 1.149911e-01 0.9631326
## GH:dbCAN_4:HMMER-AA:dbCAN_4:HMMER 1.448646e-01 0.0641098
## GT:dbCAN_4:HMMER-AA:dbCAN_4:HMMER 1.423664e-01 0.0960293
## PL:dbCAN_4:HMMER-AA:dbCAN_4:HMMER 1.475792e-01 0.3979489
## AA:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 8.215940e-02 1.0000000
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 1.110532e-01 0.9854250
## CE:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 1.022490e-01 0.9999051
## GH:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 1.380999e-01 0.1790049
## GT:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 1.380310e-01 0.1806816
## PL:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 1.360544e-01 0.8087217
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 8.028591e-02 1.0000000
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 9.153927e-02 1.0000000
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 1.138992e-01 0.9736032
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 1.435621e-01 0.0794200
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 1.405677e-01 0.1262014
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 1.475792e-01 0.3979489
## AA:CUPP-AA:dbCAN_4:HMMER 8.101592e-02 1.0000000
## CBM:CUPP-AA:dbCAN_4:HMMER -8.460544e-01 0.0000000
## CE:CUPP-AA:dbCAN_4:HMMER 1.144328e-01 0.9688200
## GH:CUPP-AA:dbCAN_4:HMMER 1.445228e-01 0.0678648
## GT:CUPP-AA:dbCAN_4:HMMER 1.422525e-01 0.0977485
## PL:CUPP-AA:dbCAN_4:HMMER 1.126605e-01 0.9999545
## CE:dbCAN_4:HMMER-CBM:dbCAN_4:HMMER 1.061195e-01 0.8117598
## GH:dbCAN_4:HMMER-CBM:dbCAN_4:HMMER 1.358833e-01 0.0063970
## GT:dbCAN_4:HMMER-CBM:dbCAN_4:HMMER 1.333850e-01 0.0116810
## PL:dbCAN_4:HMMER-CBM:dbCAN_4:HMMER 1.398150e-01 0.1604755
## AA:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 7.434429e-02 1.0000000
## CBM:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 1.020718e-01 0.8971235
## CE:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 9.337742e-02 0.9979723
## GH:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 1.291185e-01 0.0304330
## GT:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 1.290496e-01 0.0308834
## PL:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 1.282901e-01 0.5579823
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 7.247079e-02 1.0000000
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 8.255791e-02 0.9999994
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 1.050276e-01 0.8497289
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 1.345807e-01 0.0087885
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 1.315863e-01 0.0176876
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 1.398150e-01 0.1604755
## AA:CUPP-CBM:dbCAN_4:HMMER 7.320080e-02 1.0000000
## CBM:CUPP-CBM:dbCAN_4:HMMER -8.550357e-01 0.0000000
## CE:CUPP-CBM:dbCAN_4:HMMER 1.055613e-01 0.8317573
## GH:CUPP-CBM:dbCAN_4:HMMER 1.355415e-01 0.0069584
## GT:CUPP-CBM:dbCAN_4:HMMER 1.332711e-01 0.0119975
## PL:CUPP-CBM:dbCAN_4:HMMER 1.048963e-01 0.9993834
## GH:dbCAN_4:HMMER-CE:dbCAN_4:HMMER 9.478017e-02 0.9956941
## GT:dbCAN_4:HMMER-CE:dbCAN_4:HMMER 9.228189e-02 0.9989375
## PL:dbCAN_4:HMMER-CE:dbCAN_4:HMMER 9.859736e-02 0.9999969
## AA:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 3.313137e-02 0.9669052
## CBM:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 6.096874e-02 1.0000000
## CE:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 5.226375e-02 1.0000000
## GH:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 8.801539e-02 0.9999515
## GT:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 8.794650e-02 0.9999542
## PL:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 8.707254e-02 1.0000000
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 3.125788e-02 0.9438227
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 4.145480e-02 0.9999815
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 6.391395e-02 1.0000000
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 9.347760e-02 0.9978544
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 9.048319e-02 0.9996746
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 9.859736e-02 0.9999969
## AA:CUPP-CE:dbCAN_4:HMMER 3.198788e-02 0.9538989
## CBM:CUPP-CE:dbCAN_4:HMMER -8.961388e-01 0.0000000
## CE:CUPP-CE:dbCAN_4:HMMER 6.444762e-02 1.0000000
## GH:CUPP-CE:dbCAN_4:HMMER 9.443836e-02 0.9963896
## GT:CUPP-CE:dbCAN_4:HMMER 9.216802e-02 0.9990096
## PL:CUPP-CE:dbCAN_4:HMMER 6.367871e-02 1.0000000
## GT:dbCAN_4:HMMER-GH:dbCAN_4:HMMER 6.086157e-02 1.0000000
## PL:dbCAN_4:HMMER-GH:dbCAN_4:HMMER 6.729153e-02 1.0000000
## AA:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 1.820859e-03 0.0680943
## CBM:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 2.954842e-02 0.9782307
## CE:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 2.085399e-02 0.7565199
## GH:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 5.659507e-02 1.0000000
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 5.652619e-02 1.0000000
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 5.576671e-02 1.0000000
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER -5.263307e-05 0.0495451
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 1.003448e-02 0.2742194
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 3.250418e-02 0.9926651
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 6.205729e-02 1.0000000
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 5.906287e-02 1.0000000
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 6.729153e-02 1.0000000
## AA:CUPP-GH:dbCAN_4:HMMER 6.773730e-04 0.0561815
## CBM:CUPP-GH:dbCAN_4:HMMER -9.275591e-01 0.0000000
## CE:CUPP-GH:dbCAN_4:HMMER 3.303786e-02 0.9943146
## GH:CUPP-GH:dbCAN_4:HMMER 6.301804e-02 1.0000000
## GT:CUPP-GH:dbCAN_4:HMMER 6.074770e-02 1.0000000
## PL:CUPP-GH:dbCAN_4:HMMER 3.237289e-02 0.9598428
## PL:dbCAN_4:HMMER-GT:dbCAN_4:HMMER 6.978982e-02 1.0000000
## AA:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 4.319140e-03 0.1015839
## CBM:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 3.204670e-02 0.9925319
## CE:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 2.335227e-02 0.8498475
## GH:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 5.909335e-02 1.0000000
## GT:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 5.902447e-02 1.0000000
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 5.826499e-02 1.0000000
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 2.445648e-03 0.0754563
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 1.253276e-02 0.3765998
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 3.500246e-02 0.9979764
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 6.455557e-02 1.0000000
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 6.156115e-02 1.0000000
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 6.978982e-02 1.0000000
## AA:CUPP-GT:dbCAN_4:HMMER 3.175654e-03 0.0848853
## CBM:CUPP-GT:dbCAN_4:HMMER -9.250609e-01 0.0000000
## CE:CUPP-GT:dbCAN_4:HMMER 3.553614e-02 0.9985133
## GH:CUPP-GT:dbCAN_4:HMMER 6.551632e-02 1.0000000
## GT:CUPP-GT:dbCAN_4:HMMER 6.324598e-02 1.0000000
## PL:CUPP-GT:dbCAN_4:HMMER 3.487117e-02 0.9817807
## AA:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 1.724532e-02 0.4106989
## CBM:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 4.619003e-02 0.9999471
## CE:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 3.738111e-02 0.9918152
## GH:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 7.323668e-02 1.0000000
## GT:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 7.316779e-02 1.0000000
## PL:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 7.113800e-02 1.0000000
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 1.537183e-02 0.3466648
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 2.667609e-02 0.8464971
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 4.903130e-02 0.9999918
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 7.869889e-02 1.0000000
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 7.570448e-02 1.0000000
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 8.266282e-02 1.0000000
## AA:CUPP-PL:dbCAN_4:HMMER 1.610184e-02 0.3710278
## CBM:CUPP-PL:dbCAN_4:HMMER -9.109175e-01 0.0000000
## CE:CUPP-PL:dbCAN_4:HMMER 4.956498e-02 0.9999948
## GH:CUPP-PL:dbCAN_4:HMMER 7.965965e-02 1.0000000
## GT:CUPP-PL:dbCAN_4:HMMER 7.738931e-02 1.0000000
## PL:CUPP-PL:dbCAN_4:HMMER 4.774417e-02 0.9994310
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND 1.106910e-01 0.9872415
## CE:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND 1.018868e-01 0.9999263
## GH:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND 1.377377e-01 0.1879474
## GT:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND 1.376688e-01 0.1896837
## PL:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND 1.356922e-01 0.8190877
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 7.992373e-02 1.0000000
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 9.117708e-02 1.0000000
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 1.135370e-01 0.9765096
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 1.431999e-01 0.0841799
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 1.402055e-01 0.1330922
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 1.472170e-01 0.4106989
## AA:CUPP-AA:dbCAN_4:DIAMOND 8.065373e-02 1.0000000
## CBM:CUPP-AA:dbCAN_4:DIAMOND -8.464165e-01 0.0000000
## CE:CUPP-AA:dbCAN_4:DIAMOND 1.140707e-01 0.9721329
## GH:CUPP-AA:dbCAN_4:DIAMOND 1.441606e-01 0.0720436
## GT:CUPP-AA:dbCAN_4:DIAMOND 1.418903e-01 0.1033829
## PL:CUPP-AA:dbCAN_4:DIAMOND 1.122983e-01 0.9999643
## CE:dbCAN_4:DIAMOND-CBM:dbCAN_4:DIAMOND 5.466542e-02 1.0000000
## GH:dbCAN_4:DIAMOND-CBM:dbCAN_4:DIAMOND 9.040650e-02 0.9993140
## GT:dbCAN_4:DIAMOND-CBM:dbCAN_4:DIAMOND 9.033762e-02 0.9993444
## PL:dbCAN_4:DIAMOND-CBM:dbCAN_4:DIAMOND 8.957814e-02 1.0000000
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 3.375880e-02 0.9754734
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 4.384591e-02 0.9999991
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 6.631561e-02 1.0000000
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 9.586872e-02 0.9872005
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 9.287430e-02 0.9969999
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 1.011030e-01 0.9999471
## AA:CUPP-CBM:dbCAN_4:DIAMOND 3.448880e-02 0.9807932
## CBM:CUPP-CBM:dbCAN_4:DIAMOND -8.937477e-01 0.0000000
## CE:CUPP-CBM:dbCAN_4:DIAMOND 6.684929e-02 1.0000000
## GH:CUPP-CBM:dbCAN_4:DIAMOND 9.682947e-02 0.9809606
## GT:CUPP-CBM:dbCAN_4:DIAMOND 9.455913e-02 0.9929246
## PL:CUPP-CBM:dbCAN_4:DIAMOND 6.618432e-02 1.0000000
## GH:dbCAN_4:DIAMOND-CE:dbCAN_4:DIAMOND 1.007575e-01 0.9512974
## GT:dbCAN_4:DIAMOND-CE:dbCAN_4:DIAMOND 1.006886e-01 0.9523473
## PL:dbCAN_4:DIAMOND-CE:dbCAN_4:DIAMOND 9.981462e-02 0.9999909
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 4.399996e-02 0.9997435
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 5.419688e-02 1.0000000
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 7.665603e-02 1.0000000
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 1.062197e-01 0.8080451
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 1.032253e-01 0.9017278
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 1.113394e-01 0.9918152
## AA:CUPP-CE:dbCAN_4:DIAMOND 4.472996e-02 0.9998394
## CBM:CUPP-CE:dbCAN_4:DIAMOND -8.833968e-01 0.0000000
## CE:CUPP-CE:dbCAN_4:DIAMOND 7.718971e-02 1.0000000
## GH:CUPP-CE:dbCAN_4:DIAMOND 1.071804e-01 0.7705936
## GT:CUPP-CE:dbCAN_4:DIAMOND 1.049101e-01 0.8535313
## PL:CUPP-CE:dbCAN_4:DIAMOND 7.642079e-02 1.0000000
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND 6.329097e-02 1.0000000
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND 6.253149e-02 1.0000000
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 6.712147e-03 0.1450246
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 1.679926e-02 0.5801513
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 3.926896e-02 0.9998824
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 6.882207e-02 1.0000000
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 6.582765e-02 1.0000000
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 7.405631e-02 1.0000000
## AA:CUPP-GH:dbCAN_4:DIAMOND 7.442153e-03 0.1607746
## CBM:CUPP-GH:dbCAN_4:DIAMOND -9.207944e-01 0.0000000
## CE:CUPP-GH:dbCAN_4:DIAMOND 3.980264e-02 0.9999230
## GH:CUPP-GH:dbCAN_4:DIAMOND 6.978282e-02 1.0000000
## GT:CUPP-GH:dbCAN_4:DIAMOND 6.751248e-02 1.0000000
## PL:CUPP-GH:dbCAN_4:DIAMOND 3.913767e-02 0.9967040
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4:DIAMOND 6.260038e-02 1.0000000
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 6.781033e-03 0.1464588
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 1.686815e-02 0.5835353
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 3.933785e-02 0.9998886
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 6.889095e-02 1.0000000
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 6.589654e-02 1.0000000
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 7.412520e-02 1.0000000
## AA:CUPP-GT:dbCAN_4:DIAMOND 7.511039e-03 0.1623243
## CBM:CUPP-GT:dbCAN_4:DIAMOND -9.207255e-01 0.0000000
## CE:CUPP-GT:dbCAN_4:DIAMOND 3.987153e-02 0.9999272
## GH:CUPP-GT:dbCAN_4:DIAMOND 6.985171e-02 1.0000000
## GT:CUPP-GT:dbCAN_4:DIAMOND 6.758137e-02 1.0000000
## PL:CUPP-GT:dbCAN_4:DIAMOND 3.920655e-02 0.9968073
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 2.689665e-02 0.7623718
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 3.820091e-02 0.9949899
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 6.055612e-02 1.0000000
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 9.022372e-02 1.0000000
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 8.722930e-02 1.0000000
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 9.418764e-02 1.0000000
## AA:CUPP-PL:dbCAN_4:DIAMOND 2.762666e-02 0.7853604
## CBM:CUPP-PL:dbCAN_4:DIAMOND -8.993927e-01 0.0000000
## CE:CUPP-PL:dbCAN_4:DIAMOND 6.108980e-02 1.0000000
## GH:CUPP-PL:dbCAN_4:DIAMOND 9.118447e-02 1.0000000
## GT:CUPP-PL:dbCAN_4:DIAMOND 8.891413e-02 1.0000000
## PL:CUPP-PL:dbCAN_4:DIAMOND 5.926900e-02 0.9999999
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub 9.305058e-02 1.0000000
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub 1.154105e-01 0.9583676
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub 1.450734e-01 0.0619041
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub 1.420790e-01 0.1004161
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub 1.490905e-01 0.3466648
## AA:CUPP-AA:dbCAN_4:dbCAN-sub 8.252722e-02 1.0000000
## CBM:CUPP-AA:dbCAN_4:dbCAN-sub -8.445431e-01 0.0000000
## CE:CUPP-AA:dbCAN_4:dbCAN-sub 1.159441e-01 0.9516576
## GH:CUPP-AA:dbCAN_4:dbCAN-sub 1.460341e-01 0.0525636
## GT:CUPP-AA:dbCAN_4:dbCAN-sub 1.437638e-01 0.0768671
## PL:CUPP-AA:dbCAN_4:dbCAN-sub 1.141718e-01 0.9998812
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:dbCAN-sub 8.582955e-02 0.9999935
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:dbCAN-sub 1.153827e-01 0.3254148
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:dbCAN-sub 1.123882e-01 0.4596769
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:dbCAN-sub 1.206169e-01 0.8464971
## AA:CUPP-CBM:dbCAN_4:dbCAN-sub 5.400274e-02 1.0000000
## CBM:CUPP-CBM:dbCAN_4:dbCAN-sub -8.742338e-01 0.0000000
## CE:CUPP-CBM:dbCAN_4:dbCAN-sub 8.636323e-02 0.9999890
## GH:CUPP-CBM:dbCAN_4:dbCAN-sub 1.163434e-01 0.2871614
## GT:CUPP-CBM:dbCAN_4:dbCAN-sub 1.140731e-01 0.3816616
## PL:CUPP-CBM:dbCAN_4:dbCAN-sub 8.569825e-02 1.0000000
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4:dbCAN-sub 9.456949e-02 0.9961350
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4:dbCAN-sub 9.157508e-02 0.9993199
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4:dbCAN-sub 9.968925e-02 0.9999918
## AA:CUPP-CE:dbCAN_4:dbCAN-sub 3.307977e-02 0.9663865
## CBM:CUPP-CE:dbCAN_4:dbCAN-sub -8.950469e-01 0.0000000
## CE:CUPP-CE:dbCAN_4:dbCAN-sub 6.553951e-02 1.0000000
## GH:CUPP-CE:dbCAN_4:dbCAN-sub 9.553025e-02 0.9937618
## GT:CUPP-CE:dbCAN_4:dbCAN-sub 9.325991e-02 0.9981033
## PL:CUPP-CE:dbCAN_4:dbCAN-sub 6.477060e-02 1.0000000
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub 6.036543e-02 1.0000000
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub 6.859410e-02 1.0000000
## AA:CUPP-GH:dbCAN_4:dbCAN-sub 1.979937e-03 0.0699091
## CBM:CUPP-GH:dbCAN_4:dbCAN-sub -9.262566e-01 0.0000000
## CE:CUPP-GH:dbCAN_4:dbCAN-sub 3.434042e-02 0.9970835
## GH:CUPP-GH:dbCAN_4:dbCAN-sub 6.432061e-02 1.0000000
## GT:CUPP-GH:dbCAN_4:dbCAN-sub 6.205027e-02 1.0000000
## PL:CUPP-GH:dbCAN_4:dbCAN-sub 3.367545e-02 0.9729353
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:dbCAN-sub 7.158852e-02 1.0000000
## AA:CUPP-GT:dbCAN_4:dbCAN-sub 4.974355e-03 0.1122877
## CBM:CUPP-GT:dbCAN_4:dbCAN-sub -9.232622e-01 0.0000000
## CE:CUPP-GT:dbCAN_4:dbCAN-sub 3.733484e-02 0.9995221
## GH:CUPP-GT:dbCAN_4:dbCAN-sub 6.731502e-02 1.0000000
## GT:CUPP-GT:dbCAN_4:dbCAN-sub 6.504468e-02 1.0000000
## PL:CUPP-GT:dbCAN_4:dbCAN-sub 3.666987e-02 0.9905917
## AA:CUPP-PL:dbCAN_4:dbCAN-sub 1.610184e-02 0.3710278
## CBM:CUPP-PL:dbCAN_4:dbCAN-sub -9.109175e-01 0.0000000
## CE:CUPP-PL:dbCAN_4:dbCAN-sub 4.956498e-02 0.9999948
## GH:CUPP-PL:dbCAN_4:dbCAN-sub 7.965965e-02 1.0000000
## GT:CUPP-PL:dbCAN_4:dbCAN-sub 7.738931e-02 1.0000000
## PL:CUPP-PL:dbCAN_4:dbCAN-sub 4.774417e-02 0.9994310
## CBM:CUPP-AA:CUPP -8.452731e-01 0.0000000
## CE:CUPP-AA:CUPP 1.152141e-01 0.9606523
## GH:CUPP-AA:CUPP 1.453041e-01 0.0595410
## GT:CUPP-AA:CUPP 1.430338e-01 0.0864401
## PL:CUPP-AA:CUPP 1.134418e-01 0.9999245
## CE:CUPP-CBM:CUPP 1.023957e+00 0.0000000
## GH:CUPP-CBM:CUPP 1.053937e+00 0.0000000
## GT:CUPP-CBM:CUPP 1.051667e+00 0.0000000
## PL:CUPP-CBM:CUPP 1.023292e+00 0.0000000
## GH:CUPP-CE:CUPP 9.499657e-02 0.9951975
## GT:CUPP-CE:CUPP 9.272623e-02 0.9986102
## PL:CUPP-CE:CUPP 6.423692e-02 1.0000000
## GT:CUPP-GH:CUPP 6.108951e-02 1.0000000
## PL:CUPP-GH:CUPP 3.271470e-02 0.9636643
## PL:CUPP-GT:CUPP 3.498504e-02 0.98248546.5.4 CAZy class F1-score
Two-way ANOVA to test for differences between the CAZy classes and prediction tools.
## Df Sum Sq Mean Sq F value Pr(>F)
## CAZy_class 5 30.66 6.131 549.2 <2e-16 ***
## Prediction_tool 4 13.39 3.347 299.8 <2e-16 ***
## CAZy_class:Prediction_tool 20 33.53 1.677 150.2 <2e-16 ***
## Residuals 2025 22.61 0.011
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1Statistically significant difference was detected, so follow up with a Tukey test to determine if there are differences between specific groups.
## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistic_value ~ CAZy_class * Prediction_tool, data = class_subset_f1.df)
##
## $`CAZy_class:Prediction_tool`
## diff lwr
## CBM:dbCAN_4-AA:dbCAN_4 -9.171434e-02 -0.164132274
## CE:dbCAN_4-AA:dbCAN_4 1.735107e-02 -0.055778029
## GH:dbCAN_4-AA:dbCAN_4 2.061690e-02 -0.051801032
## GT:dbCAN_4-AA:dbCAN_4 2.131309e-02 -0.051104843
## PL:dbCAN_4-AA:dbCAN_4 2.764723e-02 -0.053748018
## AA:dbCAN_4:HMMER-AA:dbCAN_4 -3.000611e-03 -0.083966325
## CBM:dbCAN_4:HMMER-AA:dbCAN_4 -3.510569e-01 -0.423474810
## CE:dbCAN_4:HMMER-AA:dbCAN_4 2.272359e-03 -0.070856737
## GH:dbCAN_4:HMMER-AA:dbCAN_4 5.196727e-03 -0.067221210
## GT:dbCAN_4:HMMER-AA:dbCAN_4 -2.938663e-02 -0.101804568
## PL:dbCAN_4:HMMER-AA:dbCAN_4 2.764723e-02 -0.053748018
## AA:dbCAN_4:DIAMOND-AA:dbCAN_4 -1.580544e-02 -0.096771158
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4 -3.927002e-02 -0.111687957
## CE:dbCAN_4:DIAMOND-AA:dbCAN_4 4.236150e-03 -0.068892945
## GH:dbCAN_4:DIAMOND-AA:dbCAN_4 2.995152e-02 -0.042466411
## GT:dbCAN_4:DIAMOND-AA:dbCAN_4 2.860856e-02 -0.043809373
## PL:dbCAN_4:DIAMOND-AA:dbCAN_4 3.601900e-02 -0.045376248
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4 -3.459494e-03 -0.084425208
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4 -8.880834e-02 -0.161226276
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4 1.527221e-02 -0.057856885
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4 1.911534e-02 -0.053302594
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4 1.994404e-02 -0.052473896
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4 2.829197e-02 -0.053103273
## AA:CUPP-AA:dbCAN_4 -4.538270e-02 -0.126348413
## CBM:CUPP-AA:dbCAN_4 -9.464340e-01 -1.018851949
## CE:CUPP-AA:dbCAN_4 -2.142267e-02 -0.094551763
## GH:CUPP-AA:dbCAN_4 -3.719642e-04 -0.072789901
## GT:CUPP-AA:dbCAN_4 -3.571804e-02 -0.108135974
## PL:CUPP-AA:dbCAN_4 -6.141646e-02 -0.142811705
## CE:dbCAN_4-CBM:dbCAN_4 1.090654e-01 0.045529783
## GH:dbCAN_4-CBM:dbCAN_4 1.123312e-01 0.049615470
## GT:dbCAN_4-CBM:dbCAN_4 1.130274e-01 0.050311658
## PL:dbCAN_4-CBM:dbCAN_4 1.193616e-01 0.046463714
## AA:dbCAN_4:HMMER-CBM:dbCAN_4 8.871373e-02 0.016295791
## CBM:dbCAN_4:HMMER-CBM:dbCAN_4 -2.593425e-01 -0.322058309
## CE:dbCAN_4:HMMER-CBM:dbCAN_4 9.398670e-02 0.030451075
## GH:dbCAN_4:HMMER-CBM:dbCAN_4 9.691106e-02 0.034195291
## GT:dbCAN_4:HMMER-CBM:dbCAN_4 6.232771e-02 -0.000388067
## PL:dbCAN_4:HMMER-CBM:dbCAN_4 1.193616e-01 0.046463714
## AA:dbCAN_4:DIAMOND-CBM:dbCAN_4 7.590889e-02 0.003490958
## CBM:dbCAN_4:DIAMOND-CBM:dbCAN_4 5.244432e-02 -0.010271456
## CE:dbCAN_4:DIAMOND-CBM:dbCAN_4 9.595049e-02 0.032414867
## GH:dbCAN_4:DIAMOND-CBM:dbCAN_4 1.216659e-01 0.058950090
## GT:dbCAN_4:DIAMOND-CBM:dbCAN_4 1.203229e-01 0.057607129
## PL:dbCAN_4:DIAMOND-CBM:dbCAN_4 1.277333e-01 0.054835484
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 8.825484e-02 0.015836907
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 2.905998e-03 -0.059809775
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 1.069865e-01 0.043450926
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 1.108297e-01 0.048113908
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 1.116584e-01 0.048942605
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 1.200063e-01 0.047108460
## AA:CUPP-CBM:dbCAN_4 4.633164e-02 -0.026086298
## CBM:CUPP-CBM:dbCAN_4 -8.547197e-01 -0.917435448
## CE:CUPP-CBM:dbCAN_4 7.029167e-02 0.006756048
## GH:CUPP-CBM:dbCAN_4 9.134237e-02 0.028626601
## GT:CUPP-CBM:dbCAN_4 5.599630e-02 -0.006719473
## PL:CUPP-CBM:dbCAN_4 3.029788e-02 -0.042599972
## GH:dbCAN_4-CE:dbCAN_4 3.265838e-03 -0.060269783
## GT:dbCAN_4-CE:dbCAN_4 3.962027e-03 -0.059573595
## PL:dbCAN_4-CE:dbCAN_4 1.029616e-02 -0.063308212
## AA:dbCAN_4:HMMER-CE:dbCAN_4 -2.035168e-02 -0.093480772
## CBM:dbCAN_4:HMMER-CE:dbCAN_4 -3.684079e-01 -0.431943562
## CE:dbCAN_4:HMMER-CE:dbCAN_4 -1.507871e-02 -0.079423733
## GH:dbCAN_4:HMMER-CE:dbCAN_4 -1.215434e-02 -0.075689961
## GT:dbCAN_4:HMMER-CE:dbCAN_4 -4.673770e-02 -0.110273320
## PL:dbCAN_4:HMMER-CE:dbCAN_4 1.029616e-02 -0.063308212
## AA:dbCAN_4:DIAMOND-CE:dbCAN_4 -3.315651e-02 -0.106285605
## CBM:dbCAN_4:DIAMOND-CE:dbCAN_4 -5.662109e-02 -0.120156709
## CE:dbCAN_4:DIAMOND-CE:dbCAN_4 -1.311492e-02 -0.077459941
## GH:dbCAN_4:DIAMOND-CE:dbCAN_4 1.260046e-02 -0.050935163
## GT:dbCAN_4:DIAMOND-CE:dbCAN_4 1.125750e-02 -0.052278124
## PL:dbCAN_4:DIAMOND-CE:dbCAN_4 1.866793e-02 -0.054936442
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4 -2.081056e-02 -0.093939655
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4 -1.061594e-01 -0.169695028
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4 -2.078856e-03 -0.066423881
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4 1.764276e-03 -0.061771345
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4 2.592974e-03 -0.060942648
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4 1.094090e-02 -0.062663467
## AA:CUPP-CE:dbCAN_4 -6.273377e-02 -0.135862861
## CBM:CUPP-CE:dbCAN_4 -9.637851e-01 -1.027320701
## CE:CUPP-CE:dbCAN_4 -3.877373e-02 -0.103118759
## GH:CUPP-CE:dbCAN_4 -1.772303e-02 -0.081258652
## GT:CUPP-CE:dbCAN_4 -5.306910e-02 -0.116604726
## PL:CUPP-CE:dbCAN_4 -7.876753e-02 -0.152371898
## GT:dbCAN_4-GH:dbCAN_4 6.961885e-04 -0.062019584
## PL:dbCAN_4-GH:dbCAN_4 7.030320e-03 -0.065867528
## AA:dbCAN_4:HMMER-GH:dbCAN_4 -2.361752e-02 -0.096035452
## CBM:dbCAN_4:HMMER-GH:dbCAN_4 -3.716738e-01 -0.434389551
## CE:dbCAN_4:HMMER-GH:dbCAN_4 -1.834455e-02 -0.081880168
## GH:dbCAN_4:HMMER-GH:dbCAN_4 -1.542018e-02 -0.078135951
## GT:dbCAN_4:HMMER-GH:dbCAN_4 -5.000354e-02 -0.112719309
## PL:dbCAN_4:HMMER-GH:dbCAN_4 7.030320e-03 -0.065867528
## AA:dbCAN_4:DIAMOND-GH:dbCAN_4 -3.642235e-02 -0.108840285
## CBM:dbCAN_4:DIAMOND-GH:dbCAN_4 -5.988693e-02 -0.122602698
## CE:dbCAN_4:DIAMOND-GH:dbCAN_4 -1.638075e-02 -0.079916376
## GH:dbCAN_4:DIAMOND-GH:dbCAN_4 9.334620e-03 -0.053381152
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4 7.991659e-03 -0.054724114
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4 1.540209e-02 -0.057495758
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4 -2.407640e-02 -0.096494335
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4 -1.094252e-01 -0.172141017
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4 -5.344695e-03 -0.068880316
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4 -1.501562e-03 -0.064217335
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4 -6.728644e-04 -0.063388637
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4 7.675066e-03 -0.065222783
## AA:CUPP-GH:dbCAN_4 -6.599960e-02 -0.138417540
## CBM:CUPP-GH:dbCAN_4 -9.670509e-01 -1.029766690
## CE:CUPP-GH:dbCAN_4 -4.203957e-02 -0.105575194
## GH:CUPP-GH:dbCAN_4 -2.098887e-02 -0.083704642
## GT:CUPP-GH:dbCAN_4 -5.633494e-02 -0.119050715
## PL:CUPP-GH:dbCAN_4 -8.203337e-02 -0.154931215
## PL:dbCAN_4-GT:dbCAN_4 6.334132e-03 -0.066563717
## AA:dbCAN_4:HMMER-GT:dbCAN_4 -2.431370e-02 -0.096731640
## CBM:dbCAN_4:HMMER-GT:dbCAN_4 -3.723700e-01 -0.435085740
## CE:dbCAN_4:HMMER-GT:dbCAN_4 -1.904073e-02 -0.082576356
## GH:dbCAN_4:HMMER-GT:dbCAN_4 -1.611637e-02 -0.078832139
## GT:dbCAN_4:HMMER-GT:dbCAN_4 -5.069973e-02 -0.113415498
## PL:dbCAN_4:HMMER-GT:dbCAN_4 6.334132e-03 -0.066563717
## AA:dbCAN_4:DIAMOND-GT:dbCAN_4 -3.711854e-02 -0.109536473
## CBM:dbCAN_4:DIAMOND-GT:dbCAN_4 -6.058311e-02 -0.123298887
## CE:dbCAN_4:DIAMOND-GT:dbCAN_4 -1.707694e-02 -0.080612564
## GH:dbCAN_4:DIAMOND-GT:dbCAN_4 8.638432e-03 -0.054077341
## GT:dbCAN_4:DIAMOND-GT:dbCAN_4 7.295471e-03 -0.055420302
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4 1.470590e-02 -0.058191946
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4 -2.477259e-02 -0.097190523
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4 -1.101214e-01 -0.172837206
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4 -6.040883e-03 -0.069576505
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4 -2.197751e-03 -0.064913523
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4 -1.369053e-03 -0.064084826
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4 6.978877e-03 -0.065918971
## AA:CUPP-GT:dbCAN_4 -6.669579e-02 -0.139113729
## CBM:CUPP-GT:dbCAN_4 -9.677471e-01 -1.030462879
## CE:CUPP-GT:dbCAN_4 -4.273576e-02 -0.106271383
## GH:CUPP-GT:dbCAN_4 -2.168506e-02 -0.084400830
## GT:CUPP-GT:dbCAN_4 -5.703113e-02 -0.119746904
## PL:CUPP-GT:dbCAN_4 -8.272955e-02 -0.155627403
## AA:dbCAN_4:HMMER-PL:dbCAN_4 -3.064784e-02 -0.112043079
## CBM:dbCAN_4:HMMER-PL:dbCAN_4 -3.787041e-01 -0.451601948
## CE:dbCAN_4:HMMER-PL:dbCAN_4 -2.537487e-02 -0.098979237
## GH:dbCAN_4:HMMER-PL:dbCAN_4 -2.245050e-02 -0.095348347
## GT:dbCAN_4:HMMER-PL:dbCAN_4 -5.703386e-02 -0.129931706
## PL:dbCAN_4:HMMER-PL:dbCAN_4 -4.440892e-15 -0.081822518
## AA:dbCAN_4:DIAMOND-PL:dbCAN_4 -4.345267e-02 -0.124847912
## CBM:dbCAN_4:DIAMOND-PL:dbCAN_4 -6.691725e-02 -0.139815094
## CE:dbCAN_4:DIAMOND-PL:dbCAN_4 -2.341107e-02 -0.097015445
## GH:dbCAN_4:DIAMOND-PL:dbCAN_4 2.304300e-03 -0.070593549
## GT:dbCAN_4:DIAMOND-PL:dbCAN_4 9.613386e-04 -0.071936510
## PL:dbCAN_4:DIAMOND-PL:dbCAN_4 8.371770e-03 -0.073450748
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4 -3.110672e-02 -0.112501963
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4 -1.164556e-01 -0.189353414
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4 -1.237502e-02 -0.085979386
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4 -8.531882e-03 -0.081429731
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4 -7.703185e-03 -0.080601033
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4 6.447453e-04 -0.081177773
## AA:CUPP-PL:dbCAN_4 -7.302992e-02 -0.154425168
## CBM:CUPP-PL:dbCAN_4 -9.740812e-01 -1.046979086
## CE:CUPP-PL:dbCAN_4 -4.906989e-02 -0.122674264
## GH:CUPP-PL:dbCAN_4 -2.801919e-02 -0.100917038
## GT:CUPP-PL:dbCAN_4 -6.336526e-02 -0.136263111
## PL:CUPP-PL:dbCAN_4 -8.906369e-02 -0.170886205
## CBM:dbCAN_4:HMMER-AA:dbCAN_4:HMMER -3.480563e-01 -0.420474200
## CE:dbCAN_4:HMMER-AA:dbCAN_4:HMMER 5.272969e-03 -0.067856126
## GH:dbCAN_4:HMMER-AA:dbCAN_4:HMMER 8.197337e-03 -0.064220599
## GT:dbCAN_4:HMMER-AA:dbCAN_4:HMMER -2.638602e-02 -0.098803958
## PL:dbCAN_4:HMMER-AA:dbCAN_4:HMMER 3.064784e-02 -0.050747408
## AA:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER -1.280483e-02 -0.093770547
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER -3.626941e-02 -0.108687347
## CE:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 7.236761e-03 -0.065892334
## GH:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 3.295214e-02 -0.039465801
## GT:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 3.160917e-02 -0.040808762
## PL:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 3.901961e-02 -0.042375638
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER -4.588832e-04 -0.081424598
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER -8.580773e-02 -0.158225666
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 1.827282e-02 -0.054856275
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 2.211595e-02 -0.050301983
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 2.294465e-02 -0.049473286
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 3.129258e-02 -0.050102663
## AA:CUPP-AA:dbCAN_4:HMMER -4.238209e-02 -0.123347803
## CBM:CUPP-AA:dbCAN_4:HMMER -9.434334e-01 -1.015851339
## CE:CUPP-AA:dbCAN_4:HMMER -1.842206e-02 -0.091551153
## GH:CUPP-AA:dbCAN_4:HMMER 2.628646e-03 -0.069789290
## GT:CUPP-AA:dbCAN_4:HMMER -3.271743e-02 -0.105135364
## PL:CUPP-AA:dbCAN_4:HMMER -5.841585e-02 -0.139811094
## CE:dbCAN_4:HMMER-CBM:dbCAN_4:HMMER 3.533292e-01 0.289793611
## GH:dbCAN_4:HMMER-CBM:dbCAN_4:HMMER 3.562536e-01 0.293537828
## GT:dbCAN_4:HMMER-CBM:dbCAN_4:HMMER 3.216702e-01 0.258954470
## PL:dbCAN_4:HMMER-CBM:dbCAN_4:HMMER 3.787041e-01 0.305806251
## AA:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 3.352514e-01 0.262833494
## CBM:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 3.117869e-01 0.249071081
## CE:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 3.552930e-01 0.291757403
## GH:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 3.810084e-01 0.318292626
## GT:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 3.796654e-01 0.316949665
## PL:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 3.870759e-01 0.314178021
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 3.475974e-01 0.275179444
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 2.622485e-01 0.199532762
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 3.663291e-01 0.302793463
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 3.701722e-01 0.307456444
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 3.710009e-01 0.308285142
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 3.793488e-01 0.306450996
## AA:CUPP-CBM:dbCAN_4:HMMER 3.056742e-01 0.233256239
## CBM:CUPP-CBM:dbCAN_4:HMMER -5.953771e-01 -0.658092911
## CE:CUPP-CBM:dbCAN_4:HMMER 3.296342e-01 0.266098585
## GH:CUPP-CBM:dbCAN_4:HMMER 3.506849e-01 0.287969137
## GT:CUPP-CBM:dbCAN_4:HMMER 3.153388e-01 0.252623064
## PL:CUPP-CBM:dbCAN_4:HMMER 2.896404e-01 0.216742564
## GH:dbCAN_4:HMMER-CE:dbCAN_4:HMMER 2.924368e-03 -0.060611254
## GT:dbCAN_4:HMMER-CE:dbCAN_4:HMMER -3.165899e-02 -0.095194612
## PL:dbCAN_4:HMMER-CE:dbCAN_4:HMMER 2.537487e-02 -0.048229504
## AA:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER -1.807780e-02 -0.091206897
## CBM:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER -4.154238e-02 -0.105078001
## CE:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 1.963792e-03 -0.062381233
## GH:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 2.767917e-02 -0.035856455
## GT:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 2.633621e-02 -0.037199416
## PL:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 3.374664e-02 -0.039857734
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER -5.731852e-03 -0.078860948
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER -9.108070e-02 -0.154616320
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 1.299985e-02 -0.051345174
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 1.684298e-02 -0.046692637
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 1.767168e-02 -0.045863940
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 2.601961e-02 -0.047584759
## AA:CUPP-CE:dbCAN_4:HMMER -4.765506e-02 -0.120784153
## CBM:CUPP-CE:dbCAN_4:HMMER -9.487064e-01 -1.012241993
## CE:CUPP-CE:dbCAN_4:HMMER -2.369503e-02 -0.088040052
## GH:CUPP-CE:dbCAN_4:HMMER -2.644323e-03 -0.066179944
## GT:CUPP-CE:dbCAN_4:HMMER -3.799040e-02 -0.101526018
## PL:CUPP-CE:dbCAN_4:HMMER -6.368882e-02 -0.137293191
## GT:dbCAN_4:HMMER-GH:dbCAN_4:HMMER -3.458336e-02 -0.097299131
## PL:dbCAN_4:HMMER-GH:dbCAN_4:HMMER 2.245050e-02 -0.050447350
## AA:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER -2.100217e-02 -0.093420106
## CBM:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER -4.446675e-02 -0.107182520
## CE:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER -9.605761e-04 -0.064496198
## GH:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 2.475480e-02 -0.037960974
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 2.341184e-02 -0.039303935
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 3.082227e-02 -0.042075580
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER -8.656220e-03 -0.081074157
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER -9.400507e-02 -0.156720839
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 1.007548e-02 -0.053460138
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 1.391862e-02 -0.048797156
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 1.474731e-02 -0.047968459
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 2.309524e-02 -0.049802604
## AA:CUPP-GH:dbCAN_4:HMMER -5.057943e-02 -0.122997362
## CBM:CUPP-GH:dbCAN_4:HMMER -9.516307e-01 -1.014346512
## CE:CUPP-GH:dbCAN_4:HMMER -2.661939e-02 -0.090155016
## GH:CUPP-GH:dbCAN_4:HMMER -5.568691e-03 -0.068284463
## GT:CUPP-GH:dbCAN_4:HMMER -4.091476e-02 -0.103630537
## PL:CUPP-GH:dbCAN_4:HMMER -6.661319e-02 -0.139511036
## PL:dbCAN_4:HMMER-GT:dbCAN_4:HMMER 5.703386e-02 -0.015863991
## AA:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 1.358119e-02 -0.058836748
## CBM:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER -9.883389e-03 -0.072599161
## CE:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 3.362278e-02 -0.029912839
## GH:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 5.933816e-02 -0.003377616
## GT:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 5.799520e-02 -0.004720577
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 6.540563e-02 -0.007492221
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 2.592714e-02 -0.046490798
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER -5.942171e-02 -0.122137481
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 4.465884e-02 -0.018876779
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 4.850197e-02 -0.014213798
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 4.933067e-02 -0.013385100
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 5.767860e-02 -0.015219246
## AA:CUPP-GT:dbCAN_4:HMMER -1.599607e-02 -0.088414004
## CBM:CUPP-GT:dbCAN_4:HMMER -9.170474e-01 -0.979763153
## CE:CUPP-GT:dbCAN_4:HMMER 7.963964e-03 -0.055571657
## GH:CUPP-GT:dbCAN_4:HMMER 2.901467e-02 -0.033701105
## GT:CUPP-GT:dbCAN_4:HMMER -6.331406e-03 -0.069047179
## PL:CUPP-GT:dbCAN_4:HMMER -3.202983e-02 -0.104927678
## AA:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER -4.345267e-02 -0.124847912
## CBM:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER -6.691725e-02 -0.139815094
## CE:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER -2.341107e-02 -0.097015445
## GH:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 2.304300e-03 -0.070593549
## GT:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 9.613386e-04 -0.071936510
## PL:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 8.371770e-03 -0.073450748
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER -3.110672e-02 -0.112501963
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER -1.164556e-01 -0.189353414
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER -1.237502e-02 -0.085979386
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER -8.531882e-03 -0.081429731
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER -7.703185e-03 -0.080601033
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 6.447453e-04 -0.081177773
## AA:CUPP-PL:dbCAN_4:HMMER -7.302992e-02 -0.154425168
## CBM:CUPP-PL:dbCAN_4:HMMER -9.740812e-01 -1.046979086
## CE:CUPP-PL:dbCAN_4:HMMER -4.906989e-02 -0.122674264
## GH:CUPP-PL:dbCAN_4:HMMER -2.801919e-02 -0.100917038
## GT:CUPP-PL:dbCAN_4:HMMER -6.336526e-02 -0.136263111
## PL:CUPP-PL:dbCAN_4:HMMER -8.906369e-02 -0.170886205
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND -2.346458e-02 -0.095882514
## CE:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND 2.004159e-02 -0.053087501
## GH:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND 4.575697e-02 -0.026660968
## GT:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND 4.441401e-02 -0.028003929
## PL:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND 5.182444e-02 -0.029570805
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 1.234595e-02 -0.068619765
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND -7.300290e-02 -0.145420833
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 3.107765e-02 -0.042051442
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 3.492079e-02 -0.037497150
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 3.574948e-02 -0.036668453
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 4.409741e-02 -0.037297830
## AA:CUPP-AA:dbCAN_4:DIAMOND -2.957726e-02 -0.110542970
## CBM:CUPP-AA:dbCAN_4:DIAMOND -9.306286e-01 -1.003046506
## CE:CUPP-AA:dbCAN_4:DIAMOND -5.617224e-03 -0.078746320
## GH:CUPP-AA:dbCAN_4:DIAMOND 1.543348e-02 -0.056984457
## GT:CUPP-AA:dbCAN_4:DIAMOND -1.991259e-02 -0.092330531
## PL:CUPP-AA:dbCAN_4:DIAMOND -4.561102e-02 -0.127006262
## CE:dbCAN_4:DIAMOND-CBM:dbCAN_4:DIAMOND 4.350617e-02 -0.020029450
## GH:dbCAN_4:DIAMOND-CBM:dbCAN_4:DIAMOND 6.922155e-02 0.006505773
## GT:dbCAN_4:DIAMOND-CBM:dbCAN_4:DIAMOND 6.787858e-02 0.005162812
## PL:dbCAN_4:DIAMOND-CBM:dbCAN_4:DIAMOND 7.528902e-02 0.002391167
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 3.581053e-02 -0.036607410
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND -4.953832e-02 -0.112254092
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 5.454223e-02 -0.008993391
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 5.838536e-02 -0.004330409
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 5.921406e-02 -0.003501712
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 6.756199e-02 -0.005335857
## AA:CUPP-CBM:dbCAN_4:DIAMOND -6.112678e-03 -0.078530615
## CBM:CUPP-CBM:dbCAN_4:DIAMOND -9.071640e-01 -0.969879765
## CE:CUPP-CBM:dbCAN_4:DIAMOND 1.784735e-02 -0.045688269
## GH:CUPP-CBM:dbCAN_4:DIAMOND 3.889806e-02 -0.023817716
## GT:CUPP-CBM:dbCAN_4:DIAMOND 3.551983e-03 -0.059163790
## PL:CUPP-CBM:dbCAN_4:DIAMOND -2.214644e-02 -0.095044289
## GH:dbCAN_4:DIAMOND-CE:dbCAN_4:DIAMOND 2.571537e-02 -0.037820247
## GT:dbCAN_4:DIAMOND-CE:dbCAN_4:DIAMOND 2.437241e-02 -0.039163208
## PL:dbCAN_4:DIAMOND-CE:dbCAN_4:DIAMOND 3.178284e-02 -0.041821526
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND -7.695644e-03 -0.080824739
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND -9.304449e-02 -0.156580112
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 1.103606e-02 -0.053308965
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 1.487919e-02 -0.048656429
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 1.570789e-02 -0.047827732
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 2.405582e-02 -0.049548551
## AA:CUPP-CE:dbCAN_4:DIAMOND -4.961885e-02 -0.122747945
## CBM:CUPP-CE:dbCAN_4:DIAMOND -9.506702e-01 -1.014205785
## CE:CUPP-CE:dbCAN_4:DIAMOND -2.565882e-02 -0.090003843
## GH:CUPP-CE:dbCAN_4:DIAMOND -4.608115e-03 -0.068143736
## GT:CUPP-CE:dbCAN_4:DIAMOND -3.995419e-02 -0.103489810
## PL:CUPP-CE:dbCAN_4:DIAMOND -6.565261e-02 -0.139256982
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND -1.342961e-03 -0.064058734
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND 6.067470e-03 -0.066830378
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND -3.341102e-02 -0.105828955
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND -1.187599e-01 -0.181475638
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND -1.467931e-02 -0.078214936
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND -1.083618e-02 -0.073551955
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND -1.000748e-02 -0.072723257
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND -1.659554e-03 -0.074557403
## AA:CUPP-GH:dbCAN_4:DIAMOND -7.533422e-02 -0.147752160
## CBM:CUPP-GH:dbCAN_4:DIAMOND -9.763855e-01 -1.039101310
## CE:CUPP-GH:dbCAN_4:DIAMOND -5.137419e-02 -0.114909814
## GH:CUPP-GH:dbCAN_4:DIAMOND -3.032349e-02 -0.093039262
## GT:CUPP-GH:dbCAN_4:DIAMOND -6.566956e-02 -0.128385335
## PL:CUPP-GH:dbCAN_4:DIAMOND -9.136799e-02 -0.164265835
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4:DIAMOND 7.410431e-03 -0.065487417
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND -3.206806e-02 -0.104485994
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND -1.174169e-01 -0.180132676
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND -1.333635e-02 -0.076871975
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND -9.493221e-03 -0.072208994
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND -8.664523e-03 -0.071380296
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND -3.165933e-04 -0.073214442
## AA:CUPP-GT:dbCAN_4:DIAMOND -7.399126e-02 -0.146409199
## CBM:CUPP-GT:dbCAN_4:DIAMOND -9.750426e-01 -1.037758349
## CE:CUPP-GT:dbCAN_4:DIAMOND -5.003123e-02 -0.113566853
## GH:CUPP-GT:dbCAN_4:DIAMOND -2.898053e-02 -0.091696301
## GT:CUPP-GT:dbCAN_4:DIAMOND -6.432660e-02 -0.127042374
## PL:CUPP-GT:dbCAN_4:DIAMOND -9.002503e-02 -0.162922874
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -3.947849e-02 -0.120873733
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -1.248273e-01 -0.197725184
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -2.074679e-02 -0.094351156
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -1.690365e-02 -0.089801501
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -1.607495e-02 -0.088972803
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -7.727025e-03 -0.089549543
## AA:CUPP-PL:dbCAN_4:DIAMOND -8.140169e-02 -0.162796938
## CBM:CUPP-PL:dbCAN_4:DIAMOND -9.824530e-01 -1.055350856
## CE:CUPP-PL:dbCAN_4:DIAMOND -5.744166e-02 -0.131046034
## GH:CUPP-PL:dbCAN_4:DIAMOND -3.639096e-02 -0.109288808
## GT:CUPP-PL:dbCAN_4:DIAMOND -7.173703e-02 -0.144634882
## PL:CUPP-PL:dbCAN_4:DIAMOND -9.743546e-02 -0.179257975
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub -8.534885e-02 -0.157766783
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub 1.873170e-02 -0.054397391
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub 2.257484e-02 -0.049843100
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub 2.340353e-02 -0.049014402
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub 3.175146e-02 -0.049643779
## AA:CUPP-AA:dbCAN_4:dbCAN-sub -4.192321e-02 -0.122888920
## CBM:CUPP-AA:dbCAN_4:dbCAN-sub -9.429745e-01 -1.015392455
## CE:CUPP-AA:dbCAN_4:dbCAN-sub -1.796317e-02 -0.091092269
## GH:CUPP-AA:dbCAN_4:dbCAN-sub 3.087530e-03 -0.069330407
## GT:CUPP-AA:dbCAN_4:dbCAN-sub -3.225854e-02 -0.104676481
## PL:CUPP-AA:dbCAN_4:dbCAN-sub -5.795697e-02 -0.139352211
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:dbCAN-sub 1.040806e-01 0.040544929
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:dbCAN-sub 1.079237e-01 0.045207910
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:dbCAN-sub 1.087524e-01 0.046036608
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:dbCAN-sub 1.171003e-01 0.044202462
## AA:CUPP-CBM:dbCAN_4:dbCAN-sub 4.342564e-02 -0.028992296
## CBM:CUPP-CBM:dbCAN_4:dbCAN-sub -8.576257e-01 -0.920341445
## CE:CUPP-CBM:dbCAN_4:dbCAN-sub 6.738567e-02 0.003850051
## GH:CUPP-CBM:dbCAN_4:dbCAN-sub 8.843638e-02 0.025720603
## GT:CUPP-CBM:dbCAN_4:dbCAN-sub 5.309030e-02 -0.009625471
## PL:CUPP-CBM:dbCAN_4:dbCAN-sub 2.739188e-02 -0.045505970
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4:dbCAN-sub 3.843133e-03 -0.059692489
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4:dbCAN-sub 4.671830e-03 -0.058863791
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4:dbCAN-sub 1.301976e-02 -0.060584610
## AA:CUPP-CE:dbCAN_4:dbCAN-sub -6.065491e-02 -0.133784004
## CBM:CUPP-CE:dbCAN_4:dbCAN-sub -9.617062e-01 -1.025241844
## CE:CUPP-CE:dbCAN_4:dbCAN-sub -3.669488e-02 -0.101039903
## GH:CUPP-CE:dbCAN_4:dbCAN-sub -1.564417e-02 -0.079179796
## GT:CUPP-CE:dbCAN_4:dbCAN-sub -5.099025e-02 -0.114525869
## PL:CUPP-CE:dbCAN_4:dbCAN-sub -7.668867e-02 -0.150293042
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub 8.286977e-04 -0.061887075
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub 9.176628e-03 -0.063721221
## AA:CUPP-GH:dbCAN_4:dbCAN-sub -6.449804e-02 -0.136915978
## CBM:CUPP-GH:dbCAN_4:dbCAN-sub -9.655494e-01 -1.028265128
## CE:CUPP-GH:dbCAN_4:dbCAN-sub -4.053801e-02 -0.104073632
## GH:CUPP-GH:dbCAN_4:dbCAN-sub -1.948731e-02 -0.082203080
## GT:CUPP-GH:dbCAN_4:dbCAN-sub -5.483338e-02 -0.117549153
## PL:CUPP-GH:dbCAN_4:dbCAN-sub -8.053180e-02 -0.153429653
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:dbCAN-sub 8.347930e-03 -0.064549918
## AA:CUPP-GT:dbCAN_4:dbCAN-sub -6.532674e-02 -0.137744676
## CBM:CUPP-GT:dbCAN_4:dbCAN-sub -9.663781e-01 -1.029093826
## CE:CUPP-GT:dbCAN_4:dbCAN-sub -4.136671e-02 -0.104902330
## GH:CUPP-GT:dbCAN_4:dbCAN-sub -2.031600e-02 -0.083031777
## GT:CUPP-GT:dbCAN_4:dbCAN-sub -5.566208e-02 -0.118377851
## PL:CUPP-GT:dbCAN_4:dbCAN-sub -8.136050e-02 -0.154258350
## AA:CUPP-PL:dbCAN_4:dbCAN-sub -7.367467e-02 -0.155069913
## CBM:CUPP-PL:dbCAN_4:dbCAN-sub -9.747260e-01 -1.047623832
## CE:CUPP-PL:dbCAN_4:dbCAN-sub -4.971464e-02 -0.123319009
## GH:CUPP-PL:dbCAN_4:dbCAN-sub -2.866393e-02 -0.101561783
## GT:CUPP-PL:dbCAN_4:dbCAN-sub -6.401001e-02 -0.136907857
## PL:CUPP-PL:dbCAN_4:dbCAN-sub -8.970843e-02 -0.171530950
## CBM:CUPP-AA:CUPP -9.010513e-01 -0.973469250
## CE:CUPP-AA:CUPP 2.396003e-02 -0.049169064
## GH:CUPP-AA:CUPP 4.501073e-02 -0.027407202
## GT:CUPP-AA:CUPP 9.664661e-03 -0.062753275
## PL:CUPP-AA:CUPP -1.603376e-02 -0.097429006
## CE:CUPP-CBM:CUPP 9.250113e-01 0.861475723
## GH:CUPP-CBM:CUPP 9.460620e-01 0.883346276
## GT:CUPP-CBM:CUPP 9.107160e-01 0.848000202
## PL:CUPP-CBM:CUPP 8.850176e-01 0.812119703
## GH:CUPP-CE:CUPP 2.105070e-02 -0.042484918
## GT:CUPP-CE:CUPP -1.429537e-02 -0.077830991
## PL:CUPP-CE:CUPP -3.999379e-02 -0.113598164
## GT:CUPP-GH:CUPP -3.534607e-02 -0.098061846
## PL:CUPP-GH:CUPP -6.104450e-02 -0.133942346
## PL:CUPP-GT:CUPP -2.569842e-02 -0.098596272
## upr p adj
## CBM:dbCAN_4-AA:dbCAN_4 -1.929640e-02 0.0008343
## CE:dbCAN_4-AA:dbCAN_4 9.048016e-02 1.0000000
## GH:dbCAN_4-AA:dbCAN_4 9.303484e-02 0.9999999
## GT:dbCAN_4-AA:dbCAN_4 9.373103e-02 0.9999997
## PL:dbCAN_4-AA:dbCAN_4 1.090425e-01 0.9999923
## AA:dbCAN_4:HMMER-AA:dbCAN_4 7.796510e-02 1.0000000
## CBM:dbCAN_4:HMMER-AA:dbCAN_4 -2.786389e-01 0.0000000
## CE:dbCAN_4:HMMER-AA:dbCAN_4 7.540145e-02 1.0000000
## GH:dbCAN_4:HMMER-AA:dbCAN_4 7.761466e-02 1.0000000
## GT:dbCAN_4:HMMER-AA:dbCAN_4 4.303130e-02 0.9997271
## PL:dbCAN_4:HMMER-AA:dbCAN_4 1.090425e-01 0.9999923
## AA:dbCAN_4:DIAMOND-AA:dbCAN_4 6.516027e-02 1.0000000
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4 3.314792e-02 0.9732329
## CE:dbCAN_4:DIAMOND-AA:dbCAN_4 7.736525e-02 1.0000000
## GH:dbCAN_4:DIAMOND-AA:dbCAN_4 1.023695e-01 0.9996120
## GT:dbCAN_4:DIAMOND-AA:dbCAN_4 1.010265e-01 0.9998355
## PL:dbCAN_4:DIAMOND-AA:dbCAN_4 1.174142e-01 0.9987168
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4 7.750622e-02 1.0000000
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4 -1.639040e-02 0.0016786
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4 8.840131e-02 1.0000000
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4 9.153328e-02 1.0000000
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4 9.236198e-02 0.9999999
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4 1.096872e-01 0.9999875
## AA:CUPP-AA:dbCAN_4 3.558302e-02 0.9597668
## CBM:CUPP-AA:dbCAN_4 -8.740161e-01 0.0000000
## CE:CUPP-AA:dbCAN_4 5.170643e-02 0.9999997
## GH:CUPP-AA:dbCAN_4 7.204597e-02 1.0000000
## GT:CUPP-AA:dbCAN_4 3.669990e-02 0.9927505
## PL:CUPP-AA:dbCAN_4 1.997878e-02 0.5188266
## CE:dbCAN_4-CBM:dbCAN_4 1.726010e-01 0.0000001
## GH:dbCAN_4-CBM:dbCAN_4 1.750470e-01 0.0000000
## GT:dbCAN_4-CBM:dbCAN_4 1.757432e-01 0.0000000
## PL:dbCAN_4-CBM:dbCAN_4 1.922594e-01 0.0000004
## AA:dbCAN_4:HMMER-CBM:dbCAN_4 1.611317e-01 0.0017165
## CBM:dbCAN_4:HMMER-CBM:dbCAN_4 -1.966268e-01 0.0000000
## CE:dbCAN_4:HMMER-CBM:dbCAN_4 1.575223e-01 0.0000134
## GH:dbCAN_4:HMMER-CBM:dbCAN_4 1.596268e-01 0.0000033
## GT:dbCAN_4:HMMER-CBM:dbCAN_4 1.250435e-01 0.0540626
## PL:dbCAN_4:HMMER-CBM:dbCAN_4 1.922594e-01 0.0000004
## AA:dbCAN_4:DIAMOND-CBM:dbCAN_4 1.483268e-01 0.0264290
## CBM:dbCAN_4:DIAMOND-CBM:dbCAN_4 1.151601e-01 0.2871862
## CE:dbCAN_4:DIAMOND-CBM:dbCAN_4 1.594861e-01 0.0000070
## GH:dbCAN_4:DIAMOND-CBM:dbCAN_4 1.843816e-01 0.0000000
## GT:dbCAN_4:DIAMOND-CBM:dbCAN_4 1.830387e-01 0.0000000
## PL:dbCAN_4:DIAMOND-CBM:dbCAN_4 2.006312e-01 0.0000000
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 1.606728e-01 0.0019119
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 6.562177e-02 1.0000000
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 1.705222e-01 0.0000001
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 1.735455e-01 0.0000000
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 1.743742e-01 0.0000000
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 1.929042e-01 0.0000003
## AA:CUPP-CBM:dbCAN_4 1.187496e-01 0.8422290
## CBM:CUPP-CBM:dbCAN_4 -7.920039e-01 0.0000000
## CE:CUPP-CBM:dbCAN_4 1.338273e-01 0.0114846
## GH:CUPP-CBM:dbCAN_4 1.540581e-01 0.0000216
## GT:CUPP-CBM:dbCAN_4 1.187121e-01 0.1698467
## PL:CUPP-CBM:dbCAN_4 1.031957e-01 0.9995757
## GH:dbCAN_4-CE:dbCAN_4 6.680146e-02 1.0000000
## GT:dbCAN_4-CE:dbCAN_4 6.749765e-02 1.0000000
## PL:dbCAN_4-CE:dbCAN_4 8.390053e-02 1.0000000
## AA:dbCAN_4:HMMER-CE:dbCAN_4 5.277742e-02 0.9999999
## CBM:dbCAN_4:HMMER-CE:dbCAN_4 -3.048723e-01 0.0000000
## CE:dbCAN_4:HMMER-CE:dbCAN_4 4.926632e-02 1.0000000
## GH:dbCAN_4:HMMER-CE:dbCAN_4 5.138128e-02 1.0000000
## GT:dbCAN_4:HMMER-CE:dbCAN_4 1.679792e-02 0.5778015
## PL:dbCAN_4:HMMER-CE:dbCAN_4 8.390053e-02 1.0000000
## AA:dbCAN_4:DIAMOND-CE:dbCAN_4 3.997259e-02 0.9980696
## CBM:dbCAN_4:DIAMOND-CE:dbCAN_4 6.914534e-03 0.1727470
## CE:dbCAN_4:DIAMOND-CE:dbCAN_4 5.123011e-02 1.0000000
## GH:dbCAN_4:DIAMOND-CE:dbCAN_4 7.613608e-02 1.0000000
## GT:dbCAN_4:DIAMOND-CE:dbCAN_4 7.479312e-02 1.0000000
## PL:dbCAN_4:DIAMOND-CE:dbCAN_4 9.227230e-02 1.0000000
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4 5.231854e-02 0.9999999
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4 -4.262378e-02 0.0000002
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4 6.226617e-02 1.0000000
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4 6.529990e-02 1.0000000
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4 6.612860e-02 1.0000000
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4 8.454527e-02 1.0000000
## AA:CUPP-CE:dbCAN_4 1.039533e-02 0.2375083
## CBM:CUPP-CE:dbCAN_4 -9.002495e-01 0.0000000
## CE:CUPP-CE:dbCAN_4 2.557129e-02 0.9104351
## GH:CUPP-CE:dbCAN_4 4.581259e-02 0.9999999
## GT:CUPP-CE:dbCAN_4 1.046652e-02 0.2895189
## PL:CUPP-CE:dbCAN_4 -5.163157e-03 0.0194509
## GT:dbCAN_4-GH:dbCAN_4 6.341196e-02 1.0000000
## PL:dbCAN_4-GH:dbCAN_4 7.992817e-02 1.0000000
## AA:dbCAN_4:HMMER-GH:dbCAN_4 4.880042e-02 0.9999968
## CBM:dbCAN_4:HMMER-GH:dbCAN_4 -3.089580e-01 0.0000000
## CE:dbCAN_4:HMMER-GH:dbCAN_4 4.519108e-02 0.9999998
## GH:dbCAN_4:HMMER-GH:dbCAN_4 4.729559e-02 1.0000000
## GT:dbCAN_4:HMMER-GH:dbCAN_4 1.271224e-02 0.3904513
## PL:dbCAN_4:HMMER-GH:dbCAN_4 7.992817e-02 1.0000000
## AA:dbCAN_4:DIAMOND-GH:dbCAN_4 3.599559e-02 0.9903555
## CBM:dbCAN_4:DIAMOND-GH:dbCAN_4 2.828847e-03 0.0865846
## CE:dbCAN_4:DIAMOND-GH:dbCAN_4 4.715487e-02 1.0000000
## GH:dbCAN_4:DIAMOND-GH:dbCAN_4 7.205039e-02 1.0000000
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4 7.070743e-02 1.0000000
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4 8.829994e-02 1.0000000
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4 4.834154e-02 0.9999952
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4 -4.670947e-02 0.0000000
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4 5.819093e-02 1.0000000
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4 6.121421e-02 1.0000000
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4 6.204291e-02 1.0000000
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4 8.057291e-02 1.0000000
## AA:CUPP-GH:dbCAN_4 6.418333e-03 0.1403558
## CBM:CUPP-GH:dbCAN_4 -9.043351e-01 0.0000000
## CE:CUPP-GH:dbCAN_4 2.149605e-02 0.7913051
## GH:CUPP-GH:dbCAN_4 4.172690e-02 0.9999944
## GT:CUPP-GH:dbCAN_4 6.380830e-03 0.1608074
## PL:CUPP-GH:dbCAN_4 -9.135518e-03 0.0086224
## PL:dbCAN_4-GT:dbCAN_4 7.923198e-02 1.0000000
## AA:dbCAN_4:HMMER-GT:dbCAN_4 4.810423e-02 0.9999940
## CBM:dbCAN_4:HMMER-GT:dbCAN_4 -3.096542e-01 0.0000000
## CE:dbCAN_4:HMMER-GT:dbCAN_4 4.449489e-02 0.9999995
## GH:dbCAN_4:HMMER-GT:dbCAN_4 4.659941e-02 1.0000000
## GT:dbCAN_4:HMMER-GT:dbCAN_4 1.201605e-02 0.3593560
## PL:dbCAN_4:HMMER-GT:dbCAN_4 7.923198e-02 1.0000000
## AA:dbCAN_4:DIAMOND-GT:dbCAN_4 3.529940e-02 0.9873816
## CBM:dbCAN_4:DIAMOND-GT:dbCAN_4 2.132659e-03 0.0759769
## CE:dbCAN_4:DIAMOND-GT:dbCAN_4 4.645868e-02 1.0000000
## GH:dbCAN_4:DIAMOND-GT:dbCAN_4 7.135420e-02 1.0000000
## GT:dbCAN_4:DIAMOND-GT:dbCAN_4 7.001124e-02 1.0000000
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4 8.760375e-02 1.0000000
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4 4.764535e-02 0.9999911
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4 -4.740566e-02 0.0000000
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4 5.749474e-02 1.0000000
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4 6.051802e-02 1.0000000
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4 6.134672e-02 1.0000000
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4 7.987673e-02 1.0000000
## AA:CUPP-GT:dbCAN_4 5.722144e-03 0.1266727
## CBM:CUPP-GT:dbCAN_4 -9.050313e-01 0.0000000
## CE:CUPP-GT:dbCAN_4 2.079986e-02 0.7631323
## GH:CUPP-GT:dbCAN_4 4.103072e-02 0.9999888
## GT:CUPP-GT:dbCAN_4 5.684642e-03 0.1433585
## PL:CUPP-GT:dbCAN_4 -9.831706e-03 0.0074452
## AA:dbCAN_4:HMMER-PL:dbCAN_4 5.074741e-02 0.9999355
## CBM:dbCAN_4:HMMER-PL:dbCAN_4 -3.058063e-01 0.0000000
## CE:dbCAN_4:HMMER-PL:dbCAN_4 4.822950e-02 0.9999895
## GH:dbCAN_4:HMMER-PL:dbCAN_4 5.044735e-02 0.9999991
## GT:dbCAN_4:HMMER-PL:dbCAN_4 1.586399e-02 0.4339572
## PL:dbCAN_4:HMMER-PL:dbCAN_4 8.182252e-02 1.0000000
## AA:dbCAN_4:DIAMOND-PL:dbCAN_4 3.794258e-02 0.9781203
## CBM:dbCAN_4:DIAMOND-PL:dbCAN_4 5.980603e-03 0.1308620
## CE:dbCAN_4:DIAMOND-PL:dbCAN_4 5.019330e-02 0.9999982
## GH:dbCAN_4:DIAMOND-PL:dbCAN_4 7.520215e-02 1.0000000
## GT:dbCAN_4:DIAMOND-PL:dbCAN_4 7.385919e-02 1.0000000
## PL:dbCAN_4:DIAMOND-PL:dbCAN_4 9.019429e-02 1.0000000
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4 5.028852e-02 0.9999135
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4 -4.355772e-02 0.0000010
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4 6.122936e-02 1.0000000
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4 6.436597e-02 1.0000000
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4 6.519466e-02 1.0000000
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4 8.246726e-02 1.0000000
## AA:CUPP-PL:dbCAN_4 8.365319e-03 0.1625068
## CBM:CUPP-PL:dbCAN_4 -9.011834e-01 0.0000000
## CE:CUPP-PL:dbCAN_4 2.453448e-02 0.7786514
## GH:CUPP-PL:dbCAN_4 4.487866e-02 0.9999032
## GT:CUPP-PL:dbCAN_4 9.532585e-03 0.2137671
## PL:CUPP-PL:dbCAN_4 -7.241168e-03 0.0149387
## CBM:dbCAN_4:HMMER-AA:dbCAN_4:HMMER -2.756383e-01 0.0000000
## CE:dbCAN_4:HMMER-AA:dbCAN_4:HMMER 7.840206e-02 1.0000000
## GH:dbCAN_4:HMMER-AA:dbCAN_4:HMMER 8.061527e-02 1.0000000
## GT:dbCAN_4:HMMER-AA:dbCAN_4:HMMER 4.603192e-02 0.9999667
## PL:dbCAN_4:HMMER-AA:dbCAN_4:HMMER 1.120431e-01 0.9999355
## AA:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 6.816088e-02 1.0000000
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 3.614853e-02 0.9909245
## CE:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 8.036586e-02 1.0000000
## GH:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 1.053701e-01 0.9979515
## GT:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 1.040271e-01 0.9989866
## PL:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 1.204148e-01 0.9952873
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 8.050683e-02 1.0000000
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER -1.338979e-02 0.0033575
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 9.140192e-02 1.0000000
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 9.453389e-02 0.9999993
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 9.536259e-02 0.9999983
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 1.126878e-01 0.9999028
## AA:CUPP-AA:dbCAN_4:HMMER 3.858363e-02 0.9831492
## CBM:CUPP-AA:dbCAN_4:HMMER -8.710155e-01 0.0000000
## CE:CUPP-AA:dbCAN_4:HMMER 5.470704e-02 1.0000000
## GH:CUPP-AA:dbCAN_4:HMMER 7.504658e-02 1.0000000
## GT:CUPP-AA:dbCAN_4:HMMER 3.970051e-02 0.9981804
## PL:CUPP-AA:dbCAN_4:HMMER 2.297939e-02 0.6332485
## CE:dbCAN_4:HMMER-CBM:dbCAN_4:HMMER 4.168649e-01 0.0000000
## GH:dbCAN_4:HMMER-CBM:dbCAN_4:HMMER 4.189694e-01 0.0000000
## GT:dbCAN_4:HMMER-CBM:dbCAN_4:HMMER 3.843860e-01 0.0000000
## PL:dbCAN_4:HMMER-CBM:dbCAN_4:HMMER 4.516019e-01 0.0000000
## AA:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 4.076694e-01 0.0000000
## CBM:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 3.745026e-01 0.0000000
## CE:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 4.188286e-01 0.0000000
## GH:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 4.437242e-01 0.0000000
## GT:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 4.423812e-01 0.0000000
## PL:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 4.599737e-01 0.0000000
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 4.200153e-01 0.0000000
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 3.249643e-01 0.0000000
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 4.298647e-01 0.0000000
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 4.328880e-01 0.0000000
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 4.337167e-01 0.0000000
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 4.522467e-01 0.0000000
## AA:CUPP-CBM:dbCAN_4:HMMER 3.780921e-01 0.0000000
## CBM:CUPP-CBM:dbCAN_4:HMMER -5.326614e-01 0.0000000
## CE:CUPP-CBM:dbCAN_4:HMMER 3.931698e-01 0.0000000
## GH:CUPP-CBM:dbCAN_4:HMMER 4.134007e-01 0.0000000
## GT:CUPP-CBM:dbCAN_4:HMMER 3.780546e-01 0.0000000
## PL:CUPP-CBM:dbCAN_4:HMMER 3.625383e-01 0.0000000
## GH:dbCAN_4:HMMER-CE:dbCAN_4:HMMER 6.645999e-02 1.0000000
## GT:dbCAN_4:HMMER-CE:dbCAN_4:HMMER 3.187663e-02 0.9915736
## PL:dbCAN_4:HMMER-CE:dbCAN_4:HMMER 9.897924e-02 0.9999895
## AA:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 5.505129e-02 1.0000000
## CBM:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 2.199324e-02 0.8103688
## CE:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 6.630882e-02 1.0000000
## GH:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 9.121479e-02 0.9990197
## GT:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 8.987183e-02 0.9995959
## PL:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 1.073510e-01 0.9976800
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 6.739724e-02 1.0000000
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER -2.754508e-02 0.0000345
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 7.734488e-02 1.0000000
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 8.037861e-02 1.0000000
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 8.120730e-02 0.9999999
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 9.962398e-02 0.9999822
## AA:CUPP-CE:dbCAN_4:HMMER 2.547404e-02 0.8155310
## CBM:CUPP-CE:dbCAN_4:HMMER -8.851707e-01 0.0000000
## CE:CUPP-CE:dbCAN_4:HMMER 4.065000e-02 0.9999587
## GH:CUPP-CE:dbCAN_4:HMMER 6.089130e-02 1.0000000
## GT:CUPP-CE:dbCAN_4:HMMER 2.554522e-02 0.9172928
## PL:CUPP-CE:dbCAN_4:HMMER 9.915551e-03 0.2218098
## GT:dbCAN_4:HMMER-GH:dbCAN_4:HMMER 2.813241e-02 0.9669953
## PL:dbCAN_4:HMMER-GH:dbCAN_4:HMMER 9.534835e-02 0.9999991
## AA:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 5.141577e-02 0.9999998
## CBM:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 1.824903e-02 0.6595351
## CE:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 6.257505e-02 1.0000000
## GH:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 8.747057e-02 0.9998382
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 8.612761e-02 0.9999457
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 1.037201e-01 0.9994214
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 6.376172e-02 1.0000000
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER -3.128929e-02 0.0000089
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 7.361111e-02 1.0000000
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 7.663439e-02 1.0000000
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 7.746309e-02 1.0000000
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 9.599309e-02 0.9999983
## AA:CUPP-GH:dbCAN_4:HMMER 2.183851e-02 0.6909652
## CBM:CUPP-GH:dbCAN_4:HMMER -8.889150e-01 0.0000000
## CE:CUPP-GH:dbCAN_4:HMMER 3.691623e-02 0.9995092
## GH:CUPP-GH:dbCAN_4:HMMER 5.714708e-02 1.0000000
## GT:CUPP-GH:dbCAN_4:HMMER 2.180101e-02 0.8138226
## PL:CUPP-GH:dbCAN_4:HMMER 6.284661e-03 0.1368130
## PL:dbCAN_4:HMMER-GT:dbCAN_4:HMMER 1.299317e-01 0.4339572
## AA:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 8.599912e-02 1.0000000
## CBM:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 5.283238e-02 1.0000000
## CE:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 9.715840e-02 0.9805011
## GH:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 1.220539e-01 0.0957782
## GT:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 1.207110e-01 0.1216309
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 1.383035e-01 0.1625117
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 9.834507e-02 0.9999768
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 3.294065e-03 0.0943293
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 1.081945e-01 0.6778337
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 1.112177e-01 0.4610296
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 1.120464e-01 0.4215520
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 1.305765e-01 0.4079566
## AA:CUPP-GT:dbCAN_4:HMMER 5.642187e-02 1.0000000
## CBM:CUPP-GT:dbCAN_4:HMMER -8.543316e-01 0.0000000
## CE:CUPP-GT:dbCAN_4:HMMER 7.149959e-02 1.0000000
## GH:CUPP-GT:dbCAN_4:HMMER 9.173044e-02 0.9973137
## GT:CUPP-GT:dbCAN_4:HMMER 5.638437e-02 1.0000000
## PL:CUPP-GT:dbCAN_4:HMMER 4.086802e-02 0.9988641
## AA:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 3.794258e-02 0.9781203
## CBM:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 5.980603e-03 0.1308620
## CE:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 5.019330e-02 0.9999982
## GH:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 7.520215e-02 1.0000000
## GT:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 7.385919e-02 1.0000000
## PL:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 9.019429e-02 1.0000000
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 5.028852e-02 0.9999135
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER -4.355772e-02 0.0000010
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 6.122936e-02 1.0000000
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 6.436597e-02 1.0000000
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 6.519466e-02 1.0000000
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 8.246726e-02 1.0000000
## AA:CUPP-PL:dbCAN_4:HMMER 8.365319e-03 0.1625068
## CBM:CUPP-PL:dbCAN_4:HMMER -9.011834e-01 0.0000000
## CE:CUPP-PL:dbCAN_4:HMMER 2.453448e-02 0.7786514
## GH:CUPP-PL:dbCAN_4:HMMER 4.487866e-02 0.9999032
## GT:CUPP-PL:dbCAN_4:HMMER 9.532585e-03 0.2137671
## PL:CUPP-PL:dbCAN_4:HMMER -7.241168e-03 0.0149387
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND 4.895336e-02 0.9999972
## CE:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND 9.317069e-02 0.9999999
## GH:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND 1.181749e-01 0.8587742
## GT:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND 1.168319e-01 0.8932390
## PL:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND 1.332197e-01 0.8487767
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 9.331166e-02 1.0000000
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND -5.849601e-04 0.0450938
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 1.042067e-01 0.9993664
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 1.073387e-01 0.9948413
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 1.081674e-01 0.9926553
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 1.254927e-01 0.9735451
## AA:CUPP-AA:dbCAN_4:DIAMOND 5.138846e-02 0.9999649
## CBM:CUPP-AA:dbCAN_4:DIAMOND -8.582106e-01 0.0000000
## CE:CUPP-AA:dbCAN_4:DIAMOND 6.751187e-02 1.0000000
## GH:CUPP-AA:dbCAN_4:DIAMOND 8.785142e-02 1.0000000
## GT:CUPP-AA:dbCAN_4:DIAMOND 5.250534e-02 0.9999999
## PL:CUPP-AA:dbCAN_4:DIAMOND 3.578423e-02 0.9598975
## CE:dbCAN_4:DIAMOND-CBM:dbCAN_4:DIAMOND 1.070418e-01 0.7301425
## GH:dbCAN_4:DIAMOND-CBM:dbCAN_4:DIAMOND 1.319373e-01 0.0119381
## GT:dbCAN_4:DIAMOND-CBM:dbCAN_4:DIAMOND 1.305944e-01 0.0163391
## PL:dbCAN_4:DIAMOND-CBM:dbCAN_4:DIAMOND 1.481869e-01 0.0325790
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 1.082285e-01 0.9924676
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 1.317745e-02 0.4118538
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 1.180779e-01 0.2362117
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 1.211011e-01 0.1136080
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 1.219298e-01 0.0979635
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 1.404598e-01 0.1189095
## AA:CUPP-CBM:dbCAN_4:DIAMOND 6.630526e-02 1.0000000
## CBM:CUPP-CBM:dbCAN_4:DIAMOND -8.444482e-01 0.0000000
## CE:CUPP-CBM:dbCAN_4:DIAMOND 8.138297e-02 0.9999999
## GH:CUPP-CBM:dbCAN_4:DIAMOND 1.016138e-01 0.8810617
## GT:CUPP-CBM:dbCAN_4:DIAMOND 6.626776e-02 1.0000000
## PL:CUPP-CBM:dbCAN_4:DIAMOND 5.075141e-02 0.9999993
## GH:dbCAN_4:DIAMOND-CE:dbCAN_4:DIAMOND 8.925100e-02 0.9997400
## GT:dbCAN_4:DIAMOND-CE:dbCAN_4:DIAMOND 8.790803e-02 0.9999069
## PL:dbCAN_4:DIAMOND-CE:dbCAN_4:DIAMOND 1.053872e-01 0.9991600
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 6.543345e-02 1.0000000
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND -2.950887e-02 0.0000183
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 7.538108e-02 1.0000000
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 7.841481e-02 1.0000000
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 7.924351e-02 1.0000000
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 9.766019e-02 0.9999967
## AA:CUPP-CE:dbCAN_4:DIAMOND 2.351025e-02 0.7473475
## CBM:CUPP-CE:dbCAN_4:DIAMOND -8.871345e-01 0.0000000
## CE:CUPP-CE:dbCAN_4:DIAMOND 3.868621e-02 0.9998034
## GH:CUPP-CE:dbCAN_4:DIAMOND 5.892751e-02 1.0000000
## GT:CUPP-CE:dbCAN_4:DIAMOND 2.358143e-02 0.8647488
## PL:CUPP-CE:dbCAN_4:DIAMOND 7.951759e-03 0.1713754
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND 6.137281e-02 1.0000000
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND 7.896532e-02 1.0000000
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 3.900692e-02 0.9974311
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND -5.604409e-02 0.0000000
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 4.885631e-02 1.0000000
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 5.187959e-02 1.0000000
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 5.270829e-02 1.0000000
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 7.123829e-02 1.0000000
## AA:CUPP-GH:dbCAN_4:DIAMOND -2.916288e-03 0.0294550
## CBM:CUPP-GH:dbCAN_4:DIAMOND -9.136698e-01 0.0000000
## CE:CUPP-GH:dbCAN_4:DIAMOND 1.216143e-02 0.3588504
## GH:CUPP-GH:dbCAN_4:DIAMOND 3.239228e-02 0.9946255
## GT:CUPP-GH:dbCAN_4:DIAMOND -2.953790e-03 0.0268341
## PL:CUPP-GH:dbCAN_4:DIAMOND -1.847014e-02 0.0010511
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4:DIAMOND 8.030828e-02 1.0000000
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 4.034988e-02 0.9987019
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND -5.470113e-02 0.0000000
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 5.019927e-02 1.0000000
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 5.322255e-02 1.0000000
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 5.405125e-02 1.0000000
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 7.258126e-02 1.0000000
## AA:CUPP-GT:dbCAN_4:DIAMOND -1.573326e-03 0.0377486
## CBM:CUPP-GT:dbCAN_4:DIAMOND -9.123268e-01 0.0000000
## CE:CUPP-GT:dbCAN_4:DIAMOND 1.350439e-02 0.4189764
## GH:CUPP-GT:dbCAN_4:DIAMOND 3.373524e-02 0.9973644
## GT:CUPP-GT:dbCAN_4:DIAMOND -1.610829e-03 0.0358237
## PL:CUPP-GT:dbCAN_4:DIAMOND -1.712718e-02 0.0014479
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 4.191675e-02 0.9943632
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -5.192949e-02 0.0000001
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 5.285759e-02 0.9999999
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 5.599420e-02 1.0000000
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 5.682289e-02 1.0000000
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 7.409549e-02 1.0000000
## AA:CUPP-PL:dbCAN_4:DIAMOND -6.450644e-06 0.0499497
## CBM:CUPP-PL:dbCAN_4:DIAMOND -9.095552e-01 0.0000000
## CE:CUPP-PL:dbCAN_4:DIAMOND 1.616271e-02 0.4398246
## GH:CUPP-PL:dbCAN_4:DIAMOND 3.650689e-02 0.9913444
## GT:CUPP-PL:dbCAN_4:DIAMOND 1.160815e-03 0.0610254
## PL:CUPP-PL:dbCAN_4:DIAMOND -1.561294e-02 0.0030465
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub -1.293091e-02 0.0037232
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub 9.186080e-02 1.0000000
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub 9.499277e-02 0.9999988
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub 9.582147e-02 0.9999974
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub 1.131467e-01 0.9998710
## AA:CUPP-AA:dbCAN_4:dbCAN-sub 3.904251e-02 0.9854736
## CBM:CUPP-AA:dbCAN_4:dbCAN-sub -8.705566e-01 0.0000000
## CE:CUPP-AA:dbCAN_4:dbCAN-sub 5.516592e-02 1.0000000
## GH:CUPP-AA:dbCAN_4:dbCAN-sub 7.550547e-02 1.0000000
## GT:CUPP-AA:dbCAN_4:dbCAN-sub 4.015939e-02 0.9985645
## PL:CUPP-AA:dbCAN_4:dbCAN-sub 2.343828e-02 0.6504088
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:dbCAN-sub 1.676162e-01 0.0000004
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:dbCAN-sub 1.706395e-01 0.0000001
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:dbCAN-sub 1.714682e-01 0.0000000
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:dbCAN-sub 1.899982e-01 0.0000008
## AA:CUPP-CBM:dbCAN_4:dbCAN-sub 1.158436e-01 0.9148083
## CBM:CUPP-CBM:dbCAN_4:dbCAN-sub -7.949099e-01 0.0000000
## CE:CUPP-CBM:dbCAN_4:dbCAN-sub 1.309213e-01 0.0222548
## GH:CUPP-CBM:dbCAN_4:dbCAN-sub 1.511521e-01 0.0000554
## GT:CUPP-CBM:dbCAN_4:dbCAN-sub 1.158061e-01 0.2627895
## PL:CUPP-CBM:dbCAN_4:dbCAN-sub 1.002897e-01 0.9999381
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4:dbCAN-sub 6.737875e-02 1.0000000
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4:dbCAN-sub 6.820745e-02 1.0000000
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4:dbCAN-sub 8.662413e-02 1.0000000
## AA:CUPP-CE:dbCAN_4:dbCAN-sub 1.247419e-02 0.3040052
## CBM:CUPP-CE:dbCAN_4:dbCAN-sub -8.981706e-01 0.0000000
## CE:CUPP-CE:dbCAN_4:dbCAN-sub 2.765015e-02 0.9507412
## GH:CUPP-CE:dbCAN_4:dbCAN-sub 4.789145e-02 1.0000000
## GT:CUPP-CE:dbCAN_4:dbCAN-sub 1.254537e-02 0.3756210
## PL:CUPP-CE:dbCAN_4:dbCAN-sub -3.084301e-03 0.0288081
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub 6.354447e-02 1.0000000
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub 8.207448e-02 1.0000000
## AA:CUPP-GH:dbCAN_4:dbCAN-sub 7.919895e-03 0.1736731
## CBM:CUPP-GH:dbCAN_4:dbCAN-sub -9.028336e-01 0.0000000
## CE:CUPP-GH:dbCAN_4:dbCAN-sub 2.299761e-02 0.8459585
## GH:CUPP-GH:dbCAN_4:dbCAN-sub 4.322847e-02 0.9999989
## GT:CUPP-GH:dbCAN_4:dbCAN-sub 7.882392e-03 0.2037115
## PL:CUPP-GH:dbCAN_4:dbCAN-sub -7.633956e-03 0.0117641
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:dbCAN-sub 8.124578e-02 1.0000000
## AA:CUPP-GT:dbCAN_4:dbCAN-sub 7.091197e-03 0.1546296
## CBM:CUPP-GT:dbCAN_4:dbCAN-sub -9.036623e-01 0.0000000
## CE:CUPP-GT:dbCAN_4:dbCAN-sub 2.216891e-02 0.8168817
## GH:CUPP-GT:dbCAN_4:dbCAN-sub 4.239977e-02 0.9999973
## GT:CUPP-GT:dbCAN_4:dbCAN-sub 7.053694e-03 0.1791286
## PL:CUPP-GT:dbCAN_4:dbCAN-sub -8.462653e-03 0.0099204
## AA:CUPP-PL:dbCAN_4:dbCAN-sub 7.720574e-03 0.1498010
## CBM:CUPP-PL:dbCAN_4:dbCAN-sub -9.018281e-01 0.0000000
## CE:CUPP-PL:dbCAN_4:dbCAN-sub 2.388973e-02 0.7556647
## GH:CUPP-PL:dbCAN_4:dbCAN-sub 4.423391e-02 0.9998496
## GT:CUPP-PL:dbCAN_4:dbCAN-sub 8.887840e-03 0.1964824
## PL:CUPP-PL:dbCAN_4:dbCAN-sub -7.885914e-03 0.0133106
## CBM:CUPP-AA:CUPP -8.286334e-01 0.0000000
## CE:CUPP-AA:CUPP 9.708913e-02 0.9999965
## GH:CUPP-AA:CUPP 1.174287e-01 0.8786585
## GT:CUPP-AA:CUPP 8.208260e-02 1.0000000
## PL:CUPP-AA:CUPP 6.536148e-02 1.0000000
## CE:CUPP-CBM:CUPP 9.885470e-01 0.0000000
## GH:CUPP-CBM:CUPP 1.008778e+00 0.0000000
## GT:CUPP-CBM:CUPP 9.734317e-01 0.0000000
## PL:CUPP-CBM:CUPP 9.579154e-01 0.0000000
## GH:CUPP-CE:CUPP 8.458633e-02 0.9999955
## GT:CUPP-CE:CUPP 4.924025e-02 1.0000000
## PL:CUPP-CE:CUPP 3.361058e-02 0.9725413
## GT:CUPP-GH:CUPP 2.736970e-02 0.9570711
## PL:CUPP-GH:CUPP 1.185335e-02 0.2843350
## PL:CUPP-GT:CUPP 4.719942e-02 0.99998326.5.5 CAZy class accuracy
Two-way ANOVA to test for differences between the CAZy classes and prediction tools.
## Df Sum Sq Mean Sq F value Pr(>F)
## CAZy_class 5 0.5235 0.10469 80.70 <2e-16 ***
## Prediction_tool 4 0.3188 0.07971 61.44 <2e-16 ***
## CAZy_class:Prediction_tool 20 0.3562 0.01781 13.73 <2e-16 ***
## Residuals 2025 2.6271 0.00130
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1Statistically significant difference was detected, so follow up with a Tukey test to determine if there are differences between specific groups.
## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistic_value ~ CAZy_class * Prediction_tool, data = class_subset_acc.df)
##
## $`CAZy_class:Prediction_tool`
## diff lwr
## CBM:dbCAN_4-AA:dbCAN_4 -1.441409e-02 -0.0391014082
## CE:dbCAN_4-AA:dbCAN_4 3.591690e-03 -0.0213380595
## GH:dbCAN_4-AA:dbCAN_4 -1.637808e-02 -0.0410653953
## GT:dbCAN_4-AA:dbCAN_4 -1.259177e-02 -0.0372790867
## PL:dbCAN_4-AA:dbCAN_4 7.841092e-03 -0.0199065921
## AA:dbCAN_4:HMMER-AA:dbCAN_4 -6.237616e-04 -0.0282250194
## CBM:dbCAN_4:HMMER-AA:dbCAN_4 -4.708476e-02 -0.0717720792
## CE:dbCAN_4:HMMER-AA:dbCAN_4 2.143338e-03 -0.0227864117
## GH:dbCAN_4:HMMER-AA:dbCAN_4 -3.059767e-02 -0.0552849879
## GT:dbCAN_4:HMMER-AA:dbCAN_4 -4.046118e-02 -0.0651484912
## PL:dbCAN_4:HMMER-AA:dbCAN_4 7.835740e-03 -0.0199119446
## AA:dbCAN_4:DIAMOND-AA:dbCAN_4 -1.014308e-03 -0.0286155657
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4 -7.729333e-03 -0.0324166485
## CE:dbCAN_4:DIAMOND-AA:dbCAN_4 1.223836e-03 -0.0237059143
## GH:dbCAN_4:DIAMOND-AA:dbCAN_4 -9.483024e-03 -0.0341703391
## GT:dbCAN_4:DIAMOND-AA:dbCAN_4 -6.928474e-03 -0.0316157893
## PL:dbCAN_4:DIAMOND-AA:dbCAN_4 8.028418e-03 -0.0197192670
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4 -5.699252e-04 -0.0281711829
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4 -1.457496e-02 -0.0392622794
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4 3.095406e-03 -0.0218343442
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4 -1.758755e-02 -0.0422748648
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4 -1.342538e-02 -0.0381126995
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4 8.057165e-03 -0.0196905195
## AA:CUPP-AA:dbCAN_4 -6.645453e-03 -0.0342467104
## CBM:CUPP-AA:dbCAN_4 -1.056142e-01 -0.1303015254
## CE:CUPP-AA:dbCAN_4 -7.125649e-04 -0.0256423148
## GH:CUPP-AA:dbCAN_4 -3.672975e-02 -0.0614170616
## GT:CUPP-AA:dbCAN_4 -4.452252e-02 -0.0692098314
## PL:CUPP-AA:dbCAN_4 3.425628e-03 -0.0243220562
## CE:dbCAN_4-CBM:dbCAN_4 1.800578e-02 -0.0036535461
## GH:dbCAN_4-CBM:dbCAN_4 -1.963987e-03 -0.0233438294
## GT:dbCAN_4-CBM:dbCAN_4 1.822322e-03 -0.0195575208
## PL:dbCAN_4-CBM:dbCAN_4 2.225519e-02 -0.0025957325
## AA:dbCAN_4:HMMER-CBM:dbCAN_4 1.379033e-02 -0.0108969843
## CBM:dbCAN_4:HMMER-CBM:dbCAN_4 -3.267067e-02 -0.0540505133
## CE:dbCAN_4:HMMER-CBM:dbCAN_4 1.655743e-02 -0.0051018983
## GH:dbCAN_4:HMMER-CBM:dbCAN_4 -1.618358e-02 -0.0375634220
## GT:dbCAN_4:HMMER-CBM:dbCAN_4 -2.604708e-02 -0.0474269254
## PL:dbCAN_4:HMMER-CBM:dbCAN_4 2.224983e-02 -0.0026010850
## AA:dbCAN_4:DIAMOND-CBM:dbCAN_4 1.339978e-02 -0.0112875306
## CBM:dbCAN_4:DIAMOND-CBM:dbCAN_4 6.684760e-03 -0.0146950826
## CE:dbCAN_4:DIAMOND-CBM:dbCAN_4 1.563793e-02 -0.0060214009
## GH:dbCAN_4:DIAMOND-CBM:dbCAN_4 4.931069e-03 -0.0164487732
## GT:dbCAN_4:DIAMOND-CBM:dbCAN_4 7.485619e-03 -0.0138942234
## PL:dbCAN_4:DIAMOND-CBM:dbCAN_4 2.244251e-02 -0.0024084074
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 1.384417e-02 -0.0108431478
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 -1.608712e-04 -0.0215407135
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 1.750950e-02 -0.0041498308
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 -3.173457e-03 -0.0245532989
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 9.887087e-04 -0.0203911336
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 2.247126e-02 -0.0023796599
## AA:CUPP-CBM:dbCAN_4 7.768640e-03 -0.0169186753
## CBM:CUPP-CBM:dbCAN_4 -9.120012e-02 -0.1125799595
## CE:CUPP-CBM:dbCAN_4 1.370153e-02 -0.0079578014
## GH:CUPP-CBM:dbCAN_4 -2.231565e-02 -0.0436954957
## GT:CUPP-CBM:dbCAN_4 -3.010842e-02 -0.0514882655
## PL:CUPP-CBM:dbCAN_4 1.783972e-02 -0.0070111966
## GH:dbCAN_4-CE:dbCAN_4 -1.996977e-02 -0.0416290995
## GT:dbCAN_4-CE:dbCAN_4 -1.618346e-02 -0.0378427909
## PL:dbCAN_4-CE:dbCAN_4 4.249402e-03 -0.0208423695
## AA:dbCAN_4:HMMER-CE:dbCAN_4 -4.215452e-03 -0.0291452019
## CBM:dbCAN_4:HMMER-CE:dbCAN_4 -5.067645e-02 -0.0723357834
## CE:dbCAN_4:HMMER-CE:dbCAN_4 -1.448352e-03 -0.0233836076
## GH:dbCAN_4:HMMER-CE:dbCAN_4 -3.418936e-02 -0.0558486921
## GT:dbCAN_4:HMMER-CE:dbCAN_4 -4.405287e-02 -0.0657121954
## PL:dbCAN_4:HMMER-CE:dbCAN_4 4.244050e-03 -0.0208477220
## AA:dbCAN_4:DIAMOND-CE:dbCAN_4 -4.605998e-03 -0.0295357483
## CBM:dbCAN_4:DIAMOND-CE:dbCAN_4 -1.132102e-02 -0.0329803527
## CE:dbCAN_4:DIAMOND-CE:dbCAN_4 -2.367855e-03 -0.0243031103
## GH:dbCAN_4:DIAMOND-CE:dbCAN_4 -1.307471e-02 -0.0347340433
## GT:dbCAN_4:DIAMOND-CE:dbCAN_4 -1.052016e-02 -0.0321794935
## PL:dbCAN_4:DIAMOND-CE:dbCAN_4 4.436727e-03 -0.0206550443
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4 -4.161616e-03 -0.0290913654
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4 -1.816665e-02 -0.0398259836
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4 -4.962847e-04 -0.0224315401
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4 -2.117924e-02 -0.0428385690
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4 -1.701707e-02 -0.0386764037
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4 4.465475e-03 -0.0206262969
## AA:CUPP-CE:dbCAN_4 -1.023714e-02 -0.0351668929
## CBM:CUPP-CE:dbCAN_4 -1.092059e-01 -0.1308652296
## CE:CUPP-CE:dbCAN_4 -4.304255e-03 -0.0262395107
## GH:CUPP-CE:dbCAN_4 -4.032144e-02 -0.0619807658
## GT:CUPP-CE:dbCAN_4 -4.811421e-02 -0.0697735356
## PL:CUPP-CE:dbCAN_4 -1.660621e-04 -0.0252578336
## GT:dbCAN_4-GH:dbCAN_4 3.786309e-03 -0.0175935337
## PL:dbCAN_4-GH:dbCAN_4 2.421917e-02 -0.0006317454
## AA:dbCAN_4:HMMER-GH:dbCAN_4 1.575432e-02 -0.0089329972
## CBM:dbCAN_4:HMMER-GH:dbCAN_4 -3.070668e-02 -0.0520865262
## CE:dbCAN_4:HMMER-GH:dbCAN_4 1.852142e-02 -0.0031379112
## GH:dbCAN_4:HMMER-GH:dbCAN_4 -1.421959e-02 -0.0355994349
## GT:dbCAN_4:HMMER-GH:dbCAN_4 -2.408310e-02 -0.0454629382
## PL:dbCAN_4:HMMER-GH:dbCAN_4 2.421382e-02 -0.0006370979
## AA:dbCAN_4:DIAMOND-GH:dbCAN_4 1.536377e-02 -0.0093235435
## CBM:dbCAN_4:DIAMOND-GH:dbCAN_4 8.648747e-03 -0.0127310955
## CE:dbCAN_4:DIAMOND-GH:dbCAN_4 1.760192e-02 -0.0040574138
## GH:dbCAN_4:DIAMOND-GH:dbCAN_4 6.895056e-03 -0.0144847861
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4 9.449606e-03 -0.0119302363
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4 2.440650e-02 -0.0004444203
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4 1.580815e-02 -0.0088791607
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4 1.803116e-03 -0.0195767264
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4 1.947349e-02 -0.0021858437
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4 -1.209470e-03 -0.0225893118
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4 2.952696e-03 -0.0184271465
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4 2.443524e-02 -0.0004156728
## AA:CUPP-GH:dbCAN_4 9.732627e-03 -0.0149546882
## CBM:CUPP-GH:dbCAN_4 -8.923613e-02 -0.1106159724
## CE:CUPP-GH:dbCAN_4 1.566551e-02 -0.0059938143
## GH:CUPP-GH:dbCAN_4 -2.035167e-02 -0.0417315086
## GT:CUPP-GH:dbCAN_4 -2.814444e-02 -0.0495242784
## PL:CUPP-GH:dbCAN_4 1.980371e-02 -0.0050472095
## PL:dbCAN_4-GT:dbCAN_4 2.043286e-02 -0.0044180541
## AA:dbCAN_4:HMMER-GT:dbCAN_4 1.196801e-02 -0.0127193058
## CBM:dbCAN_4:HMMER-GT:dbCAN_4 -3.449299e-02 -0.0558728348
## CE:dbCAN_4:HMMER-GT:dbCAN_4 1.473511e-02 -0.0069242198
## GH:dbCAN_4:HMMER-GT:dbCAN_4 -1.800590e-02 -0.0393857436
## GT:dbCAN_4:HMMER-GT:dbCAN_4 -2.786940e-02 -0.0492492469
## PL:dbCAN_4:HMMER-GT:dbCAN_4 2.042751e-02 -0.0044234066
## AA:dbCAN_4:DIAMOND-GT:dbCAN_4 1.157746e-02 -0.0131098522
## CBM:dbCAN_4:DIAMOND-GT:dbCAN_4 4.862438e-03 -0.0165174042
## CE:dbCAN_4:DIAMOND-GT:dbCAN_4 1.381561e-02 -0.0078437225
## GH:dbCAN_4:DIAMOND-GT:dbCAN_4 3.108748e-03 -0.0182710948
## GT:dbCAN_4:DIAMOND-GT:dbCAN_4 5.663297e-03 -0.0157165449
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4 2.062019e-02 -0.0042307289
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4 1.202185e-02 -0.0126654694
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4 -1.983193e-03 -0.0233630351
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4 1.568718e-02 -0.0059721524
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4 -4.995778e-03 -0.0263756205
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4 -8.336128e-04 -0.0222134551
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4 2.064894e-02 -0.0042019814
## AA:CUPP-GT:dbCAN_4 5.946319e-03 -0.0187409969
## CBM:CUPP-GT:dbCAN_4 -9.302244e-02 -0.1144022811
## CE:CUPP-GT:dbCAN_4 1.187921e-02 -0.0097801229
## GH:CUPP-GT:dbCAN_4 -2.413797e-02 -0.0455178172
## GT:CUPP-GT:dbCAN_4 -3.193074e-02 -0.0533105871
## PL:CUPP-GT:dbCAN_4 1.601740e-02 -0.0088335182
## AA:dbCAN_4:HMMER-PL:dbCAN_4 -8.464854e-03 -0.0362125386
## CBM:dbCAN_4:HMMER-PL:dbCAN_4 -5.492586e-02 -0.0797767739
## CE:dbCAN_4:HMMER-PL:dbCAN_4 -5.697754e-03 -0.0307895258
## GH:dbCAN_4:HMMER-PL:dbCAN_4 -3.843876e-02 -0.0632896826
## GT:dbCAN_4:HMMER-PL:dbCAN_4 -4.830227e-02 -0.0731531860
## PL:dbCAN_4:HMMER-PL:dbCAN_4 -5.352518e-06 -0.0278986952
## AA:dbCAN_4:DIAMOND-PL:dbCAN_4 -8.855400e-03 -0.0366030850
## CBM:dbCAN_4:DIAMOND-PL:dbCAN_4 -1.557043e-02 -0.0404213433
## CE:dbCAN_4:DIAMOND-PL:dbCAN_4 -6.617257e-03 -0.0317090284
## GH:dbCAN_4:DIAMOND-PL:dbCAN_4 -1.732412e-02 -0.0421750338
## GT:dbCAN_4:DIAMOND-PL:dbCAN_4 -1.476957e-02 -0.0396204840
## PL:dbCAN_4:DIAMOND-PL:dbCAN_4 1.873251e-04 -0.0277060176
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4 -8.411018e-03 -0.0361587021
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4 -2.241606e-02 -0.0472669742
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4 -4.745687e-03 -0.0298374583
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4 -2.542864e-02 -0.0502795596
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4 -2.126648e-02 -0.0461173942
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4 2.160726e-04 -0.0276772701
## AA:CUPP-PL:dbCAN_4 -1.448655e-02 -0.0422342297
## CBM:CUPP-PL:dbCAN_4 -1.134553e-01 -0.1383062201
## CE:CUPP-PL:dbCAN_4 -8.553657e-03 -0.0336454289
## GH:CUPP-PL:dbCAN_4 -4.457084e-02 -0.0694217563
## GT:CUPP-PL:dbCAN_4 -5.236361e-02 -0.0772145261
## PL:CUPP-PL:dbCAN_4 -4.415464e-03 -0.0323088068
## CBM:dbCAN_4:HMMER-AA:dbCAN_4:HMMER -4.646100e-02 -0.0711483175
## CE:dbCAN_4:HMMER-AA:dbCAN_4:HMMER 2.767100e-03 -0.0221626501
## GH:dbCAN_4:HMMER-AA:dbCAN_4:HMMER -2.997391e-02 -0.0546612263
## GT:dbCAN_4:HMMER-AA:dbCAN_4:HMMER -3.983741e-02 -0.0645247296
## PL:dbCAN_4:HMMER-AA:dbCAN_4:HMMER 8.459502e-03 -0.0192881830
## AA:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER -3.905463e-04 -0.0279918041
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER -7.105571e-03 -0.0317928869
## CE:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 1.847597e-03 -0.0230821527
## GH:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER -8.859262e-03 -0.0335465775
## GT:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER -6.304712e-03 -0.0309920277
## PL:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 8.652179e-03 -0.0190955053
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 5.383648e-05 -0.0275474213
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER -1.395120e-02 -0.0386385178
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 3.719167e-03 -0.0212105826
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER -1.696379e-02 -0.0416511032
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER -1.280162e-02 -0.0374889378
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 8.680927e-03 -0.0190667579
## AA:CUPP-AA:dbCAN_4:HMMER -6.021691e-03 -0.0336229488
## CBM:CUPP-AA:dbCAN_4:HMMER -1.049904e-01 -0.1296777638
## CE:CUPP-AA:dbCAN_4:HMMER -8.880327e-05 -0.0250185532
## GH:CUPP-AA:dbCAN_4:HMMER -3.610598e-02 -0.0607932999
## GT:CUPP-AA:dbCAN_4:HMMER -4.389875e-02 -0.0685860698
## PL:CUPP-AA:dbCAN_4:HMMER 4.049390e-03 -0.0236982946
## CE:dbCAN_4:HMMER-CBM:dbCAN_4:HMMER 4.922810e-02 0.0275687727
## GH:dbCAN_4:HMMER-CBM:dbCAN_4:HMMER 1.648709e-02 -0.0048927511
## GT:dbCAN_4:HMMER-CBM:dbCAN_4:HMMER 6.623588e-03 -0.0147562544
## PL:dbCAN_4:HMMER-CBM:dbCAN_4:HMMER 5.492050e-02 0.0300695859
## AA:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 4.607046e-02 0.0213831403
## CBM:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 3.935543e-02 0.0179755883
## CE:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 4.830860e-02 0.0266492700
## GH:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 3.760174e-02 0.0162218977
## GT:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 4.015629e-02 0.0187764476
## PL:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 5.511318e-02 0.0302622636
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 4.651484e-02 0.0218275231
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 3.250980e-02 0.0111299574
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 5.018017e-02 0.0285208401
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 2.949721e-02 0.0081173720
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 3.365938e-02 0.0122795374
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 5.514193e-02 0.0302910111
## AA:CUPP-CBM:dbCAN_4:HMMER 4.043931e-02 0.0157519956
## CBM:CUPP-CBM:dbCAN_4:HMMER -5.852945e-02 -0.0799092886
## CE:CUPP-CBM:dbCAN_4:HMMER 4.637220e-02 0.0247128696
## GH:CUPP-CBM:dbCAN_4:HMMER 1.035502e-02 -0.0110248247
## GT:CUPP-CBM:dbCAN_4:HMMER 2.562248e-03 -0.0188175946
## PL:CUPP-CBM:dbCAN_4:HMMER 5.051039e-02 0.0256594743
## GH:dbCAN_4:HMMER-CE:dbCAN_4:HMMER -3.274101e-02 -0.0544003399
## GT:dbCAN_4:HMMER-CE:dbCAN_4:HMMER -4.260451e-02 -0.0642638432
## PL:dbCAN_4:HMMER-CE:dbCAN_4:HMMER 5.692402e-03 -0.0193993698
## AA:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER -3.157646e-03 -0.0280873960
## CBM:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER -9.872671e-03 -0.0315320005
## CE:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER -9.195026e-04 -0.0228547580
## GH:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER -1.162636e-02 -0.0332856911
## GT:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER -9.071812e-03 -0.0307311413
## PL:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 5.885079e-03 -0.0192066921
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER -2.713263e-03 -0.0276430132
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER -1.671830e-02 -0.0383776314
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 9.520675e-04 -0.0209831879
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER -1.973089e-02 -0.0413902168
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER -1.556872e-02 -0.0372280515
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 5.913827e-03 -0.0191779447
## AA:CUPP-CE:dbCAN_4:HMMER -8.788791e-03 -0.0337185407
## CBM:CUPP-CE:dbCAN_4:HMMER -1.077575e-01 -0.1294168774
## CE:CUPP-CE:dbCAN_4:HMMER -2.855903e-03 -0.0247911585
## GH:CUPP-CE:dbCAN_4:HMMER -3.887308e-02 -0.0605324136
## GT:CUPP-CE:dbCAN_4:HMMER -4.666585e-02 -0.0683251834
## PL:CUPP-CE:dbCAN_4:HMMER 1.282290e-03 -0.0238094814
## GT:dbCAN_4:HMMER-GH:dbCAN_4:HMMER -9.863503e-03 -0.0312433456
## PL:dbCAN_4:HMMER-GH:dbCAN_4:HMMER 3.843341e-02 0.0135824947
## AA:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 2.958336e-02 0.0048960491
## CBM:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 2.286834e-02 0.0014884971
## CE:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 3.182151e-02 0.0101621788
## GH:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 2.111465e-02 -0.0002651935
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 2.366920e-02 0.0022893563
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 3.862609e-02 0.0137751723
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 3.002775e-02 0.0053404319
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 1.602271e-02 -0.0053571338
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 3.369308e-02 0.0120337489
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 1.301012e-02 -0.0083697192
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 1.717229e-02 -0.0042075539
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 3.865484e-02 0.0138039198
## AA:CUPP-GH:dbCAN_4:HMMER 2.395222e-02 -0.0007350956
## CBM:CUPP-GH:dbCAN_4:HMMER -7.501654e-02 -0.0963963798
## CE:CUPP-GH:dbCAN_4:HMMER 2.988511e-02 0.0082257783
## GH:CUPP-GH:dbCAN_4:HMMER -6.132074e-03 -0.0275119160
## GT:CUPP-GH:dbCAN_4:HMMER -1.392484e-02 -0.0353046858
## PL:CUPP-GH:dbCAN_4:HMMER 3.402330e-02 0.0091723831
## PL:dbCAN_4:HMMER-GT:dbCAN_4:HMMER 4.829692e-02 0.0234459980
## AA:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 3.944687e-02 0.0147595524
## CBM:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 3.273184e-02 0.0113520004
## CE:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 4.168501e-02 0.0200256821
## GH:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 3.097815e-02 0.0095983098
## GT:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 3.353270e-02 0.0121528596
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 4.848959e-02 0.0236386756
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 3.989125e-02 0.0152039352
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 2.588621e-02 0.0045063695
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 4.355658e-02 0.0218972522
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 2.287363e-02 0.0014937841
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 2.703579e-02 0.0056559494
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 4.851834e-02 0.0236674231
## AA:CUPP-GT:dbCAN_4:HMMER 3.381572e-02 0.0091284077
## CBM:CUPP-GT:dbCAN_4:HMMER -6.515303e-02 -0.0865328765
## CE:CUPP-GT:dbCAN_4:HMMER 3.974861e-02 0.0180892816
## GH:CUPP-GT:dbCAN_4:HMMER 3.731430e-03 -0.0176484126
## GT:CUPP-GT:dbCAN_4:HMMER -4.061340e-03 -0.0254411825
## PL:CUPP-GT:dbCAN_4:HMMER 4.388680e-02 0.0190358864
## AA:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER -8.850048e-03 -0.0365977325
## CBM:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER -1.556507e-02 -0.0404159907
## CE:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER -6.611904e-03 -0.0317036759
## GH:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER -1.731876e-02 -0.0421696813
## GT:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER -1.476421e-02 -0.0396151315
## PL:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 1.926777e-04 -0.0277006650
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER -8.405665e-03 -0.0361533496
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER -2.241070e-02 -0.0472616216
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER -4.740334e-03 -0.0298321058
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER -2.542329e-02 -0.0502742070
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER -2.126112e-02 -0.0461120417
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 2.214251e-04 -0.0276719176
## AA:CUPP-PL:dbCAN_4:HMMER -1.448119e-02 -0.0422288771
## CBM:CUPP-PL:dbCAN_4:HMMER -1.134499e-01 -0.1383008676
## CE:CUPP-PL:dbCAN_4:HMMER -8.548305e-03 -0.0336400764
## GH:CUPP-PL:dbCAN_4:HMMER -4.456549e-02 -0.0694164038
## GT:CUPP-PL:dbCAN_4:HMMER -5.235826e-02 -0.0772091736
## PL:CUPP-PL:dbCAN_4:HMMER -4.410112e-03 -0.0323034543
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND -6.715025e-03 -0.0314023405
## CE:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND 2.238144e-03 -0.0226916064
## GH:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND -8.468716e-03 -0.0331560311
## GT:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND -5.914166e-03 -0.0306014813
## PL:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND 9.042726e-03 -0.0187049590
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 4.443828e-04 -0.0271568749
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND -1.356066e-02 -0.0382479714
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 4.109714e-03 -0.0208200363
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND -1.657324e-02 -0.0412605569
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND -1.241108e-02 -0.0370983915
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 9.071473e-03 -0.0186762115
## AA:CUPP-AA:dbCAN_4:DIAMOND -5.631145e-03 -0.0332324024
## CBM:CUPP-AA:dbCAN_4:DIAMOND -1.045999e-01 -0.1292872174
## CE:CUPP-AA:dbCAN_4:DIAMOND 3.017431e-04 -0.0246280068
## GH:CUPP-AA:dbCAN_4:DIAMOND -3.571544e-02 -0.0604027536
## GT:CUPP-AA:dbCAN_4:DIAMOND -4.350821e-02 -0.0681955234
## PL:CUPP-AA:dbCAN_4:DIAMOND 4.439936e-03 -0.0233077482
## CE:dbCAN_4:DIAMOND-CBM:dbCAN_4:DIAMOND 8.953169e-03 -0.0127061606
## GH:dbCAN_4:DIAMOND-CBM:dbCAN_4:DIAMOND -1.753691e-03 -0.0231335329
## GT:dbCAN_4:DIAMOND-CBM:dbCAN_4:DIAMOND 8.008592e-04 -0.0205789831
## PL:dbCAN_4:DIAMOND-CBM:dbCAN_4:DIAMOND 1.575775e-02 -0.0090931671
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 7.159408e-03 -0.0175279075
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND -6.845631e-03 -0.0282254732
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 1.082474e-02 -0.0108345905
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND -9.858216e-03 -0.0312380586
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND -5.696051e-03 -0.0270758933
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 1.578650e-02 -0.0090644196
## AA:CUPP-CBM:dbCAN_4:DIAMOND 1.083880e-03 -0.0236034350
## CBM:CUPP-CBM:dbCAN_4:DIAMOND -9.788488e-02 -0.1192647192
## CE:CUPP-CBM:dbCAN_4:DIAMOND 7.016768e-03 -0.0146425611
## GH:CUPP-CBM:dbCAN_4:DIAMOND -2.900041e-02 -0.0503802554
## GT:CUPP-CBM:dbCAN_4:DIAMOND -3.679318e-02 -0.0581730252
## PL:CUPP-CBM:dbCAN_4:DIAMOND 1.115496e-02 -0.0136959563
## GH:dbCAN_4:DIAMOND-CE:dbCAN_4:DIAMOND -1.070686e-02 -0.0323661885
## GT:dbCAN_4:DIAMOND-CE:dbCAN_4:DIAMOND -8.152309e-03 -0.0298116386
## PL:dbCAN_4:DIAMOND-CE:dbCAN_4:DIAMOND 6.804582e-03 -0.0182871895
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND -1.793761e-03 -0.0267235106
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND -1.579880e-02 -0.0374581288
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 1.871570e-03 -0.0200636853
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND -1.881138e-02 -0.0404707142
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND -1.464922e-02 -0.0363085488
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 6.833330e-03 -0.0182584420
## AA:CUPP-CE:dbCAN_4:DIAMOND -7.869288e-03 -0.0327990381
## CBM:CUPP-CE:dbCAN_4:DIAMOND -1.068380e-01 -0.1284973748
## CE:CUPP-CE:dbCAN_4:DIAMOND -1.936400e-03 -0.0238716558
## GH:CUPP-CE:dbCAN_4:DIAMOND -3.795358e-02 -0.0596129109
## GT:CUPP-CE:dbCAN_4:DIAMOND -4.574635e-02 -0.0674056808
## PL:CUPP-CE:dbCAN_4:DIAMOND 2.201793e-03 -0.0228899787
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND 2.554550e-03 -0.0188252925
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND 1.751144e-02 -0.0073394765
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 8.913099e-03 -0.0157742169
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND -5.091940e-03 -0.0264717826
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 1.257843e-02 -0.0090808999
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND -8.104526e-03 -0.0294843680
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND -3.942360e-03 -0.0253222027
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 1.754019e-02 -0.0073107290
## AA:CUPP-GH:dbCAN_4:DIAMOND 2.837571e-03 -0.0218497444
## CBM:CUPP-GH:dbCAN_4:DIAMOND -9.613119e-02 -0.1175110286
## CE:CUPP-GH:dbCAN_4:DIAMOND 8.770459e-03 -0.0128888705
## GH:CUPP-GH:dbCAN_4:DIAMOND -2.724672e-02 -0.0486265648
## GT:CUPP-GH:dbCAN_4:DIAMOND -3.503949e-02 -0.0564193346
## PL:CUPP-GH:dbCAN_4:DIAMOND 1.290865e-02 -0.0119422657
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4:DIAMOND 1.495689e-02 -0.0098940263
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 6.358549e-03 -0.0183287667
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND -7.646490e-03 -0.0290263324
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 1.002388e-02 -0.0116354497
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND -1.065908e-02 -0.0320389179
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND -6.496910e-03 -0.0278767525
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 1.498564e-02 -0.0098652788
## AA:CUPP-GT:dbCAN_4:DIAMOND 2.830212e-04 -0.0244042942
## CBM:CUPP-GT:dbCAN_4:DIAMOND -9.868574e-02 -0.1200655784
## CE:CUPP-GT:dbCAN_4:DIAMOND 6.215909e-03 -0.0154434203
## GH:CUPP-GT:dbCAN_4:DIAMOND -2.980127e-02 -0.0511811146
## GT:CUPP-GT:dbCAN_4:DIAMOND -3.759404e-02 -0.0589738844
## PL:CUPP-GT:dbCAN_4:DIAMOND 1.035410e-02 -0.0144968155
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -8.598343e-03 -0.0363460273
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -2.260338e-02 -0.0474542993
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -4.933012e-03 -0.0300247834
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -2.561597e-02 -0.0504668847
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -2.145380e-02 -0.0463047194
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 2.874747e-05 -0.0278645952
## AA:CUPP-PL:dbCAN_4:DIAMOND -1.467387e-02 -0.0424215548
## CBM:CUPP-PL:dbCAN_4:DIAMOND -1.136426e-01 -0.1384935453
## CE:CUPP-PL:dbCAN_4:DIAMOND -8.740982e-03 -0.0338327540
## GH:CUPP-PL:dbCAN_4:DIAMOND -4.475816e-02 -0.0696090814
## GT:CUPP-PL:dbCAN_4:DIAMOND -5.255093e-02 -0.0774018513
## PL:CUPP-PL:dbCAN_4:DIAMOND -4.602789e-03 -0.0324961319
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub -1.400504e-02 -0.0386923543
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub 3.665331e-03 -0.0212644191
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub -1.701762e-02 -0.0417049397
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub -1.285546e-02 -0.0375427743
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub 8.627090e-03 -0.0191205944
## AA:CUPP-AA:dbCAN_4:dbCAN-sub -6.075528e-03 -0.0336767853
## CBM:CUPP-AA:dbCAN_4:dbCAN-sub -1.050443e-01 -0.1297316003
## CE:CUPP-AA:dbCAN_4:dbCAN-sub -1.426398e-04 -0.0250723896
## GH:CUPP-AA:dbCAN_4:dbCAN-sub -3.615982e-02 -0.0608471364
## GT:CUPP-AA:dbCAN_4:dbCAN-sub -4.395259e-02 -0.0686399063
## PL:CUPP-AA:dbCAN_4:dbCAN-sub 3.995553e-03 -0.0237521311
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:dbCAN-sub 1.767037e-02 -0.0039889596
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:dbCAN-sub -3.012585e-03 -0.0243924277
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:dbCAN-sub 1.149580e-03 -0.0202302624
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:dbCAN-sub 2.263213e-02 -0.0022187887
## AA:CUPP-CBM:dbCAN_4:dbCAN-sub 7.929511e-03 -0.0167578041
## CBM:CUPP-CBM:dbCAN_4:dbCAN-sub -9.103925e-02 -0.1124190883
## CE:CUPP-CBM:dbCAN_4:dbCAN-sub 1.386240e-02 -0.0077969302
## GH:CUPP-CBM:dbCAN_4:dbCAN-sub -2.215478e-02 -0.0435346245
## GT:CUPP-CBM:dbCAN_4:dbCAN-sub -2.994755e-02 -0.0513273943
## PL:CUPP-CBM:dbCAN_4:dbCAN-sub 1.800059e-02 -0.0068503254
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4:dbCAN-sub -2.068296e-02 -0.0423422843
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4:dbCAN-sub -1.652079e-02 -0.0381801189
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4:dbCAN-sub 4.961759e-03 -0.0201300121
## AA:CUPP-CE:dbCAN_4:dbCAN-sub -9.740858e-03 -0.0346706082
## CBM:CUPP-CE:dbCAN_4:dbCAN-sub -1.087096e-01 -0.1303689449
## CE:CUPP-CE:dbCAN_4:dbCAN-sub -3.807971e-03 -0.0257432260
## GH:CUPP-CE:dbCAN_4:dbCAN-sub -3.982515e-02 -0.0614844810
## GT:CUPP-CE:dbCAN_4:dbCAN-sub -4.761792e-02 -0.0692772509
## PL:CUPP-CE:dbCAN_4:dbCAN-sub 3.302227e-04 -0.0247615488
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub 4.162165e-03 -0.0172176770
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub 2.564471e-02 0.0007937967
## AA:CUPP-GH:dbCAN_4:dbCAN-sub 1.094210e-02 -0.0137452187
## CBM:CUPP-GH:dbCAN_4:dbCAN-sub -8.802666e-02 -0.1094065029
## CE:CUPP-GH:dbCAN_4:dbCAN-sub 1.687498e-02 -0.0047843448
## GH:CUPP-GH:dbCAN_4:dbCAN-sub -1.914220e-02 -0.0405220391
## GT:CUPP-GH:dbCAN_4:dbCAN-sub -2.693497e-02 -0.0483148089
## PL:CUPP-GH:dbCAN_4:dbCAN-sub 2.101318e-02 -0.0038377400
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:dbCAN-sub 2.148255e-02 -0.0033683686
## AA:CUPP-GT:dbCAN_4:dbCAN-sub 6.779931e-03 -0.0179073841
## CBM:CUPP-GT:dbCAN_4:dbCAN-sub -9.218883e-02 -0.1135686683
## CE:CUPP-GT:dbCAN_4:dbCAN-sub 1.271282e-02 -0.0089465101
## GH:CUPP-GT:dbCAN_4:dbCAN-sub -2.330436e-02 -0.0446842044
## GT:CUPP-GT:dbCAN_4:dbCAN-sub -3.109713e-02 -0.0524769742
## PL:CUPP-GT:dbCAN_4:dbCAN-sub 1.685101e-02 -0.0079999054
## AA:CUPP-PL:dbCAN_4:dbCAN-sub -1.470262e-02 -0.0424503023
## CBM:CUPP-PL:dbCAN_4:dbCAN-sub -1.136714e-01 -0.1385222928
## CE:CUPP-PL:dbCAN_4:dbCAN-sub -8.769730e-03 -0.0338615015
## GH:CUPP-PL:dbCAN_4:dbCAN-sub -4.478691e-02 -0.0696378289
## GT:CUPP-PL:dbCAN_4:dbCAN-sub -5.257968e-02 -0.0774305987
## PL:CUPP-PL:dbCAN_4:dbCAN-sub -4.631537e-03 -0.0325248794
## CBM:CUPP-AA:CUPP -9.896876e-02 -0.1236560728
## CE:CUPP-AA:CUPP 5.932888e-03 -0.0189968621
## GH:CUPP-AA:CUPP -3.008429e-02 -0.0547716089
## GT:CUPP-AA:CUPP -3.787706e-02 -0.0625643788
## PL:CUPP-AA:CUPP 1.007108e-02 -0.0176766036
## CE:CUPP-CBM:CUPP 1.049016e-01 0.0832423158
## GH:CUPP-CBM:CUPP 6.888446e-02 0.0475046215
## GT:CUPP-CBM:CUPP 6.109169e-02 0.0397118517
## PL:CUPP-CBM:CUPP 1.090398e-01 0.0841889206
## GH:CUPP-CE:CUPP -3.601718e-02 -0.0576765105
## GT:CUPP-CE:CUPP -4.380995e-02 -0.0654692803
## PL:CUPP-CE:CUPP 4.138193e-03 -0.0209535783
## GT:CUPP-GH:CUPP -7.792770e-03 -0.0291726122
## PL:CUPP-GH:CUPP 4.015537e-02 0.0153044567
## PL:CUPP-GT:CUPP 4.794814e-02 0.0230972266
## upr p adj
## CBM:dbCAN_4-AA:dbCAN_4 0.0102732227 0.9358363
## CE:dbCAN_4-AA:dbCAN_4 0.0285214403 1.0000000
## GH:dbCAN_4-AA:dbCAN_4 0.0083092356 0.7869144
## GT:dbCAN_4-AA:dbCAN_4 0.0120955442 0.9882219
## PL:dbCAN_4-AA:dbCAN_4 0.0355887770 0.9999999
## AA:dbCAN_4:HMMER-AA:dbCAN_4 0.0269774961 1.0000000
## CBM:dbCAN_4:HMMER-AA:dbCAN_4 -0.0223974483 0.0000000
## CE:dbCAN_4:HMMER-AA:dbCAN_4 0.0270730881 1.0000000
## GH:dbCAN_4:HMMER-AA:dbCAN_4 -0.0059103570 0.0013405
## GT:dbCAN_4:HMMER-AA:dbCAN_4 -0.0157738604 0.0000004
## PL:dbCAN_4:HMMER-AA:dbCAN_4 0.0355834245 0.9999999
## AA:dbCAN_4:DIAMOND-AA:dbCAN_4 0.0265869498 1.0000000
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4 0.0169579824 0.9999987
## CE:dbCAN_4:DIAMOND-AA:dbCAN_4 0.0261535854 1.0000000
## GH:dbCAN_4:DIAMOND-AA:dbCAN_4 0.0152042918 0.9999044
## GT:dbCAN_4:DIAMOND-AA:dbCAN_4 0.0177588416 0.9999999
## PL:dbCAN_4:DIAMOND-AA:dbCAN_4 0.0357761021 0.9999998
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4 0.0270313326 1.0000000
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4 0.0101123515 0.9276545
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4 0.0280251555 1.0000000
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4 0.0070997661 0.6492919
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4 0.0112619314 0.9722489
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4 0.0358048496 0.9999998
## AA:CUPP-AA:dbCAN_4 0.0209558051 1.0000000
## CBM:CUPP-AA:dbCAN_4 -0.0809268945 0.0000000
## CE:CUPP-AA:dbCAN_4 0.0242171850 1.0000000
## GH:CUPP-AA:dbCAN_4 -0.0120424307 0.0000112
## GT:CUPP-AA:dbCAN_4 -0.0198352005 0.0000000
## PL:CUPP-AA:dbCAN_4 0.0311733129 1.0000000
## CE:dbCAN_4-CBM:dbCAN_4 0.0396651124 0.2992614
## GH:dbCAN_4-CBM:dbCAN_4 0.0194158552 1.0000000
## GT:dbCAN_4-CBM:dbCAN_4 0.0232021639 1.0000000
## PL:dbCAN_4-CBM:dbCAN_4 0.0471061029 0.1652986
## AA:dbCAN_4:HMMER-CBM:dbCAN_4 0.0384776466 0.9613830
## CBM:dbCAN_4:HMMER-CBM:dbCAN_4 -0.0112908286 0.0000047
## CE:dbCAN_4:HMMER-CBM:dbCAN_4 0.0382167602 0.4882322
## GH:dbCAN_4:HMMER-CBM:dbCAN_4 0.0051962626 0.5113557
## GT:dbCAN_4:HMMER-CBM:dbCAN_4 -0.0046672407 0.0019244
## PL:dbCAN_4:HMMER-CBM:dbCAN_4 0.0471007504 0.1656595
## AA:dbCAN_4:DIAMOND-CBM:dbCAN_4 0.0380871002 0.9729112
## CBM:dbCAN_4:DIAMOND-CBM:dbCAN_4 0.0280646020 0.9999988
## CE:dbCAN_4:DIAMOND-CBM:dbCAN_4 0.0372972576 0.6200112
## GH:dbCAN_4:DIAMOND-CBM:dbCAN_4 0.0263109114 1.0000000
## GT:dbCAN_4:DIAMOND-CBM:dbCAN_4 0.0288654612 0.9999854
## PL:dbCAN_4:DIAMOND-CBM:dbCAN_4 0.0472934281 0.1530329
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 0.0385314831 0.9595412
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 0.0212189711 1.0000000
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 0.0391688277 0.3593567
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 0.0182063857 1.0000000
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 0.0223685510 1.0000000
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 0.0473221755 0.1512128
## AA:CUPP-CBM:dbCAN_4 0.0324559556 0.9999986
## CBM:CUPP-CBM:dbCAN_4 -0.0698202749 0.0000000
## CE:CUPP-CBM:dbCAN_4 0.0353608571 0.8572628
## GH:CUPP-CBM:dbCAN_4 -0.0009358110 0.0280843
## GT:CUPP-CBM:dbCAN_4 -0.0087285809 0.0000574
## PL:CUPP-CBM:dbCAN_4 0.0426906388 0.6326724
## GH:dbCAN_4-CE:dbCAN_4 0.0016895590 0.1252983
## GT:dbCAN_4-CE:dbCAN_4 0.0054758676 0.5417375
## PL:dbCAN_4-CE:dbCAN_4 0.0293411736 1.0000000
## AA:dbCAN_4:HMMER-CE:dbCAN_4 0.0207142978 1.0000000
## CBM:dbCAN_4:HMMER-CE:dbCAN_4 -0.0290171249 0.0000000
## CE:dbCAN_4:HMMER-CE:dbCAN_4 0.0204869032 1.0000000
## GH:dbCAN_4:HMMER-CE:dbCAN_4 -0.0125300336 0.0000016
## GT:dbCAN_4:HMMER-CE:dbCAN_4 -0.0223935369 0.0000000
## PL:dbCAN_4:HMMER-CE:dbCAN_4 0.0293358210 1.0000000
## AA:dbCAN_4:DIAMOND-CE:dbCAN_4 0.0203237515 1.0000000
## CBM:dbCAN_4:DIAMOND-CE:dbCAN_4 0.0103383058 0.9834821
## CE:dbCAN_4:DIAMOND-CE:dbCAN_4 0.0195674005 1.0000000
## GH:dbCAN_4:DIAMOND-CE:dbCAN_4 0.0085846152 0.9088184
## GT:dbCAN_4:DIAMOND-CE:dbCAN_4 0.0111391650 0.9942406
## PL:dbCAN_4:DIAMOND-CE:dbCAN_4 0.0295284987 1.0000000
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4 0.0207681343 1.0000000
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4 0.0034926749 0.2810887
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4 0.0214389706 1.0000000
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4 0.0004800895 0.0658779
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4 0.0046422548 0.4242196
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4 0.0295572462 1.0000000
## AA:CUPP-CE:dbCAN_4 0.0146926068 0.9996598
## CBM:CUPP-CE:dbCAN_4 -0.0875465711 0.0000000
## CE:CUPP-CE:dbCAN_4 0.0176310001 1.0000000
## GH:CUPP-CE:dbCAN_4 -0.0186621073 0.0000000
## GT:CUPP-CE:dbCAN_4 -0.0264548771 0.0000000
## PL:CUPP-CE:dbCAN_4 0.0249257095 1.0000000
## GT:dbCAN_4-GH:dbCAN_4 0.0251661510 1.0000000
## PL:dbCAN_4-GH:dbCAN_4 0.0490700901 0.0685357
## AA:dbCAN_4:HMMER-GH:dbCAN_4 0.0404416337 0.8457071
## CBM:dbCAN_4:HMMER-GH:dbCAN_4 -0.0093268415 0.0000327
## CE:dbCAN_4:HMMER-GH:dbCAN_4 0.0401807473 0.2434407
## GH:dbCAN_4:HMMER-GH:dbCAN_4 0.0071602497 0.7826806
## GT:dbCAN_4:HMMER-GH:dbCAN_4 -0.0027032536 0.0084760
## PL:dbCAN_4:HMMER-GH:dbCAN_4 0.0490647375 0.0687146
## AA:dbCAN_4:DIAMOND-GH:dbCAN_4 0.0400510873 0.8771925
## CBM:dbCAN_4:DIAMOND-GH:dbCAN_4 0.0300285891 0.9997425
## CE:dbCAN_4:DIAMOND-GH:dbCAN_4 0.0392612447 0.3477296
## GH:dbCAN_4:DIAMOND-GH:dbCAN_4 0.0282748985 0.9999975
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4 0.0308294483 0.9987429
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4 0.0492574152 0.0625152
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4 0.0404954702 0.8410349
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4 0.0231829582 1.0000000
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4 0.0411328148 0.1594620
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4 0.0201703728 1.0000000
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4 0.0243325382 1.0000000
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4 0.0492861627 0.0616320
## AA:CUPP-GH:dbCAN_4 0.0344199427 0.9998419
## CBM:CUPP-GH:dbCAN_4 -0.0678562878 0.0000000
## CE:CUPP-GH:dbCAN_4 0.0373248442 0.6160877
## GH:CUPP-GH:dbCAN_4 0.0010281761 0.0896361
## GT:CUPP-GH:dbCAN_4 -0.0067645938 0.0003369
## PL:CUPP-GH:dbCAN_4 0.0446546259 0.3916034
## PL:dbCAN_4-GT:dbCAN_4 0.0452837814 0.3224229
## AA:dbCAN_4:HMMER-GT:dbCAN_4 0.0366553250 0.9944052
## CBM:dbCAN_4:HMMER-GT:dbCAN_4 -0.0131131502 0.0000007
## CE:dbCAN_4:HMMER-GT:dbCAN_4 0.0363944387 0.7424275
## GH:dbCAN_4:HMMER-GT:dbCAN_4 0.0033739411 0.2728884
## GT:dbCAN_4:HMMER-GT:dbCAN_4 -0.0064895622 0.0004272
## PL:dbCAN_4:HMMER-GT:dbCAN_4 0.0452784289 0.3229827
## AA:dbCAN_4:DIAMOND-GT:dbCAN_4 0.0362647787 0.9966601
## CBM:dbCAN_4:DIAMOND-GT:dbCAN_4 0.0262422805 1.0000000
## CE:dbCAN_4:DIAMOND-GT:dbCAN_4 0.0354749360 0.8463330
## GH:dbCAN_4:DIAMOND-GT:dbCAN_4 0.0244885899 1.0000000
## GT:dbCAN_4:DIAMOND-GT:dbCAN_4 0.0270431397 1.0000000
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4 0.0454711065 0.3031680
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4 0.0367091615 0.9940114
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4 0.0193966496 1.0000000
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4 0.0373465061 0.6130024
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4 0.0163840642 1.0000000
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4 0.0205462295 1.0000000
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4 0.0454998540 0.3002721
## AA:CUPP-GT:dbCAN_4 0.0306336340 1.0000000
## CBM:CUPP-GT:dbCAN_4 -0.0716425964 0.0000000
## CE:CUPP-GT:dbCAN_4 0.0335385356 0.9691307
## GH:CUPP-GT:dbCAN_4 -0.0027581326 0.0081490
## GT:CUPP-GT:dbCAN_4 -0.0105509024 0.0000099
## PL:CUPP-GT:dbCAN_4 0.0408683173 0.8318053
## AA:dbCAN_4:HMMER-PL:dbCAN_4 0.0192828305 0.9999993
## CBM:dbCAN_4:HMMER-PL:dbCAN_4 -0.0300749384 0.0000000
## CE:dbCAN_4:HMMER-PL:dbCAN_4 0.0193940173 1.0000000
## GH:dbCAN_4:HMMER-PL:dbCAN_4 -0.0135878472 0.0000032
## GT:dbCAN_4:HMMER-PL:dbCAN_4 -0.0234513505 0.0000000
## PL:dbCAN_4:HMMER-PL:dbCAN_4 0.0278879902 1.0000000
## AA:dbCAN_4:DIAMOND-PL:dbCAN_4 0.0188922841 0.9999980
## CBM:dbCAN_4:DIAMOND-PL:dbCAN_4 0.0092804922 0.8692149
## CE:dbCAN_4:DIAMOND-PL:dbCAN_4 0.0184745146 1.0000000
## GH:dbCAN_4:DIAMOND-PL:dbCAN_4 0.0075268016 0.6948106
## GT:dbCAN_4:DIAMOND-PL:dbCAN_4 0.0100813514 0.9223645
## PL:dbCAN_4:DIAMOND-PL:dbCAN_4 0.0280806678 1.0000000
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4 0.0193366670 0.9999994
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4 0.0024348613 0.1547224
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4 0.0203460847 1.0000000
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4 -0.0005777241 0.0369982
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4 0.0035844412 0.2420435
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4 0.0281094153 1.0000000
## AA:CUPP-PL:dbCAN_4 0.0132611395 0.9837392
## CBM:CUPP-PL:dbCAN_4 -0.0886043847 0.0000000
## CE:CUPP-PL:dbCAN_4 0.0165381142 0.9999917
## GH:CUPP-PL:dbCAN_4 -0.0197199208 0.0000000
## GT:CUPP-PL:dbCAN_4 -0.0275126907 0.0000000
## PL:CUPP-PL:dbCAN_4 0.0234778786 1.0000000
## CBM:dbCAN_4:HMMER-AA:dbCAN_4:HMMER -0.0217736867 0.0000000
## CE:dbCAN_4:HMMER-AA:dbCAN_4:HMMER 0.0276968497 1.0000000
## GH:dbCAN_4:HMMER-AA:dbCAN_4:HMMER -0.0052865954 0.0020647
## GT:dbCAN_4:HMMER-AA:dbCAN_4:HMMER -0.0151500987 0.0000007
## PL:dbCAN_4:HMMER-AA:dbCAN_4:HMMER 0.0362071861 0.9999993
## AA:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 0.0272107114 1.0000000
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 0.0175817440 0.9999998
## CE:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 0.0267773471 1.0000000
## GH:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 0.0158280534 0.9999756
## GT:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 0.0183826032 1.0000000
## PL:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 0.0363998638 0.9999988
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 0.0276550942 1.0000000
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 0.0107361131 0.9556850
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 0.0286489172 1.0000000
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 0.0077235277 0.7234282
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 0.0118856930 0.9851775
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 0.0364286112 0.9999987
## AA:CUPP-AA:dbCAN_4:HMMER 0.0215795667 1.0000000
## CBM:CUPP-AA:dbCAN_4:HMMER -0.0803031329 0.0000000
## CE:CUPP-AA:dbCAN_4:HMMER 0.0248409466 1.0000000
## GH:CUPP-AA:dbCAN_4:HMMER -0.0114186690 0.0000190
## GT:CUPP-AA:dbCAN_4:HMMER -0.0192114389 0.0000000
## PL:CUPP-AA:dbCAN_4:HMMER 0.0317970745 1.0000000
## CE:dbCAN_4:HMMER-CBM:dbCAN_4:HMMER 0.0708874312 0.0000000
## GH:dbCAN_4:HMMER-CBM:dbCAN_4:HMMER 0.0378669336 0.4677385
## GT:dbCAN_4:HMMER-CBM:dbCAN_4:HMMER 0.0280034303 0.9999990
## PL:dbCAN_4:HMMER-CBM:dbCAN_4:HMMER 0.0797714214 0.0000000
## AA:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 0.0707577712 0.0000000
## CBM:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 0.0607352730 0.0000000
## CE:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 0.0699679285 0.0000000
## GH:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 0.0589815824 0.0000000
## GT:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 0.0615361322 0.0000000
## PL:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 0.0799640990 0.0000000
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 0.0712021540 0.0000000
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 0.0538896421 0.0000056
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 0.0718394986 0.0000000
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 0.0508770567 0.0001010
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 0.0550392220 0.0000017
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 0.0799928465 0.0000000
## AA:CUPP-CBM:dbCAN_4:HMMER 0.0651266265 0.0000004
## CBM:CUPP-CBM:dbCAN_4:HMMER -0.0371496039 0.0000000
## CE:CUPP-CBM:dbCAN_4:HMMER 0.0680315281 0.0000000
## GH:CUPP-CBM:dbCAN_4:HMMER 0.0317348599 0.9944833
## GT:CUPP-CBM:dbCAN_4:HMMER 0.0239420901 1.0000000
## PL:CUPP-CBM:dbCAN_4:HMMER 0.0753613098 0.0000000
## GH:dbCAN_4:HMMER-CE:dbCAN_4:HMMER -0.0110816814 0.0000068
## GT:dbCAN_4:HMMER-CE:dbCAN_4:HMMER -0.0209451847 0.0000000
## PL:dbCAN_4:HMMER-CE:dbCAN_4:HMMER 0.0307841733 1.0000000
## AA:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 0.0217721037 1.0000000
## CBM:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 0.0117866580 0.9978921
## CE:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 0.0210157528 1.0000000
## GH:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 0.0100329674 0.9765039
## GT:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 0.0125875172 0.9995119
## PL:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 0.0309768509 1.0000000
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 0.0222164865 1.0000000
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 0.0049410271 0.4655378
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 0.0228873229 1.0000000
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 0.0019284417 0.1409579
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 0.0060906070 0.6298245
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 0.0310055984 1.0000000
## AA:CUPP-CE:dbCAN_4:HMMER 0.0161409590 0.9999831
## CBM:CUPP-CE:dbCAN_4:HMMER -0.0860982189 0.0000000
## CE:CUPP-CE:dbCAN_4:HMMER 0.0190793523 1.0000000
## GH:CUPP-CE:dbCAN_4:HMMER -0.0172137551 0.0000000
## GT:CUPP-CE:dbCAN_4:HMMER -0.0250065249 0.0000000
## PL:CUPP-CE:dbCAN_4:HMMER 0.0263740617 1.0000000
## GT:dbCAN_4:HMMER-GH:dbCAN_4:HMMER 0.0115163390 0.9974327
## PL:dbCAN_4:HMMER-GH:dbCAN_4:HMMER 0.0632843301 0.0000032
## AA:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 0.0542706799 0.0026908
## CBM:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 0.0442481817 0.0195966
## CE:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 0.0534808373 0.0000166
## GH:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 0.0424944911 0.0584249
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 0.0450490409 0.0113576
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 0.0634770078 0.0000027
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 0.0547150628 0.0019900
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 0.0374025508 0.5347328
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 0.0553524074 0.0000026
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 0.0343899654 0.9011552
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 0.0385521308 0.3737884
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 0.0635057553 0.0000026
## AA:CUPP-GH:dbCAN_4:HMMER 0.0486395353 0.0722308
## CBM:CUPP-GH:dbCAN_4:HMMER -0.0536366952 0.0000000
## CE:CUPP-GH:dbCAN_4:HMMER 0.0515444368 0.0001008
## GH:CUPP-GH:dbCAN_4:HMMER 0.0152477687 0.9999998
## GT:CUPP-GH:dbCAN_4:HMMER 0.0074549988 0.8163489
## PL:CUPP-GH:dbCAN_4:HMMER 0.0588742185 0.0001240
## PL:dbCAN_4:HMMER-GT:dbCAN_4:HMMER 0.0731478335 0.0000000
## AA:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 0.0641341833 0.0000010
## CBM:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 0.0541116850 0.0000045
## CE:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 0.0633443406 0.0000000
## GH:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 0.0523579945 0.0000252
## GT:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 0.0549125443 0.0000020
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 0.0733405111 0.0000000
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 0.0645785661 0.0000007
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 0.0472660541 0.0021851
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 0.0652159107 0.0000000
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 0.0442534687 0.0195279
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 0.0484156341 0.0008631
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 0.0733692586 0.0000000
## AA:CUPP-GT:dbCAN_4:HMMER 0.0585030386 0.0001225
## CBM:CUPP-GT:dbCAN_4:HMMER -0.0437731919 0.0000000
## CE:CUPP-GT:dbCAN_4:HMMER 0.0614079401 0.0000000
## GH:CUPP-GT:dbCAN_4:HMMER 0.0251112720 1.0000000
## GT:CUPP-GT:dbCAN_4:HMMER 0.0173185022 1.0000000
## PL:CUPP-GT:dbCAN_4:HMMER 0.0687377219 0.0000000
## AA:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 0.0188976367 0.9999981
## CBM:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 0.0092858447 0.8696296
## CE:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 0.0184798671 1.0000000
## GH:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 0.0075321541 0.6954385
## GT:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 0.0100867039 0.9226600
## PL:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 0.0280860203 1.0000000
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 0.0193420195 0.9999994
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 0.0024402138 0.1550659
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 0.0203514372 1.0000000
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER -0.0005723716 0.0371036
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 0.0035897938 0.2425146
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 0.0281147678 1.0000000
## AA:CUPP-PL:dbCAN_4:HMMER 0.0132664920 0.9838206
## CBM:CUPP-PL:dbCAN_4:HMMER -0.0885990322 0.0000000
## CE:CUPP-PL:dbCAN_4:HMMER 0.0165434667 0.9999918
## GH:CUPP-PL:dbCAN_4:HMMER -0.0197145683 0.0000000
## GT:CUPP-PL:dbCAN_4:HMMER -0.0275073382 0.0000000
## PL:CUPP-PL:dbCAN_4:HMMER 0.0234832311 1.0000000
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND 0.0179722903 1.0000000
## CE:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND 0.0271678934 1.0000000
## GH:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND 0.0162185997 0.9999905
## GT:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND 0.0187731496 1.0000000
## PL:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND 0.0367904101 0.9999969
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 0.0280456406 1.0000000
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 0.0111266594 0.9685387
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 0.0290394635 1.0000000
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 0.0081140740 0.7665618
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 0.0122762394 0.9904150
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 0.0368191576 0.9999966
## AA:CUPP-AA:dbCAN_4:DIAMOND 0.0219701131 1.0000000
## CBM:CUPP-AA:dbCAN_4:DIAMOND -0.0799125866 0.0000000
## CE:CUPP-AA:dbCAN_4:DIAMOND 0.0252314930 1.0000000
## GH:CUPP-AA:dbCAN_4:DIAMOND -0.0110281227 0.0000264
## GT:CUPP-AA:dbCAN_4:DIAMOND -0.0188208926 0.0000000
## PL:CUPP-AA:dbCAN_4:DIAMOND 0.0321876209 1.0000000
## CE:dbCAN_4:DIAMOND-CBM:dbCAN_4:DIAMOND 0.0306124979 0.9996159
## GH:dbCAN_4:DIAMOND-CBM:dbCAN_4:DIAMOND 0.0196261517 1.0000000
## GT:dbCAN_4:DIAMOND-CBM:dbCAN_4:DIAMOND 0.0221807015 1.0000000
## PL:dbCAN_4:DIAMOND-CBM:dbCAN_4:DIAMOND 0.0406086684 0.8542000
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 0.0318467234 0.9999998
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 0.0145342114 0.9999979
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 0.0324840680 0.9912000
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 0.0115216260 0.9974549
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 0.0156837914 1.0000000
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 0.0406374159 0.8518103
## AA:CUPP-CBM:dbCAN_4:DIAMOND 0.0257711959 1.0000000
## CBM:CUPP-CBM:dbCAN_4:DIAMOND -0.0765050346 0.0000000
## CE:CUPP-CBM:dbCAN_4:DIAMOND 0.0286760974 0.9999973
## GH:CUPP-CBM:dbCAN_4:DIAMOND -0.0076205707 0.0001583
## GT:CUPP-CBM:dbCAN_4:DIAMOND -0.0154133406 0.0000001
## PL:CUPP-CBM:dbCAN_4:DIAMOND 0.0360058791 0.9983667
## GH:dbCAN_4:DIAMOND-CE:dbCAN_4:DIAMOND 0.0109524700 0.9925053
## GT:dbCAN_4:DIAMOND-CE:dbCAN_4:DIAMOND 0.0135070198 0.9999360
## PL:dbCAN_4:DIAMOND-CE:dbCAN_4:DIAMOND 0.0318963536 1.0000000
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 0.0231359892 1.0000000
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 0.0058605297 0.5970520
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 0.0238068255 1.0000000
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 0.0028479443 0.2152224
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 0.0070101097 0.7532024
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 0.0319251010 0.9999999
## AA:CUPP-CE:dbCAN_4:DIAMOND 0.0170604617 0.9999985
## CBM:CUPP-CE:dbCAN_4:DIAMOND -0.0851787163 0.0000000
## CE:CUPP-CE:dbCAN_4:DIAMOND 0.0199988549 1.0000000
## GH:CUPP-CE:dbCAN_4:DIAMOND -0.0162942524 0.0000000
## GT:CUPP-CE:dbCAN_4:DIAMOND -0.0240870223 0.0000000
## PL:CUPP-CE:dbCAN_4:DIAMOND 0.0272935643 1.0000000
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND 0.0239343921 1.0000000
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND 0.0423623590 0.6725888
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 0.0336004140 0.9999724
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 0.0162879020 1.0000000
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 0.0342377586 0.9395204
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 0.0132753166 0.9999263
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 0.0174374819 1.0000000
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 0.0423911064 0.6691389
## AA:CUPP-GH:dbCAN_4:DIAMOND 0.0275248865 1.0000000
## CBM:CUPP-GH:dbCAN_4:DIAMOND -0.0747513440 0.0000000
## CE:CUPP-GH:dbCAN_4:DIAMOND 0.0304297880 0.9997377
## GH:CUPP-GH:dbCAN_4:DIAMOND -0.0058668801 0.0007241
## GT:CUPP-GH:dbCAN_4:DIAMOND -0.0136596500 0.0000004
## PL:CUPP-GH:dbCAN_4:DIAMOND 0.0377595697 0.9848238
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4:DIAMOND 0.0398078092 0.9115298
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 0.0310458641 1.0000000
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 0.0137333522 0.9999773
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 0.0316832088 0.9972987
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 0.0107207668 0.9915067
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 0.0148829321 0.9999993
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 0.0398365566 0.9097818
## AA:CUPP-GT:dbCAN_4:DIAMOND 0.0249703366 1.0000000
## CBM:CUPP-GT:dbCAN_4:DIAMOND -0.0773058938 0.0000000
## CE:CUPP-GT:dbCAN_4:DIAMOND 0.0278752382 0.9999998
## GH:CUPP-GT:dbCAN_4:DIAMOND -0.0084214299 0.0000764
## GT:CUPP-GT:dbCAN_4:DIAMOND -0.0162141998 0.0000000
## PL:CUPP-GT:dbCAN_4:DIAMOND 0.0352050199 0.9995562
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 0.0191493418 0.9999990
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 0.0022475362 0.1430570
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 0.0201587596 1.0000000
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -0.0007650492 0.0334708
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 0.0033971161 0.2259316
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 0.0279220902 1.0000000
## AA:CUPP-PL:dbCAN_4:DIAMOND 0.0130738143 0.9806781
## CBM:CUPP-PL:dbCAN_4:DIAMOND -0.0887917098 0.0000000
## CE:CUPP-PL:dbCAN_4:DIAMOND 0.0163507890 0.9999869
## GH:CUPP-PL:dbCAN_4:DIAMOND -0.0199072460 0.0000000
## GT:CUPP-PL:dbCAN_4:DIAMOND -0.0277000158 0.0000000
## PL:CUPP-PL:dbCAN_4:DIAMOND 0.0232905534 1.0000000
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub 0.0106822766 0.9536454
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub 0.0285950807 1.0000000
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub 0.0076696912 0.7172573
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub 0.0118318566 0.9843018
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub 0.0363747748 0.9999989
## AA:CUPP-AA:dbCAN_4:dbCAN-sub 0.0215257303 1.0000000
## CBM:CUPP-AA:dbCAN_4:dbCAN-sub -0.0803569694 0.0000000
## CE:CUPP-AA:dbCAN_4:dbCAN-sub 0.0247871101 1.0000000
## GH:CUPP-AA:dbCAN_4:dbCAN-sub -0.0114725055 0.0000182
## GT:CUPP-AA:dbCAN_4:dbCAN-sub -0.0192652754 0.0000000
## PL:CUPP-AA:dbCAN_4:dbCAN-sub 0.0317432380 1.0000000
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:dbCAN-sub 0.0393296989 0.3392410
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:dbCAN-sub 0.0183672569 1.0000000
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:dbCAN-sub 0.0225294223 1.0000000
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:dbCAN-sub 0.0474830468 0.1413278
## AA:CUPP-CBM:dbCAN_4:dbCAN-sub 0.0326168268 0.9999977
## CBM:CUPP-CBM:dbCAN_4:dbCAN-sub -0.0696594037 0.0000000
## CE:CUPP-CBM:dbCAN_4:dbCAN-sub 0.0355217283 0.8417153
## GH:CUPP-CBM:dbCAN_4:dbCAN-sub -0.0007749398 0.0311036
## GT:CUPP-CBM:dbCAN_4:dbCAN-sub -0.0085677097 0.0000667
## PL:CUPP-CBM:dbCAN_4:dbCAN-sub 0.0428515100 0.6127730
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4:dbCAN-sub 0.0009763742 0.0865572
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4:dbCAN-sub 0.0051385396 0.4934353
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4:dbCAN-sub 0.0300535309 1.0000000
## AA:CUPP-CE:dbCAN_4:dbCAN-sub 0.0151888916 0.9998668
## CBM:CUPP-CE:dbCAN_4:dbCAN-sub -0.0870502864 0.0000000
## CE:CUPP-CE:dbCAN_4:dbCAN-sub 0.0181272848 1.0000000
## GH:CUPP-CE:dbCAN_4:dbCAN-sub -0.0181658225 0.0000000
## GT:CUPP-CE:dbCAN_4:dbCAN-sub -0.0259585924 0.0000000
## PL:CUPP-CE:dbCAN_4:dbCAN-sub 0.0254219942 1.0000000
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub 0.0255420077 1.0000000
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub 0.0504956322 0.0329565
## AA:CUPP-GH:dbCAN_4:dbCAN-sub 0.0356294122 0.9986814
## CBM:CUPP-GH:dbCAN_4:dbCAN-sub -0.0666468183 0.0000000
## CE:CUPP-GH:dbCAN_4:dbCAN-sub 0.0385343137 0.4437169
## GH:CUPP-GH:dbCAN_4:dbCAN-sub 0.0022376456 0.1656493
## GT:CUPP-GH:dbCAN_4:dbCAN-sub -0.0055551243 0.0009382
## PL:CUPP-GH:dbCAN_4:dbCAN-sub 0.0458640955 0.2649906
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:dbCAN-sub 0.0463334668 0.2235242
## AA:CUPP-GT:dbCAN_4:dbCAN-sub 0.0314672468 0.9999999
## CBM:CUPP-GT:dbCAN_4:dbCAN-sub -0.0708089836 0.0000000
## CE:CUPP-GT:dbCAN_4:dbCAN-sub 0.0343721484 0.9320575
## GH:CUPP-GT:dbCAN_4:dbCAN-sub -0.0019245198 0.0146118
## GT:CUPP-GT:dbCAN_4:dbCAN-sub -0.0097172896 0.0000225
## PL:CUPP-GT:dbCAN_4:dbCAN-sub 0.0417019301 0.7485056
## AA:CUPP-PL:dbCAN_4:dbCAN-sub 0.0130450668 0.9801703
## CBM:CUPP-PL:dbCAN_4:dbCAN-sub -0.0888204573 0.0000000
## CE:CUPP-PL:dbCAN_4:dbCAN-sub 0.0163220416 0.9999859
## GH:CUPP-PL:dbCAN_4:dbCAN-sub -0.0199359934 0.0000000
## GT:CUPP-PL:dbCAN_4:dbCAN-sub -0.0277287633 0.0000000
## PL:CUPP-PL:dbCAN_4:dbCAN-sub 0.0232618060 1.0000000
## CBM:CUPP-AA:CUPP -0.0742814419 0.0000000
## CE:CUPP-AA:CUPP 0.0308626376 1.0000000
## GH:CUPP-AA:CUPP -0.0053969780 0.0019143
## GT:CUPP-AA:CUPP -0.0131897479 0.0000041
## PL:CUPP-AA:CUPP 0.0378187655 0.9999693
## CE:CUPP-CBM:CUPP 0.1265609743 0.0000000
## GH:CUPP-CBM:CUPP 0.0902643062 0.0000000
## GT:CUPP-CBM:CUPP 0.0824715363 0.0000000
## PL:CUPP-CBM:CUPP 0.1338907560 0.0000000
## GH:CUPP-CE:CUPP -0.0143578520 0.0000002
## GT:CUPP-CE:CUPP -0.0221506218 0.0000000
## PL:CUPP-CE:CUPP 0.0292299648 1.0000000
## GT:CUPP-GH:CUPP 0.0135870725 0.9999665
## PL:CUPP-GH:CUPP 0.0650062922 0.0000007
## PL:CUPP-GT:CUPP 0.0727990620 0.00000007 CAZy class multilabel classification
A single CAZyme can be included in multiple CAZy classes leading to the multilabel classification of CAZymes. To address this and evaluate the multilabel classification of CAZy classes the Rand Index (RI) and Adjusted Rand Index (ARI) were calculated.
The RI is the measure of accuracy across all potential classifications of a protein. The RI ranges from 0 (no correct annotations) to 1 (all annotations correct). The ARI is the RI adjusted for chance, where 0 is the equivalent to assigning the CAZy class annotations randomly, -1 where the annotations are systematically handed out incorrectly and 1 where the annotations are all correct.
One-way ANOVA to test for statistically significant differences between the means.
## Df Sum Sq Mean Sq F value Pr(>F)
## Prediction_tool 4 9.0 2.2577 334.7 <2e-16 ***
## Residuals 79995 539.6 0.0067
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1The means are statistically significantly different, therefore, use a post hoc Turkey HSD test to determine between which tools the means are significantly difference.
## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Rand_index_freq ~ Prediction_tool, data = class_ri_ari_raw_df)
##
## $Prediction_tool
## diff lwr upr
## dbCAN_4:HMMER-dbCAN_4 -0.0129166667 -1.542143e-02 -0.0104119078
## dbCAN_4:DIAMOND-dbCAN_4 0.0024416667 -6.309219e-05 0.0049464255
## dbCAN_4:dbCAN-sub-dbCAN_4 -0.0005416667 -3.046426e-03 0.0019630922
## CUPP-dbCAN_4 -0.0257125000 -2.821726e-02 -0.0232077411
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.0153583333 1.285357e-02 0.0178630922
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.0123750000 9.870241e-03 0.0148797589
## CUPP-dbCAN_4:HMMER -0.0127958333 -1.530059e-02 -0.0102910745
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND -0.0029833333 -5.488092e-03 -0.0004785745
## CUPP-dbCAN_4:DIAMOND -0.0281541667 -3.065893e-02 -0.0256494078
## CUPP-dbCAN_4:dbCAN-sub -0.0251708333 -2.767559e-02 -0.0226660745
## p adj
## dbCAN_4:HMMER-dbCAN_4 0.0000000
## dbCAN_4:DIAMOND-dbCAN_4 0.0602133
## dbCAN_4:dbCAN-sub-dbCAN_4 0.9766300
## CUPP-dbCAN_4 0.0000000
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.0000000
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.0000000
## CUPP-dbCAN_4:HMMER 0.0000000
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND 0.0101938
## CUPP-dbCAN_4:DIAMOND 0.0000000
## CUPP-dbCAN_4:dbCAN-sub 0.0000000One-way ANOVA to test for statistically significant differences between the means.
## Df Sum Sq Mean Sq F value Pr(>F)
## Prediction_tool 4 61 15.247 292.7 <2e-16 ***
## Residuals 79995 4166 0.052
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1The means are statistically significantly different, therefore, use a post hoc Turkey HSD test to determine between which tools the means are significantly difference.
## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Adjusted_Rand_index_freq ~ Prediction_tool, data = class_ri_ari_raw_df)
##
## $Prediction_tool
## diff lwr upr
## dbCAN_4:HMMER-dbCAN_4 -0.035437111 -0.0423970268 -0.0284771947
## dbCAN_4:DIAMOND-dbCAN_4 0.006146445 -0.0008134707 0.0131063614
## dbCAN_4:dbCAN-sub-dbCAN_4 -0.001345990 -0.0083059060 0.0056139260
## CUPP-dbCAN_4 -0.066299187 -0.0732591030 -0.0593392710
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.041583556 0.0346236401 0.0485434721
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.034091121 0.0271312047 0.0410510368
## CUPP-dbCAN_4:HMMER -0.030862076 -0.0378219923 -0.0239021602
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND -0.007492435 -0.0144523514 -0.0005325193
## CUPP-dbCAN_4:DIAMOND -0.072445632 -0.0794055484 -0.0654857163
## CUPP-dbCAN_4:dbCAN-sub -0.064953197 -0.0719131130 -0.0579932810
## p adj
## dbCAN_4:HMMER-dbCAN_4 0.0000000
## dbCAN_4:DIAMOND-dbCAN_4 0.1128327
## dbCAN_4:dbCAN-sub-dbCAN_4 0.9845707
## CUPP-dbCAN_4 0.0000000
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.0000000
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.0000000
## CUPP-dbCAN_4:HMMER 0.0000000
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND 0.0274675
## CUPP-dbCAN_4:DIAMOND 0.0000000
## CUPP-dbCAN_4:dbCAN-sub 0.00000008 CAZy class taxonomic performance
8.1 Across all of CAZy
8.1.1 Specificity
| Prediction_tool | Mean | Standard Deviation | Lower CI | Upper CI | Tax_group |
|---|---|---|---|---|---|
| dbCAN_4 | 0.9936 | 0.0267 | 0.9910 | 0.9962 | All |
| dbCAN_4:HMMER | 0.9941 | 0.0262 | 0.9915 | 0.9966 | All |
| dbCAN_4:DIAMOND | 0.9915 | 0.0285 | 0.9888 | 0.9943 | All |
| dbCAN_4:dbCAN-sub | 0.9931 | 0.0269 | 0.9905 | 0.9957 | All |
| CUPP | 0.9953 | 0.0246 | 0.9929 | 0.9977 | All |
| dbCAN_4 | 0.9958 | 0.0137 | 0.9939 | 0.9977 | Bacteria |
| dbCAN_4:HMMER | 0.9962 | 0.0133 | 0.9944 | 0.9981 | Bacteria |
| dbCAN_4:DIAMOND | 0.9942 | 0.0173 | 0.9918 | 0.9966 | Bacteria |
| dbCAN_4:dbCAN-sub | 0.9954 | 0.0139 | 0.9935 | 0.9973 | Bacteria |
| CUPP | 0.9970 | 0.0128 | 0.9952 | 0.9988 | Bacteria |
| dbCAN_4 | 0.9916 | 0.0348 | 0.9868 | 0.9963 | Eukaryote |
| dbCAN_4:HMMER | 0.9920 | 0.0341 | 0.9874 | 0.9967 | Eukaryote |
| dbCAN_4:DIAMOND | 0.9890 | 0.0360 | 0.9841 | 0.9939 | Eukaryote |
| dbCAN_4:dbCAN-sub | 0.9908 | 0.0350 | 0.9861 | 0.9956 | Eukaryote |
| CUPP | 0.9937 | 0.0320 | 0.9894 | 0.9981 | Eukaryote |
8.1.2 Sensitivity
| Prediction_tool | Mean | Standard Deviation | Lower CI | Upper CI | Tax_group |
|---|---|---|---|---|---|
| dbCAN_4 | 0.9477 | 0.1076 | 0.9327 | 0.9626 | Bacteria |
| dbCAN_4:HMMER | 0.8545 | 0.1946 | 0.8275 | 0.8816 | Bacteria |
| dbCAN_4:DIAMOND | 0.9317 | 0.1461 | 0.9114 | 0.9520 | Bacteria |
| dbCAN_4:dbCAN-sub | 0.9558 | 0.1011 | 0.9417 | 0.9699 | Bacteria |
| CUPP | 0.7168 | 0.3818 | 0.6637 | 0.7699 | Bacteria |
| dbCAN_4 | 0.9234 | 0.1457 | 0.9036 | 0.9433 | Eukaryote |
| dbCAN_4:HMMER | 0.8317 | 0.2562 | 0.7968 | 0.8665 | Eukaryote |
| dbCAN_4:DIAMOND | 0.9831 | 0.0487 | 0.9765 | 0.9898 | Eukaryote |
| dbCAN_4:dbCAN-sub | 0.9189 | 0.1433 | 0.8994 | 0.9384 | Eukaryote |
| CUPP | 0.7121 | 0.3682 | 0.6620 | 0.7622 | Eukaryote |
8.1.3 Precision
| Prediction_tool | Mean | Standard Deviation | Lower CI | Upper CI | Tax_group |
|---|---|---|---|---|---|
| dbCAN_4 | 0.9783 | 0.0746 | 0.9680 | 0.9887 | Bacteria |
| dbCAN_4:HMMER | 0.9755 | 0.0855 | 0.9636 | 0.9873 | Bacteria |
| dbCAN_4:DIAMOND | 0.9734 | 0.1103 | 0.9580 | 0.9887 | Bacteria |
| dbCAN_4:dbCAN-sub | 0.9767 | 0.0751 | 0.9663 | 0.9872 | Bacteria |
| CUPP | 0.7806 | 0.4022 | 0.7246 | 0.8365 | Bacteria |
| dbCAN_4 | 0.9589 | 0.1086 | 0.9442 | 0.9737 | Eukaryote |
| dbCAN_4:HMMER | 0.9483 | 0.1511 | 0.9277 | 0.9688 | Eukaryote |
| dbCAN_4:DIAMOND | 0.9537 | 0.1191 | 0.9375 | 0.9699 | Eukaryote |
| dbCAN_4:dbCAN-sub | 0.9524 | 0.1182 | 0.9364 | 0.9685 | Eukaryote |
| CUPP | 0.7765 | 0.3957 | 0.7227 | 0.8304 | Eukaryote |
8.1.4 F1-score
| Prediction_tool | Mean | Standard Deviation | Lower CI | Upper CI | Tax_group |
|---|---|---|---|---|---|
| dbCAN_4 | 0.9567 | 0.0853 | 0.9449 | 0.9686 | Bacteria |
| dbCAN_4:HMMER | 0.8949 | 0.1487 | 0.8742 | 0.9156 | Bacteria |
| dbCAN_4:DIAMOND | 0.9432 | 0.1237 | 0.9260 | 0.9604 | Bacteria |
| dbCAN_4:dbCAN-sub | 0.9607 | 0.0815 | 0.9493 | 0.9720 | Bacteria |
| CUPP | 0.7409 | 0.3859 | 0.6872 | 0.7946 | Bacteria |
| dbCAN_4 | 0.9301 | 0.1179 | 0.9140 | 0.9461 | Eukaryote |
| dbCAN_4:HMMER | 0.8591 | 0.2146 | 0.8299 | 0.8883 | Eukaryote |
| dbCAN_4:DIAMOND | 0.9629 | 0.0818 | 0.9517 | 0.9740 | Eukaryote |
| dbCAN_4:dbCAN-sub | 0.9249 | 0.1207 | 0.9085 | 0.9413 | Eukaryote |
| CUPP | 0.7370 | 0.3750 | 0.6860 | 0.7880 | Eukaryote |
8.1.5 Accuracy
| Prediction_tool | Mean | Standard Deviation | Lower CI | Upper CI | Tax_group |
|---|---|---|---|---|---|
| dbCAN_4 | 0.9855 | 0.0392 | 0.9801 | 0.9910 | Bacteria |
| dbCAN_4:HMMER | 0.9684 | 0.0473 | 0.9618 | 0.9750 | Bacteria |
| dbCAN_4:DIAMOND | 0.9839 | 0.0400 | 0.9784 | 0.9895 | Bacteria |
| dbCAN_4:dbCAN-sub | 0.9864 | 0.0359 | 0.9814 | 0.9914 | Bacteria |
| CUPP | 0.9516 | 0.0743 | 0.9413 | 0.9620 | Bacteria |
| dbCAN_4 | 0.9822 | 0.0252 | 0.9788 | 0.9857 | Eukaryote |
| dbCAN_4:HMMER | 0.9695 | 0.0325 | 0.9650 | 0.9739 | Eukaryote |
| dbCAN_4:DIAMOND | 0.9900 | 0.0226 | 0.9870 | 0.9931 | Eukaryote |
| dbCAN_4:dbCAN-sub | 0.9803 | 0.0264 | 0.9767 | 0.9839 | Eukaryote |
| CUPP | 0.9559 | 0.0466 | 0.9496 | 0.9623 | Eukaryote |
8.2 Per CAZy class
8.2.1 Specificity
| Prediction_tool | Mean | Standard Deviation | LowerCI | UpperCI | Tax_group | CAZy_class |
|---|---|---|---|---|---|---|
| dbCAN_4 | 0.9927 | 0.0240 | 0.9873 | 0.9980 | All | GH |
| dbCAN_4:HMMER | 0.9939 | 0.0224 | 0.9889 | 0.9988 | All | GH |
| dbCAN_4:DIAMOND | 0.9864 | 0.0279 | 0.9802 | 0.9927 | All | GH |
| dbCAN_4:dbCAN-sub | 0.9924 | 0.0238 | 0.9871 | 0.9977 | All | GH |
| CUPP | 0.9933 | 0.0212 | 0.9886 | 0.9980 | All | GH |
| dbCAN_4 | 0.9933 | 0.0141 | 0.9888 | 0.9978 | Bacteria | GH |
| dbCAN_4:HMMER | 0.9954 | 0.0124 | 0.9914 | 0.9993 | Bacteria | GH |
| dbCAN_4:DIAMOND | 0.9891 | 0.0196 | 0.9829 | 0.9954 | Bacteria | GH |
| dbCAN_4:dbCAN-sub | 0.9927 | 0.0143 | 0.9881 | 0.9973 | Bacteria | GH |
| CUPP | 0.9935 | 0.0140 | 0.9890 | 0.9980 | Bacteria | GH |
| dbCAN_4 | 0.9920 | 0.0312 | 0.9821 | 1.0020 | Eukaryote | GH |
| dbCAN_4:HMMER | 0.9923 | 0.0293 | 0.9830 | 1.0017 | Eukaryote | GH |
| dbCAN_4:DIAMOND | 0.9837 | 0.0344 | 0.9727 | 0.9947 | Eukaryote | GH |
| dbCAN_4:dbCAN-sub | 0.9921 | 0.0308 | 0.9823 | 1.0019 | Eukaryote | GH |
| CUPP | 0.9931 | 0.0268 | 0.9845 | 1.0016 | Eukaryote | GH |
| dbCAN_4 | 0.9900 | 0.0492 | 0.9790 | 1.0009 | All | GT |
| dbCAN_4:HMMER | 0.9904 | 0.0487 | 0.9796 | 1.0012 | All | GT |
| dbCAN_4:DIAMOND | 0.9893 | 0.0488 | 0.9785 | 1.0002 | All | GT |
| dbCAN_4:dbCAN-sub | 0.9900 | 0.0492 | 0.9790 | 1.0009 | All | GT |
| CUPP | 0.9921 | 0.0463 | 0.9818 | 1.0024 | All | GT |
| dbCAN_4 | 0.9987 | 0.0047 | 0.9972 | 1.0002 | Bacteria | GT |
| dbCAN_4:HMMER | 0.9990 | 0.0044 | 0.9976 | 1.0004 | Bacteria | GT |
| dbCAN_4:DIAMOND | 0.9983 | 0.0073 | 0.9959 | 1.0006 | Bacteria | GT |
| dbCAN_4:dbCAN-sub | 0.9987 | 0.0047 | 0.9972 | 1.0002 | Bacteria | GT |
| CUPP | 0.9994 | 0.0039 | 0.9982 | 1.0006 | Bacteria | GT |
| dbCAN_4 | 0.9812 | 0.0687 | 0.9592 | 1.0032 | Eukaryote | GT |
| dbCAN_4:HMMER | 0.9818 | 0.0680 | 0.9600 | 1.0035 | Eukaryote | GT |
| dbCAN_4:DIAMOND | 0.9804 | 0.0678 | 0.9587 | 1.0021 | Eukaryote | GT |
| dbCAN_4:dbCAN-sub | 0.9812 | 0.0687 | 0.9592 | 1.0032 | Eukaryote | GT |
| CUPP | 0.9848 | 0.0649 | 0.9640 | 1.0056 | Eukaryote | GT |
| dbCAN_4 | 0.9994 | 0.0025 | 0.9986 | 1.0001 | All | PL |
| dbCAN_4:HMMER | 0.9994 | 0.0025 | 0.9986 | 1.0001 | All | PL |
| dbCAN_4:DIAMOND | 0.9989 | 0.0039 | 0.9978 | 1.0000 | All | PL |
| dbCAN_4:dbCAN-sub | 0.9994 | 0.0025 | 0.9986 | 1.0001 | All | PL |
| CUPP | 0.9996 | 0.0019 | 0.9990 | 1.0002 | All | PL |
| dbCAN_4 | 0.9996 | 0.0021 | 0.9988 | 1.0004 | Bacteria | PL |
| dbCAN_4:HMMER | 0.9996 | 0.0021 | 0.9988 | 1.0004 | Bacteria | PL |
| dbCAN_4:DIAMOND | 0.9993 | 0.0028 | 0.9982 | 1.0003 | Bacteria | PL |
| dbCAN_4:dbCAN-sub | 0.9996 | 0.0021 | 0.9988 | 1.0004 | Bacteria | PL |
| CUPP | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | PL |
| dbCAN_4 | 0.9989 | 0.0030 | 0.9974 | 1.0005 | Eukaryote | PL |
| dbCAN_4:HMMER | 0.9989 | 0.0031 | 0.9973 | 1.0005 | Eukaryote | PL |
| dbCAN_4:DIAMOND | 0.9982 | 0.0053 | 0.9955 | 1.0010 | Eukaryote | PL |
| dbCAN_4:dbCAN-sub | 0.9989 | 0.0030 | 0.9974 | 1.0005 | Eukaryote | PL |
| CUPP | 0.9989 | 0.0031 | 0.9973 | 1.0005 | Eukaryote | PL |
| dbCAN_4 | 0.9953 | 0.0179 | 0.9912 | 0.9994 | All | CE |
| dbCAN_4:HMMER | 0.9953 | 0.0179 | 0.9912 | 0.9994 | All | CE |
| dbCAN_4:DIAMOND | 0.9931 | 0.0227 | 0.9879 | 0.9983 | All | CE |
| dbCAN_4:dbCAN-sub | 0.9952 | 0.0181 | 0.9911 | 0.9993 | All | CE |
| CUPP | 0.9955 | 0.0178 | 0.9914 | 0.9995 | All | CE |
| dbCAN_4 | 0.9919 | 0.0241 | 0.9842 | 0.9996 | Bacteria | CE |
| dbCAN_4:HMMER | 0.9919 | 0.0241 | 0.9842 | 0.9996 | Bacteria | CE |
| dbCAN_4:DIAMOND | 0.9904 | 0.0276 | 0.9816 | 0.9993 | Bacteria | CE |
| dbCAN_4:dbCAN-sub | 0.9919 | 0.0241 | 0.9842 | 0.9996 | Bacteria | CE |
| CUPP | 0.9919 | 0.0239 | 0.9843 | 0.9995 | Bacteria | CE |
| dbCAN_4 | 0.9991 | 0.0038 | 0.9978 | 1.0004 | Eukaryote | CE |
| dbCAN_4:HMMER | 0.9991 | 0.0039 | 0.9978 | 1.0004 | Eukaryote | CE |
| dbCAN_4:DIAMOND | 0.9960 | 0.0155 | 0.9908 | 1.0013 | Eukaryote | CE |
| dbCAN_4:dbCAN-sub | 0.9989 | 0.0054 | 0.9970 | 1.0007 | Eukaryote | CE |
| CUPP | 0.9994 | 0.0035 | 0.9982 | 1.0006 | Eukaryote | CE |
| dbCAN_4 | 0.9907 | 0.0201 | 0.9848 | 0.9965 | All | AA |
| dbCAN_4:HMMER | 0.9907 | 0.0202 | 0.9848 | 0.9965 | All | AA |
| dbCAN_4:DIAMOND | 0.9903 | 0.0219 | 0.9839 | 0.9966 | All | AA |
| dbCAN_4:dbCAN-sub | 0.9905 | 0.0202 | 0.9846 | 0.9963 | All | AA |
| CUPP | 0.9919 | 0.0175 | 0.9868 | 0.9970 | All | AA |
| dbCAN_4 | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_4:HMMER | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_4:DIAMOND | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_4:dbCAN-sub | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| CUPP | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_4 | 0.9879 | 0.0223 | 0.9805 | 0.9953 | Eukaryote | AA |
| dbCAN_4:HMMER | 0.9879 | 0.0223 | 0.9804 | 0.9953 | Eukaryote | AA |
| dbCAN_4:DIAMOND | 0.9874 | 0.0242 | 0.9793 | 0.9954 | Eukaryote | AA |
| dbCAN_4:dbCAN-sub | 0.9876 | 0.0223 | 0.9802 | 0.9951 | Eukaryote | AA |
| CUPP | 0.9895 | 0.0193 | 0.9831 | 0.9960 | Eukaryote | AA |
| dbCAN_4 | 0.9951 | 0.0103 | 0.9928 | 0.9974 | All | CBM |
| dbCAN_4:HMMER | 0.9958 | 0.0097 | 0.9937 | 0.9980 | All | CBM |
| dbCAN_4:DIAMOND | 0.9938 | 0.0146 | 0.9906 | 0.9970 | All | CBM |
| dbCAN_4:dbCAN-sub | 0.9927 | 0.0129 | 0.9898 | 0.9955 | All | CBM |
| CUPP | 1.0000 | 0.0000 | 1.0000 | 1.0000 | All | CBM |
| dbCAN_4 | 0.9953 | 0.0106 | 0.9920 | 0.9987 | Bacteria | CBM |
| dbCAN_4:HMMER | 0.9951 | 0.0106 | 0.9917 | 0.9985 | Bacteria | CBM |
| dbCAN_4:DIAMOND | 0.9937 | 0.0154 | 0.9887 | 0.9986 | Bacteria | CBM |
| dbCAN_4:dbCAN-sub | 0.9939 | 0.0113 | 0.9903 | 0.9975 | Bacteria | CBM |
| CUPP | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | CBM |
| dbCAN_4 | 0.9949 | 0.0102 | 0.9916 | 0.9982 | Eukaryote | CBM |
| dbCAN_4:HMMER | 0.9966 | 0.0087 | 0.9938 | 0.9993 | Eukaryote | CBM |
| dbCAN_4:DIAMOND | 0.9939 | 0.0139 | 0.9895 | 0.9984 | Eukaryote | CBM |
| dbCAN_4:dbCAN-sub | 0.9914 | 0.0144 | 0.9868 | 0.9961 | Eukaryote | CBM |
| CUPP | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Eukaryote | CBM |
8.2.1.1 Testing per CAZy class
For each CAZy class run a two-way ANOVA to determine if there statistically significant differences between the tools and taxonomic kingdoms.
## [1] "----------------------------------------------------"
## [1] "GH"
## Df Sum Sq Mean Sq F value Pr(>F)
## Tax_group 2 0.0005 0.0002304 0.398 0.6715
## Prediction_tool 4 0.0058 0.0014499 2.507 0.0408 *
## Tax_group:Prediction_tool 8 0.0004 0.0000440 0.076 0.9997
## Residuals 785 0.4540 0.0005783
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1
## [1] "----------------------------------------------------"
## [1] "GT"
## Df Sum Sq Mean Sq F value Pr(>F)
## Tax_group 2 0.0287 0.014341 6.170 0.00219 **
## Prediction_tool 4 0.0007 0.000175 0.075 0.98977
## Tax_group:Prediction_tool 8 0.0001 0.000018 0.008 1.00000
## Residuals 785 1.8246 0.002324
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1
## [1] "----------------------------------------------------"
## [1] "PL"
## Df Sum Sq Mean Sq F value Pr(>F)
## Tax_group 2 0.000037 1.870e-05 2.518 0.0817 .
## Prediction_tool 4 0.000024 6.065e-06 0.817 0.5150
## Tax_group:Prediction_tool 8 0.000002 2.520e-07 0.034 1.0000
## Residuals 455 0.003380 7.428e-06
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1
## [1] "----------------------------------------------------"
## [1] "CE"
## Df Sum Sq Mean Sq F value Pr(>F)
## Tax_group 2 0.00452 0.0022616 6.341 0.00186 **
## Prediction_tool 4 0.00061 0.0001528 0.428 0.78819
## Tax_group:Prediction_tool 8 0.00004 0.0000056 0.016 1.00000
## Residuals 745 0.26573 0.0003567
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1
## [1] "----------------------------------------------------"
## [1] "AA"
## Df Sum Sq Mean Sq F value Pr(>F)
## Tax_group 2 0.00605 0.0030245 7.706 0.00051 ***
## Prediction_tool 4 0.00016 0.0000410 0.104 0.98093
## Tax_group:Prediction_tool 8 0.00002 0.0000030 0.008 1.00000
## Residuals 465 0.18250 0.0003925
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1
## [1] "----------------------------------------------------"
## [1] "CBM"
## Df Sum Sq Mean Sq F value Pr(>F)
## Tax_group 2 0.00001 0.0000027 0.023 0.977
## Prediction_tool 4 0.00502 0.0012551 10.772 1.67e-08 ***
## Tax_group:Prediction_tool 8 0.00016 0.0000206 0.177 0.994
## Residuals 785 0.09146 0.0001165
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1
## [1] "Found pairs of statistically signficant different means for CBM"8.2.2 Sensitivity
| Prediction_tool | Mean | Standard Deviation | LowerCI | UpperCI | Tax_group | CAZy_class |
|---|---|---|---|---|---|---|
| dbCAN_4 | 0.9500 | 0.0802 | 0.9322 | 0.9679 | All | GH |
| dbCAN_4:HMMER | 0.9202 | 0.0828 | 0.9017 | 0.9386 | All | GH |
| dbCAN_4:DIAMOND | 0.9737 | 0.0763 | 0.9567 | 0.9906 | All | GH |
| dbCAN_4:dbCAN-sub | 0.9473 | 0.0789 | 0.9297 | 0.9648 | All | GH |
| CUPP | 0.9080 | 0.0675 | 0.8930 | 0.9230 | All | GH |
| dbCAN_4 | 0.9534 | 0.1089 | 0.9186 | 0.9882 | Bacteria | GH |
| dbCAN_4:HMMER | 0.9173 | 0.1116 | 0.8816 | 0.9530 | Bacteria | GH |
| dbCAN_4:DIAMOND | 0.9588 | 0.1047 | 0.9253 | 0.9923 | Bacteria | GH |
| dbCAN_4:dbCAN-sub | 0.9549 | 0.1056 | 0.9211 | 0.9887 | Bacteria | GH |
| CUPP | 0.9170 | 0.0792 | 0.8917 | 0.9423 | Bacteria | GH |
| dbCAN_4 | 0.9467 | 0.0341 | 0.9358 | 0.9576 | Eukaryote | GH |
| dbCAN_4:HMMER | 0.9230 | 0.0375 | 0.9110 | 0.9350 | Eukaryote | GH |
| dbCAN_4:DIAMOND | 0.9885 | 0.0193 | 0.9823 | 0.9947 | Eukaryote | GH |
| dbCAN_4:dbCAN-sub | 0.9396 | 0.0363 | 0.9280 | 0.9512 | Eukaryote | GH |
| CUPP | 0.8990 | 0.0527 | 0.8821 | 0.9159 | Eukaryote | GH |
| dbCAN_4 | 0.9578 | 0.0921 | 0.9373 | 0.9783 | All | GT |
| dbCAN_4:HMMER | 0.8657 | 0.1110 | 0.8410 | 0.8904 | All | GT |
| dbCAN_4:DIAMOND | 0.9751 | 0.0914 | 0.9548 | 0.9954 | All | GT |
| dbCAN_4:dbCAN-sub | 0.9538 | 0.0835 | 0.9352 | 0.9724 | All | GT |
| CUPP | 0.8536 | 0.1107 | 0.8289 | 0.8782 | All | GT |
| dbCAN_4 | 0.9448 | 0.1259 | 0.9046 | 0.9851 | Bacteria | GT |
| dbCAN_4:HMMER | 0.8493 | 0.1301 | 0.8077 | 0.8909 | Bacteria | GT |
| dbCAN_4:DIAMOND | 0.9546 | 0.1262 | 0.9142 | 0.9949 | Bacteria | GT |
| dbCAN_4:dbCAN-sub | 0.9445 | 0.1117 | 0.9088 | 0.9802 | Bacteria | GT |
| CUPP | 0.8754 | 0.1137 | 0.8391 | 0.9118 | Bacteria | GT |
| dbCAN_4 | 0.9708 | 0.0317 | 0.9607 | 0.9809 | Eukaryote | GT |
| dbCAN_4:HMMER | 0.8821 | 0.0866 | 0.8544 | 0.9098 | Eukaryote | GT |
| dbCAN_4:DIAMOND | 0.9956 | 0.0118 | 0.9919 | 0.9994 | Eukaryote | GT |
| dbCAN_4:dbCAN-sub | 0.9631 | 0.0384 | 0.9508 | 0.9754 | Eukaryote | GT |
| CUPP | 0.8317 | 0.1045 | 0.7983 | 0.8651 | Eukaryote | GT |
| dbCAN_4 | 0.9739 | 0.0982 | 0.9451 | 1.0028 | All | PL |
| dbCAN_4:HMMER | 0.9739 | 0.0982 | 0.9451 | 1.0028 | All | PL |
| dbCAN_4:DIAMOND | 0.9987 | 0.0086 | 0.9962 | 1.0013 | All | PL |
| dbCAN_4:dbCAN-sub | 0.9752 | 0.0982 | 0.9464 | 1.0040 | All | PL |
| CUPP | 0.8511 | 0.2593 | 0.7749 | 0.9272 | All | PL |
| dbCAN_4 | 0.9592 | 0.1211 | 0.9139 | 1.0044 | Bacteria | PL |
| dbCAN_4:HMMER | 0.9592 | 0.1211 | 0.9139 | 1.0044 | Bacteria | PL |
| dbCAN_4:DIAMOND | 0.9980 | 0.0107 | 0.9940 | 1.0020 | Bacteria | PL |
| dbCAN_4:dbCAN-sub | 0.9611 | 0.1213 | 0.9158 | 1.0064 | Bacteria | PL |
| CUPP | 0.8484 | 0.2520 | 0.7542 | 0.9425 | Bacteria | PL |
| dbCAN_4 | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Eukaryote | PL |
| dbCAN_4:HMMER | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Eukaryote | PL |
| dbCAN_4:DIAMOND | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Eukaryote | PL |
| dbCAN_4:dbCAN-sub | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Eukaryote | PL |
| CUPP | 0.8559 | 0.2794 | 0.7122 | 0.9996 | Eukaryote | PL |
| dbCAN_4 | 0.9783 | 0.0669 | 0.9630 | 0.9935 | All | CE |
| dbCAN_4:HMMER | 0.9529 | 0.1012 | 0.9298 | 0.9760 | All | CE |
| dbCAN_4:DIAMOND | 0.9755 | 0.0851 | 0.9560 | 0.9949 | All | CE |
| dbCAN_4:dbCAN-sub | 0.9755 | 0.0680 | 0.9599 | 0.9910 | All | CE |
| CUPP | 0.9114 | 0.1332 | 0.8810 | 0.9419 | All | CE |
| dbCAN_4 | 0.9670 | 0.0836 | 0.9403 | 0.9937 | Bacteria | CE |
| dbCAN_4:HMMER | 0.9245 | 0.1269 | 0.8839 | 0.9650 | Bacteria | CE |
| dbCAN_4:DIAMOND | 0.9618 | 0.1104 | 0.9265 | 0.9971 | Bacteria | CE |
| dbCAN_4:dbCAN-sub | 0.9634 | 0.0852 | 0.9362 | 0.9907 | Bacteria | CE |
| CUPP | 0.8983 | 0.1322 | 0.8560 | 0.9405 | Bacteria | CE |
| dbCAN_4 | 0.9907 | 0.0387 | 0.9776 | 1.0038 | Eukaryote | CE |
| dbCAN_4:HMMER | 0.9845 | 0.0455 | 0.9691 | 0.9999 | Eukaryote | CE |
| dbCAN_4:DIAMOND | 0.9907 | 0.0387 | 0.9776 | 1.0038 | Eukaryote | CE |
| dbCAN_4:dbCAN-sub | 0.9888 | 0.0383 | 0.9759 | 1.0018 | Eukaryote | CE |
| CUPP | 0.9260 | 0.1346 | 0.8805 | 0.9716 | Eukaryote | CE |
| dbCAN_4 | 0.9937 | 0.0258 | 0.9862 | 1.0012 | All | AA |
| dbCAN_4:HMMER | 0.9880 | 0.0393 | 0.9766 | 0.9994 | All | AA |
| dbCAN_4:DIAMOND | 0.9700 | 0.0952 | 0.9423 | 0.9976 | All | AA |
| dbCAN_4:dbCAN-sub | 0.9892 | 0.0331 | 0.9796 | 0.9988 | All | AA |
| CUPP | 0.9047 | 0.1300 | 0.8670 | 0.9425 | All | AA |
| dbCAN_4 | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_4:HMMER | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_4:DIAMOND | 0.9545 | 0.1508 | 0.8533 | 1.0558 | Bacteria | AA |
| dbCAN_4:dbCAN-sub | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| CUPP | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_4 | 0.9918 | 0.0292 | 0.9821 | 1.0016 | Eukaryote | AA |
| dbCAN_4:HMMER | 0.9844 | 0.0442 | 0.9697 | 0.9992 | Eukaryote | AA |
| dbCAN_4:DIAMOND | 0.9746 | 0.0737 | 0.9500 | 0.9992 | Eukaryote | AA |
| dbCAN_4:dbCAN-sub | 0.9860 | 0.0372 | 0.9736 | 0.9984 | Eukaryote | AA |
| CUPP | 0.8764 | 0.1359 | 0.8311 | 0.9217 | Eukaryote | AA |
| dbCAN_4 | 0.7995 | 0.1921 | 0.7567 | 0.8422 | All | CBM |
| dbCAN_4:HMMER | 0.4740 | 0.2360 | 0.4215 | 0.5266 | All | CBM |
| dbCAN_4:DIAMOND | 0.8773 | 0.1695 | 0.8396 | 0.9151 | All | CBM |
| dbCAN_4:dbCAN-sub | 0.8193 | 0.1995 | 0.7749 | 0.8637 | All | CBM |
| CUPP | 0.0000 | 0.0000 | 0.0000 | 0.0000 | All | CBM |
| dbCAN_4 | 0.9025 | 0.1017 | 0.8699 | 0.9350 | Bacteria | CBM |
| dbCAN_4:HMMER | 0.6086 | 0.2286 | 0.5355 | 0.6817 | Bacteria | CBM |
| dbCAN_4:DIAMOND | 0.7955 | 0.1993 | 0.7318 | 0.8592 | Bacteria | CBM |
| dbCAN_4:dbCAN-sub | 0.9441 | 0.0985 | 0.9126 | 0.9756 | Bacteria | CBM |
| CUPP | 0.0000 | 0.0000 | 0.0000 | 0.0000 | Bacteria | CBM |
| dbCAN_4 | 0.6965 | 0.2066 | 0.6305 | 0.7626 | Eukaryote | CBM |
| dbCAN_4:HMMER | 0.3395 | 0.1530 | 0.2906 | 0.3884 | Eukaryote | CBM |
| dbCAN_4:DIAMOND | 0.9592 | 0.0692 | 0.9370 | 0.9813 | Eukaryote | CBM |
| dbCAN_4:dbCAN-sub | 0.6945 | 0.1974 | 0.6314 | 0.7577 | Eukaryote | CBM |
| CUPP | 0.0000 | 0.0000 | 0.0000 | 0.0000 | Eukaryote | CBM |
8.2.2.1 Testing per CAZy class
For each CAZy class run a two-way ANOVA to determine if there statistically significant differences between the tools and taxonomic kingdoms.
## [1] "Found pairs of statistically signficant different means for GH"
## [1] "Found pairs of statistically signficant different means for GT"
## [1] "Found pairs of statistically signficant different means for PL"
## [1] "Found pairs of statistically signficant different means for CE"
## [1] "Found pairs of statistically signficant different means for AA"
## [1] "Found pairs of statistically signficant different means for CBM"8.2.3 Precision
| Prediction_tool | Mean | Standard Deviation | LowerCI | UpperCI | Tax_group | CAZy_class |
|---|---|---|---|---|---|---|
| dbCAN_4 | 0.9898 | 0.0337 | 0.9823 | 0.9973 | All | GH |
| dbCAN_4:HMMER | 0.9909 | 0.0330 | 0.9836 | 0.9983 | All | GH |
| dbCAN_4:DIAMOND | 0.9842 | 0.0393 | 0.9754 | 0.9929 | All | GH |
| dbCAN_4:dbCAN-sub | 0.9896 | 0.0337 | 0.9821 | 0.9971 | All | GH |
| CUPP | 0.9906 | 0.0338 | 0.9831 | 0.9981 | All | GH |
| dbCAN_4 | 0.9923 | 0.0176 | 0.9867 | 0.9980 | Bacteria | GH |
| dbCAN_4:HMMER | 0.9945 | 0.0142 | 0.9900 | 0.9991 | Bacteria | GH |
| dbCAN_4:DIAMOND | 0.9886 | 0.0244 | 0.9808 | 0.9964 | Bacteria | GH |
| dbCAN_4:dbCAN-sub | 0.9920 | 0.0175 | 0.9864 | 0.9976 | Bacteria | GH |
| CUPP | 0.9931 | 0.0143 | 0.9886 | 0.9977 | Bacteria | GH |
| dbCAN_4 | 0.9873 | 0.0445 | 0.9730 | 1.0015 | Eukaryote | GH |
| dbCAN_4:HMMER | 0.9873 | 0.0444 | 0.9731 | 1.0015 | Eukaryote | GH |
| dbCAN_4:DIAMOND | 0.9797 | 0.0499 | 0.9638 | 0.9957 | Eukaryote | GH |
| dbCAN_4:dbCAN-sub | 0.9872 | 0.0445 | 0.9730 | 1.0015 | Eukaryote | GH |
| CUPP | 0.9880 | 0.0458 | 0.9734 | 1.0027 | Eukaryote | GH |
| dbCAN_4 | 0.9866 | 0.0566 | 0.9740 | 0.9992 | All | GT |
| dbCAN_4:HMMER | 0.9884 | 0.0566 | 0.9758 | 1.0010 | All | GT |
| dbCAN_4:DIAMOND | 0.9841 | 0.0638 | 0.9699 | 0.9983 | All | GT |
| dbCAN_4:dbCAN-sub | 0.9866 | 0.0566 | 0.9740 | 0.9992 | All | GT |
| CUPP | 0.9883 | 0.0625 | 0.9744 | 1.0022 | All | GT |
| dbCAN_4 | 0.9980 | 0.0074 | 0.9957 | 1.0004 | Bacteria | GT |
| dbCAN_4:HMMER | 0.9988 | 0.0054 | 0.9971 | 1.0005 | Bacteria | GT |
| dbCAN_4:DIAMOND | 0.9975 | 0.0091 | 0.9945 | 1.0004 | Bacteria | GT |
| dbCAN_4:dbCAN-sub | 0.9980 | 0.0074 | 0.9957 | 1.0004 | Bacteria | GT |
| CUPP | 0.9995 | 0.0030 | 0.9985 | 1.0005 | Bacteria | GT |
| dbCAN_4 | 0.9752 | 0.0785 | 0.9501 | 1.0003 | Eukaryote | GT |
| dbCAN_4:HMMER | 0.9781 | 0.0790 | 0.9528 | 1.0033 | Eukaryote | GT |
| dbCAN_4:DIAMOND | 0.9707 | 0.0883 | 0.9425 | 0.9990 | Eukaryote | GT |
| dbCAN_4:dbCAN-sub | 0.9752 | 0.0785 | 0.9501 | 1.0003 | Eukaryote | GT |
| CUPP | 0.9771 | 0.0874 | 0.9491 | 1.0050 | Eukaryote | GT |
| dbCAN_4 | 0.9846 | 0.0766 | 0.9621 | 1.0071 | All | PL |
| dbCAN_4:HMMER | 0.9846 | 0.0766 | 0.9621 | 1.0071 | All | PL |
| dbCAN_4:DIAMOND | 0.9730 | 0.1012 | 0.9433 | 1.0028 | All | PL |
| dbCAN_4:dbCAN-sub | 0.9846 | 0.0766 | 0.9621 | 1.0071 | All | PL |
| CUPP | 0.9496 | 0.2058 | 0.8892 | 1.0101 | All | PL |
| dbCAN_4 | 0.9980 | 0.0107 | 0.9940 | 1.0020 | Bacteria | PL |
| dbCAN_4:HMMER | 0.9980 | 0.0107 | 0.9940 | 1.0020 | Bacteria | PL |
| dbCAN_4:DIAMOND | 0.9869 | 0.0614 | 0.9640 | 1.0099 | Bacteria | PL |
| dbCAN_4:dbCAN-sub | 0.9980 | 0.0107 | 0.9940 | 1.0020 | Bacteria | PL |
| CUPP | 0.9667 | 0.1826 | 0.8985 | 1.0348 | Bacteria | PL |
| dbCAN_4 | 0.9608 | 0.1254 | 0.8963 | 1.0253 | Eukaryote | PL |
| dbCAN_4:HMMER | 0.9608 | 0.1254 | 0.8963 | 1.0253 | Eukaryote | PL |
| dbCAN_4:DIAMOND | 0.9485 | 0.1470 | 0.8730 | 1.0241 | Eukaryote | PL |
| dbCAN_4:dbCAN-sub | 0.9608 | 0.1254 | 0.8963 | 1.0253 | Eukaryote | PL |
| CUPP | 0.9196 | 0.2447 | 0.7938 | 1.0454 | Eukaryote | PL |
| dbCAN_4 | 0.9603 | 0.1103 | 0.9351 | 0.9855 | All | CE |
| dbCAN_4:HMMER | 0.9603 | 0.1103 | 0.9351 | 0.9855 | All | CE |
| dbCAN_4:DIAMOND | 0.9476 | 0.1506 | 0.9132 | 0.9820 | All | CE |
| dbCAN_4:dbCAN-sub | 0.9592 | 0.1120 | 0.9336 | 0.9848 | All | CE |
| CUPP | 0.9598 | 0.1130 | 0.9339 | 0.9856 | All | CE |
| dbCAN_4 | 0.9324 | 0.1429 | 0.8867 | 0.9781 | Bacteria | CE |
| dbCAN_4:HMMER | 0.9324 | 0.1429 | 0.8867 | 0.9781 | Bacteria | CE |
| dbCAN_4:DIAMOND | 0.9295 | 0.1739 | 0.8739 | 0.9851 | Bacteria | CE |
| dbCAN_4:dbCAN-sub | 0.9321 | 0.1429 | 0.8864 | 0.9778 | Bacteria | CE |
| CUPP | 0.9298 | 0.1452 | 0.8834 | 0.9762 | Bacteria | CE |
| dbCAN_4 | 0.9914 | 0.0377 | 0.9786 | 1.0041 | Eukaryote | CE |
| dbCAN_4:HMMER | 0.9914 | 0.0377 | 0.9786 | 1.0041 | Eukaryote | CE |
| dbCAN_4:DIAMOND | 0.9677 | 0.1189 | 0.9275 | 1.0079 | Eukaryote | CE |
| dbCAN_4:dbCAN-sub | 0.9893 | 0.0486 | 0.9729 | 1.0058 | Eukaryote | CE |
| CUPP | 0.9931 | 0.0417 | 0.9790 | 1.0072 | Eukaryote | CE |
| dbCAN_4 | 0.9198 | 0.1610 | 0.8731 | 0.9666 | All | AA |
| dbCAN_4:HMMER | 0.9192 | 0.1624 | 0.8720 | 0.9664 | All | AA |
| dbCAN_4:DIAMOND | 0.9196 | 0.1697 | 0.8703 | 0.9689 | All | AA |
| dbCAN_4:dbCAN-sub | 0.9177 | 0.1620 | 0.8707 | 0.9648 | All | AA |
| CUPP | 0.9184 | 0.1697 | 0.8691 | 0.9677 | All | AA |
| dbCAN_4 | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_4:HMMER | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_4:DIAMOND | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_4:dbCAN-sub | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| CUPP | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_4 | 0.8960 | 0.1769 | 0.8370 | 0.9550 | Eukaryote | AA |
| dbCAN_4:HMMER | 0.8952 | 0.1785 | 0.8357 | 0.9547 | Eukaryote | AA |
| dbCAN_4:DIAMOND | 0.8957 | 0.1872 | 0.8333 | 0.9581 | Eukaryote | AA |
| dbCAN_4:dbCAN-sub | 0.8932 | 0.1777 | 0.8340 | 0.9525 | Eukaryote | AA |
| CUPP | 0.8942 | 0.1870 | 0.8318 | 0.9565 | Eukaryote | AA |
| dbCAN_4 | 0.9562 | 0.0919 | 0.9358 | 0.9767 | All | CBM |
| dbCAN_4:HMMER | 0.9184 | 0.1999 | 0.8739 | 0.9629 | All | CBM |
| dbCAN_4:DIAMOND | 0.9571 | 0.1273 | 0.9288 | 0.9854 | All | CBM |
| dbCAN_4:dbCAN-sub | 0.9376 | 0.1151 | 0.9120 | 0.9632 | All | CBM |
| CUPP | 0.0000 | 0.0000 | 0.0000 | 0.0000 | All | CBM |
| dbCAN_4 | 0.9699 | 0.0662 | 0.9487 | 0.9911 | Bacteria | CBM |
| dbCAN_4:HMMER | 0.9524 | 0.1130 | 0.9163 | 0.9886 | Bacteria | CBM |
| dbCAN_4:DIAMOND | 0.9604 | 0.1591 | 0.9095 | 1.0113 | Bacteria | CBM |
| dbCAN_4:dbCAN-sub | 0.9624 | 0.0681 | 0.9406 | 0.9842 | Bacteria | CBM |
| CUPP | 0.0000 | 0.0000 | 0.0000 | 0.0000 | Bacteria | CBM |
| dbCAN_4 | 0.9426 | 0.1111 | 0.9071 | 0.9781 | Eukaryote | CBM |
| dbCAN_4:HMMER | 0.8844 | 0.2565 | 0.8023 | 0.9664 | Eukaryote | CBM |
| dbCAN_4:DIAMOND | 0.9538 | 0.0865 | 0.9261 | 0.9815 | Eukaryote | CBM |
| dbCAN_4:dbCAN-sub | 0.9128 | 0.1447 | 0.8665 | 0.9591 | Eukaryote | CBM |
| CUPP | 0.0000 | 0.0000 | 0.0000 | 0.0000 | Eukaryote | CBM |
8.2.3.1 Testing per CAZy class
For each CAZy class run a two-way ANOVA to determine if there statistically significant differences between the tools and taxonomic kingdoms.
## [1] "Found pairs of statistically signficant different means for CBM"8.2.4 F1-score
| Prediction_tool | Mean | Standard Deviation | LowerCI | UpperCI | Tax_group | CAZy_class |
|---|---|---|---|---|---|---|
| dbCAN_4 | 0.9671 | 0.0590 | 0.9539 | 0.9802 | All | GH |
| dbCAN_4:HMMER | 0.9516 | 0.0596 | 0.9384 | 0.9649 | All | GH |
| dbCAN_4:DIAMOND | 0.9764 | 0.0583 | 0.9634 | 0.9894 | All | GH |
| dbCAN_4:dbCAN-sub | 0.9655 | 0.0581 | 0.9526 | 0.9785 | All | GH |
| CUPP | 0.9461 | 0.0454 | 0.9360 | 0.9562 | All | GH |
| dbCAN_4 | 0.9682 | 0.0776 | 0.9434 | 0.9930 | Bacteria | GH |
| dbCAN_4:HMMER | 0.9499 | 0.0782 | 0.9249 | 0.9749 | Bacteria | GH |
| dbCAN_4:DIAMOND | 0.9694 | 0.0764 | 0.9449 | 0.9938 | Bacteria | GH |
| dbCAN_4:dbCAN-sub | 0.9690 | 0.0761 | 0.9447 | 0.9933 | Bacteria | GH |
| CUPP | 0.9516 | 0.0487 | 0.9360 | 0.9672 | Bacteria | GH |
| dbCAN_4 | 0.9659 | 0.0319 | 0.9557 | 0.9761 | Eukaryote | GH |
| dbCAN_4:HMMER | 0.9534 | 0.0329 | 0.9429 | 0.9639 | Eukaryote | GH |
| dbCAN_4:DIAMOND | 0.9834 | 0.0307 | 0.9736 | 0.9932 | Eukaryote | GH |
| dbCAN_4:dbCAN-sub | 0.9621 | 0.0320 | 0.9519 | 0.9723 | Eukaryote | GH |
| CUPP | 0.9405 | 0.0416 | 0.9272 | 0.9538 | Eukaryote | GH |
| dbCAN_4 | 0.9677 | 0.0753 | 0.9510 | 0.9845 | All | GT |
| dbCAN_4:HMMER | 0.9170 | 0.0838 | 0.8984 | 0.9357 | All | GT |
| dbCAN_4:DIAMOND | 0.9750 | 0.0781 | 0.9577 | 0.9924 | All | GT |
| dbCAN_4:dbCAN-sub | 0.9664 | 0.0656 | 0.9518 | 0.9810 | All | GT |
| CUPP | 0.9107 | 0.0758 | 0.8938 | 0.9276 | All | GT |
| dbCAN_4 | 0.9647 | 0.0958 | 0.9340 | 0.9953 | Bacteria | GT |
| dbCAN_4:HMMER | 0.9112 | 0.1007 | 0.8790 | 0.9434 | Bacteria | GT |
| dbCAN_4:DIAMOND | 0.9695 | 0.0962 | 0.9387 | 1.0003 | Bacteria | GT |
| dbCAN_4:dbCAN-sub | 0.9660 | 0.0801 | 0.9404 | 0.9917 | Bacteria | GT |
| CUPP | 0.9292 | 0.0713 | 0.9064 | 0.9520 | Bacteria | GT |
| dbCAN_4 | 0.9708 | 0.0479 | 0.9555 | 0.9861 | Eukaryote | GT |
| dbCAN_4:HMMER | 0.9229 | 0.0634 | 0.9026 | 0.9432 | Eukaryote | GT |
| dbCAN_4:DIAMOND | 0.9806 | 0.0551 | 0.9630 | 0.9982 | Eukaryote | GT |
| dbCAN_4:dbCAN-sub | 0.9667 | 0.0481 | 0.9513 | 0.9821 | Eukaryote | GT |
| CUPP | 0.8923 | 0.0766 | 0.8678 | 0.9168 | Eukaryote | GT |
| dbCAN_4 | 0.9741 | 0.0781 | 0.9511 | 0.9970 | All | PL |
| dbCAN_4:HMMER | 0.9741 | 0.0781 | 0.9511 | 0.9970 | All | PL |
| dbCAN_4:DIAMOND | 0.9825 | 0.0646 | 0.9635 | 1.0014 | All | PL |
| dbCAN_4:dbCAN-sub | 0.9747 | 0.0782 | 0.9518 | 0.9977 | All | PL |
| CUPP | 0.8850 | 0.2288 | 0.8178 | 0.9522 | All | PL |
| dbCAN_4 | 0.9735 | 0.0770 | 0.9448 | 1.0023 | Bacteria | PL |
| dbCAN_4:HMMER | 0.9735 | 0.0770 | 0.9448 | 1.0023 | Bacteria | PL |
| dbCAN_4:DIAMOND | 0.9913 | 0.0369 | 0.9775 | 1.0051 | Bacteria | PL |
| dbCAN_4:dbCAN-sub | 0.9745 | 0.0771 | 0.9457 | 1.0034 | Bacteria | PL |
| CUPP | 0.8899 | 0.2178 | 0.8085 | 0.9712 | Bacteria | PL |
| dbCAN_4 | 0.9750 | 0.0825 | 0.9326 | 1.0174 | Eukaryote | PL |
| dbCAN_4:HMMER | 0.9750 | 0.0825 | 0.9326 | 1.0174 | Eukaryote | PL |
| dbCAN_4:DIAMOND | 0.9668 | 0.0954 | 0.9178 | 1.0159 | Eukaryote | PL |
| dbCAN_4:dbCAN-sub | 0.9750 | 0.0825 | 0.9326 | 1.0174 | Eukaryote | PL |
| CUPP | 0.8764 | 0.2539 | 0.7459 | 1.0070 | Eukaryote | PL |
| dbCAN_4 | 0.9638 | 0.0854 | 0.9443 | 0.9833 | All | CE |
| dbCAN_4:HMMER | 0.9487 | 0.0957 | 0.9268 | 0.9706 | All | CE |
| dbCAN_4:DIAMOND | 0.9507 | 0.1192 | 0.9234 | 0.9779 | All | CE |
| dbCAN_4:dbCAN-sub | 0.9617 | 0.0863 | 0.9420 | 0.9814 | All | CE |
| CUPP | 0.9250 | 0.1095 | 0.9000 | 0.9500 | All | CE |
| dbCAN_4 | 0.9400 | 0.1099 | 0.9049 | 0.9751 | Bacteria | CE |
| dbCAN_4:HMMER | 0.9143 | 0.1191 | 0.8762 | 0.9524 | Bacteria | CE |
| dbCAN_4:DIAMOND | 0.9299 | 0.1425 | 0.8843 | 0.9754 | Bacteria | CE |
| dbCAN_4:dbCAN-sub | 0.9381 | 0.1101 | 0.9029 | 0.9733 | Bacteria | CE |
| CUPP | 0.9000 | 0.1196 | 0.8617 | 0.9382 | Bacteria | CE |
| dbCAN_4 | 0.9902 | 0.0287 | 0.9805 | 1.0000 | Eukaryote | CE |
| dbCAN_4:HMMER | 0.9869 | 0.0309 | 0.9765 | 0.9974 | Eukaryote | CE |
| dbCAN_4:DIAMOND | 0.9738 | 0.0823 | 0.9459 | 1.0016 | Eukaryote | CE |
| dbCAN_4:dbCAN-sub | 0.9880 | 0.0335 | 0.9766 | 0.9993 | Eukaryote | CE |
| CUPP | 0.9528 | 0.0907 | 0.9221 | 0.9835 | Eukaryote | CE |
| dbCAN_4 | 0.9464 | 0.1085 | 0.9149 | 0.9779 | All | AA |
| dbCAN_4:HMMER | 0.9434 | 0.1112 | 0.9111 | 0.9757 | All | AA |
| dbCAN_4:DIAMOND | 0.9306 | 0.1226 | 0.8950 | 0.9662 | All | AA |
| dbCAN_4:dbCAN-sub | 0.9430 | 0.1090 | 0.9113 | 0.9746 | All | AA |
| CUPP | 0.9011 | 0.1376 | 0.8611 | 0.9410 | All | AA |
| dbCAN_4 | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_4:HMMER | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_4:DIAMOND | 0.9697 | 0.1005 | 0.9022 | 1.0372 | Bacteria | AA |
| dbCAN_4:dbCAN-sub | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| CUPP | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_4 | 0.9305 | 0.1193 | 0.8907 | 0.9703 | Eukaryote | AA |
| dbCAN_4:HMMER | 0.9266 | 0.1219 | 0.8860 | 0.9673 | Eukaryote | AA |
| dbCAN_4:DIAMOND | 0.9190 | 0.1274 | 0.8765 | 0.9615 | Eukaryote | AA |
| dbCAN_4:dbCAN-sub | 0.9260 | 0.1193 | 0.8863 | 0.9658 | Eukaryote | AA |
| CUPP | 0.8716 | 0.1443 | 0.8235 | 0.9197 | Eukaryote | AA |
| dbCAN_4 | 0.8547 | 0.1392 | 0.8237 | 0.8857 | All | CBM |
| dbCAN_4:HMMER | 0.5954 | 0.2202 | 0.5464 | 0.6444 | All | CBM |
| dbCAN_4:DIAMOND | 0.9072 | 0.1362 | 0.8768 | 0.9375 | All | CBM |
| dbCAN_4:dbCAN-sub | 0.8576 | 0.1492 | 0.8244 | 0.8908 | All | CBM |
| CUPP | 0.0000 | 0.0000 | 0.0000 | 0.0000 | All | CBM |
| dbCAN_4 | 0.9296 | 0.0604 | 0.9103 | 0.9489 | Bacteria | CBM |
| dbCAN_4:HMMER | 0.7163 | 0.1850 | 0.6571 | 0.7755 | Bacteria | CBM |
| dbCAN_4:DIAMOND | 0.8607 | 0.1698 | 0.8063 | 0.9150 | Bacteria | CBM |
| dbCAN_4:dbCAN-sub | 0.9484 | 0.0628 | 0.9283 | 0.9685 | Bacteria | CBM |
| CUPP | 0.0000 | 0.0000 | 0.0000 | 0.0000 | Bacteria | CBM |
| dbCAN_4 | 0.7798 | 0.1552 | 0.7302 | 0.8295 | Eukaryote | CBM |
| dbCAN_4:HMMER | 0.4745 | 0.1843 | 0.4155 | 0.5334 | Eukaryote | CBM |
| dbCAN_4:DIAMOND | 0.9537 | 0.0657 | 0.9327 | 0.9747 | Eukaryote | CBM |
| dbCAN_4:dbCAN-sub | 0.7669 | 0.1557 | 0.7171 | 0.8166 | Eukaryote | CBM |
| CUPP | 0.0000 | 0.0000 | 0.0000 | 0.0000 | Eukaryote | CBM |
8.2.4.1 Testing per CAZy class
For each CAZy class run a two-way ANOVA to determine if there statistically significant differences between the tools and taxonomic kingdoms.
## [1] "----------------------------------------------------"
## [1] "GH"
## Df Sum Sq Mean Sq F value Pr(>F)
## Tax_group 2 0.0000 0.000015 0.005 0.995
## Prediction_tool 4 0.0967 0.024175 7.598 5.24e-06 ***
## Tax_group:Prediction_tool 8 0.0077 0.000961 0.302 0.965
## Residuals 785 2.4979 0.003182
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1
## [1] "Found pairs of statistically signficant different means for GH"
## [1] "----------------------------------------------------"
## [1] "GT"
## Df Sum Sq Mean Sq F value Pr(>F)
## Tax_group 2 0.000 0.00011 0.019 0.981
## Prediction_tool 4 0.609 0.15221 26.408 <2e-16 ***
## Tax_group:Prediction_tool 8 0.033 0.00412 0.715 0.679
## Residuals 785 4.525 0.00576
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1
## [1] "Found pairs of statistically signficant different means for GT"
## [1] "----------------------------------------------------"
## [1] "PL"
## Df Sum Sq Mean Sq F value Pr(>F)
## Tax_group 2 0.003 0.00128 0.085 0.919
## Prediction_tool 4 0.632 0.15795 10.448 4.19e-08 ***
## Tax_group:Prediction_tool 8 0.006 0.00074 0.049 1.000
## Residuals 455 6.879 0.01512
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1
## [1] "Found pairs of statistically signficant different means for PL"
## [1] "----------------------------------------------------"
## [1] "CE"
## Df Sum Sq Mean Sq F value Pr(>F)
## Tax_group 2 0.275 0.13765 14.185 8.99e-07 ***
## Prediction_tool 4 0.145 0.03624 3.734 0.00511 **
## Tax_group:Prediction_tool 8 0.009 0.00114 0.117 0.99860
## Residuals 745 7.230 0.00970
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1
## [1] "Found pairs of statistically signficant different means for CE"
## [1] "----------------------------------------------------"
## [1] "AA"
## Df Sum Sq Mean Sq F value Pr(>F)
## Tax_group 2 0.266 0.13290 9.835 6.55e-05 ***
## Prediction_tool 4 0.136 0.03396 2.513 0.041 *
## Tax_group:Prediction_tool 8 0.029 0.00359 0.266 0.977
## Residuals 465 6.284 0.01351
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1
## [1] "----------------------------------------------------"
## [1] "CBM"
## Df Sum Sq Mean Sq F value Pr(>F)
## Tax_group 2 0.92 0.461 24.59 4.37e-11 ***
## Prediction_tool 4 92.22 23.056 1229.62 < 2e-16 ***
## Tax_group:Prediction_tool 8 1.53 0.191 10.19 1.33e-13 ***
## Residuals 785 14.72 0.019
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1
## [1] "Found pairs of statistically signficant different means for CBM"8.2.5 Accuracy
| Prediction_tool | Mean | Standard Deviation | LowerCI | UpperCI | Tax_group | CAZy_class |
|---|---|---|---|---|---|---|
| dbCAN_4 | 0.9743 | 0.0307 | 0.9675 | 0.9812 | All | GH |
| dbCAN_4:HMMER | 0.9601 | 0.0328 | 0.9528 | 0.9674 | All | GH |
| dbCAN_4:DIAMOND | 0.9812 | 0.0304 | 0.9745 | 0.9880 | All | GH |
| dbCAN_4:dbCAN-sub | 0.9731 | 0.0297 | 0.9665 | 0.9797 | All | GH |
| CUPP | 0.9540 | 0.0293 | 0.9475 | 0.9605 | All | GH |
| dbCAN_4 | 0.9762 | 0.0378 | 0.9641 | 0.9883 | Bacteria | GH |
| dbCAN_4:HMMER | 0.9584 | 0.0405 | 0.9454 | 0.9713 | Bacteria | GH |
| dbCAN_4:DIAMOND | 0.9766 | 0.0361 | 0.9650 | 0.9881 | Bacteria | GH |
| dbCAN_4:dbCAN-sub | 0.9765 | 0.0361 | 0.9649 | 0.9880 | Bacteria | GH |
| CUPP | 0.9555 | 0.0313 | 0.9455 | 0.9655 | Bacteria | GH |
| dbCAN_4 | 0.9725 | 0.0218 | 0.9655 | 0.9795 | Eukaryote | GH |
| dbCAN_4:HMMER | 0.9619 | 0.0231 | 0.9545 | 0.9692 | Eukaryote | GH |
| dbCAN_4:DIAMOND | 0.9859 | 0.0230 | 0.9785 | 0.9933 | Eukaryote | GH |
| dbCAN_4:dbCAN-sub | 0.9698 | 0.0215 | 0.9630 | 0.9767 | Eukaryote | GH |
| CUPP | 0.9525 | 0.0275 | 0.9437 | 0.9613 | Eukaryote | GH |
| dbCAN_4 | 0.9781 | 0.0572 | 0.9654 | 0.9909 | All | GT |
| dbCAN_4:HMMER | 0.9503 | 0.0597 | 0.9370 | 0.9635 | All | GT |
| dbCAN_4:DIAMOND | 0.9838 | 0.0577 | 0.9710 | 0.9966 | All | GT |
| dbCAN_4:dbCAN-sub | 0.9773 | 0.0519 | 0.9657 | 0.9889 | All | GT |
| CUPP | 0.9462 | 0.0579 | 0.9333 | 0.9591 | All | GT |
| dbCAN_4 | 0.9764 | 0.0732 | 0.9530 | 0.9998 | Bacteria | GT |
| dbCAN_4:HMMER | 0.9466 | 0.0753 | 0.9225 | 0.9706 | Bacteria | GT |
| dbCAN_4:DIAMOND | 0.9797 | 0.0738 | 0.9561 | 1.0033 | Bacteria | GT |
| dbCAN_4:dbCAN-sub | 0.9770 | 0.0650 | 0.9562 | 0.9978 | Bacteria | GT |
| CUPP | 0.9602 | 0.0488 | 0.9445 | 0.9758 | Bacteria | GT |
| dbCAN_4 | 0.9798 | 0.0354 | 0.9685 | 0.9911 | Eukaryote | GT |
| dbCAN_4:HMMER | 0.9540 | 0.0389 | 0.9415 | 0.9664 | Eukaryote | GT |
| dbCAN_4:DIAMOND | 0.9879 | 0.0354 | 0.9766 | 0.9992 | Eukaryote | GT |
| dbCAN_4:dbCAN-sub | 0.9776 | 0.0352 | 0.9664 | 0.9889 | Eukaryote | GT |
| CUPP | 0.9322 | 0.0633 | 0.9120 | 0.9525 | Eukaryote | GT |
| dbCAN_4 | 0.9986 | 0.0035 | 0.9975 | 0.9996 | All | PL |
| dbCAN_4:HMMER | 0.9986 | 0.0035 | 0.9975 | 0.9996 | All | PL |
| dbCAN_4:DIAMOND | 0.9988 | 0.0039 | 0.9976 | 0.9999 | All | PL |
| dbCAN_4:dbCAN-sub | 0.9988 | 0.0032 | 0.9978 | 0.9997 | All | PL |
| CUPP | 0.9941 | 0.0096 | 0.9913 | 0.9970 | All | PL |
| dbCAN_4 | 0.9983 | 0.0038 | 0.9969 | 0.9997 | Bacteria | PL |
| dbCAN_4:HMMER | 0.9983 | 0.0038 | 0.9969 | 0.9997 | Bacteria | PL |
| dbCAN_4:DIAMOND | 0.9990 | 0.0030 | 0.9979 | 1.0001 | Bacteria | PL |
| dbCAN_4:dbCAN-sub | 0.9987 | 0.0034 | 0.9974 | 1.0000 | Bacteria | PL |
| CUPP | 0.9930 | 0.0112 | 0.9888 | 0.9972 | Bacteria | PL |
| dbCAN_4 | 0.9990 | 0.0029 | 0.9974 | 1.0005 | Eukaryote | PL |
| dbCAN_4:HMMER | 0.9989 | 0.0030 | 0.9974 | 1.0005 | Eukaryote | PL |
| dbCAN_4:DIAMOND | 0.9983 | 0.0052 | 0.9956 | 1.0010 | Eukaryote | PL |
| dbCAN_4:dbCAN-sub | 0.9990 | 0.0029 | 0.9975 | 1.0005 | Eukaryote | PL |
| CUPP | 0.9961 | 0.0056 | 0.9933 | 0.9990 | Eukaryote | PL |
| dbCAN_4 | 0.9943 | 0.0172 | 0.9904 | 0.9982 | All | CE |
| dbCAN_4:HMMER | 0.9929 | 0.0173 | 0.9889 | 0.9968 | All | CE |
| dbCAN_4:DIAMOND | 0.9919 | 0.0218 | 0.9870 | 0.9969 | All | CE |
| dbCAN_4:dbCAN-sub | 0.9938 | 0.0175 | 0.9898 | 0.9978 | All | CE |
| CUPP | 0.9900 | 0.0187 | 0.9857 | 0.9943 | All | CE |
| dbCAN_4 | 0.9904 | 0.0228 | 0.9831 | 0.9977 | Bacteria | CE |
| dbCAN_4:HMMER | 0.9882 | 0.0225 | 0.9810 | 0.9954 | Bacteria | CE |
| dbCAN_4:DIAMOND | 0.9886 | 0.0263 | 0.9801 | 0.9970 | Bacteria | CE |
| dbCAN_4:dbCAN-sub | 0.9899 | 0.0230 | 0.9826 | 0.9973 | Bacteria | CE |
| CUPP | 0.9852 | 0.0236 | 0.9777 | 0.9927 | Bacteria | CE |
| dbCAN_4 | 0.9986 | 0.0041 | 0.9972 | 1.0000 | Eukaryote | CE |
| dbCAN_4:HMMER | 0.9981 | 0.0046 | 0.9965 | 0.9996 | Eukaryote | CE |
| dbCAN_4:DIAMOND | 0.9957 | 0.0147 | 0.9907 | 1.0007 | Eukaryote | CE |
| dbCAN_4:dbCAN-sub | 0.9981 | 0.0055 | 0.9963 | 1.0000 | Eukaryote | CE |
| CUPP | 0.9953 | 0.0086 | 0.9924 | 0.9983 | Eukaryote | CE |
| dbCAN_4 | 0.9907 | 0.0188 | 0.9853 | 0.9962 | All | AA |
| dbCAN_4:HMMER | 0.9901 | 0.0196 | 0.9844 | 0.9958 | All | AA |
| dbCAN_4:DIAMOND | 0.9897 | 0.0198 | 0.9840 | 0.9954 | All | AA |
| dbCAN_4:dbCAN-sub | 0.9902 | 0.0189 | 0.9847 | 0.9956 | All | AA |
| CUPP | 0.9841 | 0.0215 | 0.9778 | 0.9903 | All | AA |
| dbCAN_4 | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_4:HMMER | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_4:DIAMOND | 0.9991 | 0.0029 | 0.9972 | 1.0011 | Bacteria | AA |
| dbCAN_4:dbCAN-sub | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| CUPP | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_4 | 0.9880 | 0.0207 | 0.9811 | 0.9949 | Eukaryote | AA |
| dbCAN_4:HMMER | 0.9872 | 0.0215 | 0.9800 | 0.9943 | Eukaryote | AA |
| dbCAN_4:DIAMOND | 0.9869 | 0.0217 | 0.9797 | 0.9942 | Eukaryote | AA |
| dbCAN_4:dbCAN-sub | 0.9872 | 0.0207 | 0.9803 | 0.9941 | Eukaryote | AA |
| CUPP | 0.9793 | 0.0225 | 0.9719 | 0.9868 | Eukaryote | AA |
| dbCAN_4 | 0.9763 | 0.0207 | 0.9717 | 0.9809 | All | CBM |
| dbCAN_4:HMMER | 0.9436 | 0.0300 | 0.9370 | 0.9503 | All | CBM |
| dbCAN_4:DIAMOND | 0.9830 | 0.0182 | 0.9790 | 0.9870 | All | CBM |
| dbCAN_4:dbCAN-sub | 0.9761 | 0.0244 | 0.9707 | 0.9816 | All | CBM |
| CUPP | 0.8851 | 0.0851 | 0.8662 | 0.9040 | All | CBM |
| dbCAN_4 | 0.9855 | 0.0128 | 0.9814 | 0.9896 | Bacteria | CBM |
| dbCAN_4:HMMER | 0.9494 | 0.0365 | 0.9377 | 0.9611 | Bacteria | CBM |
| dbCAN_4:DIAMOND | 0.9755 | 0.0181 | 0.9697 | 0.9812 | Bacteria | CBM |
| dbCAN_4:dbCAN-sub | 0.9892 | 0.0129 | 0.9851 | 0.9933 | Bacteria | CBM |
| CUPP | 0.8614 | 0.1127 | 0.8253 | 0.8974 | Bacteria | CBM |
| dbCAN_4 | 0.9672 | 0.0230 | 0.9598 | 0.9745 | Eukaryote | CBM |
| dbCAN_4:HMMER | 0.9379 | 0.0205 | 0.9313 | 0.9444 | Eukaryote | CBM |
| dbCAN_4:DIAMOND | 0.9905 | 0.0150 | 0.9857 | 0.9953 | Eukaryote | CBM |
| dbCAN_4:dbCAN-sub | 0.9631 | 0.0262 | 0.9547 | 0.9715 | Eukaryote | CBM |
| CUPP | 0.9088 | 0.0286 | 0.8997 | 0.9180 | Eukaryote | CBM |
8.2.5.1 Testing per CAZy class
For each CAZy class run a two-way ANOVA to determine if there statistically significant differences between the tools and taxonomic kingdoms.
## [1] "Found pairs of statistically signficant different means for GH"
## [1] "Found pairs of statistically signficant different means for GT"
## [1] "Found pairs of statistically signficant different means for PL"
## [1] "Found pairs of statistically signficant different means for CBM"9 CAZy class multilabel classification tax performance
| Prediction_tool | Lower CI | Mean | Upper CI | Standard Deviation | Tax_group |
|---|---|---|---|---|---|
| dbCAN_4 | 0.9845 | 0.9856 | 0.9866 | 0.0683 | All |
| dbCAN_4:HMMER | 0.9712 | 0.9727 | 0.9741 | 0.0920 | All |
| dbCAN_4:DIAMOND | 0.9871 | 0.9880 | 0.9890 | 0.0627 | All |
| dbCAN_4:dbCAN-sub | 0.9840 | 0.9851 | 0.9861 | 0.0694 | All |
| CUPP | 0.9580 | 0.9597 | 0.9614 | 0.1093 | All |
| dbCAN_4 | 0.9863 | 0.9877 | 0.9891 | 0.0632 | Bacteria |
| dbCAN_4:HMMER | 0.9712 | 0.9732 | 0.9752 | 0.0911 | Bacteria |
| dbCAN_4:DIAMOND | 0.9848 | 0.9863 | 0.9877 | 0.0669 | Bacteria |
| dbCAN_4:dbCAN-sub | 0.9870 | 0.9884 | 0.9897 | 0.0614 | Bacteria |
| CUPP | 0.9568 | 0.9592 | 0.9616 | 0.1101 | Bacteria |
| dbCAN_4 | 0.9819 | 0.9835 | 0.9851 | 0.0730 | Eukaryote |
| dbCAN_4:HMMER | 0.9701 | 0.9721 | 0.9741 | 0.0930 | Eukaryote |
| dbCAN_4:DIAMOND | 0.9886 | 0.9898 | 0.9911 | 0.0582 | Eukaryote |
| dbCAN_4:dbCAN-sub | 0.9801 | 0.9817 | 0.9834 | 0.0765 | Eukaryote |
| CUPP | 0.9578 | 0.9602 | 0.9625 | 0.1086 | Eukaryote |
Test for statistically significant differences between the means.
## Df Sum Sq Mean Sq F value Pr(>F)
## Tax_group 2 0.0 0.022 3.277 0.0377 *
## Prediction_tool 4 18.1 4.515 669.570 < 2e-16 ***
## Tax_group:Prediction_tool 8 0.3 0.032 4.742 7.74e-06 ***
## Residuals 159985 1078.9 0.007
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1Statistically significant difference was detected so follow up with a Tukey test to determine if there are differences between groups.
## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Rand_index_freq ~ Tax_group * Prediction_tool, data = class_tax_ri_ari_df.df)
##
## $`Tax_group:Prediction_tool`
## diff
## Bacteria:dbCAN_4-All:dbCAN_4 0.0020791667
## Eukaryote:dbCAN_4-All:dbCAN_4 -0.0020791667
## All:dbCAN_4:HMMER-All:dbCAN_4 -0.0129166667
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4 -0.0124041667
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4 -0.0134291667
## All:dbCAN_4:DIAMOND-All:dbCAN_4 0.0024416667
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4 0.0006458333
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4 0.0042375000
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4 -0.0005416667
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4 0.0027458333
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4 -0.0038291667
## All:CUPP-All:dbCAN_4 -0.0257125000
## Bacteria:CUPP-All:dbCAN_4 -0.0260791667
## Eukaryote:CUPP-All:dbCAN_4 -0.0253458333
## Eukaryote:dbCAN_4-Bacteria:dbCAN_4 -0.0041583333
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4 -0.0149958333
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4 -0.0144833333
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4 -0.0155083333
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 0.0003625000
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 -0.0014333333
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 0.0021583333
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 -0.0026208333
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 0.0006666667
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 -0.0059083333
## All:CUPP-Bacteria:dbCAN_4 -0.0277916667
## Bacteria:CUPP-Bacteria:dbCAN_4 -0.0281583333
## Eukaryote:CUPP-Bacteria:dbCAN_4 -0.0274250000
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -0.0108375000
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -0.0103250000
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -0.0113500000
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 0.0045208333
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 0.0027250000
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 0.0063166667
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 0.0015375000
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 0.0048250000
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 -0.0017500000
## All:CUPP-Eukaryote:dbCAN_4 -0.0236333333
## Bacteria:CUPP-Eukaryote:dbCAN_4 -0.0240000000
## Eukaryote:CUPP-Eukaryote:dbCAN_4 -0.0232666667
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:HMMER 0.0005125000
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:HMMER -0.0005125000
## All:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER 0.0153583333
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER 0.0135625000
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER 0.0171541667
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER 0.0123750000
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER 0.0156625000
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER 0.0090875000
## All:CUPP-All:dbCAN_4:HMMER -0.0127958333
## Bacteria:CUPP-All:dbCAN_4:HMMER -0.0131625000
## Eukaryote:CUPP-All:dbCAN_4:HMMER -0.0124291667
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:HMMER -0.0010250000
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER 0.0148458333
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER 0.0130500000
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER 0.0166416667
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER 0.0118625000
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER 0.0151500000
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER 0.0085750000
## All:CUPP-Bacteria:dbCAN_4:HMMER -0.0133083333
## Bacteria:CUPP-Bacteria:dbCAN_4:HMMER -0.0136750000
## Eukaryote:CUPP-Bacteria:dbCAN_4:HMMER -0.0129416667
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER 0.0158708333
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER 0.0140750000
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER 0.0176666667
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER 0.0128875000
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER 0.0161750000
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER 0.0096000000
## All:CUPP-Eukaryote:dbCAN_4:HMMER -0.0122833333
## Bacteria:CUPP-Eukaryote:dbCAN_4:HMMER -0.0126500000
## Eukaryote:CUPP-Eukaryote:dbCAN_4:HMMER -0.0119166667
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND -0.0017958333
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND 0.0017958333
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND -0.0029833333
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND 0.0003041667
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND -0.0062708333
## All:CUPP-All:dbCAN_4:DIAMOND -0.0281541667
## Bacteria:CUPP-All:dbCAN_4:DIAMOND -0.0285208333
## Eukaryote:CUPP-All:dbCAN_4:DIAMOND -0.0277875000
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:DIAMOND 0.0035916667
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND -0.0011875000
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND 0.0021000000
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND -0.0044750000
## All:CUPP-Bacteria:dbCAN_4:DIAMOND -0.0263583333
## Bacteria:CUPP-Bacteria:dbCAN_4:DIAMOND -0.0267250000
## Eukaryote:CUPP-Bacteria:dbCAN_4:DIAMOND -0.0259916667
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND -0.0047791667
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND -0.0014916667
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND -0.0080666667
## All:CUPP-Eukaryote:dbCAN_4:DIAMOND -0.0299500000
## Bacteria:CUPP-Eukaryote:dbCAN_4:DIAMOND -0.0303166667
## Eukaryote:CUPP-Eukaryote:dbCAN_4:DIAMOND -0.0295833333
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub 0.0032875000
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub -0.0032875000
## All:CUPP-All:dbCAN_4:dbCAN-sub -0.0251708333
## Bacteria:CUPP-All:dbCAN_4:dbCAN-sub -0.0255375000
## Eukaryote:CUPP-All:dbCAN_4:dbCAN-sub -0.0248041667
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:dbCAN-sub -0.0065750000
## All:CUPP-Bacteria:dbCAN_4:dbCAN-sub -0.0284583333
## Bacteria:CUPP-Bacteria:dbCAN_4:dbCAN-sub -0.0288250000
## Eukaryote:CUPP-Bacteria:dbCAN_4:dbCAN-sub -0.0280916667
## All:CUPP-Eukaryote:dbCAN_4:dbCAN-sub -0.0218833333
## Bacteria:CUPP-Eukaryote:dbCAN_4:dbCAN-sub -0.0222500000
## Eukaryote:CUPP-Eukaryote:dbCAN_4:dbCAN-sub -0.0215166667
## Bacteria:CUPP-All:CUPP -0.0003666667
## Eukaryote:CUPP-All:CUPP 0.0003666667
## Eukaryote:CUPP-Bacteria:CUPP 0.0007333333
## lwr
## Bacteria:dbCAN_4-All:dbCAN_4 -0.0017341844
## Eukaryote:dbCAN_4-All:dbCAN_4 -0.0058925178
## All:dbCAN_4:HMMER-All:dbCAN_4 -0.0160302548
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4 -0.0162175178
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4 -0.0172425178
## All:dbCAN_4:DIAMOND-All:dbCAN_4 -0.0006719215
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4 -0.0031675178
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4 0.0004241489
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4 -0.0036552548
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4 -0.0010675178
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4 -0.0076425178
## All:CUPP-All:dbCAN_4 -0.0288260881
## Bacteria:CUPP-All:dbCAN_4 -0.0298925178
## Eukaryote:CUPP-All:dbCAN_4 -0.0291591844
## Eukaryote:dbCAN_4-Bacteria:dbCAN_4 -0.0085616119
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4 -0.0188091844
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4 -0.0188866119
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4 -0.0199116119
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 -0.0034508511
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 -0.0058366119
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 -0.0022449452
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 -0.0064341844
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 -0.0037366119
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 -0.0103116119
## All:CUPP-Bacteria:dbCAN_4 -0.0316050178
## Bacteria:CUPP-Bacteria:dbCAN_4 -0.0325616119
## Eukaryote:CUPP-Bacteria:dbCAN_4 -0.0318282786
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -0.0146508511
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -0.0147282786
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -0.0157532786
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 0.0007074822
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 -0.0016782786
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 0.0019133881
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 -0.0022758511
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 0.0004217214
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 -0.0061532786
## All:CUPP-Eukaryote:dbCAN_4 -0.0274466844
## Bacteria:CUPP-Eukaryote:dbCAN_4 -0.0284032786
## Eukaryote:CUPP-Eukaryote:dbCAN_4 -0.0276699452
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:HMMER -0.0033008511
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:HMMER -0.0043258511
## All:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER 0.0122447452
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER 0.0097491489
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER 0.0133408156
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER 0.0092614119
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER 0.0118491489
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER 0.0052741489
## All:CUPP-All:dbCAN_4:HMMER -0.0159094215
## Bacteria:CUPP-All:dbCAN_4:HMMER -0.0169758511
## Eukaryote:CUPP-All:dbCAN_4:HMMER -0.0162425178
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:HMMER -0.0054282786
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER 0.0110324822
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER 0.0086467214
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER 0.0122383881
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER 0.0080491489
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER 0.0107467214
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER 0.0041717214
## All:CUPP-Bacteria:dbCAN_4:HMMER -0.0171216844
## Bacteria:CUPP-Bacteria:dbCAN_4:HMMER -0.0180782786
## Eukaryote:CUPP-Bacteria:dbCAN_4:HMMER -0.0173449452
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER 0.0120574822
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER 0.0096717214
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER 0.0132633881
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER 0.0090741489
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER 0.0117717214
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER 0.0051967214
## All:CUPP-Eukaryote:dbCAN_4:HMMER -0.0160966844
## Bacteria:CUPP-Eukaryote:dbCAN_4:HMMER -0.0170532786
## Eukaryote:CUPP-Eukaryote:dbCAN_4:HMMER -0.0163199452
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND -0.0056091844
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND -0.0020175178
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND -0.0060969215
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND -0.0035091844
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND -0.0100841844
## All:CUPP-All:dbCAN_4:DIAMOND -0.0312677548
## Bacteria:CUPP-All:dbCAN_4:DIAMOND -0.0323341844
## Eukaryote:CUPP-All:dbCAN_4:DIAMOND -0.0316008511
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:DIAMOND -0.0008116119
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND -0.0050008511
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND -0.0023032786
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND -0.0088782786
## All:CUPP-Bacteria:dbCAN_4:DIAMOND -0.0301716844
## Bacteria:CUPP-Bacteria:dbCAN_4:DIAMOND -0.0311282786
## Eukaryote:CUPP-Bacteria:dbCAN_4:DIAMOND -0.0303949452
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND -0.0085925178
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND -0.0058949452
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND -0.0124699452
## All:CUPP-Eukaryote:dbCAN_4:DIAMOND -0.0337633511
## Bacteria:CUPP-Eukaryote:dbCAN_4:DIAMOND -0.0347199452
## Eukaryote:CUPP-Eukaryote:dbCAN_4:DIAMOND -0.0339866119
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub -0.0005258511
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub -0.0071008511
## All:CUPP-All:dbCAN_4:dbCAN-sub -0.0282844215
## Bacteria:CUPP-All:dbCAN_4:dbCAN-sub -0.0293508511
## Eukaryote:CUPP-All:dbCAN_4:dbCAN-sub -0.0286175178
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:dbCAN-sub -0.0109782786
## All:CUPP-Bacteria:dbCAN_4:dbCAN-sub -0.0322716844
## Bacteria:CUPP-Bacteria:dbCAN_4:dbCAN-sub -0.0332282786
## Eukaryote:CUPP-Bacteria:dbCAN_4:dbCAN-sub -0.0324949452
## All:CUPP-Eukaryote:dbCAN_4:dbCAN-sub -0.0256966844
## Bacteria:CUPP-Eukaryote:dbCAN_4:dbCAN-sub -0.0266532786
## Eukaryote:CUPP-Eukaryote:dbCAN_4:dbCAN-sub -0.0259199452
## Bacteria:CUPP-All:CUPP -0.0041800178
## Eukaryote:CUPP-All:CUPP -0.0034466844
## Eukaryote:CUPP-Bacteria:CUPP -0.0036699452
## upr p adj
## Bacteria:dbCAN_4-All:dbCAN_4 5.892518e-03 0.8779199
## Eukaryote:dbCAN_4-All:dbCAN_4 1.734184e-03 0.8779199
## All:dbCAN_4:HMMER-All:dbCAN_4 -9.803079e-03 0.0000000
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4 -8.590816e-03 0.0000000
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4 -9.615816e-03 0.0000000
## All:dbCAN_4:DIAMOND-All:dbCAN_4 5.555255e-03 0.3301877
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4 4.459184e-03 0.9999996
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4 8.050851e-03 0.0137079
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4 2.571921e-03 0.9999995
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4 6.559184e-03 0.4831887
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4 -1.581558e-05 0.0478177
## All:CUPP-All:dbCAN_4 -2.259891e-02 0.0000000
## Bacteria:CUPP-All:dbCAN_4 -2.226582e-02 0.0000000
## Eukaryote:CUPP-All:dbCAN_4 -2.153248e-02 0.0000000
## Eukaryote:dbCAN_4-Bacteria:dbCAN_4 2.449452e-04 0.0884004
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4 -1.118248e-02 0.0000000
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4 -1.008005e-02 0.0000000
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4 -1.110505e-02 0.0000000
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 4.175851e-03 1.0000000
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 2.969945e-03 0.9989136
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 6.561612e-03 0.9442833
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 1.192518e-03 0.5672374
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 5.069945e-03 0.9999999
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 -1.505055e-03 0.0005233
## All:CUPP-Bacteria:dbCAN_4 -2.397832e-02 0.0000000
## Bacteria:CUPP-Bacteria:dbCAN_4 -2.375505e-02 0.0000000
## Eukaryote:CUPP-Bacteria:dbCAN_4 -2.302172e-02 0.0000000
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -7.024149e-03 0.0000000
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -5.921721e-03 0.0000000
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -6.946721e-03 0.0000000
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 8.334184e-03 0.0051928
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 7.128279e-03 0.7361635
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 1.071995e-02 0.0001152
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 5.350851e-03 0.9900225
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 9.228279e-03 0.0166013
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 2.653279e-03 0.9913192
## All:CUPP-Eukaryote:dbCAN_4 -1.981998e-02 0.0000000
## Bacteria:CUPP-Eukaryote:dbCAN_4 -1.959672e-02 0.0000000
## Eukaryote:CUPP-Eukaryote:dbCAN_4 -1.886339e-02 0.0000000
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:HMMER 4.325851e-03 1.0000000
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:HMMER 3.300851e-03 1.0000000
## All:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER 1.847192e-02 0.0000000
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER 1.737585e-02 0.0000000
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER 2.096752e-02 0.0000000
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER 1.548859e-02 0.0000000
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER 1.947585e-02 0.0000000
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER 1.290085e-02 0.0000000
## All:CUPP-All:dbCAN_4:HMMER -9.682245e-03 0.0000000
## Bacteria:CUPP-All:dbCAN_4:HMMER -9.349149e-03 0.0000000
## Eukaryote:CUPP-All:dbCAN_4:HMMER -8.615816e-03 0.0000000
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:HMMER 3.378279e-03 0.9999791
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER 1.865918e-02 0.0000000
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER 1.745328e-02 0.0000000
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER 2.104495e-02 0.0000000
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER 1.567585e-02 0.0000000
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER 1.955328e-02 0.0000000
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER 1.297828e-02 0.0000000
## All:CUPP-Bacteria:dbCAN_4:HMMER -9.494982e-03 0.0000000
## Bacteria:CUPP-Bacteria:dbCAN_4:HMMER -9.271721e-03 0.0000000
## Eukaryote:CUPP-Bacteria:dbCAN_4:HMMER -8.538388e-03 0.0000000
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER 1.968418e-02 0.0000000
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER 1.847828e-02 0.0000000
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER 2.206995e-02 0.0000000
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER 1.670085e-02 0.0000000
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER 2.057828e-02 0.0000000
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER 1.400328e-02 0.0000000
## All:CUPP-Eukaryote:dbCAN_4:HMMER -8.469982e-03 0.0000000
## Bacteria:CUPP-Eukaryote:dbCAN_4:HMMER -8.246721e-03 0.0000000
## Eukaryote:CUPP-Eukaryote:dbCAN_4:HMMER -7.513388e-03 0.0000000
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND 2.017518e-03 0.9597235
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND 5.609184e-03 0.9597235
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND 1.302548e-04 0.0771415
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND 4.117518e-03 1.0000000
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND -2.457482e-03 0.0000025
## All:CUPP-All:dbCAN_4:DIAMOND -2.504058e-02 0.0000000
## Bacteria:CUPP-All:dbCAN_4:DIAMOND -2.470748e-02 0.0000000
## Eukaryote:CUPP-All:dbCAN_4:DIAMOND -2.397415e-02 0.0000000
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:DIAMOND 7.994945e-03 0.2653212
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND 2.625851e-03 0.9993369
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND 6.503279e-03 0.9553075
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND -7.172145e-05 0.0418918
## All:CUPP-Bacteria:dbCAN_4:DIAMOND -2.254498e-02 0.0000000
## Bacteria:CUPP-Bacteria:dbCAN_4:DIAMOND -2.232172e-02 0.0000000
## Eukaryote:CUPP-Bacteria:dbCAN_4:DIAMOND -2.158839e-02 0.0000000
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND -9.658156e-04 0.0020001
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND 2.911612e-03 0.9983212
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND -3.663388e-03 0.0000001
## All:CUPP-Eukaryote:dbCAN_4:DIAMOND -2.613665e-02 0.0000000
## Bacteria:CUPP-Eukaryote:dbCAN_4:DIAMOND -2.591339e-02 0.0000000
## Eukaryote:CUPP-Eukaryote:dbCAN_4:DIAMOND -2.518005e-02 0.0000000
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub 7.100851e-03 0.1852148
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub 5.258511e-04 0.1852148
## All:CUPP-All:dbCAN_4:dbCAN-sub -2.205725e-02 0.0000000
## Bacteria:CUPP-All:dbCAN_4:dbCAN-sub -2.172415e-02 0.0000000
## Eukaryote:CUPP-All:dbCAN_4:dbCAN-sub -2.099082e-02 0.0000000
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:dbCAN-sub -2.171721e-03 0.0000419
## All:CUPP-Bacteria:dbCAN_4:dbCAN-sub -2.464498e-02 0.0000000
## Bacteria:CUPP-Bacteria:dbCAN_4:dbCAN-sub -2.442172e-02 0.0000000
## Eukaryote:CUPP-Bacteria:dbCAN_4:dbCAN-sub -2.368839e-02 0.0000000
## All:CUPP-Eukaryote:dbCAN_4:dbCAN-sub -1.806998e-02 0.0000000
## Bacteria:CUPP-Eukaryote:dbCAN_4:dbCAN-sub -1.784672e-02 0.0000000
## Eukaryote:CUPP-Eukaryote:dbCAN_4:dbCAN-sub -1.711339e-02 0.0000000
## Bacteria:CUPP-All:CUPP 3.446684e-03 1.0000000
## Eukaryote:CUPP-All:CUPP 4.180018e-03 1.0000000
## Eukaryote:CUPP-Bacteria:CUPP 5.136612e-03 0.9999997## Df Sum Sq Mean Sq F value Pr(>F)
## Tax_group 2 0 0.180 3.463 0.031348 *
## Prediction_tool 4 122 30.493 585.609 < 2e-16 ***
## Tax_group:Prediction_tool 8 2 0.193 3.701 0.000248 ***
## Residuals 159985 8331 0.052
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1Statistically significant difference was detected so follow up with a Tukey test to determine if there are differences between groups.
## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Adjusted_Rand_index_freq ~ Tax_group * Prediction_tool, data = class_tax_ri_ari_df.df)
##
## $`Tax_group:Prediction_tool`
## diff
## Bacteria:dbCAN_4-All:dbCAN_4 0.0048822709
## Eukaryote:dbCAN_4-All:dbCAN_4 -0.0048822709
## All:dbCAN_4:HMMER-All:dbCAN_4 -0.0354371108
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4 -0.0352604289
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4 -0.0356137926
## All:dbCAN_4:DIAMOND-All:dbCAN_4 0.0061464454
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4 0.0014381610
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4 0.0108547297
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4 -0.0013459900
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4 0.0069620300
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4 -0.0096540100
## All:CUPP-All:dbCAN_4 -0.0662991870
## Bacteria:CUPP-All:dbCAN_4 -0.0643422782
## Eukaryote:CUPP-All:dbCAN_4 -0.0682560958
## Eukaryote:dbCAN_4-Bacteria:dbCAN_4 -0.0097645417
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4 -0.0403193816
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4 -0.0401426998
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4 -0.0404960635
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 0.0012641745
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 -0.0034441099
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 0.0059724589
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 -0.0062282609
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 0.0020797591
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 -0.0145362808
## All:CUPP-Bacteria:dbCAN_4 -0.0711814579
## Bacteria:CUPP-Bacteria:dbCAN_4 -0.0692245491
## Eukaryote:CUPP-Bacteria:dbCAN_4 -0.0731383666
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -0.0305548399
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -0.0303781580
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -0.0307315217
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 0.0110287162
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 0.0063204318
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 0.0157370006
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 0.0035362808
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 0.0118443008
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 -0.0047717391
## All:CUPP-Eukaryote:dbCAN_4 -0.0614169161
## Bacteria:CUPP-Eukaryote:dbCAN_4 -0.0594600074
## Eukaryote:CUPP-Eukaryote:dbCAN_4 -0.0633738249
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:HMMER 0.0001766818
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:HMMER -0.0001766818
## All:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER 0.0415835561
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER 0.0368752717
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER 0.0462918405
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER 0.0340911207
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER 0.0423991407
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER 0.0257831008
## All:CUPP-All:dbCAN_4:HMMER -0.0308620763
## Bacteria:CUPP-All:dbCAN_4:HMMER -0.0289051675
## Eukaryote:CUPP-All:dbCAN_4:HMMER -0.0328189850
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:HMMER -0.0003533637
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER 0.0414068743
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER 0.0366985899
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER 0.0461151586
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER 0.0339144389
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER 0.0422224589
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER 0.0256064189
## All:CUPP-Bacteria:dbCAN_4:HMMER -0.0310387581
## Bacteria:CUPP-Bacteria:dbCAN_4:HMMER -0.0290818493
## Eukaryote:CUPP-Bacteria:dbCAN_4:HMMER -0.0329956669
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER 0.0417602380
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER 0.0370519536
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER 0.0464685223
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER 0.0342678026
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER 0.0425758226
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER 0.0259597826
## All:CUPP-Eukaryote:dbCAN_4:HMMER -0.0306853944
## Bacteria:CUPP-Eukaryote:dbCAN_4:HMMER -0.0287284856
## Eukaryote:CUPP-Eukaryote:dbCAN_4:HMMER -0.0326423032
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND -0.0047082844
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND 0.0047082844
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND -0.0074924354
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND 0.0008155846
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND -0.0158004553
## All:CUPP-All:dbCAN_4:DIAMOND -0.0724456324
## Bacteria:CUPP-All:dbCAN_4:DIAMOND -0.0704887236
## Eukaryote:CUPP-All:dbCAN_4:DIAMOND -0.0744025411
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:DIAMOND 0.0094165687
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND -0.0027841510
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND 0.0055238690
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND -0.0110921710
## All:CUPP-Bacteria:dbCAN_4:DIAMOND -0.0677373480
## Bacteria:CUPP-Bacteria:dbCAN_4:DIAMOND -0.0657804392
## Eukaryote:CUPP-Bacteria:dbCAN_4:DIAMOND -0.0696942568
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND -0.0122007197
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND -0.0038926998
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND -0.0205087397
## All:CUPP-Eukaryote:dbCAN_4:DIAMOND -0.0771539167
## Bacteria:CUPP-Eukaryote:dbCAN_4:DIAMOND -0.0751970080
## Eukaryote:CUPP-Eukaryote:dbCAN_4:DIAMOND -0.0791108255
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub 0.0083080200
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub -0.0083080200
## All:CUPP-All:dbCAN_4:dbCAN-sub -0.0649531970
## Bacteria:CUPP-All:dbCAN_4:dbCAN-sub -0.0629962882
## Eukaryote:CUPP-All:dbCAN_4:dbCAN-sub -0.0669101058
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:dbCAN-sub -0.0166160400
## All:CUPP-Bacteria:dbCAN_4:dbCAN-sub -0.0732612170
## Bacteria:CUPP-Bacteria:dbCAN_4:dbCAN-sub -0.0713043082
## Eukaryote:CUPP-Bacteria:dbCAN_4:dbCAN-sub -0.0752181257
## All:CUPP-Eukaryote:dbCAN_4:dbCAN-sub -0.0566451770
## Bacteria:CUPP-Eukaryote:dbCAN_4:dbCAN-sub -0.0546882683
## Eukaryote:CUPP-Eukaryote:dbCAN_4:dbCAN-sub -0.0586020858
## Bacteria:CUPP-All:CUPP 0.0019569088
## Eukaryote:CUPP-All:CUPP -0.0019569088
## Eukaryote:CUPP-Bacteria:CUPP -0.0039138175
## lwr
## Bacteria:dbCAN_4-All:dbCAN_4 -0.0057140640
## Eukaryote:dbCAN_4-All:dbCAN_4 -0.0154786057
## All:dbCAN_4:HMMER-All:dbCAN_4 -0.0440889819
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4 -0.0458567637
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4 -0.0462101274
## All:dbCAN_4:DIAMOND-All:dbCAN_4 -0.0025054258
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4 -0.0091581738
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4 0.0002583949
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4 -0.0099978612
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4 -0.0036343049
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4 -0.0202503448
## All:CUPP-All:dbCAN_4 -0.0749510582
## Bacteria:CUPP-All:dbCAN_4 -0.0749386131
## Eukaryote:CUPP-All:dbCAN_4 -0.0788524306
## Eukaryote:dbCAN_4-Bacteria:dbCAN_4 -0.0220001353
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4 -0.0509157164
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4 -0.0523782933
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4 -0.0527316570
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 -0.0093321603
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 -0.0156797034
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 -0.0062631347
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 -0.0168245957
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 -0.0101558344
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 -0.0267718744
## All:CUPP-Bacteria:dbCAN_4 -0.0817777927
## Bacteria:CUPP-Bacteria:dbCAN_4 -0.0814601426
## Eukaryote:CUPP-Bacteria:dbCAN_4 -0.0853739602
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -0.0411511747
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -0.0426137516
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -0.0429671153
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 0.0004323814
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 -0.0059151617
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 0.0035014070
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 -0.0070600540
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 -0.0003912927
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 -0.0170073327
## All:CUPP-Eukaryote:dbCAN_4 -0.0720132510
## Bacteria:CUPP-Eukaryote:dbCAN_4 -0.0716956009
## Eukaryote:CUPP-Eukaryote:dbCAN_4 -0.0756094184
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:HMMER -0.0104196530
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:HMMER -0.0107730167
## All:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER 0.0329316849
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER 0.0262789369
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER 0.0356955056
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER 0.0254392496
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER 0.0318028059
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER 0.0151867659
## All:CUPP-All:dbCAN_4:HMMER -0.0395139474
## Bacteria:CUPP-All:dbCAN_4:HMMER -0.0395015023
## Eukaryote:CUPP-All:dbCAN_4:HMMER -0.0434153199
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:HMMER -0.0125889572
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER 0.0308105394
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER 0.0244629964
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER 0.0338795651
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER 0.0233181041
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER 0.0299868653
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER 0.0133708254
## All:CUPP-Bacteria:dbCAN_4:HMMER -0.0416350929
## Bacteria:CUPP-Bacteria:dbCAN_4:HMMER -0.0413174429
## Eukaryote:CUPP-Bacteria:dbCAN_4:HMMER -0.0452312604
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER 0.0311639031
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER 0.0248163600
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER 0.0342329288
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER 0.0236714678
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER 0.0303402290
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER 0.0137241891
## All:CUPP-Eukaryote:dbCAN_4:HMMER -0.0412817292
## Bacteria:CUPP-Eukaryote:dbCAN_4:HMMER -0.0409640792
## Eukaryote:CUPP-Eukaryote:dbCAN_4:HMMER -0.0448778967
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND -0.0153046192
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND -0.0058880505
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND -0.0161443065
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND -0.0097807502
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND -0.0263967902
## All:CUPP-All:dbCAN_4:DIAMOND -0.0810975035
## Bacteria:CUPP-All:dbCAN_4:DIAMOND -0.0810850584
## Eukaryote:CUPP-All:dbCAN_4:DIAMOND -0.0849988760
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:DIAMOND -0.0028190248
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND -0.0133804858
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND -0.0067117246
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND -0.0233277645
## All:CUPP-Bacteria:dbCAN_4:DIAMOND -0.0783336828
## Bacteria:CUPP-Bacteria:dbCAN_4:DIAMOND -0.0780160328
## Eukaryote:CUPP-Bacteria:dbCAN_4:DIAMOND -0.0819298503
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND -0.0227970546
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND -0.0161282933
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND -0.0327443333
## All:CUPP-Eukaryote:dbCAN_4:DIAMOND -0.0877502516
## Bacteria:CUPP-Eukaryote:dbCAN_4:DIAMOND -0.0874326015
## Eukaryote:CUPP-Eukaryote:dbCAN_4:DIAMOND -0.0913464190
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub -0.0022883149
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub -0.0189043548
## All:CUPP-All:dbCAN_4:dbCAN-sub -0.0736050682
## Bacteria:CUPP-All:dbCAN_4:dbCAN-sub -0.0735926231
## Eukaryote:CUPP-All:dbCAN_4:dbCAN-sub -0.0775064406
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:dbCAN-sub -0.0288516335
## All:CUPP-Bacteria:dbCAN_4:dbCAN-sub -0.0838575518
## Bacteria:CUPP-Bacteria:dbCAN_4:dbCAN-sub -0.0835399017
## Eukaryote:CUPP-Bacteria:dbCAN_4:dbCAN-sub -0.0874537193
## All:CUPP-Eukaryote:dbCAN_4:dbCAN-sub -0.0672415119
## Bacteria:CUPP-Eukaryote:dbCAN_4:dbCAN-sub -0.0669238618
## Eukaryote:CUPP-Eukaryote:dbCAN_4:dbCAN-sub -0.0708376793
## Bacteria:CUPP-All:CUPP -0.0086394261
## Eukaryote:CUPP-All:CUPP -0.0125532436
## Eukaryote:CUPP-Bacteria:CUPP -0.0161494111
## upr p adj
## Bacteria:dbCAN_4-All:dbCAN_4 0.0154786057 0.9664804
## Eukaryote:dbCAN_4-All:dbCAN_4 0.0057140640 0.9664804
## All:dbCAN_4:HMMER-All:dbCAN_4 -0.0267852396 0.0000000
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4 -0.0246640941 0.0000000
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4 -0.0250174578 0.0000000
## All:dbCAN_4:DIAMOND-All:dbCAN_4 0.0147983165 0.5077465
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4 0.0120344958 1.0000000
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4 0.0214510646 0.0383013
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4 0.0073058812 0.9999999
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4 0.0175583648 0.6443527
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4 0.0009423248 0.1210943
## All:CUPP-All:dbCAN_4 -0.0576473158 0.0000000
## Bacteria:CUPP-All:dbCAN_4 -0.0537459434 0.0000000
## Eukaryote:CUPP-All:dbCAN_4 -0.0576597609 0.0000000
## Eukaryote:dbCAN_4-Bacteria:dbCAN_4 0.0024710518 0.3006665
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4 -0.0297230468 0.0000000
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4 -0.0279071062 0.0000000
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4 -0.0282604699 0.0000000
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 0.0118605093 1.0000000
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 0.0087914837 0.9997925
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 0.0182080524 0.9460995
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 0.0043680740 0.8028230
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 0.0143153526 0.9999996
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 -0.0023006873 0.0050186
## All:CUPP-Bacteria:dbCAN_4 -0.0605851230 0.0000000
## Bacteria:CUPP-Bacteria:dbCAN_4 -0.0569889556 0.0000000
## Eukaryote:CUPP-Bacteria:dbCAN_4 -0.0609027731 0.0000000
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -0.0199585051 0.0000000
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -0.0181425645 0.0000000
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -0.0184959282 0.0000000
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 0.0216250511 0.0318314
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 0.0185560254 0.9167800
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 0.0279725941 0.0012302
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 0.0141326157 0.9985728
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 0.0240798944 0.0698425
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 0.0074638544 0.9927878
## All:CUPP-Eukaryote:dbCAN_4 -0.0508205813 0.0000000
## Bacteria:CUPP-Eukaryote:dbCAN_4 -0.0472244138 0.0000000
## Eukaryote:CUPP-Eukaryote:dbCAN_4 -0.0511382314 0.0000000
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:HMMER 0.0107730167 1.0000000
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:HMMER 0.0104196530 1.0000000
## All:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER 0.0502354273 0.0000000
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER 0.0474716066 0.0000000
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER 0.0568881753 0.0000000
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER 0.0427429919 0.0000000
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER 0.0529954756 0.0000000
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER 0.0363794356 0.0000000
## All:CUPP-All:dbCAN_4:HMMER -0.0222102051 0.0000000
## Bacteria:CUPP-All:dbCAN_4:HMMER -0.0183088327 0.0000000
## Eukaryote:CUPP-All:dbCAN_4:HMMER -0.0222226502 0.0000000
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:HMMER 0.0118822298 1.0000000
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER 0.0520032091 0.0000000
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER 0.0489341834 0.0000000
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER 0.0583507522 0.0000000
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER 0.0445107737 0.0000000
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER 0.0544580524 0.0000000
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER 0.0378420125 0.0000000
## All:CUPP-Bacteria:dbCAN_4:HMMER -0.0204424233 0.0000000
## Bacteria:CUPP-Bacteria:dbCAN_4:HMMER -0.0168462558 0.0000000
## Eukaryote:CUPP-Bacteria:dbCAN_4:HMMER -0.0207600733 0.0000000
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER 0.0523565728 0.0000000
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER 0.0492875471 0.0000000
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER 0.0587041159 0.0000000
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER 0.0448641374 0.0000000
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER 0.0548114161 0.0000000
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER 0.0381953761 0.0000000
## All:CUPP-Eukaryote:dbCAN_4:HMMER -0.0200890596 0.0000000
## Bacteria:CUPP-Eukaryote:dbCAN_4:HMMER -0.0164928921 0.0000000
## Eukaryote:CUPP-Eukaryote:dbCAN_4:HMMER -0.0204067096 0.0000000
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND 0.0058880505 0.9755248
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND 0.0153046192 0.9755248
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND 0.0011594358 0.1793734
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND 0.0114119194 1.0000000
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND -0.0052041205 0.0000434
## All:CUPP-All:dbCAN_4:DIAMOND -0.0637937612 0.0000000
## Bacteria:CUPP-All:dbCAN_4:DIAMOND -0.0598923888 0.0000000
## Eukaryote:CUPP-All:dbCAN_4:DIAMOND -0.0638062063 0.0000000
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:DIAMOND 0.0216521623 0.3628543
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND 0.0078121838 0.9999084
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND 0.0177594625 0.9718647
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND 0.0011434226 0.1261807
## All:CUPP-Bacteria:dbCAN_4:DIAMOND -0.0571410132 0.0000000
## Bacteria:CUPP-Bacteria:dbCAN_4:DIAMOND -0.0535448457 0.0000000
## Eukaryote:CUPP-Bacteria:dbCAN_4:DIAMOND -0.0574586632 0.0000000
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND -0.0016043849 0.0081916
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND 0.0083428938 0.9991571
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND -0.0082731462 0.0000014
## All:CUPP-Eukaryote:dbCAN_4:DIAMOND -0.0665575819 0.0000000
## Bacteria:CUPP-Eukaryote:dbCAN_4:DIAMOND -0.0629614144 0.0000000
## Eukaryote:CUPP-Eukaryote:dbCAN_4:DIAMOND -0.0668752320 0.0000000
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub 0.0189043548 0.3305167
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub 0.0022883149 0.3305167
## All:CUPP-All:dbCAN_4:dbCAN-sub -0.0563013258 0.0000000
## Bacteria:CUPP-All:dbCAN_4:dbCAN-sub -0.0523999534 0.0000000
## Eukaryote:CUPP-All:dbCAN_4:dbCAN-sub -0.0563137709 0.0000000
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:dbCAN-sub -0.0043804464 0.0004049
## All:CUPP-Bacteria:dbCAN_4:dbCAN-sub -0.0626648821 0.0000000
## Bacteria:CUPP-Bacteria:dbCAN_4:dbCAN-sub -0.0590687147 0.0000000
## Eukaryote:CUPP-Bacteria:dbCAN_4:dbCAN-sub -0.0629825322 0.0000000
## All:CUPP-Eukaryote:dbCAN_4:dbCAN-sub -0.0460488422 0.0000000
## Bacteria:CUPP-Eukaryote:dbCAN_4:dbCAN-sub -0.0424526747 0.0000000
## Eukaryote:CUPP-Eukaryote:dbCAN_4:dbCAN-sub -0.0463664922 0.0000000
## Bacteria:CUPP-All:CUPP 0.0125532436 0.9999989
## Eukaryote:CUPP-All:CUPP 0.0086394261 0.9999989
## Eukaryote:CUPP-Bacteria:CUPP 0.0083217760 0.999104810 CAZy family classification
The following section evaluates the performance of the CAZyme classifiers to predict CAZy family classifications.
10.1 General trends in performance across all CAZy families
Below is a table summarising the overall CAZy family classifications for across all CAZy families, when pooling all test sets.
| Classifier | Spec Mean | Spec Standard Deviation | Spec Lower CI | Spec Upper CI | Sens Mean | Sens Standard Deviation | Sens Lower CI | Sens Upper CI | Prec Mean | Prec Standard Deviation | Prec Lower CI | Prec Upper CI | F1-score Mean | F1-score Standard Deviation | F1-score Lower CI | F1-score Upper CI | Acc Mean | Acc Standard Deviation | Acc Lower CI | Acc Upper CI |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CUPP | 0.9999 | 3e-04 | 0.9999 | 1.0000 | 0.6422 | 0.4389 | 0.5940 | 0.6904 | 0.6793 | 0.4519 | 0.6297 | 0.7290 | 0.6511 | 0.4385 | 0.6029 | 0.6992 | 0.9992 | 0.0021 | 0.9990 | 0.9994 |
| dbCAN_4 | 0.9999 | 3e-04 | 0.9999 | 0.9999 | 0.9001 | 0.2615 | 0.8716 | 0.9286 | 0.8906 | 0.2705 | 0.8612 | 0.9201 | 0.8856 | 0.2636 | 0.8569 | 0.9143 | 0.9996 | 0.0012 | 0.9995 | 0.9998 |
| dbCAN_4:dbCAN-sub | 0.9999 | 4e-04 | 0.9998 | 0.9999 | 0.8905 | 0.2722 | 0.8609 | 0.9201 | 0.8811 | 0.2802 | 0.8506 | 0.9116 | 0.8750 | 0.2736 | 0.8452 | 0.9047 | 0.9996 | 0.0012 | 0.9995 | 0.9998 |
| dbCAN_4:DIAMOND | 0.9999 | 3e-04 | 0.9998 | 0.9999 | 0.9379 | 0.1941 | 0.9166 | 0.9591 | 0.9231 | 0.2059 | 0.9005 | 0.9457 | 0.9229 | 0.1985 | 0.9012 | 0.9447 | 0.9997 | 0.0007 | 0.9997 | 0.9998 |
| dbCAN_4:HMMER | 0.9999 | 4e-04 | 0.9998 | 0.9999 | 0.8576 | 0.2976 | 0.8253 | 0.8898 | 0.8695 | 0.2934 | 0.8377 | 0.9013 | 0.8501 | 0.2933 | 0.8183 | 0.8819 | 0.9994 | 0.0019 | 0.9992 | 0.9996 |
Here we plot the 95% confidence intervals for CAZy class classification, when pooling all CAZy classes and test sets.
Figure 10.1: Summary statistics of CAZyme classifiers performances of CAZy family classification, plotting the mean plus and minus the 95% confidence interval.
To evaluate the overall performance of each classifier, for each CAZy family, the F1-score was calculated for every family. Families were grouped by their parent CAZy class and the distribution of the F1-scores is shown in figure 10.2.
Figure 10.2: Proportaional area plot of F1-score per CAZy distribution per CAZy class.
10.2 Below is a table displaying the number of test sets in which each CAZy class was present, and were used to draw the proporitonal areas for each class in figure10.2.
| Prediction_tool | GH | GT | PL | CE | AA | CBM |
|---|---|---|---|---|---|---|
| dbCAN_2 | 0 | 0 | 0 | 0 | 0 | 0 |
| dbCAN_2:HMMER | 0 | 0 | 0 | 0 | 0 | 0 |
| dbCAN_2:DIAMOND | 0 | 0 | 0 | 0 | 0 | 0 |
| dbCAN_2:Hotpep | 0 | 0 | 0 | 0 | 0 | 0 |
| dbCAN_3 | 0 | 0 | 0 | 0 | 0 | 0 |
| dbCAN_3:HMMER | 0 | 0 | 0 | 0 | 0 | 0 |
| dbCAN_3:DIAMOND | 0 | 0 | 0 | 0 | 0 | 0 |
| dbCAN_3:eCAMI | 0 | 0 | 0 | 0 | 0 | 0 |
| dbCAN_4 | 137 | 76 | 23 | 18 | 16 | 56 |
| dbCAN_4:HMMER | 139 | 77 | 23 | 18 | 16 | 56 |
| dbCAN_4:DIAMOND | 135 | 76 | 23 | 17 | 16 | 55 |
| dbCAN_4:dbCAN-sub | 138 | 76 | 23 | 18 | 16 | 56 |
| CUPP | 135 | 75 | 23 | 17 | 16 | 55 |
Now the distribution of F1-scores of CAZyme family classification is calculated for each tool, per CAZyme class.
## Prediction_tool GH_1 GH_0.9 GH_0.75 GT_1 GT_0.9 GT_0.75
## 1 dbCAN_4 56.93431 87.59124 6.569343 47.36842 80.26316 11.842105
## 2 dbCAN_4:HMMER 49.64029 81.29496 9.352518 41.55844 67.53247 16.883117
## 3 dbCAN_4:DIAMOND 60.74074 90.37037 3.703704 52.63158 85.52632 9.210526
## 4 dbCAN_4:dbCAN-sub 52.89855 85.50725 8.695652 46.05263 80.26316 11.842105
## 5 CUPP 41.48148 70.37037 20.000000 33.33333 69.33333 22.666667
## PL_1 PL_0.9 PL_0.75 CE_1 CE_0.9 CE_0.75 AA_1 AA_0.9 AA_0.75
## 1 69.56522 78.26087 13.04348 33.33333 61.11111 22.22222 37.5 62.50 18.75
## 2 69.56522 78.26087 13.04348 27.77778 55.55556 22.22222 37.5 62.50 18.75
## 3 78.26087 86.95652 13.04348 47.05882 70.58824 17.64706 37.5 56.25 12.50
## 4 69.56522 78.26087 13.04348 33.33333 61.11111 22.22222 37.5 62.50 18.75
## 5 52.17391 60.86957 34.78261 35.29412 58.82353 35.29412 25.0 56.25 31.25
## CBM_1 CBM_0.9 CBM_0.75
## 1 55.35714 73.21429 19.64286
## 2 46.42857 55.35714 26.78571
## 3 52.72727 80.00000 14.54545
## 4 46.42857 69.64286 25.00000
## 5 0.00000 0.00000 100.00000To evaluate the performance of predicting each CAZy family independent of all other CAZy families, the sensitivity and precision for each CAZy family, for each CAZyme classifier was calculated and plotted against each other. Whereas sensitivity was plotted against sensitivity for CAZy classes, owing to the extremely small variation in specificity scores, sensitivity was plotted as a percentage against log10 of the specificity percentage.
The following plots present the specificity (Fig.10.4), sensitivity (Fig.10.6), precision (Fig.10.8), F1-score (Fig.10.10) and accuracy (Fig.10.12) for each CAZy family per classifier. In accompaniment to each plot is a table summarising the mean statistic value for each classifier across all CAZy families for each CAZy class.
10.2 Statsitically testing across all CAZyme classes
Pooling all CAZymes across all test sets, and pooling all CAzyme families from all CAZyme classes, the mean of each statistical metric is tested for statistically significant differences across the CAZyme prediction tools.
10.2.1 Comparing means between CAZyme class and CAZyme family classification performances
Test for a statistically significant difference in the mean between the CAZyme class and CAZyme family classification performances.
## Df Sum Sq Mean Sq F value Pr(>F)
## Prediction_tool 4 13.39 3.347 79.05 <2e-16 ***
## Residuals 2050 86.80 0.042
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 110.2.2 Specificity
| CAZy_class | Prediction_tool | Mean | Standard Deviation | Lower CI | Upper CI |
|---|---|---|---|---|---|
| GH | dbCAN_4 | 1.0000 | 1e-04 | 0.9999 | 1.0000 |
| GH | dbCAN_4:HMMER | 0.9999 | 1e-04 | 0.9999 | 1.0000 |
| GH | dbCAN_4:DIAMOND | 0.9999 | 2e-04 | 0.9999 | 1.0000 |
| GH | dbCAN_4:dbCAN-sub | 0.9999 | 2e-04 | 0.9999 | 1.0000 |
| GH | CUPP | 0.9999 | 2e-04 | 0.9999 | 1.0000 |
| GT | dbCAN_4 | 0.9999 | 3e-04 | 0.9998 | 0.9999 |
| GT | dbCAN_4:HMMER | 0.9999 | 3e-04 | 0.9998 | 0.9999 |
| GT | dbCAN_4:DIAMOND | 0.9999 | 3e-04 | 0.9998 | 0.9999 |
| GT | dbCAN_4:dbCAN-sub | 0.9998 | 3e-04 | 0.9998 | 0.9999 |
| GT | CUPP | 0.9999 | 2e-04 | 0.9999 | 1.0000 |
| PL | dbCAN_4 | 1.0000 | 0e+00 | 1.0000 | 1.0000 |
| PL | dbCAN_4:HMMER | 1.0000 | 0e+00 | 1.0000 | 1.0000 |
| PL | dbCAN_4:DIAMOND | 1.0000 | 1e-04 | 0.9999 | 1.0000 |
| PL | dbCAN_4:dbCAN-sub | 1.0000 | 0e+00 | 1.0000 | 1.0000 |
| PL | CUPP | 1.0000 | 0e+00 | 1.0000 | 1.0000 |
| CE | dbCAN_4 | 0.9996 | 9e-04 | 0.9991 | 1.0000 |
| CE | dbCAN_4:HMMER | 0.9996 | 9e-04 | 0.9991 | 1.0000 |
| CE | dbCAN_4:DIAMOND | 0.9996 | 9e-04 | 0.9991 | 1.0000 |
| CE | dbCAN_4:dbCAN-sub | 0.9996 | 9e-04 | 0.9991 | 1.0000 |
| CE | CUPP | 0.9996 | 9e-04 | 0.9991 | 1.0001 |
| AA | dbCAN_4 | 0.9996 | 7e-04 | 0.9993 | 1.0000 |
| AA | dbCAN_4:HMMER | 0.9996 | 7e-04 | 0.9993 | 1.0000 |
| AA | dbCAN_4:DIAMOND | 0.9996 | 6e-04 | 0.9993 | 0.9999 |
| AA | dbCAN_4:dbCAN-sub | 0.9996 | 7e-04 | 0.9993 | 1.0000 |
| AA | CUPP | 0.9997 | 7e-04 | 0.9993 | 1.0000 |
| CBM | dbCAN_4 | 0.9999 | 4e-04 | 0.9998 | 1.0000 |
| CBM | dbCAN_4:HMMER | 0.9999 | 4e-04 | 0.9998 | 1.0000 |
| CBM | dbCAN_4:DIAMOND | 0.9999 | 2e-04 | 0.9998 | 0.9999 |
| CBM | dbCAN_4:dbCAN-sub | 0.9998 | 5e-04 | 0.9997 | 1.0000 |
| CBM | CUPP | 1.0000 | 0e+00 | 1.0000 | 1.0000 |
Figure 10.3: 95% confidence intervals of the specificity of CAZy family classification across all CAZy families per CAZy class, for each CAZyme classifier.
Figure 10.4: Scatter plot of overlaying a one-dimensional box-and-whisker plot of specificity for each CAZy family for each CAZyme classifier. Each CAZy family is represented as a single point on the plot.
Test for significant differences between the means of the tools using a one-way ANOVA.
## Df Sum Sq Mean Sq F value Pr(>F)
## Prediction_tool 4 5.100e-07 1.272e-07 1.006 0.403
## Residuals 1620 2.048e-04 1.264e-07The means are statistically significantly different, therefore, use a post hoc Turkey HSD test to determine between which tools the means are significantly difference.
## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistical_parameter ~ Prediction_tool, data = fam_subset_spec_all)
##
## $Prediction_tool
## diff lwr upr
## dbCAN_4:HMMER-dbCAN_4 -3.888500e-06 -7.977377e-05 7.199677e-05
## dbCAN_4:DIAMOND-dbCAN_4 -1.700975e-05 -9.330445e-05 5.928495e-05
## dbCAN_4:dbCAN-sub-dbCAN_4 -1.817296e-05 -9.417365e-05 5.782773e-05
## CUPP-dbCAN_4 3.093845e-05 -4.541601e-05 1.072929e-04
## dbCAN_4:DIAMOND-dbCAN_4:HMMER -1.312125e-05 -8.924291e-05 6.300040e-05
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER -1.428446e-05 -9.011143e-05 6.154251e-05
## CUPP-dbCAN_4:HMMER 3.482695e-05 -4.135460e-05 1.110085e-04
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND -1.163209e-06 -7.739992e-05 7.507350e-05
## CUPP-dbCAN_4:DIAMOND 4.794820e-05 -2.864119e-05 1.245376e-04
## CUPP-dbCAN_4:dbCAN-sub 4.911141e-05 -2.718511e-05 1.254079e-04
## p adj
## dbCAN_4:HMMER-dbCAN_4 0.9999138
## dbCAN_4:DIAMOND-dbCAN_4 0.9737306
## dbCAN_4:dbCAN-sub-dbCAN_4 0.9661090
## CUPP-dbCAN_4 0.8031741
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.9899508
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.9859450
## CUPP-dbCAN_4:HMMER 0.7228148
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND 0.9999993
## CUPP-dbCAN_4:DIAMOND 0.4282173
## CUPP-dbCAN_4:dbCAN-sub 0.3988456Now test for statistically significant differences between CAZy classes using a two-way ANOVA.
## Df Sum Sq Mean Sq F value Pr(>F)
## CAZy_class 5 1.616e-05 3.232e-06 27.402 <2e-16 ***
## Prediction_tool 4 5.000e-07 1.260e-07 1.068 0.371
## CAZy_class:Prediction_tool 20 5.600e-07 2.800e-08 0.237 1.000
## Residuals 1595 1.881e-04 1.180e-07
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1Statistically significant difference was detected so follow up with a Tukey test to determine if there are differences between specific groups.
## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistical_parameter ~ CAZy_class * Prediction_tool, data = fam_subset_spec_all)
##
## $`CAZy_class:Prediction_tool`
## diff lwr
## GT:dbCAN_4-GH:dbCAN_4 -8.289361e-05 -2.673711e-04
## PL:dbCAN_4-GH:dbCAN_4 2.836995e-05 -2.622707e-04
## CE:dbCAN_4-GH:dbCAN_4 -3.527867e-04 -6.761494e-04
## AA:dbCAN_4-GH:dbCAN_4 -3.121241e-04 -6.528820e-04
## CBM:dbCAN_4-GH:dbCAN_4 -5.988855e-05 -2.644599e-04
## GH:dbCAN_4:HMMER-GH:dbCAN_4 -5.418129e-06 -1.606952e-04
## GT:dbCAN_4:HMMER-GH:dbCAN_4 -9.247990e-05 -2.761852e-04
## PL:dbCAN_4:HMMER-GH:dbCAN_4 2.834376e-05 -2.622969e-04
## CE:dbCAN_4:HMMER-GH:dbCAN_4 -3.806808e-04 -7.040435e-04
## AA:dbCAN_4:HMMER-GH:dbCAN_4 -3.202315e-04 -6.609895e-04
## CBM:dbCAN_4:HMMER-GH:dbCAN_4 -4.667375e-05 -2.512451e-04
## GH:dbCAN_4:DIAMOND-GH:dbCAN_4 -3.281785e-05 -1.892326e-04
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4 -8.216354e-05 -2.666410e-04
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4 1.282445e-05 -2.778162e-04
## CE:dbCAN_4:DIAMOND-GH:dbCAN_4 -3.927674e-04 -7.244297e-04
## AA:dbCAN_4:DIAMOND-GH:dbCAN_4 -3.458398e-04 -6.865978e-04
## CBM:dbCAN_4:DIAMOND-GH:dbCAN_4 -5.422648e-05 -2.601138e-04
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4 -1.213742e-05 -1.676935e-04
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4 -1.013608e-04 -2.858382e-04
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4 2.838825e-05 -2.622524e-04
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4 -3.592661e-04 -6.826287e-04
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4 -3.271386e-04 -6.678965e-04
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4 -1.057825e-04 -3.103539e-04
## GH:CUPP-GH:dbCAN_4 -4.616972e-06 -1.610318e-04
## GT:CUPP-GH:dbCAN_4 -3.866359e-05 -2.239304e-04
## PL:CUPP-GH:dbCAN_4 3.897120e-05 -2.516694e-04
## CE:CUPP-GH:dbCAN_4 -3.345131e-04 -6.661754e-04
## AA:CUPP-GH:dbCAN_4 -2.826278e-04 -6.233857e-04
## CBM:CUPP-GH:dbCAN_4 4.969937e-05 -1.561879e-04
## PL:dbCAN_4-GT:dbCAN_4 1.112636e-04 -1.956863e-04
## CE:dbCAN_4-GT:dbCAN_4 -2.698931e-04 -6.079902e-04
## AA:dbCAN_4-GT:dbCAN_4 -2.292305e-04 -5.840011e-04
## CBM:dbCAN_4-GT:dbCAN_4 2.300506e-05 -2.041418e-04
## GH:dbCAN_4:HMMER-GT:dbCAN_4 7.747548e-05 -1.065278e-04
## GT:dbCAN_4:HMMER-GT:dbCAN_4 -9.586289e-06 -2.181382e-04
## PL:dbCAN_4:HMMER-GT:dbCAN_4 1.112374e-04 -1.957125e-04
## CE:dbCAN_4:HMMER-GT:dbCAN_4 -2.977872e-04 -6.358843e-04
## AA:dbCAN_4:HMMER-GT:dbCAN_4 -2.373379e-04 -5.921085e-04
## CBM:dbCAN_4:HMMER-GT:dbCAN_4 3.621987e-05 -1.909270e-04
## GH:dbCAN_4:DIAMOND-GT:dbCAN_4 5.007576e-05 -1.348886e-04
## GT:dbCAN_4:DIAMOND-GT:dbCAN_4 7.300717e-07 -2.085022e-04
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4 9.571807e-05 -2.112318e-04
## CE:dbCAN_4:DIAMOND-GT:dbCAN_4 -3.098738e-04 -6.559173e-04
## AA:dbCAN_4:DIAMOND-GT:dbCAN_4 -2.629462e-04 -6.177169e-04
## CBM:dbCAN_4:DIAMOND-GT:dbCAN_4 2.866713e-05 -1.996655e-04
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4 7.075620e-05 -1.134826e-04
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4 -1.846717e-05 -2.276995e-04
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4 1.112819e-04 -1.956680e-04
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4 -2.763725e-04 -6.144695e-04
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4 -2.442450e-04 -5.990156e-04
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4 -2.288887e-05 -2.500357e-04
## GH:CUPP-GT:dbCAN_4 7.827664e-05 -1.066877e-04
## GT:CUPP-GT:dbCAN_4 4.423003e-05 -1.656986e-04
## PL:CUPP-GT:dbCAN_4 1.218648e-04 -1.850850e-04
## CE:CUPP-GT:dbCAN_4 -2.516195e-04 -5.976630e-04
## AA:CUPP-GT:dbCAN_4 -1.997342e-04 -5.545048e-04
## CBM:CUPP-GT:dbCAN_4 1.325930e-04 -9.573968e-05
## CE:dbCAN_4-PL:dbCAN_4 -3.811567e-04 -7.870504e-04
## AA:dbCAN_4-PL:dbCAN_4 -3.404941e-04 -7.603777e-04
## CBM:dbCAN_4-PL:dbCAN_4 -8.825850e-05 -4.076888e-04
## GH:dbCAN_4:HMMER-PL:dbCAN_4 -3.378808e-05 -3.241280e-04
## GT:dbCAN_4:HMMER-PL:dbCAN_4 -1.208499e-04 -4.273363e-04
## PL:dbCAN_4:HMMER-PL:dbCAN_4 -2.619166e-08 -3.803659e-04
## CE:dbCAN_4:HMMER-PL:dbCAN_4 -4.090508e-04 -8.149444e-04
## AA:dbCAN_4:HMMER-PL:dbCAN_4 -3.486015e-04 -7.684851e-04
## CBM:dbCAN_4:HMMER-PL:dbCAN_4 -7.504370e-05 -3.944740e-04
## GH:dbCAN_4:DIAMOND-PL:dbCAN_4 -6.118780e-05 -3.521377e-04
## GT:dbCAN_4:DIAMOND-PL:dbCAN_4 -1.105335e-04 -4.174833e-04
## PL:dbCAN_4:DIAMOND-PL:dbCAN_4 -1.554550e-05 -3.958852e-04
## CE:dbCAN_4:DIAMOND-PL:dbCAN_4 -4.211374e-04 -8.336736e-04
## AA:dbCAN_4:DIAMOND-PL:dbCAN_4 -3.742098e-04 -7.940934e-04
## CBM:dbCAN_4:DIAMOND-PL:dbCAN_4 -8.259643e-05 -4.028711e-04
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4 -4.050737e-05 -3.309966e-04
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4 -1.297307e-04 -4.366806e-04
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4 1.829597e-08 -3.803214e-04
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4 -3.876360e-04 -7.935297e-04
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4 -3.555085e-04 -7.753921e-04
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4 -1.341524e-04 -4.535828e-04
## GH:CUPP-PL:dbCAN_4 -3.298692e-05 -3.239369e-04
## GT:CUPP-PL:dbCAN_4 -6.703354e-05 -3.744584e-04
## PL:CUPP-PL:dbCAN_4 1.060125e-05 -3.697384e-04
## CE:CUPP-PL:dbCAN_4 -3.628831e-04 -7.754193e-04
## AA:CUPP-PL:dbCAN_4 -3.109977e-04 -7.308813e-04
## CBM:CUPP-PL:dbCAN_4 2.132942e-05 -2.989452e-04
## AA:dbCAN_4-CE:dbCAN_4 4.066262e-05 -4.025006e-04
## CBM:dbCAN_4-CE:dbCAN_4 2.928982e-04 -5.656879e-05
## GH:dbCAN_4:HMMER-CE:dbCAN_4 3.473686e-04 2.427622e-05
## GT:dbCAN_4:HMMER-CE:dbCAN_4 2.603068e-04 -7.736959e-05
## PL:dbCAN_4:HMMER-CE:dbCAN_4 3.811305e-04 -2.476320e-05
## CE:dbCAN_4:HMMER-CE:dbCAN_4 -2.789408e-05 -4.578256e-04
## AA:dbCAN_4:HMMER-CE:dbCAN_4 3.255520e-05 -4.106081e-04
## CBM:dbCAN_4:HMMER-CE:dbCAN_4 3.061130e-04 -4.335398e-05
## GH:dbCAN_4:DIAMOND-CE:dbCAN_4 3.199689e-04 -3.671808e-06
## GT:dbCAN_4:DIAMOND-CE:dbCAN_4 2.706232e-04 -6.747389e-05
## PL:dbCAN_4:DIAMOND-CE:dbCAN_4 3.656112e-04 -4.028250e-05
## CE:dbCAN_4:DIAMOND-CE:dbCAN_4 -3.998068e-05 -4.761889e-04
## AA:dbCAN_4:DIAMOND-CE:dbCAN_4 6.946894e-06 -4.362164e-04
## CBM:dbCAN_4:DIAMOND-CE:dbCAN_4 2.985602e-04 -5.167864e-05
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4 3.406493e-04 1.742275e-05
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4 2.514259e-04 -8.667113e-05
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4 3.811750e-04 -2.471871e-05
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4 -6.479344e-06 -4.364109e-04
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4 2.564815e-05 -4.175151e-04
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4 2.470042e-04 -1.024627e-04
## GH:CUPP-CE:dbCAN_4 3.481698e-04 2.452907e-05
## GT:CUPP-CE:dbCAN_4 3.141231e-04 -2.440527e-05
## PL:CUPP-CE:dbCAN_4 3.917579e-04 -1.413576e-05
## CE:CUPP-CE:dbCAN_4 1.827362e-05 -4.179346e-04
## AA:CUPP-CE:dbCAN_4 7.015896e-05 -3.730043e-04
## CBM:CUPP-CE:dbCAN_4 4.024861e-04 5.224721e-05
## CBM:dbCAN_4-AA:dbCAN_4 2.522356e-04 -1.133868e-04
## GH:dbCAN_4:HMMER-AA:dbCAN_4 3.067060e-04 -3.379549e-05
## GT:dbCAN_4:HMMER-AA:dbCAN_4 2.196442e-04 -1.347256e-04
## PL:dbCAN_4:HMMER-AA:dbCAN_4 3.404679e-04 -7.941575e-05
## CE:dbCAN_4:HMMER-AA:dbCAN_4 -6.855670e-05 -5.117200e-04
## AA:dbCAN_4:HMMER-AA:dbCAN_4 -8.107420e-06 -4.641187e-04
## CBM:dbCAN_4:HMMER-AA:dbCAN_4 2.654504e-04 -1.001720e-04
## GH:dbCAN_4:DIAMOND-AA:dbCAN_4 2.793063e-04 -6.171553e-05
## GT:dbCAN_4:DIAMOND-AA:dbCAN_4 2.299606e-04 -1.248101e-04
## PL:dbCAN_4:DIAMOND-AA:dbCAN_4 3.249486e-04 -9.493506e-05
## CE:dbCAN_4:DIAMOND-AA:dbCAN_4 -8.064330e-05 -5.298984e-04
## AA:dbCAN_4:DIAMOND-AA:dbCAN_4 -3.371572e-05 -4.897270e-04
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4 2.578976e-04 -1.084626e-04
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4 2.999867e-04 -4.064210e-05
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4 2.107633e-04 -1.440073e-04
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4 3.405124e-04 -7.937126e-05
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4 -4.714196e-05 -4.903052e-04
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4 -1.501447e-05 -4.710257e-04
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4 2.063416e-04 -1.592808e-04
## GH:CUPP-AA:dbCAN_4 3.075071e-04 -3.351466e-05
## GT:CUPP-AA:dbCAN_4 2.734605e-04 -8.172120e-05
## PL:CUPP-AA:dbCAN_4 3.510953e-04 -6.878831e-05
## CE:CUPP-AA:dbCAN_4 -2.238900e-05 -4.716441e-04
## AA:CUPP-AA:dbCAN_4 2.949634e-05 -4.265149e-04
## CBM:CUPP-AA:dbCAN_4 3.618235e-04 -4.536794e-06
## GH:dbCAN_4:HMMER-CBM:dbCAN_4 5.447042e-05 -1.496735e-04
## GT:dbCAN_4:HMMER-CBM:dbCAN_4 -3.259135e-05 -2.591116e-04
## PL:dbCAN_4:HMMER-CBM:dbCAN_4 8.823231e-05 -2.311980e-04
## CE:dbCAN_4:HMMER-CBM:dbCAN_4 -3.207923e-04 -6.702592e-04
## AA:dbCAN_4:HMMER-CBM:dbCAN_4 -2.603430e-04 -6.259654e-04
## CBM:dbCAN_4:HMMER-CBM:dbCAN_4 1.321481e-05 -2.305335e-04
## GH:dbCAN_4:DIAMOND-CBM:dbCAN_4 2.707070e-05 -1.779399e-04
## GT:dbCAN_4:DIAMOND-CBM:dbCAN_4 -2.227499e-05 -2.494218e-04
## PL:dbCAN_4:DIAMOND-CBM:dbCAN_4 7.271300e-05 -2.467173e-04
## CE:dbCAN_4:DIAMOND-CBM:dbCAN_4 -3.328789e-04 -6.900394e-04
## AA:dbCAN_4:DIAMOND-CBM:dbCAN_4 -2.859513e-04 -6.515737e-04
## CBM:dbCAN_4:DIAMOND-CBM:dbCAN_4 5.662073e-06 -2.391916e-04
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 4.775114e-05 -1.566051e-04
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 -4.147223e-05 -2.686191e-04
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 8.827680e-05 -2.311535e-04
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 -2.993775e-04 -6.488445e-04
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 -2.672500e-04 -6.328724e-04
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 -4.589393e-05 -2.896422e-04
## GH:CUPP-CBM:dbCAN_4 5.527158e-05 -1.497390e-04
## GT:CUPP-CBM:dbCAN_4 2.122497e-05 -2.065634e-04
## PL:CUPP-CBM:dbCAN_4 9.885975e-05 -2.205706e-04
## CE:CUPP-CBM:dbCAN_4 -2.746246e-04 -6.317851e-04
## AA:CUPP-CBM:dbCAN_4 -2.227392e-04 -5.883616e-04
## CBM:CUPP-CBM:dbCAN_4 1.095879e-04 -1.352658e-04
## GT:dbCAN_4:HMMER-GH:dbCAN_4:HMMER -8.706177e-05 -2.702910e-04
## PL:dbCAN_4:HMMER-GH:dbCAN_4:HMMER 3.376189e-05 -2.565780e-04
## CE:dbCAN_4:HMMER-GH:dbCAN_4:HMMER -3.752627e-04 -6.983551e-04
## AA:dbCAN_4:HMMER-GH:dbCAN_4:HMMER -3.148134e-04 -6.553149e-04
## CBM:dbCAN_4:HMMER-GH:dbCAN_4:HMMER -4.125562e-05 -2.453995e-04
## GH:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER -2.739972e-05 -1.832550e-04
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER -7.674541e-05 -2.607487e-04
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 1.824258e-05 -2.720973e-04
## CE:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER -3.873493e-04 -7.187481e-04
## AA:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER -3.404217e-04 -6.809232e-04
## CBM:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER -4.880835e-05 -2.542709e-04
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER -6.719287e-06 -1.617128e-04
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER -9.594265e-05 -2.799459e-04
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 3.380638e-05 -2.565335e-04
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER -3.538479e-04 -6.769403e-04
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER -3.217204e-04 -6.622219e-04
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER -1.003644e-04 -3.045083e-04
## GH:CUPP-GH:dbCAN_4:HMMER 8.011568e-07 -1.550541e-04
## GT:CUPP-GH:dbCAN_4:HMMER -3.324546e-05 -2.180401e-04
## PL:CUPP-GH:dbCAN_4:HMMER 4.438933e-05 -2.459506e-04
## CE:CUPP-GH:dbCAN_4:HMMER -3.290950e-04 -6.604938e-04
## AA:CUPP-GH:dbCAN_4:HMMER -2.772096e-04 -6.177111e-04
## CBM:CUPP-GH:dbCAN_4:HMMER 5.511750e-05 -1.503450e-04
## PL:dbCAN_4:HMMER-GT:dbCAN_4:HMMER 1.208237e-04 -1.856628e-04
## CE:dbCAN_4:HMMER-GT:dbCAN_4:HMMER -2.882009e-04 -6.258773e-04
## AA:dbCAN_4:HMMER-GT:dbCAN_4:HMMER -2.277516e-04 -5.821214e-04
## CBM:dbCAN_4:HMMER-GT:dbCAN_4:HMMER 4.580616e-05 -1.807141e-04
## GH:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 5.966205e-05 -1.245323e-04
## GT:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 1.031636e-05 -1.982355e-04
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 1.053044e-04 -2.011821e-04
## CE:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER -3.002875e-04 -6.459201e-04
## AA:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER -2.533599e-04 -6.077297e-04
## CBM:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 3.825342e-05 -1.894559e-04
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 8.034249e-05 -1.031232e-04
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER -8.880879e-06 -2.174328e-04
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 1.208682e-04 -1.856183e-04
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER -2.667862e-04 -6.044626e-04
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER -2.346587e-04 -5.890284e-04
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER -1.330258e-05 -2.398228e-04
## GH:CUPP-GT:dbCAN_4:HMMER 8.786293e-05 -9.633138e-05
## GT:CUPP-GT:dbCAN_4:HMMER 5.381632e-05 -1.554341e-04
## PL:CUPP-GT:dbCAN_4:HMMER 1.314511e-04 -1.750353e-04
## CE:CUPP-GT:dbCAN_4:HMMER -2.420332e-04 -5.876658e-04
## AA:CUPP-GT:dbCAN_4:HMMER -1.901479e-04 -5.445176e-04
## CBM:CUPP-GT:dbCAN_4:HMMER 1.421793e-04 -8.553004e-05
## CE:dbCAN_4:HMMER-PL:dbCAN_4:HMMER -4.090246e-04 -8.149183e-04
## AA:dbCAN_4:HMMER-PL:dbCAN_4:HMMER -3.485753e-04 -7.684589e-04
## CBM:dbCAN_4:HMMER-PL:dbCAN_4:HMMER -7.501751e-05 -3.944478e-04
## GH:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER -6.116161e-05 -3.521116e-04
## GT:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER -1.105073e-04 -4.174571e-04
## PL:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER -1.551931e-05 -3.958590e-04
## CE:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER -4.211112e-04 -8.336475e-04
## AA:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER -3.741836e-04 -7.940672e-04
## CBM:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER -8.257024e-05 -4.028449e-04
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER -4.048118e-05 -3.309704e-04
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER -1.297045e-04 -4.366544e-04
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 4.448763e-08 -3.802952e-04
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER -3.876098e-04 -7.935035e-04
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER -3.554823e-04 -7.753660e-04
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER -1.341262e-04 -4.535566e-04
## GH:CUPP-PL:dbCAN_4:HMMER -3.296073e-05 -3.239107e-04
## GT:CUPP-PL:dbCAN_4:HMMER -6.700735e-05 -3.744322e-04
## PL:CUPP-PL:dbCAN_4:HMMER 1.062744e-05 -3.697122e-04
## CE:CUPP-PL:dbCAN_4:HMMER -3.628569e-04 -7.753932e-04
## AA:CUPP-PL:dbCAN_4:HMMER -3.109715e-04 -7.308551e-04
## CBM:CUPP-PL:dbCAN_4:HMMER 2.135561e-05 -2.989190e-04
## AA:dbCAN_4:HMMER-CE:dbCAN_4:HMMER 6.044928e-05 -3.827140e-04
## CBM:dbCAN_4:HMMER-CE:dbCAN_4:HMMER 3.340071e-04 -1.545990e-05
## GH:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 3.478630e-04 2.422227e-05
## GT:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 2.985173e-04 -3.957981e-05
## PL:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 3.935053e-04 -1.238842e-05
## CE:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER -1.208660e-05 -4.482948e-04
## AA:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 3.484098e-05 -4.083223e-04
## CBM:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 3.264543e-04 -2.378456e-05
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 3.685434e-04 4.531684e-05
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 2.793200e-04 -5.877705e-05
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 4.090691e-04 3.175374e-06
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 2.141474e-05 -4.085168e-04
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 5.354223e-05 -3.896210e-04
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 2.748983e-04 -7.456864e-05
## GH:CUPP-CE:dbCAN_4:HMMER 3.760638e-04 5.242315e-05
## GT:CUPP-CE:dbCAN_4:HMMER 3.420172e-04 3.488811e-06
## PL:CUPP-CE:dbCAN_4:HMMER 4.196520e-04 1.375832e-05
## CE:CUPP-CE:dbCAN_4:HMMER 4.616770e-05 -3.900405e-04
## AA:CUPP-CE:dbCAN_4:HMMER 9.805304e-05 -3.451102e-04
## CBM:CUPP-CE:dbCAN_4:HMMER 4.303802e-04 8.014129e-05
## CBM:dbCAN_4:HMMER-AA:dbCAN_4:HMMER 2.735578e-04 -9.206460e-05
## GH:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 2.874137e-04 -5.360811e-05
## GT:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 2.380680e-04 -1.167026e-04
## PL:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 3.330560e-04 -8.682764e-05
## CE:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER -7.253588e-05 -5.217910e-04
## AA:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER -2.560830e-05 -4.816195e-04
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 2.660051e-04 -1.003552e-04
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 3.080941e-04 -3.253468e-05
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 2.188707e-04 -1.358999e-04
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 3.486198e-04 -7.126384e-05
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER -3.903454e-05 -4.821978e-04
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER -6.907047e-06 -4.629183e-04
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 2.144490e-04 -1.511733e-04
## GH:CUPP-AA:dbCAN_4:HMMER 3.156146e-04 -2.540724e-05
## GT:CUPP-AA:dbCAN_4:HMMER 2.815679e-04 -7.361378e-05
## PL:CUPP-AA:dbCAN_4:HMMER 3.592027e-04 -6.068089e-05
## CE:CUPP-AA:dbCAN_4:HMMER -1.428158e-05 -4.635367e-04
## AA:CUPP-AA:dbCAN_4:HMMER 3.760376e-05 -4.184075e-04
## CBM:CUPP-AA:dbCAN_4:HMMER 3.699309e-04 3.570626e-06
## GH:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 1.385590e-05 -1.911547e-04
## GT:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER -3.548979e-05 -2.626366e-04
## PL:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 5.949820e-05 -2.599321e-04
## CE:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER -3.460937e-04 -7.032542e-04
## AA:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER -2.991661e-04 -6.647885e-04
## CBM:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER -7.552732e-06 -2.524064e-04
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 3.453633e-05 -1.698199e-04
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER -5.468703e-05 -2.818339e-04
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 7.506199e-05 -2.443683e-04
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER -3.125923e-04 -6.620593e-04
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER -2.804648e-04 -6.460872e-04
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER -5.910874e-05 -3.028570e-04
## GH:CUPP-CBM:dbCAN_4:HMMER 4.205678e-05 -1.629538e-04
## GT:CUPP-CBM:dbCAN_4:HMMER 8.010161e-06 -2.197782e-04
## PL:CUPP-CBM:dbCAN_4:HMMER 8.564495e-05 -2.337854e-04
## CE:CUPP-CBM:dbCAN_4:HMMER -2.878394e-04 -6.449999e-04
## AA:CUPP-CBM:dbCAN_4:HMMER -2.359540e-04 -6.015764e-04
## CBM:CUPP-CBM:dbCAN_4:HMMER 9.637312e-05 -1.484806e-04
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND -4.934569e-05 -2.343101e-04
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND 4.564230e-05 -2.453076e-04
## CE:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND -3.599496e-04 -6.918830e-04
## AA:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND -3.130220e-04 -6.540438e-04
## CBM:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND -2.140863e-05 -2.277323e-04
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 2.068043e-05 -1.354528e-04
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND -6.854293e-05 -2.535073e-04
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 6.120610e-05 -2.297438e-04
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND -3.264482e-04 -6.500889e-04
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND -2.943207e-04 -6.353425e-04
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND -7.296464e-05 -2.779752e-04
## GH:CUPP-GH:dbCAN_4:DIAMOND 2.820088e-05 -1.287879e-04
## GT:CUPP-GH:dbCAN_4:DIAMOND -5.845737e-06 -1.915974e-04
## PL:CUPP-GH:dbCAN_4:DIAMOND 7.178905e-05 -2.191609e-04
## CE:CUPP-GH:dbCAN_4:DIAMOND -3.016953e-04 -6.336287e-04
## AA:CUPP-GH:dbCAN_4:DIAMOND -2.498099e-04 -5.908317e-04
## CBM:CUPP-GH:dbCAN_4:DIAMOND 8.251722e-05 -1.238065e-04
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4:DIAMOND 9.498799e-05 -2.119619e-04
## CE:dbCAN_4:DIAMOND-GT:dbCAN_4:DIAMOND -3.106039e-04 -6.566474e-04
## AA:dbCAN_4:DIAMOND-GT:dbCAN_4:DIAMOND -2.636763e-04 -6.184469e-04
## CBM:dbCAN_4:DIAMOND-GT:dbCAN_4:DIAMOND 2.793706e-05 -2.003956e-04
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 7.002613e-05 -1.142127e-04
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND -1.919724e-05 -2.284295e-04
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 1.105518e-04 -1.963981e-04
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND -2.771025e-04 -6.151996e-04
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND -2.449750e-04 -5.997457e-04
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND -2.361894e-05 -2.507658e-04
## GH:CUPP-GT:dbCAN_4:DIAMOND 7.754657e-05 -1.074178e-04
## GT:CUPP-GT:dbCAN_4:DIAMOND 4.349996e-05 -1.664286e-04
## PL:CUPP-GT:dbCAN_4:DIAMOND 1.211347e-04 -1.858151e-04
## CE:CUPP-GT:dbCAN_4:DIAMOND -2.523496e-04 -5.983931e-04
## AA:CUPP-GT:dbCAN_4:DIAMOND -2.004642e-04 -5.552349e-04
## CBM:CUPP-GT:dbCAN_4:DIAMOND 1.318629e-04 -9.646975e-05
## CE:dbCAN_4:DIAMOND-PL:dbCAN_4:DIAMOND -4.055919e-04 -8.181281e-04
## AA:dbCAN_4:DIAMOND-PL:dbCAN_4:DIAMOND -3.586643e-04 -7.785479e-04
## CBM:dbCAN_4:DIAMOND-PL:dbCAN_4:DIAMOND -6.705093e-05 -3.873256e-04
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -2.496187e-05 -3.154511e-04
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -1.141852e-04 -4.211351e-04
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 1.556380e-05 -3.647759e-04
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -3.720905e-04 -7.779842e-04
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -3.399630e-04 -7.598466e-04
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -1.186069e-04 -4.380373e-04
## GH:CUPP-PL:dbCAN_4:DIAMOND -1.744142e-05 -3.083914e-04
## GT:CUPP-PL:dbCAN_4:DIAMOND -5.148804e-05 -3.589129e-04
## PL:CUPP-PL:dbCAN_4:DIAMOND 2.614675e-05 -3.541929e-04
## CE:CUPP-PL:dbCAN_4:DIAMOND -3.473376e-04 -7.598738e-04
## AA:CUPP-PL:dbCAN_4:DIAMOND -2.954522e-04 -7.153358e-04
## CBM:CUPP-PL:dbCAN_4:DIAMOND 3.687492e-05 -2.833997e-04
## AA:dbCAN_4:DIAMOND-CE:dbCAN_4:DIAMOND 4.692758e-05 -4.023276e-04
## CBM:dbCAN_4:DIAMOND-CE:dbCAN_4:DIAMOND 3.385409e-04 -1.937496e-05
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 3.806300e-04 4.910034e-05
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 2.914066e-04 -5.463692e-05
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 4.211557e-04 8.619375e-06
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 3.350134e-05 -4.027069e-04
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 6.562883e-05 -3.836263e-04
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 2.869849e-04 -7.017563e-05
## GH:CUPP-CE:dbCAN_4:DIAMOND 3.881504e-04 5.621702e-05
## GT:CUPP-CE:dbCAN_4:DIAMOND 3.541038e-04 7.638835e-06
## PL:CUPP-CE:dbCAN_4:DIAMOND 4.317386e-04 1.920233e-05
## CE:CUPP-CE:dbCAN_4:DIAMOND 5.825430e-05 -3.841416e-04
## AA:CUPP-CE:dbCAN_4:DIAMOND 1.101396e-04 -3.391155e-04
## CBM:CUPP-CE:dbCAN_4:DIAMOND 4.424668e-04 8.455089e-05
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND 2.916134e-04 -7.474692e-05
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 3.337024e-04 -6.926379e-06
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 2.444791e-04 -1.102916e-04
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 3.742281e-04 -4.565554e-05
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND -1.342624e-05 -4.565895e-04
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 1.870126e-05 -4.373100e-04
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 2.400573e-04 -1.255650e-04
## GH:CUPP-AA:dbCAN_4:DIAMOND 3.412229e-04 2.010687e-07
## GT:CUPP-AA:dbCAN_4:DIAMOND 3.071762e-04 -4.800547e-05
## PL:CUPP-AA:dbCAN_4:DIAMOND 3.848110e-04 -3.507259e-05
## CE:CUPP-AA:dbCAN_4:DIAMOND 1.132672e-05 -4.379284e-04
## AA:CUPP-AA:dbCAN_4:DIAMOND 6.321207e-05 -3.927992e-04
## CBM:CUPP-AA:dbCAN_4:DIAMOND 3.955392e-04 2.917893e-05
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 4.208906e-05 -1.635844e-04
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND -4.713430e-05 -2.754670e-04
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 8.261473e-05 -2.376599e-04
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND -3.050396e-04 -6.552785e-04
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND -2.729121e-04 -6.392724e-04
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND -5.155601e-05 -2.964097e-04
## GH:CUPP-CBM:dbCAN_4:DIAMOND 4.960951e-05 -1.567142e-04
## GT:CUPP-CBM:dbCAN_4:DIAMOND 1.556289e-05 -2.134080e-04
## PL:CUPP-CBM:dbCAN_4:DIAMOND 9.319768e-05 -2.270770e-04
## CE:CUPP-CBM:dbCAN_4:DIAMOND -2.802866e-04 -6.382025e-04
## AA:CUPP-CBM:dbCAN_4:DIAMOND -2.284013e-04 -5.947616e-04
## CBM:CUPP-CBM:dbCAN_4:DIAMOND 1.039258e-04 -1.420283e-04
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub -8.922337e-05 -2.734622e-04
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub 4.052566e-05 -2.499636e-04
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub -3.471287e-04 -6.703552e-04
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub -3.150012e-04 -6.556300e-04
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub -9.364507e-05 -2.980013e-04
## GH:CUPP-GH:dbCAN_4:dbCAN-sub 7.520444e-06 -1.486128e-04
## GT:CUPP-GH:dbCAN_4:dbCAN-sub -2.652617e-05 -2.115553e-04
## PL:CUPP-GH:dbCAN_4:dbCAN-sub 5.110861e-05 -2.393806e-04
## CE:CUPP-GH:dbCAN_4:dbCAN-sub -3.223757e-04 -6.539053e-04
## AA:CUPP-GH:dbCAN_4:dbCAN-sub -2.704904e-04 -6.111191e-04
## CBM:CUPP-GH:dbCAN_4:dbCAN-sub 6.183679e-05 -1.438367e-04
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:dbCAN-sub 1.297490e-04 -1.772008e-04
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4:dbCAN-sub -2.579053e-04 -5.960024e-04
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4:dbCAN-sub -2.257778e-04 -5.805484e-04
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4:dbCAN-sub -4.421704e-06 -2.315685e-04
## GH:CUPP-GT:dbCAN_4:dbCAN-sub 9.674381e-05 -8.822056e-05
## GT:CUPP-GT:dbCAN_4:dbCAN-sub 6.269720e-05 -1.472314e-04
## PL:CUPP-GT:dbCAN_4:dbCAN-sub 1.403320e-04 -1.666179e-04
## CE:CUPP-GT:dbCAN_4:dbCAN-sub -2.331523e-04 -5.791959e-04
## AA:CUPP-GT:dbCAN_4:dbCAN-sub -1.812670e-04 -5.360376e-04
## CBM:CUPP-GT:dbCAN_4:dbCAN-sub 1.510602e-04 -7.727251e-05
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4:dbCAN-sub -3.876543e-04 -7.935480e-04
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4:dbCAN-sub -3.555268e-04 -7.754104e-04
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4:dbCAN-sub -1.341707e-04 -4.536011e-04
## GH:CUPP-PL:dbCAN_4:dbCAN-sub -3.300522e-05 -3.239552e-04
## GT:CUPP-PL:dbCAN_4:dbCAN-sub -6.705183e-05 -3.744767e-04
## PL:CUPP-PL:dbCAN_4:dbCAN-sub 1.058295e-05 -3.697567e-04
## CE:CUPP-PL:dbCAN_4:dbCAN-sub -3.629014e-04 -7.754376e-04
## AA:CUPP-PL:dbCAN_4:dbCAN-sub -3.110160e-04 -7.308996e-04
## CBM:CUPP-PL:dbCAN_4:dbCAN-sub 2.131112e-05 -2.989635e-04
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4:dbCAN-sub 3.212750e-05 -4.110358e-04
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4:dbCAN-sub 2.534836e-04 -9.598338e-05
## GH:CUPP-CE:dbCAN_4:dbCAN-sub 3.546491e-04 3.100841e-05
## GT:CUPP-CE:dbCAN_4:dbCAN-sub 3.206025e-04 -1.792593e-05
## PL:CUPP-CE:dbCAN_4:dbCAN-sub 3.982373e-04 -7.656414e-06
## CE:CUPP-CE:dbCAN_4:dbCAN-sub 2.475296e-05 -4.114553e-04
## AA:CUPP-CE:dbCAN_4:dbCAN-sub 7.663831e-05 -3.665250e-04
## CBM:CUPP-CE:dbCAN_4:dbCAN-sub 4.089654e-04 5.872655e-05
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub 2.213561e-04 -1.442663e-04
## GH:CUPP-AA:dbCAN_4:dbCAN-sub 3.225216e-04 -1.850019e-05
## GT:CUPP-AA:dbCAN_4:dbCAN-sub 2.884750e-04 -6.670673e-05
## PL:CUPP-AA:dbCAN_4:dbCAN-sub 3.661098e-04 -5.377384e-05
## CE:CUPP-AA:dbCAN_4:dbCAN-sub -7.374533e-06 -4.566297e-04
## AA:CUPP-AA:dbCAN_4:dbCAN-sub 4.451081e-05 -4.115004e-04
## CBM:CUPP-AA:dbCAN_4:dbCAN-sub 3.768379e-04 1.047767e-05
## GH:CUPP-CBM:dbCAN_4:dbCAN-sub 1.011655e-04 -1.038451e-04
## GT:CUPP-CBM:dbCAN_4:dbCAN-sub 6.711890e-05 -1.606695e-04
## PL:CUPP-CBM:dbCAN_4:dbCAN-sub 1.447537e-04 -1.746766e-04
## CE:CUPP-CBM:dbCAN_4:dbCAN-sub -2.287306e-04 -5.858912e-04
## AA:CUPP-CBM:dbCAN_4:dbCAN-sub -1.768453e-04 -5.424677e-04
## CBM:CUPP-CBM:dbCAN_4:dbCAN-sub 1.554819e-04 -8.937184e-05
## GT:CUPP-GH:CUPP -3.404661e-05 -2.197983e-04
## PL:CUPP-GH:CUPP 4.358817e-05 -2.473618e-04
## CE:CUPP-GH:CUPP -3.298961e-04 -6.618296e-04
## AA:CUPP-GH:CUPP -2.780108e-04 -6.190326e-04
## CBM:CUPP-GH:CUPP 5.431634e-05 -1.520074e-04
## PL:CUPP-GT:CUPP 7.763478e-05 -2.297901e-04
## CE:CUPP-GT:CUPP -2.958495e-04 -6.423145e-04
## AA:CUPP-GT:CUPP -2.439642e-04 -5.991459e-04
## CBM:CUPP-GT:CUPP 8.836296e-05 -1.406079e-04
## CE:CUPP-PL:CUPP -3.734843e-04 -7.860206e-04
## AA:CUPP-PL:CUPP -3.215990e-04 -7.414826e-04
## CBM:CUPP-PL:CUPP 1.072817e-05 -3.095465e-04
## AA:CUPP-CE:CUPP 5.188534e-05 -3.973698e-04
## CBM:CUPP-CE:CUPP 3.842125e-04 2.629659e-05
## CBM:CUPP-AA:CUPP 3.323271e-04 -3.403314e-05
## upr p adj
## GT:dbCAN_4-GH:dbCAN_4 1.015838e-04 0.9983142
## PL:dbCAN_4-GH:dbCAN_4 3.190106e-04 1.0000000
## CE:dbCAN_4-GH:dbCAN_4 -2.942408e-05 0.0144319
## AA:dbCAN_4-GH:dbCAN_4 2.863382e-05 0.1335271
## CBM:dbCAN_4-GH:dbCAN_4 1.446828e-04 0.9999997
## GH:dbCAN_4:HMMER-GH:dbCAN_4 1.498590e-04 1.0000000
## GT:dbCAN_4:HMMER-GH:dbCAN_4 9.122543e-05 0.9901187
## PL:dbCAN_4:HMMER-GH:dbCAN_4 3.189844e-04 1.0000000
## CE:dbCAN_4:HMMER-GH:dbCAN_4 -5.731817e-05 0.0038197
## AA:dbCAN_4:HMMER-GH:dbCAN_4 2.052640e-05 0.1028833
## CBM:dbCAN_4:HMMER-GH:dbCAN_4 1.578976e-04 1.0000000
## GH:dbCAN_4:DIAMOND-GH:dbCAN_4 1.235969e-04 1.0000000
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4 1.023139e-04 0.9985472
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4 3.034651e-04 1.0000000
## CE:dbCAN_4:DIAMOND-GH:dbCAN_4 -6.110508e-05 0.0034097
## AA:dbCAN_4:DIAMOND-GH:dbCAN_4 -5.081901e-06 0.0412836
## CBM:dbCAN_4:DIAMOND-GH:dbCAN_4 1.516608e-04 1.0000000
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4 1.434187e-04 1.0000000
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4 8.311666e-05 0.9681642
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4 3.190289e-04 1.0000000
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4 -3.590343e-05 0.0107312
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4 1.361936e-05 0.0814833
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4 9.878890e-05 0.9855955
## GH:CUPP-GH:dbCAN_4 1.517978e-04 1.0000000
## GT:CUPP-GH:dbCAN_4 1.466032e-04 1.0000000
## PL:CUPP-GH:dbCAN_4 3.296118e-04 1.0000000
## CE:CUPP-GH:dbCAN_4 -2.850777e-06 0.0448006
## AA:CUPP-GH:dbCAN_4 5.813017e-05 0.3035502
## CBM:CUPP-GH:dbCAN_4 2.555867e-04 1.0000000
## PL:dbCAN_4-GT:dbCAN_4 4.182134e-04 0.9999695
## CE:dbCAN_4-GT:dbCAN_4 6.820396e-05 0.3870614
## AA:dbCAN_4-GT:dbCAN_4 1.255401e-04 0.8274674
## CBM:dbCAN_4-GT:dbCAN_4 2.501519e-04 1.0000000
## GH:dbCAN_4:HMMER-GT:dbCAN_4 2.614788e-04 0.9994545
## GT:dbCAN_4:HMMER-GT:dbCAN_4 1.989656e-04 1.0000000
## PL:dbCAN_4:HMMER-GT:dbCAN_4 4.181872e-04 0.9999696
## CE:dbCAN_4:HMMER-GT:dbCAN_4 4.030988e-05 0.1911504
## AA:dbCAN_4:HMMER-GT:dbCAN_4 1.174327e-04 0.7718310
## CBM:dbCAN_4:HMMER-GT:dbCAN_4 2.633667e-04 1.0000000
## GH:dbCAN_4:DIAMOND-GT:dbCAN_4 2.350401e-04 1.0000000
## GT:dbCAN_4:DIAMOND-GT:dbCAN_4 2.099624e-04 1.0000000
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4 4.026679e-04 0.9999988
## CE:dbCAN_4:DIAMOND-GT:dbCAN_4 3.616975e-05 0.1652072
## AA:dbCAN_4:DIAMOND-GT:dbCAN_4 9.182441e-05 0.5596300
## CBM:dbCAN_4:DIAMOND-GT:dbCAN_4 2.569998e-04 1.0000000
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4 2.549950e-04 0.9999030
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4 1.907651e-04 1.0000000
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4 4.182317e-04 0.9999693
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4 6.172462e-05 0.3344307
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4 1.105257e-04 0.7188432
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4 2.042580e-04 1.0000000
## GH:CUPP-GT:dbCAN_4 2.632410e-04 0.9994025
## GT:CUPP-GT:dbCAN_4 2.541586e-04 1.0000000
## PL:CUPP-GT:dbCAN_4 4.288147e-04 0.9998159
## CE:CUPP-GT:dbCAN_4 9.442405e-05 0.6032762
## AA:CUPP-GT:dbCAN_4 1.550365e-04 0.9572744
## CBM:CUPP-GT:dbCAN_4 3.609256e-04 0.9391445
## CE:dbCAN_4-PL:dbCAN_4 2.473700e-05 0.1037047
## AA:dbCAN_4-PL:dbCAN_4 7.938956e-05 0.3518900
## CBM:dbCAN_4-PL:dbCAN_4 2.311718e-04 0.9999999
## GH:dbCAN_4:HMMER-PL:dbCAN_4 2.565518e-04 1.0000000
## GT:dbCAN_4:HMMER-PL:dbCAN_4 1.856366e-04 0.9998385
## PL:dbCAN_4:HMMER-PL:dbCAN_4 3.803135e-04 1.0000000
## CE:dbCAN_4:HMMER-PL:dbCAN_4 -3.157078e-06 0.0452740
## AA:dbCAN_4:HMMER-PL:dbCAN_4 7.128214e-05 0.3014853
## CBM:dbCAN_4:HMMER-PL:dbCAN_4 2.443866e-04 1.0000000
## GH:dbCAN_4:DIAMOND-PL:dbCAN_4 2.297621e-04 1.0000000
## GT:dbCAN_4:DIAMOND-PL:dbCAN_4 1.964164e-04 0.9999733
## PL:dbCAN_4:DIAMOND-PL:dbCAN_4 3.647942e-04 1.0000000
## CE:dbCAN_4:DIAMOND-PL:dbCAN_4 -8.601079e-06 0.0382008
## AA:dbCAN_4:DIAMOND-PL:dbCAN_4 4.567383e-05 0.1724313
## CBM:dbCAN_4:DIAMOND-PL:dbCAN_4 2.376782e-04 1.0000000
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4 2.499818e-04 1.0000000
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4 1.772191e-04 0.9994164
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4 3.803580e-04 1.0000000
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4 1.825766e-05 0.0864017
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4 6.437509e-05 0.2620104
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4 1.852779e-04 0.9994791
## GH:CUPP-PL:dbCAN_4 2.579630e-04 1.0000000
## GT:CUPP-PL:dbCAN_4 2.403914e-04 1.0000000
## PL:CUPP-PL:dbCAN_4 3.909409e-04 1.0000000
## CE:CUPP-PL:dbCAN_4 4.965322e-05 0.1932682
## AA:CUPP-PL:dbCAN_4 1.088859e-04 0.5611770
## CBM:CUPP-PL:dbCAN_4 3.416041e-04 1.0000000
## AA:dbCAN_4-CE:dbCAN_4 4.838259e-04 1.0000000
## CBM:dbCAN_4-CE:dbCAN_4 6.423651e-04 0.2821246
## GH:dbCAN_4:HMMER-CE:dbCAN_4 6.704610e-04 0.0181435
## GT:dbCAN_4:HMMER-CE:dbCAN_4 5.979832e-04 0.4678221
## PL:dbCAN_4:HMMER-CE:dbCAN_4 7.870242e-04 0.1037800
## CE:dbCAN_4:HMMER-CE:dbCAN_4 4.020374e-04 1.0000000
## AA:dbCAN_4:HMMER-CE:dbCAN_4 4.757185e-04 1.0000000
## CBM:dbCAN_4:HMMER-CE:dbCAN_4 6.555799e-04 0.2002800
## GH:dbCAN_4:DIAMOND-CE:dbCAN_4 6.436096e-04 0.0576509
## GT:dbCAN_4:DIAMOND-CE:dbCAN_4 6.087203e-04 0.3809503
## PL:dbCAN_4:DIAMOND-CE:dbCAN_4 7.715049e-04 0.1565551
## CE:dbCAN_4:DIAMOND-CE:dbCAN_4 3.962275e-04 1.0000000
## AA:dbCAN_4:DIAMOND-CE:dbCAN_4 4.501102e-04 1.0000000
## CBM:dbCAN_4:DIAMOND-CE:dbCAN_4 6.487991e-04 0.2489785
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4 6.638759e-04 0.0244555
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4 5.895230e-04 0.5519088
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4 7.870687e-04 0.1036522
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4 4.234522e-04 1.0000000
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4 4.688114e-04 1.0000000
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4 5.964712e-04 0.6653015
## GH:CUPP-CE:dbCAN_4 6.718104e-04 0.0179748
## GT:CUPP-CE:dbCAN_4 6.526516e-04 0.1173644
## PL:CUPP-CE:dbCAN_4 7.976516e-04 0.0766820
## CE:CUPP-CE:dbCAN_4 4.544818e-04 1.0000000
## AA:CUPP-CE:dbCAN_4 5.133222e-04 1.0000000
## CBM:CUPP-CE:dbCAN_4 7.527250e-04 0.0059776
## CBM:dbCAN_4-AA:dbCAN_4 6.178579e-04 0.7148060
## GH:dbCAN_4:HMMER-AA:dbCAN_4 6.472075e-04 0.1565682
## GT:dbCAN_4:HMMER-AA:dbCAN_4 5.740140e-04 0.8811770
## PL:dbCAN_4:HMMER-AA:dbCAN_4 7.603515e-04 0.3520594
## CE:dbCAN_4:HMMER-AA:dbCAN_4 3.746066e-04 1.0000000
## AA:dbCAN_4:HMMER-AA:dbCAN_4 4.479038e-04 1.0000000
## CBM:dbCAN_4:HMMER-AA:dbCAN_4 6.310727e-04 0.6067069
## GH:dbCAN_4:DIAMOND-AA:dbCAN_4 6.203281e-04 0.3302304
## GT:dbCAN_4:DIAMOND-AA:dbCAN_4 5.847312e-04 0.8227836
## PL:dbCAN_4:DIAMOND-AA:dbCAN_4 7.448322e-04 0.4586552
## CE:dbCAN_4:DIAMOND-AA:dbCAN_4 3.686118e-04 1.0000000
## AA:dbCAN_4:DIAMOND-AA:dbCAN_4 4.222955e-04 1.0000000
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4 6.242579e-04 0.6738261
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4 6.406155e-04 0.1913162
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4 5.655340e-04 0.9222058
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4 7.603960e-04 0.3517716
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4 3.960213e-04 1.0000000
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4 4.409968e-04 1.0000000
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4 5.719640e-04 0.9560426
## GH:CUPP-AA:dbCAN_4 6.485289e-04 0.1550082
## GT:CUPP-AA:dbCAN_4 6.286422e-04 0.4707395
## PL:CUPP-AA:dbCAN_4 7.709789e-04 0.2868495
## CE:CUPP-AA:dbCAN_4 4.268661e-04 1.0000000
## AA:CUPP-AA:dbCAN_4 4.855076e-04 1.0000000
## CBM:CUPP-AA:dbCAN_4 7.281838e-04 0.0583983
## GH:dbCAN_4:HMMER-CBM:dbCAN_4 2.586143e-04 1.0000000
## GT:dbCAN_4:HMMER-CBM:dbCAN_4 1.939289e-04 1.0000000
## PL:dbCAN_4:HMMER-CBM:dbCAN_4 4.076626e-04 0.9999999
## CE:dbCAN_4:HMMER-CBM:dbCAN_4 2.867471e-05 0.1307370
## AA:dbCAN_4:HMMER-CBM:dbCAN_4 1.052794e-04 0.6494894
## CBM:dbCAN_4:HMMER-CBM:dbCAN_4 2.569631e-04 1.0000000
## GH:dbCAN_4:DIAMOND-CBM:dbCAN_4 2.320813e-04 1.0000000
## GT:dbCAN_4:DIAMOND-CBM:dbCAN_4 2.048718e-04 1.0000000
## PL:dbCAN_4:DIAMOND-CBM:dbCAN_4 3.921433e-04 1.0000000
## CE:dbCAN_4:DIAMOND-CBM:dbCAN_4 2.428170e-05 0.1121751
## AA:dbCAN_4:DIAMOND-CBM:dbCAN_4 7.967111e-05 0.4341010
## CBM:dbCAN_4:DIAMOND-CBM:dbCAN_4 2.505158e-04 1.0000000
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 2.521073e-04 1.0000000
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 1.856746e-04 1.0000000
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 4.077071e-04 0.9999999
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 5.008945e-05 0.2397030
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 9.837236e-05 0.5914568
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 1.978543e-04 1.0000000
## GH:CUPP-CBM:dbCAN_4 2.602822e-04 1.0000000
## GT:CUPP-CBM:dbCAN_4 2.490133e-04 1.0000000
## PL:CUPP-CBM:dbCAN_4 4.182901e-04 0.9999990
## CE:CUPP-CBM:dbCAN_4 8.253600e-05 0.4738055
## AA:CUPP-CBM:dbCAN_4 1.428832e-04 0.8994735
## CBM:CUPP-CBM:dbCAN_4 3.544416e-04 0.9984226
## GT:dbCAN_4:HMMER-GH:dbCAN_4:HMMER 9.616741e-05 0.9958417
## PL:dbCAN_4:HMMER-GH:dbCAN_4:HMMER 3.241018e-04 1.0000000
## CE:dbCAN_4:HMMER-GH:dbCAN_4:HMMER -5.217031e-05 0.0049217
## AA:dbCAN_4:HMMER-GH:dbCAN_4:HMMER 2.568807e-05 0.1217358
## CBM:dbCAN_4:HMMER-GH:dbCAN_4:HMMER 1.628883e-04 1.0000000
## GH:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 1.284556e-04 1.0000000
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 1.072579e-04 0.9995402
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 3.085825e-04 1.0000000
## CE:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER -5.595045e-05 0.0043755
## AA:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 7.976654e-08 0.0501487
## CBM:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 1.566542e-04 1.0000000
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 1.482742e-04 1.0000000
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 8.806063e-05 0.9838590
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 3.241463e-04 1.0000000
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER -3.075557e-05 0.0135722
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 1.878102e-05 0.0971337
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 1.037796e-04 0.9930089
## GH:CUPP-GH:dbCAN_4:HMMER 1.566564e-04 1.0000000
## GT:CUPP-GH:dbCAN_4:HMMER 1.515492e-04 1.0000000
## PL:CUPP-GH:dbCAN_4:HMMER 3.347292e-04 1.0000000
## CE:CUPP-GH:dbCAN_4:HMMER 2.303852e-06 0.0545771
## AA:CUPP-GH:dbCAN_4:HMMER 6.329183e-05 0.3432601
## CBM:CUPP-GH:dbCAN_4:HMMER 2.605800e-04 1.0000000
## PL:dbCAN_4:HMMER-GT:dbCAN_4:HMMER 4.273101e-04 0.9998391
## CE:dbCAN_4:HMMER-GT:dbCAN_4:HMMER 4.947550e-05 0.2466832
## AA:dbCAN_4:HMMER-GT:dbCAN_4:HMMER 1.266181e-04 0.8351498
## CBM:dbCAN_4:HMMER-GT:dbCAN_4:HMMER 2.723264e-04 1.0000000
## GH:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 2.438564e-04 0.9999972
## GT:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 2.188682e-04 1.0000000
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 4.117908e-04 0.9999900
## CE:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 4.534504e-05 0.2143174
## AA:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 1.010098e-04 0.6406701
## CBM:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 2.659627e-04 1.0000000
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 2.638082e-04 0.9989114
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 1.996710e-04 1.0000000
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 4.273546e-04 0.9998380
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 7.089024e-05 0.4106616
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 1.197111e-04 0.7891999
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 2.132176e-04 1.0000000
## GH:CUPP-GT:dbCAN_4:HMMER 2.720572e-04 0.9955812
## GT:CUPP-GT:dbCAN_4:HMMER 2.630667e-04 1.0000000
## PL:CUPP-GT:dbCAN_4:HMMER 4.379375e-04 0.9992425
## CE:CUPP-GT:dbCAN_4:HMMER 1.035993e-04 0.6847245
## AA:CUPP-GT:dbCAN_4:HMMER 1.642219e-04 0.9764055
## CBM:CUPP-GT:dbCAN_4:HMMER 3.698886e-04 0.8726911
## CE:dbCAN_4:HMMER-PL:dbCAN_4:HMMER -3.130886e-06 0.0453116
## AA:dbCAN_4:HMMER-PL:dbCAN_4:HMMER 7.130833e-05 0.3016412
## CBM:dbCAN_4:HMMER-PL:dbCAN_4:HMMER 2.444128e-04 1.0000000
## GH:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 2.297883e-04 1.0000000
## GT:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 1.964425e-04 0.9999734
## PL:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 3.648204e-04 1.0000000
## CE:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER -8.574887e-06 0.0382327
## AA:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 4.570002e-05 0.1725389
## CBM:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 2.377044e-04 1.0000000
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 2.500080e-04 1.0000000
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 1.772453e-04 0.9994185
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 3.803841e-04 1.0000000
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 1.828385e-05 0.0864666
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 6.440128e-05 0.2621537
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 1.853041e-04 0.9994810
## GH:CUPP-PL:dbCAN_4:HMMER 2.579892e-04 1.0000000
## GT:CUPP-PL:dbCAN_4:HMMER 2.404175e-04 1.0000000
## PL:CUPP-PL:dbCAN_4:HMMER 3.909671e-04 1.0000000
## CE:CUPP-PL:dbCAN_4:HMMER 4.967941e-05 0.1933871
## AA:CUPP-PL:dbCAN_4:HMMER 1.089121e-04 0.5613714
## CBM:CUPP-PL:dbCAN_4:HMMER 3.416303e-04 1.0000000
## AA:dbCAN_4:HMMER-CE:dbCAN_4:HMMER 5.036125e-04 1.0000000
## CBM:dbCAN_4:HMMER-CE:dbCAN_4:HMMER 6.834740e-04 0.0856579
## GH:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 6.715036e-04 0.0182198
## GT:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 6.366143e-04 0.1871674
## PL:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 7.993989e-04 0.0728451
## CE:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 4.241216e-04 1.0000000
## AA:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 4.780042e-04 1.0000000
## CBM:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 6.766932e-04 0.1120810
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 6.917700e-04 0.0068766
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 6.174171e-04 0.3117836
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 8.149627e-04 0.0452478
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 4.513463e-04 1.0000000
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 4.967055e-04 1.0000000
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 6.243653e-04 0.4207279
## GH:CUPP-CE:dbCAN_4:HMMER 6.997045e-04 0.0048821
## GT:CUPP-CE:dbCAN_4:HMMER 6.805456e-04 0.0438238
## PL:CUPP-CE:dbCAN_4:HMMER 8.255457e-04 0.0321234
## CE:CUPP-CE:dbCAN_4:HMMER 4.823759e-04 1.0000000
## AA:CUPP-CE:dbCAN_4:HMMER 5.412163e-04 1.0000000
## CBM:CUPP-CE:dbCAN_4:HMMER 7.806191e-04 0.0016188
## CBM:dbCAN_4:HMMER-AA:dbCAN_4:HMMER 6.391802e-04 0.5377454
## GH:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 6.284355e-04 0.2710242
## GT:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 5.928386e-04 0.7664527
## PL:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 7.529396e-04 0.4015474
## CE:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 3.767193e-04 1.0000000
## AA:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 4.304029e-04 1.0000000
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 6.323653e-04 0.6065469
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 6.487229e-04 0.1506497
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 5.736414e-04 0.8863367
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 7.685034e-04 0.3013764
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 4.041287e-04 1.0000000
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 4.491042e-04 1.0000000
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 5.800714e-04 0.9321214
## GH:CUPP-AA:dbCAN_4:HMMER 6.566364e-04 0.1204982
## GT:CUPP-AA:dbCAN_4:HMMER 6.367497e-04 0.4028949
## PL:CUPP-AA:dbCAN_4:HMMER 7.790863e-04 0.2422887
## CE:CUPP-AA:dbCAN_4:HMMER 4.349736e-04 1.0000000
## AA:CUPP-AA:dbCAN_4:HMMER 4.936150e-04 1.0000000
## CBM:CUPP-AA:dbCAN_4:HMMER 7.362912e-04 0.0441413
## GH:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 2.188665e-04 1.0000000
## GT:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 1.916570e-04 1.0000000
## PL:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 3.789285e-04 1.0000000
## CE:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 1.106689e-05 0.0732512
## AA:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 6.645630e-05 0.3323100
## CBM:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 2.373010e-04 1.0000000
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 2.388925e-04 1.0000000
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 1.724598e-04 1.0000000
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 3.944923e-04 1.0000000
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 3.687464e-05 0.1668735
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 8.515756e-05 0.4793676
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 1.846395e-04 1.0000000
## GH:CUPP-CBM:dbCAN_4:HMMER 2.470674e-04 1.0000000
## GT:CUPP-CBM:dbCAN_4:HMMER 2.357985e-04 1.0000000
## PL:CUPP-CBM:dbCAN_4:HMMER 4.050753e-04 1.0000000
## CE:CUPP-CBM:dbCAN_4:HMMER 6.932119e-05 0.3656400
## AA:CUPP-CBM:dbCAN_4:HMMER 1.296684e-04 0.8292435
## CBM:CUPP-CBM:dbCAN_4:HMMER 3.412268e-04 0.9998440
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND 1.356187e-04 1.0000000
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND 3.365922e-04 1.0000000
## CE:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND -2.801614e-05 0.0158819
## AA:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND 2.799981e-05 0.1308111
## CBM:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND 1.849151e-04 1.0000000
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 1.768137e-04 1.0000000
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 1.164214e-04 0.9999522
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 3.521560e-04 1.0000000
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND -2.807536e-06 0.0447548
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 4.670107e-05 0.2261072
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 1.320460e-04 0.9999790
## GH:CUPP-GH:dbCAN_4:DIAMOND 1.851897e-04 1.0000000
## GT:CUPP-GH:dbCAN_4:DIAMOND 1.799059e-04 1.0000000
## PL:CUPP-GH:dbCAN_4:DIAMOND 3.627390e-04 1.0000000
## CE:CUPP-GH:dbCAN_4:DIAMOND 3.023816e-05 0.1438774
## AA:CUPP-GH:dbCAN_4:DIAMOND 9.121188e-05 0.5865241
## CBM:CUPP-GH:dbCAN_4:DIAMOND 2.888409e-04 0.9997885
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4:DIAMOND 4.019378e-04 0.9999990
## CE:dbCAN_4:DIAMOND-GT:dbCAN_4:DIAMOND 3.543968e-05 0.1617082
## AA:dbCAN_4:DIAMOND-GT:dbCAN_4:DIAMOND 9.109434e-05 0.5532171
## CBM:dbCAN_4:DIAMOND-GT:dbCAN_4:DIAMOND 2.562697e-04 1.0000000
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 2.542649e-04 0.9999208
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 1.900351e-04 1.0000000
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 4.175016e-04 0.9999732
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 6.099454e-05 0.3287416
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 1.097956e-04 0.7129905
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 2.035279e-04 1.0000000
## GH:CUPP-GT:dbCAN_4:DIAMOND 2.625109e-04 0.9994951
## GT:CUPP-GT:dbCAN_4:DIAMOND 2.534285e-04 1.0000000
## PL:CUPP-GT:dbCAN_4:DIAMOND 4.280846e-04 0.9998358
## CE:CUPP-GT:dbCAN_4:DIAMOND 9.369398e-05 0.5967410
## AA:CUPP-GT:dbCAN_4:DIAMOND 1.543064e-04 0.9554032
## CBM:CUPP-GT:dbCAN_4:DIAMOND 3.601956e-04 0.9427680
## CE:dbCAN_4:DIAMOND-PL:dbCAN_4:DIAMOND 6.944421e-06 0.0616965
## AA:dbCAN_4:DIAMOND-PL:dbCAN_4:DIAMOND 6.121933e-05 0.2451017
## CBM:dbCAN_4:DIAMOND-PL:dbCAN_4:DIAMOND 2.532237e-04 1.0000000
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 2.655273e-04 1.0000000
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 1.927646e-04 0.9999484
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 3.959035e-04 1.0000000
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 3.380316e-05 0.1324648
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 7.992059e-05 0.3553336
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 2.008234e-04 0.9999503
## GH:CUPP-PL:dbCAN_4:DIAMOND 2.735085e-04 1.0000000
## GT:CUPP-PL:dbCAN_4:DIAMOND 2.559369e-04 1.0000000
## PL:CUPP-PL:dbCAN_4:DIAMOND 4.064864e-04 1.0000000
## CE:CUPP-PL:dbCAN_4:DIAMOND 6.519872e-05 0.2730115
## AA:CUPP-PL:dbCAN_4:DIAMOND 1.244314e-04 0.6746961
## CBM:CUPP-PL:dbCAN_4:DIAMOND 3.571496e-04 1.0000000
## AA:dbCAN_4:DIAMOND-CE:dbCAN_4:DIAMOND 4.961827e-04 1.0000000
## CBM:dbCAN_4:DIAMOND-CE:dbCAN_4:DIAMOND 6.964568e-04 0.0960066
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 7.121597e-04 0.0060791
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 6.374502e-04 0.2726503
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 8.336919e-04 0.0381786
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 4.697096e-04 1.0000000
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 5.148840e-04 1.0000000
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 6.441455e-04 0.3722883
## GH:CUPP-CE:dbCAN_4:DIAMOND 7.200839e-04 0.0043384
## GT:CUPP-CE:dbCAN_4:DIAMOND 7.005688e-04 0.0376033
## PL:CUPP-CE:dbCAN_4:DIAMOND 8.442749e-04 0.0270614
## CE:CUPP-CE:dbCAN_4:DIAMOND 5.006502e-04 1.0000000
## AA:CUPP-CE:dbCAN_4:DIAMOND 5.593948e-04 1.0000000
## CBM:CUPP-CE:dbCAN_4:DIAMOND 8.003827e-04 0.0014256
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND 6.579736e-04 0.3936078
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 6.743312e-04 0.0644007
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 5.992497e-04 0.7169713
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 7.941117e-04 0.1723562
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 4.297370e-04 1.0000000
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 4.747125e-04 1.0000000
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 6.056797e-04 0.8030321
## GH:CUPP-AA:dbCAN_4:DIAMOND 6.822447e-04 0.0496274
## GT:CUPP-AA:dbCAN_4:DIAMOND 6.623580e-04 0.2223973
## PL:CUPP-AA:dbCAN_4:DIAMOND 8.046946e-04 0.1328165
## CE:CUPP-AA:dbCAN_4:DIAMOND 4.605819e-04 1.0000000
## AA:CUPP-AA:dbCAN_4:DIAMOND 5.192233e-04 1.0000000
## CBM:CUPP-AA:dbCAN_4:DIAMOND 7.618995e-04 0.0170091
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 2.477625e-04 1.0000000
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 1.811984e-04 1.0000000
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 4.028894e-04 1.0000000
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 4.519930e-05 0.2100359
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 9.344818e-05 0.5479268
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 1.932977e-04 1.0000000
## GH:CUPP-CBM:dbCAN_4:DIAMOND 2.559332e-04 1.0000000
## GT:CUPP-CBM:dbCAN_4:DIAMOND 2.445338e-04 1.0000000
## PL:CUPP-CBM:dbCAN_4:DIAMOND 4.134723e-04 0.9999998
## CE:CUPP-CBM:dbCAN_4:DIAMOND 7.762926e-05 0.4310959
## AA:CUPP-CBM:dbCAN_4:DIAMOND 1.379590e-04 0.8744946
## CBM:CUPP-CBM:dbCAN_4:DIAMOND 3.498800e-04 0.9994189
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub 9.501543e-05 0.9944263
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub 3.310149e-04 1.0000000
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub -2.390210e-05 0.0184537
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub 2.562764e-05 0.1214638
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub 1.107111e-04 0.9976685
## GH:CUPP-GH:dbCAN_4:dbCAN-sub 1.636537e-04 1.0000000
## GT:CUPP-GH:dbCAN_4:dbCAN-sub 1.585030e-04 1.0000000
## PL:CUPP-GH:dbCAN_4:dbCAN-sub 3.415978e-04 1.0000000
## CE:CUPP-GH:dbCAN_4:dbCAN-sub 9.153960e-06 0.0703433
## AA:CUPP-GH:dbCAN_4:dbCAN-sub 7.013845e-05 0.3990095
## CBM:CUPP-GH:dbCAN_4:dbCAN-sub 2.675103e-04 0.9999995
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:dbCAN-sub 4.366989e-04 0.9994149
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4:dbCAN-sub 8.019178e-05 0.4924751
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4:dbCAN-sub 1.289928e-04 0.8486853
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4:dbCAN-sub 2.227251e-04 1.0000000
## GH:CUPP-GT:dbCAN_4:dbCAN-sub 2.817082e-04 0.9831659
## GT:CUPP-GT:dbCAN_4:dbCAN-sub 2.726258e-04 0.9999995
## PL:CUPP-GT:dbCAN_4:dbCAN-sub 4.472818e-04 0.9977553
## CE:CUPP-GT:dbCAN_4:dbCAN-sub 1.128912e-04 0.7592630
## AA:CUPP-GT:dbCAN_4:dbCAN-sub 1.735036e-04 0.9878021
## CBM:CUPP-GT:dbCAN_4:dbCAN-sub 3.793928e-04 0.7907169
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4:dbCAN-sub 1.823936e-05 0.0863564
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4:dbCAN-sub 6.435679e-05 0.2619103
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4:dbCAN-sub 1.852596e-04 0.9994779
## GH:CUPP-PL:dbCAN_4:dbCAN-sub 2.579447e-04 1.0000000
## GT:CUPP-PL:dbCAN_4:dbCAN-sub 2.403731e-04 1.0000000
## PL:CUPP-PL:dbCAN_4:dbCAN-sub 3.909226e-04 1.0000000
## CE:CUPP-PL:dbCAN_4:dbCAN-sub 4.963493e-05 0.1931851
## AA:CUPP-PL:dbCAN_4:dbCAN-sub 1.088676e-04 0.5610412
## CBM:CUPP-PL:dbCAN_4:dbCAN-sub 3.415858e-04 1.0000000
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4:dbCAN-sub 4.752908e-04 1.0000000
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4:dbCAN-sub 6.029506e-04 0.6088076
## GH:CUPP-CE:dbCAN_4:dbCAN-sub 6.782898e-04 0.0134493
## GT:CUPP-CE:dbCAN_4:dbCAN-sub 6.591309e-04 0.0947212
## PL:CUPP-CE:dbCAN_4:dbCAN-sub 8.041310e-04 0.0632524
## CE:CUPP-CE:dbCAN_4:dbCAN-sub 4.609612e-04 1.0000000
## AA:CUPP-CE:dbCAN_4:dbCAN-sub 5.198016e-04 1.0000000
## CBM:CUPP-CE:dbCAN_4:dbCAN-sub 7.592043e-04 0.0044574
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub 5.869785e-04 0.9055261
## GH:CUPP-AA:dbCAN_4:dbCAN-sub 6.635434e-04 0.0961344
## GT:CUPP-AA:dbCAN_4:dbCAN-sub 6.436567e-04 0.3484622
## PL:CUPP-AA:dbCAN_4:dbCAN-sub 7.859934e-04 0.2080880
## CE:CUPP-AA:dbCAN_4:dbCAN-sub 4.418806e-04 1.0000000
## AA:CUPP-AA:dbCAN_4:dbCAN-sub 5.005220e-04 1.0000000
## CBM:CUPP-AA:dbCAN_4:dbCAN-sub 7.431982e-04 0.0344798
## GH:CUPP-CBM:dbCAN_4:dbCAN-sub 3.061761e-04 0.9926130
## GT:CUPP-CBM:dbCAN_4:dbCAN-sub 2.949073e-04 0.9999997
## PL:CUPP-CBM:dbCAN_4:dbCAN-sub 4.641840e-04 0.9980592
## CE:CUPP-CBM:dbCAN_4:dbCAN-sub 1.284299e-04 0.8401337
## AA:CUPP-CBM:dbCAN_4:dbCAN-sub 1.887771e-04 0.9945301
## CBM:CUPP-CBM:dbCAN_4:dbCAN-sub 4.003356e-04 0.8516208
## GT:CUPP-GH:CUPP 1.517050e-04 1.0000000
## PL:CUPP-GH:CUPP 3.345381e-04 1.0000000
## CE:CUPP-GH:CUPP 2.037286e-06 0.0540231
## AA:CUPP-GH:CUPP 6.301100e-05 0.3402968
## CBM:CUPP-GH:CUPP 2.606400e-04 1.0000000
## PL:CUPP-GT:CUPP 3.850597e-04 1.0000000
## CE:CUPP-GT:CUPP 5.061547e-05 0.2457417
## AA:CUPP-GT:CUPP 1.112175e-04 0.7233278
## CBM:CUPP-GT:CUPP 3.173338e-04 0.9998933
## CE:CUPP-PL:CUPP 3.905198e-05 0.1493272
## AA:CUPP-PL:CUPP 9.828465e-05 0.4829314
## CBM:CUPP-PL:CUPP 3.310028e-04 1.0000000
## AA:CUPP-CE:CUPP 5.011405e-04 1.0000000
## CBM:CUPP-CE:CUPP 7.421284e-04 0.0185795
## CBM:CUPP-AA:CUPP 6.986874e-04 0.146606310.2.3 Sensitivity
| CAZy_class | Prediction_tool | Mean | Standard Deviation | Lower CI | Upper CI |
|---|---|---|---|---|---|
| GH | dbCAN_4 | 0.9197 | 0.2355 | 0.8799 | 0.9595 |
| GH | dbCAN_4:HMMER | 0.8868 | 0.2684 | 0.8418 | 0.9318 |
| GH | dbCAN_4:DIAMOND | 0.9489 | 0.1753 | 0.9191 | 0.9787 |
| GH | dbCAN_4:dbCAN-sub | 0.9096 | 0.2496 | 0.8676 | 0.9516 |
| GH | CUPP | 0.7845 | 0.3643 | 0.7225 | 0.8465 |
| GT | dbCAN_4 | 0.9103 | 0.2389 | 0.8557 | 0.9649 |
| GT | dbCAN_4:HMMER | 0.8644 | 0.2718 | 0.8027 | 0.9261 |
| GT | dbCAN_4:DIAMOND | 0.9360 | 0.1867 | 0.8933 | 0.9787 |
| GT | dbCAN_4:dbCAN-sub | 0.9105 | 0.2391 | 0.8558 | 0.9651 |
| GT | CUPP | 0.8039 | 0.2981 | 0.7354 | 0.8725 |
| PL | dbCAN_4 | 0.9232 | 0.2313 | 0.8232 | 1.0233 |
| PL | dbCAN_4:HMMER | 0.9232 | 0.2313 | 0.8232 | 1.0233 |
| PL | dbCAN_4:DIAMOND | 0.9776 | 0.1042 | 0.9325 | 1.0226 |
| PL | dbCAN_4:dbCAN-sub | 0.9239 | 0.2315 | 0.8238 | 1.0240 |
| PL | CUPP | 0.7051 | 0.4164 | 0.5251 | 0.8852 |
| CE | dbCAN_4 | 0.8773 | 0.3199 | 0.7182 | 1.0364 |
| CE | dbCAN_4:HMMER | 0.8670 | 0.3173 | 0.7091 | 1.0248 |
| CE | dbCAN_4:DIAMOND | 0.9706 | 0.0472 | 0.9463 | 0.9949 |
| CE | dbCAN_4:dbCAN-sub | 0.8787 | 0.3204 | 0.7193 | 1.0380 |
| CE | CUPP | 0.7414 | 0.4256 | 0.5226 | 0.9602 |
| AA | dbCAN_4 | 0.9102 | 0.2570 | 0.7732 | 1.0471 |
| AA | dbCAN_4:HMMER | 0.9085 | 0.2565 | 0.7718 | 1.0452 |
| AA | dbCAN_4:DIAMOND | 0.9567 | 0.1038 | 0.9014 | 1.0120 |
| AA | dbCAN_4:dbCAN-sub | 0.9093 | 0.2567 | 0.7725 | 1.0461 |
| AA | CUPP | 0.6941 | 0.4385 | 0.4604 | 0.9277 |
| CBM | dbCAN_4 | 0.8332 | 0.3345 | 0.7436 | 0.9228 |
| CBM | dbCAN_4:HMMER | 0.7311 | 0.3923 | 0.6261 | 0.8362 |
| CBM | dbCAN_4:DIAMOND | 0.8811 | 0.2943 | 0.8016 | 0.9607 |
| CBM | dbCAN_4:dbCAN-sub | 0.8012 | 0.3530 | 0.7066 | 0.8957 |
| CBM | CUPP | 0.0000 | 0.0000 | 0.0000 | 0.0000 |
Figure 10.5: 95% confidence intervals of the sensitivity of CAZy family classification across all CAZy families per CAZy class, for each CAZyme classifier.
Figure 10.6: Scatter plot of overlaying a one-dimensional box-and-whisker plot of sensitivity for each CAZy family for each CAZyme classifier. Each CAZy family is represented as a single point on the plot.
Test for significant differences between the means of the tools using a one-way ANOVA.
## Df Sum Sq Mean Sq F value Pr(>F)
## Prediction_tool 4 17.7 4.425 48.06 <2e-16 ***
## Residuals 1620 149.2 0.092
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1The means are statistically significantly different, therefore, use a post hoc Turkey HSD test to determine between which tools the means are significantly difference.
## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistical_parameter ~ Prediction_tool, data = fam_subset_sens_all)
##
## $Prediction_tool
## diff lwr upr
## dbCAN_4:HMMER-dbCAN_4 -0.042540009 -0.10729744 0.02221742
## dbCAN_4:DIAMOND-dbCAN_4 0.037766688 -0.02734013 0.10287350
## dbCAN_4:dbCAN-sub-dbCAN_4 -0.009575765 -0.07443168 0.05528015
## CUPP-dbCAN_4 -0.257936142 -0.32309396 -0.19277833
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.080306697 0.01534755 0.14526584
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.032964244 -0.03174343 0.09767192
## CUPP-dbCAN_4:HMMER -0.215396133 -0.28040639 -0.15038587
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND -0.047342453 -0.11239978 0.01771487
## CUPP-dbCAN_4:DIAMOND -0.295702830 -0.36106113 -0.23034453
## CUPP-dbCAN_4:dbCAN-sub -0.248360377 -0.31346874 -0.18325201
## p adj
## dbCAN_4:HMMER-dbCAN_4 0.3774033
## dbCAN_4:DIAMOND-dbCAN_4 0.5078260
## dbCAN_4:dbCAN-sub-dbCAN_4 0.9944412
## CUPP-dbCAN_4 0.0000000
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.0067416
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.6334382
## CUPP-dbCAN_4:HMMER 0.0000000
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND 0.2726191
## CUPP-dbCAN_4:DIAMOND 0.0000000
## CUPP-dbCAN_4:dbCAN-sub 0.0000000Now test for statistically significant differences between CAZy classes using a two-way ANOVA.
## Df Sum Sq Mean Sq F value Pr(>F)
## CAZy_class 5 12.84 2.568 34.37 <2e-16 ***
## Prediction_tool 4 17.70 4.424 59.21 <2e-16 ***
## CAZy_class:Prediction_tool 20 17.15 0.858 11.48 <2e-16 ***
## Residuals 1595 119.18 0.075
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1Statistically significant difference was detected so follow up with a Tukey test to determine if there are differences between specific groups.
## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistical_parameter ~ CAZy_class * Prediction_tool, data = fam_subset_sens_all)
##
## $`CAZy_class:Prediction_tool`
## diff lwr
## GT:dbCAN_4-GH:dbCAN_4 -9.424705e-03 -0.156255538
## PL:dbCAN_4-GH:dbCAN_4 3.501222e-03 -0.227827910
## CE:dbCAN_4-GH:dbCAN_4 -4.245425e-02 -0.299827759
## AA:dbCAN_4-GH:dbCAN_4 -9.570175e-03 -0.280789093
## CBM:dbCAN_4-GH:dbCAN_4 -8.651691e-02 -0.249341085
## GH:dbCAN_4:HMMER-GH:dbCAN_4 -3.296069e-02 -0.156550137
## GT:dbCAN_4:HMMER-GH:dbCAN_4 -5.534927e-02 -0.201565563
## PL:dbCAN_4:HMMER-GH:dbCAN_4 3.501222e-03 -0.227827910
## CE:dbCAN_4:HMMER-GH:dbCAN_4 -5.276791e-02 -0.310141422
## AA:dbCAN_4:HMMER-GH:dbCAN_4 -1.123684e-02 -0.282455760
## CBM:dbCAN_4:HMMER-GH:dbCAN_4 -1.885718e-01 -0.351396018
## GH:dbCAN_4:DIAMOND-GH:dbCAN_4 2.917832e-02 -0.095316660
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4 1.628205e-02 -0.130548778
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4 5.784905e-02 -0.173480084
## CE:dbCAN_4:DIAMOND-GH:dbCAN_4 5.085596e-02 -0.213123513
## AA:dbCAN_4:DIAMOND-GH:dbCAN_4 3.700969e-02 -0.234209232
## CBM:dbCAN_4:DIAMOND-GH:dbCAN_4 -3.858840e-02 -0.202459936
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4 -1.012709e-02 -0.133938614
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4 -9.252262e-03 -0.156083095
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4 4.191353e-03 -0.227137779
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4 -4.106536e-02 -0.298438870
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4 -1.040351e-02 -0.281622427
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4 -1.185528e-01 -0.281376934
## GH:CUPP-GH:dbCAN_4 -1.352020e-01 -0.259696955
## GT:CUPP-GH:dbCAN_4 -1.157843e-01 -0.263243421
## PL:CUPP-GH:dbCAN_4 -2.145802e-01 -0.445909346
## CE:CUPP-GH:dbCAN_4 -1.783071e-01 -0.442286539
## AA:CUPP-GH:dbCAN_4 -2.256261e-01 -0.496845057
## CBM:CUPP-GH:dbCAN_4 -9.197217e-01 -1.083593226
## PL:dbCAN_4-GT:dbCAN_4 1.292593e-02 -0.231384173
## CE:dbCAN_4-GT:dbCAN_4 -3.302954e-02 -0.302130605
## AA:dbCAN_4-GT:dbCAN_4 -1.454695e-04 -0.282517493
## CBM:dbCAN_4-GT:dbCAN_4 -7.709220e-02 -0.257884819
## GH:dbCAN_4:HMMER-GT:dbCAN_4 -2.353598e-02 -0.169989420
## GT:dbCAN_4:HMMER-GT:dbCAN_4 -4.592456e-02 -0.211916920
## PL:dbCAN_4:HMMER-GT:dbCAN_4 1.292593e-02 -0.231384173
## CE:dbCAN_4:HMMER-GT:dbCAN_4 -4.334320e-02 -0.312444268
## AA:dbCAN_4:HMMER-GT:dbCAN_4 -1.812136e-03 -0.284184159
## CBM:dbCAN_4:HMMER-GT:dbCAN_4 -1.791471e-01 -0.359939752
## GH:dbCAN_4:DIAMOND-GT:dbCAN_4 3.860302e-02 -0.108615377
## GT:dbCAN_4:DIAMOND-GT:dbCAN_4 2.570676e-02 -0.140827174
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4 6.727375e-02 -0.177036347
## CE:dbCAN_4:DIAMOND-GT:dbCAN_4 6.028066e-02 -0.215145223
## AA:dbCAN_4:DIAMOND-GT:dbCAN_4 4.643439e-02 -0.235937632
## CBM:dbCAN_4:DIAMOND-GT:dbCAN_4 -2.916369e-02 -0.210900147
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4 -7.023870e-04 -0.147343277
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4 1.724435e-04 -0.166361490
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4 1.361606e-02 -0.230694042
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4 -3.164065e-02 -0.300741716
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4 -9.788028e-04 -0.283350826
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4 -1.091280e-01 -0.289920668
## GH:CUPP-GT:dbCAN_4 -1.257773e-01 -0.272995672
## GT:CUPP-GT:dbCAN_4 -1.063596e-01 -0.273447749
## PL:CUPP-GT:dbCAN_4 -2.051555e-01 -0.449465608
## CE:CUPP-GT:dbCAN_4 -1.688824e-01 -0.444308249
## AA:CUPP-GT:dbCAN_4 -2.162014e-01 -0.498573457
## CBM:CUPP-GT:dbCAN_4 -9.102970e-01 -1.092033437
## CE:dbCAN_4-PL:dbCAN_4 -4.595547e-02 -0.369017780
## AA:dbCAN_4-PL:dbCAN_4 -1.307140e-02 -0.347268695
## CBM:dbCAN_4-PL:dbCAN_4 -9.001813e-02 -0.344261801
## GH:dbCAN_4:HMMER-PL:dbCAN_4 -3.646191e-02 -0.267551684
## GT:dbCAN_4:HMMER-PL:dbCAN_4 -5.885049e-02 -0.302791747
## PL:dbCAN_4:HMMER-PL:dbCAN_4 6.661338e-16 -0.302723140
## CE:dbCAN_4:HMMER-PL:dbCAN_4 -5.626913e-02 -0.379331442
## AA:dbCAN_4:HMMER-PL:dbCAN_4 -1.473806e-02 -0.348935361
## CBM:dbCAN_4:HMMER-PL:dbCAN_4 -1.920731e-01 -0.446316734
## GH:dbCAN_4:DIAMOND-PL:dbCAN_4 2.567709e-02 -0.205898231
## GT:dbCAN_4:DIAMOND-PL:dbCAN_4 1.278083e-02 -0.231529268
## PL:dbCAN_4:DIAMOND-PL:dbCAN_4 5.434783e-02 -0.248375314
## CE:dbCAN_4:DIAMOND-PL:dbCAN_4 4.735474e-02 -0.280994610
## AA:dbCAN_4:DIAMOND-PL:dbCAN_4 3.350846e-02 -0.300688833
## CBM:dbCAN_4:DIAMOND-PL:dbCAN_4 -4.208962e-02 -0.297005319
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4 -1.362831e-02 -0.244836932
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4 -1.275348e-02 -0.257063585
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4 6.901311e-04 -0.302033009
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4 -4.456658e-02 -0.367628891
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4 -1.390473e-02 -0.348102028
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4 -1.220540e-01 -0.376297650
## GH:CUPP-PL:dbCAN_4 -1.387032e-01 -0.370278526
## GT:CUPP-PL:dbCAN_4 -1.192856e-01 -0.363973753
## PL:CUPP-PL:dbCAN_4 -2.180814e-01 -0.520804575
## CE:CUPP-PL:dbCAN_4 -1.818083e-01 -0.510157636
## AA:CUPP-PL:dbCAN_4 -2.291274e-01 -0.563324659
## CBM:CUPP-PL:dbCAN_4 -9.232229e-01 -1.178138609
## AA:dbCAN_4-CE:dbCAN_4 3.288407e-02 -0.319842158
## CBM:dbCAN_4-CE:dbCAN_4 -4.406266e-02 -0.322213345
## GH:dbCAN_4:HMMER-CE:dbCAN_4 9.493558e-03 -0.247664841
## GT:dbCAN_4:HMMER-CE:dbCAN_4 -1.289502e-02 -0.281661268
## PL:dbCAN_4:HMMER-CE:dbCAN_4 4.595547e-02 -0.277106845
## CE:dbCAN_4:HMMER-CE:dbCAN_4 -1.031366e-02 -0.352508367
## AA:dbCAN_4:HMMER-CE:dbCAN_4 3.121740e-02 -0.321508824
## CBM:dbCAN_4:HMMER-CE:dbCAN_4 -1.461176e-01 -0.424268279
## GH:dbCAN_4:DIAMOND-CE:dbCAN_4 7.163256e-02 -0.185962255
## GT:dbCAN_4:DIAMOND-CE:dbCAN_4 5.873630e-02 -0.210364766
## PL:dbCAN_4:DIAMOND-CE:dbCAN_4 1.003033e-01 -0.222759019
## CE:dbCAN_4:DIAMOND-CE:dbCAN_4 9.331020e-02 -0.253880308
## AA:dbCAN_4:DIAMOND-CE:dbCAN_4 7.946393e-02 -0.273262297
## CBM:dbCAN_4:DIAMOND-CE:dbCAN_4 3.865845e-03 -0.274899236
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4 3.232715e-02 -0.224938047
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4 3.320198e-02 -0.235899082
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4 4.664560e-02 -0.276416714
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4 1.388889e-03 -0.340805816
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4 3.205074e-02 -0.320675491
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4 -7.609851e-02 -0.354249194
## GH:CUPP-CE:dbCAN_4 -9.274773e-02 -0.350342550
## GT:CUPP-CE:dbCAN_4 -7.333008e-02 -0.342774464
## PL:CUPP-CE:dbCAN_4 -1.721260e-01 -0.495188280
## CE:CUPP-CE:dbCAN_4 -1.358528e-01 -0.483043334
## AA:CUPP-CE:dbCAN_4 -1.831719e-01 -0.535898122
## CBM:CUPP-CE:dbCAN_4 -8.772674e-01 -1.156032526
## CBM:dbCAN_4-AA:dbCAN_4 -7.694673e-02 -0.367955974
## GH:dbCAN_4:HMMER-AA:dbCAN_4 -2.339051e-02 -0.294405305
## GT:dbCAN_4:HMMER-AA:dbCAN_4 -4.577909e-02 -0.327832050
## PL:dbCAN_4:HMMER-AA:dbCAN_4 1.307140e-02 -0.321125900
## CE:dbCAN_4:HMMER-AA:dbCAN_4 -4.319773e-02 -0.395923961
## AA:dbCAN_4:HMMER-AA:dbCAN_4 -1.666667e-03 -0.364618961
## CBM:dbCAN_4:HMMER-AA:dbCAN_4 -1.790017e-01 -0.470010907
## GH:dbCAN_4:DIAMOND-AA:dbCAN_4 3.874849e-02 -0.232680441
## GT:dbCAN_4:DIAMOND-AA:dbCAN_4 2.585223e-02 -0.256519794
## PL:dbCAN_4:DIAMOND-AA:dbCAN_4 6.741922e-02 -0.266778074
## CE:dbCAN_4:DIAMOND-AA:dbCAN_4 6.042613e-02 -0.297148792
## AA:dbCAN_4:DIAMOND-AA:dbCAN_4 4.657986e-02 -0.316372433
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4 -2.901823e-02 -0.320614773
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4 -5.569175e-04 -0.271673053
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4 3.179130e-04 -0.282054110
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4 1.376153e-02 -0.320435769
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4 -3.149518e-02 -0.384221409
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4 -8.333333e-04 -0.363785627
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4 -1.089826e-01 -0.399991823
## GH:CUPP-AA:dbCAN_4 -1.256318e-01 -0.397060736
## GT:CUPP-AA:dbCAN_4 -1.062142e-01 -0.388913376
## PL:CUPP-AA:dbCAN_4 -2.050100e-01 -0.539207336
## CE:CUPP-AA:dbCAN_4 -1.687369e-01 -0.526311818
## AA:CUPP-AA:dbCAN_4 -2.160560e-01 -0.579008258
## CBM:CUPP-AA:dbCAN_4 -9.101515e-01 -1.201748063
## GH:dbCAN_4:HMMER-CBM:dbCAN_4 5.355622e-02 -0.108927718
## GT:dbCAN_4:HMMER-CBM:dbCAN_4 3.116764e-02 -0.149126240
## PL:dbCAN_4:HMMER-CBM:dbCAN_4 9.001813e-02 -0.164225544
## CE:dbCAN_4:HMMER-CBM:dbCAN_4 3.374900e-02 -0.244401687
## AA:dbCAN_4:HMMER-CBM:dbCAN_4 7.528006e-02 -0.215729178
## CBM:dbCAN_4:HMMER-CBM:dbCAN_4 -1.020549e-01 -0.296061095
## GH:dbCAN_4:DIAMOND-CBM:dbCAN_4 1.156952e-01 -0.047478540
## GT:dbCAN_4:DIAMOND-CBM:dbCAN_4 1.027990e-01 -0.077993658
## PL:dbCAN_4:DIAMOND-CBM:dbCAN_4 1.443660e-01 -0.109877718
## CE:dbCAN_4:DIAMOND-CBM:dbCAN_4 1.373729e-01 -0.146901368
## AA:dbCAN_4:DIAMOND-CBM:dbCAN_4 1.235266e-01 -0.167482651
## CBM:dbCAN_4:DIAMOND-CBM:dbCAN_4 4.792851e-02 -0.146957507
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 7.638981e-02 -0.086263100
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 7.726464e-02 -0.103527975
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 9.070826e-02 -0.163535413
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 4.545155e-02 -0.232699135
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 7.611340e-02 -0.214895845
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 -3.203585e-02 -0.226042011
## GH:CUPP-CBM:dbCAN_4 -4.868507e-02 -0.211858835
## GT:CUPP-CBM:dbCAN_4 -2.926742e-02 -0.210570654
## PL:CUPP-CBM:dbCAN_4 -1.280633e-01 -0.382306980
## CE:CUPP-CBM:dbCAN_4 -9.179016e-02 -0.376064394
## AA:CUPP-CBM:dbCAN_4 -1.391092e-01 -0.430118476
## CBM:CUPP-CBM:dbCAN_4 -8.332048e-01 -1.028090797
## GT:dbCAN_4:HMMER-GH:dbCAN_4:HMMER -2.238858e-02 -0.168225892
## PL:dbCAN_4:HMMER-GH:dbCAN_4:HMMER 3.646191e-02 -0.194627865
## CE:dbCAN_4:HMMER-GH:dbCAN_4:HMMER -1.980722e-02 -0.276965619
## AA:dbCAN_4:HMMER-GH:dbCAN_4:HMMER 2.172385e-02 -0.249290947
## CBM:dbCAN_4:HMMER-GH:dbCAN_4:HMMER -1.556112e-01 -0.318095088
## GH:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 6.213900e-02 -0.061910645
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 4.924274e-02 -0.097210697
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 9.080974e-02 -0.140280039
## CE:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 8.381665e-02 -0.179953098
## AA:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 6.997037e-02 -0.201044419
## CBM:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER -5.627713e-03 -0.169161186
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 2.283359e-02 -0.100530132
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 2.370843e-02 -0.122745013
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 3.715204e-02 -0.193937734
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER -8.104669e-03 -0.265263068
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 2.255718e-02 -0.248457614
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER -8.559207e-02 -0.248076004
## GH:CUPP-GH:dbCAN_4:HMMER -1.022413e-01 -0.226290940
## GT:CUPP-GH:dbCAN_4:HMMER -8.282364e-02 -0.229906952
## PL:CUPP-GH:dbCAN_4:HMMER -1.816195e-01 -0.412709300
## CE:CUPP-GH:dbCAN_4:HMMER -1.453464e-01 -0.409116124
## AA:CUPP-GH:dbCAN_4:HMMER -1.926655e-01 -0.463680245
## CBM:CUPP-GH:dbCAN_4:HMMER -8.867610e-01 -1.050294475
## PL:dbCAN_4:HMMER-GT:dbCAN_4:HMMER 5.885049e-02 -0.185090769
## CE:dbCAN_4:HMMER-GT:dbCAN_4:HMMER 2.581359e-03 -0.266184888
## AA:dbCAN_4:HMMER-GT:dbCAN_4:HMMER 4.411242e-02 -0.237940534
## CBM:dbCAN_4:HMMER-GT:dbCAN_4:HMMER -1.332226e-01 -0.313516452
## GH:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 8.452758e-02 -0.062077904
## GT:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 7.163132e-02 -0.094361038
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 1.131983e-01 -0.130742943
## CE:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 1.062052e-01 -0.168893541
## AA:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 9.235895e-02 -0.189694006
## CBM:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 1.676087e-02 -0.164479444
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 4.522217e-02 -0.100803380
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 4.609700e-02 -0.119895354
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 5.954062e-02 -0.184400638
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 1.428391e-02 -0.254482337
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 4.494576e-02 -0.237107200
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER -6.320349e-02 -0.243497368
## GH:CUPP-GT:dbCAN_4:HMMER -7.985271e-02 -0.226458200
## GT:CUPP-GT:dbCAN_4:HMMER -6.043506e-02 -0.226983415
## PL:CUPP-GT:dbCAN_4:HMMER -1.592309e-01 -0.403172204
## CE:CUPP-GT:dbCAN_4:HMMER -1.229578e-01 -0.398056567
## AA:CUPP-GT:dbCAN_4:HMMER -1.702769e-01 -0.452329831
## CBM:CUPP-GT:dbCAN_4:HMMER -8.643724e-01 -1.045612734
## CE:dbCAN_4:HMMER-PL:dbCAN_4:HMMER -5.626913e-02 -0.379331442
## AA:dbCAN_4:HMMER-PL:dbCAN_4:HMMER -1.473806e-02 -0.348935361
## CBM:dbCAN_4:HMMER-PL:dbCAN_4:HMMER -1.920731e-01 -0.446316734
## GH:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 2.567709e-02 -0.205898231
## GT:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 1.278083e-02 -0.231529268
## PL:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 5.434783e-02 -0.248375314
## CE:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 4.735474e-02 -0.280994610
## AA:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 3.350846e-02 -0.300688833
## CBM:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER -4.208962e-02 -0.297005319
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER -1.362831e-02 -0.244836932
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER -1.275348e-02 -0.257063585
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 6.901311e-04 -0.302033009
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER -4.456658e-02 -0.367628891
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER -1.390473e-02 -0.348102028
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER -1.220540e-01 -0.376297650
## GH:CUPP-PL:dbCAN_4:HMMER -1.387032e-01 -0.370278526
## GT:CUPP-PL:dbCAN_4:HMMER -1.192856e-01 -0.363973753
## PL:CUPP-PL:dbCAN_4:HMMER -2.180814e-01 -0.520804575
## CE:CUPP-PL:dbCAN_4:HMMER -1.818083e-01 -0.510157636
## AA:CUPP-PL:dbCAN_4:HMMER -2.291274e-01 -0.563324659
## CBM:CUPP-PL:dbCAN_4:HMMER -9.232229e-01 -1.178138609
## AA:dbCAN_4:HMMER-CE:dbCAN_4:HMMER 4.153107e-02 -0.311195161
## CBM:dbCAN_4:HMMER-CE:dbCAN_4:HMMER -1.358039e-01 -0.413954616
## GH:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 8.194622e-02 -0.175648592
## GT:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 6.904996e-02 -0.200051103
## PL:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 1.106170e-01 -0.212445356
## CE:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 1.036239e-01 -0.243566645
## AA:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 8.977759e-02 -0.262948634
## CBM:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 1.417951e-02 -0.264585573
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 4.264082e-02 -0.214624384
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 4.351565e-02 -0.225585419
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 5.695926e-02 -0.266103051
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 1.170255e-02 -0.330492153
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 4.236440e-02 -0.310361828
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER -6.578485e-02 -0.343935531
## GH:CUPP-CE:dbCAN_4:HMMER -8.243407e-02 -0.340028887
## GT:CUPP-CE:dbCAN_4:HMMER -6.301642e-02 -0.332460801
## PL:CUPP-CE:dbCAN_4:HMMER -1.618123e-01 -0.484874617
## CE:CUPP-CE:dbCAN_4:HMMER -1.255392e-01 -0.472729671
## AA:CUPP-CE:dbCAN_4:HMMER -1.728582e-01 -0.525584459
## CBM:CUPP-CE:dbCAN_4:HMMER -8.669538e-01 -1.145718863
## CBM:dbCAN_4:HMMER-AA:dbCAN_4:HMMER -1.773350e-01 -0.468344240
## GH:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 4.041516e-02 -0.231013775
## GT:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 2.751890e-02 -0.254853127
## PL:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 6.908589e-02 -0.265111407
## CE:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 6.209280e-02 -0.295482125
## AA:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 4.824653e-02 -0.314705766
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER -2.735156e-02 -0.318948106
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 1.109749e-03 -0.270006386
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 1.984580e-03 -0.280387443
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 1.542819e-02 -0.318769102
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER -2.982851e-02 -0.382554742
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 8.333333e-04 -0.362118961
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER -1.073159e-01 -0.398325156
## GH:CUPP-AA:dbCAN_4:HMMER -1.239651e-01 -0.395394070
## GT:CUPP-AA:dbCAN_4:HMMER -1.045475e-01 -0.387246709
## PL:CUPP-AA:dbCAN_4:HMMER -2.033434e-01 -0.537540669
## CE:CUPP-AA:dbCAN_4:HMMER -1.670702e-01 -0.524645152
## AA:CUPP-AA:dbCAN_4:HMMER -2.143893e-01 -0.577341591
## CBM:CUPP-AA:dbCAN_4:HMMER -9.084848e-01 -1.200081396
## GH:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 2.177502e-01 0.054576393
## GT:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 2.048539e-01 0.024061275
## PL:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 2.464209e-01 -0.007822785
## CE:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 2.394278e-01 -0.044846434
## AA:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 2.255815e-01 -0.065427717
## CBM:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 1.499834e-01 -0.044902574
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 1.784447e-01 0.015791833
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 1.793196e-01 -0.001473042
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 1.927632e-01 -0.061480480
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 1.475065e-01 -0.130644202
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 1.781683e-01 -0.112840912
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 7.001908e-02 -0.123987078
## GH:CUPP-CBM:dbCAN_4:HMMER 5.336986e-02 -0.109803902
## GT:CUPP-CBM:dbCAN_4:HMMER 7.278751e-02 -0.108515721
## PL:CUPP-CBM:dbCAN_4:HMMER -2.600837e-02 -0.280252047
## CE:CUPP-CBM:dbCAN_4:HMMER 1.026477e-02 -0.274009461
## AA:CUPP-CBM:dbCAN_4:HMMER -3.705430e-02 -0.328063543
## CBM:CUPP-CBM:dbCAN_4:HMMER -7.311499e-01 -0.926035864
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND -1.289626e-02 -0.160114659
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND 2.867073e-02 -0.202904591
## CE:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND 2.167764e-02 -0.242517597
## AA:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND 7.831371e-03 -0.263597561
## CBM:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND -6.776672e-02 -0.231985605
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND -3.930541e-02 -0.163576306
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND -3.843058e-02 -0.185648975
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND -2.498696e-02 -0.256562286
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND -7.024367e-02 -0.327838487
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND -3.958182e-02 -0.311010755
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND -1.477311e-01 -0.310904832
## GH:CUPP-GH:dbCAN_4:DIAMOND -1.643803e-01 -0.289332134
## GT:CUPP-GH:dbCAN_4:DIAMOND -1.449626e-01 -0.292807655
## PL:CUPP-GH:dbCAN_4:DIAMOND -2.437585e-01 -0.475333853
## CE:CUPP-GH:dbCAN_4:DIAMOND -2.074854e-01 -0.471680623
## AA:CUPP-GH:dbCAN_4:DIAMOND -2.548045e-01 -0.526233386
## CBM:CUPP-GH:dbCAN_4:DIAMOND -9.489000e-01 -1.113118895
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4:DIAMOND 4.156699e-02 -0.202743107
## CE:dbCAN_4:DIAMOND-GT:dbCAN_4:DIAMOND 3.457390e-02 -0.240851983
## AA:dbCAN_4:DIAMOND-GT:dbCAN_4:DIAMOND 2.072763e-02 -0.261644391
## CBM:dbCAN_4:DIAMOND-GT:dbCAN_4:DIAMOND -5.487045e-02 -0.236606907
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND -2.640915e-02 -0.173050036
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND -2.553432e-02 -0.192068250
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND -1.209070e-02 -0.256400801
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND -5.734741e-02 -0.326448476
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND -2.668556e-02 -0.309057586
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND -1.348348e-01 -0.315627428
## GH:CUPP-GT:dbCAN_4:DIAMOND -1.514840e-01 -0.298702432
## GT:CUPP-GT:dbCAN_4:DIAMOND -1.320664e-01 -0.299154509
## PL:CUPP-GT:dbCAN_4:DIAMOND -2.308623e-01 -0.475172368
## CE:CUPP-GT:dbCAN_4:DIAMOND -1.945891e-01 -0.470015009
## AA:CUPP-GT:dbCAN_4:DIAMOND -2.419082e-01 -0.524280216
## CBM:CUPP-GT:dbCAN_4:DIAMOND -9.360037e-01 -1.117740197
## CE:dbCAN_4:DIAMOND-PL:dbCAN_4:DIAMOND -6.993090e-03 -0.335342436
## AA:dbCAN_4:DIAMOND-PL:dbCAN_4:DIAMOND -2.083936e-02 -0.355036660
## CBM:dbCAN_4:DIAMOND-PL:dbCAN_4:DIAMOND -9.643745e-02 -0.351353145
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -6.797614e-02 -0.299184758
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -6.710131e-02 -0.311411411
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -5.365769e-02 -0.356380835
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -9.891440e-02 -0.421976717
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -6.825256e-02 -0.402449854
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -1.764018e-01 -0.430645476
## GH:CUPP-PL:dbCAN_4:DIAMOND -1.930510e-01 -0.424626352
## GT:CUPP-PL:dbCAN_4:DIAMOND -1.736334e-01 -0.418321579
## PL:CUPP-PL:dbCAN_4:DIAMOND -2.724293e-01 -0.575152401
## CE:CUPP-PL:dbCAN_4:DIAMOND -2.361561e-01 -0.564505462
## AA:CUPP-PL:dbCAN_4:DIAMOND -2.834752e-01 -0.617672485
## CBM:CUPP-PL:dbCAN_4:DIAMOND -9.775707e-01 -1.232486435
## AA:dbCAN_4:DIAMOND-CE:dbCAN_4:DIAMOND -1.384627e-02 -0.371421198
## CBM:dbCAN_4:DIAMOND-CE:dbCAN_4:DIAMOND -8.944436e-02 -0.374319781
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND -6.098305e-02 -0.324856920
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND -6.010822e-02 -0.335534108
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND -4.666461e-02 -0.375013952
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND -9.192131e-02 -0.439111827
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND -6.125947e-02 -0.418834393
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND -1.694087e-01 -0.453682946
## GH:CUPP-CE:dbCAN_4:DIAMOND -1.860579e-01 -0.450253178
## GT:CUPP-CE:dbCAN_4:DIAMOND -1.666403e-01 -0.442401615
## PL:CUPP-CE:dbCAN_4:DIAMOND -2.654362e-01 -0.593785518
## CE:CUPP-CE:dbCAN_4:DIAMOND -2.291630e-01 -0.581278472
## AA:CUPP-CE:dbCAN_4:DIAMOND -2.764821e-01 -0.634057024
## CBM:CUPP-CE:dbCAN_4:DIAMOND -9.705776e-01 -1.255453071
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND -7.559809e-02 -0.367194634
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND -4.713678e-02 -0.318252914
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND -4.626195e-02 -0.328633971
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND -3.281833e-02 -0.367015630
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND -7.807504e-02 -0.430801270
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND -4.741319e-02 -0.410365489
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND -1.555624e-01 -0.446571684
## GH:CUPP-AA:dbCAN_4:DIAMOND -1.722117e-01 -0.443640598
## GT:CUPP-AA:dbCAN_4:DIAMOND -1.527940e-01 -0.435493237
## PL:CUPP-AA:dbCAN_4:DIAMOND -2.515899e-01 -0.585787197
## CE:CUPP-AA:dbCAN_4:DIAMOND -2.153168e-01 -0.572891680
## AA:CUPP-AA:dbCAN_4:DIAMOND -2.626358e-01 -0.625588119
## CBM:CUPP-AA:dbCAN_4:DIAMOND -9.567314e-01 -1.248327924
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 2.846131e-02 -0.135240059
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 2.933614e-02 -0.152400314
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 4.277975e-02 -0.212135943
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND -2.476956e-03 -0.281242037
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 2.818489e-02 -0.263411656
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND -7.996435e-02 -0.274850368
## GH:CUPP-CBM:dbCAN_4:DIAMOND -9.661358e-02 -0.260832469
## GT:CUPP-CBM:dbCAN_4:DIAMOND -7.719593e-02 -0.259440349
## PL:CUPP-CBM:dbCAN_4:DIAMOND -1.759918e-01 -0.430907509
## CE:CUPP-CBM:dbCAN_4:DIAMOND -1.397187e-01 -0.424594090
## AA:CUPP-CBM:dbCAN_4:DIAMOND -1.870377e-01 -0.478634286
## CBM:CUPP-CBM:dbCAN_4:DIAMOND -8.811333e-01 -1.076895199
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub 8.748305e-04 -0.145766059
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub 1.431845e-02 -0.216890171
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub -3.093826e-02 -0.288203463
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub -2.764158e-04 -0.271392551
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub -1.084257e-01 -0.271078576
## GH:CUPP-GH:dbCAN_4:dbCAN-sub -1.250749e-01 -0.249345785
## GT:CUPP-GH:dbCAN_4:dbCAN-sub -1.056572e-01 -0.252927196
## PL:CUPP-GH:dbCAN_4:dbCAN-sub -2.044531e-01 -0.435661738
## CE:CUPP-GH:dbCAN_4:dbCAN-sub -1.681800e-01 -0.432053844
## AA:CUPP-GH:dbCAN_4:dbCAN-sub -2.154990e-01 -0.486615182
## CBM:CUPP-GH:dbCAN_4:dbCAN-sub -9.095946e-01 -1.073295965
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:dbCAN-sub 1.344362e-02 -0.230866485
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4:dbCAN-sub -3.181309e-02 -0.300914160
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4:dbCAN-sub -1.151246e-03 -0.283523269
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4:dbCAN-sub -1.093005e-01 -0.290093112
## GH:CUPP-GT:dbCAN_4:dbCAN-sub -1.259497e-01 -0.273168115
## GT:CUPP-GT:dbCAN_4:dbCAN-sub -1.065321e-01 -0.273620192
## PL:CUPP-GT:dbCAN_4:dbCAN-sub -2.053280e-01 -0.449638052
## CE:CUPP-GT:dbCAN_4:dbCAN-sub -1.690548e-01 -0.444480693
## AA:CUPP-GT:dbCAN_4:dbCAN-sub -2.163739e-01 -0.498745900
## CBM:CUPP-GT:dbCAN_4:dbCAN-sub -9.104694e-01 -1.092205881
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4:dbCAN-sub -4.525671e-02 -0.368319022
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4:dbCAN-sub -1.459486e-02 -0.348792159
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4:dbCAN-sub -1.227441e-01 -0.376987781
## GH:CUPP-PL:dbCAN_4:dbCAN-sub -1.393933e-01 -0.370968657
## GT:CUPP-PL:dbCAN_4:dbCAN-sub -1.199757e-01 -0.364663884
## PL:CUPP-PL:dbCAN_4:dbCAN-sub -2.187716e-01 -0.521494706
## CE:CUPP-PL:dbCAN_4:dbCAN-sub -1.824984e-01 -0.510847767
## AA:CUPP-PL:dbCAN_4:dbCAN-sub -2.298175e-01 -0.564014790
## CBM:CUPP-PL:dbCAN_4:dbCAN-sub -9.239130e-01 -1.178828740
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4:dbCAN-sub 3.066185e-02 -0.322064380
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4:dbCAN-sub -7.748740e-02 -0.355638083
## GH:CUPP-CE:dbCAN_4:dbCAN-sub -9.413662e-02 -0.351731439
## GT:CUPP-CE:dbCAN_4:dbCAN-sub -7.471897e-02 -0.344163353
## PL:CUPP-CE:dbCAN_4:dbCAN-sub -1.735149e-01 -0.496577169
## CE:CUPP-CE:dbCAN_4:dbCAN-sub -1.372417e-01 -0.484432223
## AA:CUPP-CE:dbCAN_4:dbCAN-sub -1.845608e-01 -0.537287011
## CBM:CUPP-CE:dbCAN_4:dbCAN-sub -8.786563e-01 -1.157421415
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub -1.081492e-01 -0.399158489
## GH:CUPP-AA:dbCAN_4:dbCAN-sub -1.247985e-01 -0.396227403
## GT:CUPP-AA:dbCAN_4:dbCAN-sub -1.053808e-01 -0.388080043
## PL:CUPP-AA:dbCAN_4:dbCAN-sub -2.041767e-01 -0.538374002
## CE:CUPP-AA:dbCAN_4:dbCAN-sub -1.679036e-01 -0.525478485
## AA:CUPP-AA:dbCAN_4:dbCAN-sub -2.152226e-01 -0.578174925
## CBM:CUPP-AA:dbCAN_4:dbCAN-sub -9.093182e-01 -1.200914729
## GH:CUPP-CBM:dbCAN_4:dbCAN-sub -1.664922e-02 -0.179822986
## GT:CUPP-CBM:dbCAN_4:dbCAN-sub 2.768425e-03 -0.178534805
## PL:CUPP-CBM:dbCAN_4:dbCAN-sub -9.602746e-02 -0.350271131
## CE:CUPP-CBM:dbCAN_4:dbCAN-sub -5.975431e-02 -0.344028545
## AA:CUPP-CBM:dbCAN_4:dbCAN-sub -1.070734e-01 -0.398082627
## CBM:CUPP-CBM:dbCAN_4:dbCAN-sub -8.011689e-01 -0.996054948
## GT:CUPP-GH:CUPP 1.941765e-02 -0.128427360
## PL:CUPP-GH:CUPP -7.937823e-02 -0.310953558
## CE:CUPP-GH:CUPP -4.310509e-02 -0.307300328
## AA:CUPP-GH:CUPP -9.042416e-02 -0.361853091
## CBM:CUPP-GH:CUPP -7.845197e-01 -0.948738600
## PL:CUPP-GT:CUPP -9.879588e-02 -0.343484084
## CE:CUPP-GT:CUPP -6.252274e-02 -0.338284065
## AA:CUPP-GT:CUPP -1.098418e-01 -0.392541031
## CBM:CUPP-GT:CUPP -8.039374e-01 -0.986181780
## CE:CUPP-PL:CUPP 3.627315e-02 -0.292076201
## AA:CUPP-PL:CUPP -1.104593e-02 -0.345243223
## CBM:CUPP-PL:CUPP -7.051415e-01 -0.960057173
## AA:CUPP-CE:CUPP -4.731907e-02 -0.404893997
## CBM:CUPP-CE:CUPP -7.414146e-01 -1.026290045
## CBM:CUPP-AA:CUPP -6.940956e-01 -0.985692099
## upr p adj
## GT:dbCAN_4-GH:dbCAN_4 0.1374061271 1.0000000
## PL:dbCAN_4-GH:dbCAN_4 0.2348303546 1.0000000
## CE:dbCAN_4-GH:dbCAN_4 0.2149192690 1.0000000
## AA:dbCAN_4-GH:dbCAN_4 0.2616487435 1.0000000
## CBM:dbCAN_4-GH:dbCAN_4 0.0763072729 0.9792316
## GH:dbCAN_4:HMMER-GH:dbCAN_4 0.0906287618 1.0000000
## GT:dbCAN_4:HMMER-GH:dbCAN_4 0.0908670301 0.9999269
## PL:dbCAN_4:HMMER-GH:dbCAN_4 0.2348303546 1.0000000
## CE:dbCAN_4:HMMER-GH:dbCAN_4 0.2046056060 1.0000000
## AA:dbCAN_4:HMMER-GH:dbCAN_4 0.2599820768 1.0000000
## CBM:dbCAN_4:HMMER-GH:dbCAN_4 -0.0257476602 0.0051900
## GH:dbCAN_4:DIAMOND-GH:dbCAN_4 0.1536732908 1.0000000
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4 0.1631128868 1.0000000
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4 0.2891781807 1.0000000
## CE:dbCAN_4:DIAMOND-GH:dbCAN_4 0.3148354304 1.0000000
## AA:dbCAN_4:DIAMOND-GH:dbCAN_4 0.3082286046 1.0000000
## CBM:dbCAN_4:DIAMOND-GH:dbCAN_4 0.1252831362 1.0000000
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4 0.1136844287 1.0000000
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4 0.1375785706 1.0000000
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4 0.2355204857 1.0000000
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4 0.2163081578 1.0000000
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4 0.2608154101 1.0000000
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4 0.0442714240 0.6002718
## GH:CUPP-GH:dbCAN_4 -0.0107070045 0.0155181
## GT:CUPP-GH:dbCAN_4 0.0316747621 0.4249226
## PL:CUPP-GH:dbCAN_4 0.0167489191 0.1177647
## CE:CUPP-GH:dbCAN_4 0.0856724041 0.7547391
## AA:CUPP-GH:dbCAN_4 0.0455927794 0.2973441
## CBM:CUPP-GH:dbCAN_4 -0.7558501538 0.0000000
## PL:dbCAN_4-GT:dbCAN_4 0.2572360283 1.0000000
## CE:dbCAN_4-GT:dbCAN_4 0.2360715259 1.0000000
## AA:dbCAN_4-GT:dbCAN_4 0.2822265537 1.0000000
## CBM:dbCAN_4-GT:dbCAN_4 0.1037004182 0.9993164
## GH:dbCAN_4:HMMER-GT:dbCAN_4 0.1229174567 1.0000000
## GT:dbCAN_4:HMMER-GT:dbCAN_4 0.1200677976 0.9999999
## PL:dbCAN_4:HMMER-GT:dbCAN_4 0.2572360283 1.0000000
## CE:dbCAN_4:HMMER-GT:dbCAN_4 0.2257578630 1.0000000
## AA:dbCAN_4:HMMER-GT:dbCAN_4 0.2805598870 1.0000000
## CBM:dbCAN_4:HMMER-GT:dbCAN_4 0.0016454851 0.0560631
## GH:dbCAN_4:DIAMOND-GT:dbCAN_4 0.1858214186 1.0000000
## GT:dbCAN_4:DIAMOND-GT:dbCAN_4 0.1922406936 1.0000000
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4 0.3115838543 0.9999999
## CE:dbCAN_4:DIAMOND-GT:dbCAN_4 0.3357065512 1.0000000
## AA:dbCAN_4:DIAMOND-GT:dbCAN_4 0.3288064148 1.0000000
## CBM:dbCAN_4:DIAMOND-GT:dbCAN_4 0.1525727578 1.0000000
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4 0.1459385026 1.0000000
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4 0.1667063773 1.0000000
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4 0.2579261594 1.0000000
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4 0.2374604148 1.0000000
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4 0.2813932203 1.0000000
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4 0.0716645692 0.9083409
## GH:CUPP-GT:dbCAN_4 0.0214411234 0.2447515
## GT:CUPP-GT:dbCAN_4 0.0607285007 0.8483847
## PL:CUPP-GT:dbCAN_4 0.0391545928 0.2782800
## CE:CUPP-GT:dbCAN_4 0.1065435249 0.8928689
## AA:CUPP-GT:dbCAN_4 0.0661705896 0.4837351
## CBM:CUPP-GT:dbCAN_4 -0.7285605322 0.0000000
## CE:dbCAN_4-PL:dbCAN_4 0.2771068449 1.0000000
## AA:dbCAN_4-PL:dbCAN_4 0.3211259002 1.0000000
## CBM:dbCAN_4-PL:dbCAN_4 0.1642255445 0.9999812
## GH:dbCAN_4:HMMER-PL:dbCAN_4 0.1946278647 1.0000000
## GT:dbCAN_4:HMMER-PL:dbCAN_4 0.1850907690 1.0000000
## PL:dbCAN_4:HMMER-PL:dbCAN_4 0.3027231397 1.0000000
## CE:dbCAN_4:HMMER-PL:dbCAN_4 0.2667931820 1.0000000
## AA:dbCAN_4:HMMER-PL:dbCAN_4 0.3194592335 1.0000000
## CBM:dbCAN_4:HMMER-PL:dbCAN_4 0.0621706113 0.5151583
## GH:dbCAN_4:DIAMOND-PL:dbCAN_4 0.2572524173 1.0000000
## GT:dbCAN_4:DIAMOND-PL:dbCAN_4 0.2570909326 1.0000000
## PL:dbCAN_4:DIAMOND-PL:dbCAN_4 0.3570709658 1.0000000
## CE:dbCAN_4:DIAMOND-PL:dbCAN_4 0.3757040830 1.0000000
## AA:dbCAN_4:DIAMOND-PL:dbCAN_4 0.3677057613 1.0000000
## CBM:dbCAN_4:DIAMOND-PL:dbCAN_4 0.2128260740 1.0000000
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4 0.2175803024 1.0000000
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4 0.2315566163 1.0000000
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4 0.3034132709 1.0000000
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4 0.2784957338 1.0000000
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4 0.3202925668 1.0000000
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4 0.1321896955 0.9951233
## GH:CUPP-PL:dbCAN_4 0.0928721221 0.9153066
## GT:CUPP-PL:dbCAN_4 0.1254026489 0.9938389
## PL:CUPP-PL:dbCAN_4 0.0846417043 0.6240372
## CE:CUPP-PL:dbCAN_4 0.1465410567 0.9650017
## AA:CUPP-PL:dbCAN_4 0.1050699361 0.7268862
## CBM:CUPP-PL:dbCAN_4 -0.6683072160 0.0000000
## AA:dbCAN_4-CE:dbCAN_4 0.3856102980 1.0000000
## CBM:dbCAN_4-CE:dbCAN_4 0.2340880237 1.0000000
## GH:dbCAN_4:HMMER-CE:dbCAN_4 0.2666519564 1.0000000
## GT:dbCAN_4:HMMER-CE:dbCAN_4 0.2558712255 1.0000000
## PL:dbCAN_4:HMMER-CE:dbCAN_4 0.3690177795 1.0000000
## CE:dbCAN_4:HMMER-CE:dbCAN_4 0.3318810416 1.0000000
## AA:dbCAN_4:HMMER-CE:dbCAN_4 0.3839436313 1.0000000
## CBM:dbCAN_4:HMMER-CE:dbCAN_4 0.1320330906 0.9821525
## GH:dbCAN_4:DIAMOND-CE:dbCAN_4 0.3292273760 0.9999999
## GT:dbCAN_4:DIAMOND-CE:dbCAN_4 0.3278373649 1.0000000
## PL:dbCAN_4:DIAMOND-CE:dbCAN_4 0.4233656056 0.9999989
## CE:dbCAN_4:DIAMOND-CE:dbCAN_4 0.4405007157 1.0000000
## AA:dbCAN_4:DIAMOND-CE:dbCAN_4 0.4321901591 1.0000000
## CBM:dbCAN_4:DIAMOND-CE:dbCAN_4 0.2826309261 1.0000000
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4 0.2895923521 1.0000000
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4 0.3023030486 1.0000000
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4 0.3697079107 1.0000000
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4 0.3435835934 1.0000000
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4 0.3847769646 1.0000000
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4 0.2020521747 0.9999999
## GH:CUPP-CE:dbCAN_4 0.1648470808 0.9999734
## GT:CUPP-CE:dbCAN_4 0.1961142953 0.9999999
## PL:CUPP-CE:dbCAN_4 0.1509363441 0.9784798
## CE:CUPP-CE:dbCAN_4 0.2113376894 0.9998606
## AA:CUPP-CE:dbCAN_4 0.1695543339 0.9847280
## CBM:CUPP-CE:dbCAN_4 -0.5985023638 0.0000000
## CBM:dbCAN_4-AA:dbCAN_4 0.2140625117 1.0000000
## GH:dbCAN_4:HMMER-AA:dbCAN_4 0.2476242806 1.0000000
## GT:dbCAN_4:HMMER-AA:dbCAN_4 0.2362738670 1.0000000
## PL:dbCAN_4:HMMER-AA:dbCAN_4 0.3472686946 1.0000000
## CE:dbCAN_4:HMMER-AA:dbCAN_4 0.3095284948 1.0000000
## AA:dbCAN_4:HMMER-AA:dbCAN_4 0.3612856274 1.0000000
## CBM:dbCAN_4:HMMER-AA:dbCAN_4 0.1120075785 0.8895391
## GH:dbCAN_4:DIAMOND-AA:dbCAN_4 0.3101774221 1.0000000
## GT:dbCAN_4:DIAMOND-AA:dbCAN_4 0.3082242524 1.0000000
## PL:dbCAN_4:DIAMOND-AA:dbCAN_4 0.4016165207 1.0000000
## CE:dbCAN_4:DIAMOND-AA:dbCAN_4 0.4180010595 1.0000000
## AA:dbCAN_4:DIAMOND-AA:dbCAN_4 0.4095321552 1.0000000
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4 0.2625783223 1.0000000
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4 0.2705592178 1.0000000
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4 0.2826899361 1.0000000
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4 0.3479588257 1.0000000
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4 0.3212310466 1.0000000
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4 0.3621189608 1.0000000
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4 0.1820266627 0.9999410
## GH:CUPP-AA:dbCAN_4 0.1457971269 0.9972571
## GT:CUPP-AA:dbCAN_4 0.1764850668 0.9999370
## PL:CUPP-AA:dbCAN_4 0.1291872591 0.8924054
## CE:CUPP-AA:dbCAN_4 0.1888380332 0.9962669
## AA:CUPP-AA:dbCAN_4 0.1468963301 0.9205568
## CBM:CUPP-AA:dbCAN_4 -0.6185549677 0.0000000
## GH:dbCAN_4:HMMER-CBM:dbCAN_4 0.2160401547 0.9999959
## GT:dbCAN_4:HMMER-CBM:dbCAN_4 0.2114615188 1.0000000
## PL:dbCAN_4:HMMER-CBM:dbCAN_4 0.3442618008 0.9999812
## CE:dbCAN_4:HMMER-CBM:dbCAN_4 0.3118996824 1.0000000
## AA:dbCAN_4:HMMER-CBM:dbCAN_4 0.3662893069 1.0000000
## CBM:dbCAN_4:HMMER-CBM:dbCAN_4 0.0919512286 0.9818216
## GH:dbCAN_4:DIAMOND-CBM:dbCAN_4 0.2788689829 0.6586149
## GT:dbCAN_4:DIAMOND-CBM:dbCAN_4 0.2835915789 0.9520349
## PL:dbCAN_4:DIAMOND-CBM:dbCAN_4 0.3986096269 0.9527873
## CE:dbCAN_4:DIAMOND-CBM:dbCAN_4 0.4216470968 0.9946057
## AA:dbCAN_4:DIAMOND-CBM:dbCAN_4 0.4145358347 0.9993695
## CBM:dbCAN_4:DIAMOND-CBM:dbCAN_4 0.2428145186 1.0000000
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 0.2390427272 0.9965374
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 0.2580572626 0.9992888
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 0.3449519319 0.9999780
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 0.3236022343 1.0000000
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 0.3671226403 1.0000000
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 0.1619703128 1.0000000
## GH:CUPP-CBM:dbCAN_4 0.1144886877 0.9999996
## GT:CUPP-CBM:dbCAN_4 0.1520358066 1.0000000
## PL:CUPP-CBM:dbCAN_4 0.1261803653 0.9900371
## CE:CUPP-CBM:dbCAN_4 0.1924840705 0.9999974
## AA:CUPP-CBM:dbCAN_4 0.1519000095 0.9954339
## CBM:CUPP-CBM:dbCAN_4 -0.6383187714 0.0000000
## GT:dbCAN_4:HMMER-GH:dbCAN_4:HMMER 0.1234487332 1.0000000
## PL:dbCAN_4:HMMER-GH:dbCAN_4:HMMER 0.2675516839 1.0000000
## CE:dbCAN_4:HMMER-GH:dbCAN_4:HMMER 0.2373511781 1.0000000
## AA:dbCAN_4:HMMER-GH:dbCAN_4:HMMER 0.2927386387 1.0000000
## CBM:dbCAN_4:HMMER-GH:dbCAN_4:HMMER 0.0068727845 0.0837400
## GH:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 0.1861886509 0.9908011
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 0.1956961803 0.9999937
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 0.3218995100 0.9998487
## CE:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 0.3475863900 0.9999982
## AA:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 0.3409851665 1.0000000
## CBM:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 0.1579057600 1.0000000
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 0.1461973216 1.0000000
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 0.1701618640 1.0000000
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 0.2682418150 1.0000000
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 0.2490537299 1.0000000
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 0.2935719721 1.0000000
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 0.0768918687 0.9814804
## GH:CUPP-GH:dbCAN_4:HMMER 0.0218083556 0.3167915
## GT:CUPP-GH:dbCAN_4:HMMER 0.0642596676 0.9571742
## PL:CUPP-GH:dbCAN_4:HMMER 0.0494702484 0.4227726
## CE:CUPP-GH:dbCAN_4:HMMER 0.1184233637 0.9670116
## AA:CUPP-GH:dbCAN_4:HMMER 0.0783493413 0.6529684
## CBM:CUPP-GH:dbCAN_4:HMMER -0.7232275300 0.0000000
## PL:dbCAN_4:HMMER-GT:dbCAN_4:HMMER 0.3027917465 1.0000000
## CE:dbCAN_4:HMMER-GT:dbCAN_4:HMMER 0.2713476054 1.0000000
## AA:dbCAN_4:HMMER-GT:dbCAN_4:HMMER 0.3261653835 1.0000000
## CBM:dbCAN_4:HMMER-GT:dbCAN_4:HMMER 0.0470713069 0.5666515
## GH:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 0.2311330683 0.9438016
## GT:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 0.2376236795 0.9991564
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 0.3571395726 0.9971417
## CE:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 0.3813039916 0.9998925
## AA:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 0.3744119113 0.9999964
## CBM:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 0.1980011769 1.0000000
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 0.1912477284 0.9999990
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 0.2120893632 0.9999999
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 0.3034818776 1.0000000
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 0.2830501572 1.0000000
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 0.3269987168 1.0000000
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 0.1170903911 0.9999847
## GH:CUPP-GT:dbCAN_4:HMMER 0.0667527731 0.9714439
## GT:CUPP-GT:dbCAN_4:HMMER 0.1061132886 0.9999688
## PL:CUPP-GT:dbCAN_4:HMMER 0.0847103110 0.8121948
## CE:CUPP-GT:dbCAN_4:HMMER 0.1521409653 0.9984582
## AA:CUPP-GT:dbCAN_4:HMMER 0.1117760861 0.9081928
## CBM:CUPP-GT:dbCAN_4:HMMER -0.6831321131 0.0000000
## CE:dbCAN_4:HMMER-PL:dbCAN_4:HMMER 0.2667931820 1.0000000
## AA:dbCAN_4:HMMER-PL:dbCAN_4:HMMER 0.3194592335 1.0000000
## CBM:dbCAN_4:HMMER-PL:dbCAN_4:HMMER 0.0621706113 0.5151583
## GH:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 0.2572524173 1.0000000
## GT:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 0.2570909326 1.0000000
## PL:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 0.3570709658 1.0000000
## CE:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 0.3757040830 1.0000000
## AA:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 0.3677057613 1.0000000
## CBM:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 0.2128260740 1.0000000
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 0.2175803024 1.0000000
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 0.2315566163 1.0000000
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 0.3034132709 1.0000000
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 0.2784957338 1.0000000
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 0.3202925668 1.0000000
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 0.1321896955 0.9951233
## GH:CUPP-PL:dbCAN_4:HMMER 0.0928721221 0.9153066
## GT:CUPP-PL:dbCAN_4:HMMER 0.1254026489 0.9938389
## PL:CUPP-PL:dbCAN_4:HMMER 0.0846417043 0.6240372
## CE:CUPP-PL:dbCAN_4:HMMER 0.1465410567 0.9650017
## AA:CUPP-PL:dbCAN_4:HMMER 0.1050699361 0.7268862
## CBM:CUPP-PL:dbCAN_4:HMMER -0.6683072160 0.0000000
## AA:dbCAN_4:HMMER-CE:dbCAN_4:HMMER 0.3942572942 1.0000000
## CBM:dbCAN_4:HMMER-CE:dbCAN_4:HMMER 0.1423467535 0.9936970
## GH:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 0.3395410390 0.9999981
## GT:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 0.3381510279 1.0000000
## PL:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 0.4336792686 0.9999907
## CE:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 0.4508143787 0.9999996
## AA:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 0.4425038220 1.0000000
## CBM:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 0.2929445891 1.0000000
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 0.2999060150 1.0000000
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 0.3126167116 1.0000000
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 0.3800215736 1.0000000
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 0.3538972564 1.0000000
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 0.3950906276 1.0000000
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 0.2123658377 1.0000000
## GH:CUPP-CE:dbCAN_4:HMMER 0.1751607437 0.9999979
## GT:CUPP-CE:dbCAN_4:HMMER 0.2064279582 1.0000000
## PL:CUPP-CE:dbCAN_4:HMMER 0.1612500070 0.9908145
## CE:CUPP-CE:dbCAN_4:HMMER 0.2216513524 0.9999710
## AA:CUPP-CE:dbCAN_4:HMMER 0.1798679969 0.9933348
## CBM:CUPP-CE:dbCAN_4:HMMER -0.5881887009 0.0000000
## CBM:dbCAN_4:HMMER-AA:dbCAN_4:HMMER 0.1136742452 0.8991897
## GH:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 0.3118440888 1.0000000
## GT:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 0.3098909191 1.0000000
## PL:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 0.4032831873 1.0000000
## CE:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 0.4196677262 1.0000000
## AA:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 0.4111988219 1.0000000
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 0.2642449889 1.0000000
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 0.2722258845 1.0000000
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 0.2843566028 1.0000000
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 0.3496254924 1.0000000
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 0.3228977133 1.0000000
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 0.3637856274 1.0000000
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 0.1836933294 0.9999567
## GH:CUPP-AA:dbCAN_4:HMMER 0.1474637935 0.9977928
## GT:CUPP-AA:dbCAN_4:HMMER 0.1781517335 0.9999541
## PL:CUPP-AA:dbCAN_4:HMMER 0.1308539258 0.9006972
## CE:CUPP-AA:dbCAN_4:HMMER 0.1905046999 0.9968100
## AA:CUPP-AA:dbCAN_4:HMMER 0.1485629967 0.9267882
## CBM:CUPP-AA:dbCAN_4:HMMER -0.6168883010 0.0000000
## GH:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 0.3809239161 0.0002430
## GT:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 0.3856465120 0.0076763
## PL:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 0.5006645600 0.0730613
## CE:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 0.5237020299 0.2723381
## AA:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 0.5165907678 0.4548275
## CBM:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 0.3448694517 0.4717183
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 0.3410976603 0.0131990
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 0.3601121957 0.0553995
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 0.4470068650 0.5067566
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 0.4256571674 0.9797606
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 0.4691775734 0.8944353
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 0.2640252459 0.9999720
## GH:CUPP-CBM:dbCAN_4:HMMER 0.2165436208 0.9999965
## GT:CUPP-CBM:dbCAN_4:HMMER 0.2540907397 0.9997728
## PL:CUPP-CBM:dbCAN_4:HMMER 0.2282352984 1.0000000
## CE:CUPP-CBM:dbCAN_4:HMMER 0.2945390036 1.0000000
## AA:CUPP-CBM:dbCAN_4:HMMER 0.2539549427 1.0000000
## CBM:CUPP-CBM:dbCAN_4:HMMER -0.5362638383 0.0000000
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND 0.1343221365 1.0000000
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND 0.2602460569 1.0000000
## CE:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND 0.2858728830 1.0000000
## AA:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND 0.2792603024 1.0000000
## CBM:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND 0.0964521738 0.9996214
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 0.0849654897 0.9999983
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 0.1087878202 1.0000000
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 0.2065883620 1.0000000
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 0.1873511438 0.9999999
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 0.2318471079 1.0000000
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 0.0154426912 0.1492906
## GH:CUPP-GH:dbCAN_4:DIAMOND -0.0394284561 0.0003458
## GT:CUPP-GH:dbCAN_4:DIAMOND 0.0028823648 0.0637442
## PL:CUPP-GH:dbCAN_4:DIAMOND -0.0121832046 0.0248965
## CE:CUPP-GH:dbCAN_4:DIAMOND 0.0567098567 0.4244734
## AA:CUPP-GH:dbCAN_4:DIAMOND 0.0166244772 0.1040589
## CBM:CUPP-GH:dbCAN_4:DIAMOND -0.7846811162 0.0000000
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4:DIAMOND 0.2858770946 1.0000000
## CE:dbCAN_4:DIAMOND-GT:dbCAN_4:DIAMOND 0.3099997914 1.0000000
## AA:dbCAN_4:DIAMOND-GT:dbCAN_4:DIAMOND 0.3030996550 1.0000000
## CBM:dbCAN_4:DIAMOND-GT:dbCAN_4:DIAMOND 0.1268659980 0.9999994
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 0.1202317428 1.0000000
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 0.1409996175 1.0000000
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 0.2322193996 1.0000000
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 0.2117536550 1.0000000
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 0.2556864605 1.0000000
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 0.0459578094 0.5452166
## GH:CUPP-GT:dbCAN_4:DIAMOND -0.0042656364 0.0343079
## GT:CUPP-GT:dbCAN_4:DIAMOND 0.0350217409 0.4096871
## PL:CUPP-GT:dbCAN_4:DIAMOND 0.0134478330 0.0970090
## CE:CUPP-GT:dbCAN_4:DIAMOND 0.0808367651 0.6661997
## AA:CUPP-GT:dbCAN_4:DIAMOND 0.0404638298 0.2396352
## CBM:CUPP-GT:dbCAN_4:DIAMOND -0.7542672920 0.0000000
## CE:dbCAN_4:DIAMOND-PL:dbCAN_4:DIAMOND 0.3213562569 1.0000000
## AA:dbCAN_4:DIAMOND-PL:dbCAN_4:DIAMOND 0.3133579352 1.0000000
## CBM:dbCAN_4:DIAMOND-PL:dbCAN_4:DIAMOND 0.1584782479 0.9999278
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 0.1632324763 0.9999997
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 0.1772087903 0.9999999
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 0.2490654448 1.0000000
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 0.2241479077 0.9999992
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 0.2659447407 1.0000000
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 0.0778418694 0.7034794
## GH:CUPP-PL:dbCAN_4:DIAMOND 0.0385242960 0.2930330
## GT:CUPP-PL:dbCAN_4:DIAMOND 0.0710548228 0.6568690
## PL:CUPP-PL:dbCAN_4:DIAMOND 0.0302938782 0.1578879
## CE:CUPP-PL:dbCAN_4:DIAMOND 0.0921932306 0.6276475
## AA:CUPP-PL:dbCAN_4:DIAMOND 0.0507221100 0.2584791
## CBM:CUPP-PL:dbCAN_4:DIAMOND -0.7226550421 0.0000000
## AA:dbCAN_4:DIAMOND-CE:dbCAN_4:DIAMOND 0.3437286533 1.0000000
## CBM:dbCAN_4:DIAMOND-CE:dbCAN_4:DIAMOND 0.1954310635 0.9999986
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 0.2028908176 1.0000000
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 0.2153176663 1.0000000
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 0.2816847411 1.0000000
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 0.2552691970 1.0000000
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 0.2963154588 1.0000000
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 0.1148655186 0.9196317
## GH:CUPP-CE:dbCAN_4:DIAMOND 0.0781373013 0.6729378
## GT:CUPP-CE:dbCAN_4:DIAMOND 0.1091210389 0.9072879
## PL:CUPP-CE:dbCAN_4:DIAMOND 0.0629131745 0.3587932
## CE:CUPP-CE:dbCAN_4:DIAMOND 0.1229524197 0.8167165
## AA:CUPP-CE:dbCAN_4:DIAMOND 0.0810928281 0.4607328
## CBM:CUPP-CE:dbCAN_4:DIAMOND -0.6857022265 0.0000000
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND 0.2159984612 1.0000000
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 0.2239793567 1.0000000
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 0.2361100750 1.0000000
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 0.3013789646 1.0000000
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 0.2746511855 1.0000000
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 0.3155390997 1.0000000
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 0.1354468016 0.9775303
## GH:CUPP-AA:dbCAN_4:DIAMOND 0.0992172658 0.8527308
## GT:CUPP-AA:dbCAN_4:DIAMOND 0.1299052057 0.9741063
## PL:CUPP-AA:dbCAN_4:DIAMOND 0.0826073980 0.5233785
## CE:CUPP-AA:dbCAN_4:DIAMOND 0.1422581721 0.9105515
## AA:CUPP-AA:dbCAN_4:DIAMOND 0.1003164689 0.6141581
## CBM:CUPP-AA:dbCAN_4:DIAMOND -0.6651348288 0.0000000
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 0.1921626746 1.0000000
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 0.2110725906 1.0000000
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 0.2976954499 1.0000000
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 0.2762881252 1.0000000
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 0.3197814393 1.0000000
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 0.1149216581 0.9996591
## GH:CUPP-CBM:dbCAN_4:DIAMOND 0.0676053098 0.9298550
## GT:CUPP-CBM:dbCAN_4:DIAMOND 0.1050484902 0.9993927
## PL:CUPP-CBM:dbCAN_4:DIAMOND 0.0789238833 0.7133457
## CE:CUPP-CBM:dbCAN_4:DIAMOND 0.1451567549 0.9932548
## AA:CUPP-CBM:dbCAN_4:DIAMOND 0.1045588086 0.8379320
## CBM:CUPP-CBM:dbCAN_4:DIAMOND -0.6853713806 0.0000000
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub 0.1475157201 1.0000000
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub 0.2455270629 1.0000000
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub 0.2263269357 1.0000000
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub 0.2708397195 1.0000000
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub 0.0542272513 0.7779855
## GH:CUPP-GH:dbCAN_4:dbCAN-sub -0.0008039897 0.0460409
## GT:CUPP-GH:dbCAN_4:dbCAN-sub 0.0416127219 0.6331051
## PL:CUPP-GH:dbCAN_4:dbCAN-sub 0.0267554963 0.1847144
## CE:CUPP-GH:dbCAN_4:dbCAN-sub 0.0956938936 0.8466939
## AA:CUPP-GH:dbCAN_4:dbCAN-sub 0.0556170888 0.3968040
## CBM:CUPP-GH:dbCAN_4:dbCAN-sub -0.7458932307 0.0000000
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:dbCAN-sub 0.2577537159 1.0000000
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4:dbCAN-sub 0.2372879713 1.0000000
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4:dbCAN-sub 0.2812207768 1.0000000
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4:dbCAN-sub 0.0714921257 0.9068676
## GH:CUPP-GT:dbCAN_4:dbCAN-sub 0.0212686799 0.2421837
## GT:CUPP-GT:dbCAN_4:dbCAN-sub 0.0605560572 0.8462063
## PL:CUPP-GT:dbCAN_4:dbCAN-sub 0.0389821493 0.2766000
## CE:CUPP-GT:dbCAN_4:dbCAN-sub 0.1063710814 0.8918004
## AA:CUPP-GT:dbCAN_4:dbCAN-sub 0.0659981461 0.4818650
## CBM:CUPP-GT:dbCAN_4:dbCAN-sub -0.7287329757 0.0000000
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4:dbCAN-sub 0.2778056027 1.0000000
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4:dbCAN-sub 0.3196024357 1.0000000
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4:dbCAN-sub 0.1314995644 0.9946834
## GH:CUPP-PL:dbCAN_4:dbCAN-sub 0.0921819909 0.9108886
## GT:CUPP-PL:dbCAN_4:dbCAN-sub 0.1247125177 0.9932823
## PL:CUPP-PL:dbCAN_4:dbCAN-sub 0.0839515732 0.6170270
## CE:CUPP-PL:dbCAN_4:dbCAN-sub 0.1458509255 0.9633544
## AA:CUPP-PL:dbCAN_4:dbCAN-sub 0.1043798050 0.7210747
## CBM:CUPP-PL:dbCAN_4:dbCAN-sub -0.6689973471 0.0000000
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4:dbCAN-sub 0.3833880757 1.0000000
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4:dbCAN-sub 0.2006632859 0.9999999
## GH:CUPP-CE:dbCAN_4:dbCAN-sub 0.1634581919 0.9999639
## GT:CUPP-CE:dbCAN_4:dbCAN-sub 0.1947254064 0.9999999
## PL:CUPP-CE:dbCAN_4:dbCAN-sub 0.1495474552 0.9761123
## CE:CUPP-CE:dbCAN_4:dbCAN-sub 0.2099488005 0.9998306
## AA:CUPP-CE:dbCAN_4:dbCAN-sub 0.1681654450 0.9830785
## CBM:CUPP-CE:dbCAN_4:dbCAN-sub -0.5998912527 0.0000000
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub 0.1828599961 0.9999494
## GH:CUPP-AA:dbCAN_4:dbCAN-sub 0.1466304602 0.9975375
## GT:CUPP-AA:dbCAN_4:dbCAN-sub 0.1773184001 0.9999462
## PL:CUPP-AA:dbCAN_4:dbCAN-sub 0.1300205924 0.8966050
## CE:CUPP-AA:dbCAN_4:dbCAN-sub 0.1896713665 0.9965476
## AA:CUPP-AA:dbCAN_4:dbCAN-sub 0.1477296634 0.9237162
## CBM:CUPP-AA:dbCAN_4:dbCAN-sub -0.6177216344 0.0000000
## GH:CUPP-CBM:dbCAN_4:dbCAN-sub 0.1465245366 1.0000000
## GT:CUPP-CBM:dbCAN_4:dbCAN-sub 0.1840716555 1.0000000
## PL:CUPP-CBM:dbCAN_4:dbCAN-sub 0.1582162143 0.9999301
## CE:CUPP-CBM:dbCAN_4:dbCAN-sub 0.2245199195 1.0000000
## AA:CUPP-CBM:dbCAN_4:dbCAN-sub 0.1839358585 0.9999586
## CBM:CUPP-CBM:dbCAN_4:dbCAN-sub -0.6062829224 0.0000000
## GT:CUPP-GH:CUPP 0.1672626601 1.0000000
## PL:CUPP-GH:CUPP 0.1521970906 0.9999905
## CE:CUPP-GH:CUPP 0.2210901520 1.0000000
## AA:CUPP-GH:CUPP 0.1810047724 0.9999948
## CBM:CUPP-GH:CUPP -0.6203008209 0.0000000
## PL:CUPP-GT:CUPP 0.1458923171 0.9997472
## CE:CUPP-GT:CUPP 0.2132385892 1.0000000
## AA:CUPP-GT:CUPP 0.1728574120 0.9998783
## CBM:CUPP-GT:CUPP -0.6216929409 0.0000000
## CE:CUPP-PL:CUPP 0.3646224921 1.0000000
## AA:CUPP-PL:CUPP 0.3231513716 1.0000000
## CBM:CUPP-PL:CUPP -0.4502257805 0.0000000
## AA:CUPP-CE:CUPP 0.3102558544 1.0000000
## CBM:CUPP-CE:CUPP -0.4565392002 0.0000000
## CBM:CUPP-AA:CUPP -0.4024990036 0.000000010.2.4 Precision
| CAZy_class | Prediction_tool | Mean | Standard Deviation | Lower CI | Upper CI |
|---|---|---|---|---|---|
| GH | dbCAN_4 | 0.9245 | 0.2397 | 0.8840 | 0.9650 |
| GH | dbCAN_4:HMMER | 0.9102 | 0.2626 | 0.8662 | 0.9543 |
| GH | dbCAN_4:DIAMOND | 0.9509 | 0.1762 | 0.9209 | 0.9809 |
| GH | dbCAN_4:dbCAN-sub | 0.9127 | 0.2535 | 0.8700 | 0.9553 |
| GH | CUPP | 0.8331 | 0.3615 | 0.7715 | 0.8946 |
| GT | dbCAN_4 | 0.8953 | 0.2508 | 0.8380 | 0.9526 |
| GT | dbCAN_4:HMMER | 0.8646 | 0.2758 | 0.8020 | 0.9272 |
| GT | dbCAN_4:DIAMOND | 0.9360 | 0.1985 | 0.8907 | 0.9814 |
| GT | dbCAN_4:dbCAN-sub | 0.8940 | 0.2511 | 0.8366 | 0.9513 |
| GT | CUPP | 0.8785 | 0.2933 | 0.8110 | 0.9460 |
| PL | dbCAN_4 | 0.9210 | 0.2293 | 0.8219 | 1.0202 |
| PL | dbCAN_4:HMMER | 0.9210 | 0.2293 | 0.8219 | 1.0202 |
| PL | dbCAN_4:DIAMOND | 0.9329 | 0.1638 | 0.8620 | 1.0037 |
| PL | dbCAN_4:dbCAN-sub | 0.9211 | 0.2293 | 0.8219 | 1.0202 |
| PL | CUPP | 0.7796 | 0.4203 | 0.5979 | 0.9614 |
| CE | dbCAN_4 | 0.7625 | 0.3416 | 0.5927 | 0.9324 |
| CE | dbCAN_4:HMMER | 0.7511 | 0.3412 | 0.5814 | 0.9208 |
| CE | dbCAN_4:DIAMOND | 0.8751 | 0.2163 | 0.7639 | 0.9863 |
| CE | dbCAN_4:dbCAN-sub | 0.7613 | 0.3408 | 0.5918 | 0.9307 |
| CE | CUPP | 0.6687 | 0.4313 | 0.4470 | 0.8905 |
| AA | dbCAN_4 | 0.8381 | 0.2675 | 0.6956 | 0.9806 |
| AA | dbCAN_4:HMMER | 0.8322 | 0.2712 | 0.6877 | 0.9767 |
| AA | dbCAN_4:DIAMOND | 0.8553 | 0.1790 | 0.7600 | 0.9507 |
| AA | dbCAN_4:dbCAN-sub | 0.8348 | 0.2690 | 0.6915 | 0.9781 |
| AA | CUPP | 0.6511 | 0.4322 | 0.4207 | 0.8814 |
| CBM | dbCAN_4 | 0.8451 | 0.3412 | 0.7537 | 0.9364 |
| CBM | dbCAN_4:HMMER | 0.8028 | 0.3786 | 0.7014 | 0.9042 |
| CBM | dbCAN_4:DIAMOND | 0.8676 | 0.2812 | 0.7916 | 0.9436 |
| CBM | dbCAN_4:dbCAN-sub | 0.8212 | 0.3608 | 0.7246 | 0.9179 |
| CBM | CUPP | 0.0000 | 0.0000 | 0.0000 | 0.0000 |
Figure 10.7: 95% confidence intervals of the precision of CAZy family classification across all CAZy families per CAZy class, for each CAZyme classifier.
Figure 10.8: Scatter plot of overlaying a one-dimensional box-and-whisker plot of precision for each CAZy family for each CAZyme classifier. Each CAZy family is represented as a single point on the plot.
Test for significant differences between the means of the tools using a one-way ANOVA.
## Df Sum Sq Mean Sq F value Pr(>F)
## Prediction_tool 4 12.05 3.0125 31.17 <2e-16 ***
## Residuals 1620 156.56 0.0966
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1The means are statistically significantly different, therefore, use a post hoc Turkey HSD test to determine between which tools the means are significantly difference.
## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistical_parameter ~ Prediction_tool, data = fam_subset_prec_all)
##
## $Prediction_tool
## diff lwr upr
## dbCAN_4:HMMER-dbCAN_4 -0.021109181 -0.08745209 0.04523373
## dbCAN_4:DIAMOND-dbCAN_4 0.032489415 -0.03421144 0.09919027
## dbCAN_4:dbCAN-sub-dbCAN_4 -0.009528269 -0.07597208 0.05691554
## CUPP-dbCAN_4 -0.211296307 -0.27804941 -0.14454321
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.053598595 -0.01295097 0.12014816
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.011580912 -0.05471103 0.07787285
## CUPP-dbCAN_4:HMMER -0.190187127 -0.25678906 -0.12358519
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND -0.042017683 -0.10866784 0.02463247
## CUPP-dbCAN_4:DIAMOND -0.243785722 -0.31074421 -0.17682723
## CUPP-dbCAN_4:dbCAN-sub -0.201768038 -0.26847048 -0.13506560
## p adj
## dbCAN_4:HMMER-dbCAN_4 0.9082687
## dbCAN_4:DIAMOND-dbCAN_4 0.6723764
## dbCAN_4:dbCAN-sub-dbCAN_4 0.9950321
## CUPP-dbCAN_4 0.0000000
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.1803600
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.9894272
## CUPP-dbCAN_4:HMMER 0.0000000
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND 0.4208554
## CUPP-dbCAN_4:DIAMOND 0.0000000
## CUPP-dbCAN_4:dbCAN-sub 0.0000000Now test for statistically significant differences between CAZy classes using a two-way ANOVA.
## Df Sum Sq Mean Sq F value Pr(>F)
## CAZy_class 5 13.07 2.6149 34.12 <2e-16 ***
## Prediction_tool 4 12.05 3.0134 39.32 <2e-16 ***
## CAZy_class:Prediction_tool 20 21.25 1.0625 13.86 <2e-16 ***
## Residuals 1595 122.23 0.0766
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1Statistically significant difference was detected so follow up with a Tukey test to determine if there are differences between specific groups.
## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistical_parameter ~ CAZy_class * Prediction_tool, data = fam_subset_prec_all)
##
## $`CAZy_class:Prediction_tool`
## diff lwr
## GT:dbCAN_4-GH:dbCAN_4 -2.915379e-02 -0.17785549
## PL:dbCAN_4-GH:dbCAN_4 -3.450193e-03 -0.23772684
## CE:dbCAN_4-GH:dbCAN_4 -1.619765e-01 -0.42262935
## AA:dbCAN_4-GH:dbCAN_4 -8.640648e-02 -0.36108118
## CBM:dbCAN_4-GH:dbCAN_4 -7.943309e-02 -0.24433192
## GH:dbCAN_4:HMMER-GH:dbCAN_4 -1.428696e-02 -0.13945115
## GT:dbCAN_4:HMMER-GH:dbCAN_4 -5.988449e-02 -0.20796382
## PL:dbCAN_4:HMMER-GH:dbCAN_4 -3.450193e-03 -0.23772684
## CE:dbCAN_4:HMMER-GH:dbCAN_4 -1.734262e-01 -0.43407904
## AA:dbCAN_4:HMMER-GH:dbCAN_4 -9.226747e-02 -0.36694217
## CBM:dbCAN_4:HMMER-GH:dbCAN_4 -1.216715e-01 -0.28657035
## GH:dbCAN_4:DIAMOND-GH:dbCAN_4 2.638812e-02 -0.09969313
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4 1.153600e-02 -0.13716570
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4 8.351049e-03 -0.22592560
## CE:dbCAN_4:DIAMOND-GH:dbCAN_4 -4.942024e-02 -0.31676325
## AA:dbCAN_4:DIAMOND-GH:dbCAN_4 -6.915755e-02 -0.34383224
## CBM:dbCAN_4:DIAMOND-GH:dbCAN_4 -5.688814e-02 -0.22284767
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4 -1.184846e-02 -0.13723754
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4 -3.054262e-02 -0.17924432
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4 -3.439410e-03 -0.23771606
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4 -1.632331e-01 -0.42388596
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4 -8.970294e-02 -0.36437763
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4 -1.032520e-01 -0.26815085
## GH:CUPP-GH:dbCAN_4 -9.144272e-02 -0.21752396
## GT:CUPP-GH:dbCAN_4 -4.600642e-02 -0.19534438
## PL:CUPP-GH:dbCAN_4 -1.448801e-01 -0.37915674
## CE:CUPP-GH:dbCAN_4 -2.557758e-01 -0.52311883
## AA:CUPP-GH:dbCAN_4 -2.734380e-01 -0.54811275
## CBM:CUPP-GH:dbCAN_4 -9.244992e-01 -1.09045872
## PL:dbCAN_4-GT:dbCAN_4 2.570359e-02 -0.22171942
## CE:dbCAN_4-GT:dbCAN_4 -1.328227e-01 -0.40535254
## AA:dbCAN_4-GT:dbCAN_4 -5.725270e-02 -0.34322261
## CBM:dbCAN_4-GT:dbCAN_4 -5.027931e-02 -0.23337552
## GH:dbCAN_4:HMMER-GT:dbCAN_4 1.486682e-02 -0.13345268
## GT:dbCAN_4:HMMER-GT:dbCAN_4 -3.073070e-02 -0.19883808
## PL:dbCAN_4:HMMER-GT:dbCAN_4 2.570359e-02 -0.22171942
## CE:dbCAN_4:HMMER-GT:dbCAN_4 -1.442724e-01 -0.41680224
## AA:dbCAN_4:HMMER-GT:dbCAN_4 -6.311369e-02 -0.34908360
## CBM:dbCAN_4:HMMER-GT:dbCAN_4 -9.251774e-02 -0.27561395
## GH:dbCAN_4:DIAMOND-GT:dbCAN_4 5.554190e-02 -0.09355230
## GT:dbCAN_4:DIAMOND-GT:dbCAN_4 4.068978e-02 -0.12796607
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4 3.750483e-02 -0.20991818
## CE:dbCAN_4:DIAMOND-GT:dbCAN_4 -2.026645e-02 -0.29920172
## AA:dbCAN_4:DIAMOND-GT:dbCAN_4 -4.000376e-02 -0.32597367
## CBM:dbCAN_4:DIAMOND-GT:dbCAN_4 -2.773436e-02 -0.21178643
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4 1.730533e-02 -0.13120401
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4 -1.388834e-03 -0.17004469
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4 2.571438e-02 -0.22170864
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4 -1.340793e-01 -0.40660916
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4 -6.054915e-02 -0.34651906
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4 -7.409824e-02 -0.25719446
## GH:CUPP-GT:dbCAN_4 -6.228893e-02 -0.21138314
## GT:CUPP-GT:dbCAN_4 -1.685263e-02 -0.18606974
## PL:CUPP-GT:dbCAN_4 -1.157263e-01 -0.36314932
## CE:CUPP-GT:dbCAN_4 -2.266220e-01 -0.50555731
## AA:CUPP-GT:dbCAN_4 -2.442843e-01 -0.53025417
## CBM:CUPP-GT:dbCAN_4 -8.953454e-01 -1.07939748
## CE:dbCAN_4-PL:dbCAN_4 -1.585263e-01 -0.48570494
## AA:dbCAN_4-PL:dbCAN_4 -8.295629e-02 -0.42141181
## CBM:dbCAN_4-PL:dbCAN_4 -7.598290e-02 -0.33346606
## GH:dbCAN_4:HMMER-PL:dbCAN_4 -1.083677e-02 -0.24487101
## GT:dbCAN_4:HMMER-PL:dbCAN_4 -5.643429e-02 -0.30348377
## PL:dbCAN_4:HMMER-PL:dbCAN_4 1.665335e-15 -0.30658033
## CE:dbCAN_4:HMMER-PL:dbCAN_4 -1.699760e-01 -0.49715463
## AA:dbCAN_4:HMMER-PL:dbCAN_4 -8.881728e-02 -0.42727280
## CBM:dbCAN_4:HMMER-PL:dbCAN_4 -1.182213e-01 -0.37570449
## GH:dbCAN_4:DIAMOND-PL:dbCAN_4 2.983831e-02 -0.20468767
## GT:dbCAN_4:DIAMOND-PL:dbCAN_4 1.498619e-02 -0.23243682
## PL:dbCAN_4:DIAMOND-PL:dbCAN_4 1.180124e-02 -0.29477909
## CE:dbCAN_4:DIAMOND-PL:dbCAN_4 -4.597005e-02 -0.37850311
## AA:dbCAN_4:DIAMOND-PL:dbCAN_4 -6.570735e-02 -0.40416288
## CBM:dbCAN_4:DIAMOND-PL:dbCAN_4 -5.343795e-02 -0.31160169
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4 -8.398265e-03 -0.24255286
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4 -2.709243e-02 -0.27451544
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4 1.078330e-05 -0.30656955
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4 -1.597829e-01 -0.48696155
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4 -8.625274e-02 -0.42470827
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4 -9.980183e-02 -0.35728499
## GH:CUPP-PL:dbCAN_4 -8.799252e-02 -0.32251850
## GT:CUPP-PL:dbCAN_4 -4.255623e-02 -0.29036216
## PL:CUPP-PL:dbCAN_4 -1.414299e-01 -0.44801023
## CE:CUPP-PL:dbCAN_4 -2.523256e-01 -0.58485869
## AA:CUPP-PL:dbCAN_4 -2.699879e-01 -0.60844338
## CBM:CUPP-PL:dbCAN_4 -9.210490e-01 -1.17921274
## AA:dbCAN_4-CE:dbCAN_4 7.556999e-02 -0.28165056
## CBM:dbCAN_4-CE:dbCAN_4 8.254338e-02 -0.19915141
## GH:dbCAN_4:HMMER-CE:dbCAN_4 1.476895e-01 -0.11274552
## GT:dbCAN_4:HMMER-CE:dbCAN_4 1.020920e-01 -0.17009879
## PL:dbCAN_4:HMMER-CE:dbCAN_4 1.585263e-01 -0.16865238
## CE:dbCAN_4:HMMER-CE:dbCAN_4 -1.144970e-02 -0.35800453
## AA:dbCAN_4:HMMER-CE:dbCAN_4 6.970900e-02 -0.28751155
## CBM:dbCAN_4:HMMER-CE:dbCAN_4 4.030495e-02 -0.24138984
## GH:dbCAN_4:DIAMOND-CE:dbCAN_4 1.883646e-01 -0.07251241
## GT:dbCAN_4:DIAMOND-CE:dbCAN_4 1.735125e-01 -0.09901739
## PL:dbCAN_4:DIAMOND-CE:dbCAN_4 1.703275e-01 -0.15685114
## CE:dbCAN_4:DIAMOND-CE:dbCAN_4 1.125562e-01 -0.23905806
## AA:dbCAN_4:DIAMOND-CE:dbCAN_4 9.281892e-02 -0.26440162
## CBM:dbCAN_4:DIAMOND-CE:dbCAN_4 1.050883e-01 -0.17722868
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4 1.501280e-01 -0.11041517
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4 1.314338e-01 -0.14109601
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4 1.585371e-01 -0.16864160
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4 -1.256614e-03 -0.34781145
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4 7.227353e-02 -0.28494701
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4 5.872444e-02 -0.22297034
## GH:CUPP-CE:dbCAN_4 7.053375e-02 -0.19034325
## GT:CUPP-CE:dbCAN_4 1.159700e-01 -0.15690750
## PL:CUPP-CE:dbCAN_4 1.709638e-02 -0.31008228
## CE:CUPP-CE:dbCAN_4 -9.379935e-02 -0.44541365
## AA:CUPP-CE:dbCAN_4 -1.114616e-01 -0.46868212
## CBM:CUPP-CE:dbCAN_4 -7.625227e-01 -1.04483973
## CBM:dbCAN_4-AA:dbCAN_4 6.973389e-03 -0.28774379
## GH:dbCAN_4:HMMER-AA:dbCAN_4 7.211952e-02 -0.20234845
## GT:dbCAN_4:HMMER-AA:dbCAN_4 2.652199e-02 -0.25912479
## PL:dbCAN_4:HMMER-AA:dbCAN_4 8.295629e-02 -0.25549924
## CE:dbCAN_4:HMMER-AA:dbCAN_4 -8.701969e-02 -0.44424023
## AA:dbCAN_4:HMMER-AA:dbCAN_4 -5.860990e-03 -0.37343790
## CBM:dbCAN_4:HMMER-AA:dbCAN_4 -3.526504e-02 -0.32998222
## GH:dbCAN_4:DIAMOND-AA:dbCAN_4 1.127946e-01 -0.16209279
## GT:dbCAN_4:DIAMOND-AA:dbCAN_4 9.794248e-02 -0.18802743
## PL:dbCAN_4:DIAMOND-AA:dbCAN_4 9.475753e-02 -0.24369799
## CE:dbCAN_4:DIAMOND-AA:dbCAN_4 3.698624e-02 -0.32514478
## AA:dbCAN_4:DIAMOND-AA:dbCAN_4 1.724893e-02 -0.35032797
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4 2.951834e-02 -0.26579363
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4 7.455802e-02 -0.20001258
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4 5.586386e-02 -0.23010605
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4 8.296707e-02 -0.25548845
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4 -7.682660e-02 -0.43404715
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4 -3.296457e-03 -0.37087336
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4 -1.684554e-02 -0.31156273
## GH:CUPP-AA:dbCAN_4 -5.036237e-03 -0.27992362
## GT:CUPP-AA:dbCAN_4 4.040006e-02 -0.24590122
## PL:CUPP-AA:dbCAN_4 -5.847361e-02 -0.39692913
## CE:CUPP-AA:dbCAN_4 -1.693693e-01 -0.53150037
## AA:CUPP-AA:dbCAN_4 -1.870316e-01 -0.55460848
## CBM:CUPP-AA:dbCAN_4 -8.380927e-01 -1.13340468
## GH:dbCAN_4:HMMER-CBM:dbCAN_4 6.514613e-02 -0.09940812
## GT:dbCAN_4:HMMER-CBM:dbCAN_4 1.954861e-02 -0.16304252
## PL:dbCAN_4:HMMER-CBM:dbCAN_4 7.598290e-02 -0.18150026
## CE:dbCAN_4:HMMER-CBM:dbCAN_4 -9.399307e-02 -0.37568786
## AA:dbCAN_4:HMMER-CBM:dbCAN_4 -1.283438e-02 -0.30755156
## CBM:dbCAN_4:HMMER-CBM:dbCAN_4 -4.223843e-02 -0.23871655
## GH:dbCAN_4:DIAMOND-CBM:dbCAN_4 1.058212e-01 -0.05943166
## GT:dbCAN_4:DIAMOND-CBM:dbCAN_4 9.096909e-02 -0.09212713
## PL:dbCAN_4:DIAMOND-CBM:dbCAN_4 8.778414e-02 -0.16969902
## CE:dbCAN_4:DIAMOND-CBM:dbCAN_4 3.001285e-02 -0.25788350
## AA:dbCAN_4:DIAMOND-CBM:dbCAN_4 1.027555e-02 -0.28444164
## CBM:dbCAN_4:DIAMOND-CBM:dbCAN_4 2.254495e-02 -0.17482423
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 6.758463e-02 -0.09714075
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 4.889047e-02 -0.13420574
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 7.599368e-02 -0.18148948
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 -8.379999e-02 -0.36549478
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 -1.026985e-02 -0.30498703
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 -2.381893e-02 -0.22029705
## GH:CUPP-CBM:dbCAN_4 -1.200963e-02 -0.17726249
## GT:CUPP-CBM:dbCAN_4 3.342667e-02 -0.15018666
## PL:CUPP-CBM:dbCAN_4 -6.544700e-02 -0.32293015
## CE:CUPP-CBM:dbCAN_4 -1.763427e-01 -0.46423909
## AA:CUPP-CBM:dbCAN_4 -1.940050e-01 -0.48872214
## CBM:CUPP-CBM:dbCAN_4 -8.450661e-01 -1.04243528
## GT:dbCAN_4:HMMER-GH:dbCAN_4:HMMER -4.559752e-02 -0.19329304
## PL:dbCAN_4:HMMER-GH:dbCAN_4:HMMER 1.083677e-02 -0.22319747
## CE:dbCAN_4:HMMER-GH:dbCAN_4:HMMER -1.591392e-01 -0.41957422
## AA:dbCAN_4:HMMER-GH:dbCAN_4:HMMER -7.798051e-02 -0.35244848
## CBM:dbCAN_4:HMMER-GH:dbCAN_4:HMMER -1.073846e-01 -0.27193881
## GH:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 4.067508e-02 -0.08495517
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 2.582296e-02 -0.12249654
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 2.263801e-02 -0.21139623
## CE:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER -3.513328e-02 -0.30226388
## AA:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER -5.487058e-02 -0.32933855
## CBM:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER -4.260118e-02 -0.20821834
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 2.438506e-03 -0.12249708
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER -1.625566e-02 -0.16457515
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 1.084755e-02 -0.22318669
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER -1.489461e-01 -0.40938114
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER -7.541597e-02 -0.34988394
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER -8.896506e-02 -0.25351931
## GH:CUPP-GH:dbCAN_4:HMMER -7.715575e-02 -0.20278600
## GT:CUPP-GH:dbCAN_4:HMMER -3.171946e-02 -0.18067685
## PL:CUPP-GH:dbCAN_4:HMMER -1.305931e-01 -0.36462737
## CE:CUPP-GH:dbCAN_4:HMMER -2.414889e-01 -0.50861947
## AA:CUPP-GH:dbCAN_4:HMMER -2.591511e-01 -0.53361906
## CBM:CUPP-GH:dbCAN_4:HMMER -9.102122e-01 -1.07582939
## PL:dbCAN_4:HMMER-GT:dbCAN_4:HMMER 5.643429e-02 -0.19061518
## CE:dbCAN_4:HMMER-GT:dbCAN_4:HMMER -1.135417e-01 -0.38573245
## AA:dbCAN_4:HMMER-GT:dbCAN_4:HMMER -3.238298e-02 -0.31802976
## CBM:dbCAN_4:HMMER-GT:dbCAN_4:HMMER -6.178703e-02 -0.24437816
## GH:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 8.627260e-02 -0.06220088
## GT:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 7.142048e-02 -0.09668689
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 6.823554e-02 -0.17881394
## CE:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 1.046425e-02 -0.26813973
## AA:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER -9.273060e-03 -0.29491984
## CBM:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 2.996344e-03 -0.18055327
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 4.803603e-02 -0.09985013
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 2.934187e-02 -0.13876551
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 5.644508e-02 -0.19060440
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER -1.033486e-01 -0.37553937
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER -2.981845e-02 -0.31546523
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER -4.336754e-02 -0.22595866
## GH:CUPP-GT:dbCAN_4:HMMER -3.155823e-02 -0.18003171
## GT:CUPP-GT:dbCAN_4:HMMER 1.387807e-02 -0.15479239
## PL:CUPP-GT:dbCAN_4:HMMER -8.499560e-02 -0.33204507
## CE:CUPP-GT:dbCAN_4:HMMER -1.958913e-01 -0.47449532
## AA:CUPP-GT:dbCAN_4:HMMER -2.135536e-01 -0.49920034
## CBM:CUPP-GT:dbCAN_4:HMMER -8.646147e-01 -1.04816432
## CE:dbCAN_4:HMMER-PL:dbCAN_4:HMMER -1.699760e-01 -0.49715463
## AA:dbCAN_4:HMMER-PL:dbCAN_4:HMMER -8.881728e-02 -0.42727280
## CBM:dbCAN_4:HMMER-PL:dbCAN_4:HMMER -1.182213e-01 -0.37570449
## GH:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 2.983831e-02 -0.20468767
## GT:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 1.498619e-02 -0.23243682
## PL:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 1.180124e-02 -0.29477909
## CE:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER -4.597005e-02 -0.37850311
## AA:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER -6.570735e-02 -0.40416288
## CBM:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER -5.343795e-02 -0.31160169
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER -8.398265e-03 -0.24255286
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER -2.709243e-02 -0.27451544
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 1.078330e-05 -0.30656955
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER -1.597829e-01 -0.48696155
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER -8.625274e-02 -0.42470827
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER -9.980183e-02 -0.35728499
## GH:CUPP-PL:dbCAN_4:HMMER -8.799252e-02 -0.32251850
## GT:CUPP-PL:dbCAN_4:HMMER -4.255623e-02 -0.29036216
## PL:CUPP-PL:dbCAN_4:HMMER -1.414299e-01 -0.44801023
## CE:CUPP-PL:dbCAN_4:HMMER -2.523256e-01 -0.58485869
## AA:CUPP-PL:dbCAN_4:HMMER -2.699879e-01 -0.60844338
## CBM:CUPP-PL:dbCAN_4:HMMER -9.210490e-01 -1.17921274
## AA:dbCAN_4:HMMER-CE:dbCAN_4:HMMER 8.115870e-02 -0.27606185
## CBM:dbCAN_4:HMMER-CE:dbCAN_4:HMMER 5.175465e-02 -0.22994014
## GH:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 1.998143e-01 -0.06106272
## GT:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 1.849622e-01 -0.08756769
## PL:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 1.817772e-01 -0.14540145
## CE:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 1.240059e-01 -0.22760837
## AA:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 1.042686e-01 -0.25295192
## CBM:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 1.165380e-01 -0.16577899
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 1.615777e-01 -0.09896548
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 1.428835e-01 -0.12964631
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 1.699868e-01 -0.15719190
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 1.019308e-02 -0.33636175
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 8.372323e-02 -0.27349732
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 7.017414e-02 -0.21152064
## GH:CUPP-CE:dbCAN_4:HMMER 8.198345e-02 -0.17889355
## GT:CUPP-CE:dbCAN_4:HMMER 1.274197e-01 -0.14545780
## PL:CUPP-CE:dbCAN_4:HMMER 2.854608e-02 -0.29863258
## CE:CUPP-CE:dbCAN_4:HMMER -8.234966e-02 -0.43396395
## AA:CUPP-CE:dbCAN_4:HMMER -1.000119e-01 -0.45723243
## CBM:CUPP-CE:dbCAN_4:HMMER -7.510730e-01 -1.03339004
## CBM:dbCAN_4:HMMER-AA:dbCAN_4:HMMER -2.940405e-02 -0.32412123
## GH:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 1.186556e-01 -0.15623180
## GT:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 1.038035e-01 -0.18216644
## PL:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 1.006185e-01 -0.23783700
## CE:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 4.284723e-02 -0.31928379
## AA:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 2.310992e-02 -0.34446698
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 3.537933e-02 -0.25993264
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 8.041901e-02 -0.19415159
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 6.172485e-02 -0.22424506
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 8.882806e-02 -0.24962746
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER -7.096561e-02 -0.42818616
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 2.564533e-03 -0.36501237
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER -1.098455e-02 -0.30570174
## GH:CUPP-AA:dbCAN_4:HMMER 8.247535e-04 -0.27406263
## GT:CUPP-AA:dbCAN_4:HMMER 4.626105e-02 -0.24004023
## PL:CUPP-AA:dbCAN_4:HMMER -5.261262e-02 -0.39106814
## CE:CUPP-AA:dbCAN_4:HMMER -1.635084e-01 -0.52563937
## AA:CUPP-AA:dbCAN_4:HMMER -1.811706e-01 -0.54874749
## CBM:CUPP-AA:dbCAN_4:HMMER -8.322317e-01 -1.12754369
## GH:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 1.480596e-01 -0.01719323
## GT:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 1.332075e-01 -0.04988870
## PL:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 1.300226e-01 -0.12746059
## CE:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 7.225128e-02 -0.21564508
## AA:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 5.251397e-02 -0.24220321
## CBM:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 6.478338e-02 -0.13258581
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 1.098231e-01 -0.05490232
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 9.112890e-02 -0.09196732
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 1.182321e-01 -0.13925105
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER -4.156156e-02 -0.32325635
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 3.196858e-02 -0.26274860
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 1.841950e-02 -0.17805863
## GH:CUPP-CBM:dbCAN_4:HMMER 3.022880e-02 -0.13502406
## GT:CUPP-CBM:dbCAN_4:HMMER 7.566510e-02 -0.10794823
## PL:CUPP-CBM:dbCAN_4:HMMER -2.320857e-02 -0.28069173
## CE:CUPP-CBM:dbCAN_4:HMMER -1.341043e-01 -0.42200066
## AA:CUPP-CBM:dbCAN_4:HMMER -1.517665e-01 -0.44648371
## CBM:CUPP-CBM:dbCAN_4:HMMER -8.028277e-01 -1.00019686
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND -1.485212e-02 -0.16394632
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND -1.803707e-02 -0.25256304
## CE:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND -7.580836e-02 -0.34336988
## AA:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND -9.554566e-02 -0.37043305
## CBM:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND -8.327626e-02 -0.24958757
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND -3.823657e-02 -0.16409089
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND -5.693074e-02 -0.20602494
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND -2.982753e-02 -0.26435350
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND -1.896212e-01 -0.45049820
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND -1.160911e-01 -0.39097844
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND -1.296401e-01 -0.29489301
## GH:CUPP-GH:dbCAN_4:DIAMOND -1.178308e-01 -0.24437477
## GT:CUPP-GH:dbCAN_4:DIAMOND -7.239454e-02 -0.22212334
## PL:CUPP-GH:dbCAN_4:DIAMOND -1.712682e-01 -0.40579418
## CE:CUPP-GH:dbCAN_4:DIAMOND -2.821639e-01 -0.54972547
## AA:CUPP-GH:dbCAN_4:DIAMOND -2.998262e-01 -0.57471355
## CBM:CUPP-GH:dbCAN_4:DIAMOND -9.508873e-01 -1.11719862
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4:DIAMOND -3.184948e-03 -0.25060796
## CE:dbCAN_4:DIAMOND-GT:dbCAN_4:DIAMOND -6.095624e-02 -0.33989151
## AA:dbCAN_4:DIAMOND-GT:dbCAN_4:DIAMOND -8.069354e-02 -0.36666345
## CBM:dbCAN_4:DIAMOND-GT:dbCAN_4:DIAMOND -6.842414e-02 -0.25247622
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND -2.338446e-02 -0.17189379
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND -4.207862e-02 -0.21073447
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND -1.497541e-02 -0.26239842
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND -1.747691e-01 -0.44729894
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND -1.012389e-01 -0.38720885
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND -1.147880e-01 -0.29788424
## GH:CUPP-GT:dbCAN_4:DIAMOND -1.029787e-01 -0.25207292
## GT:CUPP-GT:dbCAN_4:DIAMOND -5.754242e-02 -0.22675952
## PL:CUPP-GT:dbCAN_4:DIAMOND -1.564161e-01 -0.40383910
## CE:CUPP-GT:dbCAN_4:DIAMOND -2.673118e-01 -0.54624709
## AA:CUPP-GT:dbCAN_4:DIAMOND -2.849740e-01 -0.57094396
## CBM:CUPP-GT:dbCAN_4:DIAMOND -9.360352e-01 -1.12008727
## CE:dbCAN_4:DIAMOND-PL:dbCAN_4:DIAMOND -5.777129e-02 -0.39030435
## AA:dbCAN_4:DIAMOND-PL:dbCAN_4:DIAMOND -7.750860e-02 -0.41596412
## CBM:dbCAN_4:DIAMOND-PL:dbCAN_4:DIAMOND -6.523919e-02 -0.32340294
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -2.019951e-02 -0.25435410
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -3.889367e-02 -0.28631668
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -1.179046e-02 -0.31837079
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -1.715841e-01 -0.49876279
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -9.805399e-02 -0.43650951
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -1.116031e-01 -0.36908623
## GH:CUPP-PL:dbCAN_4:DIAMOND -9.979377e-02 -0.33431974
## GT:CUPP-PL:dbCAN_4:DIAMOND -5.435747e-02 -0.30216340
## PL:CUPP-PL:dbCAN_4:DIAMOND -1.532311e-01 -0.45981147
## CE:CUPP-PL:dbCAN_4:DIAMOND -2.641269e-01 -0.59665993
## AA:CUPP-PL:dbCAN_4:DIAMOND -2.817891e-01 -0.62024462
## CBM:CUPP-PL:dbCAN_4:DIAMOND -9.328502e-01 -1.19101399
## AA:dbCAN_4:DIAMOND-CE:dbCAN_4:DIAMOND -1.973731e-02 -0.38186833
## CBM:dbCAN_4:DIAMOND-CE:dbCAN_4:DIAMOND -7.467902e-03 -0.29597311
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 3.757178e-02 -0.22966428
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 1.887762e-02 -0.26005765
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 4.598083e-02 -0.28655223
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND -1.138128e-01 -0.46542714
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND -4.028270e-02 -0.40241372
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND -5.383178e-02 -0.34172814
## GH:CUPP-CE:dbCAN_4:DIAMOND -4.202248e-02 -0.30958400
## GT:CUPP-CE:dbCAN_4:DIAMOND 3.413820e-03 -0.27586116
## PL:CUPP-CE:dbCAN_4:DIAMOND -9.545985e-02 -0.42799291
## CE:CUPP-CE:dbCAN_4:DIAMOND -2.063556e-01 -0.56295756
## AA:CUPP-CE:dbCAN_4:DIAMOND -2.240178e-01 -0.58614883
## CBM:CUPP-CE:dbCAN_4:DIAMOND -8.750790e-01 -1.16358416
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND 1.226940e-02 -0.28304257
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 5.730909e-02 -0.21726151
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 3.861493e-02 -0.24735498
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 6.571814e-02 -0.27273739
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND -9.407554e-02 -0.45129608
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND -2.054539e-02 -0.38812230
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND -3.409448e-02 -0.32881166
## GH:CUPP-AA:dbCAN_4:DIAMOND -2.228517e-02 -0.29717256
## GT:CUPP-AA:dbCAN_4:DIAMOND 2.315113e-02 -0.26315015
## PL:CUPP-AA:dbCAN_4:DIAMOND -7.572254e-02 -0.41417807
## CE:CUPP-AA:dbCAN_4:DIAMOND -1.866183e-01 -0.54874930
## AA:CUPP-AA:dbCAN_4:DIAMOND -2.042805e-01 -0.57185741
## CBM:CUPP-AA:dbCAN_4:DIAMOND -8.553416e-01 -1.15065362
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 4.503968e-02 -0.12074751
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 2.634552e-02 -0.15770655
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 5.344873e-02 -0.20471501
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND -1.063449e-01 -0.38866195
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND -3.281480e-02 -0.32812677
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND -4.636388e-02 -0.24373307
## GH:CUPP-CBM:dbCAN_4:DIAMOND -3.455458e-02 -0.20086588
## GT:CUPP-CBM:dbCAN_4:DIAMOND 1.088172e-02 -0.17368479
## PL:CUPP-CBM:dbCAN_4:DIAMOND -8.799195e-02 -0.34615569
## CE:CUPP-CBM:dbCAN_4:DIAMOND -1.988877e-01 -0.48739289
## AA:CUPP-CBM:dbCAN_4:DIAMOND -2.165499e-01 -0.51186188
## CBM:CUPP-CBM:dbCAN_4:DIAMOND -8.676110e-01 -1.06586729
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub -1.869416e-02 -0.16720350
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub 8.409048e-03 -0.22574555
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub -1.513846e-01 -0.41192781
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub -7.785448e-02 -0.35242508
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub -9.140357e-02 -0.25612895
## GH:CUPP-GH:dbCAN_4:dbCAN-sub -7.959426e-02 -0.20544857
## GT:CUPP-GH:dbCAN_4:dbCAN-sub -3.415796e-02 -0.18330438
## PL:CUPP-GH:dbCAN_4:dbCAN-sub -1.330316e-01 -0.36718623
## CE:CUPP-GH:dbCAN_4:dbCAN-sub -2.439274e-01 -0.51116342
## AA:CUPP-GH:dbCAN_4:dbCAN-sub -2.615896e-01 -0.53616020
## CBM:CUPP-GH:dbCAN_4:dbCAN-sub -9.126507e-01 -1.07843793
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:dbCAN-sub 2.710321e-02 -0.22031981
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4:dbCAN-sub -1.326905e-01 -0.40522032
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4:dbCAN-sub -5.916032e-02 -0.34513023
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4:dbCAN-sub -7.270941e-02 -0.25580562
## GH:CUPP-GT:dbCAN_4:dbCAN-sub -6.090010e-02 -0.20999430
## GT:CUPP-GT:dbCAN_4:dbCAN-sub -1.546380e-02 -0.18468090
## PL:CUPP-GT:dbCAN_4:dbCAN-sub -1.143375e-01 -0.36176048
## CE:CUPP-GT:dbCAN_4:dbCAN-sub -2.252332e-01 -0.50416847
## AA:CUPP-GT:dbCAN_4:dbCAN-sub -2.428954e-01 -0.52886534
## CBM:CUPP-GT:dbCAN_4:dbCAN-sub -8.939566e-01 -1.07800865
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4:dbCAN-sub -1.597937e-01 -0.48697233
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4:dbCAN-sub -8.626353e-02 -0.42471905
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4:dbCAN-sub -9.981262e-02 -0.35729577
## GH:CUPP-PL:dbCAN_4:dbCAN-sub -8.800331e-02 -0.32252928
## GT:CUPP-PL:dbCAN_4:dbCAN-sub -4.256701e-02 -0.29037294
## PL:CUPP-PL:dbCAN_4:dbCAN-sub -1.414407e-01 -0.44802101
## CE:CUPP-PL:dbCAN_4:dbCAN-sub -2.523364e-01 -0.58486947
## AA:CUPP-PL:dbCAN_4:dbCAN-sub -2.699986e-01 -0.60845416
## CBM:CUPP-PL:dbCAN_4:dbCAN-sub -9.210598e-01 -1.17922353
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4:dbCAN-sub 7.353015e-02 -0.28369040
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4:dbCAN-sub 5.998106e-02 -0.22171373
## GH:CUPP-CE:dbCAN_4:dbCAN-sub 7.179037e-02 -0.18908663
## GT:CUPP-CE:dbCAN_4:dbCAN-sub 1.172267e-01 -0.15565088
## PL:CUPP-CE:dbCAN_4:dbCAN-sub 1.835299e-02 -0.30882567
## CE:CUPP-CE:dbCAN_4:dbCAN-sub -9.254274e-02 -0.44415703
## AA:CUPP-CE:dbCAN_4:dbCAN-sub -1.102050e-01 -0.46742551
## CBM:CUPP-CE:dbCAN_4:dbCAN-sub -7.612661e-01 -1.04358312
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub -1.354909e-02 -0.30826627
## GH:CUPP-AA:dbCAN_4:dbCAN-sub -1.739780e-03 -0.27662717
## GT:CUPP-AA:dbCAN_4:dbCAN-sub 4.369652e-02 -0.24260476
## PL:CUPP-AA:dbCAN_4:dbCAN-sub -5.517715e-02 -0.39363267
## CE:CUPP-AA:dbCAN_4:dbCAN-sub -1.660729e-01 -0.52820391
## AA:CUPP-AA:dbCAN_4:dbCAN-sub -1.837351e-01 -0.55131202
## CBM:CUPP-AA:dbCAN_4:dbCAN-sub -8.347963e-01 -1.13010822
## GH:CUPP-CBM:dbCAN_4:dbCAN-sub 1.180931e-02 -0.15344356
## GT:CUPP-CBM:dbCAN_4:dbCAN-sub 5.724560e-02 -0.12636773
## PL:CUPP-CBM:dbCAN_4:dbCAN-sub -4.162806e-02 -0.29911122
## CE:CUPP-CBM:dbCAN_4:dbCAN-sub -1.525238e-01 -0.44042016
## AA:CUPP-CBM:dbCAN_4:dbCAN-sub -1.701860e-01 -0.46490321
## CBM:CUPP-CBM:dbCAN_4:dbCAN-sub -8.212472e-01 -1.01861635
## GT:CUPP-GH:CUPP 4.543630e-02 -0.10429250
## PL:CUPP-GH:CUPP -5.343737e-02 -0.28796335
## CE:CUPP-GH:CUPP -1.643331e-01 -0.43189463
## AA:CUPP-GH:CUPP -1.819953e-01 -0.45688272
## CBM:CUPP-GH:CUPP -8.330565e-01 -0.99936778
## PL:CUPP-GT:CUPP -9.887367e-02 -0.34667960
## CE:CUPP-GT:CUPP -2.097694e-01 -0.48904439
## AA:CUPP-GT:CUPP -2.274316e-01 -0.51373291
## CBM:CUPP-GT:CUPP -8.784928e-01 -1.06305929
## CE:CUPP-PL:CUPP -1.108957e-01 -0.44342880
## AA:CUPP-PL:CUPP -1.285580e-01 -0.46701349
## CBM:CUPP-PL:CUPP -7.796191e-01 -1.03778285
## AA:CUPP-CE:CUPP -1.766223e-02 -0.37979325
## CBM:CUPP-CE:CUPP -6.687234e-01 -0.95722858
## CBM:CUPP-AA:CUPP -6.510611e-01 -0.94637311
## upr p adj
## GT:dbCAN_4-GH:dbCAN_4 0.1195479151 1.0000000
## PL:dbCAN_4-GH:dbCAN_4 0.2308264555 1.0000000
## CE:dbCAN_4-GH:dbCAN_4 0.0986764096 0.8782314
## AA:dbCAN_4-GH:dbCAN_4 0.1882682158 0.9999985
## CBM:dbCAN_4-GH:dbCAN_4 0.0854657365 0.9948612
## GH:dbCAN_4:HMMER-GH:dbCAN_4 0.1108772197 1.0000000
## GT:dbCAN_4:HMMER-GH:dbCAN_4 0.0881948473 0.9997395
## PL:dbCAN_4:HMMER-GH:dbCAN_4 0.2308264555 1.0000000
## CE:dbCAN_4:HMMER-GH:dbCAN_4 0.0872267124 0.7811955
## AA:dbCAN_4:HMMER-GH:dbCAN_4 0.1824072253 0.9999938
## CBM:dbCAN_4:HMMER-GH:dbCAN_4 0.0432273081 0.5699641
## GH:dbCAN_4:DIAMOND-GH:dbCAN_4 0.1524693644 1.0000000
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4 0.1602376981 1.0000000
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4 0.2426276977 1.0000000
## CE:dbCAN_4:DIAMOND-GH:dbCAN_4 0.2179227670 1.0000000
## AA:dbCAN_4:DIAMOND-GH:dbCAN_4 0.2055171495 1.0000000
## CBM:dbCAN_4:DIAMOND-GH:dbCAN_4 0.1090713884 0.9999905
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4 0.1135406272 1.0000000
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4 0.1181590807 1.0000000
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4 0.2308372388 1.0000000
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4 0.0974197959 0.8691409
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4 0.1849717588 0.9999966
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4 0.0616468037 0.8693205
## GH:CUPP-GH:dbCAN_4 0.0346385298 0.6090402
## GT:CUPP-GH:dbCAN_4 0.1033315445 0.9999991
## PL:CUPP-GH:dbCAN_4 0.0893965600 0.8837060
## CE:CUPP-GH:dbCAN_4 0.0115671835 0.0846933
## AA:CUPP-GH:dbCAN_4 0.0012366468 0.0529249
## CBM:CUPP-GH:dbCAN_4 -0.7585396613 0.0000000
## PL:dbCAN_4-GT:dbCAN_4 0.2731266079 1.0000000
## CE:dbCAN_4-GT:dbCAN_4 0.1397071748 0.9938637
## AA:dbCAN_4-GT:dbCAN_4 0.2287172147 1.0000000
## CBM:dbCAN_4-GT:dbCAN_4 0.1328169091 0.9999999
## GH:dbCAN_4:HMMER-GT:dbCAN_4 0.1631863194 1.0000000
## GT:dbCAN_4:HMMER-GT:dbCAN_4 0.1373766743 1.0000000
## PL:dbCAN_4:HMMER-GT:dbCAN_4 0.2731266079 1.0000000
## CE:dbCAN_4:HMMER-GT:dbCAN_4 0.1282574775 0.9802241
## AA:dbCAN_4:HMMER-GT:dbCAN_4 0.2228562242 1.0000000
## CBM:dbCAN_4:HMMER-GT:dbCAN_4 0.0905784807 0.9895767
## GH:dbCAN_4:DIAMOND-GT:dbCAN_4 0.2046361060 0.9999469
## GT:dbCAN_4:DIAMOND-GT:dbCAN_4 0.2093456348 1.0000000
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4 0.2849278501 1.0000000
## CE:dbCAN_4:DIAMOND-GT:dbCAN_4 0.2586688138 1.0000000
## AA:dbCAN_4:DIAMOND-GT:dbCAN_4 0.2459661484 1.0000000
## CBM:dbCAN_4:DIAMOND-GT:dbCAN_4 0.1563177183 1.0000000
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4 0.1658146649 1.0000000
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4 0.1672670174 1.0000000
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4 0.2731373912 1.0000000
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4 0.1384505610 0.9929357
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4 0.2254207577 1.0000000
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4 0.1089979763 0.9997360
## GH:CUPP-GT:dbCAN_4 0.0868052714 0.9995261
## GT:CUPP-GT:dbCAN_4 0.1523644692 1.0000000
## PL:CUPP-GT:dbCAN_4 0.1316967124 0.9967557
## CE:CUPP-GT:dbCAN_4 0.0523132303 0.3477489
## AA:CUPP-GT:dbCAN_4 0.0416856458 0.2450326
## CBM:CUPP-GT:dbCAN_4 -0.7112933314 0.0000000
## CE:dbCAN_4-PL:dbCAN_4 0.1686523847 0.9943835
## AA:dbCAN_4-PL:dbCAN_4 0.2554992364 1.0000000
## CBM:dbCAN_4-PL:dbCAN_4 0.1815002588 0.9999997
## GH:dbCAN_4:HMMER-PL:dbCAN_4 0.2231974698 1.0000000
## GT:dbCAN_4:HMMER-PL:dbCAN_4 0.1906151791 1.0000000
## PL:dbCAN_4:HMMER-PL:dbCAN_4 0.3065803336 1.0000000
## CE:dbCAN_4:HMMER-PL:dbCAN_4 0.1572026875 0.9846406
## AA:dbCAN_4:HMMER-PL:dbCAN_4 0.2496382459 1.0000000
## CBM:dbCAN_4:HMMER-PL:dbCAN_4 0.1392618304 0.9975928
## GH:dbCAN_4:DIAMOND-PL:dbCAN_4 0.2643642869 1.0000000
## GT:dbCAN_4:DIAMOND-PL:dbCAN_4 0.2624092063 1.0000000
## PL:dbCAN_4:DIAMOND-PL:dbCAN_4 0.3183815758 1.0000000
## CE:dbCAN_4:DIAMOND-PL:dbCAN_4 0.2865630134 1.0000000
## AA:dbCAN_4:DIAMOND-PL:dbCAN_4 0.2727481701 1.0000000
## CBM:dbCAN_4:DIAMOND-PL:dbCAN_4 0.2047257946 1.0000000
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4 0.2257563328 1.0000000
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4 0.2203305889 1.0000000
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4 0.3065911169 1.0000000
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4 0.1673957710 0.9936723
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4 0.2522027794 1.0000000
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4 0.1576813260 0.9998839
## GH:CUPP-PL:dbCAN_4 0.1465334523 0.9999388
## GT:CUPP-PL:dbCAN_4 0.2052497062 1.0000000
## PL:CUPP-PL:dbCAN_4 0.1651504381 0.9974009
## CE:CUPP-PL:dbCAN_4 0.0802074299 0.5048537
## AA:CUPP-PL:dbCAN_4 0.0684676674 0.3886688
## CBM:CUPP-PL:dbCAN_4 -0.6628852551 0.0000000
## AA:dbCAN_4-CE:dbCAN_4 0.4327905321 1.0000000
## CBM:dbCAN_4-CE:dbCAN_4 0.3642381617 0.9999997
## GH:dbCAN_4:HMMER-CE:dbCAN_4 0.4081245277 0.9534939
## GT:dbCAN_4:HMMER-CE:dbCAN_4 0.3742827558 0.9999391
## PL:dbCAN_4:HMMER-CE:dbCAN_4 0.4857049368 0.9943835
## CE:dbCAN_4:HMMER-CE:dbCAN_4 0.3351051342 1.0000000
## AA:dbCAN_4:HMMER-CE:dbCAN_4 0.4269295417 1.0000000
## CBM:dbCAN_4:HMMER-CE:dbCAN_4 0.3219997333 1.0000000
## GH:dbCAN_4:DIAMOND-CE:dbCAN_4 0.4492415858 0.6189818
## GT:dbCAN_4:DIAMOND-CE:dbCAN_4 0.4460423252 0.8481215
## PL:dbCAN_4:DIAMOND-CE:dbCAN_4 0.4975061791 0.9842019
## CE:dbCAN_4:DIAMOND-CE:dbCAN_4 0.4641705225 0.9999978
## AA:dbCAN_4:DIAMOND-CE:dbCAN_4 0.4500394659 1.0000000
## CBM:dbCAN_4:DIAMOND-CE:dbCAN_4 0.3874053362 0.9999477
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4 0.4106711953 0.9441871
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4 0.4039637078 0.9947682
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4 0.4857157201 0.9943777
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4 0.3452982177 1.0000000
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4 0.4294940751 1.0000000
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4 0.3404192288 1.0000000
## GH:CUPP-CE:dbCAN_4 0.3314107512 1.0000000
## GT:CUPP-CE:dbCAN_4 0.3888475961 0.9993558
## PL:CUPP-CE:dbCAN_4 0.3442750414 1.0000000
## CE:CUPP-CE:dbCAN_4 0.2578149391 1.0000000
## AA:CUPP-CE:dbCAN_4 0.2457589632 0.9999988
## CBM:CUPP-CE:dbCAN_4 -0.4802057135 0.0000000
## CBM:dbCAN_4-AA:dbCAN_4 0.3016905707 1.0000000
## GH:dbCAN_4:HMMER-AA:dbCAN_4 0.3465874870 1.0000000
## GT:dbCAN_4:HMMER-AA:dbCAN_4 0.3121687738 1.0000000
## PL:dbCAN_4:HMMER-AA:dbCAN_4 0.4214118118 1.0000000
## CE:dbCAN_4:HMMER-AA:dbCAN_4 0.2702008582 1.0000000
## AA:dbCAN_4:HMMER-AA:dbCAN_4 0.3617159166 1.0000000
## CBM:dbCAN_4:HMMER-AA:dbCAN_4 0.2594521423 1.0000000
## GH:dbCAN_4:DIAMOND-AA:dbCAN_4 0.3876819831 0.9996589
## GT:dbCAN_4:DIAMOND-AA:dbCAN_4 0.3839123885 0.9999906
## PL:dbCAN_4:DIAMOND-AA:dbCAN_4 0.4332130540 0.9999999
## CE:dbCAN_4:DIAMOND-AA:dbCAN_4 0.3991172627 1.0000000
## AA:dbCAN_4:DIAMOND-AA:dbCAN_4 0.3848258408 1.0000000
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4 0.3248303082 1.0000000
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4 0.3491286266 1.0000000
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4 0.3418337711 1.0000000
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4 0.4214225951 1.0000000
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4 0.2803939417 1.0000000
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4 0.3642804501 1.0000000
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4 0.2778716379 1.0000000
## GH:CUPP-AA:dbCAN_4 0.2698511485 1.0000000
## GT:CUPP-AA:dbCAN_4 0.3267013379 1.0000000
## PL:CUPP-AA:dbCAN_4 0.2799819163 1.0000000
## CE:CUPP-AA:dbCAN_4 0.1927616792 0.9967585
## AA:CUPP-AA:dbCAN_4 0.1805453381 0.9884949
## CBM:CUPP-AA:dbCAN_4 -0.5427807415 0.0000000
## GH:dbCAN_4:HMMER-CBM:dbCAN_4 0.2297003788 0.9998256
## GT:dbCAN_4:HMMER-CBM:dbCAN_4 0.2021397269 1.0000000
## PL:dbCAN_4:HMMER-CBM:dbCAN_4 0.3334660568 0.9999997
## CE:dbCAN_4:HMMER-CBM:dbCAN_4 0.1877017103 0.9999946
## AA:dbCAN_4:HMMER-CBM:dbCAN_4 0.2818828029 1.0000000
## CBM:dbCAN_4:HMMER-CBM:dbCAN_4 0.1542396930 1.0000000
## GH:dbCAN_4:DIAMOND-CBM:dbCAN_4 0.2710740743 0.8402522
## GT:dbCAN_4:DIAMOND-CBM:dbCAN_4 0.2740653056 0.9918341
## PL:dbCAN_4:DIAMOND-CBM:dbCAN_4 0.3452672991 0.9999915
## CE:dbCAN_4:DIAMOND-CBM:dbCAN_4 0.3179092082 1.0000000
## AA:dbCAN_4:DIAMOND-CBM:dbCAN_4 0.3049927271 1.0000000
## CBM:dbCAN_4:DIAMOND-CBM:dbCAN_4 0.2199141326 1.0000000
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 0.2323100154 0.9996595
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 0.2319866882 1.0000000
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 0.3334768401 0.9999997
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 0.1978947938 0.9999996
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 0.2844473364 1.0000000
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 0.1726591885 1.0000000
## GH:CUPP-CBM:dbCAN_4 0.1532432397 1.0000000
## GT:CUPP-CBM:dbCAN_4 0.2170400053 1.0000000
## PL:CUPP-CBM:dbCAN_4 0.1920361614 1.0000000
## CE:CUPP-CBM:dbCAN_4 0.1115536247 0.8939650
## AA:CUPP-CBM:dbCAN_4 0.1007122244 0.7988849
## CBM:CUPP-CBM:dbCAN_4 -0.6476969171 0.0000000
## GT:dbCAN_4:HMMER-GH:dbCAN_4:HMMER 0.1020979978 0.9999990
## PL:dbCAN_4:HMMER-GH:dbCAN_4:HMMER 0.2448710112 1.0000000
## CE:dbCAN_4:HMMER-GH:dbCAN_4:HMMER 0.1012958197 0.8964306
## AA:dbCAN_4:HMMER-GH:dbCAN_4:HMMER 0.1964874625 0.9999999
## CBM:dbCAN_4:HMMER-GH:dbCAN_4:HMMER 0.0571696937 0.8125835
## GH:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 0.1663053265 0.9999972
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 0.1741424592 1.0000000
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 0.2566722534 1.0000000
## CE:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 0.2319973305 1.0000000
## AA:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 0.2195973867 1.0000000
## CBM:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 0.1230159809 1.0000000
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 0.1273740907 1.0000000
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 0.1320638418 1.0000000
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 0.2448817945 1.0000000
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 0.1114889032 0.9487265
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 0.1990519960 0.9999999
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 0.0755891893 0.9740084
## GH:CUPP-GH:dbCAN_4:HMMER 0.0484744919 0.8911911
## GT:CUPP-GH:dbCAN_4:HMMER 0.1172379381 1.0000000
## PL:CUPP-GH:dbCAN_4:HMMER 0.1034411157 0.9615655
## CE:CUPP-GH:dbCAN_4:HMMER 0.0256417470 0.1513937
## AA:CUPP-GH:dbCAN_4:HMMER 0.0153168841 0.0978531
## CBM:CUPP-GH:dbCAN_4:HMMER -0.7445950688 0.0000000
## PL:dbCAN_4:HMMER-GT:dbCAN_4:HMMER 0.3034837671 1.0000000
## CE:dbCAN_4:HMMER-GT:dbCAN_4:HMMER 0.1586490944 0.9995391
## AA:dbCAN_4:HMMER-GT:dbCAN_4:HMMER 0.2532637959 1.0000000
## CBM:dbCAN_4:HMMER-GT:dbCAN_4:HMMER 0.1208040885 0.9999928
## GH:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 0.2347460868 0.9387228
## GT:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 0.2395278607 0.9993596
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 0.3152850094 0.9999999
## CE:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 0.2890682267 1.0000000
## AA:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 0.2763737202 1.0000000
## CBM:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 0.1865459564 1.0000000
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 0.1959221908 0.9999970
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 0.1974492433 1.0000000
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 0.3034945504 1.0000000
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 0.1688421779 0.9999224
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 0.2558283294 1.0000000
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 0.1392235840 1.0000000
## GH:CUPP-GT:dbCAN_4:HMMER 0.1169152522 1.0000000
## GT:CUPP-GT:dbCAN_4:HMMER 0.1825485202 1.0000000
## PL:CUPP-GT:dbCAN_4:HMMER 0.1620538717 0.9999897
## CE:CUPP-GT:dbCAN_4:HMMER 0.0827126432 0.6762846
## AA:CUPP-GT:dbCAN_4:HMMER 0.0720932175 0.5395616
## CBM:CUPP-GT:dbCAN_4:HMMER -0.6810650933 0.0000000
## CE:dbCAN_4:HMMER-PL:dbCAN_4:HMMER 0.1572026875 0.9846406
## AA:dbCAN_4:HMMER-PL:dbCAN_4:HMMER 0.2496382459 1.0000000
## CBM:dbCAN_4:HMMER-PL:dbCAN_4:HMMER 0.1392618304 0.9975928
## GH:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 0.2643642869 1.0000000
## GT:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 0.2624092063 1.0000000
## PL:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 0.3183815758 1.0000000
## CE:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 0.2865630134 1.0000000
## AA:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 0.2727481701 1.0000000
## CBM:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 0.2047257946 1.0000000
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 0.2257563328 1.0000000
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 0.2203305889 1.0000000
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 0.3065911169 1.0000000
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 0.1673957710 0.9936723
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 0.2522027794 1.0000000
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 0.1576813260 0.9998839
## GH:CUPP-PL:dbCAN_4:HMMER 0.1465334523 0.9999388
## GT:CUPP-PL:dbCAN_4:HMMER 0.2052497062 1.0000000
## PL:CUPP-PL:dbCAN_4:HMMER 0.1651504381 0.9974009
## CE:CUPP-PL:dbCAN_4:HMMER 0.0802074299 0.5048537
## AA:CUPP-PL:dbCAN_4:HMMER 0.0684676674 0.3886688
## CBM:CUPP-PL:dbCAN_4:HMMER -0.6628852551 0.0000000
## AA:dbCAN_4:HMMER-CE:dbCAN_4:HMMER 0.4383792389 1.0000000
## CBM:dbCAN_4:HMMER-CE:dbCAN_4:HMMER 0.3334494305 1.0000000
## GH:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 0.4606912830 0.4829042
## GT:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 0.4574920225 0.7460112
## PL:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 0.5089558763 0.9635260
## CE:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 0.4756202198 0.9999827
## AA:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 0.4614891631 0.9999997
## CBM:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 0.3988550334 0.9996192
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 0.4221208925 0.8805573
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 0.4154134051 0.9826176
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 0.4971654174 0.9846273
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 0.3567479149 1.0000000
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 0.4409437724 1.0000000
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 0.3518689261 1.0000000
## GH:CUPP-CE:dbCAN_4:HMMER 0.3428604484 0.9999986
## GT:CUPP-CE:dbCAN_4:HMMER 0.4002972933 0.9968407
## PL:CUPP-CE:dbCAN_4:HMMER 0.3557247386 1.0000000
## CE:CUPP-CE:dbCAN_4:HMMER 0.2692646363 1.0000000
## AA:CUPP-CE:dbCAN_4:HMMER 0.2572086605 0.9999999
## CBM:CUPP-CE:dbCAN_4:HMMER -0.4687560163 0.0000000
## CBM:dbCAN_4:HMMER-AA:dbCAN_4:HMMER 0.2653131328 1.0000000
## GH:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 0.3935429736 0.9991524
## GT:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 0.3897733789 0.9999686
## PL:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 0.4390740445 0.9999996
## CE:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 0.4049782532 1.0000000
## AA:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 0.3906868313 1.0000000
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 0.3306912987 1.0000000
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 0.3549896171 0.9999997
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 0.3476947615 1.0000000
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 0.4272835855 1.0000000
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 0.2862549321 1.0000000
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 0.3701414405 1.0000000
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 0.2837326284 1.0000000
## GH:CUPP-AA:dbCAN_4:HMMER 0.2757121390 1.0000000
## GT:CUPP-AA:dbCAN_4:HMMER 0.3325623284 1.0000000
## PL:CUPP-AA:dbCAN_4:HMMER 0.2858429068 1.0000000
## CE:CUPP-AA:dbCAN_4:HMMER 0.1986226697 0.9981729
## AA:CUPP-AA:dbCAN_4:HMMER 0.1864063286 0.9927420
## CBM:CUPP-AA:dbCAN_4:HMMER -0.5369197510 0.0000000
## GH:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 0.3133125027 0.1644033
## GT:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 0.3163037339 0.6020537
## PL:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 0.3875057275 0.9896708
## CE:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 0.3601476366 1.0000000
## AA:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 0.3472311555 1.0000000
## CBM:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 0.2621525610 0.9999963
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 0.2745484438 0.7777380
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 0.2742251165 0.9916217
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 0.3757152685 0.9975892
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 0.2401332222 1.0000000
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 0.3266857648 1.0000000
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 0.2148976169 1.0000000
## GH:CUPP-CBM:dbCAN_4:HMMER 0.1954816681 1.0000000
## GT:CUPP-CBM:dbCAN_4:HMMER 0.2592784337 0.9996309
## PL:CUPP-CBM:dbCAN_4:HMMER 0.2342745898 1.0000000
## CE:CUPP-CBM:dbCAN_4:HMMER 0.1537920531 0.9969618
## AA:CUPP-CBM:dbCAN_4:HMMER 0.1429506528 0.9863958
## CBM:CUPP-CBM:dbCAN_4:HMMER -0.6054584887 0.0000000
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND 0.1342420845 1.0000000
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND 0.2164889093 1.0000000
## CE:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND 0.1917531673 0.9999999
## AA:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND 0.1793417216 0.9999872
## CBM:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND 0.0830350503 0.9908529
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 0.0876177399 0.9999993
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 0.0921634671 0.9999133
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 0.2046984504 1.0000000
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 0.0712558000 0.6041176
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 0.1587963309 0.9994243
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 0.0356127236 0.4269900
## GH:CUPP-GH:dbCAN_4:DIAMOND 0.0087130978 0.1132576
## GT:CUPP-GH:dbCAN_4:DIAMOND 0.0773342629 0.9945607
## PL:CUPP-GH:dbCAN_4:DIAMOND 0.0632577716 0.5935411
## CE:CUPP-GH:dbCAN_4:DIAMOND -0.0146024162 0.0242286
## AA:CUPP-GH:dbCAN_4:DIAMOND -0.0249387810 0.0144889
## CBM:CUPP-GH:dbCAN_4:DIAMOND -0.7845759994 0.0000000
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4:DIAMOND 0.2442380671 1.0000000
## CE:dbCAN_4:DIAMOND-GT:dbCAN_4:DIAMOND 0.2179790308 1.0000000
## AA:dbCAN_4:DIAMOND-GT:dbCAN_4:DIAMOND 0.2052763654 0.9999999
## CBM:dbCAN_4:DIAMOND-GT:dbCAN_4:DIAMOND 0.1156279353 0.9999490
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 0.1251248818 1.0000000
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 0.1265772344 1.0000000
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 0.2324476082 1.0000000
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 0.0977607780 0.8382424
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 0.1847309747 0.9999812
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 0.0683081933 0.8678259
## GH:CUPP-GT:dbCAN_4:DIAMOND 0.0461154883 0.7124795
## GT:CUPP-GT:dbCAN_4:DIAMOND 0.1116746862 0.9999920
## PL:CUPP-GT:dbCAN_4:DIAMOND 0.0910069294 0.8574045
## CE:CUPP-GT:dbCAN_4:DIAMOND 0.0116234473 0.0831274
## AA:CUPP-GT:dbCAN_4:DIAMOND 0.0009958628 0.0522498
## CBM:CUPP-GT:dbCAN_4:DIAMOND -0.7519831144 0.0000000
## CE:dbCAN_4:DIAMOND-PL:dbCAN_4:DIAMOND 0.2747617712 1.0000000
## AA:dbCAN_4:DIAMOND-PL:dbCAN_4:DIAMOND 0.2609469279 1.0000000
## CBM:dbCAN_4:DIAMOND-PL:dbCAN_4:DIAMOND 0.1929245524 1.0000000
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 0.2139550906 1.0000000
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 0.2085293466 1.0000000
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 0.2947898746 1.0000000
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 0.1555945287 0.9825508
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 0.2404015371 0.9999998
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 0.1458800837 0.9990890
## GH:CUPP-PL:dbCAN_4:DIAMOND 0.1347322101 0.9993416
## GT:CUPP-PL:dbCAN_4:DIAMOND 0.1934484640 1.0000000
## PL:CUPP-PL:dbCAN_4:DIAMOND 0.1533491959 0.9910929
## CE:CUPP-PL:dbCAN_4:DIAMOND 0.0684061877 0.3984450
## AA:CUPP-PL:dbCAN_4:DIAMOND 0.0566664252 0.2956685
## CBM:CUPP-PL:dbCAN_4:DIAMOND -0.6746864973 0.0000000
## AA:dbCAN_4:DIAMOND-CE:dbCAN_4:DIAMOND 0.3423937154 1.0000000
## CBM:dbCAN_4:DIAMOND-CE:dbCAN_4:DIAMOND 0.2810373043 1.0000000
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 0.3048078411 1.0000000
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 0.2978128891 1.0000000
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 0.3785138911 1.0000000
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 0.2378014511 0.9999972
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 0.3218483247 1.0000000
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 0.2340645717 1.0000000
## GH:CUPP-CE:dbCAN_4:DIAMOND 0.2255390469 1.0000000
## GT:CUPP-CE:dbCAN_4:DIAMOND 0.2826888029 1.0000000
## PL:CUPP-CE:dbCAN_4:DIAMOND 0.2370732124 0.9999998
## CE:CUPP-CE:dbCAN_4:DIAMOND 0.1502463961 0.9414622
## AA:CUPP-CE:dbCAN_4:DIAMOND 0.1381132128 0.8833558
## CBM:CUPP-CE:dbCAN_4:DIAMOND -0.5865737454 0.0000000
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND 0.3075813744 1.0000000
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 0.3318796929 1.0000000
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 0.3245848373 1.0000000
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 0.4041736613 1.0000000
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 0.2631450079 1.0000000
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 0.3470315163 1.0000000
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 0.2606227042 1.0000000
## GH:CUPP-AA:dbCAN_4:DIAMOND 0.2526022148 1.0000000
## GT:CUPP-AA:dbCAN_4:DIAMOND 0.3094524042 1.0000000
## PL:CUPP-AA:dbCAN_4:DIAMOND 0.2627329826 1.0000000
## CE:CUPP-AA:dbCAN_4:DIAMOND 0.1755127455 0.9862573
## AA:CUPP-AA:dbCAN_4:DIAMOND 0.1632964044 0.9633995
## CBM:CUPP-AA:dbCAN_4:DIAMOND -0.5600296752 0.0000000
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 0.2108268782 1.0000000
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 0.2103975985 1.0000000
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 0.3116124772 1.0000000
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 0.1759720695 0.9999337
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 0.2624971750 1.0000000
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 0.1510053009 1.0000000
## GH:CUPP-CBM:dbCAN_4:DIAMOND 0.1317567348 1.0000000
## GT:CUPP-CBM:dbCAN_4:DIAMOND 0.1954482376 1.0000000
## PL:CUPP-CBM:dbCAN_4:DIAMOND 0.1701717984 0.9999916
## CE:CUPP-CBM:dbCAN_4:DIAMOND 0.0896175257 0.7162487
## AA:CUPP-CBM:dbCAN_4:DIAMOND 0.0787620631 0.5841667
## CBM:CUPP-CBM:dbCAN_4:DIAMOND -0.6693548096 0.0000000
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub 0.1298151752 1.0000000
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub 0.2425636455 1.0000000
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub 0.1091585588 0.9387570
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub 0.1967161236 0.9999999
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub 0.0733218139 0.9640834
## GH:CUPP-GH:dbCAN_4:dbCAN-sub 0.0462600546 0.8568951
## GT:CUPP-GH:dbCAN_4:dbCAN-sub 0.1149884596 1.0000000
## PL:CUPP-GH:dbCAN_4:dbCAN-sub 0.1011229668 0.9524872
## CE:CUPP-GH:dbCAN_4:dbCAN-sub 0.0233086926 0.1381279
## AA:CUPP-GH:dbCAN_4:dbCAN-sub 0.0129810117 0.0887343
## CBM:CUPP-GH:dbCAN_4:dbCAN-sub -0.7468635413 0.0000000
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:dbCAN-sub 0.2745262256 1.0000000
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4:dbCAN-sub 0.1398393954 0.9939551
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4:dbCAN-sub 0.2268095921 1.0000000
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4:dbCAN-sub 0.1103868107 0.9998151
## GH:CUPP-GT:dbCAN_4:dbCAN-sub 0.0881941057 0.9996863
## GT:CUPP-GT:dbCAN_4:dbCAN-sub 0.1537533036 1.0000000
## PL:CUPP-GT:dbCAN_4:dbCAN-sub 0.1330855468 0.9973271
## CE:CUPP-GT:dbCAN_4:dbCAN-sub 0.0537020647 0.3613226
## AA:CUPP-GT:dbCAN_4:dbCAN-sub 0.0430744802 0.2558746
## CBM:CUPP-GT:dbCAN_4:dbCAN-sub -0.7099044970 0.0000000
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4:dbCAN-sub 0.1673849877 0.9936659
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4:dbCAN-sub 0.2521919961 1.0000000
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4:dbCAN-sub 0.1576705427 0.9998836
## GH:CUPP-PL:dbCAN_4:dbCAN-sub 0.1465226690 0.9999386
## GT:CUPP-PL:dbCAN_4:dbCAN-sub 0.2052389229 1.0000000
## PL:CUPP-PL:dbCAN_4:dbCAN-sub 0.1651396548 0.9973977
## CE:CUPP-PL:dbCAN_4:dbCAN-sub 0.0801966466 0.5047535
## AA:CUPP-PL:dbCAN_4:dbCAN-sub 0.0684568841 0.3885782
## CBM:CUPP-PL:dbCAN_4:dbCAN-sub -0.6628960384 0.0000000
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4:dbCAN-sub 0.4307506889 1.0000000
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4:dbCAN-sub 0.3416758426 1.0000000
## GH:CUPP-CE:dbCAN_4:dbCAN-sub 0.3326673649 0.9999999
## GT:CUPP-CE:dbCAN_4:dbCAN-sub 0.3901042098 0.9992205
## PL:CUPP-CE:dbCAN_4:dbCAN-sub 0.3455316551 1.0000000
## CE:CUPP-CE:dbCAN_4:dbCAN-sub 0.2590715528 1.0000000
## AA:CUPP-CE:dbCAN_4:dbCAN-sub 0.2470155770 0.9999991
## CBM:CUPP-CE:dbCAN_4:dbCAN-sub -0.4789490998 0.0000000
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub 0.2811680949 1.0000000
## GH:CUPP-AA:dbCAN_4:dbCAN-sub 0.2731476055 1.0000000
## GT:CUPP-AA:dbCAN_4:dbCAN-sub 0.3299977949 1.0000000
## PL:CUPP-AA:dbCAN_4:dbCAN-sub 0.2832783733 1.0000000
## CE:CUPP-AA:dbCAN_4:dbCAN-sub 0.1960581362 0.9976388
## AA:CUPP-AA:dbCAN_4:dbCAN-sub 0.1838417951 0.9910806
## CBM:CUPP-AA:dbCAN_4:dbCAN-sub -0.5394842845 0.0000000
## GH:CUPP-CBM:dbCAN_4:dbCAN-sub 0.1770621725 1.0000000
## GT:CUPP-CBM:dbCAN_4:dbCAN-sub 0.2408589381 0.9999988
## PL:CUPP-CBM:dbCAN_4:dbCAN-sub 0.2158550942 1.0000000
## CE:CUPP-CBM:dbCAN_4:dbCAN-sub 0.1353725575 0.9800230
## AA:CUPP-CBM:dbCAN_4:dbCAN-sub 0.1245311572 0.9428213
## CBM:CUPP-CBM:dbCAN_4:dbCAN-sub -0.6238779843 0.0000000
## GT:CUPP-GH:CUPP 0.1951650975 0.9999993
## PL:CUPP-GH:CUPP 0.1810886062 1.0000000
## CE:CUPP-GH:CUPP 0.1032284184 0.8911247
## AA:CUPP-GH:CUPP 0.0928920536 0.7894844
## CBM:CUPP-GH:CUPP -0.6667451648 0.0000000
## PL:CUPP-GT:CUPP 0.1489322651 0.9997978
## CE:CUPP-GT:CUPP 0.0695055794 0.5286509
## AA:CUPP-GT:CUPP 0.0588696479 0.3981830
## CBM:CUPP-GT:CUPP -0.6939262570 0.0000000
## CE:CUPP-PL:CUPP 0.2216373254 0.9999947
## AA:CUPP-PL:CUPP 0.2098975629 0.9999218
## CBM:CUPP-PL:CUPP -0.5214553596 0.0000000
## AA:CUPP-CE:CUPP 0.3444687962 1.0000000
## CBM:CUPP-CE:CUPP -0.3802181619 0.0000000
## CBM:CUPP-AA:CUPP -0.3557491726 0.000000010.2.5 F1-score
| CAZy_class | Prediction_tool | Mean | Standard Deviation | Lower CI | Upper CI |
|---|---|---|---|---|---|
| GH | dbCAN_4 | 0.9200 | 0.2349 | 0.8804 | 0.9597 |
| GH | dbCAN_4:HMMER | 0.8927 | 0.2643 | 0.8483 | 0.9370 |
| GH | dbCAN_4:DIAMOND | 0.9485 | 0.1730 | 0.9190 | 0.9779 |
| GH | dbCAN_4:dbCAN-sub | 0.9079 | 0.2481 | 0.8661 | 0.9496 |
| GH | CUPP | 0.8005 | 0.3601 | 0.7392 | 0.8618 |
| GT | dbCAN_4 | 0.8923 | 0.2395 | 0.8376 | 0.9471 |
| GT | dbCAN_4:HMMER | 0.8503 | 0.2674 | 0.7897 | 0.9110 |
| GT | dbCAN_4:DIAMOND | 0.9263 | 0.1884 | 0.8832 | 0.9693 |
| GT | dbCAN_4:dbCAN-sub | 0.8915 | 0.2396 | 0.8368 | 0.9463 |
| GT | CUPP | 0.8230 | 0.2883 | 0.7567 | 0.8893 |
| PL | dbCAN_4 | 0.9135 | 0.2222 | 0.8174 | 1.0096 |
| PL | dbCAN_4:HMMER | 0.9135 | 0.2222 | 0.8174 | 1.0096 |
| PL | dbCAN_4:DIAMOND | 0.9489 | 0.1312 | 0.8922 | 1.0057 |
| PL | dbCAN_4:dbCAN-sub | 0.9139 | 0.2223 | 0.8177 | 1.0100 |
| PL | CUPP | 0.7307 | 0.4094 | 0.5537 | 0.9077 |
| CE | dbCAN_4 | 0.8015 | 0.3232 | 0.6408 | 0.9622 |
| CE | dbCAN_4:HMMER | 0.7905 | 0.3222 | 0.6303 | 0.9508 |
| CE | dbCAN_4:DIAMOND | 0.9041 | 0.1502 | 0.8269 | 0.9814 |
| CE | dbCAN_4:dbCAN-sub | 0.8015 | 0.3232 | 0.6408 | 0.9622 |
| CE | CUPP | 0.6880 | 0.4173 | 0.4734 | 0.9025 |
| AA | dbCAN_4 | 0.8626 | 0.2485 | 0.7302 | 0.9950 |
| AA | dbCAN_4:HMMER | 0.8577 | 0.2494 | 0.7248 | 0.9906 |
| AA | dbCAN_4:DIAMOND | 0.8972 | 0.1371 | 0.8242 | 0.9703 |
| AA | dbCAN_4:dbCAN-sub | 0.8600 | 0.2489 | 0.7273 | 0.9926 |
| AA | CUPP | 0.6685 | 0.4320 | 0.4383 | 0.8987 |
| CBM | dbCAN_4 | 0.8144 | 0.3410 | 0.7231 | 0.9057 |
| CBM | dbCAN_4:HMMER | 0.7349 | 0.3862 | 0.6314 | 0.8383 |
| CBM | dbCAN_4:DIAMOND | 0.8581 | 0.2917 | 0.7793 | 0.9370 |
| CBM | dbCAN_4:dbCAN-sub | 0.7832 | 0.3592 | 0.6870 | 0.8794 |
| CBM | CUPP | 0.0000 | 0.0000 | 0.0000 | 0.0000 |
Figure 10.9: 95% confidence intervals of the F1-score of CAZy family classification across all CAZy families per CAZy class, for each CAZyme classifier.
Figure 10.10: Scatter plot of overlaying a one-dimensional box-and-whisker plot of F1-score for each CAZy family for each CAZyme classifier. Each CAZy family is represented as a single point on the plot.
Test for significant differences between the means of the tools using a one-way ANOVA.
## Df Sum Sq Mean Sq F value Pr(>F)
## Prediction_tool 4 14.77 3.693 40.06 <2e-16 ***
## Residuals 1620 149.37 0.092
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1The means are statistically significantly different, therefore, use a post hoc Turkey HSD test to determine between which tools the means are significantly difference.
## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistical_parameter ~ Prediction_tool, data = fam_subset_f1_all)
##
## $Prediction_tool
## diff lwr upr
## dbCAN_4:HMMER-dbCAN_4 -0.03552923 -0.100331009 0.02927255
## dbCAN_4:DIAMOND-dbCAN_4 0.03733438 -0.027817025 0.10248579
## dbCAN_4:dbCAN-sub-dbCAN_4 -0.01064838 -0.075548713 0.05425196
## CUPP-dbCAN_4 -0.23454395 -0.299746394 -0.16934151
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.07286361 0.007859977 0.13786724
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.02488085 -0.039871138 0.08963284
## CUPP-dbCAN_4:HMMER -0.19901472 -0.264069507 -0.13395994
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND -0.04798276 -0.113084643 0.01711913
## CUPP-dbCAN_4:DIAMOND -0.27187833 -0.337281392 -0.20647528
## CUPP-dbCAN_4:dbCAN-sub -0.22389558 -0.289048532 -0.15874262
## p adj
## dbCAN_4:HMMER-dbCAN_4 0.5643964
## dbCAN_4:DIAMOND-dbCAN_4 0.5202789
## dbCAN_4:dbCAN-sub-dbCAN_4 0.9916713
## CUPP-dbCAN_4 0.0000000
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.0190146
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.8322065
## CUPP-dbCAN_4:HMMER 0.0000000
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND 0.2602149
## CUPP-dbCAN_4:DIAMOND 0.0000000
## CUPP-dbCAN_4:dbCAN-sub 0.0000000Now test for statistically significant differences between CAZy classes using a two-way ANOVA.
## Df Sum Sq Mean Sq F value Pr(>F)
## CAZy_class 5 14.06 2.811 38.08 <2e-16 ***
## Prediction_tool 4 14.78 3.694 50.03 <2e-16 ***
## CAZy_class:Prediction_tool 20 17.55 0.877 11.88 <2e-16 ***
## Residuals 1595 117.77 0.074
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1Statistically significant difference was detected so follow up with a Tukey test to determine if there are differences between specific groups.
## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistical_parameter ~ CAZy_class * Prediction_tool, data = fam_subset_f1_all)
##
## $`CAZy_class:Prediction_tool`
## diff lwr
## GT:dbCAN_4-GH:dbCAN_4 -2.772075e-02 -0.17367970
## PL:dbCAN_4-GH:dbCAN_4 -6.528725e-03 -0.23648422
## CE:dbCAN_4-GH:dbCAN_4 -1.185680e-01 -0.37441318
## AA:dbCAN_4-GH:dbCAN_4 -5.746505e-02 -0.32707347
## CBM:dbCAN_4-GH:dbCAN_4 -1.056751e-01 -0.26753245
## GH:dbCAN_4:HMMER-GH:dbCAN_4 -2.737927e-02 -0.15023485
## GT:dbCAN_4:HMMER-GH:dbCAN_4 -6.969663e-02 -0.21504469
## PL:dbCAN_4:HMMER-GH:dbCAN_4 -6.528725e-03 -0.23648422
## CE:dbCAN_4:HMMER-GH:dbCAN_4 -1.294985e-01 -0.38534370
## AA:dbCAN_4:HMMER-GH:dbCAN_4 -6.231412e-02 -0.33192253
## CBM:dbCAN_4:HMMER-GH:dbCAN_4 -1.851846e-01 -0.34704190
## GH:dbCAN_4:DIAMOND-GH:dbCAN_4 2.841622e-02 -0.09533950
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4 6.206026e-03 -0.13975292
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4 2.888755e-02 -0.20106794
## CE:dbCAN_4:DIAMOND-GH:dbCAN_4 -1.591188e-02 -0.27832383
## AA:dbCAN_4:DIAMOND-GH:dbCAN_4 -2.280979e-02 -0.29241820
## CBM:dbCAN_4:DIAMOND-GH:dbCAN_4 -6.192308e-02 -0.22482154
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4 -1.216397e-02 -0.13524029
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4 -2.850028e-02 -0.17445923
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4 -6.180942e-03 -0.23613644
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4 -1.185341e-01 -0.37437930
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4 -6.007328e-02 -0.32968169
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4 -1.368442e-01 -0.29870152
## GH:CUPP-GH:dbCAN_4 -1.195497e-01 -0.24330538
## GT:CUPP-GH:dbCAN_4 -9.703394e-02 -0.24361742
## PL:CUPP-GH:dbCAN_4 -1.893437e-01 -0.41929920
## CE:CUPP-GH:dbCAN_4 -2.320806e-01 -0.49449255
## AA:CUPP-GH:dbCAN_4 -2.515835e-01 -0.52119188
## CBM:CUPP-GH:dbCAN_4 -9.200444e-01 -1.08294286
## PL:dbCAN_4-GT:dbCAN_4 2.119202e-02 -0.22166736
## CE:dbCAN_4-GT:dbCAN_4 -9.084720e-02 -0.35835034
## AA:dbCAN_4-GT:dbCAN_4 -2.974430e-02 -0.31043959
## CBM:dbCAN_4-GT:dbCAN_4 -7.795438e-02 -0.25767344
## GH:dbCAN_4:HMMER-GT:dbCAN_4 3.414757e-04 -0.14524232
## GT:dbCAN_4:HMMER-GT:dbCAN_4 -4.197588e-02 -0.20698257
## PL:dbCAN_4:HMMER-GT:dbCAN_4 2.119202e-02 -0.22166736
## CE:dbCAN_4:HMMER-GT:dbCAN_4 -1.017777e-01 -0.36928086
## AA:dbCAN_4:HMMER-GT:dbCAN_4 -3.459337e-02 -0.31528866
## CBM:dbCAN_4:HMMER-GT:dbCAN_4 -1.574638e-01 -0.33718289
## GH:dbCAN_4:DIAMOND-GT:dbCAN_4 5.613697e-02 -0.09020724
## GT:dbCAN_4:DIAMOND-GT:dbCAN_4 3.392678e-02 -0.13161827
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4 5.660830e-02 -0.18625108
## CE:dbCAN_4:DIAMOND-GT:dbCAN_4 1.180887e-02 -0.26198153
## AA:dbCAN_4:DIAMOND-GT:dbCAN_4 4.910963e-03 -0.27578433
## CBM:dbCAN_4:DIAMOND-GT:dbCAN_4 -3.420233e-02 -0.21485963
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4 1.555678e-02 -0.13021335
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4 -7.795292e-04 -0.16632458
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4 2.153981e-02 -0.22131957
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4 -9.081333e-02 -0.35831646
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4 -3.235253e-02 -0.31304782
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4 -1.091234e-01 -0.28884252
## GH:CUPP-GT:dbCAN_4 -9.182891e-02 -0.23817312
## GT:CUPP-GT:dbCAN_4 -6.931319e-02 -0.23540914
## PL:CUPP-GT:dbCAN_4 -1.616230e-01 -0.40448234
## CE:CUPP-GT:dbCAN_4 -2.043598e-01 -0.47815025
## AA:CUPP-GT:dbCAN_4 -2.238627e-01 -0.50455801
## CBM:CUPP-GT:dbCAN_4 -8.923236e-01 -1.07298094
## CE:dbCAN_4-PL:dbCAN_4 -1.120392e-01 -0.43318319
## AA:dbCAN_4-PL:dbCAN_4 -5.093633e-02 -0.38314915
## CBM:dbCAN_4-PL:dbCAN_4 -9.914640e-02 -0.35188037
## GH:dbCAN_4:HMMER-PL:dbCAN_4 -2.085055e-02 -0.25056811
## GT:dbCAN_4:HMMER-PL:dbCAN_4 -6.316790e-02 -0.30566063
## PL:dbCAN_4:HMMER-PL:dbCAN_4 -1.887379e-15 -0.30092556
## CE:dbCAN_4:HMMER-PL:dbCAN_4 -1.229697e-01 -0.44411371
## AA:dbCAN_4:HMMER-PL:dbCAN_4 -5.578540e-02 -0.38799822
## CBM:dbCAN_4:HMMER-PL:dbCAN_4 -1.786558e-01 -0.43138981
## GH:dbCAN_4:DIAMOND-PL:dbCAN_4 3.494495e-02 -0.19525528
## GT:dbCAN_4:DIAMOND-PL:dbCAN_4 1.273475e-02 -0.23012463
## PL:dbCAN_4:DIAMOND-PL:dbCAN_4 3.541627e-02 -0.26550929
## CE:dbCAN_4:DIAMOND-PL:dbCAN_4 -9.383152e-03 -0.33578275
## AA:dbCAN_4:DIAMOND-PL:dbCAN_4 -1.628106e-02 -0.34849389
## CBM:dbCAN_4:DIAMOND-PL:dbCAN_4 -5.539436e-02 -0.30879636
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4 -5.635243e-03 -0.23547094
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4 -2.197155e-02 -0.26483093
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4 3.477826e-04 -0.30057778
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4 -1.120054e-01 -0.43314931
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4 -5.354456e-02 -0.38575738
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4 -1.303155e-01 -0.38304944
## GH:CUPP-PL:dbCAN_4 -1.130209e-01 -0.34322116
## GT:CUPP-PL:dbCAN_4 -9.050522e-02 -0.33374045
## PL:CUPP-PL:dbCAN_4 -1.828150e-01 -0.48374055
## CE:CUPP-PL:dbCAN_4 -2.255519e-01 -0.55195147
## AA:CUPP-PL:dbCAN_4 -2.450547e-01 -0.57726757
## CBM:CUPP-PL:dbCAN_4 -9.135157e-01 -1.16691767
## AA:dbCAN_4-CE:dbCAN_4 6.110290e-02 -0.28952883
## CBM:dbCAN_4-CE:dbCAN_4 1.289283e-02 -0.26360619
## GH:dbCAN_4:HMMER-CE:dbCAN_4 9.118868e-02 -0.16444271
## GT:dbCAN_4:HMMER-CE:dbCAN_4 4.887133e-02 -0.21829898
## PL:dbCAN_4:HMMER-CE:dbCAN_4 1.120392e-01 -0.20910473
## CE:dbCAN_4:HMMER-CE:dbCAN_4 -1.093052e-02 -0.35109326
## AA:dbCAN_4:HMMER-CE:dbCAN_4 5.625383e-02 -0.29437790
## CBM:dbCAN_4:HMMER-CE:dbCAN_4 -6.661662e-02 -0.34311564
## GH:dbCAN_4:DIAMOND-CE:dbCAN_4 1.469842e-01 -0.10908103
## GT:dbCAN_4:DIAMOND-CE:dbCAN_4 1.247740e-01 -0.14272916
## PL:dbCAN_4:DIAMOND-CE:dbCAN_4 1.474555e-01 -0.17368846
## CE:dbCAN_4:DIAMOND-CE:dbCAN_4 1.026561e-01 -0.24247281
## AA:dbCAN_4:DIAMOND-CE:dbCAN_4 9.575817e-02 -0.25487356
## CBM:dbCAN_4:DIAMOND-CE:dbCAN_4 5.664487e-02 -0.22046490
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4 1.064040e-01 -0.14933357
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4 9.006767e-02 -0.17743546
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4 1.123870e-01 -0.20875695
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4 3.387534e-05 -0.34012887
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4 5.849467e-02 -0.29213706
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4 -1.827625e-02 -0.29477526
## GH:CUPP-CE:dbCAN_4 -9.817108e-04 -0.25704692
## GT:CUPP-CE:dbCAN_4 2.153401e-02 -0.24631040
## PL:CUPP-CE:dbCAN_4 -7.077576e-02 -0.39191972
## CE:CUPP-CE:dbCAN_4 -1.135126e-01 -0.45864153
## AA:CUPP-CE:dbCAN_4 -1.330155e-01 -0.48364724
## CBM:CUPP-CE:dbCAN_4 -8.014764e-01 -1.07858621
## CBM:dbCAN_4-AA:dbCAN_4 -4.821007e-02 -0.33749129
## GH:dbCAN_4:HMMER-AA:dbCAN_4 3.008578e-02 -0.23931972
## GT:dbCAN_4:HMMER-AA:dbCAN_4 -1.223157e-02 -0.29260969
## PL:dbCAN_4:HMMER-AA:dbCAN_4 5.093633e-02 -0.28127649
## CE:dbCAN_4:HMMER-AA:dbCAN_4 -7.203342e-02 -0.42266515
## AA:dbCAN_4:HMMER-AA:dbCAN_4 -4.849067e-03 -0.36564614
## CBM:dbCAN_4:HMMER-AA:dbCAN_4 -1.277195e-01 -0.41700074
## GH:dbCAN_4:DIAMOND-AA:dbCAN_4 8.588128e-02 -0.18393590
## GT:dbCAN_4:DIAMOND-AA:dbCAN_4 6.367108e-02 -0.21702421
## PL:dbCAN_4:DIAMOND-AA:dbCAN_4 8.635260e-02 -0.24586022
## CE:dbCAN_4:DIAMOND-AA:dbCAN_4 4.155318e-02 -0.31389846
## AA:dbCAN_4:DIAMOND-AA:dbCAN_4 3.465527e-02 -0.32614181
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4 -4.458028e-03 -0.29432307
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4 4.530109e-02 -0.22420515
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4 2.896478e-02 -0.25173051
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4 5.128411e-02 -0.28092871
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4 -6.106902e-02 -0.41170075
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4 -2.608228e-03 -0.36340530
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4 -7.937914e-02 -0.36866037
## GH:CUPP-AA:dbCAN_4 -6.208461e-02 -0.33190179
## GT:CUPP-AA:dbCAN_4 -3.956889e-02 -0.32058943
## PL:CUPP-AA:dbCAN_4 -1.318787e-01 -0.46409148
## CE:CUPP-AA:dbCAN_4 -1.746155e-01 -0.53006718
## AA:CUPP-AA:dbCAN_4 -1.941184e-01 -0.55491549
## CBM:CUPP-AA:dbCAN_4 -8.625793e-01 -1.15244438
## GH:dbCAN_4:HMMER-CBM:dbCAN_4 7.829585e-02 -0.08322325
## GT:dbCAN_4:HMMER-CBM:dbCAN_4 3.597850e-02 -0.14324479
## PL:dbCAN_4:HMMER-CBM:dbCAN_4 9.914640e-02 -0.15358757
## CE:dbCAN_4:HMMER-CBM:dbCAN_4 -2.382335e-02 -0.30032237
## AA:dbCAN_4:HMMER-CBM:dbCAN_4 4.336100e-02 -0.24592022
## CBM:dbCAN_4:HMMER-CBM:dbCAN_4 -7.950945e-02 -0.27236359
## GH:dbCAN_4:DIAMOND-CBM:dbCAN_4 1.340913e-01 -0.02811348
## GT:dbCAN_4:DIAMOND-CBM:dbCAN_4 1.118812e-01 -0.06783792
## PL:dbCAN_4:DIAMOND-CBM:dbCAN_4 1.345627e-01 -0.11817129
## CE:dbCAN_4:DIAMOND-CBM:dbCAN_4 8.976325e-02 -0.19282295
## AA:dbCAN_4:DIAMOND-CBM:dbCAN_4 8.286534e-02 -0.20641588
## CBM:dbCAN_4:DIAMOND-CBM:dbCAN_4 4.375204e-02 -0.14997673
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 9.351116e-02 -0.06817592
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 7.717485e-02 -0.10254422
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 9.949418e-02 -0.15323978
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 -1.285895e-02 -0.28935797
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 4.560184e-02 -0.24367938
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 -3.116907e-02 -0.22402322
## GH:CUPP-CBM:dbCAN_4 -1.387454e-02 -0.17607937
## GT:CUPP-CBM:dbCAN_4 8.641184e-03 -0.17158546
## PL:CUPP-CBM:dbCAN_4 -8.366858e-02 -0.33640255
## CE:CUPP-CBM:dbCAN_4 -1.264055e-01 -0.40899168
## AA:CUPP-CBM:dbCAN_4 -1.459083e-01 -0.43518956
## CBM:CUPP-CBM:dbCAN_4 -8.143693e-01 -1.00809805
## GT:dbCAN_4:HMMER-GH:dbCAN_4:HMMER -4.231735e-02 -0.18728868
## PL:dbCAN_4:HMMER-GH:dbCAN_4:HMMER 2.085055e-02 -0.20886701
## CE:dbCAN_4:HMMER-GH:dbCAN_4:HMMER -1.021192e-01 -0.35775058
## AA:dbCAN_4:HMMER-GH:dbCAN_4:HMMER -3.493485e-02 -0.30434035
## CBM:dbCAN_4:HMMER-GH:dbCAN_4:HMMER -1.578053e-01 -0.31932440
## GH:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 5.579550e-02 -0.06751754
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 3.358530e-02 -0.11199849
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 5.626682e-02 -0.17345073
## CE:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 1.146740e-02 -0.25073607
## AA:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 4.569487e-03 -0.26483601
## CBM:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER -3.454381e-02 -0.19710621
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 1.521531e-02 -0.10741588
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER -1.121005e-03 -0.14670480
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 2.119833e-02 -0.20851922
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER -9.115480e-02 -0.34678619
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER -3.269401e-02 -0.30209951
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER -1.094649e-01 -0.27098403
## GH:CUPP-GH:dbCAN_4:HMMER -9.217039e-02 -0.21548343
## GT:CUPP-GH:dbCAN_4:HMMER -6.965467e-02 -0.21586459
## PL:CUPP-GH:dbCAN_4:HMMER -1.619644e-01 -0.39168199
## CE:CUPP-GH:dbCAN_4:HMMER -2.047013e-01 -0.46690479
## AA:CUPP-GH:dbCAN_4:HMMER -2.242042e-01 -0.49360969
## CBM:CUPP-GH:dbCAN_4:HMMER -8.926651e-01 -1.05522753
## PL:dbCAN_4:HMMER-GT:dbCAN_4:HMMER 6.316790e-02 -0.17932483
## CE:dbCAN_4:HMMER-GT:dbCAN_4:HMMER -5.980185e-02 -0.32697215
## AA:dbCAN_4:HMMER-GT:dbCAN_4:HMMER 7.382505e-03 -0.27299561
## CBM:dbCAN_4:HMMER-GT:dbCAN_4:HMMER -1.154879e-01 -0.29471123
## GH:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 9.811285e-02 -0.04762209
## GT:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 7.590265e-02 -0.08910404
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 9.858418e-02 -0.14390855
## CE:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 5.378475e-02 -0.21968047
## AA:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 4.688684e-02 -0.23349128
## CBM:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 7.773543e-03 -0.17239056
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 5.753266e-02 -0.08762579
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 4.119635e-02 -0.12381034
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 6.351568e-02 -0.17897704
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER -4.883745e-02 -0.31600776
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 9.623344e-03 -0.27075478
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER -6.714757e-02 -0.24637086
## GH:CUPP-GT:dbCAN_4:HMMER -4.985304e-02 -0.19558798
## GT:CUPP-GT:dbCAN_4:HMMER -2.733731e-02 -0.19289670
## PL:CUPP-GT:dbCAN_4:HMMER -1.196471e-01 -0.36213981
## CE:CUPP-GT:dbCAN_4:HMMER -1.623840e-01 -0.43584919
## AA:CUPP-GT:dbCAN_4:HMMER -1.818868e-01 -0.46226496
## CBM:CUPP-GT:dbCAN_4:HMMER -8.503478e-01 -1.03051187
## CE:dbCAN_4:HMMER-PL:dbCAN_4:HMMER -1.229697e-01 -0.44411371
## AA:dbCAN_4:HMMER-PL:dbCAN_4:HMMER -5.578540e-02 -0.38799822
## CBM:dbCAN_4:HMMER-PL:dbCAN_4:HMMER -1.786558e-01 -0.43138981
## GH:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 3.494495e-02 -0.19525528
## GT:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 1.273475e-02 -0.23012463
## PL:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 3.541627e-02 -0.26550929
## CE:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER -9.383152e-03 -0.33578275
## AA:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER -1.628106e-02 -0.34849389
## CBM:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER -5.539436e-02 -0.30879636
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER -5.635243e-03 -0.23547094
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER -2.197155e-02 -0.26483093
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 3.477826e-04 -0.30057778
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER -1.120054e-01 -0.43314931
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER -5.354456e-02 -0.38575738
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER -1.303155e-01 -0.38304944
## GH:CUPP-PL:dbCAN_4:HMMER -1.130209e-01 -0.34322116
## GT:CUPP-PL:dbCAN_4:HMMER -9.050522e-02 -0.33374045
## PL:CUPP-PL:dbCAN_4:HMMER -1.828150e-01 -0.48374055
## CE:CUPP-PL:dbCAN_4:HMMER -2.255519e-01 -0.55195147
## AA:CUPP-PL:dbCAN_4:HMMER -2.450547e-01 -0.57726757
## CBM:CUPP-PL:dbCAN_4:HMMER -9.135157e-01 -1.16691767
## AA:dbCAN_4:HMMER-CE:dbCAN_4:HMMER 6.718435e-02 -0.28344738
## CBM:dbCAN_4:HMMER-CE:dbCAN_4:HMMER -5.568610e-02 -0.33218511
## GH:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 1.579147e-01 -0.09815051
## GT:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 1.357045e-01 -0.13179864
## PL:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 1.583860e-01 -0.16275793
## CE:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 1.135866e-01 -0.23154229
## AA:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 1.066887e-01 -0.24394304
## CBM:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 6.757539e-02 -0.20953437
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 1.173345e-01 -0.13840304
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 1.009982e-01 -0.16650494
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 1.233175e-01 -0.19782643
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 1.096440e-02 -0.32919835
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 6.942519e-02 -0.28120654
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER -7.345724e-03 -0.28384474
## GH:CUPP-CE:dbCAN_4:HMMER 9.948810e-03 -0.24611640
## GT:CUPP-CE:dbCAN_4:HMMER 3.246453e-02 -0.23537988
## PL:CUPP-CE:dbCAN_4:HMMER -5.984524e-02 -0.38098919
## CE:CUPP-CE:dbCAN_4:HMMER -1.025821e-01 -0.44771101
## AA:CUPP-CE:dbCAN_4:HMMER -1.220850e-01 -0.47271672
## CBM:CUPP-CE:dbCAN_4:HMMER -7.905459e-01 -1.06765569
## CBM:dbCAN_4:HMMER-AA:dbCAN_4:HMMER -1.228705e-01 -0.41215167
## GH:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 9.073034e-02 -0.17908684
## GT:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 6.852015e-02 -0.21217514
## PL:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 9.120167e-02 -0.24101115
## CE:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 4.640224e-02 -0.30904939
## AA:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 3.950433e-02 -0.32129274
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 3.910384e-04 -0.28947400
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 5.015015e-02 -0.21935609
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 3.381384e-02 -0.24688145
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 5.613318e-02 -0.27607965
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER -5.621996e-02 -0.40685169
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 2.240839e-03 -0.35855623
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER -7.453008e-02 -0.36381130
## GH:CUPP-AA:dbCAN_4:HMMER -5.723554e-02 -0.32705272
## GT:CUPP-AA:dbCAN_4:HMMER -3.471982e-02 -0.31574036
## PL:CUPP-AA:dbCAN_4:HMMER -1.270296e-01 -0.45924241
## CE:CUPP-AA:dbCAN_4:HMMER -1.697665e-01 -0.52521811
## AA:CUPP-AA:dbCAN_4:HMMER -1.892693e-01 -0.55006642
## CBM:CUPP-AA:dbCAN_4:HMMER -8.577303e-01 -1.14759532
## GH:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 2.136008e-01 0.05139596
## GT:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 1.913906e-01 0.01167153
## PL:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 2.140721e-01 -0.03866185
## CE:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 1.692727e-01 -0.11331351
## AA:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 1.623748e-01 -0.12690644
## CBM:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 1.232615e-01 -0.07046729
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 1.730206e-01 0.01133353
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 1.566843e-01 -0.02303477
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 1.790036e-01 -0.07373034
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 6.665049e-02 -0.20984852
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 1.251113e-01 -0.16416993
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 4.834037e-02 -0.14451378
## GH:CUPP-CBM:dbCAN_4:HMMER 6.563491e-02 -0.09656992
## GT:CUPP-CBM:dbCAN_4:HMMER 8.815063e-02 -0.09207602
## PL:CUPP-CBM:dbCAN_4:HMMER -4.159139e-03 -0.25689310
## CE:CUPP-CBM:dbCAN_4:HMMER -4.689603e-02 -0.32948223
## AA:CUPP-CBM:dbCAN_4:HMMER -6.639890e-02 -0.35568012
## CBM:CUPP-CBM:dbCAN_4:HMMER -7.348598e-01 -0.92858860
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND -2.221020e-02 -0.16855441
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND 4.713275e-04 -0.22972890
## CE:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND -4.432810e-02 -0.30695454
## AA:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND -5.122601e-02 -0.32104319
## CBM:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND -9.033930e-02 -0.25358306
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND -4.058019e-02 -0.16411316
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND -5.691650e-02 -0.20326071
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND -3.459716e-02 -0.26479739
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND -1.469503e-01 -0.40301551
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND -8.848950e-02 -0.35830668
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND -1.652604e-01 -0.32746525
## GH:CUPP-GH:dbCAN_4:DIAMOND -1.479659e-01 -0.27217576
## GT:CUPP-GH:dbCAN_4:DIAMOND -1.254502e-01 -0.27241726
## PL:CUPP-GH:dbCAN_4:DIAMOND -2.177599e-01 -0.44796015
## CE:CUPP-GH:dbCAN_4:DIAMOND -2.604968e-01 -0.52312326
## AA:CUPP-GH:dbCAN_4:DIAMOND -2.799997e-01 -0.54981687
## CBM:CUPP-GH:dbCAN_4:DIAMOND -9.484606e-01 -1.11170437
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4:DIAMOND 2.268152e-02 -0.22017786
## CE:dbCAN_4:DIAMOND-GT:dbCAN_4:DIAMOND -2.211790e-02 -0.29590830
## AA:dbCAN_4:DIAMOND-GT:dbCAN_4:DIAMOND -2.901581e-02 -0.30971110
## CBM:dbCAN_4:DIAMOND-GT:dbCAN_4:DIAMOND -6.812911e-02 -0.24878640
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND -1.836999e-02 -0.16414013
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND -3.470630e-02 -0.20025136
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND -1.238697e-02 -0.25524635
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND -1.247401e-01 -0.39224324
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND -6.627931e-02 -0.34697460
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND -1.430502e-01 -0.32276929
## GH:CUPP-GT:dbCAN_4:DIAMOND -1.257557e-01 -0.27209990
## GT:CUPP-GT:dbCAN_4:DIAMOND -1.032400e-01 -0.26933592
## PL:CUPP-GT:dbCAN_4:DIAMOND -1.955497e-01 -0.43840912
## CE:CUPP-GT:dbCAN_4:DIAMOND -2.382866e-01 -0.51207702
## AA:CUPP-GT:dbCAN_4:DIAMOND -2.577895e-01 -0.53848478
## CBM:CUPP-GT:dbCAN_4:DIAMOND -9.262504e-01 -1.10690772
## CE:dbCAN_4:DIAMOND-PL:dbCAN_4:DIAMOND -4.479943e-02 -0.37119902
## AA:dbCAN_4:DIAMOND-PL:dbCAN_4:DIAMOND -5.169734e-02 -0.38391016
## CBM:dbCAN_4:DIAMOND-PL:dbCAN_4:DIAMOND -9.081063e-02 -0.34421263
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -4.105152e-02 -0.27088721
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -5.738783e-02 -0.30024721
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -3.506849e-02 -0.33599405
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -1.474216e-01 -0.46856559
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -8.896083e-02 -0.42117366
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -1.657317e-01 -0.41846571
## GH:CUPP-PL:dbCAN_4:DIAMOND -1.484372e-01 -0.37863744
## GT:CUPP-PL:dbCAN_4:DIAMOND -1.259215e-01 -0.36915673
## PL:CUPP-PL:dbCAN_4:DIAMOND -2.182313e-01 -0.51915682
## CE:CUPP-PL:dbCAN_4:DIAMOND -2.609681e-01 -0.58736775
## AA:CUPP-PL:dbCAN_4:DIAMOND -2.804710e-01 -0.61268384
## CBM:CUPP-PL:dbCAN_4:DIAMOND -9.489319e-01 -1.20233395
## AA:dbCAN_4:DIAMOND-CE:dbCAN_4:DIAMOND -6.897911e-03 -0.36234955
## CBM:dbCAN_4:DIAMOND-CE:dbCAN_4:DIAMOND -4.601121e-02 -0.32919503
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 3.747908e-03 -0.25855907
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND -1.258840e-02 -0.28637880
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 9.730934e-03 -0.31666866
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND -1.026222e-01 -0.44775109
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND -4.416141e-02 -0.39961304
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND -1.209323e-01 -0.40351853
## GH:CUPP-CE:dbCAN_4:DIAMOND -1.036378e-01 -0.36626423
## GT:CUPP-CE:dbCAN_4:DIAMOND -8.112206e-02 -0.35524591
## PL:CUPP-CE:dbCAN_4:DIAMOND -1.734318e-01 -0.49983143
## CE:CUPP-CE:dbCAN_4:DIAMOND -2.161687e-01 -0.56619329
## AA:CUPP-CE:dbCAN_4:DIAMOND -2.356716e-01 -0.59112323
## CBM:CUPP-CE:dbCAN_4:DIAMOND -9.041325e-01 -1.18731635
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND -3.911330e-02 -0.32897833
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 1.064582e-02 -0.25886042
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND -5.690492e-03 -0.28638578
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 1.662884e-02 -0.31558398
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND -9.572429e-02 -0.44635602
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND -3.726349e-02 -0.39806057
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND -1.140344e-01 -0.40331563
## GH:CUPP-AA:dbCAN_4:DIAMOND -9.673988e-02 -0.36655706
## GT:CUPP-AA:dbCAN_4:DIAMOND -7.422415e-02 -0.35524470
## PL:CUPP-AA:dbCAN_4:DIAMOND -1.665339e-01 -0.49874675
## CE:CUPP-AA:dbCAN_4:DIAMOND -2.092708e-01 -0.56472245
## AA:CUPP-AA:dbCAN_4:DIAMOND -2.287737e-01 -0.58957075
## CBM:CUPP-AA:dbCAN_4:DIAMOND -8.972346e-01 -1.18709965
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 4.975911e-02 -0.11297019
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 3.342280e-02 -0.14723449
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 5.574214e-02 -0.19765986
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND -5.661100e-02 -0.33372076
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 1.849801e-03 -0.28801524
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND -7.492112e-02 -0.26864989
## GH:CUPP-CBM:dbCAN_4:DIAMOND -5.762658e-02 -0.22087033
## GT:CUPP-CBM:dbCAN_4:DIAMOND -3.511086e-02 -0.21627310
## PL:CUPP-CBM:dbCAN_4:DIAMOND -1.274206e-01 -0.38082263
## CE:CUPP-CBM:dbCAN_4:DIAMOND -1.701575e-01 -0.45334134
## AA:CUPP-CBM:dbCAN_4:DIAMOND -1.896604e-01 -0.47952542
## CBM:CUPP-CBM:dbCAN_4:DIAMOND -8.581213e-01 -1.05272078
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub -1.633631e-02 -0.16210644
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub 5.983026e-03 -0.22385267
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub -1.063701e-01 -0.36210766
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub -4.790931e-02 -0.31741555
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub -1.246802e-01 -0.28636731
## GH:CUPP-GH:dbCAN_4:dbCAN-sub -1.073857e-01 -0.23091867
## GT:CUPP-GH:dbCAN_4:dbCAN-sub -8.486997e-02 -0.23126544
## PL:CUPP-GH:dbCAN_4:dbCAN-sub -1.771797e-01 -0.40701544
## CE:CUPP-GH:dbCAN_4:dbCAN-sub -2.199166e-01 -0.48222361
## AA:CUPP-GH:dbCAN_4:dbCAN-sub -2.394195e-01 -0.50892574
## CBM:CUPP-GH:dbCAN_4:dbCAN-sub -9.078804e-01 -1.07060973
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:dbCAN-sub 2.231934e-02 -0.22054004
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4:dbCAN-sub -9.003380e-02 -0.35753693
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4:dbCAN-sub -3.157300e-02 -0.31226829
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4:dbCAN-sub -1.083439e-01 -0.28806299
## GH:CUPP-GT:dbCAN_4:dbCAN-sub -9.104939e-02 -0.23739360
## GT:CUPP-GT:dbCAN_4:dbCAN-sub -6.853366e-02 -0.23462961
## PL:CUPP-GT:dbCAN_4:dbCAN-sub -1.608434e-01 -0.40370281
## CE:CUPP-GT:dbCAN_4:dbCAN-sub -2.035803e-01 -0.47737072
## AA:CUPP-GT:dbCAN_4:dbCAN-sub -2.230832e-01 -0.50377848
## CBM:CUPP-GT:dbCAN_4:dbCAN-sub -8.915441e-01 -1.07220142
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4:dbCAN-sub -1.123531e-01 -0.43349709
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4:dbCAN-sub -5.389234e-02 -0.38610516
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4:dbCAN-sub -1.306633e-01 -0.38339722
## GH:CUPP-PL:dbCAN_4:dbCAN-sub -1.133687e-01 -0.34356894
## GT:CUPP-PL:dbCAN_4:dbCAN-sub -9.085300e-02 -0.33408823
## PL:CUPP-PL:dbCAN_4:dbCAN-sub -1.831628e-01 -0.48408833
## CE:CUPP-PL:dbCAN_4:dbCAN-sub -2.258997e-01 -0.55229925
## AA:CUPP-PL:dbCAN_4:dbCAN-sub -2.454025e-01 -0.57761535
## CBM:CUPP-PL:dbCAN_4:dbCAN-sub -9.138635e-01 -1.16726546
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4:dbCAN-sub 5.846080e-02 -0.29217093
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4:dbCAN-sub -1.831012e-02 -0.29480914
## GH:CUPP-CE:dbCAN_4:dbCAN-sub -1.015586e-03 -0.25708080
## GT:CUPP-CE:dbCAN_4:dbCAN-sub 2.150014e-02 -0.24634427
## PL:CUPP-CE:dbCAN_4:dbCAN-sub -7.080963e-02 -0.39195359
## CE:CUPP-CE:dbCAN_4:dbCAN-sub -1.135465e-01 -0.45867540
## AA:CUPP-CE:dbCAN_4:dbCAN-sub -1.330494e-01 -0.48368112
## CBM:CUPP-CE:dbCAN_4:dbCAN-sub -8.015103e-01 -1.07862009
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub -7.677092e-02 -0.36605214
## GH:CUPP-AA:dbCAN_4:dbCAN-sub -5.947638e-02 -0.32929356
## GT:CUPP-AA:dbCAN_4:dbCAN-sub -3.696066e-02 -0.31798120
## PL:CUPP-AA:dbCAN_4:dbCAN-sub -1.292704e-01 -0.46148325
## CE:CUPP-AA:dbCAN_4:dbCAN-sub -1.720073e-01 -0.52745895
## AA:CUPP-AA:dbCAN_4:dbCAN-sub -1.915102e-01 -0.55230726
## CBM:CUPP-AA:dbCAN_4:dbCAN-sub -8.599711e-01 -1.14983615
## GH:CUPP-CBM:dbCAN_4:dbCAN-sub 1.729453e-02 -0.14491030
## GT:CUPP-CBM:dbCAN_4:dbCAN-sub 3.981026e-02 -0.14041639
## PL:CUPP-CBM:dbCAN_4:dbCAN-sub -5.249951e-02 -0.30523348
## CE:CUPP-CBM:dbCAN_4:dbCAN-sub -9.523640e-02 -0.37782260
## AA:CUPP-CBM:dbCAN_4:dbCAN-sub -1.147393e-01 -0.40402049
## CBM:CUPP-CBM:dbCAN_4:dbCAN-sub -7.832002e-01 -0.97692897
## GT:CUPP-GH:CUPP 2.251572e-02 -0.12445138
## PL:CUPP-GH:CUPP -6.979405e-02 -0.29999427
## CE:CUPP-GH:CUPP -1.125309e-01 -0.37515737
## AA:CUPP-GH:CUPP -1.320338e-01 -0.40185098
## CBM:CUPP-GH:CUPP -8.004947e-01 -0.96373849
## PL:CUPP-GT:CUPP -9.230977e-02 -0.33554500
## CE:CUPP-GT:CUPP -1.350467e-01 -0.40917050
## AA:CUPP-GT:CUPP -1.545495e-01 -0.43557007
## CBM:CUPP-GT:CUPP -8.230105e-01 -1.00417270
## CE:CUPP-PL:CUPP -4.273689e-02 -0.36913649
## AA:CUPP-PL:CUPP -6.223976e-02 -0.39445258
## CBM:CUPP-PL:CUPP -7.307007e-01 -0.98410269
## AA:CUPP-CE:CUPP -1.950287e-02 -0.37495451
## CBM:CUPP-CE:CUPP -6.879638e-01 -0.97114762
## CBM:CUPP-AA:CUPP -6.684609e-01 -0.95832597
## upr p adj
## GT:dbCAN_4-GH:dbCAN_4 0.118238197 1.0000000
## PL:dbCAN_4-GH:dbCAN_4 0.223426768 1.0000000
## CE:dbCAN_4-GH:dbCAN_4 0.137277269 0.9972009
## AA:dbCAN_4-GH:dbCAN_4 0.212143358 1.0000000
## CBM:dbCAN_4-GH:dbCAN_4 0.056182199 0.8118457
## GH:dbCAN_4:HMMER-GH:dbCAN_4 0.095476297 1.0000000
## GT:dbCAN_4:HMMER-GH:dbCAN_4 0.075651434 0.9952089
## PL:dbCAN_4:HMMER-GH:dbCAN_4 0.223426768 1.0000000
## CE:dbCAN_4:HMMER-GH:dbCAN_4 0.126346748 0.9893199
## AA:dbCAN_4:HMMER-GH:dbCAN_4 0.207294291 1.0000000
## CBM:dbCAN_4:HMMER-GH:dbCAN_4 -0.023327247 0.0064695
## GH:dbCAN_4:DIAMOND-GH:dbCAN_4 0.152171943 1.0000000
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4 0.152164972 1.0000000
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4 0.258843043 1.0000000
## CE:dbCAN_4:DIAMOND-GH:dbCAN_4 0.246500077 1.0000000
## AA:dbCAN_4:DIAMOND-GH:dbCAN_4 0.246798625 1.0000000
## CBM:dbCAN_4:DIAMOND-GH:dbCAN_4 0.100975380 0.9999206
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4 0.110912356 1.0000000
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4 0.117458668 1.0000000
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4 0.223774551 1.0000000
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4 0.137311144 0.9972137
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4 0.209535130 1.0000000
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4 0.025013125 0.2648265
## GH:CUPP-GH:dbCAN_4 0.004206056 0.0759209
## GT:CUPP-GH:dbCAN_4 0.049549535 0.7897391
## PL:CUPP-GH:dbCAN_4 0.040611783 0.3188611
## CE:CUPP-GH:dbCAN_4 0.030331356 0.1844727
## AA:CUPP-GH:dbCAN_4 0.018024945 0.1107805
## CBM:CUPP-GH:dbCAN_4 -0.757145936 0.0000000
## PL:dbCAN_4-GT:dbCAN_4 0.264051405 1.0000000
## CE:dbCAN_4-GT:dbCAN_4 0.176655932 0.9999922
## AA:dbCAN_4-GT:dbCAN_4 0.250950985 1.0000000
## CBM:dbCAN_4-GT:dbCAN_4 0.101764691 0.9990772
## GH:dbCAN_4:HMMER-GT:dbCAN_4 0.145925269 1.0000000
## GT:dbCAN_4:HMMER-GT:dbCAN_4 0.123030815 1.0000000
## PL:dbCAN_4:HMMER-GT:dbCAN_4 0.264051405 1.0000000
## CE:dbCAN_4:HMMER-GT:dbCAN_4 0.165725411 0.9999192
## AA:dbCAN_4:HMMER-GT:dbCAN_4 0.246101918 1.0000000
## CBM:dbCAN_4:HMMER-GT:dbCAN_4 0.022255245 0.1998503
## GH:dbCAN_4:DIAMOND-GT:dbCAN_4 0.202481182 0.9999052
## GT:dbCAN_4:DIAMOND-GT:dbCAN_4 0.199471826 1.0000000
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4 0.299467679 1.0000000
## CE:dbCAN_4:DIAMOND-GT:dbCAN_4 0.285599273 1.0000000
## AA:dbCAN_4:DIAMOND-GT:dbCAN_4 0.285606252 1.0000000
## CBM:dbCAN_4:DIAMOND-GT:dbCAN_4 0.146454963 1.0000000
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4 0.161326913 1.0000000
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4 0.164765521 1.0000000
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4 0.264399187 1.0000000
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4 0.176689807 0.9999922
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4 0.248342757 1.0000000
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4 0.070595618 0.9027306
## GH:CUPP-GT:dbCAN_4 0.054515296 0.8667405
## GT:CUPP-GT:dbCAN_4 0.096782760 0.9995357
## PL:CUPP-GT:dbCAN_4 0.081236420 0.7808200
## CE:CUPP-GT:dbCAN_4 0.069430552 0.5433115
## AA:CUPP-GT:dbCAN_4 0.056832572 0.3891704
## CBM:CUPP-GT:dbCAN_4 -0.711666352 0.0000000
## CE:dbCAN_4-PL:dbCAN_4 0.209104730 0.9999862
## AA:dbCAN_4-PL:dbCAN_4 0.281276494 1.0000000
## CBM:dbCAN_4-PL:dbCAN_4 0.153587566 0.9998535
## GH:dbCAN_4:HMMER-PL:dbCAN_4 0.208867007 1.0000000
## GT:dbCAN_4:HMMER-PL:dbCAN_4 0.179324826 1.0000000
## PL:dbCAN_4:HMMER-PL:dbCAN_4 0.300925561 1.0000000
## CE:dbCAN_4:HMMER-PL:dbCAN_4 0.198174209 0.9999084
## AA:dbCAN_4:HMMER-PL:dbCAN_4 0.276427428 1.0000000
## CBM:dbCAN_4:HMMER-PL:dbCAN_4 0.074078120 0.6650318
## GH:dbCAN_4:DIAMOND-PL:dbCAN_4 0.265145170 1.0000000
## GT:dbCAN_4:DIAMOND-PL:dbCAN_4 0.255594131 1.0000000
## PL:dbCAN_4:DIAMOND-PL:dbCAN_4 0.336341835 1.0000000
## CE:dbCAN_4:DIAMOND-PL:dbCAN_4 0.317016447 1.0000000
## AA:dbCAN_4:DIAMOND-PL:dbCAN_4 0.315931762 1.0000000
## CBM:dbCAN_4:DIAMOND-PL:dbCAN_4 0.198007642 1.0000000
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4 0.224200450 1.0000000
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4 0.220887826 1.0000000
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4 0.301273343 1.0000000
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4 0.209138606 0.9999863
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4 0.278668267 1.0000000
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4 0.122418492 0.9861501
## GH:CUPP-PL:dbCAN_4 0.117179284 0.9931489
## GT:CUPP-PL:dbCAN_4 0.152730019 0.9999481
## PL:CUPP-PL:dbCAN_4 0.118110576 0.9022185
## CE:CUPP-PL:dbCAN_4 0.100847726 0.7115242
## AA:CUPP-PL:dbCAN_4 0.087158081 0.5706236
## CBM:CUPP-PL:dbCAN_4 -0.660113674 0.0000000
## AA:dbCAN_4-CE:dbCAN_4 0.411734628 1.0000000
## CBM:dbCAN_4-CE:dbCAN_4 0.289391846 1.0000000
## GH:dbCAN_4:HMMER-CE:dbCAN_4 0.346820064 0.9999780
## GT:dbCAN_4:HMMER-CE:dbCAN_4 0.316041632 1.0000000
## PL:dbCAN_4:HMMER-CE:dbCAN_4 0.433183187 0.9999862
## CE:dbCAN_4:HMMER-CE:dbCAN_4 0.329232221 1.0000000
## AA:dbCAN_4:HMMER-CE:dbCAN_4 0.406885561 1.0000000
## CBM:dbCAN_4:HMMER-CE:dbCAN_4 0.209882400 1.0000000
## GH:dbCAN_4:DIAMOND-CE:dbCAN_4 0.403049385 0.9465460
## GT:dbCAN_4:DIAMOND-CE:dbCAN_4 0.392277114 0.9968952
## PL:dbCAN_4:DIAMOND-CE:dbCAN_4 0.468599462 0.9975915
## CE:dbCAN_4:DIAMOND-CE:dbCAN_4 0.447784961 0.9999996
## AA:dbCAN_4:DIAMOND-CE:dbCAN_4 0.446389895 0.9999999
## CBM:dbCAN_4:DIAMOND-CE:dbCAN_4 0.333754637 1.0000000
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4 0.362141536 0.9995602
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4 0.357570810 0.9999935
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4 0.433530970 0.9999852
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4 0.340196618 1.0000000
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4 0.409126400 1.0000000
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4 0.258222772 1.0000000
## GH:CUPP-CE:dbCAN_4 0.255083499 1.0000000
## GT:CUPP-CE:dbCAN_4 0.289378424 1.0000000
## PL:CUPP-CE:dbCAN_4 0.250368202 1.0000000
## CE:CUPP-CE:dbCAN_4 0.231616240 0.9999961
## AA:CUPP-CE:dbCAN_4 0.217616215 0.9999238
## CBM:CUPP-CE:dbCAN_4 -0.524366679 0.0000000
## CBM:dbCAN_4-AA:dbCAN_4 0.241071150 1.0000000
## GH:dbCAN_4:HMMER-AA:dbCAN_4 0.299491279 1.0000000
## GT:dbCAN_4:HMMER-AA:dbCAN_4 0.268146548 1.0000000
## PL:dbCAN_4:HMMER-AA:dbCAN_4 0.383149153 1.0000000
## CE:dbCAN_4:HMMER-AA:dbCAN_4 0.278598309 1.0000000
## AA:dbCAN_4:HMMER-AA:dbCAN_4 0.355948006 1.0000000
## CBM:dbCAN_4:HMMER-AA:dbCAN_4 0.161561704 0.9987478
## GH:dbCAN_4:DIAMOND-AA:dbCAN_4 0.355698455 0.9999981
## GT:dbCAN_4:DIAMOND-AA:dbCAN_4 0.344366370 1.0000000
## PL:dbCAN_4:DIAMOND-AA:dbCAN_4 0.418565428 1.0000000
## CE:dbCAN_4:DIAMOND-AA:dbCAN_4 0.397004813 1.0000000
## AA:dbCAN_4:DIAMOND-AA:dbCAN_4 0.395452340 1.0000000
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4 0.285407010 1.0000000
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4 0.314807326 1.0000000
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4 0.309660065 1.0000000
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4 0.383496936 1.0000000
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4 0.289562705 1.0000000
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4 0.358188845 1.0000000
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4 0.209902077 0.9999999
## GH:CUPP-AA:dbCAN_4 0.207732569 1.0000000
## GT:CUPP-AA:dbCAN_4 0.241451659 1.0000000
## PL:CUPP-AA:dbCAN_4 0.200334168 0.9998164
## CE:CUPP-AA:dbCAN_4 0.180836092 0.9930901
## AA:CUPP-AA:dbCAN_4 0.166678659 0.9755729
## CBM:CUPP-AA:dbCAN_4 -0.572714305 0.0000000
## GH:dbCAN_4:HMMER-CBM:dbCAN_4 0.239814953 0.9943443
## GT:dbCAN_4:HMMER-CBM:dbCAN_4 0.215201788 1.0000000
## PL:dbCAN_4:HMMER-CBM:dbCAN_4 0.351880366 0.9998535
## CE:dbCAN_4:HMMER-CBM:dbCAN_4 0.252675668 1.0000000
## AA:dbCAN_4:HMMER-CBM:dbCAN_4 0.332642225 1.0000000
## CBM:dbCAN_4:HMMER-CBM:dbCAN_4 0.113344701 0.9996278
## GH:dbCAN_4:DIAMOND-CBM:dbCAN_4 0.296296178 0.3104456
## GT:dbCAN_4:DIAMOND-CBM:dbCAN_4 0.291600218 0.8761784
## PL:dbCAN_4:DIAMOND-CBM:dbCAN_4 0.387296641 0.9786729
## CE:dbCAN_4:DIAMOND-CBM:dbCAN_4 0.372349452 0.9999982
## AA:dbCAN_4:DIAMOND-CBM:dbCAN_4 0.372146559 0.9999998
## CBM:dbCAN_4:DIAMOND-CBM:dbCAN_4 0.237480816 1.0000000
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 0.255198233 0.9418281
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 0.256893913 0.9992261
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 0.352228149 0.9998434
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 0.263640065 1.0000000
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 0.334883064 1.0000000
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 0.161685074 1.0000000
## GH:CUPP-CBM:dbCAN_4 0.148330292 1.0000000
## GT:CUPP-CBM:dbCAN_4 0.188867831 1.0000000
## PL:CUPP-CBM:dbCAN_4 0.169065381 0.9999955
## CE:CUPP-CBM:dbCAN_4 0.156180731 0.9984373
## AA:CUPP-CBM:dbCAN_4 0.143372879 0.9898428
## CBM:CUPP-CBM:dbCAN_4 -0.620640499 0.0000000
## GT:dbCAN_4:HMMER-GH:dbCAN_4:HMMER 0.102653974 0.9999997
## PL:dbCAN_4:HMMER-GH:dbCAN_4:HMMER 0.250568105 1.0000000
## CE:dbCAN_4:HMMER-GH:dbCAN_4:HMMER 0.153512184 0.9997931
## AA:dbCAN_4:HMMER-GH:dbCAN_4:HMMER 0.234470652 1.0000000
## CBM:dbCAN_4:HMMER-GH:dbCAN_4:HMMER 0.003713805 0.0665209
## GH:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 0.179108534 0.9981078
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 0.179169094 1.0000000
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 0.285984380 1.0000000
## CE:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 0.273670869 1.0000000
## AA:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 0.273974986 1.0000000
## CBM:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 0.128018598 1.0000000
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 0.137846495 1.0000000
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 0.144462789 1.0000000
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 0.250915888 1.0000000
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 0.164476581 0.9999782
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 0.236711491 1.0000000
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 0.052054177 0.7486330
## GH:CUPP-GH:dbCAN_4:HMMER 0.031142647 0.5400710
## GT:CUPP-GH:dbCAN_4:HMMER 0.076555258 0.9956682
## PL:CUPP-GH:dbCAN_4:HMMER 0.067753120 0.6705109
## CE:CUPP-GH:dbCAN_4:HMMER 0.057502148 0.4382602
## AA:CUPP-GH:dbCAN_4:HMMER 0.045201306 0.2965472
## CBM:CUPP-GH:dbCAN_4:HMMER -0.730102718 0.0000000
## PL:dbCAN_4:HMMER-GT:dbCAN_4:HMMER 0.305660628 1.0000000
## CE:dbCAN_4:HMMER-GT:dbCAN_4:HMMER 0.207368457 1.0000000
## AA:dbCAN_4:HMMER-GT:dbCAN_4:HMMER 0.287760625 1.0000000
## CBM:dbCAN_4:HMMER-GT:dbCAN_4:HMMER 0.063735344 0.8314125
## GH:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 0.243847787 0.7606931
## GT:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 0.240909343 0.9975187
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 0.341076903 0.9997126
## CE:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 0.327249971 1.0000000
## AA:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 0.327264959 1.0000000
## CBM:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 0.187937644 1.0000000
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 0.202691108 0.9998218
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 0.206203038 1.0000000
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 0.306008411 1.0000000
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 0.218332853 1.0000000
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 0.290001464 1.0000000
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 0.112075716 0.9999405
## GH:CUPP-GT:dbCAN_4:HMMER 0.095881900 0.9999909
## GT:CUPP-GT:dbCAN_4:HMMER 0.138222068 1.0000000
## PL:CUPP-GT:dbCAN_4:HMMER 0.122845643 0.9926263
## CE:CUPP-GT:dbCAN_4:HMMER 0.111081250 0.9225932
## AA:CUPP-GT:dbCAN_4:HMMER 0.098491278 0.8215784
## CBM:CUPP-GT:dbCAN_4:HMMER -0.670183672 0.0000000
## CE:dbCAN_4:HMMER-PL:dbCAN_4:HMMER 0.198174209 0.9999084
## AA:dbCAN_4:HMMER-PL:dbCAN_4:HMMER 0.276427428 1.0000000
## CBM:dbCAN_4:HMMER-PL:dbCAN_4:HMMER 0.074078120 0.6650318
## GH:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 0.265145170 1.0000000
## GT:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 0.255594131 1.0000000
## PL:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 0.336341835 1.0000000
## CE:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 0.317016447 1.0000000
## AA:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 0.315931762 1.0000000
## CBM:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 0.198007642 1.0000000
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 0.224200450 1.0000000
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 0.220887826 1.0000000
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 0.301273343 1.0000000
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 0.209138606 0.9999863
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 0.278668267 1.0000000
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 0.122418492 0.9861501
## GH:CUPP-PL:dbCAN_4:HMMER 0.117179284 0.9931489
## GT:CUPP-PL:dbCAN_4:HMMER 0.152730019 0.9999481
## PL:CUPP-PL:dbCAN_4:HMMER 0.118110576 0.9022185
## CE:CUPP-PL:dbCAN_4:HMMER 0.100847726 0.7115242
## AA:CUPP-PL:dbCAN_4:HMMER 0.087158081 0.5706236
## CBM:CUPP-PL:dbCAN_4:HMMER -0.660113674 0.0000000
## AA:dbCAN_4:HMMER-CE:dbCAN_4:HMMER 0.417816082 1.0000000
## CBM:dbCAN_4:HMMER-CE:dbCAN_4:HMMER 0.220812921 1.0000000
## GH:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 0.413979906 0.8867578
## GT:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 0.403207635 0.9889725
## PL:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 0.479529982 0.9926729
## CE:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 0.458715482 0.9999960
## AA:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 0.457320416 0.9999993
## CBM:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 0.344685158 1.0000000
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 0.373072057 0.9976212
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 0.368501331 0.9999306
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 0.444461491 0.9999032
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 0.351127138 1.0000000
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 0.420056921 1.0000000
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 0.269153293 1.0000000
## GH:CUPP-CE:dbCAN_4:HMMER 0.266014020 1.0000000
## GT:CUPP-CE:dbCAN_4:HMMER 0.300308945 1.0000000
## PL:CUPP-CE:dbCAN_4:HMMER 0.261298723 1.0000000
## CE:CUPP-CE:dbCAN_4:HMMER 0.242546761 0.9999996
## AA:CUPP-CE:dbCAN_4:HMMER 0.228546736 0.9999867
## CBM:CUPP-CE:dbCAN_4:HMMER -0.513436158 0.0000000
## CBM:dbCAN_4:HMMER-AA:dbCAN_4:HMMER 0.166410771 0.9993624
## GH:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 0.360547522 0.9999937
## GT:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 0.349215436 1.0000000
## PL:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 0.423414494 0.9999999
## CE:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 0.401853880 1.0000000
## AA:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 0.400301406 1.0000000
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 0.290256077 1.0000000
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 0.319656392 1.0000000
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 0.314509132 1.0000000
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 0.388346003 1.0000000
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 0.294411772 1.0000000
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 0.363037911 1.0000000
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 0.214751143 1.0000000
## GH:CUPP-AA:dbCAN_4:HMMER 0.212581635 1.0000000
## GT:CUPP-AA:dbCAN_4:HMMER 0.246300725 1.0000000
## PL:CUPP-AA:dbCAN_4:HMMER 0.205183235 0.9999109
## CE:CUPP-AA:dbCAN_4:HMMER 0.185685159 0.9954949
## AA:CUPP-AA:dbCAN_4:HMMER 0.171527726 0.9824831
## CBM:CUPP-AA:dbCAN_4:HMMER -0.567865239 0.0000000
## GH:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 0.375805624 0.0003375
## GT:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 0.371109663 0.0209634
## PL:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 0.466806087 0.2612253
## CE:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 0.451858898 0.9152227
## AA:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 0.451656005 0.9587676
## CBM:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 0.316990262 0.8489937
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 0.334707679 0.0194924
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 0.336403359 0.2082904
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 0.431737595 0.6609050
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 0.343149511 1.0000000
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 0.414392510 0.9991231
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 0.241194520 1.0000000
## GH:CUPP-CBM:dbCAN_4:HMMER 0.227839738 0.9997367
## GT:CUPP-CBM:dbCAN_4:HMMER 0.268377277 0.9935262
## PL:CUPP-CBM:dbCAN_4:HMMER 0.248574827 1.0000000
## CE:CUPP-CBM:dbCAN_4:HMMER 0.235690177 1.0000000
## AA:CUPP-CBM:dbCAN_4:HMMER 0.222882325 1.0000000
## CBM:CUPP-CBM:dbCAN_4:HMMER -0.541131053 0.0000000
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND 0.124134014 1.0000000
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND 0.230671550 1.0000000
## CE:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND 0.218298342 1.0000000
## AA:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND 0.218591169 1.0000000
## CBM:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND 0.072904448 0.9652341
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 0.082952783 0.9999962
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 0.089427709 0.9998760
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 0.195603058 1.0000000
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 0.109114910 0.9466855
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 0.181327674 0.9999963
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND -0.003055590 0.0392222
## GH:CUPP-GH:dbCAN_4:DIAMOND -0.023756015 0.0030393
## GT:CUPP-GH:dbCAN_4:DIAMOND 0.021516939 0.2464378
## PL:CUPP-GH:dbCAN_4:DIAMOND 0.012440291 0.0959065
## CE:CUPP-GH:dbCAN_4:DIAMOND 0.002129621 0.0553727
## AA:CUPP-GH:dbCAN_4:DIAMOND -0.010182511 0.0305041
## CBM:CUPP-GH:dbCAN_4:DIAMOND -0.785216868 0.0000000
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4:DIAMOND 0.265540904 1.0000000
## CE:dbCAN_4:DIAMOND-GT:dbCAN_4:DIAMOND 0.251672497 1.0000000
## AA:dbCAN_4:DIAMOND-GT:dbCAN_4:DIAMOND 0.251679477 1.0000000
## CBM:dbCAN_4:DIAMOND-GT:dbCAN_4:DIAMOND 0.112528188 0.9999322
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 0.127400138 1.0000000
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 0.130838746 1.0000000
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 0.230472412 1.0000000
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 0.142763032 0.9969087
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 0.214415982 1.0000000
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 0.036668842 0.3936321
## GH:CUPP-GT:dbCAN_4:DIAMOND 0.020588520 0.2340075
## GT:CUPP-GT:dbCAN_4:DIAMOND 0.062855984 0.8779689
## PL:CUPP-GT:dbCAN_4:DIAMOND 0.047309644 0.3676153
## CE:CUPP-GT:dbCAN_4:DIAMOND 0.035503777 0.2112738
## AA:CUPP-GT:dbCAN_4:DIAMOND 0.022905796 0.1301099
## CBM:CUPP-GT:dbCAN_4:DIAMOND -0.745593128 0.0000000
## CE:dbCAN_4:DIAMOND-PL:dbCAN_4:DIAMOND 0.281600172 1.0000000
## AA:dbCAN_4:DIAMOND-PL:dbCAN_4:DIAMOND 0.280515487 1.0000000
## CBM:dbCAN_4:DIAMOND-PL:dbCAN_4:DIAMOND 0.162591367 0.9999758
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 0.188784176 1.0000000
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 0.185471551 1.0000000
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 0.265857069 1.0000000
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 0.173722331 0.9976005
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 0.243251992 1.0000000
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 0.087002218 0.8050037
## GH:CUPP-PL:dbCAN_4:DIAMOND 0.081763009 0.8304345
## GT:CUPP-PL:dbCAN_4:DIAMOND 0.117313745 0.9853636
## PL:CUPP-PL:dbCAN_4:DIAMOND 0.082694301 0.6092504
## CE:CUPP-PL:dbCAN_4:DIAMOND 0.065431451 0.3834771
## AA:CUPP-PL:dbCAN_4:DIAMOND 0.051741807 0.2676363
## CBM:CUPP-PL:dbCAN_4:DIAMOND -0.695529948 0.0000000
## AA:dbCAN_4:DIAMOND-CE:dbCAN_4:DIAMOND 0.348553725 1.0000000
## CBM:dbCAN_4:DIAMOND-CE:dbCAN_4:DIAMOND 0.237172618 1.0000000
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 0.266054886 1.0000000
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 0.261201997 1.0000000
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 0.336130533 1.0000000
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 0.242506683 0.9999996
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 0.311290230 1.0000000
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 0.161653881 0.9992715
## GH:CUPP-CE:dbCAN_4:DIAMOND 0.158988653 0.9998360
## GT:CUPP-CE:dbCAN_4:DIAMOND 0.193001784 0.9999996
## PL:CUPP-CE:dbCAN_4:DIAMOND 0.152967765 0.9792335
## CE:CUPP-CE:dbCAN_4:DIAMOND 0.133855853 0.8851927
## AA:CUPP-CE:dbCAN_4:DIAMOND 0.119780044 0.7871054
## CBM:CUPP-CE:dbCAN_4:DIAMOND -0.620948698 0.0000000
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND 0.250751743 1.0000000
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 0.280152059 1.0000000
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 0.275004798 1.0000000
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 0.348841669 1.0000000
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 0.254907438 0.9999999
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 0.323533578 1.0000000
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 0.175246810 0.9998393
## GH:CUPP-AA:dbCAN_4:DIAMOND 0.173077302 0.9999756
## GT:CUPP-AA:dbCAN_4:DIAMOND 0.206796391 1.0000000
## PL:CUPP-AA:dbCAN_4:DIAMOND 0.165678901 0.9907034
## CE:CUPP-AA:dbCAN_4:DIAMOND 0.146180825 0.9293104
## AA:CUPP-AA:dbCAN_4:DIAMOND 0.132023392 0.8535246
## CBM:CUPP-AA:dbCAN_4:DIAMOND -0.607369573 0.0000000
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 0.212488418 0.9999992
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 0.214080099 1.0000000
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 0.309144140 1.0000000
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 0.220498770 1.0000000
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 0.291714839 1.0000000
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 0.118807658 0.9998889
## GH:CUPP-CBM:dbCAN_4:DIAMOND 0.105617171 0.9999823
## GT:CUPP-CBM:dbCAN_4:DIAMOND 0.146051389 1.0000000
## PL:CUPP-CBM:dbCAN_4:DIAMOND 0.125981372 0.9902795
## CE:CUPP-CBM:dbCAN_4:DIAMOND 0.113026309 0.9124805
## AA:CUPP-CBM:dbCAN_4:DIAMOND 0.100204654 0.8084818
## CBM:CUPP-CBM:dbCAN_4:DIAMOND -0.663521846 0.0000000
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub 0.129433821 1.0000000
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub 0.235818719 1.0000000
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub 0.149367441 0.9995627
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub 0.221596926 1.0000000
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub 0.037006845 0.4670808
## GH:CUPP-GH:dbCAN_4:dbCAN-sub 0.016147277 0.2133485
## GT:CUPP-GH:dbCAN_4:dbCAN-sub 0.061525493 0.9402606
## PL:CUPP-GH:dbCAN_4:dbCAN-sub 0.052655952 0.4677587
## CE:CUPP-GH:dbCAN_4:dbCAN-sub 0.042390349 0.2814861
## AA:CUPP-GH:dbCAN_4:dbCAN-sub 0.030086740 0.1774155
## CBM:CUPP-GH:dbCAN_4:dbCAN-sub -0.745151127 0.0000000
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:dbCAN-sub 0.265178717 1.0000000
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4:dbCAN-sub 0.177469336 0.9999936
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4:dbCAN-sub 0.249122287 1.0000000
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4:dbCAN-sub 0.071375147 0.9094997
## GH:CUPP-GT:dbCAN_4:dbCAN-sub 0.055294825 0.8768748
## GT:CUPP-GT:dbCAN_4:dbCAN-sub 0.097562289 0.9996222
## PL:CUPP-GT:dbCAN_4:dbCAN-sub 0.082015949 0.7889382
## CE:CUPP-GT:dbCAN_4:dbCAN-sub 0.070210082 0.5521815
## AA:CUPP-GT:dbCAN_4:dbCAN-sub 0.057612101 0.3971101
## CBM:CUPP-GT:dbCAN_4:dbCAN-sub -0.710886823 0.0000000
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4:dbCAN-sub 0.208790823 0.9999853
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4:dbCAN-sub 0.278320484 1.0000000
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4:dbCAN-sub 0.122070710 0.9856315
## GH:CUPP-PL:dbCAN_4:dbCAN-sub 0.116831501 0.9928286
## GT:CUPP-PL:dbCAN_4:dbCAN-sub 0.152382236 0.9999440
## PL:CUPP-PL:dbCAN_4:dbCAN-sub 0.117762793 0.9003540
## CE:CUPP-PL:dbCAN_4:dbCAN-sub 0.100499943 0.7084716
## AA:CUPP-PL:dbCAN_4:dbCAN-sub 0.086810299 0.5673627
## CBM:CUPP-PL:dbCAN_4:dbCAN-sub -0.660461456 0.0000000
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4:dbCAN-sub 0.409092525 1.0000000
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4:dbCAN-sub 0.258188897 1.0000000
## GH:CUPP-CE:dbCAN_4:dbCAN-sub 0.255049624 1.0000000
## GT:CUPP-CE:dbCAN_4:dbCAN-sub 0.289344548 1.0000000
## PL:CUPP-CE:dbCAN_4:dbCAN-sub 0.250334327 1.0000000
## CE:CUPP-CE:dbCAN_4:dbCAN-sub 0.231582365 0.9999961
## AA:CUPP-CE:dbCAN_4:dbCAN-sub 0.217582340 0.9999234
## CBM:CUPP-CE:dbCAN_4:dbCAN-sub -0.524400554 0.0000000
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub 0.212510304 1.0000000
## GH:CUPP-AA:dbCAN_4:dbCAN-sub 0.210340796 1.0000000
## GT:CUPP-AA:dbCAN_4:dbCAN-sub 0.244059886 1.0000000
## PL:CUPP-AA:dbCAN_4:dbCAN-sub 0.202942396 0.9998748
## CE:CUPP-AA:dbCAN_4:dbCAN-sub 0.183444320 0.9944905
## AA:CUPP-AA:dbCAN_4:dbCAN-sub 0.169286887 0.9795148
## CBM:CUPP-AA:dbCAN_4:dbCAN-sub -0.570106078 0.0000000
## GH:CUPP-CBM:dbCAN_4:dbCAN-sub 0.179499365 1.0000000
## GT:CUPP-CBM:dbCAN_4:dbCAN-sub 0.220036904 1.0000000
## PL:CUPP-CBM:dbCAN_4:dbCAN-sub 0.200234455 1.0000000
## CE:CUPP-CBM:dbCAN_4:dbCAN-sub 0.187349805 0.9999934
## AA:CUPP-CBM:dbCAN_4:dbCAN-sub 0.174541952 0.9998193
## CBM:CUPP-CBM:dbCAN_4:dbCAN-sub -0.589471426 0.0000000
## GT:CUPP-GH:CUPP 0.169482825 1.0000000
## PL:CUPP-GH:CUPP 0.160406177 0.9999994
## CE:CUPP-GH:CUPP 0.150095507 0.9992553
## AA:CUPP-GH:CUPP 0.137783375 0.9934794
## CBM:CUPP-GH:CUPP -0.637250981 0.0000000
## PL:CUPP-GT:CUPP 0.150925466 0.9999232
## CE:CUPP-GT:CUPP 0.139077192 0.9927919
## AA:CUPP-GT:CUPP 0.126471018 0.9677972
## CBM:CUPP-GT:CUPP -0.641848211 0.0000000
## CE:CUPP-PL:CUPP 0.283662711 1.0000000
## AA:CUPP-PL:CUPP 0.269973066 1.0000000
## CBM:CUPP-PL:CUPP -0.477298689 0.0000000
## AA:CUPP-CE:CUPP 0.335948765 1.0000000
## CBM:CUPP-CE:CUPP -0.404779977 0.0000000
## CBM:CUPP-AA:CUPP -0.378595892 0.000000010.2.6 Accuracy
| CAZy_class | Prediction_tool | Mean | Standard Deviation | Lower CI | Upper CI |
|---|---|---|---|---|---|
| GH | dbCAN_4 | 0.9998 | 0.0013 | 0.9995 | 1.0000 |
| GH | dbCAN_4:HMMER | 0.9996 | 0.0014 | 0.9994 | 0.9999 |
| GH | dbCAN_4:DIAMOND | 0.9998 | 0.0005 | 0.9997 | 0.9999 |
| GH | dbCAN_4:dbCAN-sub | 0.9997 | 0.0013 | 0.9995 | 1.0000 |
| GH | CUPP | 0.9996 | 0.0013 | 0.9994 | 0.9998 |
| GT | dbCAN_4 | 0.9996 | 0.0013 | 0.9993 | 0.9999 |
| GT | dbCAN_4:HMMER | 0.9992 | 0.0021 | 0.9987 | 0.9997 |
| GT | dbCAN_4:DIAMOND | 0.9997 | 0.0007 | 0.9995 | 0.9999 |
| GT | dbCAN_4:dbCAN-sub | 0.9996 | 0.0013 | 0.9992 | 0.9999 |
| GT | CUPP | 0.9992 | 0.0018 | 0.9988 | 0.9996 |
| PL | dbCAN_4 | 1.0000 | 0.0001 | 0.9999 | 1.0000 |
| PL | dbCAN_4:HMMER | 1.0000 | 0.0001 | 0.9999 | 1.0000 |
| PL | dbCAN_4:DIAMOND | 1.0000 | 0.0001 | 0.9999 | 1.0000 |
| PL | dbCAN_4:dbCAN-sub | 1.0000 | 0.0001 | 0.9999 | 1.0000 |
| PL | CUPP | 0.9999 | 0.0003 | 0.9997 | 1.0000 |
| CE | dbCAN_4 | 0.9993 | 0.0012 | 0.9988 | 0.9999 |
| CE | dbCAN_4:HMMER | 0.9992 | 0.0013 | 0.9986 | 0.9999 |
| CE | dbCAN_4:DIAMOND | 0.9994 | 0.0009 | 0.9990 | 0.9999 |
| CE | dbCAN_4:dbCAN-sub | 0.9993 | 0.0012 | 0.9988 | 0.9999 |
| CE | CUPP | 0.9992 | 0.0012 | 0.9985 | 0.9998 |
| AA | dbCAN_4 | 0.9996 | 0.0007 | 0.9992 | 0.9999 |
| AA | dbCAN_4:HMMER | 0.9996 | 0.0007 | 0.9992 | 0.9999 |
| AA | dbCAN_4:DIAMOND | 0.9995 | 0.0006 | 0.9992 | 0.9999 |
| AA | dbCAN_4:dbCAN-sub | 0.9996 | 0.0007 | 0.9992 | 0.9999 |
| AA | CUPP | 0.9993 | 0.0009 | 0.9989 | 0.9998 |
| CBM | dbCAN_4 | 0.9995 | 0.0012 | 0.9992 | 0.9998 |
| CBM | dbCAN_4:HMMER | 0.9989 | 0.0030 | 0.9981 | 0.9997 |
| CBM | dbCAN_4:DIAMOND | 0.9997 | 0.0009 | 0.9994 | 0.9999 |
| CBM | dbCAN_4:dbCAN-sub | 0.9995 | 0.0011 | 0.9992 | 0.9998 |
| CBM | CUPP | 0.9978 | 0.0037 | 0.9968 | 0.9988 |
Figure 10.11: 95% confidence intervals of the accuarcy of CAZy family classification across all CAZy families per CAZy class, for each CAZyme classifier.
Figure 10.12: Scatter plot of overlaying a one-dimensional box-and-whisker plot of the accuracy for each CAZy family for each CAZyme classifier. Each CAZy family is represented as a single point on the plot.
Test for significant differences between the means of the tools using a one-way ANOVA.
## Df Sum Sq Mean Sq F value Pr(>F)
## Prediction_tool 4 0.000065 1.637e-05 7.268 8.46e-06 ***
## Residuals 1620 0.003649 2.252e-06
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1The means are statistically significantly different, therefore, use a post hoc Turkey HSD test to determine between which tools the means are significantly difference.
## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistical_parameter ~ Prediction_tool, data = fam_subset_acc_all)
##
## $Prediction_tool
## diff lwr upr
## dbCAN_4:HMMER-dbCAN_4 -2.440928e-04 -5.643730e-04 7.618737e-05
## dbCAN_4:DIAMOND-dbCAN_4 8.830431e-05 -2.337039e-04 4.103125e-04
## dbCAN_4:dbCAN-sub-dbCAN_4 -8.719975e-06 -3.294873e-04 3.120473e-04
## CUPP-dbCAN_4 -4.628920e-04 -7.851524e-04 -1.406315e-04
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 3.323971e-04 1.111927e-05 6.536750e-04
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 2.353728e-04 -8.466127e-05 5.554070e-04
## CUPP-dbCAN_4:HMMER -2.187992e-04 -5.403298e-04 1.027315e-04
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND -9.702428e-05 -4.187877e-04 2.247392e-04
## CUPP-dbCAN_4:DIAMOND -5.511963e-04 -8.744483e-04 -2.279443e-04
## CUPP-dbCAN_4:dbCAN-sub -4.541720e-04 -7.761879e-04 -1.321561e-04
## p adj
## dbCAN_4:HMMER-dbCAN_4 0.2286580
## dbCAN_4:DIAMOND-dbCAN_4 0.9448178
## dbCAN_4:dbCAN-sub-dbCAN_4 0.9999931
## CUPP-dbCAN_4 0.0008667
## dbCAN_4:DIAMOND-dbCAN_4:HMMER 0.0384046
## dbCAN_4:dbCAN-sub-dbCAN_4:HMMER 0.2622881
## CUPP-dbCAN_4:HMMER 0.3405174
## dbCAN_4:dbCAN-sub-dbCAN_4:DIAMOND 0.9234433
## CUPP-dbCAN_4:DIAMOND 0.0000342
## CUPP-dbCAN_4:dbCAN-sub 0.0011512Now test for statistically significant differences between CAZy classes using a two-way ANOVA.
## Df Sum Sq Mean Sq F value Pr(>F)
## CAZy_class 5 0.000106 2.128e-05 9.813 2.99e-09 ***
## Prediction_tool 4 0.000066 1.641e-05 7.565 4.91e-06 ***
## CAZy_class:Prediction_tool 20 0.000083 4.136e-06 1.907 0.0091 **
## Residuals 1595 0.003460 2.169e-06
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1Statistically significant difference was detected so follow up with a Tukey test to determine if there are differences between specific groups.
## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistical_parameter ~ CAZy_class * Prediction_tool, data = fam_subset_acc_all)
##
## $`CAZy_class:Prediction_tool`
## diff lwr
## GT:dbCAN_4-GH:dbCAN_4 -1.940838e-04 -9.851816e-04
## PL:dbCAN_4-GH:dbCAN_4 1.959374e-04 -1.050422e-03
## CE:dbCAN_4-GH:dbCAN_4 -4.087401e-04 -1.795422e-03
## AA:dbCAN_4-GH:dbCAN_4 -1.767771e-04 -1.638055e-03
## CBM:dbCAN_4-GH:dbCAN_4 -2.608955e-04 -1.138163e-03
## GH:dbCAN_4:HMMER-GH:dbCAN_4 -1.157649e-04 -7.816425e-04
## GT:dbCAN_4:HMMER-GH:dbCAN_4 -5.548472e-04 -1.342634e-03
## PL:dbCAN_4:HMMER-GH:dbCAN_4 1.958787e-04 -1.050481e-03
## CE:dbCAN_4:HMMER-GH:dbCAN_4 -5.116261e-04 -1.898308e-03
## AA:dbCAN_4:HMMER-GH:dbCAN_4 -2.002618e-04 -1.661540e-03
## CBM:dbCAN_4:HMMER-GH:dbCAN_4 -8.740337e-04 -1.751301e-03
## GH:dbCAN_4:DIAMOND-GH:dbCAN_4 5.742013e-05 -6.133362e-04
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4 -5.703685e-05 -8.481347e-04
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4 1.964761e-04 -1.049883e-03
## CE:dbCAN_4:DIAMOND-GH:dbCAN_4 -3.112581e-04 -1.733532e-03
## AA:dbCAN_4:DIAMOND-GH:dbCAN_4 -2.174116e-04 -1.678690e-03
## CBM:dbCAN_4:DIAMOND-GH:dbCAN_4 -9.712150e-05 -9.800316e-04
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4 -1.131407e-05 -6.783881e-04
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4 -2.017518e-04 -9.928496e-04
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4 2.012936e-04 -1.045066e-03
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4 -4.081817e-04 -1.794863e-03
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4 -1.993389e-04 -1.660617e-03
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4 -2.713788e-04 -1.148646e-03
## GH:CUPP-GH:dbCAN_4 -1.608370e-04 -8.315934e-04
## GT:CUPP-GH:dbCAN_4 -5.369362e-04 -1.331419e-03
## PL:CUPP-GH:dbCAN_4 9.436858e-05 -1.151991e-03
## CE:CUPP-GH:dbCAN_4 -5.866177e-04 -2.008891e-03
## AA:CUPP-GH:dbCAN_4 -4.160180e-04 -1.877296e-03
## CBM:CUPP-GH:dbCAN_4 -1.939074e-03 -2.821985e-03
## PL:dbCAN_4-GT:dbCAN_4 3.900212e-04 -9.262773e-04
## CE:dbCAN_4-GT:dbCAN_4 -2.146563e-04 -1.664524e-03
## AA:dbCAN_4-GT:dbCAN_4 1.730666e-05 -1.504063e-03
## CBM:dbCAN_4-GT:dbCAN_4 -6.681177e-05 -1.040890e-03
## GH:dbCAN_4:HMMER-GT:dbCAN_4 7.831883e-05 -7.107457e-04
## GT:dbCAN_4:HMMER-GT:dbCAN_4 -3.607635e-04 -1.255100e-03
## PL:dbCAN_4:HMMER-GT:dbCAN_4 3.899625e-04 -9.263359e-04
## CE:dbCAN_4:HMMER-GT:dbCAN_4 -3.175424e-04 -1.767410e-03
## AA:dbCAN_4:HMMER-GT:dbCAN_4 -6.178074e-06 -1.527547e-03
## CBM:dbCAN_4:HMMER-GT:dbCAN_4 -6.799500e-04 -1.654028e-03
## GH:dbCAN_4:DIAMOND-GT:dbCAN_4 2.515039e-04 -5.416821e-04
## GT:dbCAN_4:DIAMOND-GT:dbCAN_4 1.370469e-04 -7.602077e-04
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4 3.905598e-04 -9.257386e-04
## CE:dbCAN_4:DIAMOND-GT:dbCAN_4 -1.171744e-04 -1.601119e-03
## AA:dbCAN_4:DIAMOND-GT:dbCAN_4 -2.332785e-05 -1.544697e-03
## CBM:dbCAN_4:DIAMOND-GT:dbCAN_4 9.696227e-05 -8.822007e-04
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4 1.827697e-04 -6.073048e-04
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4 -7.667993e-06 -9.049226e-04
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4 3.953773e-04 -9.209211e-04
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4 -2.140979e-04 -1.663966e-03
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4 -5.255176e-06 -1.526624e-03
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4 -7.729499e-05 -1.051373e-03
## GH:CUPP-GT:dbCAN_4 3.324672e-05 -7.599393e-04
## GT:CUPP-GT:dbCAN_4 -3.428524e-04 -1.243093e-03
## PL:CUPP-GT:dbCAN_4 2.884523e-04 -1.027846e-03
## CE:CUPP-GT:dbCAN_4 -3.925340e-04 -1.876479e-03
## AA:CUPP-GT:dbCAN_4 -2.219342e-04 -1.743303e-03
## CBM:CUPP-GT:dbCAN_4 -1.744991e-03 -2.724154e-03
## CE:dbCAN_4-PL:dbCAN_4 -6.046775e-04 -2.345279e-03
## AA:dbCAN_4-PL:dbCAN_4 -3.727145e-04 -2.173309e-03
## CBM:dbCAN_4-PL:dbCAN_4 -4.568329e-04 -1.826652e-03
## GH:dbCAN_4:HMMER-PL:dbCAN_4 -3.117023e-04 -1.556772e-03
## GT:dbCAN_4:HMMER-PL:dbCAN_4 -7.507846e-04 -2.065096e-03
## PL:dbCAN_4:HMMER-PL:dbCAN_4 -5.865207e-08 -1.631076e-03
## CE:dbCAN_4:HMMER-PL:dbCAN_4 -7.075635e-04 -2.448165e-03
## AA:dbCAN_4:HMMER-PL:dbCAN_4 -3.961992e-04 -2.196794e-03
## CBM:dbCAN_4:HMMER-PL:dbCAN_4 -1.069971e-03 -2.439790e-03
## GH:dbCAN_4:DIAMOND-PL:dbCAN_4 -1.385173e-04 -1.386203e-03
## GT:dbCAN_4:DIAMOND-PL:dbCAN_4 -2.529742e-04 -1.569273e-03
## PL:dbCAN_4:DIAMOND-PL:dbCAN_4 5.386674e-07 -1.630479e-03
## CE:dbCAN_4:DIAMOND-PL:dbCAN_4 -5.071955e-04 -2.276282e-03
## AA:dbCAN_4:DIAMOND-PL:dbCAN_4 -4.133490e-04 -2.213943e-03
## CBM:dbCAN_4:DIAMOND-PL:dbCAN_4 -2.930589e-04 -1.666498e-03
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4 -2.072515e-04 -1.452962e-03
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4 -3.976892e-04 -1.713988e-03
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4 5.356162e-06 -1.625661e-03
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4 -6.041191e-04 -2.344720e-03
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4 -3.952763e-04 -2.195871e-03
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4 -4.673162e-04 -1.837135e-03
## GH:CUPP-PL:dbCAN_4 -3.567744e-04 -1.604460e-03
## GT:CUPP-PL:dbCAN_4 -7.328736e-04 -2.051209e-03
## PL:CUPP-PL:dbCAN_4 -1.015688e-04 -1.732586e-03
## CE:CUPP-PL:dbCAN_4 -7.825551e-04 -2.551642e-03
## AA:CUPP-PL:dbCAN_4 -6.119554e-04 -2.412550e-03
## CBM:CUPP-PL:dbCAN_4 -2.135012e-03 -3.508451e-03
## AA:dbCAN_4-CE:dbCAN_4 2.319630e-04 -1.668462e-03
## CBM:dbCAN_4-CE:dbCAN_4 1.478445e-04 -1.350781e-03
## GH:dbCAN_4:HMMER-CE:dbCAN_4 2.929751e-04 -1.092548e-03
## GT:dbCAN_4:HMMER-CE:dbCAN_4 -1.461072e-04 -1.594171e-03
## PL:dbCAN_4:HMMER-CE:dbCAN_4 6.046188e-04 -1.135982e-03
## CE:dbCAN_4:HMMER-CE:dbCAN_4 -1.028861e-04 -1.946569e-03
## AA:dbCAN_4:HMMER-CE:dbCAN_4 2.084782e-04 -1.691947e-03
## CBM:dbCAN_4:HMMER-CE:dbCAN_4 -4.652937e-04 -1.963919e-03
## GH:dbCAN_4:DIAMOND-CE:dbCAN_4 4.661602e-04 -9.217139e-04
## GT:dbCAN_4:DIAMOND-CE:dbCAN_4 3.517032e-04 -1.098164e-03
## PL:dbCAN_4:DIAMOND-CE:dbCAN_4 6.052161e-04 -1.135385e-03
## CE:dbCAN_4:DIAMOND-CE:dbCAN_4 9.748193e-05 -1.773117e-03
## AA:dbCAN_4:DIAMOND-CE:dbCAN_4 1.913284e-04 -1.709096e-03
## CBM:dbCAN_4:DIAMOND-CE:dbCAN_4 3.116186e-04 -1.190317e-03
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4 3.974260e-04 -9.886722e-04
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4 2.069883e-04 -1.242879e-03
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4 6.100336e-04 -1.130567e-03
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4 5.584213e-07 -1.843125e-03
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4 2.094011e-04 -1.691024e-03
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4 1.373613e-04 -1.361264e-03
## GH:CUPP-CE:dbCAN_4 2.479030e-04 -1.139971e-03
## GT:CUPP-CE:dbCAN_4 -1.281961e-04 -1.579914e-03
## PL:CUPP-CE:dbCAN_4 5.031086e-04 -1.237492e-03
## CE:CUPP-CE:dbCAN_4 -1.778777e-04 -2.048477e-03
## AA:CUPP-CE:dbCAN_4 -7.277886e-06 -1.907703e-03
## CBM:CUPP-CE:dbCAN_4 -1.530334e-03 -3.032270e-03
## CBM:dbCAN_4-AA:dbCAN_4 -8.411844e-05 -1.652023e-03
## GH:dbCAN_4:HMMER-AA:dbCAN_4 6.101216e-05 -1.399166e-03
## GT:dbCAN_4:HMMER-AA:dbCAN_4 -3.780701e-04 -1.897720e-03
## PL:dbCAN_4:HMMER-AA:dbCAN_4 3.726559e-04 -1.427938e-03
## CE:dbCAN_4:HMMER-AA:dbCAN_4 -3.348490e-04 -2.235274e-03
## AA:dbCAN_4:HMMER-AA:dbCAN_4 -2.348474e-05 -1.979006e-03
## CBM:dbCAN_4:HMMER-AA:dbCAN_4 -6.972566e-04 -2.265162e-03
## GH:dbCAN_4:DIAMOND-AA:dbCAN_4 2.341972e-04 -1.228213e-03
## GT:dbCAN_4:DIAMOND-AA:dbCAN_4 1.197403e-04 -1.401629e-03
## PL:dbCAN_4:DIAMOND-AA:dbCAN_4 3.732532e-04 -1.427341e-03
## CE:dbCAN_4:DIAMOND-AA:dbCAN_4 -1.344810e-04 -2.061030e-03
## AA:dbCAN_4:DIAMOND-AA:dbCAN_4 -4.063452e-05 -1.996156e-03
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4 7.965561e-05 -1.491414e-03
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4 1.654630e-04 -1.295261e-03
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4 -2.497466e-05 -1.546344e-03
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4 3.780707e-04 -1.422524e-03
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4 -2.314045e-04 -2.131829e-03
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4 -2.256184e-05 -1.978083e-03
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4 -9.460166e-05 -1.662507e-03
## GH:CUPP-AA:dbCAN_4 1.594006e-05 -1.446470e-03
## GT:CUPP-AA:dbCAN_4 -3.601591e-04 -1.883291e-03
## PL:CUPP-AA:dbCAN_4 2.711457e-04 -1.529449e-03
## CE:CUPP-AA:dbCAN_4 -4.098406e-04 -2.336389e-03
## AA:CUPP-AA:dbCAN_4 -2.392409e-04 -2.194762e-03
## CBM:CUPP-AA:dbCAN_4 -1.762297e-03 -3.333367e-03
## GH:dbCAN_4:HMMER-CBM:dbCAN_4 1.451306e-04 -7.303033e-04
## GT:dbCAN_4:HMMER-CBM:dbCAN_4 -2.939517e-04 -1.265342e-03
## PL:dbCAN_4:HMMER-CBM:dbCAN_4 4.567743e-04 -9.130444e-04
## CE:dbCAN_4:HMMER-CBM:dbCAN_4 -2.507306e-04 -1.749356e-03
## AA:dbCAN_4:HMMER-CBM:dbCAN_4 6.063370e-05 -1.507271e-03
## CBM:dbCAN_4:HMMER-CBM:dbCAN_4 -6.131382e-04 -1.658408e-03
## GH:dbCAN_4:DIAMOND-CBM:dbCAN_4 3.183157e-04 -5.608349e-04
## GT:dbCAN_4:DIAMOND-CBM:dbCAN_4 2.038587e-04 -7.702191e-04
## PL:dbCAN_4:DIAMOND-CBM:dbCAN_4 4.573716e-04 -9.124471e-04
## CE:dbCAN_4:DIAMOND-CBM:dbCAN_4 -5.036259e-05 -1.581981e-03
## AA:dbCAN_4:DIAMOND-CBM:dbCAN_4 4.348392e-05 -1.524421e-03
## CBM:dbCAN_4:DIAMOND-CBM:dbCAN_4 1.637740e-04 -8.862364e-04
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 2.495815e-04 -6.267629e-04
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 5.914378e-05 -9.149340e-04
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 4.621891e-04 -9.076296e-04
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 -1.472861e-04 -1.645911e-03
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 6.155660e-05 -1.506348e-03
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 -1.048322e-05 -1.055753e-03
## GH:CUPP-CBM:dbCAN_4 1.000585e-04 -7.790921e-04
## GT:CUPP-CBM:dbCAN_4 -2.760407e-04 -1.252870e-03
## PL:CUPP-CBM:dbCAN_4 3.552641e-04 -1.014555e-03
## CE:CUPP-CBM:dbCAN_4 -3.257222e-04 -1.857340e-03
## AA:CUPP-CBM:dbCAN_4 -1.551224e-04 -1.723027e-03
## CBM:CUPP-CBM:dbCAN_4 -1.678179e-03 -2.728189e-03
## GT:dbCAN_4:HMMER-GH:dbCAN_4:HMMER -4.390823e-04 -1.224827e-03
## PL:dbCAN_4:HMMER-GH:dbCAN_4:HMMER 3.116437e-04 -9.334260e-04
## CE:dbCAN_4:HMMER-GH:dbCAN_4:HMMER -3.958612e-04 -1.781384e-03
## AA:dbCAN_4:HMMER-GH:dbCAN_4:HMMER -8.449690e-05 -1.544675e-03
## CBM:dbCAN_4:HMMER-GH:dbCAN_4:HMMER -7.582688e-04 -1.633703e-03
## GH:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 1.731851e-04 -4.951719e-04
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 5.872810e-05 -7.303364e-04
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 3.122410e-04 -9.328287e-04
## CE:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER -1.954932e-04 -1.616637e-03
## AA:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER -1.016467e-04 -1.561825e-03
## CBM:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 1.864345e-05 -8.624452e-04
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 1.044509e-04 -5.602105e-04
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER -8.598682e-05 -8.750514e-04
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 3.170585e-04 -9.280112e-04
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER -2.924167e-04 -1.677939e-03
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER -8.357400e-05 -1.543752e-03
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER -1.556138e-04 -1.031048e-03
## GH:CUPP-GH:dbCAN_4:HMMER -4.507210e-05 -7.134291e-04
## GT:CUPP-GH:dbCAN_4:HMMER -4.211713e-04 -1.213629e-03
## PL:CUPP-GH:dbCAN_4:HMMER 2.101335e-04 -1.034936e-03
## CE:CUPP-GH:dbCAN_4:HMMER -4.708528e-04 -1.891996e-03
## AA:CUPP-GH:dbCAN_4:HMMER -3.002530e-04 -1.760432e-03
## CBM:CUPP-GH:dbCAN_4:HMMER -1.823310e-03 -2.704398e-03
## PL:dbCAN_4:HMMER-GT:dbCAN_4:HMMER 7.507260e-04 -5.635852e-04
## CE:dbCAN_4:HMMER-GT:dbCAN_4:HMMER 4.322110e-05 -1.404843e-03
## AA:dbCAN_4:HMMER-GT:dbCAN_4:HMMER 3.545854e-04 -1.165065e-03
## CBM:dbCAN_4:HMMER-GT:dbCAN_4:HMMER -3.191865e-04 -1.290577e-03
## GH:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 6.122674e-04 -1.776164e-04
## GT:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 4.978104e-04 -3.965263e-04
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 7.513233e-04 -5.629879e-04
## CE:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 2.435891e-04 -1.238593e-03
## AA:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 3.374356e-04 -1.182215e-03
## CBM:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 4.577257e-04 -5.187641e-04
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 5.435332e-04 -2.432260e-04
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 3.530955e-04 -5.412412e-04
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 7.561408e-04 -5.581704e-04
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 1.466656e-04 -1.301398e-03
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 3.555083e-04 -1.164142e-03
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 2.834685e-04 -6.879222e-04
## GH:CUPP-GT:dbCAN_4:HMMER 3.940102e-04 -3.958736e-04
## GT:CUPP-GT:dbCAN_4:HMMER 1.791103e-05 -8.794212e-04
## PL:CUPP-GT:dbCAN_4:HMMER 6.492158e-04 -6.650954e-04
## CE:CUPP-GT:dbCAN_4:HMMER -3.177052e-05 -1.513953e-03
## AA:CUPP-GT:dbCAN_4:HMMER 1.388293e-04 -1.380821e-03
## CBM:CUPP-GT:dbCAN_4:HMMER -1.384227e-03 -2.360717e-03
## CE:dbCAN_4:HMMER-PL:dbCAN_4:HMMER -7.075049e-04 -2.448106e-03
## AA:dbCAN_4:HMMER-PL:dbCAN_4:HMMER -3.961406e-04 -2.196735e-03
## CBM:dbCAN_4:HMMER-PL:dbCAN_4:HMMER -1.069912e-03 -2.439731e-03
## GH:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER -1.384586e-04 -1.386144e-03
## GT:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER -2.529156e-04 -1.569214e-03
## PL:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 5.973195e-07 -1.630420e-03
## CE:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER -5.071369e-04 -2.276224e-03
## AA:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER -4.132904e-04 -2.213885e-03
## CBM:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER -2.930002e-04 -1.666440e-03
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER -2.071928e-04 -1.452903e-03
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER -3.976305e-04 -1.713929e-03
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 5.414814e-06 -1.625602e-03
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER -6.040604e-04 -2.344661e-03
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER -3.952177e-04 -2.195812e-03
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER -4.672575e-04 -1.837076e-03
## GH:CUPP-PL:dbCAN_4:HMMER -3.567158e-04 -1.604402e-03
## GT:CUPP-PL:dbCAN_4:HMMER -7.328149e-04 -2.051151e-03
## PL:CUPP-PL:dbCAN_4:HMMER -1.015102e-04 -1.732527e-03
## CE:CUPP-PL:dbCAN_4:HMMER -7.824965e-04 -2.551583e-03
## AA:CUPP-PL:dbCAN_4:HMMER -6.118967e-04 -2.412491e-03
## CBM:CUPP-PL:dbCAN_4:HMMER -2.134953e-03 -3.508393e-03
## AA:dbCAN_4:HMMER-CE:dbCAN_4:HMMER 3.113643e-04 -1.589061e-03
## CBM:dbCAN_4:HMMER-CE:dbCAN_4:HMMER -3.624076e-04 -1.861033e-03
## GH:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 5.690463e-04 -8.188278e-04
## GT:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 4.545893e-04 -9.952784e-04
## PL:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 7.081022e-04 -1.032499e-03
## CE:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 2.003680e-04 -1.670231e-03
## AA:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 2.942145e-04 -1.606210e-03
## CBM:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 4.145046e-04 -1.087431e-03
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 5.003121e-04 -8.857861e-04
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 3.098744e-04 -1.139993e-03
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 7.129197e-04 -1.027681e-03
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 1.034445e-04 -1.740238e-03
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 3.122872e-04 -1.588138e-03
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 2.402474e-04 -1.258378e-03
## GH:CUPP-CE:dbCAN_4:HMMER 3.507891e-04 -1.037085e-03
## GT:CUPP-CE:dbCAN_4:HMMER -2.531007e-05 -1.477027e-03
## PL:CUPP-CE:dbCAN_4:HMMER 6.059947e-04 -1.134606e-03
## CE:CUPP-CE:dbCAN_4:HMMER -7.499162e-05 -1.945591e-03
## AA:CUPP-CE:dbCAN_4:HMMER 9.560817e-05 -1.804817e-03
## CBM:CUPP-CE:dbCAN_4:HMMER -1.427448e-03 -2.929384e-03
## CBM:dbCAN_4:HMMER-AA:dbCAN_4:HMMER -6.737719e-04 -2.241677e-03
## GH:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 2.576820e-04 -1.204728e-03
## GT:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 1.432250e-04 -1.378144e-03
## PL:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 3.967379e-04 -1.403856e-03
## CE:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER -1.109963e-04 -2.037545e-03
## AA:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER -1.714978e-05 -1.972671e-03
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 1.031403e-04 -1.467929e-03
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 1.889478e-04 -1.271777e-03
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER -1.489919e-06 -1.522859e-03
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 4.015554e-04 -1.399039e-03
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER -2.079198e-04 -2.108345e-03
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 9.228983e-07 -1.954598e-03
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER -7.111692e-05 -1.639022e-03
## GH:CUPP-AA:dbCAN_4:HMMER 3.942480e-05 -1.422985e-03
## GT:CUPP-AA:dbCAN_4:HMMER -3.366744e-04 -1.859806e-03
## PL:CUPP-AA:dbCAN_4:HMMER 2.946304e-04 -1.505964e-03
## CE:CUPP-AA:dbCAN_4:HMMER -3.863559e-04 -2.312905e-03
## AA:CUPP-AA:dbCAN_4:HMMER -2.157561e-04 -2.171277e-03
## CBM:CUPP-AA:dbCAN_4:HMMER -1.738813e-03 -3.309882e-03
## GH:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 9.314539e-04 5.230327e-05
## GT:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 8.169969e-04 -1.570809e-04
## PL:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 1.070510e-03 -2.993089e-04
## CE:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 5.627756e-04 -9.688423e-04
## AA:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 6.566221e-04 -9.112828e-04
## CBM:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 7.769122e-04 -2.730982e-04
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 8.627197e-04 -1.362469e-05
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 6.722820e-04 -3.017958e-04
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 1.075327e-03 -2.944914e-04
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 4.658521e-04 -1.032773e-03
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 6.746948e-04 -8.932102e-04
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 6.026550e-04 -4.426150e-04
## GH:CUPP-CBM:dbCAN_4:HMMER 7.131967e-04 -1.659539e-04
## GT:CUPP-CBM:dbCAN_4:HMMER 3.370975e-04 -6.397313e-04
## PL:CUPP-CBM:dbCAN_4:HMMER 9.684023e-04 -4.014164e-04
## CE:CUPP-CBM:dbCAN_4:HMMER 2.874160e-04 -1.244202e-03
## AA:CUPP-CBM:dbCAN_4:HMMER 4.580158e-04 -1.109889e-03
## CBM:CUPP-CBM:dbCAN_4:HMMER -1.065041e-03 -2.115051e-03
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND -1.144570e-04 -9.076430e-04
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND 1.390559e-04 -1.108630e-03
## CE:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND -3.686783e-04 -1.792114e-03
## AA:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND -2.748318e-04 -1.737242e-03
## CBM:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND -1.545416e-04 -1.039323e-03
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND -6.873420e-05 -7.382832e-04
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND -2.591719e-04 -1.052358e-03
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 1.438734e-04 -1.103812e-03
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND -4.656018e-04 -1.853476e-03
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND -2.567591e-04 -1.719169e-03
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND -3.287989e-04 -1.207949e-03
## GH:CUPP-GH:dbCAN_4:DIAMOND -2.182572e-04 -8.914750e-04
## GT:CUPP-GH:dbCAN_4:DIAMOND -5.943563e-04 -1.390918e-03
## PL:CUPP-GH:dbCAN_4:DIAMOND 3.694845e-05 -1.210737e-03
## CE:CUPP-GH:dbCAN_4:DIAMOND -6.440379e-04 -2.067474e-03
## AA:CUPP-GH:dbCAN_4:DIAMOND -4.734381e-04 -1.935848e-03
## CBM:CUPP-GH:dbCAN_4:DIAMOND -1.996495e-03 -2.881276e-03
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4:DIAMOND 2.535129e-04 -1.062786e-03
## CE:dbCAN_4:DIAMOND-GT:dbCAN_4:DIAMOND -2.542213e-04 -1.738166e-03
## AA:dbCAN_4:DIAMOND-GT:dbCAN_4:DIAMOND -1.603748e-04 -1.681744e-03
## CBM:dbCAN_4:DIAMOND-GT:dbCAN_4:DIAMOND -4.008465e-05 -1.019248e-03
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 4.572278e-05 -7.443517e-04
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND -1.447149e-04 -1.041970e-03
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 2.583304e-04 -1.057968e-03
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND -3.511448e-04 -1.801012e-03
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND -1.423021e-04 -1.663671e-03
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND -2.143419e-04 -1.188420e-03
## GH:CUPP-GT:dbCAN_4:DIAMOND -1.038002e-04 -8.969862e-04
## GT:CUPP-GT:dbCAN_4:DIAMOND -4.798994e-04 -1.380140e-03
## PL:CUPP-GT:dbCAN_4:DIAMOND 1.514054e-04 -1.164893e-03
## CE:CUPP-GT:dbCAN_4:DIAMOND -5.295809e-04 -2.013526e-03
## AA:CUPP-GT:dbCAN_4:DIAMOND -3.589811e-04 -1.880350e-03
## CBM:CUPP-GT:dbCAN_4:DIAMOND -1.882038e-03 -2.861201e-03
## CE:dbCAN_4:DIAMOND-PL:dbCAN_4:DIAMOND -5.077342e-04 -2.276821e-03
## AA:dbCAN_4:DIAMOND-PL:dbCAN_4:DIAMOND -4.138877e-04 -2.214482e-03
## CBM:dbCAN_4:DIAMOND-PL:dbCAN_4:DIAMOND -2.935976e-04 -1.667037e-03
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -2.077901e-04 -1.453500e-03
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -3.982278e-04 -1.714526e-03
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 4.817495e-06 -1.626200e-03
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -6.046577e-04 -2.345259e-03
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -3.958150e-04 -2.196409e-03
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND -4.678548e-04 -1.837674e-03
## GH:CUPP-PL:dbCAN_4:DIAMOND -3.573131e-04 -1.604999e-03
## GT:CUPP-PL:dbCAN_4:DIAMOND -7.334123e-04 -2.051748e-03
## PL:CUPP-PL:dbCAN_4:DIAMOND -1.021075e-04 -1.733125e-03
## CE:CUPP-PL:dbCAN_4:DIAMOND -7.830938e-04 -2.552180e-03
## AA:CUPP-PL:dbCAN_4:DIAMOND -6.124940e-04 -2.413088e-03
## CBM:CUPP-PL:dbCAN_4:DIAMOND -2.135551e-03 -3.508990e-03
## AA:dbCAN_4:DIAMOND-CE:dbCAN_4:DIAMOND 9.384652e-05 -1.832702e-03
## CBM:dbCAN_4:DIAMOND-CE:dbCAN_4:DIAMOND 2.141366e-04 -1.320720e-03
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 2.999441e-04 -1.121760e-03
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 1.095064e-04 -1.374438e-03
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 5.125517e-04 -1.256535e-03
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND -9.692351e-05 -1.967523e-03
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 1.119192e-04 -1.814630e-03
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 3.987937e-05 -1.491739e-03
## GH:CUPP-CE:dbCAN_4:DIAMOND 1.504211e-04 -1.273015e-03
## GT:CUPP-CE:dbCAN_4:DIAMOND -2.256781e-04 -1.711430e-03
## PL:CUPP-CE:dbCAN_4:DIAMOND 4.056267e-04 -1.363460e-03
## CE:CUPP-CE:dbCAN_4:DIAMOND -2.753596e-04 -2.172494e-03
## AA:CUPP-CE:dbCAN_4:DIAMOND -1.047598e-04 -2.031309e-03
## CBM:CUPP-CE:dbCAN_4:DIAMOND -1.627816e-03 -3.162673e-03
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND 1.202901e-04 -1.450779e-03
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 2.060976e-04 -1.254627e-03
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 1.565986e-05 -1.505709e-03
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 4.187052e-04 -1.381889e-03
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND -1.907700e-04 -2.091195e-03
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 1.807268e-05 -1.937448e-03
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND -5.396714e-05 -1.621872e-03
## GH:CUPP-AA:dbCAN_4:DIAMOND 5.657458e-05 -1.405835e-03
## GT:CUPP-AA:dbCAN_4:DIAMOND -3.195246e-04 -1.842657e-03
## PL:CUPP-AA:dbCAN_4:DIAMOND 3.117802e-04 -1.488814e-03
## CE:CUPP-AA:dbCAN_4:DIAMOND -3.692061e-04 -2.295755e-03
## AA:CUPP-AA:dbCAN_4:DIAMOND -1.986063e-04 -2.154127e-03
## CBM:CUPP-AA:dbCAN_4:DIAMOND -1.721663e-03 -3.292732e-03
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 8.580743e-05 -7.961858e-04
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND -1.046303e-04 -1.083793e-03
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 2.984151e-04 -1.075024e-03
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND -3.110602e-04 -1.812996e-03
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND -1.022174e-04 -1.673287e-03
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND -1.742573e-04 -1.224268e-03
## GH:CUPP-CBM:dbCAN_4:DIAMOND -6.371555e-05 -9.484971e-04
## GT:CUPP-CBM:dbCAN_4:DIAMOND -4.398147e-04 -1.421715e-03
## PL:CUPP-CBM:dbCAN_4:DIAMOND 1.914901e-04 -1.181949e-03
## CE:CUPP-CBM:dbCAN_4:DIAMOND -4.894963e-04 -2.024353e-03
## AA:CUPP-CBM:dbCAN_4:DIAMOND -3.188965e-04 -1.889966e-03
## CBM:CUPP-CBM:dbCAN_4:DIAMOND -1.841953e-03 -2.896683e-03
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub -1.904377e-04 -9.805122e-04
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub 2.126076e-04 -1.033102e-03
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub -3.968676e-04 -1.782966e-03
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub -1.880249e-04 -1.648749e-03
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub -2.600647e-04 -1.136409e-03
## GH:CUPP-GH:dbCAN_4:dbCAN-sub -1.495230e-04 -8.190720e-04
## GT:CUPP-GH:dbCAN_4:dbCAN-sub -5.256221e-04 -1.319086e-03
## PL:CUPP-GH:dbCAN_4:dbCAN-sub 1.056826e-04 -1.140027e-03
## CE:CUPP-GH:dbCAN_4:dbCAN-sub -5.753037e-04 -1.997008e-03
## AA:CUPP-GH:dbCAN_4:dbCAN-sub -4.047039e-04 -1.865428e-03
## CBM:CUPP-GH:dbCAN_4:dbCAN-sub -1.927760e-03 -2.809754e-03
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:dbCAN-sub 4.030453e-04 -9.132531e-04
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4:dbCAN-sub -2.064299e-04 -1.656298e-03
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4:dbCAN-sub 2.412817e-06 -1.518956e-03
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4:dbCAN-sub -6.962700e-05 -1.043705e-03
## GH:CUPP-GT:dbCAN_4:dbCAN-sub 4.091472e-05 -7.522713e-04
## GT:CUPP-GT:dbCAN_4:dbCAN-sub -3.351844e-04 -1.235425e-03
## PL:CUPP-GT:dbCAN_4:dbCAN-sub 2.961203e-04 -1.020178e-03
## CE:CUPP-GT:dbCAN_4:dbCAN-sub -3.848660e-04 -1.868811e-03
## AA:CUPP-GT:dbCAN_4:dbCAN-sub -2.142662e-04 -1.735635e-03
## CBM:CUPP-GT:dbCAN_4:dbCAN-sub -1.737323e-03 -2.716486e-03
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4:dbCAN-sub -6.094752e-04 -2.350076e-03
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4:dbCAN-sub -4.006325e-04 -2.201227e-03
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4:dbCAN-sub -4.726723e-04 -1.842491e-03
## GH:CUPP-PL:dbCAN_4:dbCAN-sub -3.621306e-04 -1.609816e-03
## GT:CUPP-PL:dbCAN_4:dbCAN-sub -7.382298e-04 -2.056565e-03
## PL:CUPP-PL:dbCAN_4:dbCAN-sub -1.069250e-04 -1.737942e-03
## CE:CUPP-PL:dbCAN_4:dbCAN-sub -7.879113e-04 -2.556998e-03
## AA:CUPP-PL:dbCAN_4:dbCAN-sub -6.173115e-04 -2.417906e-03
## CBM:CUPP-PL:dbCAN_4:dbCAN-sub -2.140368e-03 -3.513807e-03
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4:dbCAN-sub 2.088427e-04 -1.691582e-03
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4:dbCAN-sub 1.368029e-04 -1.361822e-03
## GH:CUPP-CE:dbCAN_4:dbCAN-sub 2.473446e-04 -1.140529e-03
## GT:CUPP-CE:dbCAN_4:dbCAN-sub -1.287545e-04 -1.580472e-03
## PL:CUPP-CE:dbCAN_4:dbCAN-sub 5.025502e-04 -1.238051e-03
## CE:CUPP-CE:dbCAN_4:dbCAN-sub -1.784361e-04 -2.049036e-03
## AA:CUPP-CE:dbCAN_4:dbCAN-sub -7.836307e-06 -1.908261e-03
## CBM:CUPP-CE:dbCAN_4:dbCAN-sub -1.530893e-03 -3.032828e-03
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub -7.203982e-05 -1.639945e-03
## GH:CUPP-AA:dbCAN_4:dbCAN-sub 3.850190e-05 -1.423908e-03
## GT:CUPP-AA:dbCAN_4:dbCAN-sub -3.375973e-04 -1.860729e-03
## PL:CUPP-AA:dbCAN_4:dbCAN-sub 2.937075e-04 -1.506887e-03
## CE:CUPP-AA:dbCAN_4:dbCAN-sub -3.872788e-04 -2.313828e-03
## AA:CUPP-AA:dbCAN_4:dbCAN-sub -2.166790e-04 -2.172200e-03
## CBM:CUPP-AA:dbCAN_4:dbCAN-sub -1.739736e-03 -3.310805e-03
## GH:CUPP-CBM:dbCAN_4:dbCAN-sub 1.105417e-04 -7.686089e-04
## GT:CUPP-CBM:dbCAN_4:dbCAN-sub -2.655574e-04 -1.242386e-03
## PL:CUPP-CBM:dbCAN_4:dbCAN-sub 3.657473e-04 -1.004071e-03
## CE:CUPP-CBM:dbCAN_4:dbCAN-sub -3.152390e-04 -1.846857e-03
## AA:CUPP-CBM:dbCAN_4:dbCAN-sub -1.446392e-04 -1.712544e-03
## CBM:CUPP-CBM:dbCAN_4:dbCAN-sub -1.667696e-03 -2.717706e-03
## GT:CUPP-GH:CUPP -3.760992e-04 -1.172661e-03
## PL:CUPP-GH:CUPP 2.552056e-04 -9.924802e-04
## CE:CUPP-GH:CUPP -4.257807e-04 -1.849217e-03
## AA:CUPP-GH:CUPP -2.551809e-04 -1.717591e-03
## CBM:CUPP-GH:CUPP -1.778237e-03 -2.663019e-03
## PL:CUPP-GT:CUPP 6.313048e-04 -6.870308e-04
## CE:CUPP-GT:CUPP -4.968155e-05 -1.535434e-03
## AA:CUPP-GT:CUPP 1.209182e-04 -1.402214e-03
## CBM:CUPP-GT:CUPP -1.402138e-03 -2.384038e-03
## CE:CUPP-PL:CUPP -6.809863e-04 -2.450073e-03
## AA:CUPP-PL:CUPP -5.103865e-04 -2.310981e-03
## CBM:CUPP-PL:CUPP -2.033443e-03 -3.406883e-03
## AA:CUPP-CE:CUPP 1.705998e-04 -1.755949e-03
## CBM:CUPP-CE:CUPP -1.352457e-03 -2.887314e-03
## CBM:CUPP-AA:CUPP -1.523056e-03 -3.094126e-03
## upr p adj
## GT:dbCAN_4-GH:dbCAN_4 5.970141e-04 1.0000000
## PL:dbCAN_4-GH:dbCAN_4 1.442297e-03 1.0000000
## CE:dbCAN_4-GH:dbCAN_4 9.779417e-04 0.9999997
## AA:dbCAN_4-GH:dbCAN_4 1.284501e-03 1.0000000
## CBM:dbCAN_4-GH:dbCAN_4 6.163716e-04 0.9999996
## GH:dbCAN_4:HMMER-GH:dbCAN_4 5.501126e-04 1.0000000
## GT:dbCAN_4:HMMER-GH:dbCAN_4 2.329396e-04 0.6727377
## PL:dbCAN_4:HMMER-GH:dbCAN_4 1.442238e-03 1.0000000
## CE:dbCAN_4:HMMER-GH:dbCAN_4 8.750556e-04 0.9999562
## AA:dbCAN_4:HMMER-GH:dbCAN_4 1.261016e-03 1.0000000
## CBM:dbCAN_4:HMMER-GH:dbCAN_4 3.233368e-06 0.0523838
## GH:dbCAN_4:DIAMOND-GH:dbCAN_4 7.281764e-04 1.0000000
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4 7.340610e-04 1.0000000
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4 1.442835e-03 1.0000000
## CE:dbCAN_4:DIAMOND-GH:dbCAN_4 1.111015e-03 1.0000000
## AA:dbCAN_4:DIAMOND-GH:dbCAN_4 1.243867e-03 1.0000000
## CBM:dbCAN_4:DIAMOND-GH:dbCAN_4 7.857886e-04 1.0000000
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4 6.557599e-04 1.0000000
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4 5.893461e-04 1.0000000
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4 1.447653e-03 1.0000000
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4 9.785001e-04 0.9999997
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4 1.261939e-03 1.0000000
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4 6.058883e-04 0.9999990
## GH:CUPP-GH:dbCAN_4 5.099193e-04 1.0000000
## GT:CUPP-GH:dbCAN_4 2.575466e-04 0.7537370
## PL:CUPP-GH:dbCAN_4 1.340728e-03 1.0000000
## CE:CUPP-GH:dbCAN_4 8.356557e-04 0.9996250
## AA:CUPP-GH:dbCAN_4 1.045260e-03 0.9999999
## CBM:CUPP-GH:dbCAN_4 -1.056164e-03 0.0000000
## PL:dbCAN_4-GT:dbCAN_4 1.706320e-03 0.9999996
## CE:dbCAN_4-GT:dbCAN_4 1.235211e-03 1.0000000
## AA:dbCAN_4-GT:dbCAN_4 1.538676e-03 1.0000000
## CBM:dbCAN_4-GT:dbCAN_4 9.072660e-04 1.0000000
## GH:dbCAN_4:HMMER-GT:dbCAN_4 8.673834e-04 1.0000000
## GT:dbCAN_4:HMMER-GT:dbCAN_4 5.335732e-04 0.9997515
## PL:dbCAN_4:HMMER-GT:dbCAN_4 1.706261e-03 0.9999996
## CE:dbCAN_4:HMMER-GT:dbCAN_4 1.132325e-03 1.0000000
## AA:dbCAN_4:HMMER-GT:dbCAN_4 1.515191e-03 1.0000000
## CBM:dbCAN_4:HMMER-GT:dbCAN_4 2.941278e-04 0.6912295
## GH:dbCAN_4:DIAMOND-GT:dbCAN_4 1.044690e-03 0.9999983
## GT:dbCAN_4:DIAMOND-GT:dbCAN_4 1.034302e-03 1.0000000
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4 1.706858e-03 0.9999996
## CE:dbCAN_4:DIAMOND-GT:dbCAN_4 1.366770e-03 1.0000000
## AA:dbCAN_4:DIAMOND-GT:dbCAN_4 1.498041e-03 1.0000000
## CBM:dbCAN_4:DIAMOND-GT:dbCAN_4 1.076125e-03 1.0000000
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4 9.728442e-04 1.0000000
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4 8.895866e-04 1.0000000
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4 1.711676e-03 0.9999995
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4 1.235770e-03 1.0000000
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4 1.516114e-03 1.0000000
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4 8.967828e-04 1.0000000
## GH:CUPP-GT:dbCAN_4 8.264327e-04 1.0000000
## GT:CUPP-GT:dbCAN_4 5.573880e-04 0.9999177
## PL:CUPP-GT:dbCAN_4 1.604751e-03 1.0000000
## CE:CUPP-GT:dbCAN_4 1.091411e-03 1.0000000
## AA:CUPP-GT:dbCAN_4 1.299435e-03 1.0000000
## CBM:CUPP-GT:dbCAN_4 -7.658277e-04 0.0000000
## CE:dbCAN_4-PL:dbCAN_4 1.135924e-03 0.9999874
## AA:dbCAN_4-PL:dbCAN_4 1.427880e-03 1.0000000
## CBM:dbCAN_4-PL:dbCAN_4 9.129858e-04 0.9999947
## GH:dbCAN_4:HMMER-PL:dbCAN_4 9.333674e-04 1.0000000
## GT:dbCAN_4:HMMER-PL:dbCAN_4 5.635266e-04 0.9494137
## PL:dbCAN_4:HMMER-PL:dbCAN_4 1.630959e-03 1.0000000
## CE:dbCAN_4:HMMER-PL:dbCAN_4 1.033038e-03 0.9997131
## AA:dbCAN_4:HMMER-PL:dbCAN_4 1.404395e-03 1.0000000
## CBM:dbCAN_4:HMMER-PL:dbCAN_4 2.998476e-04 0.4370459
## GH:dbCAN_4:DIAMOND-PL:dbCAN_4 1.109169e-03 1.0000000
## GT:dbCAN_4:DIAMOND-PL:dbCAN_4 1.063324e-03 1.0000000
## PL:dbCAN_4:DIAMOND-PL:dbCAN_4 1.631556e-03 1.0000000
## CE:dbCAN_4:DIAMOND-PL:dbCAN_4 1.261891e-03 0.9999998
## AA:dbCAN_4:DIAMOND-PL:dbCAN_4 1.387245e-03 1.0000000
## CBM:dbCAN_4:DIAMOND-PL:dbCAN_4 1.080381e-03 1.0000000
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4 1.038459e-03 1.0000000
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4 9.186093e-04 0.9999994
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4 1.636373e-03 1.0000000
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4 1.136482e-03 0.9999876
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4 1.405318e-03 1.0000000
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4 9.025026e-04 0.9999914
## GH:CUPP-PL:dbCAN_4 8.909113e-04 0.9999998
## GT:CUPP-PL:dbCAN_4 5.854620e-04 0.9632725
## PL:CUPP-PL:dbCAN_4 1.529448e-03 1.0000000
## CE:CUPP-PL:dbCAN_4 9.865315e-04 0.9987064
## AA:CUPP-PL:dbCAN_4 1.188639e-03 0.9999921
## CBM:CUPP-PL:dbCAN_4 -7.615724e-04 0.0000027
## AA:dbCAN_4-CE:dbCAN_4 2.132388e-03 1.0000000
## CBM:dbCAN_4-CE:dbCAN_4 1.646470e-03 1.0000000
## GH:dbCAN_4:HMMER-CE:dbCAN_4 1.678498e-03 1.0000000
## GT:dbCAN_4:HMMER-CE:dbCAN_4 1.301957e-03 1.0000000
## PL:dbCAN_4:HMMER-CE:dbCAN_4 2.345220e-03 0.9999874
## CE:dbCAN_4:HMMER-CE:dbCAN_4 1.740797e-03 1.0000000
## AA:dbCAN_4:HMMER-CE:dbCAN_4 2.108903e-03 1.0000000
## CBM:dbCAN_4:HMMER-CE:dbCAN_4 1.033332e-03 0.9999989
## GH:dbCAN_4:DIAMOND-CE:dbCAN_4 1.854034e-03 0.9999938
## GT:dbCAN_4:DIAMOND-CE:dbCAN_4 1.801571e-03 1.0000000
## PL:dbCAN_4:DIAMOND-CE:dbCAN_4 2.345817e-03 0.9999871
## CE:dbCAN_4:DIAMOND-CE:dbCAN_4 1.968081e-03 1.0000000
## AA:dbCAN_4:DIAMOND-CE:dbCAN_4 2.091753e-03 1.0000000
## CBM:dbCAN_4:DIAMOND-CE:dbCAN_4 1.813554e-03 1.0000000
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4 1.783524e-03 0.9999998
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4 1.656856e-03 1.0000000
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4 2.350635e-03 0.9999848
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4 1.844241e-03 1.0000000
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4 2.109826e-03 1.0000000
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4 1.635987e-03 1.0000000
## GH:CUPP-CE:dbCAN_4 1.635777e-03 1.0000000
## GT:CUPP-CE:dbCAN_4 1.323521e-03 1.0000000
## PL:CUPP-CE:dbCAN_4 2.243710e-03 0.9999998
## CE:CUPP-CE:dbCAN_4 1.692722e-03 1.0000000
## AA:CUPP-CE:dbCAN_4 1.893147e-03 1.0000000
## CBM:CUPP-CE:dbCAN_4 -2.839874e-05 0.0391861
## CBM:dbCAN_4-AA:dbCAN_4 1.483787e-03 1.0000000
## GH:dbCAN_4:HMMER-AA:dbCAN_4 1.521191e-03 1.0000000
## GT:dbCAN_4:HMMER-AA:dbCAN_4 1.141580e-03 1.0000000
## PL:dbCAN_4:HMMER-AA:dbCAN_4 2.173250e-03 1.0000000
## CE:dbCAN_4:HMMER-AA:dbCAN_4 1.565576e-03 1.0000000
## AA:dbCAN_4:HMMER-AA:dbCAN_4 1.932036e-03 1.0000000
## CBM:dbCAN_4:HMMER-AA:dbCAN_4 8.706483e-04 0.9985843
## GH:dbCAN_4:DIAMOND-AA:dbCAN_4 1.696607e-03 1.0000000
## GT:dbCAN_4:DIAMOND-AA:dbCAN_4 1.641109e-03 1.0000000
## PL:dbCAN_4:DIAMOND-AA:dbCAN_4 2.173848e-03 1.0000000
## CE:dbCAN_4:DIAMOND-AA:dbCAN_4 1.792068e-03 1.0000000
## AA:dbCAN_4:DIAMOND-AA:dbCAN_4 1.914887e-03 1.0000000
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4 1.650725e-03 1.0000000
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4 1.626188e-03 1.0000000
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4 1.496395e-03 1.0000000
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4 2.178665e-03 1.0000000
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4 1.669020e-03 1.0000000
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4 1.932959e-03 1.0000000
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4 1.473303e-03 1.0000000
## GH:CUPP-AA:dbCAN_4 1.478350e-03 1.0000000
## GT:CUPP-AA:dbCAN_4 1.162973e-03 1.0000000
## PL:CUPP-AA:dbCAN_4 2.071740e-03 1.0000000
## CE:CUPP-AA:dbCAN_4 1.516708e-03 1.0000000
## AA:CUPP-AA:dbCAN_4 1.716280e-03 1.0000000
## CBM:CUPP-AA:dbCAN_4 -1.912281e-04 0.0091337
## GH:dbCAN_4:HMMER-CBM:dbCAN_4 1.020565e-03 1.0000000
## GT:dbCAN_4:HMMER-CBM:dbCAN_4 6.774390e-04 0.9999994
## PL:dbCAN_4:HMMER-CBM:dbCAN_4 1.826593e-03 0.9999947
## CE:dbCAN_4:HMMER-CBM:dbCAN_4 1.247895e-03 1.0000000
## AA:dbCAN_4:HMMER-CBM:dbCAN_4 1.628539e-03 1.0000000
## CBM:dbCAN_4:HMMER-CBM:dbCAN_4 4.321318e-04 0.9320562
## GH:dbCAN_4:DIAMOND-CBM:dbCAN_4 1.197466e-03 0.9999701
## GT:dbCAN_4:DIAMOND-CBM:dbCAN_4 1.177936e-03 1.0000000
## PL:dbCAN_4:DIAMOND-CBM:dbCAN_4 1.827190e-03 0.9999946
## CE:dbCAN_4:DIAMOND-CBM:dbCAN_4 1.481255e-03 1.0000000
## AA:dbCAN_4:DIAMOND-CBM:dbCAN_4 1.611389e-03 1.0000000
## CBM:dbCAN_4:DIAMOND-CBM:dbCAN_4 1.213784e-03 1.0000000
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 1.125926e-03 0.9999998
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 1.033222e-03 1.0000000
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 1.832008e-03 0.9999932
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 1.351339e-03 1.0000000
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 1.629462e-03 1.0000000
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4 1.034787e-03 1.0000000
## GH:CUPP-CBM:dbCAN_4 9.792091e-04 1.0000000
## GT:CUPP-CBM:dbCAN_4 7.007882e-04 0.9999999
## PL:CUPP-CBM:dbCAN_4 1.725083e-03 1.0000000
## CE:CUPP-CBM:dbCAN_4 1.205896e-03 1.0000000
## AA:CUPP-CBM:dbCAN_4 1.412783e-03 1.0000000
## CBM:CUPP-CBM:dbCAN_4 -6.281685e-04 0.0000010
## GT:dbCAN_4:HMMER-GH:dbCAN_4:HMMER 3.466627e-04 0.9608985
## PL:dbCAN_4:HMMER-GH:dbCAN_4:HMMER 1.556713e-03 1.0000000
## CE:dbCAN_4:HMMER-GH:dbCAN_4:HMMER 9.896616e-04 0.9999998
## AA:dbCAN_4:HMMER-GH:dbCAN_4:HMMER 1.375682e-03 1.0000000
## CBM:dbCAN_4:HMMER-GH:dbCAN_4:HMMER 1.171651e-04 0.2196818
## GH:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 8.415420e-04 1.0000000
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 8.477926e-04 1.0000000
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 1.557311e-03 1.0000000
## CE:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 1.225650e-03 1.0000000
## AA:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 1.358532e-03 1.0000000
## CBM:dbCAN_4:DIAMOND-GH:dbCAN_4:HMMER 8.997321e-04 1.0000000
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 7.691122e-04 1.0000000
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 7.030777e-04 1.0000000
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 1.562128e-03 1.0000000
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 1.093106e-03 1.0000000
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 1.376604e-03 1.0000000
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4:HMMER 7.198201e-04 1.0000000
## GH:CUPP-GH:dbCAN_4:HMMER 6.232849e-04 1.0000000
## GT:CUPP-GH:dbCAN_4:HMMER 3.712869e-04 0.9791685
## PL:CUPP-GH:dbCAN_4:HMMER 1.455203e-03 1.0000000
## CE:CUPP-GH:dbCAN_4:HMMER 9.502907e-04 0.9999954
## AA:CUPP-GH:dbCAN_4:HMMER 1.159925e-03 1.0000000
## CBM:CUPP-GH:dbCAN_4:HMMER -9.422209e-04 0.0000000
## PL:dbCAN_4:HMMER-GT:dbCAN_4:HMMER 2.065037e-03 0.9494589
## CE:dbCAN_4:HMMER-GT:dbCAN_4:HMMER 1.491285e-03 1.0000000
## AA:dbCAN_4:HMMER-GT:dbCAN_4:HMMER 1.874236e-03 1.0000000
## CBM:dbCAN_4:HMMER-GT:dbCAN_4:HMMER 6.522042e-04 0.9999962
## GH:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 1.402151e-03 0.4549287
## GT:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 1.392147e-03 0.9626963
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 2.065634e-03 0.9489971
## CE:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 1.725771e-03 1.0000000
## AA:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 1.857086e-03 1.0000000
## CBM:dbCAN_4:DIAMOND-GT:dbCAN_4:HMMER 1.434216e-03 0.9966415
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 1.330292e-03 0.7120363
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 1.247432e-03 0.9998345
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 2.070452e-03 0.9451588
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 1.594729e-03 1.0000000
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 1.875158e-03 1.0000000
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4:HMMER 1.254859e-03 0.9999997
## GH:CUPP-GT:dbCAN_4:HMMER 1.183894e-03 0.9913451
## GT:CUPP-GT:dbCAN_4:HMMER 9.152433e-04 1.0000000
## PL:CUPP-GT:dbCAN_4:HMMER 1.963527e-03 0.9925029
## CE:CUPP-GT:dbCAN_4:HMMER 1.450412e-03 1.0000000
## AA:CUPP-GT:dbCAN_4:HMMER 1.658479e-03 1.0000000
## CBM:CUPP-GT:dbCAN_4:HMMER -4.077373e-04 0.0000484
## CE:dbCAN_4:HMMER-PL:dbCAN_4:HMMER 1.033096e-03 0.9997136
## AA:dbCAN_4:HMMER-PL:dbCAN_4:HMMER 1.404454e-03 1.0000000
## CBM:dbCAN_4:HMMER-PL:dbCAN_4:HMMER 2.999063e-04 0.4371734
## GH:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 1.109227e-03 1.0000000
## GT:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 1.063383e-03 1.0000000
## PL:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 1.631615e-03 1.0000000
## CE:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 1.261950e-03 0.9999998
## AA:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 1.387304e-03 1.0000000
## CBM:dbCAN_4:DIAMOND-PL:dbCAN_4:HMMER 1.080439e-03 1.0000000
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 1.038517e-03 1.0000000
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 9.186679e-04 0.9999994
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 1.636432e-03 1.0000000
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 1.136541e-03 0.9999876
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 1.405377e-03 1.0000000
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4:HMMER 9.025612e-04 0.9999914
## GH:CUPP-PL:dbCAN_4:HMMER 8.909700e-04 0.9999998
## GT:CUPP-PL:dbCAN_4:HMMER 5.855206e-04 0.9633080
## PL:CUPP-PL:dbCAN_4:HMMER 1.529507e-03 1.0000000
## CE:CUPP-PL:dbCAN_4:HMMER 9.865902e-04 0.9987080
## AA:CUPP-PL:dbCAN_4:HMMER 1.188698e-03 0.9999921
## CBM:CUPP-PL:dbCAN_4:HMMER -7.615137e-04 0.0000027
## AA:dbCAN_4:HMMER-CE:dbCAN_4:HMMER 2.211789e-03 1.0000000
## CBM:dbCAN_4:HMMER-CE:dbCAN_4:HMMER 1.136218e-03 1.0000000
## GH:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 1.956920e-03 0.9996637
## GT:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 1.904457e-03 0.9999986
## PL:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 2.448703e-03 0.9997091
## CE:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 2.070967e-03 1.0000000
## AA:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 2.194639e-03 1.0000000
## CBM:dbCAN_4:DIAMOND-CE:dbCAN_4:HMMER 1.916440e-03 0.9999999
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 1.886410e-03 0.9999720
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 1.759742e-03 1.0000000
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 2.453521e-03 0.9996701
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 1.947127e-03 1.0000000
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 2.212712e-03 1.0000000
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4:HMMER 1.738873e-03 1.0000000
## GH:CUPP-CE:dbCAN_4:HMMER 1.738663e-03 1.0000000
## GT:CUPP-CE:dbCAN_4:HMMER 1.426407e-03 1.0000000
## PL:CUPP-CE:dbCAN_4:HMMER 2.346596e-03 0.9999868
## CE:CUPP-CE:dbCAN_4:HMMER 1.795608e-03 1.0000000
## AA:CUPP-CE:dbCAN_4:HMMER 1.996033e-03 1.0000000
## CBM:CUPP-CE:dbCAN_4:HMMER 7.448732e-05 0.0911399
## CBM:dbCAN_4:HMMER-AA:dbCAN_4:HMMER 8.941331e-04 0.9992163
## GH:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 1.720092e-03 1.0000000
## GT:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 1.664594e-03 1.0000000
## PL:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 2.197332e-03 1.0000000
## CE:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 1.815552e-03 1.0000000
## AA:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 1.938371e-03 1.0000000
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4:HMMER 1.674210e-03 1.0000000
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 1.649672e-03 1.0000000
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 1.519879e-03 1.0000000
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 2.202150e-03 1.0000000
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 1.692505e-03 1.0000000
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 1.956444e-03 1.0000000
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:HMMER 1.496788e-03 1.0000000
## GH:CUPP-AA:dbCAN_4:HMMER 1.501835e-03 1.0000000
## GT:CUPP-AA:dbCAN_4:HMMER 1.186458e-03 1.0000000
## PL:CUPP-AA:dbCAN_4:HMMER 2.095225e-03 1.0000000
## CE:CUPP-AA:dbCAN_4:HMMER 1.540193e-03 1.0000000
## AA:CUPP-AA:dbCAN_4:HMMER 1.739765e-03 1.0000000
## CBM:CUPP-AA:dbCAN_4:HMMER -1.677434e-04 0.0114366
## GH:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 1.810604e-03 0.0226272
## GT:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 1.791075e-03 0.2806591
## PL:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 2.440329e-03 0.4358758
## CE:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 2.094394e-03 0.9999597
## AA:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 2.224527e-03 0.9995050
## CBM:dbCAN_4:DIAMOND-CBM:dbCAN_4:HMMER 1.826923e-03 0.5635668
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 1.739064e-03 0.0607273
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 1.646360e-03 0.7139715
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 2.445146e-03 0.4254591
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 1.964477e-03 0.9999989
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 2.242600e-03 0.9991972
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:HMMER 1.647925e-03 0.9438131
## GH:CUPP-CBM:dbCAN_4:HMMER 1.592347e-03 0.3510512
## GT:CUPP-CBM:dbCAN_4:HMMER 1.313926e-03 0.9999890
## PL:CUPP-CBM:dbCAN_4:HMMER 2.338221e-03 0.6648412
## CE:CUPP-CBM:dbCAN_4:HMMER 1.819034e-03 1.0000000
## AA:CUPP-CBM:dbCAN_4:HMMER 2.025921e-03 0.9999997
## CBM:CUPP-CBM:dbCAN_4:HMMER -1.503026e-05 0.0416065
## GT:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND 6.787290e-04 1.0000000
## PL:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND 1.386742e-03 1.0000000
## CE:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND 1.054758e-03 1.0000000
## AA:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND 1.187578e-03 1.0000000
## CBM:dbCAN_4:DIAMOND-GH:dbCAN_4:DIAMOND 7.302399e-04 1.0000000
## GH:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 6.008148e-04 1.0000000
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 5.340141e-04 0.9999966
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 1.391559e-03 1.0000000
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 9.222723e-04 0.9999940
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 1.205651e-03 1.0000000
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4:DIAMOND 5.503517e-04 0.9999425
## GH:CUPP-GH:dbCAN_4:DIAMOND 4.549606e-04 0.9999971
## GT:CUPP-GH:dbCAN_4:DIAMOND 2.022057e-04 0.5441147
## PL:CUPP-GH:dbCAN_4:DIAMOND 1.284634e-03 1.0000000
## CE:CUPP-GH:dbCAN_4:DIAMOND 7.793981e-04 0.9981090
## AA:CUPP-GH:dbCAN_4:DIAMOND 9.889717e-04 0.9999972
## CBM:CUPP-GH:dbCAN_4:DIAMOND -1.111713e-03 0.0000000
## PL:dbCAN_4:DIAMOND-GT:dbCAN_4:DIAMOND 1.569811e-03 1.0000000
## CE:dbCAN_4:DIAMOND-GT:dbCAN_4:DIAMOND 1.229723e-03 1.0000000
## AA:dbCAN_4:DIAMOND-GT:dbCAN_4:DIAMOND 1.360994e-03 1.0000000
## CBM:dbCAN_4:DIAMOND-GT:dbCAN_4:DIAMOND 9.390784e-04 1.0000000
## GH:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 8.357973e-04 1.0000000
## GT:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 7.525397e-04 1.0000000
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 1.574629e-03 1.0000000
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 1.098723e-03 1.0000000
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 1.379067e-03 1.0000000
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4:DIAMOND 7.597359e-04 1.0000000
## GH:CUPP-GT:dbCAN_4:DIAMOND 6.893858e-04 1.0000000
## GT:CUPP-GT:dbCAN_4:DIAMOND 4.203411e-04 0.9783293
## PL:CUPP-GT:dbCAN_4:DIAMOND 1.467704e-03 1.0000000
## CE:CUPP-GT:dbCAN_4:DIAMOND 9.543638e-04 0.9999778
## AA:CUPP-GT:dbCAN_4:DIAMOND 1.162388e-03 1.0000000
## CBM:CUPP-GT:dbCAN_4:DIAMOND -9.028746e-04 0.0000000
## CE:dbCAN_4:DIAMOND-PL:dbCAN_4:DIAMOND 1.261352e-03 0.9999998
## AA:dbCAN_4:DIAMOND-PL:dbCAN_4:DIAMOND 1.386707e-03 1.0000000
## CBM:dbCAN_4:DIAMOND-PL:dbCAN_4:DIAMOND 1.079842e-03 1.0000000
## GH:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 1.037920e-03 1.0000000
## GT:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 9.180706e-04 0.9999994
## PL:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 1.635835e-03 1.0000000
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 1.135943e-03 0.9999874
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 1.404779e-03 1.0000000
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4:DIAMOND 9.019639e-04 0.9999912
## GH:CUPP-PL:dbCAN_4:DIAMOND 8.903727e-04 0.9999998
## GT:CUPP-PL:dbCAN_4:DIAMOND 5.849233e-04 0.9629450
## PL:CUPP-PL:dbCAN_4:DIAMOND 1.528910e-03 1.0000000
## CE:CUPP-PL:dbCAN_4:DIAMOND 9.859928e-04 0.9986911
## AA:CUPP-PL:dbCAN_4:DIAMOND 1.188100e-03 0.9999919
## CBM:CUPP-PL:dbCAN_4:DIAMOND -7.621110e-04 0.0000027
## AA:dbCAN_4:DIAMOND-CE:dbCAN_4:DIAMOND 2.020395e-03 1.0000000
## CBM:dbCAN_4:DIAMOND-CE:dbCAN_4:DIAMOND 1.748994e-03 1.0000000
## GH:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 1.721649e-03 1.0000000
## GT:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 1.593451e-03 1.0000000
## PL:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 2.281638e-03 0.9999998
## CE:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 1.773676e-03 1.0000000
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 2.038468e-03 1.0000000
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4:DIAMOND 1.571497e-03 1.0000000
## GH:CUPP-CE:dbCAN_4:DIAMOND 1.573857e-03 1.0000000
## GT:CUPP-CE:dbCAN_4:DIAMOND 1.260074e-03 1.0000000
## PL:CUPP-CE:dbCAN_4:DIAMOND 2.174713e-03 1.0000000
## CE:CUPP-CE:dbCAN_4:DIAMOND 1.621774e-03 1.0000000
## AA:CUPP-CE:dbCAN_4:DIAMOND 1.821789e-03 1.0000000
## CBM:CUPP-CE:dbCAN_4:DIAMOND -9.295927e-05 0.0222908
## CBM:dbCAN_4:DIAMOND-AA:dbCAN_4:DIAMOND 1.691359e-03 1.0000000
## GH:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 1.666822e-03 1.0000000
## GT:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 1.537029e-03 1.0000000
## PL:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 2.219300e-03 1.0000000
## CE:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 1.709655e-03 1.0000000
## AA:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 1.973594e-03 1.0000000
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:DIAMOND 1.513938e-03 1.0000000
## GH:CUPP-AA:dbCAN_4:DIAMOND 1.518984e-03 1.0000000
## GT:CUPP-AA:dbCAN_4:DIAMOND 1.203607e-03 1.0000000
## PL:CUPP-AA:dbCAN_4:DIAMOND 2.112375e-03 1.0000000
## CE:CUPP-AA:dbCAN_4:DIAMOND 1.557343e-03 1.0000000
## AA:CUPP-AA:dbCAN_4:DIAMOND 1.756915e-03 1.0000000
## CBM:CUPP-AA:dbCAN_4:DIAMOND -1.505936e-04 0.0134408
## GH:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 9.678007e-04 1.0000000
## GT:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 8.745327e-04 1.0000000
## PL:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 1.671855e-03 1.0000000
## CE:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 1.190875e-03 1.0000000
## AA:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 1.468852e-03 1.0000000
## CBM:dbCAN_4:dbCAN-sub-CBM:dbCAN_4:DIAMOND 8.757532e-04 1.0000000
## GH:CUPP-CBM:dbCAN_4:DIAMOND 8.210660e-04 1.0000000
## GT:CUPP-CBM:dbCAN_4:DIAMOND 5.420851e-04 0.9984014
## PL:CUPP-CBM:dbCAN_4:DIAMOND 1.564930e-03 1.0000000
## CE:CUPP-CBM:dbCAN_4:DIAMOND 1.045361e-03 0.9999980
## AA:CUPP-CBM:dbCAN_4:DIAMOND 1.252173e-03 1.0000000
## CBM:CUPP-CBM:dbCAN_4:DIAMOND -7.872233e-04 0.0000000
## GT:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub 5.996368e-04 1.0000000
## PL:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub 1.458318e-03 1.0000000
## CE:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub 9.892306e-04 0.9999998
## AA:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub 1.272700e-03 1.0000000
## CBM:dbCAN_4:dbCAN-sub-GH:dbCAN_4:dbCAN-sub 6.162797e-04 0.9999996
## GH:CUPP-GH:dbCAN_4:dbCAN-sub 5.200261e-04 1.0000000
## GT:CUPP-GH:dbCAN_4:dbCAN-sub 2.678417e-04 0.7885631
## PL:CUPP-GH:dbCAN_4:dbCAN-sub 1.351393e-03 1.0000000
## CE:CUPP-GH:dbCAN_4:dbCAN-sub 8.464008e-04 0.9997365
## AA:CUPP-GH:dbCAN_4:dbCAN-sub 1.056021e-03 0.9999999
## CBM:CUPP-GH:dbCAN_4:dbCAN-sub -1.045767e-03 0.0000000
## PL:dbCAN_4:dbCAN-sub-GT:dbCAN_4:dbCAN-sub 1.719344e-03 0.9999992
## CE:dbCAN_4:dbCAN-sub-GT:dbCAN_4:dbCAN-sub 1.243438e-03 1.0000000
## AA:dbCAN_4:dbCAN-sub-GT:dbCAN_4:dbCAN-sub 1.523782e-03 1.0000000
## CBM:dbCAN_4:dbCAN-sub-GT:dbCAN_4:dbCAN-sub 9.044508e-04 1.0000000
## GH:CUPP-GT:dbCAN_4:dbCAN-sub 8.341007e-04 1.0000000
## GT:CUPP-GT:dbCAN_4:dbCAN-sub 5.650560e-04 0.9999474
## PL:CUPP-GT:dbCAN_4:dbCAN-sub 1.612419e-03 1.0000000
## CE:CUPP-GT:dbCAN_4:dbCAN-sub 1.099079e-03 1.0000000
## AA:CUPP-GT:dbCAN_4:dbCAN-sub 1.307103e-03 1.0000000
## CBM:CUPP-GT:dbCAN_4:dbCAN-sub -7.581597e-04 0.0000000
## CE:dbCAN_4:dbCAN-sub-PL:dbCAN_4:dbCAN-sub 1.131126e-03 0.9999851
## AA:dbCAN_4:dbCAN-sub-PL:dbCAN_4:dbCAN-sub 1.399962e-03 1.0000000
## CBM:dbCAN_4:dbCAN-sub-PL:dbCAN_4:dbCAN-sub 8.971464e-04 0.9999890
## GH:CUPP-PL:dbCAN_4:dbCAN-sub 8.855552e-04 0.9999998
## GT:CUPP-PL:dbCAN_4:dbCAN-sub 5.801058e-04 0.9599173
## PL:CUPP-PL:dbCAN_4:dbCAN-sub 1.524092e-03 1.0000000
## CE:CUPP-PL:dbCAN_4:dbCAN-sub 9.811753e-04 0.9985477
## AA:CUPP-PL:dbCAN_4:dbCAN-sub 1.183283e-03 0.9999904
## CBM:CUPP-PL:dbCAN_4:dbCAN-sub -7.669285e-04 0.0000025
## AA:dbCAN_4:dbCAN-sub-CE:dbCAN_4:dbCAN-sub 2.109268e-03 1.0000000
## CBM:dbCAN_4:dbCAN-sub-CE:dbCAN_4:dbCAN-sub 1.635428e-03 1.0000000
## GH:CUPP-CE:dbCAN_4:dbCAN-sub 1.635219e-03 1.0000000
## GT:CUPP-CE:dbCAN_4:dbCAN-sub 1.322963e-03 1.0000000
## PL:CUPP-CE:dbCAN_4:dbCAN-sub 2.243151e-03 0.9999998
## CE:CUPP-CE:dbCAN_4:dbCAN-sub 1.692163e-03 1.0000000
## AA:CUPP-CE:dbCAN_4:dbCAN-sub 1.892589e-03 1.0000000
## CBM:CUPP-CE:dbCAN_4:dbCAN-sub -2.895716e-05 0.0389957
## CBM:dbCAN_4:dbCAN-sub-AA:dbCAN_4:dbCAN-sub 1.495865e-03 1.0000000
## GH:CUPP-AA:dbCAN_4:dbCAN-sub 1.500912e-03 1.0000000
## GT:CUPP-AA:dbCAN_4:dbCAN-sub 1.185535e-03 1.0000000
## PL:CUPP-AA:dbCAN_4:dbCAN-sub 2.094302e-03 1.0000000
## CE:CUPP-AA:dbCAN_4:dbCAN-sub 1.539270e-03 1.0000000
## AA:CUPP-AA:dbCAN_4:dbCAN-sub 1.738842e-03 1.0000000
## CBM:CUPP-AA:dbCAN_4:dbCAN-sub -1.686663e-04 0.0113369
## GH:CUPP-CBM:dbCAN_4:dbCAN-sub 9.896923e-04 1.0000000
## GT:CUPP-CBM:dbCAN_4:dbCAN-sub 7.112714e-04 1.0000000
## PL:CUPP-CBM:dbCAN_4:dbCAN-sub 1.735566e-03 1.0000000
## CE:CUPP-CBM:dbCAN_4:dbCAN-sub 1.216379e-03 1.0000000
## AA:CUPP-CBM:dbCAN_4:dbCAN-sub 1.423266e-03 1.0000000
## CBM:CUPP-CBM:dbCAN_4:dbCAN-sub -6.176852e-04 0.0000013
## GT:CUPP-GH:CUPP 4.204629e-04 0.9962343
## PL:CUPP-GH:CUPP 1.502891e-03 1.0000000
## CE:CUPP-GH:CUPP 9.976553e-04 0.9999995
## AA:CUPP-GH:CUPP 1.207229e-03 1.0000000
## CBM:CUPP-GH:CUPP -8.934558e-04 0.0000000
## PL:CUPP-GT:CUPP 1.949640e-03 0.9953081
## CE:CUPP-GT:CUPP 1.436070e-03 1.0000000
## AA:CUPP-GT:CUPP 1.644050e-03 1.0000000
## CBM:CUPP-GT:CUPP -4.202384e-04 0.0000393
## CE:CUPP-PL:CUPP 1.088100e-03 0.9998985
## AA:CUPP-PL:CUPP 1.290208e-03 0.9999999
## CBM:CUPP-PL:CUPP -6.600035e-04 0.0000133
## AA:CUPP-CE:CUPP 2.097149e-03 1.0000000
## CBM:CUPP-CE:CUPP 1.824003e-04 0.1904320
## CBM:CUPP-AA:CUPP 4.801275e-05 0.072879310.3 CAZy family sensitivity against specificity
For better resolution we can group the CAZy families by their parent CAzy classes, and compare the performances of the tools CAZy class, by CAZy class. Owing to the minimal variation in specificity scores, specificity was plotted as the percentage specificity log10.
10.3.1 Glycoside Hydrolases
Figure 10.13 shows the plotting of sensitivity against specificity for each Glycoside Hydrolase CAZy family.
Figure 10.13: Scatter plot of recall (sensitivity) against specificity for predicting each CAZy family for each CAZyme classifier in the CAZy class Glycoside Hydrolases. Each GH CAZy family is represented as a single point on the plot.
10.3.2 Glycosyltransferases
Figure 10.14 shows the plotting of sensitivity against specificity for each Glycosyltransferases CAZy family.
Figure 10.14: Scatter plot of recall (sensitivity) against specificity for predicting each CAZy family for each CAZyme classifier in the CAZy class Glycosyltransferases. Each GT CAZy family is represented as a single point on the plot.
10.3.3 Polysaccharide Lyases
Figure 10.13 shows the plotting of sensitivity against specificity for each Polysaccharide Lyases CAZy family.
Figure 10.15: Scatter plot of recall (sensitivity) against specificity for predicting each CAZy family for each CAZyme classifier in the CAZy class Polysaccharide Lyases. Each PL CAZy family is represented as a single point on the plot.
10.3.4 Carbohydrate Esterases
Figure 10.16 shows the plotting of sensitivity against specificity for each Carbohydrate Esterases CAZy family.
Figure 10.16: Scatter plot of recall (sensitivity) against specificity for predicting each CAZy family for each CAZyme classifier in the CAZy class Carbohydrate Esterases. Each CE CAZy family is represented as a single point on the plot.
10.3.5 Auxillary Activities
The figure below shows the plotting of sensitivity against specificity for each Auxillary Activities CAZy family.
Figure 10.17: Scatter plot of recall (sensitivity) against specificity for predicting each CAZy family for each CAZyme classifier in the CAZy class Auxillary Activities. Each AA CAZy family is represented as a single point on the plot.
10.3.6 Carbohydate Binding Modules
Figure 10.18 shows the plotting of sensitivity against specificity for each Carbohydrate Binding Module CAZy family.
Figure 10.18: Scatter plot of recall (sensitivity) against specificity for predicting each CAZy family for each CAZyme classifier in the CAZy class Carbohydrate Binding Modules. Each CBM CAZy family is represented as a single point on the plot.
10.4 Consistently poor performing CAZy families
We can pull out CAZy families for which at least three of the evaluated classifiers (when including the individual tools incoporated into dbCAN) produce a sensitivity score of less than 0.75 for said CAZy family.
10.5 GH difficult families
10.6 GT difficult families
10.7 PL difficult families
10.8 CE difficult families
10.9 AA difficult families
10.10 CBM difficult families
10.11 All poor performing CAZyme families
11 Evaluation of multi-label CAZy family classification performance
CAZy annotates proteins in a domain-wise manner. Consequently, a single protein may be assigned to multiple CAZy families. The ability of a classifier to assign all the correct CAZy family annotations for a given protein when only evaluating the CAZy family classification performance per CAZy family, independently of all other CAZy classes.
Multilabel classification raises when a single instance can be assinged to multiple classes. In this evaluation a single instance is a protein and the classes are CAZy families, a single CAZyme can be assigned to multiple CAZy families. This is important to take into consideration because the same approaches for statistical evaluation of binary classification provided a limited view of the performance of the classifiers when applied to multilabel classification.
The CAZy family multi-label classification performance is represented by the Rand Index (RI) and Adjusted Rand Index (ARI). The RI is a quantitive measure of similarity between two clusterings by considering all pairs of samples and counting pairs that are assigned in the same or different clusters in the predicted and true clusterings. In this case the two clusters are the predicted and groud truth CAZy family annotations. The raw RI score is then “adjusted for chance” into the ARI score using the following scheme:
ARI = (RI - Expected_RI) / (max(RI) - Expected_RI)
This produces a score between 1 and -1. A score of 1 is produced if all predicted and known CAZy family annotations are identical, 0 if completely random clustering of -1 if systematically incorrect clustering and the number of incorrect classifications of proteins is greater than would be expected from randomly annotating proteins with CAZy families.
| Prediction_tool | Mean | Standard Deviation | Lower CI | Upper CI |
|---|---|---|---|---|
| dbCAN_4 | 0.9998 | 0.0011 | 0.9997 | 0.9998 |
| dbCAN_4:HMMER | 0.9996 | 0.0014 | 0.9996 | 0.9996 |
| dbCAN_4:DIAMOND | 0.9998 | 0.0009 | 0.9998 | 0.9998 |
| dbCAN_4:dbCAN-sub | 0.9998 | 0.0011 | 0.9997 | 0.9998 |
| CUPP | 0.9994 | 0.0015 | 0.9994 | 0.9995 |
| Prediction_tool | Mean | Standard Deviation | Lower CI | Upper CI |
|---|---|---|---|---|
| dbCAN_4 | 0.9538 | 0.2050 | 0.9507 | 0.9570 |
| dbCAN_4:HMMER | 0.9221 | 0.2598 | 0.9180 | 0.9261 |
| dbCAN_4:DIAMOND | 0.9636 | 0.1847 | 0.9608 | 0.9665 |
| dbCAN_4:dbCAN-sub | 0.9544 | 0.2032 | 0.9512 | 0.9575 |
| CUPP | 0.9012 | 0.2832 | 0.8968 | 0.9055 |
12 CAZy family taxonomic performance
12.1 Across all of CAZy
12.1.1 Specificity
| Prediction_tool | Mean | Standard Deviation | Lower CI | Upper CI | Tax_group |
|---|---|---|---|---|---|
| dbCAN_4 | 0.9999 | 3e-04 | 0.9999 | 0.9999 | All |
| dbCAN_4:HMMER | 0.9999 | 4e-04 | 0.9998 | 0.9999 | All |
| dbCAN_4:DIAMOND | 0.9999 | 3e-04 | 0.9998 | 0.9999 | All |
| dbCAN_4:dbCAN-sub | 0.9999 | 4e-04 | 0.9998 | 0.9999 | All |
| CUPP | 0.9999 | 3e-04 | 0.9999 | 1.0000 | All |
| dbCAN_4 | 0.9999 | 6e-04 | 0.9998 | 1.0000 | Bacteria |
| dbCAN_4:HMMER | 0.9999 | 5e-04 | 0.9998 | 0.9999 | Bacteria |
| dbCAN_4:DIAMOND | 0.9999 | 6e-04 | 0.9998 | 0.9999 | Bacteria |
| dbCAN_4:dbCAN-sub | 0.9998 | 6e-04 | 0.9998 | 0.9999 | Bacteria |
| CUPP | 0.9999 | 6e-04 | 0.9998 | 1.0000 | Bacteria |
| dbCAN_4 | 0.9998 | 5e-04 | 0.9997 | 0.9999 | Eukaryote |
| dbCAN_4:HMMER | 0.9998 | 6e-04 | 0.9997 | 0.9999 | Eukaryote |
| dbCAN_4:DIAMOND | 0.9997 | 6e-04 | 0.9997 | 0.9998 | Eukaryote |
| dbCAN_4:dbCAN-sub | 0.9998 | 6e-04 | 0.9997 | 0.9999 | Eukaryote |
| CUPP | 0.9998 | 5e-04 | 0.9998 | 0.9999 | Eukaryote |
12.1.2 Sensitivity
| Prediction_tool | Mean | Standard Deviation | Lower CI | Upper CI | Tax_group |
|---|---|---|---|---|---|
| dbCAN_4 | 0.9001 | 0.2615 | 0.8716 | 0.9286 | All |
| dbCAN_4:HMMER | 0.8576 | 0.2976 | 0.8253 | 0.8898 | All |
| dbCAN_4:DIAMOND | 0.9379 | 0.1941 | 0.9166 | 0.9591 | All |
| dbCAN_4:dbCAN-sub | 0.8905 | 0.2722 | 0.8609 | 0.9201 | All |
| CUPP | 0.6422 | 0.4389 | 0.5940 | 0.6904 | All |
| dbCAN_4 | 0.8866 | 0.2805 | 0.8515 | 0.9218 | Bacteria |
| dbCAN_4:HMMER | 0.8367 | 0.3218 | 0.7969 | 0.8766 | Bacteria |
| dbCAN_4:DIAMOND | 0.9170 | 0.2264 | 0.8884 | 0.9456 | Bacteria |
| dbCAN_4:dbCAN-sub | 0.8855 | 0.2805 | 0.8503 | 0.9206 | Bacteria |
| CUPP | 0.6302 | 0.4547 | 0.5728 | 0.6877 | Bacteria |
| dbCAN_4 | 0.9186 | 0.2378 | 0.8859 | 0.9512 | Eukaryote |
| dbCAN_4:HMMER | 0.8581 | 0.3004 | 0.8168 | 0.8994 | Eukaryote |
| dbCAN_4:DIAMOND | 0.9726 | 0.1110 | 0.9572 | 0.9879 | Eukaryote |
| dbCAN_4:dbCAN-sub | 0.9060 | 0.2565 | 0.8708 | 0.9411 | Eukaryote |
| CUPP | 0.7038 | 0.4122 | 0.6467 | 0.7610 | Eukaryote |
12.1.3 Precision
| Prediction_tool | Mean | Standard Deviation | Lower CI | Upper CI | Tax_group |
|---|---|---|---|---|---|
| dbCAN_4 | 0.8906 | 0.2705 | 0.8612 | 0.9201 | All |
| dbCAN_4:HMMER | 0.8695 | 0.2934 | 0.8377 | 0.9013 | All |
| dbCAN_4:DIAMOND | 0.9231 | 0.2059 | 0.9005 | 0.9457 | All |
| dbCAN_4:dbCAN-sub | 0.8811 | 0.2802 | 0.8506 | 0.9116 | All |
| CUPP | 0.6793 | 0.4519 | 0.6297 | 0.7290 | All |
| dbCAN_4 | 0.8872 | 0.2897 | 0.8509 | 0.9235 | Bacteria |
| dbCAN_4:HMMER | 0.8606 | 0.3219 | 0.8208 | 0.9005 | Bacteria |
| dbCAN_4:DIAMOND | 0.9202 | 0.2297 | 0.8911 | 0.9492 | Bacteria |
| dbCAN_4:dbCAN-sub | 0.8817 | 0.2912 | 0.8452 | 0.9182 | Bacteria |
| CUPP | 0.6595 | 0.4672 | 0.6005 | 0.7186 | Bacteria |
| dbCAN_4 | 0.9083 | 0.2388 | 0.8755 | 0.9411 | Eukaryote |
| dbCAN_4:HMMER | 0.8747 | 0.2840 | 0.8356 | 0.9137 | Eukaryote |
| dbCAN_4:DIAMOND | 0.9403 | 0.1526 | 0.9192 | 0.9615 | Eukaryote |
| dbCAN_4:dbCAN-sub | 0.8960 | 0.2557 | 0.8610 | 0.9310 | Eukaryote |
| CUPP | 0.7276 | 0.4212 | 0.6692 | 0.7861 | Eukaryote |
12.1.4 F1-score
| Prediction_tool | Mean | Standard Deviation | Lower CI | Upper CI | Tax_group |
|---|---|---|---|---|---|
| dbCAN_4 | 0.8856 | 0.2636 | 0.8569 | 0.9143 | All |
| dbCAN_4:HMMER | 0.8501 | 0.2933 | 0.8183 | 0.8819 | All |
| dbCAN_4:DIAMOND | 0.9229 | 0.1985 | 0.9012 | 0.9447 | All |
| dbCAN_4:dbCAN-sub | 0.8750 | 0.2736 | 0.8452 | 0.9047 | All |
| CUPP | 0.6511 | 0.4385 | 0.6029 | 0.6992 | All |
| dbCAN_4 | 0.8780 | 0.2819 | 0.8427 | 0.9133 | Bacteria |
| dbCAN_4:HMMER | 0.8382 | 0.3172 | 0.7989 | 0.8775 | Bacteria |
| dbCAN_4:DIAMOND | 0.9119 | 0.2237 | 0.8836 | 0.9402 | Bacteria |
| dbCAN_4:dbCAN-sub | 0.8740 | 0.2826 | 0.8386 | 0.9094 | Bacteria |
| CUPP | 0.6393 | 0.4557 | 0.5817 | 0.6969 | Bacteria |
| dbCAN_4 | 0.9040 | 0.2366 | 0.8715 | 0.9365 | Eukaryote |
| dbCAN_4:HMMER | 0.8495 | 0.2926 | 0.8093 | 0.8897 | Eukaryote |
| dbCAN_4:DIAMOND | 0.9483 | 0.1321 | 0.9300 | 0.9666 | Eukaryote |
| dbCAN_4:dbCAN-sub | 0.8914 | 0.2540 | 0.8566 | 0.9262 | Eukaryote |
| CUPP | 0.7066 | 0.4104 | 0.6496 | 0.7635 | Eukaryote |
12.1.5 Accuracy
| Prediction_tool | Mean | Standard Deviation | Lower CI | Upper CI | Tax_group |
|---|---|---|---|---|---|
| dbCAN_4 | 0.9996 | 0.0012 | 0.9995 | 0.9998 | All |
| dbCAN_4:HMMER | 0.9994 | 0.0019 | 0.9992 | 0.9996 | All |
| dbCAN_4:DIAMOND | 0.9997 | 0.0007 | 0.9997 | 0.9998 | All |
| dbCAN_4:dbCAN-sub | 0.9996 | 0.0012 | 0.9995 | 0.9998 | All |
| CUPP | 0.9992 | 0.0021 | 0.9990 | 0.9994 | All |
| dbCAN_4 | 0.9996 | 0.0013 | 0.9994 | 0.9997 | Bacteria |
| dbCAN_4:HMMER | 0.9992 | 0.0026 | 0.9989 | 0.9996 | Bacteria |
| dbCAN_4:DIAMOND | 0.9996 | 0.0012 | 0.9994 | 0.9997 | Bacteria |
| dbCAN_4:dbCAN-sub | 0.9996 | 0.0013 | 0.9994 | 0.9997 | Bacteria |
| CUPP | 0.9989 | 0.0030 | 0.9985 | 0.9993 | Bacteria |
| dbCAN_4 | 0.9994 | 0.0019 | 0.9991 | 0.9997 | Eukaryote |
| dbCAN_4:HMMER | 0.9990 | 0.0026 | 0.9987 | 0.9994 | Eukaryote |
| dbCAN_4:DIAMOND | 0.9997 | 0.0007 | 0.9996 | 0.9998 | Eukaryote |
| dbCAN_4:dbCAN-sub | 0.9994 | 0.0020 | 0.9991 | 0.9996 | Eukaryote |
| CUPP | 0.9988 | 0.0028 | 0.9984 | 0.9991 | Eukaryote |
12.2 Per CAZy class
12.2.1 Specificity
| Prediction_tool | Mean | Standard Deviation | LowerCI | UpperCI | Tax_group | CAZy_class |
|---|---|---|---|---|---|---|
| dbCAN_4 | 1.0000 | 0.0002 | 0.9999 | 1.0000 | All | GH |
| dbCAN_4:HMMER | 1.0000 | 0.0002 | 0.9999 | 1.0000 | All | GH |
| dbCAN_4:DIAMOND | 0.9999 | 0.0004 | 0.9998 | 1.0000 | All | GH |
| dbCAN_4:dbCAN-sub | 0.9999 | 0.0004 | 0.9999 | 1.0000 | All | GH |
| CUPP | 0.9999 | 0.0004 | 0.9999 | 1.0000 | All | GH |
| dbCAN_4 | 0.9999 | 0.0002 | 0.9999 | 1.0000 | Bacteria | GH |
| dbCAN_4:HMMER | 0.9999 | 0.0003 | 0.9998 | 1.0000 | Bacteria | GH |
| dbCAN_4:DIAMOND | 0.9999 | 0.0003 | 0.9998 | 0.9999 | Bacteria | GH |
| dbCAN_4:dbCAN-sub | 0.9999 | 0.0002 | 0.9999 | 1.0000 | Bacteria | GH |
| CUPP | 0.9999 | 0.0002 | 0.9999 | 1.0000 | Bacteria | GH |
| dbCAN_4 | 1.0000 | 0.0001 | 0.9999 | 1.0000 | Eukaryote | GH |
| dbCAN_4:HMMER | 0.9999 | 0.0001 | 0.9999 | 1.0000 | Eukaryote | GH |
| dbCAN_4:DIAMOND | 0.9999 | 0.0002 | 0.9999 | 1.0000 | Eukaryote | GH |
| dbCAN_4:dbCAN-sub | 0.9999 | 0.0002 | 0.9999 | 1.0000 | Eukaryote | GH |
| CUPP | 0.9999 | 0.0002 | 0.9999 | 1.0000 | Eukaryote | GH |
| dbCAN_4 | 0.9999 | 0.0004 | 0.9997 | 1.0000 | All | GT |
| dbCAN_4:HMMER | 0.9999 | 0.0002 | 0.9998 | 1.0000 | All | GT |
| dbCAN_4:DIAMOND | 0.9999 | 0.0005 | 0.9997 | 1.0000 | All | GT |
| dbCAN_4:dbCAN-sub | 0.9998 | 0.0006 | 0.9996 | 1.0000 | All | GT |
| CUPP | 0.9999 | 0.0003 | 0.9998 | 1.0000 | All | GT |
| dbCAN_4 | 0.9997 | 0.0005 | 0.9996 | 0.9999 | Bacteria | GT |
| dbCAN_4:HMMER | 0.9997 | 0.0006 | 0.9995 | 0.9999 | Bacteria | GT |
| dbCAN_4:DIAMOND | 0.9997 | 0.0006 | 0.9996 | 0.9999 | Bacteria | GT |
| dbCAN_4:dbCAN-sub | 0.9997 | 0.0005 | 0.9996 | 0.9999 | Bacteria | GT |
| CUPP | 0.9998 | 0.0004 | 0.9997 | 0.9999 | Bacteria | GT |
| dbCAN_4 | 0.9999 | 0.0003 | 0.9998 | 0.9999 | Eukaryote | GT |
| dbCAN_4:HMMER | 0.9999 | 0.0003 | 0.9998 | 0.9999 | Eukaryote | GT |
| dbCAN_4:DIAMOND | 0.9999 | 0.0003 | 0.9998 | 0.9999 | Eukaryote | GT |
| dbCAN_4:dbCAN-sub | 0.9998 | 0.0003 | 0.9998 | 0.9999 | Eukaryote | GT |
| CUPP | 0.9999 | 0.0002 | 0.9999 | 1.0000 | Eukaryote | GT |
| dbCAN_4 | 1.0000 | 0.0001 | 0.9999 | 1.0000 | All | PL |
| dbCAN_4:HMMER | 1.0000 | 0.0001 | 0.9999 | 1.0000 | All | PL |
| dbCAN_4:DIAMOND | 1.0000 | 0.0001 | 0.9999 | 1.0000 | All | PL |
| dbCAN_4:dbCAN-sub | 1.0000 | 0.0001 | 0.9999 | 1.0000 | All | PL |
| CUPP | 1.0000 | 0.0000 | 1.0000 | 1.0000 | All | PL |
| dbCAN_4 | 0.9999 | 0.0001 | 0.9998 | 1.0000 | Bacteria | PL |
| dbCAN_4:HMMER | 0.9999 | 0.0001 | 0.9998 | 1.0000 | Bacteria | PL |
| dbCAN_4:DIAMOND | 0.9999 | 0.0002 | 0.9997 | 1.0000 | Bacteria | PL |
| dbCAN_4:dbCAN-sub | 0.9999 | 0.0001 | 0.9998 | 1.0000 | Bacteria | PL |
| CUPP | 0.9999 | 0.0001 | 0.9998 | 1.0000 | Bacteria | PL |
| dbCAN_4 | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Eukaryote | PL |
| dbCAN_4:HMMER | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Eukaryote | PL |
| dbCAN_4:DIAMOND | 1.0000 | 0.0001 | 0.9999 | 1.0000 | Eukaryote | PL |
| dbCAN_4:dbCAN-sub | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Eukaryote | PL |
| CUPP | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Eukaryote | PL |
| dbCAN_4 | 0.9993 | 0.0019 | 0.9982 | 1.0003 | All | CE |
| dbCAN_4:HMMER | 0.9992 | 0.0019 | 0.9982 | 1.0003 | All | CE |
| dbCAN_4:DIAMOND | 0.9993 | 0.0017 | 0.9984 | 1.0002 | All | CE |
| dbCAN_4:dbCAN-sub | 0.9993 | 0.0019 | 0.9982 | 1.0003 | All | CE |
| CUPP | 0.9993 | 0.0019 | 0.9982 | 1.0003 | All | CE |
| dbCAN_4 | 0.9998 | 0.0004 | 0.9996 | 1.0000 | Bacteria | CE |
| dbCAN_4:HMMER | 0.9997 | 0.0004 | 0.9995 | 1.0000 | Bacteria | CE |
| dbCAN_4:DIAMOND | 0.9996 | 0.0008 | 0.9991 | 1.0001 | Bacteria | CE |
| dbCAN_4:dbCAN-sub | 0.9998 | 0.0004 | 0.9995 | 1.0000 | Bacteria | CE |
| CUPP | 0.9998 | 0.0004 | 0.9996 | 1.0001 | Bacteria | CE |
| dbCAN_4 | 0.9996 | 0.0009 | 0.9991 | 1.0000 | Eukaryote | CE |
| dbCAN_4:HMMER | 0.9996 | 0.0009 | 0.9991 | 1.0000 | Eukaryote | CE |
| dbCAN_4:DIAMOND | 0.9996 | 0.0009 | 0.9991 | 1.0000 | Eukaryote | CE |
| dbCAN_4:dbCAN-sub | 0.9996 | 0.0009 | 0.9991 | 1.0000 | Eukaryote | CE |
| CUPP | 0.9996 | 0.0009 | 0.9991 | 1.0001 | Eukaryote | CE |
| dbCAN_4 | 1.0000 | NA | NaN | NaN | All | AA |
| dbCAN_4:HMMER | 1.0000 | NA | NaN | NaN | All | AA |
| dbCAN_4:DIAMOND | 1.0000 | NA | NaN | NaN | All | AA |
| dbCAN_4:dbCAN-sub | 1.0000 | NA | NaN | NaN | All | AA |
| CUPP | 1.0000 | NA | NaN | NaN | All | AA |
| dbCAN_4 | 0.9992 | 0.0013 | 0.9985 | 1.0000 | Bacteria | AA |
| dbCAN_4:HMMER | 0.9992 | 0.0013 | 0.9985 | 0.9999 | Bacteria | AA |
| dbCAN_4:DIAMOND | 0.9992 | 0.0013 | 0.9985 | 0.9999 | Bacteria | AA |
| dbCAN_4:dbCAN-sub | 0.9992 | 0.0014 | 0.9984 | 0.9999 | Bacteria | AA |
| CUPP | 0.9993 | 0.0014 | 0.9985 | 1.0001 | Bacteria | AA |
| dbCAN_4 | 0.9996 | 0.0007 | 0.9993 | 1.0000 | Eukaryote | AA |
| dbCAN_4:HMMER | 0.9996 | 0.0007 | 0.9993 | 1.0000 | Eukaryote | AA |
| dbCAN_4:DIAMOND | 0.9996 | 0.0006 | 0.9993 | 0.9999 | Eukaryote | AA |
| dbCAN_4:dbCAN-sub | 0.9996 | 0.0007 | 0.9993 | 1.0000 | Eukaryote | AA |
| CUPP | 0.9997 | 0.0007 | 0.9993 | 1.0000 | Eukaryote | AA |
| dbCAN_4 | 0.9998 | 0.0005 | 0.9997 | 1.0000 | All | CBM |
| dbCAN_4:HMMER | 0.9998 | 0.0005 | 0.9997 | 1.0000 | All | CBM |
| dbCAN_4:DIAMOND | 0.9999 | 0.0002 | 0.9998 | 1.0000 | All | CBM |
| dbCAN_4:dbCAN-sub | 0.9998 | 0.0005 | 0.9996 | 1.0000 | All | CBM |
| CUPP | 1.0000 | 0.0000 | 1.0000 | 1.0000 | All | CBM |
| dbCAN_4 | 0.9998 | 0.0005 | 0.9996 | 1.0000 | Bacteria | CBM |
| dbCAN_4:HMMER | 0.9999 | 0.0005 | 0.9997 | 1.0001 | Bacteria | CBM |
| dbCAN_4:DIAMOND | 0.9997 | 0.0004 | 0.9996 | 0.9999 | Bacteria | CBM |
| dbCAN_4:dbCAN-sub | 0.9997 | 0.0009 | 0.9993 | 1.0001 | Bacteria | CBM |
| CUPP | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | CBM |
| dbCAN_4 | 0.9999 | 0.0004 | 0.9998 | 1.0000 | Eukaryote | CBM |
| dbCAN_4:HMMER | 0.9999 | 0.0004 | 0.9998 | 1.0000 | Eukaryote | CBM |
| dbCAN_4:DIAMOND | 0.9999 | 0.0002 | 0.9998 | 0.9999 | Eukaryote | CBM |
| dbCAN_4:dbCAN-sub | 0.9998 | 0.0005 | 0.9997 | 1.0000 | Eukaryote | CBM |
| CUPP | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Eukaryote | CBM |
12.2.2 Sensitivity
| Prediction_tool | Mean | Standard Deviation | LowerCI | UpperCI | Tax_group | CAZy_class |
|---|---|---|---|---|---|---|
| dbCAN_4 | 0.9197 | 0.2355 | 0.8799 | 0.9595 | All | GH |
| dbCAN_4:HMMER | 0.8868 | 0.2684 | 0.8418 | 0.9318 | All | GH |
| dbCAN_4:DIAMOND | 0.9489 | 0.1753 | 0.9191 | 0.9787 | All | GH |
| dbCAN_4:dbCAN-sub | 0.9096 | 0.2496 | 0.8676 | 0.9516 | All | GH |
| CUPP | 0.7845 | 0.3643 | 0.7225 | 0.8465 | All | GH |
| dbCAN_4 | 0.9037 | 0.2638 | 0.8566 | 0.9507 | Bacteria | GH |
| dbCAN_4:HMMER | 0.8759 | 0.2875 | 0.8250 | 0.9268 | Bacteria | GH |
| dbCAN_4:DIAMOND | 0.9336 | 0.2096 | 0.8959 | 0.9714 | Bacteria | GH |
| dbCAN_4:dbCAN-sub | 0.9001 | 0.2661 | 0.8526 | 0.9476 | Bacteria | GH |
| CUPP | 0.7845 | 0.3768 | 0.7167 | 0.8523 | Bacteria | GH |
| dbCAN_4 | 0.9610 | 0.1591 | 0.9273 | 0.9947 | Eukaryote | GH |
| dbCAN_4:HMMER | 0.9137 | 0.2277 | 0.8655 | 0.9620 | Eukaryote | GH |
| dbCAN_4:DIAMOND | 0.9809 | 0.0713 | 0.9658 | 0.9960 | Eukaryote | GH |
| dbCAN_4:dbCAN-sub | 0.9496 | 0.1881 | 0.9100 | 0.9892 | Eukaryote | GH |
| CUPP | 0.8280 | 0.3351 | 0.7570 | 0.8990 | Eukaryote | GH |
| dbCAN_4 | 0.9103 | 0.2389 | 0.8557 | 0.9649 | All | GT |
| dbCAN_4:HMMER | 0.8644 | 0.2718 | 0.8027 | 0.9261 | All | GT |
| dbCAN_4:DIAMOND | 0.9360 | 0.1867 | 0.8933 | 0.9787 | All | GT |
| dbCAN_4:dbCAN-sub | 0.9105 | 0.2391 | 0.8558 | 0.9651 | All | GT |
| CUPP | 0.8039 | 0.2981 | 0.7354 | 0.8725 | All | GT |
| dbCAN_4 | 0.8530 | 0.2927 | 0.7581 | 0.9478 | Bacteria | GT |
| dbCAN_4:HMMER | 0.7406 | 0.3657 | 0.6280 | 0.8531 | Bacteria | GT |
| dbCAN_4:DIAMOND | 0.8909 | 0.2160 | 0.8199 | 0.9619 | Bacteria | GT |
| dbCAN_4:dbCAN-sub | 0.8523 | 0.2927 | 0.7574 | 0.9472 | Bacteria | GT |
| CUPP | 0.7959 | 0.3361 | 0.6854 | 0.9063 | Bacteria | GT |
| dbCAN_4 | 0.9239 | 0.2370 | 0.8598 | 0.9880 | Eukaryote | GT |
| dbCAN_4:HMMER | 0.8776 | 0.2613 | 0.8070 | 0.9483 | Eukaryote | GT |
| dbCAN_4:DIAMOND | 0.9652 | 0.1518 | 0.9241 | 1.0062 | Eukaryote | GT |
| dbCAN_4:dbCAN-sub | 0.9247 | 0.2372 | 0.8606 | 0.9888 | Eukaryote | GT |
| CUPP | 0.8048 | 0.2757 | 0.7295 | 0.8800 | Eukaryote | GT |
| dbCAN_4 | 0.9232 | 0.2313 | 0.8232 | 1.0233 | All | PL |
| dbCAN_4:HMMER | 0.9232 | 0.2313 | 0.8232 | 1.0233 | All | PL |
| dbCAN_4:DIAMOND | 0.9776 | 0.1042 | 0.9325 | 1.0226 | All | PL |
| dbCAN_4:dbCAN-sub | 0.9239 | 0.2315 | 0.8238 | 1.0240 | All | PL |
| CUPP | 0.7051 | 0.4164 | 0.5251 | 0.8852 | All | PL |
| dbCAN_4 | 0.9195 | 0.2361 | 0.8148 | 1.0241 | Bacteria | PL |
| dbCAN_4:HMMER | 0.9195 | 0.2361 | 0.8148 | 1.0241 | Bacteria | PL |
| dbCAN_4:DIAMOND | 0.9763 | 0.1065 | 0.9291 | 1.0235 | Bacteria | PL |
| dbCAN_4:dbCAN-sub | 0.9205 | 0.2364 | 0.8157 | 1.0253 | Bacteria | PL |
| CUPP | 0.6912 | 0.4207 | 0.5047 | 0.8777 | Bacteria | PL |
| dbCAN_4 | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Eukaryote | PL |
| dbCAN_4:HMMER | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Eukaryote | PL |
| dbCAN_4:DIAMOND | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Eukaryote | PL |
| dbCAN_4:dbCAN-sub | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Eukaryote | PL |
| CUPP | 0.7500 | 0.4629 | 0.3630 | 1.1370 | Eukaryote | PL |
| dbCAN_4 | 0.8773 | 0.3199 | 0.7182 | 1.0364 | All | CE |
| dbCAN_4:HMMER | 0.8670 | 0.3173 | 0.7091 | 1.0248 | All | CE |
| dbCAN_4:DIAMOND | 0.9706 | 0.0472 | 0.9463 | 0.9949 | All | CE |
| dbCAN_4:dbCAN-sub | 0.8787 | 0.3204 | 0.7193 | 1.0380 | All | CE |
| CUPP | 0.7414 | 0.4256 | 0.5226 | 0.9602 | All | CE |
| dbCAN_4 | 0.9213 | 0.2560 | 0.7796 | 1.0631 | Bacteria | CE |
| dbCAN_4:HMMER | 0.9122 | 0.2560 | 0.7705 | 1.0540 | Bacteria | CE |
| dbCAN_4:DIAMOND | 0.9562 | 0.0802 | 0.9118 | 1.0006 | Bacteria | CE |
| dbCAN_4:dbCAN-sub | 0.9213 | 0.2560 | 0.7796 | 1.0631 | Bacteria | CE |
| CUPP | 0.7847 | 0.4074 | 0.5591 | 1.0103 | Bacteria | CE |
| dbCAN_4 | 0.7919 | 0.4106 | 0.5646 | 1.0193 | Eukaryote | CE |
| dbCAN_4:HMMER | 0.7798 | 0.4066 | 0.5546 | 1.0050 | Eukaryote | CE |
| dbCAN_4:DIAMOND | 0.9729 | 0.0664 | 0.9328 | 1.0130 | Eukaryote | CE |
| dbCAN_4:dbCAN-sub | 0.7939 | 0.4116 | 0.5660 | 1.0219 | Eukaryote | CE |
| CUPP | 0.7500 | 0.4294 | 0.4905 | 1.0094 | Eukaryote | CE |
| dbCAN_4 | 0.9102 | 0.2570 | 0.7732 | 1.0471 | All | AA |
| dbCAN_4:HMMER | 0.9085 | 0.2565 | 0.7718 | 1.0452 | All | AA |
| dbCAN_4:DIAMOND | 0.9567 | 0.1038 | 0.9014 | 1.0120 | All | AA |
| dbCAN_4:dbCAN-sub | 0.9093 | 0.2567 | 0.7725 | 1.0461 | All | AA |
| CUPP | 0.6941 | 0.4385 | 0.4604 | 0.9277 | All | AA |
| dbCAN_4 | 1.0000 | NA | NaN | NaN | Bacteria | AA |
| dbCAN_4:HMMER | 1.0000 | NA | NaN | NaN | Bacteria | AA |
| dbCAN_4:DIAMOND | 0.9375 | NA | NaN | NaN | Bacteria | AA |
| dbCAN_4:dbCAN-sub | 1.0000 | NA | NaN | NaN | Bacteria | AA |
| CUPP | 1.0000 | NA | NaN | NaN | Bacteria | AA |
| dbCAN_4 | 0.9042 | 0.2648 | 0.7575 | 1.0508 | Eukaryote | AA |
| dbCAN_4:HMMER | 0.9024 | 0.2643 | 0.7560 | 1.0488 | Eukaryote | AA |
| dbCAN_4:DIAMOND | 0.9580 | 0.1073 | 0.8986 | 1.0174 | Eukaryote | AA |
| dbCAN_4:dbCAN-sub | 0.9033 | 0.2645 | 0.7568 | 1.0498 | Eukaryote | AA |
| CUPP | 0.6737 | 0.4459 | 0.4267 | 0.9207 | Eukaryote | AA |
| dbCAN_4 | 0.8332 | 0.3345 | 0.7436 | 0.9228 | All | CBM |
| dbCAN_4:HMMER | 0.7311 | 0.3923 | 0.6261 | 0.8362 | All | CBM |
| dbCAN_4:DIAMOND | 0.8811 | 0.2943 | 0.8016 | 0.9607 | All | CBM |
| dbCAN_4:dbCAN-sub | 0.8012 | 0.3530 | 0.7066 | 0.8957 | All | CBM |
| CUPP | 0.0000 | 0.0000 | 0.0000 | 0.0000 | All | CBM |
| dbCAN_4 | 0.8413 | 0.3390 | 0.7417 | 0.9408 | Bacteria | CBM |
| dbCAN_4:HMMER | 0.7543 | 0.3894 | 0.6400 | 0.8687 | Bacteria | CBM |
| dbCAN_4:DIAMOND | 0.8531 | 0.3242 | 0.7569 | 0.9494 | Bacteria | CBM |
| dbCAN_4:dbCAN-sub | 0.8445 | 0.3353 | 0.7461 | 0.9429 | Bacteria | CBM |
| CUPP | 0.0000 | 0.0000 | 0.0000 | 0.0000 | Bacteria | CBM |
| dbCAN_4 | 0.8158 | 0.3093 | 0.6882 | 0.9435 | Eukaryote | CBM |
| dbCAN_4:HMMER | 0.5944 | 0.4421 | 0.4119 | 0.7769 | Eukaryote | CBM |
| dbCAN_4:DIAMOND | 0.9588 | 0.1566 | 0.8927 | 1.0250 | Eukaryote | CBM |
| dbCAN_4:dbCAN-sub | 0.7481 | 0.3526 | 0.6025 | 0.8936 | Eukaryote | CBM |
| CUPP | 0.0000 | 0.0000 | 0.0000 | 0.0000 | Eukaryote | CBM |
12.2.3 Precision
| Prediction_tool | Mean | Standard Deviation | LowerCI | UpperCI | Tax_group | CAZy_class |
|---|---|---|---|---|---|---|
| dbCAN_4 | 0.9123 | 0.2675 | 0.8646 | 0.9601 | All | GH |
| dbCAN_4:HMMER | 0.8993 | 0.2878 | 0.8484 | 0.9503 | All | GH |
| dbCAN_4:DIAMOND | 0.9395 | 0.2101 | 0.9017 | 0.9773 | All | GH |
| dbCAN_4:dbCAN-sub | 0.9058 | 0.2703 | 0.8576 | 0.9541 | All | GH |
| CUPP | 0.8186 | 0.3787 | 0.7504 | 0.8867 | All | GH |
| dbCAN_4 | 0.9582 | 0.1658 | 0.9230 | 0.9933 | Bacteria | GH |
| dbCAN_4:HMMER | 0.9311 | 0.2227 | 0.8839 | 0.9782 | Bacteria | GH |
| dbCAN_4:DIAMOND | 0.9767 | 0.0799 | 0.9598 | 0.9936 | Bacteria | GH |
| dbCAN_4:dbCAN-sub | 0.9474 | 0.1936 | 0.9066 | 0.9882 | Bacteria | GH |
| CUPP | 0.8541 | 0.3350 | 0.7831 | 0.9251 | Bacteria | GH |
| dbCAN_4 | 0.9245 | 0.2397 | 0.8840 | 0.9650 | Eukaryote | GH |
| dbCAN_4:HMMER | 0.9102 | 0.2626 | 0.8662 | 0.9543 | Eukaryote | GH |
| dbCAN_4:DIAMOND | 0.9509 | 0.1762 | 0.9209 | 0.9809 | Eukaryote | GH |
| dbCAN_4:dbCAN-sub | 0.9127 | 0.2535 | 0.8700 | 0.9553 | Eukaryote | GH |
| CUPP | 0.8331 | 0.3615 | 0.7715 | 0.8946 | Eukaryote | GH |
| dbCAN_4 | 0.9009 | 0.2717 | 0.8128 | 0.9889 | All | GT |
| dbCAN_4:HMMER | 0.8150 | 0.3713 | 0.7007 | 0.9292 | All | GT |
| dbCAN_4:DIAMOND | 0.9616 | 0.1679 | 0.9064 | 1.0168 | All | GT |
| dbCAN_4:dbCAN-sub | 0.8935 | 0.2719 | 0.8054 | 0.9817 | All | GT |
| CUPP | 0.8606 | 0.3419 | 0.7482 | 0.9729 | All | GT |
| dbCAN_4 | 0.8798 | 0.2651 | 0.8081 | 0.9514 | Bacteria | GT |
| dbCAN_4:HMMER | 0.8664 | 0.2635 | 0.7952 | 0.9377 | Bacteria | GT |
| dbCAN_4:DIAMOND | 0.9246 | 0.1979 | 0.8711 | 0.9781 | Bacteria | GT |
| dbCAN_4:dbCAN-sub | 0.8790 | 0.2648 | 0.8074 | 0.9506 | Bacteria | GT |
| CUPP | 0.8792 | 0.2704 | 0.8054 | 0.9531 | Bacteria | GT |
| dbCAN_4 | 0.8953 | 0.2508 | 0.8380 | 0.9526 | Eukaryote | GT |
| dbCAN_4:HMMER | 0.8646 | 0.2758 | 0.8020 | 0.9272 | Eukaryote | GT |
| dbCAN_4:DIAMOND | 0.9360 | 0.1985 | 0.8907 | 0.9814 | Eukaryote | GT |
| dbCAN_4:dbCAN-sub | 0.8940 | 0.2511 | 0.8366 | 0.9513 | Eukaryote | GT |
| CUPP | 0.8785 | 0.2933 | 0.8110 | 0.9460 | Eukaryote | GT |
| dbCAN_4 | 0.9091 | 0.2505 | 0.7980 | 1.0202 | All | PL |
| dbCAN_4:HMMER | 0.9091 | 0.2505 | 0.7980 | 1.0202 | All | PL |
| dbCAN_4:DIAMOND | 0.9318 | 0.1756 | 0.8540 | 1.0097 | All | PL |
| dbCAN_4:dbCAN-sub | 0.9091 | 0.2505 | 0.7980 | 1.0202 | All | PL |
| CUPP | 0.7727 | 0.4289 | 0.5825 | 0.9629 | All | PL |
| dbCAN_4 | 0.9514 | 0.1167 | 0.8538 | 1.0489 | Bacteria | PL |
| dbCAN_4:HMMER | 0.9514 | 0.1167 | 0.8538 | 1.0489 | Bacteria | PL |
| dbCAN_4:DIAMOND | 0.9014 | 0.1675 | 0.7614 | 1.0414 | Bacteria | PL |
| dbCAN_4:dbCAN-sub | 0.9514 | 0.1167 | 0.8538 | 1.0489 | Bacteria | PL |
| CUPP | 0.7326 | 0.4533 | 0.3537 | 1.1116 | Bacteria | PL |
| dbCAN_4 | 0.9210 | 0.2293 | 0.8219 | 1.0202 | Eukaryote | PL |
| dbCAN_4:HMMER | 0.9210 | 0.2293 | 0.8219 | 1.0202 | Eukaryote | PL |
| dbCAN_4:DIAMOND | 0.9329 | 0.1638 | 0.8620 | 1.0037 | Eukaryote | PL |
| dbCAN_4:dbCAN-sub | 0.9211 | 0.2293 | 0.8219 | 1.0202 | Eukaryote | PL |
| CUPP | 0.7796 | 0.4203 | 0.5979 | 0.9614 | Eukaryote | PL |
| dbCAN_4 | 0.8184 | 0.3054 | 0.6493 | 0.9875 | All | CE |
| dbCAN_4:HMMER | 0.8113 | 0.3024 | 0.6438 | 0.9787 | All | CE |
| dbCAN_4:DIAMOND | 0.8921 | 0.2058 | 0.7781 | 1.0061 | All | CE |
| dbCAN_4:dbCAN-sub | 0.8184 | 0.3054 | 0.6493 | 0.9875 | All | CE |
| CUPP | 0.7015 | 0.4142 | 0.4721 | 0.9309 | All | CE |
| dbCAN_4 | 0.7303 | 0.4233 | 0.4959 | 0.9647 | Bacteria | CE |
| dbCAN_4:HMMER | 0.7262 | 0.4214 | 0.4929 | 0.9596 | Bacteria | CE |
| dbCAN_4:DIAMOND | 0.8931 | 0.2307 | 0.7537 | 1.0325 | Bacteria | CE |
| dbCAN_4:dbCAN-sub | 0.7285 | 0.4223 | 0.4947 | 0.9624 | Bacteria | CE |
| CUPP | 0.6972 | 0.4468 | 0.4272 | 0.9672 | Bacteria | CE |
| dbCAN_4 | 0.7625 | 0.3416 | 0.5927 | 0.9324 | Eukaryote | CE |
| dbCAN_4:HMMER | 0.7511 | 0.3412 | 0.5814 | 0.9208 | Eukaryote | CE |
| dbCAN_4:DIAMOND | 0.8751 | 0.2163 | 0.7639 | 0.9863 | Eukaryote | CE |
| dbCAN_4:dbCAN-sub | 0.7613 | 0.3408 | 0.5918 | 0.9307 | Eukaryote | CE |
| CUPP | 0.6687 | 0.4313 | 0.4470 | 0.8905 | Eukaryote | CE |
| dbCAN_4 | 1.0000 | NA | NaN | NaN | All | AA |
| dbCAN_4:HMMER | 1.0000 | NA | NaN | NaN | All | AA |
| dbCAN_4:DIAMOND | 1.0000 | NA | NaN | NaN | All | AA |
| dbCAN_4:dbCAN-sub | 1.0000 | NA | NaN | NaN | All | AA |
| CUPP | 1.0000 | NA | NaN | NaN | All | AA |
| dbCAN_4 | 0.8273 | 0.2732 | 0.6760 | 0.9786 | Bacteria | AA |
| dbCAN_4:HMMER | 0.8210 | 0.2769 | 0.6677 | 0.9744 | Bacteria | AA |
| dbCAN_4:DIAMOND | 0.8457 | 0.1809 | 0.7455 | 0.9459 | Bacteria | AA |
| dbCAN_4:dbCAN-sub | 0.8238 | 0.2747 | 0.6717 | 0.9759 | Bacteria | AA |
| CUPP | 0.6278 | 0.4369 | 0.3858 | 0.8698 | Bacteria | AA |
| dbCAN_4 | 0.8381 | 0.2675 | 0.6956 | 0.9806 | Eukaryote | AA |
| dbCAN_4:HMMER | 0.8322 | 0.2712 | 0.6877 | 0.9767 | Eukaryote | AA |
| dbCAN_4:DIAMOND | 0.8553 | 0.1790 | 0.7600 | 0.9507 | Eukaryote | AA |
| dbCAN_4:dbCAN-sub | 0.8348 | 0.2690 | 0.6915 | 0.9781 | Eukaryote | AA |
| CUPP | 0.6511 | 0.4322 | 0.4207 | 0.8814 | Eukaryote | AA |
| dbCAN_4 | 0.8194 | 0.3638 | 0.7125 | 0.9262 | All | CBM |
| dbCAN_4:HMMER | 0.7895 | 0.3856 | 0.6763 | 0.9028 | All | CBM |
| dbCAN_4:DIAMOND | 0.8369 | 0.3245 | 0.7405 | 0.9332 | All | CBM |
| dbCAN_4:dbCAN-sub | 0.8138 | 0.3652 | 0.7065 | 0.9210 | All | CBM |
| CUPP | 0.0000 | 0.0000 | 0.0000 | 0.0000 | All | CBM |
| dbCAN_4 | 0.9374 | 0.2020 | 0.8540 | 1.0208 | Bacteria | CBM |
| dbCAN_4:HMMER | 0.7908 | 0.4051 | 0.6236 | 0.9580 | Bacteria | CBM |
| dbCAN_4:DIAMOND | 0.9409 | 0.1372 | 0.8830 | 0.9988 | Bacteria | CBM |
| dbCAN_4:dbCAN-sub | 0.8766 | 0.2852 | 0.7589 | 0.9943 | Bacteria | CBM |
| CUPP | 0.0000 | 0.0000 | 0.0000 | 0.0000 | Bacteria | CBM |
| dbCAN_4 | 0.8451 | 0.3412 | 0.7537 | 0.9364 | Eukaryote | CBM |
| dbCAN_4:HMMER | 0.8028 | 0.3786 | 0.7014 | 0.9042 | Eukaryote | CBM |
| dbCAN_4:DIAMOND | 0.8676 | 0.2812 | 0.7916 | 0.9436 | Eukaryote | CBM |
| dbCAN_4:dbCAN-sub | 0.8212 | 0.3608 | 0.7246 | 0.9179 | Eukaryote | CBM |
| CUPP | 0.0000 | 0.0000 | 0.0000 | 0.0000 | Eukaryote | CBM |
12.2.4 F1-score
## X CAZy_family Prediction_tool Statistic_parameter Statistic_value
## 401182 40117 AA10 dbCAN_4 F1-score 1.0000000
## 446852 44684 AA10 dbCAN_4:HMMER F1-score 1.0000000
## 492612 49260 AA10 dbCAN_4:DIAMOND F1-score 0.9677419
## 538352 53834 AA10 dbCAN_4:dbCAN-sub F1-score 1.0000000
## 584112 58410 AA10 CUPP F1-score 1.0000000
## CAZy_class Tax_group
## 401182 AA Bacteria
## 446852 AA Bacteria
## 492612 AA Bacteria
## 538352 AA Bacteria
## 584112 AA Bacteria| Prediction_tool | Mean | Standard Deviation | LowerCI | UpperCI | Tax_group | CAZy_class |
|---|---|---|---|---|---|---|
| dbCAN_4 | 0.9200 | 0.2349 | 0.8804 | 0.9597 | All | GH |
| dbCAN_4:HMMER | 0.8927 | 0.2643 | 0.8483 | 0.9370 | All | GH |
| dbCAN_4:DIAMOND | 0.9485 | 0.1730 | 0.9190 | 0.9779 | All | GH |
| dbCAN_4:dbCAN-sub | 0.9079 | 0.2481 | 0.8661 | 0.9496 | All | GH |
| CUPP | 0.8005 | 0.3601 | 0.7392 | 0.8618 | All | GH |
| dbCAN_4 | 0.9047 | 0.2624 | 0.8579 | 0.9515 | Bacteria | GH |
| dbCAN_4:HMMER | 0.8834 | 0.2834 | 0.8333 | 0.9336 | Bacteria | GH |
| dbCAN_4:DIAMOND | 0.9340 | 0.2070 | 0.8968 | 0.9713 | Bacteria | GH |
| dbCAN_4:dbCAN-sub | 0.8981 | 0.2645 | 0.8509 | 0.9453 | Bacteria | GH |
| CUPP | 0.7968 | 0.3740 | 0.7295 | 0.8641 | Bacteria | GH |
| dbCAN_4 | 0.9589 | 0.1615 | 0.9247 | 0.9931 | Eukaryote | GH |
| dbCAN_4:HMMER | 0.9179 | 0.2212 | 0.8710 | 0.9648 | Eukaryote | GH |
| dbCAN_4:DIAMOND | 0.9774 | 0.0711 | 0.9623 | 0.9925 | Eukaryote | GH |
| dbCAN_4:dbCAN-sub | 0.9478 | 0.1900 | 0.9078 | 0.9878 | Eukaryote | GH |
| CUPP | 0.8374 | 0.3315 | 0.7672 | 0.9077 | Eukaryote | GH |
| dbCAN_4 | 0.8923 | 0.2395 | 0.8376 | 0.9471 | All | GT |
| dbCAN_4:HMMER | 0.8503 | 0.2674 | 0.7897 | 0.9110 | All | GT |
| dbCAN_4:DIAMOND | 0.9263 | 0.1884 | 0.8832 | 0.9693 | All | GT |
| dbCAN_4:dbCAN-sub | 0.8915 | 0.2396 | 0.8368 | 0.9463 | All | GT |
| CUPP | 0.8230 | 0.2883 | 0.7567 | 0.8893 | All | GT |
| dbCAN_4 | 0.8655 | 0.2772 | 0.7757 | 0.9554 | Bacteria | GT |
| dbCAN_4:HMMER | 0.7651 | 0.3603 | 0.6543 | 0.8760 | Bacteria | GT |
| dbCAN_4:DIAMOND | 0.9146 | 0.1907 | 0.8519 | 0.9773 | Bacteria | GT |
| dbCAN_4:dbCAN-sub | 0.8610 | 0.2760 | 0.7715 | 0.9505 | Bacteria | GT |
| CUPP | 0.8216 | 0.3331 | 0.7121 | 0.9311 | Bacteria | GT |
| dbCAN_4 | 0.8900 | 0.2459 | 0.8235 | 0.9565 | Eukaryote | GT |
| dbCAN_4:HMMER | 0.8545 | 0.2544 | 0.7858 | 0.9233 | Eukaryote | GT |
| dbCAN_4:DIAMOND | 0.9344 | 0.1731 | 0.8876 | 0.9812 | Eukaryote | GT |
| dbCAN_4:dbCAN-sub | 0.8900 | 0.2459 | 0.8236 | 0.9565 | Eukaryote | GT |
| CUPP | 0.8192 | 0.2627 | 0.7475 | 0.8910 | Eukaryote | GT |
| dbCAN_4 | 0.9135 | 0.2222 | 0.8174 | 1.0096 | All | PL |
| dbCAN_4:HMMER | 0.9135 | 0.2222 | 0.8174 | 1.0096 | All | PL |
| dbCAN_4:DIAMOND | 0.9489 | 0.1312 | 0.8922 | 1.0057 | All | PL |
| dbCAN_4:dbCAN-sub | 0.9139 | 0.2223 | 0.8177 | 1.0100 | All | PL |
| CUPP | 0.7307 | 0.4094 | 0.5537 | 0.9077 | All | PL |
| dbCAN_4 | 0.9021 | 0.2333 | 0.7987 | 1.0055 | Bacteria | PL |
| dbCAN_4:HMMER | 0.9021 | 0.2333 | 0.7987 | 1.0055 | Bacteria | PL |
| dbCAN_4:DIAMOND | 0.9465 | 0.1396 | 0.8846 | 1.0084 | Bacteria | PL |
| dbCAN_4:dbCAN-sub | 0.9026 | 0.2335 | 0.7991 | 1.0061 | Bacteria | PL |
| CUPP | 0.7198 | 0.4156 | 0.5355 | 0.9040 | Bacteria | PL |
| dbCAN_4 | 0.9714 | 0.0700 | 0.9129 | 1.0299 | Eukaryote | PL |
| dbCAN_4:HMMER | 0.9714 | 0.0700 | 0.9129 | 1.0299 | Eukaryote | PL |
| dbCAN_4:DIAMOND | 0.9402 | 0.1033 | 0.8538 | 1.0265 | Eukaryote | PL |
| dbCAN_4:dbCAN-sub | 0.9714 | 0.0700 | 0.9129 | 1.0299 | Eukaryote | PL |
| CUPP | 0.7410 | 0.4576 | 0.3584 | 1.1236 | Eukaryote | PL |
| dbCAN_4 | 0.8015 | 0.3232 | 0.6408 | 0.9622 | All | CE |
| dbCAN_4:HMMER | 0.7905 | 0.3222 | 0.6303 | 0.9508 | All | CE |
| dbCAN_4:DIAMOND | 0.9041 | 0.1502 | 0.8269 | 0.9814 | All | CE |
| dbCAN_4:dbCAN-sub | 0.8015 | 0.3232 | 0.6408 | 0.9622 | All | CE |
| CUPP | 0.6880 | 0.4173 | 0.4734 | 0.9025 | All | CE |
| dbCAN_4 | 0.8515 | 0.2802 | 0.6963 | 1.0066 | Bacteria | CE |
| dbCAN_4:HMMER | 0.8435 | 0.2780 | 0.6895 | 0.9974 | Bacteria | CE |
| dbCAN_4:DIAMOND | 0.9062 | 0.1399 | 0.8287 | 0.9837 | Bacteria | CE |
| dbCAN_4:dbCAN-sub | 0.8515 | 0.2802 | 0.6963 | 1.0066 | Bacteria | CE |
| CUPP | 0.7259 | 0.4042 | 0.5020 | 0.9497 | Bacteria | CE |
| dbCAN_4 | 0.7453 | 0.4141 | 0.5160 | 0.9746 | Eukaryote | CE |
| dbCAN_4:HMMER | 0.7376 | 0.4112 | 0.5099 | 0.9654 | Eukaryote | CE |
| dbCAN_4:DIAMOND | 0.9092 | 0.1817 | 0.7994 | 1.0190 | Eukaryote | CE |
| dbCAN_4:dbCAN-sub | 0.7454 | 0.4141 | 0.5160 | 0.9747 | Eukaryote | CE |
| CUPP | 0.7054 | 0.4327 | 0.4439 | 0.9669 | Eukaryote | CE |
| dbCAN_4 | 0.8626 | 0.2485 | 0.7302 | 0.9950 | All | AA |
| dbCAN_4:HMMER | 0.8577 | 0.2494 | 0.7248 | 0.9906 | All | AA |
| dbCAN_4:DIAMOND | 0.8972 | 0.1371 | 0.8242 | 0.9703 | All | AA |
| dbCAN_4:dbCAN-sub | 0.8600 | 0.2489 | 0.7273 | 0.9926 | All | AA |
| CUPP | 0.6685 | 0.4320 | 0.4383 | 0.8987 | All | AA |
| dbCAN_4 | 1.0000 | NA | NaN | NaN | Bacteria | AA |
| dbCAN_4:HMMER | 1.0000 | NA | NaN | NaN | Bacteria | AA |
| dbCAN_4:DIAMOND | 0.9677 | NA | NaN | NaN | Bacteria | AA |
| dbCAN_4:dbCAN-sub | 1.0000 | NA | NaN | NaN | Bacteria | AA |
| CUPP | 1.0000 | NA | NaN | NaN | Bacteria | AA |
| dbCAN_4 | 0.8534 | 0.2544 | 0.7126 | 0.9943 | Eukaryote | AA |
| dbCAN_4:HMMER | 0.8482 | 0.2552 | 0.7069 | 0.9896 | Eukaryote | AA |
| dbCAN_4:DIAMOND | 0.8925 | 0.1406 | 0.8147 | 0.9704 | Eukaryote | AA |
| dbCAN_4:dbCAN-sub | 0.8506 | 0.2547 | 0.7096 | 0.9917 | Eukaryote | AA |
| CUPP | 0.6464 | 0.4377 | 0.4040 | 0.8887 | Eukaryote | AA |
| dbCAN_4 | 0.8144 | 0.3410 | 0.7231 | 0.9057 | All | CBM |
| dbCAN_4:HMMER | 0.7349 | 0.3862 | 0.6314 | 0.8383 | All | CBM |
| dbCAN_4:DIAMOND | 0.8581 | 0.2917 | 0.7793 | 0.9370 | All | CBM |
| dbCAN_4:dbCAN-sub | 0.7832 | 0.3592 | 0.6870 | 0.8794 | All | CBM |
| CUPP | 0.0000 | 0.0000 | 0.0000 | 0.0000 | All | CBM |
| dbCAN_4 | 0.8130 | 0.3508 | 0.7101 | 0.9160 | Bacteria | CBM |
| dbCAN_4:HMMER | 0.7499 | 0.3832 | 0.6373 | 0.8624 | Bacteria | CBM |
| dbCAN_4:DIAMOND | 0.8356 | 0.3190 | 0.7409 | 0.9304 | Bacteria | CBM |
| dbCAN_4:dbCAN-sub | 0.8128 | 0.3510 | 0.7098 | 0.9159 | Bacteria | CBM |
| CUPP | 0.0000 | 0.0000 | 0.0000 | 0.0000 | Bacteria | CBM |
| dbCAN_4 | 0.8457 | 0.2728 | 0.7331 | 0.9583 | Eukaryote | CBM |
| dbCAN_4:HMMER | 0.6262 | 0.4342 | 0.4470 | 0.8054 | Eukaryote | CBM |
| dbCAN_4:DIAMOND | 0.9323 | 0.1562 | 0.8663 | 0.9983 | Eukaryote | CBM |
| dbCAN_4:dbCAN-sub | 0.7803 | 0.3240 | 0.6465 | 0.9140 | Eukaryote | CBM |
| CUPP | 0.0000 | 0.0000 | 0.0000 | 0.0000 | Eukaryote | CBM |
12.2.4.1 Test for statistically significant differences in the means
## Df Sum Sq Mean Sq F value Pr(>F)
## Tax_group 2 0.6 0.295 3.210 0.0405 *
## Prediction_tool 4 33.0 8.247 89.586 <2e-16 ***
## Tax_group:Prediction_tool 8 0.3 0.035 0.377 0.9332
## Residuals 3867 356.0 0.092
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1## Df Sum Sq Mean Sq F value Pr(>F)
## Tax_group 2 0.53 0.2664 3.974 0.019 *
## Prediction_tool 4 4.05 1.0119 15.098 3.9e-12 ***
## Tax_group:Prediction_tool 8 0.02 0.0022 0.033 1.000
## Residuals 1723 115.48 0.0670
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistic_value ~ Tax_group * Prediction_tool, data = all.df.stat.gh)
##
## $`Tax_group:Prediction_tool`
## diff lwr
## Bacteria:dbCAN_4-All:dbCAN_4 -0.015346012 -0.12456122
## Eukaryote:dbCAN_4-All:dbCAN_4 0.038835514 -0.08127995
## All:dbCAN_4:HMMER-All:dbCAN_4 -0.027379274 -0.13323056
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4 -0.036615315 -0.14536917
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4 -0.002133407 -0.12224888
## All:dbCAN_4:DIAMOND-All:dbCAN_4 0.028416222 -0.07821063
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4 0.013962618 -0.09572717
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4 0.057353293 -0.06276218
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4 -0.012163968 -0.11820546
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4 -0.021958848 -0.13117406
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4 0.027744987 -0.09195889
## All:CUPP-All:dbCAN_4 -0.119549664 -0.22617652
## Bacteria:CUPP-All:dbCAN_4 -0.123267269 -0.23295705
## Eukaryote:CUPP-All:dbCAN_4 -0.082619465 -0.20273493
## Eukaryote:dbCAN_4-Bacteria:dbCAN_4 0.054181526 -0.06857840
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4 -0.012033262 -0.12087613
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4 -0.021269303 -0.13293700
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4 0.013212606 -0.10954733
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 0.043762234 -0.06583503
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 0.029308630 -0.08327078
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 0.072699305 -0.05006063
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 0.003182044 -0.10584581
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 -0.006612835 -0.11872991
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 0.043090999 -0.07926624
## All:CUPP-Bacteria:dbCAN_4 -0.104203652 -0.21380092
## Bacteria:CUPP-Bacteria:dbCAN_4 -0.107921257 -0.22050067
## Eukaryote:CUPP-Bacteria:dbCAN_4 -0.067273453 -0.19003338
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -0.066214788 -0.18599180
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -0.075450829 -0.19780049
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -0.040968921 -0.17351991
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 -0.010419292 -0.13088225
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 -0.024872896 -0.14805523
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 0.018517779 -0.11403321
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 -0.050999482 -0.17094462
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 -0.060794361 -0.18355429
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 -0.011090527 -0.14326865
## All:CUPP-Eukaryote:dbCAN_4 -0.158385178 -0.27884813
## Bacteria:CUPP-Eukaryote:dbCAN_4 -0.162102783 -0.28528511
## Eukaryote:CUPP-Eukaryote:dbCAN_4 -0.121454979 -0.25400596
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:HMMER -0.009236041 -0.11761597
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:HMMER 0.025245867 -0.09453115
## All:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER 0.055795496 -0.05044994
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER 0.041341892 -0.06797717
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER 0.084732567 -0.03504445
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER 0.015215306 -0.09044266
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER 0.005420427 -0.10342244
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER 0.055124261 -0.06424000
## All:CUPP-All:dbCAN_4:HMMER -0.092170390 -0.19841583
## Bacteria:CUPP-All:dbCAN_4:HMMER -0.095887995 -0.20520705
## Eukaryote:CUPP-All:dbCAN_4:HMMER -0.055240191 -0.17501721
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:HMMER 0.034481909 -0.08786775
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER 0.065031537 -0.04410598
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER 0.050577933 -0.06155396
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER 0.093968608 -0.02838105
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER 0.024451347 -0.08411435
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER 0.014656468 -0.09701123
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER 0.064360302 -0.05758531
## All:CUPP-Bacteria:dbCAN_4:HMMER -0.082934349 -0.19207187
## Bacteria:CUPP-Bacteria:dbCAN_4:HMMER -0.086651954 -0.19878385
## Eukaryote:CUPP-Bacteria:dbCAN_4:HMMER -0.046004150 -0.16835381
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER 0.030549629 -0.08991333
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER 0.016096025 -0.10708631
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER 0.059486699 -0.07306429
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER -0.010030561 -0.12997570
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER -0.019825441 -0.14258537
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER 0.029878394 -0.10229973
## All:CUPP-Eukaryote:dbCAN_4:HMMER -0.117416257 -0.23787921
## Bacteria:CUPP-Eukaryote:dbCAN_4:HMMER -0.121133862 -0.24431619
## Eukaryote:CUPP-Eukaryote:dbCAN_4:HMMER -0.080486059 -0.21303704
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND -0.014453604 -0.12452379
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND 0.028937071 -0.09152588
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND -0.040580190 -0.14701512
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND -0.050375070 -0.15997233
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND -0.000671235 -0.12072379
## All:CUPP-All:dbCAN_4:DIAMOND -0.147965886 -0.25498403
## Bacteria:CUPP-All:dbCAN_4:DIAMOND -0.151683491 -0.26175368
## Eukaryote:CUPP-All:dbCAN_4:DIAMOND -0.111035688 -0.23149864
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:DIAMOND 0.043390674 -0.07979166
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND -0.026126586 -0.13562982
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND -0.035921466 -0.14850088
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND 0.013782369 -0.10899866
## All:CUPP-Bacteria:dbCAN_4:DIAMOND -0.133512282 -0.24358247
## Bacteria:CUPP-Bacteria:dbCAN_4:DIAMOND -0.137229887 -0.25026975
## Eukaryote:CUPP-Bacteria:dbCAN_4:DIAMOND -0.096582084 -0.21976442
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND -0.069517261 -0.18946240
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND -0.079312140 -0.20207207
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND -0.029608306 -0.16178643
## All:CUPP-Eukaryote:dbCAN_4:DIAMOND -0.176902957 -0.29736591
## Bacteria:CUPP-Eukaryote:dbCAN_4:DIAMOND -0.180620562 -0.30380289
## Eukaryote:CUPP-Eukaryote:dbCAN_4:DIAMOND -0.139972758 -0.27252374
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub -0.009794879 -0.11882273
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub 0.039908955 -0.07962401
## All:CUPP-All:dbCAN_4:dbCAN-sub -0.107385696 -0.21382063
## Bacteria:CUPP-All:dbCAN_4:dbCAN-sub -0.111103301 -0.22060654
## Eukaryote:CUPP-All:dbCAN_4:dbCAN-sub -0.070455497 -0.19040063
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:dbCAN-sub 0.049703835 -0.07265341
## All:CUPP-Bacteria:dbCAN_4:dbCAN-sub -0.097590817 -0.20718808
## Bacteria:CUPP-Bacteria:dbCAN_4:dbCAN-sub -0.101308422 -0.21388783
## Eukaryote:CUPP-Bacteria:dbCAN_4:dbCAN-sub -0.060660618 -0.18342055
## All:CUPP-Eukaryote:dbCAN_4:dbCAN-sub -0.147294651 -0.26734721
## Bacteria:CUPP-Eukaryote:dbCAN_4:dbCAN-sub -0.151012256 -0.27379328
## Eukaryote:CUPP-Eukaryote:dbCAN_4:dbCAN-sub -0.110364453 -0.24254258
## Bacteria:CUPP-All:CUPP -0.003717605 -0.11378779
## Eukaryote:CUPP-All:CUPP 0.036930199 -0.08353276
## Eukaryote:CUPP-Bacteria:CUPP 0.040647804 -0.08253453
## upr p adj
## Bacteria:dbCAN_4-All:dbCAN_4 0.0938692000 1.0000000
## Eukaryote:dbCAN_4-All:dbCAN_4 0.1589509823 0.9989612
## All:dbCAN_4:HMMER-All:dbCAN_4 0.0784720164 0.9999215
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4 0.0721385385 0.9983834
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4 0.1179820617 1.0000000
## All:dbCAN_4:DIAMOND-All:dbCAN_4 0.1350430733 0.9998876
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4 0.1236524029 1.0000000
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4 0.1774687611 0.9540574
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4 0.0938775215 1.0000000
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4 0.0872563648 0.9999966
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4 0.1474488685 0.9999795
## All:CUPP-All:dbCAN_4 -0.0129228130 0.0121839
## Bacteria:CUPP-All:dbCAN_4 -0.0135774843 0.0117936
## Eukaryote:CUPP-All:dbCAN_4 0.0374960030 0.5634300
## Eukaryote:dbCAN_4-Bacteria:dbCAN_4 0.1769414572 0.9764556
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4 0.0968096094 1.0000000
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4 0.0903983989 0.9999983
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4 0.1359725366 1.0000000
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 0.1533594985 0.9906942
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 0.1418880415 0.9999151
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 0.1954592360 0.7917623
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 0.1122098958 1.0000000
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 0.1055042354 1.0000000
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 0.1654482392 0.9973872
## All:CUPP-Bacteria:dbCAN_4 0.0053936122 0.0828414
## Bacteria:CUPP-Bacteria:dbCAN_4 0.0046581543 0.0766562
## Eukaryote:CUPP-Bacteria:dbCAN_4 0.0554864779 0.8720065
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4 0.0535622289 0.8643356
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4 0.0468988287 0.7388109
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4 0.0915820651 0.9993714
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 0.1100436629 1.0000000
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 0.0983094363 0.9999964
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 0.1510687645 1.0000000
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 0.0689456537 0.9831811
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 0.0619655696 0.9385845
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 0.1210876003 1.0000000
## All:CUPP-Eukaryote:dbCAN_4 -0.0379222234 0.0008198
## Bacteria:CUPP-Eukaryote:dbCAN_4 -0.0389204509 0.0008055
## Eukaryote:CUPP-Eukaryote:dbCAN_4 0.0110960064 0.1150682
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:HMMER 0.0991438865 1.0000000
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:HMMER 0.1450228841 0.9999938
## All:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER 0.1620409356 0.9047692
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER 0.1506609522 0.9945570
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER 0.2045095835 0.5131426
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER 0.1208732707 1.0000000
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER 0.1142632977 1.0000000
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER 0.1744885239 0.9651596
## All:CUPP-All:dbCAN_4:HMMER 0.0140750493 0.1763739
## Bacteria:CUPP-All:dbCAN_4:HMMER 0.0134310650 0.1627079
## Eukaryote:CUPP-All:dbCAN_4:HMMER 0.0645368255 0.9655553
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:HMMER 0.1568315663 0.9997824
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER 0.1741690579 0.7841907
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER 0.1627098284 0.9715211
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER 0.2163182656 0.3646932
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER 0.1330170439 0.9999857
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER 0.1263241694 1.0000000
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER 0.1863059141 0.9013197
## All:CUPP-Bacteria:dbCAN_4:HMMER 0.0262031716 0.3835181
## Bacteria:CUPP-Bacteria:dbCAN_4:HMMER 0.0254799412 0.3539265
## Eukaryote:CUPP-Bacteria:dbCAN_4:HMMER 0.0763455076 0.9948639
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER 0.1510125835 0.9999381
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER 0.1392783569 1.0000000
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER 0.1920376850 0.9727438
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER 0.1099145742 1.0000000
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER 0.1029344902 0.9999998
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER 0.1620565209 0.9999850
## All:CUPP-Eukaryote:dbCAN_4:HMMER 0.0030466971 0.0651505
## Bacteria:CUPP-Eukaryote:dbCAN_4:HMMER 0.0020484697 0.0595773
## Eukaryote:CUPP-Eukaryote:dbCAN_4:HMMER 0.0520649270 0.7599361
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND 0.0956165852 1.0000000
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND 0.1494000251 0.9999681
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND 0.0658547438 0.9940937
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND 0.0592221944 0.9665264
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND 0.1193813239 1.0000000
## All:CUPP-All:dbCAN_4:DIAMOND -0.0409477427 0.0002835
## Bacteria:CUPP-All:dbCAN_4:DIAMOND -0.0416133020 0.0003050
## Eukaryote:CUPP-All:dbCAN_4:DIAMOND 0.0094272671 0.1094009
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:DIAMOND 0.1665730065 0.9973814
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND 0.0833766497 0.9999706
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND 0.0766579453 0.9991025
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND 0.1365633951 1.0000000
## All:CUPP-Bacteria:dbCAN_4:DIAMOND -0.0234420931 0.0036135
## Bacteria:CUPP-Bacteria:dbCAN_4:DIAMOND -0.0241900268 0.0035626
## Eukaryote:CUPP-Bacteria:dbCAN_4:DIAMOND 0.0266002485 0.3288945
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND 0.0504278749 0.8168575
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND 0.0434477908 0.6691200
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND 0.1025698215 0.9999866
## All:CUPP-Eukaryote:dbCAN_4:DIAMOND -0.0564400022 0.0000681
## Bacteria:CUPP-Eukaryote:dbCAN_4:DIAMOND -0.0574382297 0.0000708
## Eukaryote:CUPP-Eukaryote:dbCAN_4:DIAMOND -0.0074217724 0.0268009
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub 0.0992329723 1.0000000
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub 0.1594419175 0.9985235
## All:CUPP-All:dbCAN_4:dbCAN-sub -0.0009507618 0.0454208
## Bacteria:CUPP-All:dbCAN_4:dbCAN-sub -0.0016000649 0.0427007
## Eukaryote:CUPP-All:dbCAN_4:dbCAN-sub 0.0494896385 0.8015090
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:dbCAN-sub 0.1720610744 0.9890256
## All:CUPP-Bacteria:dbCAN_4:dbCAN-sub 0.0120064474 0.1450969
## Bacteria:CUPP-Bacteria:dbCAN_4:dbCAN-sub 0.0112709895 0.1335101
## Eukaryote:CUPP-Bacteria:dbCAN_4:dbCAN-sub 0.0620993131 0.9396286
## All:CUPP-Eukaryote:dbCAN_4:dbCAN-sub -0.0272420924 0.0029734
## Bacteria:CUPP-Eukaryote:dbCAN_4:dbCAN-sub -0.0282312301 0.0028497
## Eukaryote:CUPP-Eukaryote:dbCAN_4:dbCAN-sub 0.0218136745 0.2286732
## Bacteria:CUPP-All:CUPP 0.1063525844 1.0000000
## Eukaryote:CUPP-All:CUPP 0.1573931534 0.9994267
## Eukaryote:CUPP-Bacteria:CUPP 0.1638301357 0.9987005## Df Sum Sq Mean Sq F value Pr(>F)
## Tax_group 2 0.17 0.08504 1.296 0.27428
## Prediction_tool 4 1.26 0.31574 4.810 0.00077 ***
## Tax_group:Prediction_tool 8 0.14 0.01766 0.269 0.97580
## Residuals 836 54.87 0.06564
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistic_value ~ Tax_group * Prediction_tool, data = all.df.stat.gt)
##
## $`Tax_group:Prediction_tool`
## diff
## Bacteria:dbCAN_4-All:dbCAN_4 -2.679218e-02
## Eukaryote:dbCAN_4-All:dbCAN_4 -2.345440e-03
## All:dbCAN_4:HMMER-All:dbCAN_4 -4.197588e-02
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4 -1.271907e-01
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4 -3.779756e-02
## All:dbCAN_4:DIAMOND-All:dbCAN_4 3.392678e-02
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4 2.229773e-02
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4 4.205081e-02
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4 -7.795292e-04
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4 -3.132937e-02
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4 -2.291219e-03
## All:CUPP-All:dbCAN_4 -6.931319e-02
## Bacteria:CUPP-All:dbCAN_4 -7.069749e-02
## Eukaryote:CUPP-All:dbCAN_4 -7.307656e-02
## Eukaryote:dbCAN_4-Bacteria:dbCAN_4 2.444674e-02
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4 -1.518370e-02
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4 -1.003985e-01
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4 -1.100538e-02
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 6.071896e-02
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 4.908991e-02
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 6.884299e-02
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 2.601265e-02
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 -4.537192e-03
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 2.450096e-02
## All:CUPP-Bacteria:dbCAN_4 -4.252101e-02
## Bacteria:CUPP-Bacteria:dbCAN_4 -4.390530e-02
## Eukaryote:CUPP-Bacteria:dbCAN_4 -4.628438e-02
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -3.963044e-02
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -1.248453e-01
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -3.545212e-02
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 3.627222e-02
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 2.464317e-02
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 4.439625e-02
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 1.565911e-03
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 -2.898393e-02
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 5.422092e-05
## All:CUPP-Eukaryote:dbCAN_4 -6.696775e-02
## Bacteria:CUPP-Eukaryote:dbCAN_4 -6.835205e-02
## Eukaryote:CUPP-Eukaryote:dbCAN_4 -7.073112e-02
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:HMMER -8.521485e-02
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:HMMER 4.178317e-03
## All:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER 7.590265e-02
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER 6.427360e-02
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER 8.402669e-02
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER 4.119635e-02
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER 1.064650e-02
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER 3.968466e-02
## All:CUPP-All:dbCAN_4:HMMER -2.733731e-02
## Bacteria:CUPP-All:dbCAN_4:HMMER -2.872161e-02
## Eukaryote:CUPP-All:dbCAN_4:HMMER -3.110069e-02
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:HMMER 8.939317e-02
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER 1.611175e-01
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER 1.494885e-01
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER 1.692415e-01
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER 1.264112e-01
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER 9.586136e-02
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER 1.248995e-01
## All:CUPP-Bacteria:dbCAN_4:HMMER 5.787754e-02
## Bacteria:CUPP-Bacteria:dbCAN_4:HMMER 5.649324e-02
## Eukaryote:CUPP-Bacteria:dbCAN_4:HMMER 5.411416e-02
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER 7.172434e-02
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER 6.009529e-02
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER 7.984837e-02
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER 3.701803e-02
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER 6.468186e-03
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER 3.550634e-02
## All:CUPP-Eukaryote:dbCAN_4:HMMER -3.151563e-02
## Bacteria:CUPP-Eukaryote:dbCAN_4:HMMER -3.289993e-02
## Eukaryote:CUPP-Eukaryote:dbCAN_4:HMMER -3.527901e-02
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND -1.162905e-02
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND 8.124036e-03
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND -3.470630e-02
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND -6.525615e-02
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND -3.621799e-02
## All:CUPP-All:dbCAN_4:DIAMOND -1.032400e-01
## Bacteria:CUPP-All:dbCAN_4:DIAMOND -1.046243e-01
## Eukaryote:CUPP-All:dbCAN_4:DIAMOND -1.070033e-01
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:DIAMOND 1.975308e-02
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND -2.307726e-02
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND -5.362710e-02
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND -2.458895e-02
## All:CUPP-Bacteria:dbCAN_4:DIAMOND -9.161092e-02
## Bacteria:CUPP-Bacteria:dbCAN_4:DIAMOND -9.299521e-02
## Eukaryote:CUPP-Bacteria:dbCAN_4:DIAMOND -9.537429e-02
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND -4.283034e-02
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND -7.338019e-02
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND -4.434203e-02
## All:CUPP-Eukaryote:dbCAN_4:DIAMOND -1.113640e-01
## Bacteria:CUPP-Eukaryote:dbCAN_4:DIAMOND -1.127483e-01
## Eukaryote:CUPP-Eukaryote:dbCAN_4:DIAMOND -1.151274e-01
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub -3.054984e-02
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub -1.511690e-03
## All:CUPP-All:dbCAN_4:dbCAN-sub -6.853366e-02
## Bacteria:CUPP-All:dbCAN_4:dbCAN-sub -6.991796e-02
## Eukaryote:CUPP-All:dbCAN_4:dbCAN-sub -7.229704e-02
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:dbCAN-sub 2.903815e-02
## All:CUPP-Bacteria:dbCAN_4:dbCAN-sub -3.798382e-02
## Bacteria:CUPP-Bacteria:dbCAN_4:dbCAN-sub -3.936811e-02
## Eukaryote:CUPP-Bacteria:dbCAN_4:dbCAN-sub -4.174719e-02
## All:CUPP-Eukaryote:dbCAN_4:dbCAN-sub -6.702197e-02
## Bacteria:CUPP-Eukaryote:dbCAN_4:dbCAN-sub -6.840627e-02
## Eukaryote:CUPP-Eukaryote:dbCAN_4:dbCAN-sub -7.078535e-02
## Bacteria:CUPP-All:CUPP -1.384295e-03
## Eukaryote:CUPP-All:CUPP -3.763374e-03
## Eukaryote:CUPP-Bacteria:CUPP -2.379079e-03
## lwr upr
## Bacteria:dbCAN_4-All:dbCAN_4 -0.198450956 0.14486659
## Eukaryote:dbCAN_4-All:dbCAN_4 -0.156623331 0.15193245
## All:dbCAN_4:HMMER-All:dbCAN_4 -0.182888449 0.09893670
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4 -0.293489349 0.03910789
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4 -0.192075451 0.11648033
## All:dbCAN_4:DIAMOND-All:dbCAN_4 -0.107445546 0.17529910
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4 -0.150847298 0.19544275
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4 -0.112227080 0.19632870
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4 -0.142151851 0.14059279
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4 -0.202988148 0.14032940
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4 -0.156569110 0.15198667
## All:CUPP-All:dbCAN_4 -0.211155971 0.07252959
## Bacteria:CUPP-All:dbCAN_4 -0.243842512 0.10244754
## Eukaryote:CUPP-All:dbCAN_4 -0.228180990 0.08202786
## Eukaryote:dbCAN_4-Bacteria:dbCAN_4 -0.157987547 0.20688103
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4 -0.186464035 0.15609665
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4 -0.293105146 0.09230805
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4 -0.193439667 0.17142891
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 -0.110939818 0.23237773
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 -0.149555004 0.24773482
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 -0.113591295 0.25127728
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 -0.145646123 0.19767143
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 -0.201887988 0.19281360
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 -0.157933326 0.20693525
## All:CUPP-Bacteria:dbCAN_4 -0.214567445 0.12952543
## Bacteria:CUPP-Bacteria:dbCAN_4 -0.242550218 0.15473961
## Eukaryote:CUPP-Bacteria:dbCAN_4 -0.229418172 0.13684940
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -0.193487148 0.11422628
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -0.302245305 0.05255473
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -0.201636362 0.13073212
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 -0.118005676 0.19055011
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 -0.159190274 0.20847661
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 -0.121787991 0.21058049
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 -0.152711981 0.15584380
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 -0.211418222 0.15345035
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 -0.166130021 0.16623846
## All:CUPP-Eukaryote:dbCAN_4 -0.221676861 0.08774136
## Bacteria:CUPP-Eukaryote:dbCAN_4 -0.252185488 0.11548140
## Eukaryote:CUPP-Eukaryote:dbCAN_4 -0.237682966 0.09622072
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:HMMER -0.251122812 0.08069311
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:HMMER -0.149678395 0.15803503
## All:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER -0.065009921 0.21681522
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER -0.108496242 0.23704345
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER -0.069830024 0.23788340
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER -0.099716226 0.18210892
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER -0.160633837 0.18192684
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER -0.114172054 0.19354137
## All:CUPP-All:dbCAN_4:HMMER -0.168721876 0.11404725
## Bacteria:CUPP-All:dbCAN_4:HMMER -0.201491456 0.14404824
## Eukaryote:CUPP-All:dbCAN_4:HMMER -0.185786184 0.12358481
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:HMMER -0.088006845 0.26679319
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER -0.005181115 0.32741612
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER -0.044543235 0.34352015
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER -0.008158474 0.34664156
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER -0.039887419 0.29270982
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER -0.096845241 0.28856795
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER -0.052500505 0.30229953
## All:CUPP-Bacteria:dbCAN_4:HMMER -0.108821207 0.22457628
## Bacteria:CUPP-Bacteria:dbCAN_4:HMMER -0.137538449 0.25052494
## Eukaryote:CUPP-Bacteria:dbCAN_4:HMMER -0.124005122 0.23223345
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER -0.082553556 0.22600223
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER -0.123738155 0.24392873
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER -0.086335871 0.24603261
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER -0.117259861 0.19129592
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER -0.175966102 0.18890247
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER -0.130677902 0.20169058
## All:CUPP-Eukaryote:dbCAN_4:HMMER -0.186224741 0.12319348
## Bacteria:CUPP-Eukaryote:dbCAN_4:HMMER -0.216733369 0.15093352
## Eukaryote:CUPP-Eukaryote:dbCAN_4:HMMER -0.202230846 0.13167284
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND -0.184774073 0.16151598
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND -0.146153855 0.16240193
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND -0.176078626 0.10666602
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND -0.236914924 0.10640263
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND -0.190495886 0.11805990
## All:CUPP-All:dbCAN_4:DIAMOND -0.245082746 0.03860281
## Bacteria:CUPP-All:dbCAN_4:DIAMOND -0.277769287 0.06852076
## Eukaryote:CUPP-All:dbCAN_4:DIAMOND -0.262107765 0.04810108
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:DIAMOND -0.164080358 0.20358653
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND -0.196222283 0.15006777
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND -0.252272015 0.14501781
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND -0.208422389 0.15924450
## All:CUPP-Bacteria:dbCAN_4:DIAMOND -0.265140285 0.08191845
## Bacteria:CUPP-Bacteria:dbCAN_4:DIAMOND -0.292925868 0.10693544
## Eukaryote:CUPP-Bacteria:dbCAN_4:DIAMOND -0.279901931 0.08915335
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND -0.197108233 0.11144755
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND -0.255814473 0.10905410
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND -0.210526273 0.12184221
## All:CUPP-Eukaryote:dbCAN_4:DIAMOND -0.266073113 0.04334511
## Bacteria:CUPP-Eukaryote:dbCAN_4:DIAMOND -0.296581740 0.07108514
## Eukaryote:CUPP-Eukaryote:dbCAN_4:DIAMOND -0.282079217 0.05182446
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub -0.202208619 0.14110893
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub -0.155789581 0.15276620
## All:CUPP-All:dbCAN_4:dbCAN-sub -0.210376441 0.07330912
## Bacteria:CUPP-All:dbCAN_4:dbCAN-sub -0.243062982 0.10322707
## Eukaryote:CUPP-All:dbCAN_4:dbCAN-sub -0.227401461 0.08280739
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:dbCAN-sub -0.153396134 0.21147244
## All:CUPP-Bacteria:dbCAN_4:dbCAN-sub -0.210030253 0.13406262
## Bacteria:CUPP-Bacteria:dbCAN_4:dbCAN-sub -0.238013026 0.15927680
## Eukaryote:CUPP-Bacteria:dbCAN_4:dbCAN-sub -0.224880980 0.14138660
## All:CUPP-Eukaryote:dbCAN_4:dbCAN-sub -0.221731082 0.08768714
## Bacteria:CUPP-Eukaryote:dbCAN_4:dbCAN-sub -0.252239709 0.11542718
## Eukaryote:CUPP-Eukaryote:dbCAN_4:dbCAN-sub -0.237737187 0.09616650
## Bacteria:CUPP-All:CUPP -0.174913661 0.17214507
## Eukaryote:CUPP-All:CUPP -0.159296726 0.15176998
## Eukaryote:CUPP-Bacteria:CUPP -0.186906717 0.18214856
## p adj
## Bacteria:dbCAN_4-All:dbCAN_4 0.9999999
## Eukaryote:dbCAN_4-All:dbCAN_4 1.0000000
## All:dbCAN_4:HMMER-All:dbCAN_4 0.9995725
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4 0.3701598
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4 0.9999578
## All:dbCAN_4:DIAMOND-All:dbCAN_4 0.9999672
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4 1.0000000
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4 0.9998478
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4 1.0000000
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4 0.9999990
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4 1.0000000
## All:CUPP-All:dbCAN_4 0.9436879
## Bacteria:CUPP-All:dbCAN_4 0.9881899
## Eukaryote:CUPP-All:dbCAN_4 0.9580224
## Eukaryote:dbCAN_4-Bacteria:dbCAN_4 1.0000000
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4 1.0000000
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4 0.9086799
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4 1.0000000
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 0.9971834
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 0.9999531
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 0.9945284
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 0.9999999
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 1.0000000
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 1.0000000
## All:CUPP-Bacteria:dbCAN_4 0.9999530
## Bacteria:CUPP-Bacteria:dbCAN_4 0.9999882
## Eukaryote:CUPP-Bacteria:dbCAN_4 0.9999384
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4 0.9999225
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4 0.5201059
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4 0.9999925
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 0.9999746
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 1.0000000
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 0.9998801
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 1.0000000
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 0.9999998
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 1.0000000
## All:CUPP-Eukaryote:dbCAN_4 0.9797624
## Bacteria:CUPP-Eukaryote:dbCAN_4 0.9952878
## Eukaryote:CUPP-Eukaryote:dbCAN_4 0.9833467
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:HMMER 0.9176835
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:HMMER 1.0000000
## All:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER 0.8845294
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER 0.9952615
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER 0.8731939
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER 0.9996552
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER 1.0000000
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER 0.9999212
## All:CUPP-All:dbCAN_4:HMMER 0.9999978
## Bacteria:CUPP-All:dbCAN_4:HMMER 0.9999997
## Eukaryote:CUPP-All:dbCAN_4:HMMER 0.9999964
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:HMMER 0.9286234
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER 0.0690681
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER 0.3573830
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER 0.0800887
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER 0.3810131
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER 0.9353133
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER 0.5193243
## All:CUPP-Bacteria:dbCAN_4:HMMER 0.9976848
## Bacteria:CUPP-Bacteria:dbCAN_4:HMMER 0.9996712
## Eukaryote:CUPP-Bacteria:dbCAN_4:HMMER 0.9994651
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER 0.9624129
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER 0.9987900
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER 0.9507630
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER 0.9999673
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER 1.0000000
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER 0.9999923
## All:CUPP-Eukaryote:dbCAN_4:HMMER 0.9999958
## Bacteria:CUPP-Eukaryote:dbCAN_4:HMMER 0.9999992
## Eukaryote:CUPP-Eukaryote:dbCAN_4:HMMER 0.9999933
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND 1.0000000
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND 1.0000000
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND 0.9999567
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND 0.9941089
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND 0.9999750
## All:CUPP-All:dbCAN_4:DIAMOND 0.4591339
## Bacteria:CUPP-All:dbCAN_4:DIAMOND 0.7640156
## Eukaryote:CUPP-All:dbCAN_4:DIAMOND 0.5556687
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:DIAMOND 1.0000000
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND 1.0000000
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND 0.9998642
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND 1.0000000
## All:CUPP-Bacteria:dbCAN_4:DIAMOND 0.8996279
## Bacteria:CUPP-Bacteria:dbCAN_4:DIAMOND 0.9622548
## Eukaryote:CUPP-Bacteria:dbCAN_4:DIAMOND 0.9138123
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND 0.9998111
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND 0.9897629
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND 0.9998818
## All:CUPP-Eukaryote:dbCAN_4:DIAMOND 0.4792468
## Bacteria:CUPP-Eukaryote:dbCAN_4:DIAMOND 0.7439893
## Eukaryote:CUPP-Eukaryote:dbCAN_4:DIAMOND 0.5564260
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub 0.9999993
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub 1.0000000
## All:CUPP-All:dbCAN_4:dbCAN-sub 0.9485158
## Bacteria:CUPP-All:dbCAN_4:dbCAN-sub 0.9893710
## Eukaryote:CUPP-All:dbCAN_4:dbCAN-sub 0.9615862
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:dbCAN-sub 0.9999998
## All:CUPP-Bacteria:dbCAN_4:dbCAN-sub 0.9999884
## Bacteria:CUPP-Bacteria:dbCAN_4:dbCAN-sub 0.9999970
## Eukaryote:CUPP-Bacteria:dbCAN_4:dbCAN-sub 0.9999827
## All:CUPP-Eukaryote:dbCAN_4:dbCAN-sub 0.9796147
## Bacteria:CUPP-Eukaryote:dbCAN_4:dbCAN-sub 0.9952497
## Eukaryote:CUPP-Eukaryote:dbCAN_4:dbCAN-sub 0.9832294
## Bacteria:CUPP-All:CUPP 1.0000000
## Eukaryote:CUPP-All:CUPP 1.0000000
## Eukaryote:CUPP-Bacteria:CUPP 1.0000000## Df Sum Sq Mean Sq F value Pr(>F)
## Tax_group 2 0.058 0.0292 0.444 0.642
## Prediction_tool 4 1.681 0.4204 6.394 6.49e-05 ***
## Tax_group:Prediction_tool 8 0.031 0.0039 0.059 1.000
## Residuals 250 16.435 0.0657
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1## Df Sum Sq Mean Sq F value Pr(>F)
## Tax_group 2 0.176 0.08815 0.800 0.4504
## Prediction_tool 4 0.912 0.22797 2.070 0.0857 .
## Tax_group:Prediction_tool 8 0.090 0.01123 0.102 0.9991
## Residuals 219 24.116 0.11012
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistic_value ~ Tax_group * Prediction_tool, data = all.df.stat.ce)
##
## $`Tax_group:Prediction_tool`
## diff lwr
## Bacteria:dbCAN_4-All:dbCAN_4 4.998209e-02 -0.3480157
## Eukaryote:dbCAN_4-All:dbCAN_4 -5.614837e-02 -0.4541462
## All:dbCAN_4:HMMER-All:dbCAN_4 -1.093052e-02 -0.3904065
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4 4.197632e-02 -0.3560215
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4 -6.384397e-02 -0.4618418
## All:dbCAN_4:DIAMOND-All:dbCAN_4 1.026561e-01 -0.2823600
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4 1.046835e-01 -0.2933143
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4 1.077355e-01 -0.3066251
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4 3.387534e-05 -0.3794421
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4 4.998209e-02 -0.3480157
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4 -5.608896e-02 -0.4540868
## All:CUPP-All:dbCAN_4 -1.135126e-01 -0.4985288
## Bacteria:CUPP-All:dbCAN_4 -7.562229e-02 -0.4736201
## Eukaryote:CUPP-All:dbCAN_4 -9.609520e-02 -0.5104559
## Eukaryote:dbCAN_4-Bacteria:dbCAN_4 -1.061305e-01 -0.5218256
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4 -6.091261e-02 -0.4589104
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4 -8.005772e-03 -0.4237009
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4 -1.138261e-01 -0.5295212
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 5.267399e-02 -0.3506095
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 5.470143e-02 -0.3609937
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 5.775342e-02 -0.3736338
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 -4.994821e-02 -0.4479460
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 3.330669e-16 -0.4156952
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 -1.060710e-01 -0.5217662
## All:CUPP-Bacteria:dbCAN_4 -1.634947e-01 -0.5667783
## Bacteria:CUPP-Bacteria:dbCAN_4 -1.256044e-01 -0.5412995
## Eukaryote:CUPP-Bacteria:dbCAN_4 -1.460773e-01 -0.5774645
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4 4.521785e-02 -0.3527800
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4 9.812469e-02 -0.3175705
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -7.695600e-03 -0.4233908
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 1.588045e-01 -0.2444791
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 1.608319e-01 -0.2548633
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 1.638839e-01 -0.2675034
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 5.618225e-02 -0.3418156
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 1.061305e-01 -0.3095647
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 5.941771e-05 -0.4156357
## All:CUPP-Eukaryote:dbCAN_4 -5.736427e-02 -0.4606478
## Bacteria:CUPP-Eukaryote:dbCAN_4 -1.947392e-02 -0.4351691
## Eukaryote:CUPP-Eukaryote:dbCAN_4 -3.994683e-02 -0.4713341
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:HMMER 5.290684e-02 -0.3450910
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:HMMER -5.291345e-02 -0.4509113
## All:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER 1.135866e-01 -0.2714295
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER 1.156140e-01 -0.2823838
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER 1.186660e-01 -0.2956946
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER 1.096440e-02 -0.3685116
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER 6.091261e-02 -0.3370852
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER -4.515844e-02 -0.4431562
## All:CUPP-All:dbCAN_4:HMMER -1.025821e-01 -0.4875982
## Bacteria:CUPP-All:dbCAN_4:HMMER -6.469177e-02 -0.4626896
## Eukaryote:CUPP-All:dbCAN_4:HMMER -8.516468e-02 -0.4995253
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:HMMER -1.058203e-01 -0.5215154
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER 6.067976e-02 -0.3426038
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER 6.270721e-02 -0.3529879
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER 6.575919e-02 -0.3656281
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER -4.194244e-02 -0.4399402
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER 8.005772e-03 -0.4076894
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER -9.806527e-02 -0.5137604
## All:CUPP-Bacteria:dbCAN_4:HMMER -1.554890e-01 -0.5587725
## Bacteria:CUPP-Bacteria:dbCAN_4:HMMER -1.175986e-01 -0.5332938
## Eukaryote:CUPP-Bacteria:dbCAN_4:HMMER -1.380715e-01 -0.5694588
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER 1.665001e-01 -0.2367835
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER 1.685275e-01 -0.2471677
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER 1.715795e-01 -0.2598078
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER 6.387785e-02 -0.3341200
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER 1.138261e-01 -0.3018691
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER 7.755018e-03 -0.4079401
## All:CUPP-Eukaryote:dbCAN_4:HMMER -4.966867e-02 -0.4529522
## Bacteria:CUPP-Eukaryote:dbCAN_4:HMMER -1.177832e-02 -0.4274735
## Eukaryote:CUPP-Eukaryote:dbCAN_4:HMMER -3.225123e-02 -0.4636385
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND 2.027445e-03 -0.4012561
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND 5.079433e-03 -0.4143608
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND -1.026222e-01 -0.4876383
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND -5.267399e-02 -0.4559575
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND -1.587450e-01 -0.5620286
## All:CUPP-All:dbCAN_4:DIAMOND -2.161687e-01 -0.6066463
## Bacteria:CUPP-All:dbCAN_4:DIAMOND -1.782784e-01 -0.5815619
## Eukaryote:CUPP-All:dbCAN_4:DIAMOND -1.987513e-01 -0.6181915
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:DIAMOND 3.051987e-03 -0.4283353
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND -1.046496e-01 -0.5026475
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND -5.470143e-02 -0.4703966
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND -1.607725e-01 -0.5764676
## All:CUPP-Bacteria:dbCAN_4:DIAMOND -2.181962e-01 -0.6214797
## Bacteria:CUPP-Bacteria:dbCAN_4:DIAMOND -1.803058e-01 -0.5960010
## Eukaryote:CUPP-Bacteria:dbCAN_4:DIAMOND -2.007787e-01 -0.6321660
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND -1.077016e-01 -0.5220623
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND -5.775342e-02 -0.4891407
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND -1.638245e-01 -0.5952117
## All:CUPP-Eukaryote:dbCAN_4:DIAMOND -2.212482e-01 -0.6406884
## Bacteria:CUPP-Eukaryote:dbCAN_4:DIAMOND -1.833578e-01 -0.6147451
## Eukaryote:CUPP-Eukaryote:dbCAN_4:DIAMOND -2.038307e-01 -0.6503589
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub 4.994821e-02 -0.3480496
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub -5.612283e-02 -0.4541206
## All:CUPP-All:dbCAN_4:dbCAN-sub -1.135465e-01 -0.4985626
## Bacteria:CUPP-All:dbCAN_4:dbCAN-sub -7.565617e-02 -0.4736540
## Eukaryote:CUPP-All:dbCAN_4:dbCAN-sub -9.612908e-02 -0.5104897
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:dbCAN-sub -1.060710e-01 -0.5217662
## All:CUPP-Bacteria:dbCAN_4:dbCAN-sub -1.634947e-01 -0.5667783
## Bacteria:CUPP-Bacteria:dbCAN_4:dbCAN-sub -1.256044e-01 -0.5412995
## Eukaryote:CUPP-Bacteria:dbCAN_4:dbCAN-sub -1.460773e-01 -0.5774645
## All:CUPP-Eukaryote:dbCAN_4:dbCAN-sub -5.742369e-02 -0.4607072
## Bacteria:CUPP-Eukaryote:dbCAN_4:dbCAN-sub -1.953334e-02 -0.4352285
## Eukaryote:CUPP-Eukaryote:dbCAN_4:dbCAN-sub -4.000625e-02 -0.4713935
## Bacteria:CUPP-All:CUPP 3.789035e-02 -0.3653932
## Eukaryote:CUPP-All:CUPP 1.741744e-02 -0.4020228
## Eukaryote:CUPP-Bacteria:CUPP -2.047291e-02 -0.4518602
## upr p adj
## Bacteria:dbCAN_4-All:dbCAN_4 0.4479799 1.0000000
## Eukaryote:dbCAN_4-All:dbCAN_4 0.3418494 1.0000000
## All:dbCAN_4:HMMER-All:dbCAN_4 0.3685455 1.0000000
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4 0.4399741 1.0000000
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4 0.3341538 0.9999998
## All:dbCAN_4:DIAMOND-All:dbCAN_4 0.4876722 0.9998577
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4 0.5026813 0.9998789
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4 0.5220962 0.9998944
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4 0.3795099 1.0000000
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4 0.4479799 1.0000000
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4 0.3419089 1.0000000
## All:CUPP-All:dbCAN_4 0.2715035 0.9995443
## Bacteria:CUPP-All:dbCAN_4 0.3223755 0.9999978
## Eukaryote:CUPP-All:dbCAN_4 0.3182655 0.9999736
## Eukaryote:dbCAN_4-Bacteria:dbCAN_4 0.3095647 0.9999150
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4 0.3370852 0.9999999
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4 0.4076894 1.0000000
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4 0.3018691 0.9998055
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 0.4559575 1.0000000
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 0.4703966 1.0000000
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 0.4891407 1.0000000
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 0.3480496 1.0000000
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 0.4156952 1.0000000
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 0.3096241 0.9999156
## All:CUPP-Bacteria:dbCAN_4 0.2397888 0.9874059
## Bacteria:CUPP-Bacteria:dbCAN_4 0.2900908 0.9993987
## Eukaryote:CUPP-Bacteria:dbCAN_4 0.2853100 0.9979140
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4 0.4432157 1.0000000
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4 0.5138198 0.9999671
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4 0.4079996 1.0000000
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 0.5620880 0.9904332
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 0.5765270 0.9919259
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 0.5952711 0.9932433
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 0.4541801 1.0000000
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 0.5218256 0.9999150
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 0.4157546 1.0000000
## All:CUPP-Eukaryote:dbCAN_4 0.3459193 1.0000000
## Bacteria:CUPP-Eukaryote:dbCAN_4 0.3962212 1.0000000
## Eukaryote:CUPP-Eukaryote:dbCAN_4 0.3914404 1.0000000
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:HMMER 0.4509046 1.0000000
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:HMMER 0.3450844 1.0000000
## All:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER 0.4986027 0.9995409
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER 0.5136118 0.9996150
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER 0.5330267 0.9996729
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER 0.3904404 1.0000000
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER 0.4589104 0.9999999
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER 0.3528394 1.0000000
## All:CUPP-All:dbCAN_4:HMMER 0.2824340 0.9998589
## Bacteria:CUPP-All:dbCAN_4:HMMER 0.3333060 0.9999997
## Eukaryote:CUPP-All:dbCAN_4:HMMER 0.3291960 0.9999941
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:HMMER 0.3098749 0.9999180
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER 0.4639633 0.9999999
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER 0.4784024 0.9999999
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER 0.4971464 0.9999999
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER 0.3560554 1.0000000
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER 0.4237009 1.0000000
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER 0.3176299 0.9999674
## All:CUPP-Bacteria:dbCAN_4:HMMER 0.2477946 0.9921934
## Bacteria:CUPP-Bacteria:dbCAN_4:HMMER 0.2980965 0.9997159
## Eukaryote:CUPP-Bacteria:dbCAN_4:HMMER 0.2933157 0.9988623
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER 0.5697836 0.9850924
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER 0.5842226 0.9874053
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER 0.6029667 0.9894771
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER 0.4618757 0.9999998
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER 0.5295212 0.9998055
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER 0.4234502 1.0000000
## All:CUPP-Eukaryote:dbCAN_4:HMMER 0.3536149 1.0000000
## Bacteria:CUPP-Eukaryote:dbCAN_4:HMMER 0.4039168 1.0000000
## Eukaryote:CUPP-Eukaryote:dbCAN_4:HMMER 0.3991360 1.0000000
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND 0.4053110 1.0000000
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND 0.4245197 1.0000000
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND 0.2823939 0.9998583
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND 0.3506095 1.0000000
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND 0.2445385 0.9904674
## All:CUPP-All:dbCAN_4:DIAMOND 0.1743089 0.8511744
## Bacteria:CUPP-All:dbCAN_4:DIAMOND 0.2250052 0.9726099
## Eukaryote:CUPP-All:dbCAN_4:DIAMOND 0.2206889 0.9512972
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:DIAMOND 0.4344392 1.0000000
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND 0.2933482 0.9998793
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND 0.3609937 1.0000000
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND 0.2549227 0.9919548
## All:CUPP-Bacteria:dbCAN_4:DIAMOND 0.1850874 0.8717399
## Bacteria:CUPP-Bacteria:dbCAN_4:DIAMOND 0.2353893 0.9767791
## Eukaryote:CUPP-Bacteria:dbCAN_4:DIAMOND 0.2306085 0.9578460
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND 0.3066590 0.9998948
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND 0.3736338 1.0000000
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND 0.2675628 0.9932673
## All:CUPP-Eukaryote:dbCAN_4:DIAMOND 0.1981921 0.8919302
## Bacteria:CUPP-Eukaryote:dbCAN_4:DIAMOND 0.2480294 0.9805958
## Eukaryote:CUPP-Eukaryote:dbCAN_4:DIAMOND 0.2426975 0.9640671
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub 0.4479460 1.0000000
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub 0.3418750 1.0000000
## All:CUPP-All:dbCAN_4:dbCAN-sub 0.2714696 0.9995427
## Bacteria:CUPP-All:dbCAN_4:dbCAN-sub 0.3223416 0.9999978
## Eukaryote:CUPP-All:dbCAN_4:dbCAN-sub 0.3182316 0.9999734
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:dbCAN-sub 0.3096241 0.9999156
## All:CUPP-Bacteria:dbCAN_4:dbCAN-sub 0.2397888 0.9874059
## Bacteria:CUPP-Bacteria:dbCAN_4:dbCAN-sub 0.2900908 0.9993987
## Eukaryote:CUPP-Bacteria:dbCAN_4:dbCAN-sub 0.2853100 0.9979140
## All:CUPP-Eukaryote:dbCAN_4:dbCAN-sub 0.3458598 1.0000000
## Bacteria:CUPP-Eukaryote:dbCAN_4:dbCAN-sub 0.3961618 1.0000000
## Eukaryote:CUPP-Eukaryote:dbCAN_4:dbCAN-sub 0.3913810 1.0000000
## Bacteria:CUPP-All:CUPP 0.4411739 1.0000000
## Eukaryote:CUPP-All:CUPP 0.4368577 1.0000000
## Eukaryote:CUPP-Bacteria:CUPP 0.4109143 1.0000000## Df Sum Sq Mean Sq F value Pr(>F)
## Tax_group 2 0.144 0.07203 0.904 0.4072
## Prediction_tool 4 1.067 0.26673 3.347 0.0118 *
## Tax_group:Prediction_tool 8 0.041 0.00514 0.065 0.9998
## Residuals 145 11.554 0.07968
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1## Df Sum Sq Mean Sq F value Pr(>F)
## Tax_group 2 0.00 0.002 0.016 0.984
## Prediction_tool 4 65.44 16.360 173.567 <2e-16 ***
## Tax_group:Prediction_tool 8 0.47 0.059 0.623 0.759
## Residuals 619 58.35 0.094
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Statistic_value ~ Tax_group * Prediction_tool, data = all.df.stat.cbm)
##
## $`Tax_group:Prediction_tool`
## diff
## Bacteria:dbCAN_4-All:dbCAN_4 -1.330733e-03
## Eukaryote:dbCAN_4-All:dbCAN_4 3.129059e-02
## All:dbCAN_4:HMMER-All:dbCAN_4 -7.950945e-02
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4 -6.451772e-02
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4 -1.881683e-01
## All:dbCAN_4:DIAMOND-All:dbCAN_4 4.375204e-02
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4 2.126428e-02
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4 1.179353e-01
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4 -3.116907e-02
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4 -1.526988e-03
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4 -3.408568e-02
## All:CUPP-All:dbCAN_4 -8.143693e-01
## Bacteria:CUPP-All:dbCAN_4 -8.143693e-01
## Eukaryote:CUPP-All:dbCAN_4 -8.143693e-01
## Eukaryote:dbCAN_4-Bacteria:dbCAN_4 3.262132e-02
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4 -7.817871e-02
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4 -6.318699e-02
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4 -1.868375e-01
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 4.508278e-02
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 2.259501e-02
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 1.192661e-01
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 -2.983834e-02
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 -1.962551e-04
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 -3.275495e-02
## All:CUPP-Bacteria:dbCAN_4 -8.130385e-01
## Bacteria:CUPP-Bacteria:dbCAN_4 -8.130385e-01
## Eukaryote:CUPP-Bacteria:dbCAN_4 -8.130385e-01
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -1.108000e-01
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -9.580831e-02
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -2.194588e-01
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 1.246145e-02
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 -1.002631e-02
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 8.664474e-02
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 -6.245967e-02
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 -3.281758e-02
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 -6.537627e-02
## All:CUPP-Eukaryote:dbCAN_4 -8.456599e-01
## Bacteria:CUPP-Eukaryote:dbCAN_4 -8.456599e-01
## Eukaryote:CUPP-Eukaryote:dbCAN_4 -8.456599e-01
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:HMMER 1.499173e-02
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:HMMER -1.086588e-01
## All:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER 1.232615e-01
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER 1.007737e-01
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER 1.974448e-01
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER 4.834037e-02
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER 7.798246e-02
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER 4.542376e-02
## All:CUPP-All:dbCAN_4:HMMER -7.348598e-01
## Bacteria:CUPP-All:dbCAN_4:HMMER -7.348598e-01
## Eukaryote:CUPP-All:dbCAN_4:HMMER -7.348598e-01
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:HMMER -1.236505e-01
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER 1.082698e-01
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER 8.578200e-02
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER 1.824531e-01
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER 3.334864e-02
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER 6.299073e-02
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER 3.043204e-02
## All:CUPP-Bacteria:dbCAN_4:HMMER -7.498516e-01
## Bacteria:CUPP-Bacteria:dbCAN_4:HMMER -7.498516e-01
## Eukaryote:CUPP-Bacteria:dbCAN_4:HMMER -7.498516e-01
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER 2.319203e-01
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER 2.094325e-01
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER 3.061036e-01
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER 1.569992e-01
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER 1.866413e-01
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER 1.540826e-01
## All:CUPP-Eukaryote:dbCAN_4:HMMER -6.262010e-01
## Bacteria:CUPP-Eukaryote:dbCAN_4:HMMER -6.262010e-01
## Eukaryote:CUPP-Eukaryote:dbCAN_4:HMMER -6.262010e-01
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND -2.248776e-02
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND 7.418329e-02
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND -7.492112e-02
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND -4.527903e-02
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND -7.783773e-02
## All:CUPP-All:dbCAN_4:DIAMOND -8.581213e-01
## Bacteria:CUPP-All:dbCAN_4:DIAMOND -8.581213e-01
## Eukaryote:CUPP-All:dbCAN_4:DIAMOND -8.581213e-01
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:DIAMOND 9.667105e-02
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND -5.243335e-02
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND -2.279127e-02
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND -5.534996e-02
## All:CUPP-Bacteria:dbCAN_4:DIAMOND -8.356336e-01
## Bacteria:CUPP-Bacteria:dbCAN_4:DIAMOND -8.356336e-01
## Eukaryote:CUPP-Bacteria:dbCAN_4:DIAMOND -8.356336e-01
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND -1.491044e-01
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND -1.194623e-01
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND -1.520210e-01
## All:CUPP-Eukaryote:dbCAN_4:DIAMOND -9.323046e-01
## Bacteria:CUPP-Eukaryote:dbCAN_4:DIAMOND -9.323046e-01
## Eukaryote:CUPP-Eukaryote:dbCAN_4:DIAMOND -9.323046e-01
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub 2.964209e-02
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub -2.916609e-03
## All:CUPP-All:dbCAN_4:dbCAN-sub -7.832002e-01
## Bacteria:CUPP-All:dbCAN_4:dbCAN-sub -7.832002e-01
## Eukaryote:CUPP-All:dbCAN_4:dbCAN-sub -7.832002e-01
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:dbCAN-sub -3.255870e-02
## All:CUPP-Bacteria:dbCAN_4:dbCAN-sub -8.128423e-01
## Bacteria:CUPP-Bacteria:dbCAN_4:dbCAN-sub -8.128423e-01
## Eukaryote:CUPP-Bacteria:dbCAN_4:dbCAN-sub -8.128423e-01
## All:CUPP-Eukaryote:dbCAN_4:dbCAN-sub -7.802836e-01
## Bacteria:CUPP-Eukaryote:dbCAN_4:dbCAN-sub -7.802836e-01
## Eukaryote:CUPP-Eukaryote:dbCAN_4:dbCAN-sub -7.802836e-01
## Bacteria:CUPP-All:CUPP 4.597017e-16
## Eukaryote:CUPP-All:CUPP 4.961309e-16
## Eukaryote:CUPP-Bacteria:CUPP 3.642919e-17
## lwr upr
## Bacteria:dbCAN_4-All:dbCAN_4 -0.208142210 0.20548074
## Eukaryote:dbCAN_4-All:dbCAN_4 -0.220174357 0.28275554
## All:dbCAN_4:HMMER-All:dbCAN_4 -0.277078969 0.11806008
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4 -0.271329196 0.14229376
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4 -0.439633207 0.06329669
## All:dbCAN_4:DIAMOND-All:dbCAN_4 -0.154713492 0.24221758
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4 -0.186765794 0.22929435
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4 -0.137125823 0.37299649
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4 -0.228738597 0.16640045
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4 -0.208338465 0.20528449
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4 -0.285550632 0.21737927
## All:CUPP-All:dbCAN_4 -1.012834808 -0.61590374
## Bacteria:CUPP-All:dbCAN_4 -1.022399347 -0.60633920
## Eukaryote:CUPP-All:dbCAN_4 -1.069430430 -0.55930812
## Eukaryote:dbCAN_4-Bacteria:dbCAN_4 -0.226167955 0.29141060
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4 -0.284990190 0.12863276
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4 -0.278844719 0.15247075
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4 -0.445626805 0.07195175
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 -0.162584841 0.25275039
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 -0.194231606 0.23942163
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 -0.143019016 0.38155115
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 -0.236649818 0.17697314
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 -0.215853988 0.21546148
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 -0.291544230 0.22603433
## All:CUPP-Bacteria:dbCAN_4 -1.020706157 -0.60537092
## Bacteria:CUPP-Bacteria:dbCAN_4 -1.029865158 -0.59621192
## Eukaryote:CUPP-Bacteria:dbCAN_4 -1.075323623 -0.55075346
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -0.362264987 0.14066491
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -0.354597590 0.16298097
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -0.515153836 0.07623614
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 -0.239708081 0.26463098
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 -0.269790466 0.24973784
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 -0.212114522 0.38540401
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 -0.313924615 0.18900528
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 -0.291606860 0.22597170
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 -0.361071261 0.23031871
## All:CUPP-Eukaryote:dbCAN_4 -1.097829396 -0.59349033
## Bacteria:CUPP-Eukaryote:dbCAN_4 -1.105424019 -0.58589571
## Eukaryote:CUPP-Eukaryote:dbCAN_4 -1.144419130 -0.54690060
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:HMMER -0.191819750 0.22180320
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:HMMER -0.360123761 0.14280614
## All:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER -0.075204046 0.32172702
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER -0.107256348 0.30880380
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER -0.057616377 0.45250594
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER -0.149229151 0.24590990
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER -0.128829019 0.28479394
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER -0.206041186 0.29688871
## All:CUPP-All:dbCAN_4:HMMER -0.933325362 -0.53639429
## Bacteria:CUPP-All:dbCAN_4:HMMER -0.942889901 -0.52682975
## Eukaryote:CUPP-All:dbCAN_4:HMMER -0.989920985 -0.47979867
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:HMMER -0.382439819 0.13513874
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER -0.099397856 0.31593738
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER -0.131044620 0.30260862
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER -0.079832030 0.44473814
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER -0.173462832 0.24016012
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER -0.152667002 0.27864846
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER -0.228357244 0.28922132
## All:CUPP-Bacteria:dbCAN_4:HMMER -0.957519171 -0.54218394
## Bacteria:CUPP-Bacteria:dbCAN_4:HMMER -0.966678173 -0.53302494
## Eukaryote:CUPP-Bacteria:dbCAN_4:HMMER -1.012136637 -0.48756647
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER -0.020249231 0.48408983
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER -0.050331617 0.46919669
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER 0.007344328 0.60486286
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER -0.094465765 0.40846413
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER -0.072148010 0.44543055
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER -0.141612411 0.44977756
## All:CUPP-Eukaryote:dbCAN_4:HMMER -0.878370547 -0.37403148
## Bacteria:CUPP-Eukaryote:dbCAN_4:HMMER -0.885965169 -0.36643686
## Eukaryote:CUPP-Eukaryote:dbCAN_4:HMMER -0.924960280 -0.32744175
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND -0.231368982 0.18639346
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND -0.181572541 0.32993912
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND -0.273386651 0.12354442
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND -0.252946647 0.16238859
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND -0.330007257 0.17433181
## All:CUPP-All:dbCAN_4:DIAMOND -1.057478835 -0.65876380
## Bacteria:CUPP-All:dbCAN_4:DIAMOND -1.067002535 -0.64924010
## Eukaryote:CUPP-All:dbCAN_4:DIAMOND -1.113877148 -0.60236548
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:DIAMOND -0.166575957 0.35991807
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND -0.260463427 0.15559672
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND -0.239617886 0.19403535
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND -0.315114117 0.20441419
## All:CUPP-Bacteria:dbCAN_4:DIAMOND -1.044514772 -0.62675233
## Bacteria:CUPP-Bacteria:dbCAN_4:DIAMOND -1.053622789 -0.61764432
## Eukaryote:CUPP-Bacteria:dbCAN_4:DIAMOND -1.098880565 -0.57238654
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND -0.404165565 0.10595675
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND -0.381747405 0.14282276
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND -0.450780282 0.14673825
## All:CUPP-Eukaryote:dbCAN_4:DIAMOND -1.188060440 -0.67654877
## Bacteria:CUPP-Eukaryote:dbCAN_4:DIAMOND -1.195551619 -0.66905760
## Eukaryote:CUPP-Eukaryote:dbCAN_4:DIAMOND -1.234097039 -0.63051218
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub -0.177169391 0.23645356
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub -0.254381558 0.24854834
## All:CUPP-All:dbCAN_4:dbCAN-sub -0.981665734 -0.58473466
## Bacteria:CUPP-All:dbCAN_4:dbCAN-sub -0.991230273 -0.57517013
## Eukaryote:CUPP-All:dbCAN_4:dbCAN-sub -1.038261357 -0.52813904
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:dbCAN-sub -0.291347975 0.22623058
## All:CUPP-Bacteria:dbCAN_4:dbCAN-sub -1.020509902 -0.60517467
## Bacteria:CUPP-Bacteria:dbCAN_4:dbCAN-sub -1.029668903 -0.59601567
## Eukaryote:CUPP-Bacteria:dbCAN_4:dbCAN-sub -1.075127368 -0.55055720
## All:CUPP-Eukaryote:dbCAN_4:dbCAN-sub -1.032453121 -0.52811406
## Bacteria:CUPP-Eukaryote:dbCAN_4:dbCAN-sub -1.040047744 -0.52051944
## Eukaryote:CUPP-Eukaryote:dbCAN_4:dbCAN-sub -1.079042855 -0.48152433
## Bacteria:CUPP-All:CUPP -0.208881219 0.20888122
## Eukaryote:CUPP-All:CUPP -0.255755833 0.25575583
## Eukaryote:CUPP-Bacteria:CUPP -0.263247012 0.26324701
## p adj
## Bacteria:dbCAN_4-All:dbCAN_4 1.0000000
## Eukaryote:dbCAN_4-All:dbCAN_4 1.0000000
## All:dbCAN_4:HMMER-All:dbCAN_4 0.9895365
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4 0.9992631
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4 0.4076652
## All:dbCAN_4:DIAMOND-All:dbCAN_4 0.9999883
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4 1.0000000
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4 0.9635977
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4 0.9999998
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4 1.0000000
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4 1.0000000
## All:CUPP-All:dbCAN_4 0.0000000
## Bacteria:CUPP-All:dbCAN_4 0.0000000
## Eukaryote:CUPP-All:dbCAN_4 0.0000000
## Eukaryote:dbCAN_4-Bacteria:dbCAN_4 1.0000000
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4 0.9943286
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4 0.9996381
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4 0.4722993
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 0.9999903
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 1.0000000
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 0.9683905
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 1.0000000
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 1.0000000
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 1.0000000
## All:CUPP-Bacteria:dbCAN_4 0.0000000
## Bacteria:CUPP-Bacteria:dbCAN_4 0.0000000
## Eukaryote:CUPP-Bacteria:dbCAN_4 0.0000000
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4 0.9759424
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4 0.9954042
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4 0.4223801
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 1.0000000
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 1.0000000
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 0.9996783
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 0.9999488
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 1.0000000
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 0.9999878
## All:CUPP-Eukaryote:dbCAN_4 0.0000000
## Bacteria:CUPP-Eukaryote:dbCAN_4 0.0000000
## Eukaryote:CUPP-Eukaryote:dbCAN_4 0.0000000
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:HMMER 1.0000000
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:HMMER 0.9797741
## All:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER 0.7246487
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER 0.9467898
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER 0.3479034
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER 0.9999574
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER 0.9944697
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER 0.9999991
## All:CUPP-All:dbCAN_4:HMMER 0.0000000
## Bacteria:CUPP-All:dbCAN_4:HMMER 0.0000000
## Eukaryote:CUPP-All:dbCAN_4:HMMER 0.0000000
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:HMMER 0.9523300
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER 0.9072476
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER 0.9911208
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER 0.5392344
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER 0.9999998
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER 0.9996508
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER 1.0000000
## All:CUPP-Bacteria:dbCAN_4:HMMER 0.0000000
## Bacteria:CUPP-Bacteria:dbCAN_4:HMMER 0.0000000
## Eukaryote:CUPP-Bacteria:dbCAN_4:HMMER 0.0000000
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER 0.1109084
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER 0.2801699
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER 0.0383473
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER 0.7170609
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER 0.4742030
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER 0.9075981
## All:CUPP-Eukaryote:dbCAN_4:HMMER 0.0000000
## Bacteria:CUPP-Eukaryote:dbCAN_4:HMMER 0.0000000
## Eukaryote:CUPP-Eukaryote:dbCAN_4:HMMER 0.0000000
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND 1.0000000
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND 0.9996778
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND 0.9944059
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND 0.9999898
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND 0.9993457
## All:CUPP-All:dbCAN_4:DIAMOND 0.0000000
## Bacteria:CUPP-All:dbCAN_4:DIAMOND 0.0000000
## Eukaryote:CUPP-All:dbCAN_4:DIAMOND 0.0000000
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:DIAMOND 0.9957687
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND 0.9999389
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND 1.0000000
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND 0.9999924
## All:CUPP-Bacteria:dbCAN_4:DIAMOND 0.0000000
## Bacteria:CUPP-Bacteria:dbCAN_4:DIAMOND 0.0000000
## Eukaryote:CUPP-Bacteria:dbCAN_4:DIAMOND 0.0000000
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND 0.8034602
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND 0.9679446
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND 0.9223474
## All:CUPP-Eukaryote:dbCAN_4:DIAMOND 0.0000000
## Bacteria:CUPP-Eukaryote:dbCAN_4:DIAMOND 0.0000000
## Eukaryote:CUPP-Eukaryote:dbCAN_4:DIAMOND 0.0000000
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub 1.0000000
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub 1.0000000
## All:CUPP-All:dbCAN_4:dbCAN-sub 0.0000000
## Bacteria:CUPP-All:dbCAN_4:dbCAN-sub 0.0000000
## Eukaryote:CUPP-All:dbCAN_4:dbCAN-sub 0.0000000
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:dbCAN-sub 1.0000000
## All:CUPP-Bacteria:dbCAN_4:dbCAN-sub 0.0000000
## Bacteria:CUPP-Bacteria:dbCAN_4:dbCAN-sub 0.0000000
## Eukaryote:CUPP-Bacteria:dbCAN_4:dbCAN-sub 0.0000000
## All:CUPP-Eukaryote:dbCAN_4:dbCAN-sub 0.0000000
## Bacteria:CUPP-Eukaryote:dbCAN_4:dbCAN-sub 0.0000000
## Eukaryote:CUPP-Eukaryote:dbCAN_4:dbCAN-sub 0.0000000
## Bacteria:CUPP-All:CUPP 1.0000000
## Eukaryote:CUPP-All:CUPP 1.0000000
## Eukaryote:CUPP-Bacteria:CUPP 1.000000012.2.4.2 Test for statistically significant differences in the means
## Df Sum Sq Mean Sq F value Pr(>F)
## Tax_group 2 0.9 0.468 5.075 0.00629 **
## Prediction_tool 4 38.9 9.736 105.552 < 2e-16 ***
## Tax_group:Prediction_tool 8 0.3 0.043 0.465 0.88146
## Residuals 3867 356.7 0.092
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 112.2.5 Accuracy
| Prediction_tool | Mean | Standard Deviation | LowerCI | UpperCI | Tax_group | CAZy_class |
|---|---|---|---|---|---|---|
| dbCAN_4 | 0.9997 | 0.0009 | 0.9996 | 0.9999 | All | GH |
| dbCAN_4:HMMER | 0.9996 | 0.0013 | 0.9994 | 0.9998 | All | GH |
| dbCAN_4:DIAMOND | 0.9997 | 0.0009 | 0.9996 | 0.9999 | All | GH |
| dbCAN_4:dbCAN-sub | 0.9997 | 0.0009 | 0.9996 | 0.9999 | All | GH |
| CUPP | 0.9996 | 0.0011 | 0.9994 | 0.9998 | All | GH |
| dbCAN_4 | 0.9996 | 0.0022 | 0.9991 | 1.0001 | Bacteria | GH |
| dbCAN_4:HMMER | 0.9994 | 0.0023 | 0.9989 | 0.9999 | Bacteria | GH |
| dbCAN_4:DIAMOND | 0.9998 | 0.0004 | 0.9997 | 0.9999 | Bacteria | GH |
| dbCAN_4:dbCAN-sub | 0.9996 | 0.0022 | 0.9991 | 1.0001 | Bacteria | GH |
| CUPP | 0.9994 | 0.0023 | 0.9989 | 0.9998 | Bacteria | GH |
| dbCAN_4 | 0.9998 | 0.0013 | 0.9995 | 1.0000 | Eukaryote | GH |
| dbCAN_4:HMMER | 0.9996 | 0.0014 | 0.9994 | 0.9999 | Eukaryote | GH |
| dbCAN_4:DIAMOND | 0.9998 | 0.0005 | 0.9997 | 0.9999 | Eukaryote | GH |
| dbCAN_4:dbCAN-sub | 0.9997 | 0.0013 | 0.9995 | 1.0000 | Eukaryote | GH |
| CUPP | 0.9996 | 0.0013 | 0.9994 | 0.9998 | Eukaryote | GH |
| dbCAN_4 | 0.9991 | 0.0022 | 0.9984 | 0.9998 | All | GT |
| dbCAN_4:HMMER | 0.9985 | 0.0038 | 0.9974 | 0.9997 | All | GT |
| dbCAN_4:DIAMOND | 0.9993 | 0.0013 | 0.9989 | 0.9997 | All | GT |
| dbCAN_4:dbCAN-sub | 0.9991 | 0.0022 | 0.9984 | 0.9998 | All | GT |
| CUPP | 0.9988 | 0.0031 | 0.9978 | 0.9998 | All | GT |
| dbCAN_4 | 0.9994 | 0.0015 | 0.9990 | 0.9998 | Bacteria | GT |
| dbCAN_4:HMMER | 0.9989 | 0.0023 | 0.9983 | 0.9995 | Bacteria | GT |
| dbCAN_4:DIAMOND | 0.9997 | 0.0007 | 0.9995 | 0.9998 | Bacteria | GT |
| dbCAN_4:dbCAN-sub | 0.9994 | 0.0015 | 0.9990 | 0.9998 | Bacteria | GT |
| CUPP | 0.9987 | 0.0023 | 0.9981 | 0.9993 | Bacteria | GT |
| dbCAN_4 | 0.9996 | 0.0013 | 0.9993 | 0.9999 | Eukaryote | GT |
| dbCAN_4:HMMER | 0.9992 | 0.0021 | 0.9987 | 0.9997 | Eukaryote | GT |
| dbCAN_4:DIAMOND | 0.9997 | 0.0007 | 0.9995 | 0.9999 | Eukaryote | GT |
| dbCAN_4:dbCAN-sub | 0.9996 | 0.0013 | 0.9992 | 0.9999 | Eukaryote | GT |
| CUPP | 0.9992 | 0.0018 | 0.9988 | 0.9996 | Eukaryote | GT |
| dbCAN_4 | 0.9999 | 0.0001 | 0.9999 | 1.0000 | All | PL |
| dbCAN_4:HMMER | 0.9999 | 0.0001 | 0.9999 | 1.0000 | All | PL |
| dbCAN_4:DIAMOND | 0.9999 | 0.0001 | 0.9999 | 1.0000 | All | PL |
| dbCAN_4:dbCAN-sub | 0.9999 | 0.0001 | 0.9999 | 1.0000 | All | PL |
| CUPP | 0.9998 | 0.0004 | 0.9996 | 0.9999 | All | PL |
| dbCAN_4 | 0.9999 | 0.0001 | 0.9998 | 1.0000 | Bacteria | PL |
| dbCAN_4:HMMER | 0.9999 | 0.0001 | 0.9998 | 1.0000 | Bacteria | PL |
| dbCAN_4:DIAMOND | 0.9999 | 0.0002 | 0.9997 | 1.0000 | Bacteria | PL |
| dbCAN_4:dbCAN-sub | 0.9999 | 0.0001 | 0.9998 | 1.0000 | Bacteria | PL |
| CUPP | 0.9998 | 0.0003 | 0.9996 | 1.0000 | Bacteria | PL |
| dbCAN_4 | 1.0000 | 0.0001 | 0.9999 | 1.0000 | Eukaryote | PL |
| dbCAN_4:HMMER | 1.0000 | 0.0001 | 0.9999 | 1.0000 | Eukaryote | PL |
| dbCAN_4:DIAMOND | 1.0000 | 0.0001 | 0.9999 | 1.0000 | Eukaryote | PL |
| dbCAN_4:dbCAN-sub | 1.0000 | 0.0001 | 0.9999 | 1.0000 | Eukaryote | PL |
| CUPP | 0.9999 | 0.0003 | 0.9997 | 1.0000 | Eukaryote | PL |
| dbCAN_4 | 0.9989 | 0.0021 | 0.9977 | 1.0001 | All | CE |
| dbCAN_4:HMMER | 0.9987 | 0.0023 | 0.9974 | 1.0000 | All | CE |
| dbCAN_4:DIAMOND | 0.9992 | 0.0017 | 0.9982 | 1.0001 | All | CE |
| dbCAN_4:dbCAN-sub | 0.9989 | 0.0021 | 0.9977 | 1.0001 | All | CE |
| CUPP | 0.9986 | 0.0021 | 0.9974 | 0.9998 | All | CE |
| dbCAN_4 | 0.9995 | 0.0008 | 0.9991 | 1.0000 | Bacteria | CE |
| dbCAN_4:HMMER | 0.9995 | 0.0008 | 0.9990 | 0.9999 | Bacteria | CE |
| dbCAN_4:DIAMOND | 0.9995 | 0.0008 | 0.9990 | 1.0000 | Bacteria | CE |
| dbCAN_4:dbCAN-sub | 0.9995 | 0.0008 | 0.9991 | 1.0000 | Bacteria | CE |
| CUPP | 0.9994 | 0.0009 | 0.9989 | 1.0000 | Bacteria | CE |
| dbCAN_4 | 0.9993 | 0.0012 | 0.9988 | 0.9999 | Eukaryote | CE |
| dbCAN_4:HMMER | 0.9992 | 0.0013 | 0.9986 | 0.9999 | Eukaryote | CE |
| dbCAN_4:DIAMOND | 0.9994 | 0.0009 | 0.9990 | 0.9999 | Eukaryote | CE |
| dbCAN_4:dbCAN-sub | 0.9993 | 0.0012 | 0.9988 | 0.9999 | Eukaryote | CE |
| CUPP | 0.9992 | 0.0012 | 0.9985 | 0.9998 | Eukaryote | CE |
| dbCAN_4 | 1.0000 | NA | NaN | NaN | All | AA |
| dbCAN_4:HMMER | 1.0000 | NA | NaN | NaN | All | AA |
| dbCAN_4:DIAMOND | 0.9998 | NA | NaN | NaN | All | AA |
| dbCAN_4:dbCAN-sub | 1.0000 | NA | NaN | NaN | All | AA |
| CUPP | 1.0000 | NA | NaN | NaN | All | AA |
| dbCAN_4 | 0.9991 | 0.0013 | 0.9984 | 0.9998 | Bacteria | AA |
| dbCAN_4:HMMER | 0.9991 | 0.0014 | 0.9983 | 0.9999 | Bacteria | AA |
| dbCAN_4:DIAMOND | 0.9990 | 0.0013 | 0.9983 | 0.9998 | Bacteria | AA |
| dbCAN_4:dbCAN-sub | 0.9991 | 0.0014 | 0.9983 | 0.9998 | Bacteria | AA |
| CUPP | 0.9986 | 0.0017 | 0.9977 | 0.9996 | Bacteria | AA |
| dbCAN_4 | 0.9996 | 0.0007 | 0.9992 | 0.9999 | Eukaryote | AA |
| dbCAN_4:HMMER | 0.9996 | 0.0007 | 0.9992 | 0.9999 | Eukaryote | AA |
| dbCAN_4:DIAMOND | 0.9995 | 0.0006 | 0.9992 | 0.9999 | Eukaryote | AA |
| dbCAN_4:dbCAN-sub | 0.9996 | 0.0007 | 0.9992 | 0.9999 | Eukaryote | AA |
| CUPP | 0.9993 | 0.0009 | 0.9989 | 0.9998 | Eukaryote | AA |
| dbCAN_4 | 0.9995 | 0.0011 | 0.9992 | 0.9999 | All | CBM |
| dbCAN_4:HMMER | 0.9987 | 0.0042 | 0.9975 | 0.9999 | All | CBM |
| dbCAN_4:DIAMOND | 0.9994 | 0.0016 | 0.9989 | 0.9999 | All | CBM |
| dbCAN_4:dbCAN-sub | 0.9996 | 0.0008 | 0.9994 | 0.9998 | All | CBM |
| CUPP | 0.9968 | 0.0054 | 0.9952 | 0.9984 | All | CBM |
| dbCAN_4 | 0.9986 | 0.0026 | 0.9976 | 0.9997 | Bacteria | CBM |
| dbCAN_4:HMMER | 0.9974 | 0.0047 | 0.9955 | 0.9994 | Bacteria | CBM |
| dbCAN_4:DIAMOND | 0.9996 | 0.0006 | 0.9993 | 0.9998 | Bacteria | CBM |
| dbCAN_4:dbCAN-sub | 0.9985 | 0.0027 | 0.9974 | 0.9996 | Bacteria | CBM |
| CUPP | 0.9961 | 0.0049 | 0.9941 | 0.9982 | Bacteria | CBM |
| dbCAN_4 | 0.9995 | 0.0012 | 0.9992 | 0.9998 | Eukaryote | CBM |
| dbCAN_4:HMMER | 0.9989 | 0.0030 | 0.9981 | 0.9997 | Eukaryote | CBM |
| dbCAN_4:DIAMOND | 0.9997 | 0.0009 | 0.9994 | 0.9999 | Eukaryote | CBM |
| dbCAN_4:dbCAN-sub | 0.9995 | 0.0011 | 0.9992 | 0.9998 | Eukaryote | CBM |
| CUPP | 0.9978 | 0.0037 | 0.9968 | 0.9988 | Eukaryote | CBM |
13 CAZy family multilabel classification tax performance
| Prediction_tool | Lower CI | Mean | Upper CI | Standard Deviation | Tax_group |
|---|---|---|---|---|---|
| dbCAN_4 | 0.9997 | 0.9998 | 0.9998 | 0.0011 | All |
| dbCAN_4:HMMER | 0.9996 | 0.9996 | 0.9996 | 0.0014 | All |
| dbCAN_4:DIAMOND | 0.9998 | 0.9998 | 0.9998 | 0.0009 | All |
| dbCAN_4:dbCAN-sub | 0.9997 | 0.9998 | 0.9998 | 0.0011 | All |
| CUPP | 0.9994 | 0.9994 | 0.9995 | 0.0015 | All |
| dbCAN_4 | 0.9998 | 0.9998 | 0.9998 | 0.0011 | Bacteria |
| dbCAN_4:HMMER | 0.9996 | 0.9996 | 0.9996 | 0.0013 | Bacteria |
| dbCAN_4:DIAMOND | 0.9998 | 0.9998 | 0.9998 | 0.0010 | Bacteria |
| dbCAN_4:dbCAN-sub | 0.9998 | 0.9998 | 0.9998 | 0.0011 | Bacteria |
| CUPP | 0.9994 | 0.9994 | 0.9995 | 0.0016 | Bacteria |
| dbCAN_4 | 0.9997 | 0.9997 | 0.9998 | 0.0011 | Eukaryote |
| dbCAN_4:HMMER | 0.9995 | 0.9996 | 0.9996 | 0.0014 | Eukaryote |
| dbCAN_4:DIAMOND | 0.9998 | 0.9999 | 0.9999 | 0.0008 | Eukaryote |
| dbCAN_4:dbCAN-sub | 0.9997 | 0.9997 | 0.9997 | 0.0011 | Eukaryote |
| CUPP | 0.9994 | 0.9995 | 0.9995 | 0.0014 | Eukaryote |
13.1 Testing for statistically significant differences in the ARI
All classifiers achieved a mean RI across all proteins of greater than 0.99. However, the ARI was more variable between the tools. Therefore, a two-way ANOVA was performed to test for statistially significant differences between the taxonomic kingdoms of the test sets and the CAZyme classifiers.
Statistically significant difference was detected so follow up with a Tukey test to determine if there are differences between groups.
## Tukey multiple comparisons of means
## 95% family-wise confidence level
##
## Fit: aov(formula = Adjusted_Rand_index_freq ~ Tax_group * Prediction_tool, data = fam_ari_df.all)
##
## $`Tax_group:Prediction_tool`
## diff
## Bacteria:dbCAN_4-All:dbCAN_4 3.530914e-03
## Eukaryote:dbCAN_4-All:dbCAN_4 -3.530914e-03
## All:dbCAN_4:HMMER-All:dbCAN_4 -3.177773e-02
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4 -3.176570e-02
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4 -3.178976e-02
## All:dbCAN_4:DIAMOND-All:dbCAN_4 9.785332e-03
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4 4.523891e-03
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4 1.504677e-02
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4 5.420138e-04
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4 6.328372e-03
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4 -5.244344e-03
## All:CUPP-All:dbCAN_4 -5.267945e-02
## Bacteria:CUPP-All:dbCAN_4 -4.903271e-02
## Eukaryote:CUPP-All:dbCAN_4 -5.632618e-02
## Eukaryote:dbCAN_4-Bacteria:dbCAN_4 -7.061828e-03
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4 -3.530864e-02
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4 -3.529661e-02
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4 -3.532067e-02
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 6.254418e-03
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 9.929766e-04
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 1.151586e-02
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 -2.988900e-03
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 2.797458e-03
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 -8.775258e-03
## All:CUPP-Bacteria:dbCAN_4 -5.621036e-02
## Bacteria:CUPP-Bacteria:dbCAN_4 -5.256362e-02
## Eukaryote:CUPP-Bacteria:dbCAN_4 -5.985709e-02
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -2.824681e-02
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -2.823478e-02
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -2.825884e-02
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 1.331625e-02
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 8.054805e-03
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 1.857769e-02
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 4.072928e-03
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 9.859286e-03
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 -1.713430e-03
## All:CUPP-Eukaryote:dbCAN_4 -4.914853e-02
## Bacteria:CUPP-Eukaryote:dbCAN_4 -4.550180e-02
## Eukaryote:CUPP-Eukaryote:dbCAN_4 -5.279527e-02
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:HMMER 1.202909e-05
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:HMMER -1.202909e-05
## All:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER 4.156306e-02
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER 3.630162e-02
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER 4.682450e-02
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER 3.231974e-02
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER 3.810610e-02
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER 2.653338e-02
## All:CUPP-All:dbCAN_4:HMMER -2.090172e-02
## Bacteria:CUPP-All:dbCAN_4:HMMER -1.725498e-02
## Eukaryote:CUPP-All:dbCAN_4:HMMER -2.454845e-02
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:HMMER -2.405818e-05
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER 4.155103e-02
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER 3.628959e-02
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER 4.681247e-02
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER 3.230771e-02
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER 3.809407e-02
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER 2.652135e-02
## All:CUPP-Bacteria:dbCAN_4:HMMER -2.091375e-02
## Bacteria:CUPP-Bacteria:dbCAN_4:HMMER -1.726701e-02
## Eukaryote:CUPP-Bacteria:dbCAN_4:HMMER -2.456048e-02
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER 4.157509e-02
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER 3.631365e-02
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER 4.683653e-02
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER 3.233177e-02
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER 3.811813e-02
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER 2.654541e-02
## All:CUPP-Eukaryote:dbCAN_4:HMMER -2.088969e-02
## Bacteria:CUPP-Eukaryote:dbCAN_4:HMMER -1.724295e-02
## Eukaryote:CUPP-Eukaryote:dbCAN_4:HMMER -2.453642e-02
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND -5.261442e-03
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND 5.261442e-03
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND -9.243319e-03
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND -3.456961e-03
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND -1.502968e-02
## All:CUPP-All:dbCAN_4:DIAMOND -6.246478e-02
## Bacteria:CUPP-All:dbCAN_4:DIAMOND -5.881804e-02
## Eukaryote:CUPP-All:dbCAN_4:DIAMOND -6.611151e-02
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:DIAMOND 1.052288e-02
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND -3.981877e-03
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND 1.804481e-03
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND -9.768235e-03
## All:CUPP-Bacteria:dbCAN_4:DIAMOND -5.720334e-02
## Bacteria:CUPP-Bacteria:dbCAN_4:DIAMOND -5.355660e-02
## Eukaryote:CUPP-Bacteria:dbCAN_4:DIAMOND -6.085007e-02
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND -1.450476e-02
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND -8.718402e-03
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND -2.029112e-02
## All:CUPP-Eukaryote:dbCAN_4:DIAMOND -6.772622e-02
## Bacteria:CUPP-Eukaryote:dbCAN_4:DIAMOND -6.407948e-02
## Eukaryote:CUPP-Eukaryote:dbCAN_4:DIAMOND -7.137295e-02
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub 5.786358e-03
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub -5.786358e-03
## All:CUPP-All:dbCAN_4:dbCAN-sub -5.322146e-02
## Bacteria:CUPP-All:dbCAN_4:dbCAN-sub -4.957472e-02
## Eukaryote:CUPP-All:dbCAN_4:dbCAN-sub -5.686819e-02
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:dbCAN-sub -1.157272e-02
## All:CUPP-Bacteria:dbCAN_4:dbCAN-sub -5.900782e-02
## Bacteria:CUPP-Bacteria:dbCAN_4:dbCAN-sub -5.536108e-02
## Eukaryote:CUPP-Bacteria:dbCAN_4:dbCAN-sub -6.265455e-02
## All:CUPP-Eukaryote:dbCAN_4:dbCAN-sub -4.743510e-02
## Bacteria:CUPP-Eukaryote:dbCAN_4:dbCAN-sub -4.378837e-02
## Eukaryote:CUPP-Eukaryote:dbCAN_4:dbCAN-sub -5.108184e-02
## Bacteria:CUPP-All:CUPP 3.646735e-03
## Eukaryote:CUPP-All:CUPP -3.646735e-03
## Eukaryote:CUPP-Bacteria:CUPP -7.293471e-03
## lwr
## Bacteria:dbCAN_4-All:dbCAN_4 -0.0071615537
## Eukaryote:dbCAN_4-All:dbCAN_4 -0.0142233818
## All:dbCAN_4:HMMER-All:dbCAN_4 -0.0405080904
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4 -0.0424581657
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4 -0.0424822239
## All:dbCAN_4:DIAMOND-All:dbCAN_4 0.0010549690
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4 -0.0061685770
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4 0.0043543063
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4 -0.0081883496
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4 -0.0043640961
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4 -0.0159368118
## All:CUPP-All:dbCAN_4 -0.0614098085
## Bacteria:CUPP-All:dbCAN_4 -0.0597251776
## Eukaryote:CUPP-All:dbCAN_4 -0.0670186482
## Eukaryote:dbCAN_4-Bacteria:dbCAN_4 -0.0194084264
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4 -0.0460011089
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4 -0.0476432103
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4 -0.0476672685
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 -0.0044380494
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 -0.0113536216
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 -0.0008307383
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 -0.0136813680
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 -0.0095491407
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 -0.0211218564
## All:CUPP-Bacteria:dbCAN_4 -0.0669028270
## Bacteria:CUPP-Bacteria:dbCAN_4 -0.0649102222
## Eukaryote:CUPP-Bacteria:dbCAN_4 -0.0722036928
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -0.0389392808
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -0.0405813822
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -0.0406054404
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 0.0026237787
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 -0.0042917935
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 0.0062310899
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 -0.0066195399
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 -0.0024873126
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 -0.0140600282
## All:CUPP-Eukaryote:dbCAN_4 -0.0598409988
## Bacteria:CUPP-Eukaryote:dbCAN_4 -0.0578483940
## Eukaryote:CUPP-Eukaryote:dbCAN_4 -0.0651418647
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:HMMER -0.0106804387
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:HMMER -0.0107044968
## All:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER 0.0328326961
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER 0.0256091500
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER 0.0361320334
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER 0.0235893775
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER 0.0274136309
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER 0.0158409153
## All:CUPP-All:dbCAN_4:HMMER -0.0296320814
## Bacteria:CUPP-All:dbCAN_4:HMMER -0.0279474505
## Eukaryote:CUPP-All:dbCAN_4:HMMER -0.0352409211
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:HMMER -0.0123706564
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER 0.0308585626
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER 0.0239429904
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER 0.0344658738
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER 0.0216152440
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER 0.0257474713
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER 0.0141747557
## All:CUPP-Bacteria:dbCAN_4:HMMER -0.0316062149
## Bacteria:CUPP-Bacteria:dbCAN_4:HMMER -0.0296136101
## Eukaryote:CUPP-Bacteria:dbCAN_4:HMMER -0.0369070807
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER 0.0308826208
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER 0.0239670486
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER 0.0344899320
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER 0.0216393022
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER 0.0257715295
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER 0.0141988139
## All:CUPP-Eukaryote:dbCAN_4:HMMER -0.0315821567
## Bacteria:CUPP-Eukaryote:dbCAN_4:HMMER -0.0295895519
## Eukaryote:CUPP-Eukaryote:dbCAN_4:HMMER -0.0368830226
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND -0.0159539094
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND -0.0054310261
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND -0.0179736820
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND -0.0141494285
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND -0.0257221442
## All:CUPP-All:dbCAN_4:DIAMOND -0.0711951409
## Bacteria:CUPP-All:dbCAN_4:DIAMOND -0.0695105100
## Eukaryote:CUPP-All:dbCAN_4:DIAMOND -0.0768039806
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:DIAMOND -0.0018237149
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND -0.0146743447
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND -0.0105421174
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND -0.0221148330
## All:CUPP-Bacteria:dbCAN_4:DIAMOND -0.0678958036
## Bacteria:CUPP-Bacteria:dbCAN_4:DIAMOND -0.0659031988
## Eukaryote:CUPP-Bacteria:dbCAN_4:DIAMOND -0.0731966694
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND -0.0251972280
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND -0.0210650007
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND -0.0326377164
## All:CUPP-Eukaryote:dbCAN_4:DIAMOND -0.0784186870
## Bacteria:CUPP-Eukaryote:dbCAN_4:DIAMOND -0.0764260822
## Eukaryote:CUPP-Eukaryote:dbCAN_4:DIAMOND -0.0837195528
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub -0.0049061099
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub -0.0164788256
## All:CUPP-All:dbCAN_4:dbCAN-sub -0.0619518223
## Bacteria:CUPP-All:dbCAN_4:dbCAN-sub -0.0602671914
## Eukaryote:CUPP-All:dbCAN_4:dbCAN-sub -0.0675606620
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:dbCAN-sub -0.0239193139
## All:CUPP-Bacteria:dbCAN_4:dbCAN-sub -0.0697002845
## Bacteria:CUPP-Bacteria:dbCAN_4:dbCAN-sub -0.0677076797
## Eukaryote:CUPP-Bacteria:dbCAN_4:dbCAN-sub -0.0750011503
## All:CUPP-Eukaryote:dbCAN_4:dbCAN-sub -0.0581275689
## Bacteria:CUPP-Eukaryote:dbCAN_4:dbCAN-sub -0.0561349641
## Eukaryote:CUPP-Eukaryote:dbCAN_4:dbCAN-sub -0.0634284347
## Bacteria:CUPP-All:CUPP -0.0070457324
## Eukaryote:CUPP-All:CUPP -0.0143392031
## Eukaryote:CUPP-Bacteria:CUPP -0.0196400689
## upr p adj
## Bacteria:dbCAN_4-All:dbCAN_4 0.0142233818 0.9987280
## Eukaryote:dbCAN_4-All:dbCAN_4 0.0071615537 0.9987280
## All:dbCAN_4:HMMER-All:dbCAN_4 -0.0230473637 0.0000000
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4 -0.0210732303 0.0000000
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4 -0.0210972884 0.0000000
## All:dbCAN_4:DIAMOND-All:dbCAN_4 0.0185156957 0.0121463
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4 0.0152163584 0.9842792
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4 0.0257392418 0.0001820
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4 0.0092723772 1.0000000
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4 0.0170208394 0.7945945
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4 0.0054481237 0.9440077
## All:CUPP-All:dbCAN_4 -0.0439490818 0.0000000
## Bacteria:CUPP-All:dbCAN_4 -0.0383402421 0.0000000
## Eukaryote:CUPP-All:dbCAN_4 -0.0456337127 0.0000000
## Eukaryote:dbCAN_4-Bacteria:dbCAN_4 0.0052847701 0.8330816
## All:dbCAN_4:HMMER-Bacteria:dbCAN_4 -0.0246161734 0.0000000
## Bacteria:dbCAN_4:HMMER-Bacteria:dbCAN_4 -0.0229500138 0.0000000
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4 -0.0229740720 0.0000000
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 0.0169468861 0.8084496
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 0.0133395749 1.0000000
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4 0.0238624583 0.0989228
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 0.0077035675 0.9998087
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 0.0151440558 0.9999851
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4 0.0035713402 0.5069153
## All:CUPP-Bacteria:dbCAN_4 -0.0455178915 0.0000000
## Bacteria:CUPP-Bacteria:dbCAN_4 -0.0402170256 0.0000000
## Eukaryote:CUPP-Bacteria:dbCAN_4 -0.0475104963 0.0000000
## All:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -0.0175543453 0.0000000
## Bacteria:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -0.0158881857 0.0000000
## Eukaryote:dbCAN_4:HMMER-Eukaryote:dbCAN_4 -0.0159122438 0.0000000
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 0.0240087142 0.0022424
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 0.0204014030 0.6559181
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4 0.0309242864 0.0000342
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 0.0147653956 0.9942948
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 0.0222058839 0.2996316
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4 0.0106331683 1.0000000
## All:CUPP-Eukaryote:dbCAN_4 -0.0384560633 0.0000000
## Bacteria:CUPP-Eukaryote:dbCAN_4 -0.0331551975 0.0000000
## Eukaryote:CUPP-Eukaryote:dbCAN_4 -0.0404486681 0.0000000
## Bacteria:dbCAN_4:HMMER-All:dbCAN_4:HMMER 0.0107044968 1.0000000
## Eukaryote:dbCAN_4:HMMER-All:dbCAN_4:HMMER 0.0106804387 1.0000000
## All:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER 0.0502934228 0.0000000
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER 0.0469940855 0.0000000
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:HMMER 0.0575169689 0.0000000
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER 0.0410501042 0.0000000
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER 0.0487985664 0.0000000
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:HMMER 0.0372258508 0.0000000
## All:CUPP-All:dbCAN_4:HMMER -0.0121713547 0.0000000
## Bacteria:CUPP-All:dbCAN_4:HMMER -0.0065625150 0.0000046
## Eukaryote:CUPP-All:dbCAN_4:HMMER -0.0138559856 0.0000000
## Eukaryote:dbCAN_4:HMMER-Bacteria:dbCAN_4:HMMER 0.0123225401 1.0000000
## All:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER 0.0522434981 0.0000000
## Bacteria:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER 0.0486361870 0.0000000
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:HMMER 0.0591590703 0.0000000
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER 0.0430001795 0.0000000
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER 0.0504406679 0.0000000
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:HMMER 0.0388679522 0.0000000
## All:CUPP-Bacteria:dbCAN_4:HMMER -0.0102212794 0.0000000
## Bacteria:CUPP-Bacteria:dbCAN_4:HMMER -0.0049204136 0.0002101
## Eukaryote:CUPP-Bacteria:dbCAN_4:HMMER -0.0122138842 0.0000000
## All:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER 0.0522675563 0.0000000
## Bacteria:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER 0.0486602451 0.0000000
## Eukaryote:dbCAN_4:DIAMOND-Eukaryote:dbCAN_4:HMMER 0.0591831285 0.0000000
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER 0.0430242377 0.0000000
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER 0.0504647260 0.0000000
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:HMMER 0.0388920104 0.0000000
## All:CUPP-Eukaryote:dbCAN_4:HMMER -0.0101972212 0.0000000
## Bacteria:CUPP-Eukaryote:dbCAN_4:HMMER -0.0048963554 0.0002169
## Eukaryote:CUPP-Eukaryote:dbCAN_4:HMMER -0.0121898260 0.0000000
## Bacteria:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND 0.0054310261 0.9425510
## Eukaryote:dbCAN_4:DIAMOND-All:dbCAN_4:DIAMOND 0.0159539094 0.9425510
## All:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND -0.0005129552 0.0258719
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND 0.0072355070 0.9989922
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:DIAMOND -0.0043372087 0.0001869
## All:CUPP-All:dbCAN_4:DIAMOND -0.0537344142 0.0000000
## Bacteria:CUPP-All:dbCAN_4:DIAMOND -0.0481255745 0.0000000
## Eukaryote:CUPP-All:dbCAN_4:DIAMOND -0.0554190451 0.0000000
## Eukaryote:dbCAN_4:DIAMOND-Bacteria:dbCAN_4:DIAMOND 0.0228694816 0.2005536
## All:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND 0.0067105908 0.9954617
## Bacteria:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND 0.0141510792 0.9999999
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:DIAMOND 0.0025783635 0.3151381
## All:CUPP-Bacteria:dbCAN_4:DIAMOND -0.0465108681 0.0000000
## Bacteria:CUPP-Bacteria:dbCAN_4:DIAMOND -0.0412100023 0.0000000
## Eukaryote:CUPP-Bacteria:dbCAN_4:DIAMOND -0.0485034729 0.0000000
## All:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND -0.0038122925 0.0004145
## Bacteria:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND 0.0036281958 0.5187119
## Eukaryote:dbCAN_4:dbCAN-sub-Eukaryote:dbCAN_4:DIAMOND -0.0079445198 0.0000026
## All:CUPP-Eukaryote:dbCAN_4:DIAMOND -0.0570337515 0.0000000
## Bacteria:CUPP-Eukaryote:dbCAN_4:DIAMOND -0.0517328856 0.0000000
## Eukaryote:CUPP-Eukaryote:dbCAN_4:DIAMOND -0.0590263563 0.0000000
## Bacteria:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub 0.0164788256 0.8840234
## Eukaryote:dbCAN_4:dbCAN-sub-All:dbCAN_4:dbCAN-sub 0.0049061099 0.8840234
## All:CUPP-All:dbCAN_4:dbCAN-sub -0.0444910956 0.0000000
## Bacteria:CUPP-All:dbCAN_4:dbCAN-sub -0.0388822559 0.0000000
## Eukaryote:CUPP-All:dbCAN_4:dbCAN-sub -0.0461757265 0.0000000
## Eukaryote:dbCAN_4:dbCAN-sub-Bacteria:dbCAN_4:dbCAN-sub 0.0007738826 0.0946519
## All:CUPP-Bacteria:dbCAN_4:dbCAN-sub -0.0483153490 0.0000000
## Bacteria:CUPP-Bacteria:dbCAN_4:dbCAN-sub -0.0430144832 0.0000000
## Eukaryote:CUPP-Bacteria:dbCAN_4:dbCAN-sub -0.0503079538 0.0000000
## All:CUPP-Eukaryote:dbCAN_4:dbCAN-sub -0.0367426334 0.0000000
## Bacteria:CUPP-Eukaryote:dbCAN_4:dbCAN-sub -0.0314417676 0.0000000
## Eukaryote:CUPP-Eukaryote:dbCAN_4:dbCAN-sub -0.0387352382 0.0000000
## Bacteria:CUPP-All:CUPP 0.0143392031 0.9981945
## Eukaryote:CUPP-All:CUPP 0.0070457324 0.9981945
## Eukaryote:CUPP-Bacteria:CUPP 0.0050531276 0.7968833